抗Integrin alpha 7抗体 | Anti-Integrin alpha 7 Antibody

• Bioss 社抗体製品の特長
• 価格表
• 使用例
• Background
• 製品情報

Bioss 社抗体製品の特長

• ウエスタンブロット、免疫組織化学（IHC-frozen、IHC-paraffin）、免疫蛍光（IF）、ELISAなどのアプリケーションに適した一次抗体がラインナップされています。
• 一次抗体はすべて、Protein AまたはProtein G精製されています。
• 幅広い研究分野に関連する抗体を取り揃えています。


※最新の適用、交差性情報の詳細は、下記製品情報項の「データシート」リンクをご参照ください。

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価格表

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使用例

	Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-Integrin alpha 7/ITGA7 Polyclonal Antibody, Unconjugated (bs-1816R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.
	Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti- Integrin alpha 7/ITGA7 Polyclonal Antibody, Unconjugated (bs-1816R) at 1:200 followed by conjugation to the secondary antibody Goat Anti-Rabbit IgG, Cy3 conjugated (bs-0295G-Cy3) used at 1:200 dilution for 40 minutes at 37°C
	Paraformaldehyde-fixed, paraffin embedded rat skeletal muscle; Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (normal goat serum) at 37°C for 20min; Antibody incubation with \r\nIntegrin alpha 7 Polyclonal Antibody, Unconjugated (bs-1816R) at 1:200 overnight at 4°C, followed by a conjugated secondary and DAB staining.

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Background

Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.

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製品情報

name	Integrin alpha 7 Polyclonal Antibody
datasheet	最新のデータシートはこちらをご確認ください
Conjugation	Unconjugated
Immunogen Range	730-780/1181
Gene ID	3679
Swiss Prot	Q13683
Source	KLH conjugated synthetic peptide derived from human Integrin alpha 7
Purification	Purified by Protein A.
Synonyms	Integrin alpha-7; ITGA7; UNQ46/PRO768

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