抗CD44 [IM7]抗体 | Anti-CD44 [IM7] antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

WB analysis of HeLa cells (positive ; lane 2) and MOLT-4 (negative ; lane 1) cell lysates (non-reducing) using GTX80086 CD44 antibody [IM7].

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製品情報

Host	Rat
Clonality	Monoclonal
Clone Name	IM7
Isotype	IgG2b
Application	WB, ICC/IF, IHC-P, IHC-Fr, FACS, IP
Reactivity	Human, Mouse, Cat, Dog, Horse

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	Assay dependent
ICC/IF	Assay dependent
IHC-P	Assay dependent
IHC-Fr	Assay dependent
FACS	Assay dependent
IP	Assay dependent

Not tested in other applications.

Calculated MW	82 kDa. ( Note )
Specificity/Sensitivity	This antibody reacts with all isoforms of mouse CD44.

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PROPERTIES

Form	Liquid
Buffer	PBS, 15mM sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Mouse
Immunogen	Dexamethasone-induced cells of the SJL mouse spontaneous myeloid leukemia M1
Purification	Protein A purified
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	CD44 molecule (Indian blood group) , CDW44 , CSPG8 , ECMR-III , HCELL , HUTCH-I , IN , LHR , MC56 , MDU2 , MDU3 , MIC4 , Pgp1
Cellular Localization	Cell membrane
Background	The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
Database	・ Gene ID: 960 CD44 ・ UniProt: P16070 CD44

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Chae HK et al. VETIMM 2017; S0165-2427 (16) : 30381-6 Immunomodulatory Effects of Soluble Factors Secreted by Feline Adipose Tissue-derived Mesenchymal Stem Cells.	Application : FACS Reactivity : Cat
Lin CW et al. Acta Biomater 2016; cd44-specific nanoparticles for redox-triggered reactive oxygen species production and * release.	Application : ICC/IF, FACS Reactivity : Human, Mouse

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