BDNF Protein 組換え体(リコンビナント)タンパク質 | Recombinant Human/Mouse/Rat/Canine/Equine BDNF Protein

掲載日情報:2018/02/07 現在Webページ番号:215989

R&D Systems社製の高品質なBDNF Proteinの組換え体タンパク質(Recombinant Human/Mouse/Rat/Canine/Equine BDNF Protein)です。
本製品は研究用です。研究用以外には使用できません。

[在庫・価格 :2025年05月06日 15時55分現在]

※ 表示されている納期は弊社に在庫が無く、取り寄せた場合の納期目安となります。
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納期 文献数
Recombinant Human BDNF Protein
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本製品は製品内容等が変更されました
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0
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説明文
Genbank No: 627
法規制等 カルタヘナ該当品
保存条件 法規備考
掲載カタログ

製品記事
関連記事
Recombinant Human BDNF Protein, CF
変更先製品
本製品は製品内容等が変更されました
変更先製品
0
  • メーカーサイト
  • お問い合わせ
説明文
Genbank No: 627
法規制等 カルタヘナ該当品
保存条件 法規備考
掲載カタログ

製品記事
関連記事

[在庫・価格 :2025年05月06日 15時55分現在]

※ 表示されている納期は弊社に在庫が無く、取り寄せた場合の納期目安となります。

Recombinant Human BDNF Protein

文献数: 0

  • 商品コード:248-BD-250
  • メーカー:RSD
  • 包装:250μg
  • 本製品は製品内容等が変更されました 変更先製品

説明文 Genbank No: 627
法規制等 カルタヘナ該当品
保存条件 法規備考
掲載カタログ

製品記事
関連記事
変更先製品

Recombinant Human BDNF Protein, CF

文献数: 0

  • 商品コード:248-BD-250/CF
  • メーカー:RSD
  • 包装:250μg
  • 本製品は製品内容等が変更されました 変更先製品

説明文 Genbank No: 627
法規制等 カルタヘナ該当品
保存条件 法規備考
掲載カタログ

製品記事
関連記事
変更先製品

バルク注文に関して

バルク包装品も承ります。お気軽にお問合せ下さい。

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CF(Carrier-Free)とは?

R&D Systems社組換え体タンパク質製品では通常ウシ血清アルブミン(BSA)をキャリアタンパク質として加えています。キャリアタンパク質を加えることで組換え体タンパク質の安定性が高まり、使用期限が長くなります。また、より濃度の低い溶液での保管も可能となります。CF製品はBSAが含まれない製品となります。一般的に細胞培養や、ELISAのスタンダードにはBSA含有製品を推奨しています。CF製品はBSAが影響してしまうアプリケーションに推奨されます。

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Product Details

Source
Spodoptera frugiperda, Sf 21 (baculovirus)-derivedHis129-Arg247
Accession #
P23560
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Predicted Molecular Mass
13.5 kDa
SDS-PAGE
13-14 kDa, reducing conditions
Activity
Abrineurin; ANON2; BDNF; brain-derived neurotrophic factor; BULN2; MGC34632; neurotrophin

Bioactivity
Recombinant Human BDNF (Catalog #248‑BD) stimulates cell proliferation in the BaF mouse pro-B cell line transfected with TrkB. The ED50 for this effect is 0.2-2 ng/mL.
SDS-PAGE
1 μg/lane of Recombinant Human BDNF was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 13 kDa.

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Related Product & Information

Entrez Gene IDs
627 (Human); 12064 (Mouse); 24225 (Rat)
Background
BDNF
Brain-derived neurotrophic factor (BDNF) is a member of the NGF family of neurotrophic factors (also named neurotrophins) that are required for the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous system. The neurotrophin family is comprised of at least four proteins including NGF, BDNF, NT-3, and NT-4/5. These secreted cytokines are synthesized as prepropeptides that are proteolytically processed to generate the mature proteins (1, 2). All neurotrophins have six conserved cysteine residues that are involved in the formation of three disulfide bonds and all share approximately 55% sequence identity at the amino acid level. Similarly to NGF, bioactive BDNF is predicted to be a non-covalently linked homodimer. BDNF cDNA encodes a 247 amino acid residue precursor protein with a signal peptide and a proprotein that are cleaved to yield the 119 amino acid residue mature BDNF. The amino acid sequence of mature BDNF is identical in all mammals examined. High levels of expression of BDNF have been detected in the hippocampus, cerebellum, fetal eye and placenta. In addition, low levels of BDNF expression are also found in the pituitary gland, spinal cord, heart, lung and skeletal muscle. BDNF binds with high affinity and specifically activates the TrkB tyrosine kinase receptor (3).

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Citations

R&D Systems personnel manually curate a database that contains references using R&D Systems products.
The data collected includes not only links to publications in PubMed,
but also provides information about sample types, species, and experimental conditions.
MANF Promotes Differentiation and Migration of Neural Progenitor Cells with Potential Neural Regenerative Effects in Stroke
Authors: KY Tseng, JE Anttila, K Khodosevic, RK Tuominen, M Lindahl, A Domanskyi, M Airavaara
Mol. Ther., 2017;0(0):.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Overexpression of matrix metalloproteinase-9 (MMP-9) rescues insulin-mediated impairment in the 5XFAD model of Alzheimer's disease
Authors: A Kaminari, N Giannakas, A Tzinia, EC Tsilibary
Sci Rep, 2017;7(1):683.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cells
Authors: Y Qi, XJ Zhang, N Renier, Z Wu, T Atkin, Z Sun, MZ Ozair, J Tchieu, B Zimmer, F Fattahi, Y Ganat, R Azevedo, N Zeltner, AH Brivanlou, M Karayiorgo, J Gogos, M Tomishima, M Tessier-La, SH Shi, L Studer
Nat. Biotechnol, 2017;0(0):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Neurotoxic reactive astrocytes are induced by activated microglia
Authors: SA Liddelow, KA Guttenplan, LE Clarke, FC Bennett, CJ Bohlen, L Schirmer, ML Bennett, AE Mnch, WS Chung, TC Peterson, DK Wilton, A Frouin, BA Napier, N Panicker, M Kumar, MS Buckwalter, DH Rowitch, VL Dawson, TM Dawson, B Stevens, BA Barres
Nature, 2017;541(7638):481-487.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
A hypomorphic PIGA gene mutation causes severe defects in neuron development and susceptibility to complement-mediated toxicity in a human iPSC model
Authors: X Yuan, Z Li, AC Baines, E Gavriilaki, Z Ye, Z Wen, EM Braunstein, LG Biesecker, L Cheng, X Dong, RA Brodsky
PLoS ONE, 2017;12(4):e0174074.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Embryonic Stem Cell-Derived Neurons Grown on Multi-Electrode Arrays as a Novel In vitro Bioassay for the Detection of Clostridium botulinum Neurotoxins
Authors: SP Jenkinson, D Grandgirar, M Heidemann, A Tscherter, MA Avondet, SL Leib
Front Pharmacol, 2017;8(0):73.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Presynaptic morphology and vesicular composition determine vesicle dynamics in mouse central synapses
Authors: L Guillaud, D Dimitrov, T Takahashi
Elife, 2017;6(0):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Novel combinatorial screening identifies neurotrophic factors for selective classes of motor neurons
Authors: S Schaller, D Buttigieg, A Alory, A Jacquier, M Barad, M Merchant, D Gentien, P de la Gran, G Haase
Proc. Natl. Acad. Sci. U.S.A, 2017;114(12):E2486-E2493.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Differentiation of nestin?negative human hair follicle outer root sheath cells into neurons in�vitro
Authors: W Wu, XL Wu, YQ Ji, Z Gao
Mol Med Rep, 2017;0(0):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
EndophilinAs regulate endosomal sorting of BDNF-TrkB to mediate survival signaling in hippocampal neurons
Authors: K Burk, JD Murdoch, S Freytag, M Koenig, V Bharat, R Markworth, S Burkhardt, A Fischer, C Dean
Sci Rep, 2017;7(1):2149.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Capturing the biology of disease severity in a PSC-based model of familial dysautonomia
Authors: N Zeltner, F Fattahi, NC Dubois, N Saurat, F Lafaille, L Shang, B Zimmer, J Tchieu, MA Soliman, G Lee, JL Casanova, L Studer
Nat. Med., 2016;22(12):1421-1427.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Microfabric Vessels for Embryoid Body Formation and Rapid Differentiation of Pluripotent Stem Cells
Sci Rep, 2016;6(0):31063.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Effects of Feeder Cells on Dopaminergic Differentiation of Human Embryonic Stem Cells
Authors: Z Zhao, Y Ma, Z Chen, Q Liu, Q Li, D Kong, K Yuan, L Hu, T Wang, X Chen, Y Peng, W Jiang, Y Yu, X Liu
Front Cell Neurosci, 2016;10(0):291.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
MicroRNA-302 switch to identify and eliminate undifferentiated human pluripotent stem cells
Sci Rep, 2016;6(0):32532.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Sustained synchronized neuronal network activity in a human astrocyte co-culture system
Sci Rep, 2016;6(0):36529.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Neurotrophin-3 Regulates Synapse Development by Modulating TrkC-PTP? Synaptic Adhesion and Intracellular Signaling Pathways
J Neurosci, 2016;36(17):4816-31.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Hypomorphism of Fto and Rpgrip1l causes obesity in mice
Authors: G Stratigopo, LC Burnett, R Rausch, R Gill, DB Penn, AA Skowronski, CA LeDuc, AJ Lanzano, P Zhang, DR Storm, D Egli, RL Leibel
J Clin Invest, 2016;0(0):.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Dopamine Receptor Antagonists Enhance Proliferation and Neurogenesis of Midbrain Lmx1a-expressing Progenitors
Authors: Eva Hedlund
Sci Rep, 2016;6(0):26448.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Generation of Dopamine Neurons from Rodent Fibroblasts through the Expandable Neural Precursor Cell Stage.
Authors: Lim M, Chang M, Kim S, Yi S, Suh-Kim H, Jung S, Kim M, Kim J, Lee Y, Lee S, Kim D, Lee S, Park C
J Biol Chem, 2015;290(28):17401-14.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Modeling the Early Phenotype at the Neuromuscular Junction of Spinal Muscular Atrophy Using Patient-Derived iPSCs.
Authors: Yoshida M, Kitaoka S, Egawa N, Yamane M, Ikeda R, Tsukita K, Amano N, Watanabe A, Morimoto M, Takahashi J, Hosoi H, Nakahata T, Inoue H, Saito M
Stem Cell Reports, 2015;4(4):561-8.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viability.
Authors: Devlin, Anna-Cla, Burr, Karen, Borooah, Shyamang, Foster, Joshua D, Cleary, Elaine M, Geti, Imbisaat, Vallier, Ludovic, Shaw, Christop, Chandran, Siddhart, Miles, Gareth B
Nat Commun, 2015;6(0):5999.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Role of Hypoxia-Induced Brain Derived Neurotrophic Factor in Human Pulmonary Artery Smooth Muscle.
Authors: Hartman W, Helan M, Smelter D, Sathish V, Thompson M, Pabelick C, Johnson B, Prakash Y
PLoS ONE, 2015;10(7):e0129489.
Species: Human
Sample Type: Whole Tissue
Application: Bioassay
Noggin Over-Expressing Mouse Embryonic Fibroblasts and MS5 Stromal Cells Enhance Directed Differentiation of Dopaminergic Neurons from Human Embryonic Stem Cells.
Authors: Lim M, Shin M, Lee S, Minn Y, Hoh J, Cho Y, Kim D, Lee S, Kim C, Park C
PLoS ONE, 2015;10(9):e0138460.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Neuropeptide Y receptor Y5 as an inducible pro-survival factor in neuroblastoma: implications for tumor chemoresistance.
Authors: Czarnecka M, Trinh E, Lu C, Kuan-Celarier A, Galli S, Hong S, Tilan J, Talisman N, Izycka-Swieszewska E, Tsuei J, Yang C, Martin S, Horton M, Christian D, Everhart L, Maheswaran I, Kitlinska J
Oncogene, 2015;34(24):3131-43.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease.
Authors: Laguna A, Schintu N, Nobre A, Alvarsson A, Volakakis N, Jacobsen J, Gomez-Galan M, Sopova E, Joodmardi E, Yoshitake T, Deng Q, Kehr J, Ericson J, Svenningsson P, Shupliakov O, Perlmann T
Nat Neurosci, 2015;18(6):826-35.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Generation of neuropeptidergic hypothalamic neurons from human pluripotent stem cells.
Authors: Merkle F, Maroof A, Wataya T, Sasai Y, Studer L, Eggan K, Schier A
Development, 2015;142(4):633-43.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Generation of retinal ganglion cells with functional axons from human induced pluripotent stem cells.
Authors: Tanaka, Taku, Yokoi, Tadashi, Tamalu, Fuminobu, Watanabe, Shu-Ichi, Nishina, Sachiko, Azuma, Noriyuki
Sci Rep, 2015;5(0):8344.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Neuroprotective effects of oligodendrocyte progenitor cell transplantation in premature rat brain following hypoxic-ischemic injury.
Authors: Chen, Long-Xia, Ma, Si-Min, Zhang, Peng, Fan, Zi-Chuan, Xiong, Man, Cheng, Guo-Qian, Yang, Yi, Qiu, Zi-Long, Zhou, Wen-Hao, Li, Jin
PLoS ONE, 2015;10(3):e0115997.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts.
Authors: Wainger B, Buttermore E, Oliveira J, Mellin C, Lee S, Saber W, Wang A, Ichida J, Chiu I, Barrett L, Huebner E, Bilgin C, Tsujimoto N, Brenneis C, Kapur K, Rubin L, Eggan K, Woolf C
Nat Neurosci, 2015;18(1):17-24.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Highly efficient generation of induced neurons from human fibroblasts that survive transplantation into the adult rat brain.
Authors: Pereira, Maria, Pfisterer, Ulrich, Rylander, Daniella, Torper, Olof, Lau, Shong, Lundblad, Martin, Grealish, Shane, Parmar, Malin
Sci Rep, 2014;4(0):6330.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Constitutively active TrkB confers an aggressive transformed phenotype to a neural crest-derived cell line.
Authors: Dewitt J, Ochoa V, Urschitz J, Elston M, Moisyadi S, Nishi R
Oncogene, 2014;33(8):977-85.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Infralimbic BDNF/TrkB enhancement of GluN2B currents facilitates extinction of a cocaine-conditioned place preference.
Authors: Otis J, Fitzgerald M, Mueller D
J Neurosci, 2014;34(17):6057-64.
Species: Rat
Sample Type: In Vivo
Application: In Vivo
Selective lentiviral gene delivery to CD133-expressing human glioblastoma stem cells.
Authors: Bayin, N Sumru, Modrek, Aram S, Dietrich, August, Lebowitz, Jonathan, Abel, Tobias, Song, Hae-Ri, Schober, Markus, Zagzag, David, Buchholz, Christia, Chao, Moses V, Placantonakis, Dimitris
PLoS ONE, 2014;9(12):e116114.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Hybrid multiphoton volumetric functional imaging of large-scale bioengineered neuronal networks.
Authors: Dana, Hod, Marom, Anat, Paluch, Shir, Dvorkin, Roman, Brosh, Inbar, Shoham, Shy
Nat Commun, 2014;5(0):3997.
Species: Rat
Sample Type: Whole Cells
Application: Bioassay
A time course analysis of the electrophysiological properties of neurons differentiated from human induced pluripotent stem cells (iPSCs).
Authors: Pre D, Nestor M, Sproul A, Jacob S, Koppensteiner P, Chinchalongporn V, Zimmer M, Yamamoto A, Noggle S, Arancio O
PLoS ONE, 2014;9(7):e103418.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Bicaudal-D1 regulates the intracellular sorting and signalling of neurotrophin receptors.
Authors: Terenzio M, Golding M, Russell M, Wicher K, Rosewell I, Spencer-Dene B, Ish-Horowicz D, Schiavo G
EMBO J, 2014;33(14):1582-98.
Species: N/A
Sample Type: Protein
Application: WB Standard
Reprogramming non-human primate somatic cells into functional neuronal cells by defined factors.
Authors: Zhou, Zhi, Kohda, Kazuhisa, Ibata, Keiji, Kohyama, Jun, Akamatsu, Wado, Yuzaki, Michisuk, Okano, Hirotaka, Sasaki, Erika, Okano, Hideyuki
Mol Brain, 2014;7(0):24.
Species: Primate - Callitrix jacchus (Common Marmoset)
Sample Type: Whole Cells
Application: Bioassay
Light-inducible receptor tyrosine kinases that regulate neurotrophin signalling.
Authors: Chang, Ki-Young, Woo, Doyeon, Jung, Hyunjin, Lee, Sangkyu, Kim, Sungsoo, Won, Joungha, Kyung, Taeyoon, Park, Hyerim, Kim, Nury, Yang, Hee Won, Park, Jae-Yong, Hwang, Eun Mi, Kim, Daesoo, Heo, Won Do
Nat Commun, 2014;5(0):4057.
Species: Rat
Sample Type: Whole Cells
Application: Bioassay
Local translation and retrograde axonal transport of CREB regulates IL-6-induced nociceptive plasticity.
Authors: Melemedjian O, Tillu D, Moy J, Asiedu M, Mandell E, Ghosh S, Dussor G, Price T
Mol Pain, 2014;10(0):45.
Species: Mouse
Sample Type: In Vivo
Application: In Vivo
NeuroD1 regulates survival and migration of neuroendocrine lung carcinomas via signaling molecules TrkB and NCAM.
Authors: Osborne, Jihan K, Larsen, Jill E, Shields, Misty D, Gonzales, Joshua X, Shames, David S, Sato, Mitsuo, Kulkarni, Ashwinik, Wistuba, Ignacio, Girard, Luc, Minna, John D, Cobb, Melanie
Proc Natl Acad Sci U S A, 2013;110(16):6524-9.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Self-assembling peptide nanofiber scaffolds enhance dopaminergic differentiation of mouse pluripotent stem cells in 3-dimensional culture.
Authors: Ni, Na, Hu, Yaohua, Ren, Huixia, Luo, Chuanmin, Li, Peng, Wan, Jian-Bo, Su, Huanxing
PLoS ONE, 2013;8(12):e84504.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
MicroRNA-based promotion of human neuronal differentiation and subtype specification.
Authors: Stappert L, Borghese L, Roese-Koerner B, Weinhold S, Koch P, Terstegge S, Uhrberg M, Wernet P, Brustle O
PLoS ONE, 2013;8(3):e59011.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Medial ganglionic eminence-like cells derived from human embryonic stem cells correct learning and memory deficits.
Authors: Liu Y, Weick J, Liu H, Krencik R, Zhang X, Ma L, Zhou G, Ayala M, Zhang S
Nat Biotechnol, 2013;31(5):440-7.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
ProNGF promotes neurite growth from a subset of NGF-dependent neurons by a p75NTR-dependent mechanism.
Authors: Howard, Laura, Wyatt, Sean, Nagappan, Guhan, Davies, Alun M
Development, 2013;140(10):2108-17.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Transcription factor-mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells.
Authors: Najm, Fadi J, Lager, Angela M, Zaremba, Anita, Wyatt, Krysta, Caprariello, Andrew V, Factor, Daniel C, Karl, Robert T, Maeda, Tadao, Miller, Robert H, Tesar, Paul J
Nat Biotechnol, 2013;31(5):426-33.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Enrichment and characterization of human dermal stem/progenitor cells by intracellular granularity.
Authors: Shim, Joong Hy, Lee, Tae Ryon, Shin, Dong Woo
Stem Cells Dev, 2013;22(8):1264-74.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Protein tyrosine phosphatase receptor type O inhibits trigeminal axon growth and branching by repressing TrkB and Ret signaling.
Authors: Gatto G, Dudanova I, Suetterlin P, Davies A, Drescher U, Bixby J, Klein R
J Neurosci, 2013;33(12):5399-410.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
A small molecule screen in stem-cell-derived motor neurons identifies a kinase inhibitor as a candidate therapeutic for ALS.
Authors: Yang Y, Gupta S, Kim K, Powers B, Cerqueira A, Wainger B, Ngo H, Rosowski K, Schein P, Ackeifi C, Arvanites A, Davidow L, Woolf C, Rubin L
Cell Stem Cell, 2013;12(6):713-26.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Inhibition of PIKfyve by YM-201636 dysregulates autophagy and leads to apoptosis-independent neuronal cell death.
Authors: Martin, Sally, Harper, Callista, May, Linda M, Coulson, Elizabet, Meunier, Frederic, Osborne, Shona L
PLoS ONE, 2013;8(3):e60152.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
A human Dravet syndrome model from patient induced pluripotent stem cells.
Authors: Higurashi N, Uchida T, Lossin C, Misumi Y, Okada Y, Akamatsu W, Imaizumi Y, Zhang B, Nabeshima K, Mori M, Katsurabayashi S, Shirasaka Y, Okano H, Hirose S
Mol Brain, 2013;6(0):19.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
BDNF regulates atypical PKC at spinal synapses to initiate and maintain a centralized chronic pain state.
Authors: Melemedjian O, Tillu D, Asiedu M, Mandell E, Moy J, Blute V, Taylor C, Ghosh S, Price T
Mol Pain, 2013;9(0):12.
Species: Mouse
Sample Type: In Vivo
Application: In Vivo
Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells.
Authors: Maroof A, Keros S, Tyson J, Ying S, Ganat Y, Merkle F, Liu B, Goulburn A, Stanley E, Elefanty A, Widmer H, Eggan K, Goldstein P, Anderson S, Studer L
Cell Stem Cell, 2013;12(5):559-72.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Neuregulin and BDNF induce a switch to NMDA receptor-dependent myelination by oligodendrocytes.
Authors: Lundgaard I, Luzhynskaya A, Stockley J, Wang Z, Evans K, Swire M, Volbracht K, Gautier H, Franklin R, Attwell D, Karadottir R
PLoS Biol, 2013;11(12):e1001743.
Species: Rat
Sample Type: Whole Cells
Application: cell culture
mTOR-dependent proliferation defect in human ES-derived neural stem cells affected by myotonic dystrophy type 1.
Authors: Denis J, Gauthier M, Rachdi L, Aubert S, Giraud-Triboult K, Poydenot P, Benchoua A, Champon B, Maury Y, Baldeschi C, Scharfmann R, Pietu G, Peschanski M, Martinat C
J Cell Sci, 2013;126(0):1763-72.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Nicotine elicits prolonged calcium signaling along ventral hippocampal axons.
Authors: Zhong C, Talmage D, Role L
PLoS ONE, 2013;8(12):e82719.
Species: Mouse
Sample Type: Whole Tissue
Application: Bioassay
Sodium phenylbutyrate enhances astrocytic neurotrophin synthesis via protein kinase C (PKC)-mediated activation of cAMP-response element-binding protein (CREB): implications for Alzheimer disease therapy.
Authors: Corbett, Grant T, Roy, Avik, Pahan, Kalipada
J Biol Chem, 2013;288(12):8299-312.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Inhibition of uterine sarcoma cell growth through suppression of endogenous tyrosine kinase B signaling.
Authors: Makino, Kenichi, Kawamura, Kazuhiro, Sato, Wataru, Kawamura, Nanami, Fujimoto, Toshio, Terada, Yukihiro
PLoS ONE, 2012;7(7):e41049.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
E-cadherin-expressing feeder cells promote neural lineage restriction of human embryonic stem cells.
Authors: Moore RN, Cherry JF, Mathur V
Stem Cells Dev., 2012;21(1):30-41.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Soluble Endoglin Specifically Binds Bone Morphogenetic Proteins 9 and 10 via Its Orphan Domain, Inhibits Blood Vessel Formation, and Suppresses Tumor Growth.
Authors: Castonguay R, Werner ED, Matthews RG, Presman E, Mulivor AW, Solban N, Sako D, Pearsall RS, Underwood KW, Seehra J, Kumar R, Grinberg AV
J. Biol. Chem., 2011;286(34):30034-46.
Species: Human
Sample Type: Recombinant Protein
Application: Surface Plasmon Resonance
Matrix-binding vascular endothelial growth factor (VEGF) isoforms guide granule cell migration in the cerebellum via VEGF receptor Flk1.
Authors: Ruiz de Almodovar C, Coulon C, Salin PA, Knevels E, Chounlamountri N, Poesen K, Hermans K, Lambrechts D, Van Geyte K, Dhondt J, Dresselaers T, Renaud J, Aragones J, Zacchigna S, Geudens I, Gall D, Stroobants S, Mutin M, Dassonville K, Storkebaum E, Jordan BF, Eriksson U, Moons L, D'Hooge R, Haigh JJ, Belin MF, Schiffmann S, Van Hecke P, Gallez B, Vinckier S, Chedotal A, Honnorat J, Thomasset N, Carmeliet P, Meissirel C
J. Neurosci., 2010;30(45):15052-66.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
EGF and bFGF pre-treatment enhances neural specification and the response to neuronal commitment of MIAMI cells.
Authors: Delcroix GJ, Curtis KM, Schiller PC, Montero-Menei CN
Differentiation, 2010;80(4):213-27.
Species: Human
Sample Type: Whole Cells
Application: Bioassay

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