抗α-Smooth Muscle Actin抗体(Anti-α-Smooth Muscle Actin, Human, Mouse-Mono, PE antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information
• Citations

価格

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Product Details

Species Reactivity	Human
Label	Phycoerythrin
Immunogen	alpha -Smooth Muscle Actin N-terminal Synthetic Decapeptide
Source	Monoclonal Mouse IgG2A Clone # 1A4
Purification	Protein A or G purified from hybridoma culture supernatant
Specificity	Detects human  alpha -Smooth Muscle Actin.

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Applications and Data

	Recommended Concentration	Sample
Intracellular Staining by Flow Cytometry	10 µL/106 cells	See below

Intracellular Staining by Flow Cytometry

Detection of alpha ‑Smooth Muscle Actin in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Mouse Anti-Human alpha ‑Smooth Muscle Actin PE‑conjugated Monoclonal Antibody (Catalog # IC1420P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (Catalog # FC004) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I (Catalog # FC005). View our protocol for Staining Intracellular Molecules.

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Related Product & Information

Background	alpha-Smooth Muscle Actin
background_content	Background: alpha-Smooth Muscle Actin alpha ‑Smooth Muscle Actin has been frequently used as a marker of smooth muscle differentiation (1, 2).

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Citations

1. Attenuated PDGF signaling drives alveolar and microvascular defects in neonatal chronic lung�disease
   Authors: P Oak, T Pritzke, I Thiel, M Koschlig, DS Mous, A Windhorst, N Jain, O Eickelberg, K Foerster, A Schulze, W Goepel, T Reicherzer, H Ehrhardt, RJ Rottier, P Ahnert, L Gortner, TJ Desai, A Hilgendorf
   EMBO Mol Med, 2017;0(0):.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow


2. Reduced suppressive effect of ?2-adrenoceptor agonist on fibrocyte function in severe asthma
   Authors: CY Lo, C Michaeloud, PK Bhavsar, CD Huang, PJ Chang, CH Wang, HP Kuo, KF Chung
   Respir. Res., 2017;18(1):194.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


3. Glucose transporter 1-positive endothelial cells in infantile hemangioma exhibit features of facultative stem cells.
   Authors: Huang L, Nakayama H, Klagsbrun M, Mulliken J, Bischoff J
   Stem Cells, 2015;33(1):133-45.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


4. MicroRNA 181b regulates decorin production by dermal fibroblasts and may be a potential therapy for hypertrophic scar.
   Authors: Kwan P, Ding J, Tredget E
   PLoS ONE, 2015;10(4):e0123054.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


5. Natural killer cell-dependent anti-fibrotic pathway in liver injury via Toll-like receptor-9.
   Authors: Abu-Tair L, Axelrod J, Doron S, Ovadya Y, Krizhanovsky V, Galun E, Amer J, Safadi R
   PLoS ONE, 2013;8(12):e82571.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


6. Loss of endogenous bone morphogenetic protein-6 aggravates renal fibrosis.
   Authors: Dendooven A, van Oostrom O, van der Giezen DM, Leeuwis JW, Snijckers C, Joles JA, Robertson EJ, Verhaar MC, Nguyen TQ, Goldschmeding R
   Am. J. Pathol., 2011;178(3):1069-79.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


7. Circulating angiogenic precursors in idiopathic pulmonary arterial hypertension.
   Authors: Asosingh K, Aldred MA, Vasanji A, Drazba J, Sharp J, Farver C, Comhair SA, Xu W, Licina L, Huang L, Anand-Apte B, Yoder MC, Tuder RM, Erzurum SC
   Am. J. Pathol., 2008;172(3):615-27.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


8. Characterization of human lung tumor-associated fibroblasts and their ability to modulate the activation of tumor-associated T cells.
   Authors: Nazareth MR, Broderick L, Simpson-Abelson MR, Kelleher RJ, Yokota SJ, Bankert RB
   J. Immunol., 2007;178(9):5552-62.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow

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