抗CD40L / CD154 [5F3]抗体 | Anti-CD40L / CD154 [5F3] antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

目次に戻る

価格

目次に戻る

DATA IMAGES

Flow cytometric analysis of CD154 expression on cells transfected with CD154 vector. Cells were stained with isotype control (open histogram) or CD40L (CD154) mAb (5F3) (shaded histogram).

目次に戻る

製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	5F3
Isotype	IgG1
Application	FACS
Reactivity	Human

目次に戻る

APPLICATION

Application Note

FACS: Use at a concentration of 5 - 10 μg/ml. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW	29 kDa. ( Note )

目次に戻る

PROPERTIES

Form	Liquid
Buffer	Preservative: NoneConstituents: 1% Sucrose, PBS. pH 7.2.
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Human CD40L (CD154) transfected 300-19 cell (Mouse pre-B cell line).
Purification	Protein A purified This antibody is affinity purified.
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

目次に戻る

TARGET

Synonyms	Cd40 Ligand , Cd154 , Cd40L , Higm1 , Igm , Imd3 , T-Bam , Tnfsf5 , Trap , Gp39 , Hcd40L , Cd40Lg
Cellular Localization	Type II membrane protein. Also exists as an extracellular soluble form.
Background	CD40 ligand (CD40L), also known as CD154, gp39 and TRAP, is a 33 kDa type II membrane glycoprotein expressed mainly on the cell surface of activated T lymphocytes, but also exists as a soluble form extracellularly. CD40L is the ligand for CD40, a member of the TNF superfamily, which is expressed on the cell surface of B cells, macrophages/monocytes, dendritic cells, vascular endothelial cells, and epithelial cells. CD40L plays an important role in B cell proliferation, antibody class switching, modulation of apoptosis in the germinal center through interaction with B cells expressing CD40, and activation of CD4+ T cells. Mutation within the CD40L gene is linked to hyper IgM syndrome, an X-linked immunodeficiency disease that is characterized by elevated level of serum IgM and decreased level of other isotypes.
Database	・ Gene ID: 959 ・ UniProt: P29965

目次に戻る