抗SOX2 [SOX2/1791]抗体 | Anti-SOX2 [SOX2/1791] antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	IHC-P analysis of mouse intestine tissue using GTX35086 SOX2 antibody [SOX2/1791].
	IHC-P analysis of mouse stomach tissue using GTX35086 SOX2 antibody [SOX2/1791].
	IHC-P analysis of mouse brain tissue using GTX35086 SOX2 antibody [SOX2/1791].
	WB analysis of recombinant SOX2 protein fragment and NCCIT cell lysates using GTX35086 SOX2 antibody [SOX2/1791].
	IHC-P analysis of human cervical carcinoma tissue using GTX35086 SOX2 antibody [SOX2/1791].
	IHC-P analysis of human lung carcinoma tissue using GTX35086 SOX2 antibody [SOX2/1791].
	WB analysis of A549 cell lysate using GTX35086 SOX2 antibody [SOX2/1791].
	Analysis of Protein Array containing more than 19,000 full-length human proteins using SOX2 Mouse Monoclonal Antibody (SOX2/1791). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.

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製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	SOX2/1791
Isotype	IgG2b
Application	WB, IHC-P, ELISA, Protein Array
Reactivity	Human, Mouse

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	1-2μg/ml
IHC-P	1-2μg/ml for 30 min at RT
ELISA	2-4μg/ml (for coating)
Protein Array	Assay dependent
Note : IHC-P Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes. ELISA For ELISA coating, recommend using BSA-free format (please contact us for PBS only format).

Not tested in other applications.

Calculated MW	34 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	10mM PBS, 0.05% BSA, 0.05% sodium azide (Please contact us for PBS only format)
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	0.2 mg/ml
Antigen Species	Human
Immunogen	Recombinant fragment (within aa176-305) of human SOX2 protein (exact sequence is proprietary)
Purification	Protein A/G purified
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	ANOP3,MCOPS3,SOX2,SRYbox 2,SRY-box transcription factor 2
Cellular Localization	Nucleus
Background	This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008]
Database	・ Gene ID: 6657 SOX2 ・ UniProt: P48431 SOX2

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