GDNF 組換え体(リコンビナント)タンパク質 | Recombinant Rat GDNF

掲載日情報:2015/01/26 現在Webページ番号:112965

R&D Systems社製の高品質なGDNFの組換え体タンパク質(Recombinant Rat GDNF)です。
本製品は研究用です。研究用以外には使用できません。

[在庫・価格 :2025年06月29日 00時00分現在]

※ 表示されている納期は弊社に在庫が無く、取り寄せた場合の納期目安となります。
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納期 文献数
GDNF, Rat, Recombinant <Grial Derived Neurotrophic Factor>
10日程度 ※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。 38
説明文
産生:Sf 21 (baculovirus),純度:>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.,由来動物:Rat,M.W.:15 kDa (monomer),Genbank:2668,エンドトキシンレベル:<0.01 EU per 1 µg of the protein by the LAL method.
別名:Astrocyte-derived trophic factor
Genbank No: 2668
Protein Accession No: Q07731
別包装品 別包装品あり
法規制等
保存条件 -20℃ 法規備考
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GDNF, Rat, Recombinant, Carrier-free <Grial Derived Neurotrophic Factor>
10日程度 ※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。 0
説明文
産生:Sf 21 (baculovirus),純度:>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.,由来動物:Rat,M.W.:15 kDa (monomer),Genbank:2668,エンドトキシンレベル:<0.01 EU per 1 µg of the protein by the LAL method.
別名:Astrocyte-derived trophic factor
Genbank No: 2668
Protein Accession No: Q07731
別包装品 別包装品あり
法規制等
保存条件 -20℃ 法規備考
掲載カタログ

製品記事
関連記事

[在庫・価格 :2025年06月29日 00時00分現在]

※ 表示されている納期は弊社に在庫が無く、取り寄せた場合の納期目安となります。

GDNF, Rat, Recombinant <Grial Derived Neurotrophic Factor>

文献数: 38

説明文 産生:Sf 21 (baculovirus),純度:>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.,由来動物:Rat,M.W.:15 kDa (monomer),Genbank:2668,エンドトキシンレベル:<0.01 EU per 1 µg of the protein by the LAL method.
別名:Astrocyte-derived trophic factor
Genbank No: 2668
Protein Accession No: Q07731
別包装品 別包装品あり
法規制等
保存条件 -20℃ 法規備考
掲載カタログ

製品記事
関連記事

GDNF, Rat, Recombinant, Carrier-free <Grial Derived Neurotrophic Factor>

文献数: 0

説明文 産生:Sf 21 (baculovirus),純度:>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.,由来動物:Rat,M.W.:15 kDa (monomer),Genbank:2668,エンドトキシンレベル:<0.01 EU per 1 µg of the protein by the LAL method.
別名:Astrocyte-derived trophic factor
Genbank No: 2668
Protein Accession No: Q07731
別包装品 別包装品あり
法規制等
保存条件 -20℃ 法規備考
掲載カタログ

製品記事
関連記事

バルク注文に関して

バルク包装品も承ります。お気軽にお問合せ下さい。

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CF(Carrier-Free)とは?

R&D Systems社組換え体タンパク質製品では通常ウシ血清アルブミン(BSA)をキャリアタンパク質として加えています。キャリアタンパク質を加えることで組換え体タンパク質の安定性が高まり、使用期限が長くなります。また、より濃度の低い溶液での保管も可能となります。CF製品はBSAが含まれない製品となります。一般的に細胞培養や、ELISAのスタンダードにはBSA含有製品を推奨しています。CF製品はBSAが影響してしまうアプリケーションに推奨されます。

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Product Details

Source
Spodoptera frugiperda, Sf 21 (baculovirus)-derived, Ser78-Ile211
Accession
Q07731
Structure
Disulfide-linked homodimer
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Predicted Molecular Mass
15 kDa (monomer)
Activity
Measured by its ability to support the survival and stimulate neurite outgrowth of dissociated chick embryonic dorsal root ganglia (DRG) neurons. Davies, A.M. (1989) in Neurotrophic Factor Bioassay Using Dissociated Neurons, Nerve Growth Factor. Rush, R.A. (eds)

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Additional Information

Molecule Information
GDNF
Aliases
undefined
Entrez Gene IDs
2668 (Human); 25453 (Rat)
Background
GDNF
Glial Cell Line-derived Neurotrophic Factor (GDNF) is a neurotrophic factor that has been shown to promote the survival of various neuronal subpopulations in both the central as well as the peripheral nervous systems at different stages of their development. Neuronal subpopulations that have been shown to be affected by GDNF include motoneurons, midbrain dopaminergic neurons, Purkinje cells and sympathetic neurons. Native GDNF, a disulfide-linked homodimeric glycoprotein, is a novel member of the TGF-β superfamily. Human GDNF cDNA encodes a 211 amino acid residue prepropeptide that is processed to yield a dimeric protein. Mature human GDNF was predicted to contain two 134 amino acid residue subunits. Cells known to express GDNF include Sertoli cells, type 1 astrocytes, Schwann cells, neurons, pinealocytes and skeletal muscle cells.

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Citations

Citations of cell biology reagents in peer reviewed literature can be used as a direct measure of product quality. They can also provide crucial insightinto their use under specialized or unique experimental conditions. Because of the importance published citations have to researchers, R&D Systems personnelmanually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but alsoprovides information about sample types, species, and experimental conditions.

Non-viral gene therapy for GDNF production in RCS rat: the crucial role of the plasmid dose.
Gene Ther. 2012 19:886-98
Species: N/A
Protein Application: ELISA Standard


Isolation and propagation of enteric neural crest progenitor cells from mouse embryonic stem cells and embryos.
Faial T, Gierl MS, Kawaguchi J, Nichols J, Smith A
Development 2010 137:693-704
Species: Mouse
Protein Application: Bioassay


Identification of neuregulin as a factor required for formation of aligned spermatogonia.
Chapman KM, Garbers DL, Hamra FK, Nguyen D
J. Biol. Chem. 2007 282:721-30
Species: Rat
Protein Application: Bioassay


Gdnf upregulates c-Fos transcription via the Ras/Erk1/2 pathway to promote mouse spermatogonial stem cell proliferation.
Dym M, Golestaneh N, He Z, Hofmann MC, Jiang J, Kokkinaki M
Stem Cells 2007 26:266-78
Species: Mouse
Protein Application: Bioassay


Long-term culture of male germline stem cells from hamster testes.
Chuma S, Horiuchi T, Kanatsu-Shinohara M, Lee J, Muneto T, Nakatsuji N, Shinohara T, Takenaka M
Biol. Reprod. 2007 78:611-7
Species: Hamster
Protein Application: Bioassay


Purification of bioactive glycosylated recombinant glial cell line-derived neurotrophic factor.
Ansorena E, Aymerich MS, Blanco-Prieto MJ, Garbayo E, Lanciego JL
Int J Pharm 2007 344:9-15
Species: N/A
Protein Application: Bioassay


Protective effects of neurotrophic factors on tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis of murine adrenal chromaffin cell line tsAM5D.
Hikita K, Kaneda N, Murata T, Tsuboi M
J. Biol. Chem. 2006 281:22503-16
Species: Mouse
Protein Application: Bioassay


Glial cell line-derived neurotrophic factor (GDNF) receptor alpha-1 (GFR alpha 1) is highly selective for GDNF versus artemin.
Buckley C, Carmillo P, Cate RL, Dago L, Day ES, Gronborg M, Miller S, Orozco O, Rosenblad C, Rossomando A, Sah DW, Tse A, Walus L, Whitty A, Worley DS
Biochemistry 2005 44:2545-54
Species: Rat
Protein Application: Bioassay


TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury.
Dai Y, Fukuoka T, Katsura H, Kobayashi K, Mizushima T, Noguchi K, Obata K, Tokunaga A, Tominaga M, Yamanaka H
J. Clin. Invest. 2005 115:2393-401
Species: Rat
Protein Application: In Vivo


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