アンフィレグリン（ヒト、組換え体タンパク質） Amphiregulin（AREG, Human, Recombinant）

R&D Systems社製の高品質なAmphiregulinの組換え体タンパク質(Recombinant Human Amphiregulin)です。

※ Amphiregulin ELISA Kitについては、こちらの記事をご覧下さい。

R&D Systems社組換え体タンパク質製品では通常ウシ血清アルブミン(BSA)をキャリアタンパク質として加えています。キャリアタンパク質を加えることで組換え体タンパク質の安定性が高まり、使用期限が長くなります。また、より濃度の低い溶液での保管も可能となります。CF製品はBSAが含まれない製品となります。一般的に細胞培養や、ELISAのスタンダードにはBSA含有製品を推奨しています。CF製品はBSAが影響してしまうアプリケーションに推奨されます。

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Citations of cell biology reagents in peer reviewed literature can be used as a direct measure of product quality. They can also provide crucial insightinto their use under specialized or unique experimental conditions. Because of the importance published citations have to researchers, R&D Systems personnelmanually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but alsoprovides information about sample types, species, and experimental conditions.

Cardiac macrophages prevent sudden death during heart stress.
Sugita J, Fujiu K, Nakayama Y, Matsubara T, Matsuda J, Oshima T, Liu Y, Maru Y, Hasumi E, KojimaT, Seno H, Asano K, Ishijima A,Tomii N, Yamazaki M, Kudo F, Sakuma I, Nagai R, Manabe I, Komuro I
Nat. Commun. 2021 12(1):1910
Species: Human
Protein Application: Bioassay


The Q43L mutant of neuregulin 2beta is a pan-ErbB receptor antagonist.
Cameron EM, Gallo RM, Mill CP, Riese DJ, Settleman J, VanBrocklin H, Wilson KJ
Biochem. J. 2012 443:133-44
Species: Human
Protein Application: Bioassay


The EGFR ligands amphiregulin and heparin-binding egf-like growth factor promote peritoneal carcinomatosis in CXCR4-expressing gastric cancer.
Donev IS, Kawashima A, Li Q, Mouri H, Ohtsubo K, Tacheuchi S, Wang W, Yamada T, Yamashita K, Yano S, Yasumoto K
Clin. Cancer Res. 2011 17:3619-30
Species: Human
Protein Application: Bioassay


Non-canonical HIF-2alpha function drives autonomous breast cancer cell growth via an AREG-EGFR/ErbB4 autocrine loop.
Abreu-Rodriguez I, Bordoli MR, Gradin K, Kristiansen G, Poellinger L, Schraml P, Stiehl DP, Wenger RH, Wollenick K
Oncogene 2011 0:
Species: Human
Protein Application: Bioassay


Amphiregulin carboxy-terminal domain is required for autocrine keratinocyte growth.
Elder JT, Johnson JL, Li Y, Rittie L, Stoll SW
J. Invest. Dermatol. 2010 130:2031-40
Species: Human
Protein Application: Bioassay


Development and validation of sandwich ELISA microarrays with minimal assay interference.
Crowley SA, Gonzalez RM, Seurynck-Servoss SL
J. Proteome Res. 2008 7:2406-14
Species: N/A
Protein Application: ELISA Standard


Epidermal growth factor-like growth factors prevent apoptosis of alcohol-exposed human placental cytotrophoblast cells.
Armant DR, Chiang PJ, Romero R, Smith SM, Wolff GS
Biol. Reprod. 2007 77:53-60
Species: Human
Protein Application: Bioassay


EGF-like ligands stimulate osteoclastogenesis by regulating expression of osteoclast regulatory factors by osteoblasts: implications for osteolytic bone metastases.
Jia X, Kang Y, Partridge NC, Qin L, Xiao G, Zhu J
J. Biol. Chem. 2007 282:26656-64
Species: Mouse
Protein Application: Bioassay


Human trophoblast survival at low oxygen concentrations requires metalloproteinase-mediated shedding of heparin-binding EGF-like growth factor.
Armant DR, Duniec-Dmuchowski ZM, Edwards HJ, Edwin SS, Kilburn BA, Leach RE, Petkova A, Romero R
Development 2006 133:751-9
Species: Human
Protein Application: Bioassay


Cigarette smoke synergistically enhances respiratory mucin induction by proinflammatory stimuli.
Baginski TK, Dabbagh K, Satjawatcharaphong C, Swinney DC
Am. J. Respir. Cell Mol. Biol. 2006 35:165-74
Species: Human
Protein Application: Bioassay


Autocrine extracellular signal-regulated kinase (ERK) activation in normal human keratinocytes: metalloproteinase-mediated release of amphiregulin triggers signaling from ErbB1 to ERK.
Johnson JL, Kansra S
Mol. Biol. Cell 2004 15:4299-309
Species: Human
Protein Application: Bioassay