抗Nav1.5抗体 | Anti-Nav1.5 antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	IHC-P analysis of rat cardiac muscle tissue using GTX54803 Nav1.5 antibody. Staining is specific for cardiomyocytes while smooth muscles cells in the artery walls are negative (red arrows). Hematoxilin is used as the counterstain.Dilution : 1:100
	WB analysis of NaV1.5 transfected HEK-293 cell lysate using GTX54803 Nav1.5 antibody preincubated with or without immunogen peptide.Dilution : 1:200

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, ICC/IF, IHC-P, FACS
Reactivity	Human, Rat

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	Assay dependent
ICC/IF	Assay dependent
IHC-P	Assay dependent
FACS	Assay dependent

Not tested in other applications.

Calculated MW	227 kDa. ( Note )
Predict Reactivity	Mouse(>80% identity)

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PROPERTIES

Form	Liquid
Buffer	PBS pH 7.4, 1% BSA, 0.05% sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	0.95 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	GST  fusion protein with amino acid residues 1978-2016 (Intracellular, C-terminus) of human NaV1.5 (Accession Q14524), (MW: 33 kDa.).
Purification	Depleted of anti-GST antibodies by affinity chromatography on immobilized GST and purified by antigen-affinity chromatography. From serum
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	sodium voltage-gated channel alpha subunit 5 , CDCD2 , CMD1E , CMPD2 , HB1 , HB2 , HBBD , HH1 , ICCD , IVF , LQT3 , Nav1.5 , PFHB1 , SSS1 , VF1
Cellular Localization	Cell membrane
Background	The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Database	・ Gene ID: 6331 SCN5A ・ UniProt: Q14524 SCN5A

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