抗CDK4 [DCS-35]抗体 | Anti-CDK4 [DCS-35] antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

WB analysis of mouse cells using GTX23112 CDK4 antibody [DCS-35].

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製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	DCS-35
Isotype	IgG1
Application	WB, ICC/IF, IP, Functional Assay
Reactivity	Human, Mouse, Rat, Pig

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	Assay dependent
ICC/IF	Assay dependent
IP	Assay dependent
Functional Assay	Assay dependent

Not tested in other applications.

Calculated MW	34 kDa. ( Note )

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PROPERTIES

Form	Liquid
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Antigen Species	Human
Immunogen	Purified recombinant Cdk4 protein (aa 1-20)
Purification	Unpurified
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	cyclin dependent kinase 4 , CMM3 , PSK-J3
Cellular Localization	Cytoplasm,Nucleus,Membrane
Background	The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. [provided by RefSeq, Jul 2008]
Database	・ Gene ID: 1019 CDK4 ・ UniProt: P11802 CDK4

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