BMP-2 組換え体(リコンビナント)タンパク質 | Recombinant Human BMP-2
掲載日情報:2015/01/26 現在Webページ番号:112526
R&D Systems社製の高品質なBMP-2の組換え体タンパク質(Recombinant Human BMP-2)です。
※本製品は研究用です。研究用以外には使用できません。
[在庫・価格 :2025年05月08日 10時55分現在]
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[在庫・価格 :2025年05月08日 10時55分現在]
BMP-2, Human/Mouse/Rat, Recombinant
文献数: 160
- 商品コード:355-BM-010
- メーカー:RSD
- 包装:10μg
- 価格:¥95,000
- 在庫:2個
- 納期:10日程度 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等:
説明文 | 産生:CHO,純度:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.,由来動物:Human, Mouse, Rat,M.W.:13 kDa (monomer),Genbank:650,エンドトキシンレベル:<0.10 EU per 1 µg of the protein by the LAL method. 別名:BMP2 Genbank No: 650 Protein Accession No: P12643 |
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別包装品 | 別包装品あり | ||||||
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保存条件 | -20℃ | 法規備考 | |||||
掲載カタログ |
ニュース2019年11月15日号 p.19
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関連記事 |
BMP-2, Human/Mouse/Rat, Recombinant, Carrier-free
文献数: 0
- 商品コード:355-BM-010/CF
- メーカー:RSD
- 包装:10μg
- 価格:¥95,000
- 在庫:無(未発注)
- 納期:10日程度 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等:
説明文 | 産生:CHO,純度:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.,由来動物:Human, Mouse, Rat,M.W.:13 kDa (monomer),Genbank:650,エンドトキシンレベル:<0.10 EU per 1 µg of the protein by the LAL method. 別名:BMP2 Genbank No: 650 Protein Accession No: P12643 |
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別包装品 | 別包装品あり | ||||||
法規制等 | |||||||
保存条件 | -20℃ | 法規備考 | |||||
掲載カタログ |
ニュース2019年11月15日号 p.19
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製品記事 | |||||||
関連記事 |
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バルク注文に関して
※バルク包装品も承ります。お気軽にお問合せ下さい。
追加しました。
CF(Carrier-Free)とは?
R&D Systems社組換え体タンパク質製品では通常ウシ血清アルブミン(BSA)をキャリアタンパク質として加えています。キャリアタンパク質を加えることで組換え体タンパク質の安定性が高まり、使用期限が長くなります。また、より濃度の低い溶液での保管も可能となります。CF製品はBSAが含まれない製品となります。一般的に細胞培養や、ELISAのスタンダードにはBSA含有製品を推奨しています。CF製品はBSAが影響してしまうアプリケーションに推奨されます。
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Product Details
- Source
- Chinese Hamster Ovary cell line, CHO-derived, Gln283-Arg396
- Accession
- P12643
- Structure
- Disulfide-linked homodimer
- Purity
- >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
- Predicted Molecular Mass
- 13 kDa (monomer)
- SDS-PAGE
- 15-16 kDa, reducing conditions
- Activity
- Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Binnerts, M.E. et al. (2004) Biochem. Biophys. Res. Commun. 315(2)
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Additional Information
- Molecule Information
- BMP-2
- Aliases
- undefined
- Entrez Gene IDs
- 650 (Human); 12156 (Mouse); 29373 (Rat)
- Background
- BMPs (Bone Morphogenetic Proteins)
- BMPs are secreted signaling molecules that comprise a subfamily of the TGF-beta superfamily and were originally identified as regulators of cartilage and bone formation. There are at least 20 structurally and functionally related BMPs, most of which play roles in embryogenesis and morphogenesis of various tissues and organs. Biologically active BMPs are usually homodimers containing a characteristic cysteine knot structure. Heterodimers, BMP-2/BMP-7 and BMP-4/BMP-7 have also been suggested to exist and function in vivo. They are more potent inducers of bone formation than their respective homodimers. In addition, heterodimers, but not homodimers, are ventral mesoderm inducers. Heterodimer activity may be mediated by a different or additional receptor subtype.Decapentaplegic (Dpp) is one of at least five TGF-beta superfamily ligands identified in the Drosophila genome. Dpp, a functional ortholog of mammalian BMP-2 and BMP-4, is a morphogen and plays an essential role in Drosophila development. Dpp regulates embryonic dorsal-ventral polarity and is required for gut morphogenesis and outgrowth and patterning of imaginal disks.
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Citations
Citations of cell biology reagents in peer reviewed literature can be used as a direct measure of product quality. They can also provide crucial insightinto their use under specialized or unique experimental conditions. Because of the importance published citations have to researchers, R&D Systems personnelmanually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but alsoprovides information about sample types, species, and experimental conditions.
H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs.
Chen , Jiekai, Chen , Jing, Chen , Shen, Chen , You, Guo , Lin, Li , Dongwei, Li , Xuejia, Liang , Hanquan, Liu , He, Liu , Jing, Pei , Duanqing, Peng , Tianran, Qi , Jing, Wang , Tao, Wei , Bei, Wu , Yaran, Yang , Jiaqi, Zhang , Yixin, Zhao , Xiangjie, Zhu , Jieying
Nat Genet 2013 45:34-42
Species: Mouse
Protein Application: Bioassay
Generation of robust vascular networks from cardiovascular blast populations derived from human induced pluripotent stem cells in vivo and ex vivo organ culture system.
Kawamoto T, Kobayashi Y, Nakajima H, Yamagishi Y
Biochem Biophys Res Commun 2013 441:180-5
Species: Mouse
Protein Application: Bioassay
Gremlin-1 induces BMP-independent tumor cell proliferation, migration, and invasion.
Kim M, Lee S, Yoon S
PLoS ONE 2012 7:e35100
Species: Human
Protein Application: Binding Assay
Repulsive guidance molecule (RGM) family proteins exhibit differential binding kinetics for bone morphogenetic proteins (BMPs).
Babitt , Jodie L, Lin , Herbert , Sun , Chia Chi, Wu , Qifang
PLoS ONE 2012 7:e46307
Species: Human
Protein Application: Surface Plasmon Resonance
Osteoblast-like differentiation of cultured human coronary artery smooth muscle cells by bone morphogenetic protein endothelial cell precursor-derived regulator (BMPER).
Asada Y, Emoto N, Hatakeyama K, Hirata K, Ishida T, Kinugasa M, Kobayashi R, Kurogane Y, Rikitake Y, Satomi-Kobayashi S, Takai Y
J Biol Chem 2012 287:30336-45
Protein phosphatase 5 modulates SMAD3 function in the transforming growth factor-beta pathway.
Bruce D, Macartney T, Sapkota G, Shou W, Yong W
Cell Signal 2012 24:1999-2006
Sertoli cell-conditioned medium induces germ cell differentiation in human embryonic stem cells.
Geens M, Sermon KD
J. Assist. Reprod. Genet. 2011 0:
Species: Human
Protein Application: Bioassay
Soluble Endoglin Specifically Binds Bone Morphogenetic Proteins 9 and 10 via Its Orphan Domain, Inhibits Blood Vessel Formation, and Suppresses Tumor Growth.
Castonguay R, Grinberg AV, Kumar R, Matthews RG, Mulivor AW, Pearsall RS, Presman E, Sako D, Seehra J, Solban N, Underwood KW, Werner ED
J. Biol. Chem. 2011 286:30034-46
Species: Human
Protein Application: Surface Plasmon Resonance
Age-related changes in rat bone-marrow mesenchymal stem cell plasticity.
Asumda FZ, Chase PB
BMC Cell Biol. 2011 12:44
Species: Rat
Protein Application: Bioassay
Bone morphogenetic protein-2 may represent the molecular link between oxidative stress and vascular stiffness in chronic kidney disease.
Balestra C, Cosola C, Dalfino G, Grandaliano G, Manno C, Pertosa G, Porreca S, Schena FP, Simone S
Atherosclerosis 2010 211:418-23
Species: Human
Protein Application: Bioassay
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