KGF/FGF-7 組換え体(リコンビナント)タンパク質 | Recombinant Human KGF/FGF-7
掲載日情報：2015/01/26 現在Webページ番号：112146
R&D Systems社製の高品質なKGF/FGF-7の組換え体タンパク質(Recombinant Human KGF/FGF-7)です。
※本製品は研究用です。研究用以外には使用できません。
[在庫・価格 ：2025年07月04日 14時15分現在]
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FGF-7, Human, Recombinant <KGF> |
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FGF-7, Human, Recombinant, Carrier-free <KGF> |
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[在庫・価格 ：2025年07月04日 14時15分現在]
FGF-7, Human, Recombinant <KGF>
文献数： 39
- 商品コード：251-KG-010
- メーカー：RSD
- 包装：10μg
- 価格：¥57,000
- 在庫：2個
- 納期：10日程度 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等：
| 説明文 | 産生：E. coli，純度：>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.，由来動物：Human，M.W.：19 kDa，Genbank：2252，エンドトキシンレベル：<0.10 EU per 1 µg of the protein by the LAL method. 別名：FGF7 Genbank No： 2252 Protein Accession No： P21781 |
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| 保存条件 | -20℃ | 法規備考 | |||||
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| 関連記事 | R&D Systems 製品WHO Unit Conversion Table |
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FGF-7, Human, Recombinant, Carrier-free <KGF>
文献数： 0
- 商品コード：251-KG-010/CF
- メーカー：RSD
- 包装：10μg
- 価格：¥57,000
- 在庫：1個
- 納期：10日程度 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等：
| 説明文 | 産生：E. coli，純度：>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by CoomassieR Blue Staining.，由来動物：Human，M.W.：19 kDa，Genbank：2252，エンドトキシンレベル：<0.10 EU per 1 μg of the protein by the LAL method. 別名：FGF7 Genbank No： 2252 Protein Accession No： P21781 |
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| 別包装品 | 別包装品あり | ||||||
| 法規制等 | |||||||
| 保存条件 | -20℃ | 法規備考 | |||||
| 掲載カタログ |
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| 製品記事 | |||||||
| 関連記事 | R&D Systems 製品WHO Unit Conversion Table |
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バルク注文に関して
※バルク包装品も承ります。お気軽にお問合せ下さい。
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CF(Carrier-Free)とは？
R&D Systems社組換え体タンパク質製品では通常ウシ血清アルブミン(BSA)をキャリアタンパク質として加えています。キャリアタンパク質を加えることで組換え体タンパク質の安定性が高まり、使用期限が長くなります。また、より濃度の低い溶液での保管も可能となります。CF製品はBSAが含まれない製品となります。一般的に細胞培養や、ELISAのスタンダードにはBSA含有製品を推奨しています。CF製品はBSAが影響してしまうアプリケーションに推奨されます。
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Product Details
- Source
- E. coli-derived, Cys32-Thr194, with an N-terminal Met
- Accession
- Q6FGV5
- Purity
- >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
- Predicted Molecular Mass
- 19 kDa
- Activity
- Measured in a cell proliferation assay using 4MBr‑5 rhesus monkey epithelial cells. Rubin, J.S. et al. (1989) Proc. Natl. Acad. Sci. USA 86
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Additional Information
- Molecule Information
- KGF/FGF-7
- Aliases
- FGF7; FGF-7
- Entrez Gene IDs
- 2252 (Human); 403915 (Canine)
- Background
- KGF/FGF-7
- The FGF family is comprised of at least nine polypeptides that show a variety of biological activities toward cells of mesenchymal, neuronal and epithelial origin. All FGFs have two conserved cysteine residues and share 30 - 50% sequence identity at the amino acid level. KGF/FGF-7 was originally isolated from the conditioned medium of a human embryonic lung fibroblast cell line as a mitogen that is specific for epithelial cells. The transcript for KGF/FGF-7 can be detected in stromal but not epithelial cells from various epithelial tissues. It has been proposed that KGF is a mesenchymal cell-derived paracrine growth factor that specifically stimulates epithelial cell growth.The KGF cDNA encodes a 194 amino acid precursor protein from which the N-terminal 31 amino acid residues are cleaved to generate the mature KGF. Human KGF exhibits species cross-reactivity and is active on mouse, monkey, and porcine cells. A high affinity receptor for KGF has been cloned and shown to be an alternatively spliced isoform of FGF R2/bek. Whereas FGF R2 binds FGF acidic and FGF basic but not KGF with high affinity, the alternately spliced KGF/FGF-7 R can bind KGF and FGF acidic with high affinity.
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Citations
Citations of cell biology reagents in peer reviewed literature can be used as a direct measure of product quality. They can also provide crucial insightinto their use under specialized or unique experimental conditions. Because of the importance published citations have to researchers, R&D Systems personnelmanually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but alsoprovides information about sample types, species, and experimental conditions.
Generation of glucose-responsive, insulin-producing cells from human umbilical cord blood-derived mesenchymal stem cells.
Dominguez-Bendala J, Inverardi L, Molano R, Pileggi A, Prabakar K, Ricordi C, Villate S
Cell Transplant 2012 21:1321-39
Species: Human
Protein Application: cell culture
Altered splicing of FGFR1 is associated with high tumor grade and stage and leads to increased sensitivity to FGF1 in bladder cancer.
Knowles MA, Tomlinson DC
Am. J. Pathol. 2010 177:2379-86
Species: Human
Protein Application: Bioassay
Specific heparan sulfate structures modulate FGF10-mediated submandibular gland epithelial morphogenesis and differentiation.
Cowherd SN, Hoffman MP, Lassiter KS, Likar KM, Patel VN, Ron D, Sher I, Turnbull JE, Yates EA, Zisman-Rozen S
J. Biol. Chem. 2008 283:9308-17
Species: Mouse
Protein Application: Bioassay
Platelet-derived growth factor receptor regulates salivary gland morphogenesis via fibroblast growth factor expression.
Aizawa S, Arakaki M, Chai Y, Fukumoto E, Fukumoto S, Iwamoto T, Nonaka K, Oka K, Suzuki H, Tanaka K, Yamada A, Yamamoto S, Yoshizaki K, Yuasa K
J. Biol. Chem. 2008 283:23139-49
Species: Mouse
Protein Application: Bioassay
Neuritogenic activity of chondroitin/dermatan sulfate hybrid chains of embryonic pig brain and their mimicry from shark liver. Involvement of the pleiotrophin and hepatocyte growth factor signaling pathways.
Li F, Shetty AK, Sugahara K
J. Biol. Chem. 2007 282:2956-66
Species: Fish - P. glauca (blue shark)
Protein Application: Bioassay
Differentiated human alveolar epithelial cells and reversibility of their phenotype in vitro.
Chang Y, Chen X, Cosgrove GP, Edeen K, Fang X, Funk CJ, Manzer R, Mason RJ, Wang J, Wang S
Am. J. Respir. Cell Mol. Biol. 2007 36:661-8
Species: Human
Protein Application: Bioassay
Heparanase cleavage of perlecan heparan sulfate modulates FGF10 activity during ex vivo submandibular gland branching morphogenesis.
Eftekhari S, Elkin M, Hoffman MP, Hossain R, Knox SM, Lathrop CA, Likar KM, Patel VN, Vlodavsky I, Whitelock JM
Development 2007 134:4177-86
Species: Mouse
Protein Application: Bioassay
The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis.
Sa SM, Valdez PA, Wu J
J. Immunol. 2007 178:2229-40
Species: Human
Protein Application: Bioassay
FGF2 posttranscriptionally down-regulates expression of SDF1 in bone marrow stromal cells through FGFR1 IIIc.
Mutsuga N, Nakayama T, Tosato G
Blood 2006 109:1363-72
Species: Mouse
Protein Application: Bioassay
Development of an in vitro pancreatic tissue model to study regulation of islet neogenesis associated protein expression.
Makhlin J, Petropavlovskaia M, Rosenberg L, Sampalis J
J. Endocrinol. 2006 191:65-81
Species: Hamster
Protein Application: Bioassay
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