抗CCR3抗体 | Anti-CCR3 antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

IHC-P analysis of human nasal mucosa tissue (allergic rhinitis) using GTX70771 CCR3 antibody.Antigen retrival : Heat-induced antigen retrieval

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	IHC-P
Reactivity	Human

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
IHC-P	8 μg/ml

Not tested in other applications.

Calculated MW	41 kDa. ( Note )
Predict Reactivity	Mouse, Rabbit, Bovine, Dog, Hamster, Monkey, Gibbon, Gorilla, Horse, Marmoset(>80% identity)

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PROPERTIES

Form	Liquid
Buffer	PBS, 0.1% sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Synthetic 16 amino acid peptide from C-terminus of human CCR3.
Purification	Purified by affinity chromatography
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	C-C motif chemokine receptor 3 , CC-CKR-3 , CD193 , CKR3 , CMKBR3
Cellular Localization	Cell membrane; Multi-pass membrane protein
Background	The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009]
Database	・ Gene ID: 1232 CCR3 ・ UniProt: P51677 CCR3

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