抗Human/Mouse SOX2 Phycoerythrin抗体(Anti-Human/Mouse SOX2 Phycoerythrin antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information
• Citations

価格

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Product Details

Species Reactivity	Human, Mouse
Label	Phycoerythrin
Immunogen	E. coli-derived recombinant human SOX2Gly135-Met317Accession # P48431
Source	Monoclonal Mouse IgG2A Clone # 245610
Purification	Protein A or G purified from hybridoma culture supernatant
Specificity	Detects human and mouse SOX2 in Western blots.

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Applications and Data

	Recommended Concentration	Sample
Intracellular Staining by Flow Cytometry	10 µL/106 cells	See below

Intracellular Staining by Flow Cytometry

Detection of SOX2 in NTera‑2 Human Cell Line by Flow Cytometry. NTera‑2 human testicular embryonic carcinoma cell line was stained with Mouse Anti-Human/Mouse SOX2 PE‑conjugated Monoclonal Antibody (Catalog # IC2018P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (Catalog # FC004) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I (Catalog # FC005). View our protocol for Staining Intracellular Molecules.

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Related Product & Information

Background	SOX2
background_content	Background: SOX2 SOX2 belongs to the SOX (SRY-like HMG box) family of transcription factors with diverse roles in development. SOX2 functions in specifying the first three lineages present at implantation and in regulating proliferation and differentiation in the developing peripheral nervous system (1-6).

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Citations

1. Generation of human erythroblast-derived iPSC line using episomal reprogramming system
   Authors: E Varga, M Hansen, T Wüst, M von Linder, E van den Ak
   Stem Cell Res, 2017;25(0):30-33.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


2. Generation of human induced pluripotent stem cells (EURACi001-A, EURACi002-A, EURACi003-A) from peripheral blood mononuclear cells of three patients carrying mutations in the CAV3 gene
   Authors: V Meraviglia, P Benzoni, S Landi, C Murano, M Langione, BM Motta, S Baratto, R Silipigni, M Di Segni, PP Pramstalle, D DiFrancesc, E Gazzerro, A Barbuti, A Rossini
   Stem Cell Res, 2017;27(0):25-29.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


3. Mitochondrial role in adaptive response to stress conditions in preeclampsia
   Sci Rep, 2016;6(0):32410.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


4. A single-cell and feeder-free culture system for monkey embryonic stem cells.
   Authors: Ono T, Suzuki Y, Kato Y, Fujita R, Araki T, Yamashita T, Kato H, Torii R, Sato N
   PLoS ONE, 2014;9(2):e88346.
   Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
   Sample Type: Whole Cells
   Application: Flow


5. Patients with multiple myeloma develop SOX2-specific autoantibodies after allogeneic stem cell transplantation.
   Authors: Kobold S, Tams S, Luetkens T, Cao Y, Sezer O, Bartels B, Reinhard H, Templin J, Bartels K, Hildebrandt Y, Lajmi N, Marx A, Haag F, Bokemeyer C, Kroger N, Atanackovic D
   Clin Dev Immunol, 2011;2011(0):302145.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow

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