抗IKB alpha (phospho Ser32/Ser36)抗体 | Anti-IKB alpha (phospho Ser32/Ser36) antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

WB analysis of ALLN pretreated Jurkat cells left unstimulated (Lane 1, 2) or stimulated with TNF-alpha (Lane 3-7) using GTX25682 IKB alpha (phospho Ser32/Ser36) antibody.

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB
Reactivity	Human, Mouse, Pig

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	Assay dependent

Not tested in other applications.

Calculated MW	36 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	PBS pH 7.3, 1mg/ml BSA, 50% glycerol, 0.05% sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human IkBa that contains serines 32 and 36. The sequence is conserved in mouse and pig.
Purification	Purified by antigen-affinity chromatography
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	NFKB inhibitor alpha , EDAID2 , IKBA , MAD-3 , NFKBI
Cellular Localization	Cytoplasm,Nucleus
Background	This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]
Database	・ Gene ID: 4792 NFKBIA ・ UniProt: P25963 NFKBIA

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Xie MY et al. J Agric Food Chem 2019; 67 (34) : 9477-9491 Porcine Milk Exosome MiRNAs Attenuate LPS-Induced Apoptosis through Inhibiting TLR4/NF-庥B and p53 Pathways in Intestinal Epithelial Cells.	Application : WB Reactivity : Pig
Wang Z et al. Int Immunopharmacol 2019; 76 : 105873 Butylphthalide ameliorates airway inflammation and mucus hypersecretion via NF-庥B in a murine asthma model.
Wang X et al. Scand J Immunol 2019; : e12791 Epoxyeicosatrienoic acids alleviate methionine-choline-deficient diet-induced non-alcoholic steatohepatitis in mice.	Application : WB Reactivity : Mouse
Lee HM et al. Transplant Proc 2016; 48 (4) : 1226-33 Protective Effect of Eupatilin Pretreatment Against Hepatic Ischemia-Reperfusion Injury in Mice.
Cho EC et al. Mediators Inflamm 2015; 2015 : 287345 RRM2B-Mediated Regulation of Mitochondrial Activity and Inflammation under Oxidative Stress.	Application : WB Reactivity : Human

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