抗C1q抗体 | Anti-C1q antibody

• 特長
• 価格
• 製品情報
• APPLICATION
• PROPERTIES

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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製品情報

Host	Sheep
Clonality	Polyclonal
Isotype	IgG
Application	Double immunodiffusion, RID
Reactivity	Human

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
Double immunodiffusion	Assay dependent
RID	Neat-1:2
Note : RID 0.1 μl antiserum / cm² gel vs. 20 μl fresh plasma Neat-1:2

Not tested in other applications.

Specificity/Sensitivity

Gives a single arc when tested by IEP against fresh human plasma. Identity has been confirmed bydouble diffusion (Ouchterlony) against fresh human plasma and a known anti-human C1q. C1q is a sub-component of the first complement component C1, which is formed by the interaction of C1q with thetetramer C1s-C1r-C1r-C1s. C1q is a member of a family of soluble collagen-like proteins and iscomposed of three basic subunits termed A, B and C (27,550, 25,200, 23,800 Da-respectively) whichassociate in the proportion 6 A-B subunits (52,750 Da) and 3 C-C subunits (47,600 Da), to form wholeC1q (459,300 Da). C1q binds to IgG and IgM immune complexes, this activates C1r and C1s, whichare also bound to C1q and so initiates the classical pathway of complement activation. The normalplasma concentration of C1q is 100-180 mg/L.

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PROPERTIES

Form	Liquid
Buffer	Glycine Buffered Saline pH 7.4, 0.099% sodium azide, 0.1% EACA, 0.01% Benzamidine, 1 mM EDTA
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Concentration	5.07 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Human C1q, > 95% pure (SDS-PAGE). Prepared from human plasma.
Purification	IgG fraction From serum
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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