Recombinant 組換え体(リコンビナント)タンパク質 | Ubiquitin, Human, Recombinant
掲載日情報：2018/02/08 現在Webページ番号：216429
R&D Systems社製の高品質なRecombinantの組換え体タンパク質(Ubiquitin, Human, Recombinant)です。
※本製品は研究用です。研究用以外には使用できません。
[在庫・価格 ：2024年05月03日 14時35分現在]
※ 表示されている納期は弊社に在庫が無く、取り寄せた場合の納期目安となります。
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[在庫・価格 ：2024年05月03日 14時35分現在]
※ 表示されている納期は弊社に在庫が無く、取り寄せた場合の納期目安となります。
Ubiquitin, Human, Recombinant, Carrier-free
文献数： 0
- 商品コード：U-100H-10M
- メーカー：RSD
- 包装：10mg
- 価格：¥28,000
- 在庫：1個
- 納期：10日程度 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等：
| 説明文 |
M.W.：8.6 kDa，純度：>95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain.，形状：凍結乾燥品，ブランド：Boston Biochem，由来動物：Human，Genbank：6233，産生：E. coli 別名：RPS27A Genbank No： 6233 Protein Accession No： P0CG47 |
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| 保存条件 | -20℃ | 法規備考 | |
| 掲載カタログ |
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| 製品記事 |
各種モノユビキチン ユビキチン・プロテアソーム特集 |
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CF(Carrier-Free)とは？
R&D Systems社組換え体タンパク質製品では通常ウシ血清アルブミン(BSA)をキャリアタンパク質として加えています。キャリアタンパク質を加えることで組換え体タンパク質の安定性が高まり、使用期限が長くなります。また、より濃度の低い溶液での保管も可能となります。CF製品はBSAが含まれない製品となります。一般的に細胞培養や、ELISAのスタンダードにはBSA含有製品を推奨しています。CF製品はBSAが影響してしまうアプリケーションに推奨されます。
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Product Details
- Purity
- >95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain
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Related Product & Information
- Background
- Ubiquitin
- Ubiquitin is a 76 amino acid (aa) protein that is ubiquitously expressed in all eukaryotic organisms. Ubiquitin is highly conserved with 96% aa sequence identity shared between human and yeast Ubiquitin, and 100% aa sequence identity shared between human and mouse Ubiquitin (1). In mammals, four Ubiquitin genes encode for two Ubiquitin-ribosomal fusion proteins and two poly-Ubiquitin proteins. Cleavage of the Ubiquitin precursors by deubiquitinating enzymes gives rise to identical Ubiquitin monomers each with a predicted molecular weight of 8.6 kDa. Conjugation of Ubiquitin to target proteins involves the formation of an isopeptide bond between the C-terminal glycine residue of Ubiquitin and a lysine residue in the target protein. This process of conjugation, referred to as ubiquitination or ubiquitylation, is a multi-step process that requires three enzymes: a Ubiquitin-activating (E1) enzyme, a Ubiquitin-conjugating (E2) enzyme, and a Ubiquitin ligase (E3). Ubiquitination is classically recognized as a mechanism to target proteins for degradation and as a result, Ubiquitin was originally named ATP-dependent Proteolysis Factor 1 (APF-1) (2,3). In addition to protein degradation, ubiquitination has been shown to mediate a variety of biological processes such as signal transduction, endocytosis, and post-endocytic sorting (4-7). Highly purified Ubiquitin processed for the quantitative removal of glycine and buffer salts which can interfere with chemical and in vitro reactions.
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Citations
R&D Systems personnel manually curate a database that contains references using R&D Systems products.
The data collected includes not only links to publications in PubMed,
but also provides information about sample types, species, and experimental conditions.
The data collected includes not only links to publications in PubMed,
but also provides information about sample types, species, and experimental conditions.
Inhibition of the deubiquitinase USP5 leads to c-Maf protein degradation and myeloma cell apoptosis
Authors: S Wang, J Juan, Z Zhang, Y Du, Y Xu, J Tong, B Cao, MF Moran, Y Zeng, X Mao
Cell Death Dis, 2017;8(9):e3058.
Species: Human
Sample Type: Recombinant Protein
Application: Ubiquination
Authors: S Wang, J Juan, Z Zhang, Y Du, Y Xu, J Tong, B Cao, MF Moran, Y Zeng, X Mao
Cell Death Dis, 2017;8(9):e3058.
Species: Human
Sample Type: Recombinant Protein
Application: Ubiquination
An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons
Authors: M Boselli, BH Lee, J Robert, MA Prado, SW Min, C Cheng, MC Silva, C Seong, S Elsasser, KM Hatle, TC Gahman, SP Gygi, SJ Haggarty, L Gan, RW King, D Finley
J. Biol. Chem., 2017;0(0):.
Species: Human
Sample Type: Purified Proteins
Application: EnzAct
Authors: M Boselli, BH Lee, J Robert, MA Prado, SW Min, C Cheng, MC Silva, C Seong, S Elsasser, KM Hatle, TC Gahman, SP Gygi, SJ Haggarty, L Gan, RW King, D Finley
J. Biol. Chem., 2017;0(0):.
Species: Human
Sample Type: Purified Proteins
Application: EnzAct
Plk1 phosphorylation of CAP-H2 triggers chromosome condensation by condensin II at the early phase of mitosis
Authors: Y Kagami, M Ono, K Yoshida
Sci Rep, 2017;7(1):5583.
Species: Human
Sample Type: Recombinant Proteins
Application: Bioassay
Authors: Y Kagami, M Ono, K Yoshida
Sci Rep, 2017;7(1):5583.
Species: Human
Sample Type: Recombinant Proteins
Application: Bioassay
pSILAC mass spectrometry reveals ZFP91 as IMiD-dependent substrate of the CRL4(CRBN) ubiquitin ligase
Authors: J An, CM Ponthier, R Sack, J Seebacher, MB Stadler, KA Donovan, ES Fischer
Nat Commun, 2017;8(0):15398.
Species: N/A
Sample Type: Proteins
Application: Bioassay
Authors: J An, CM Ponthier, R Sack, J Seebacher, MB Stadler, KA Donovan, ES Fischer
Nat Commun, 2017;8(0):15398.
Species: N/A
Sample Type: Proteins
Application: Bioassay
BAP1 regulates IP3R3-mediated Ca(2+) flux to mitochondria suppressing cell transformation
Authors: A Bononi, C Giorgi, S Patergnani, D Larson, K Verbruggen, M Tanji, L Pellegrini, V Signorato, F Olivetto, S Pastorino, M Nasu, A Napolitano, G Gaudino, P Morris, G Sakamoto, LK Ferris, A Danese, A Raimondi, C Tacchetti, S Kuchay, HI Pass, EB Affar, H Yang, P Pinton, M Carbone
Nature, 2017;546(7659):549-553.
Species: N/A
Sample Type: Protein
Application: Bioassay
Authors: A Bononi, C Giorgi, S Patergnani, D Larson, K Verbruggen, M Tanji, L Pellegrini, V Signorato, F Olivetto, S Pastorino, M Nasu, A Napolitano, G Gaudino, P Morris, G Sakamoto, LK Ferris, A Danese, A Raimondi, C Tacchetti, S Kuchay, HI Pass, EB Affar, H Yang, P Pinton, M Carbone
Nature, 2017;546(7659):549-553.
Species: N/A
Sample Type: Protein
Application: Bioassay
DNA damage and S phase-dependent E2F1 stabilization requires the cIAP1 E3-ubiquitin ligase and is associated with K63-poly-ubiquitination on lysine 161/164 residues
Authors: V Glorian, J Allègre, J Berthelet, B Dumetier, PM Boutanquoi, N Droin, C Kayaci, J Cartier, S Gemble, G Marcion, D Gonzalez, R Boidot, C Garrido, O Michaud, E Solary, L Dubrez
Cell Death Dis, 2017;8(5):e2816.
Species: Human
Sample Type: Recombinant Protein
Application: Bioassay
Authors: V Glorian, J Allègre, J Berthelet, B Dumetier, PM Boutanquoi, N Droin, C Kayaci, J Cartier, S Gemble, G Marcion, D Gonzalez, R Boidot, C Garrido, O Michaud, E Solary, L Dubrez
Cell Death Dis, 2017;8(5):e2816.
Species: Human
Sample Type: Recombinant Protein
Application: Bioassay
DNA damage and S phase-dependent E2F1 stabilization requires the cIAP1 E3-ubiquitin ligase and is associated with K63-poly-ubiquitination on lysine 161/164 residues
Authors: V Glorian, J Allègre, J Berthelet, B Dumetier, PM Boutanquoi, N Droin, C Kayaci, J Cartier, S Gemble, G Marcion, D Gonzalez, R Boidot, C Garrido, O Michaud, E Solary, L Dubrez
Cell Death Dis, 2017;8(5):e2816.
Species: Bacteria - E. Coli
Sample Type: Protein
Application: Bioassay
Authors: V Glorian, J Allègre, J Berthelet, B Dumetier, PM Boutanquoi, N Droin, C Kayaci, J Cartier, S Gemble, G Marcion, D Gonzalez, R Boidot, C Garrido, O Michaud, E Solary, L Dubrez
Cell Death Dis, 2017;8(5):e2816.
Species: Bacteria - E. Coli
Sample Type: Protein
Application: Bioassay
In vitro analysis of RQC activities provides insights into the mechanism and function of CAT tailing
Authors: BA Osuna, CJ Howard, S Kc, A Frost, DE Weinberg
Elife, 2017;6(0):.
Species: Saccharomyces cerevisiae
Sample Type: RNA
Application: Bioassay
Authors: BA Osuna, CJ Howard, S Kc, A Frost, DE Weinberg
Elife, 2017;6(0):.
Species: Saccharomyces cerevisiae
Sample Type: RNA
Application: Bioassay
Negative regulation of the RLH signaling by the E3 ubiquitin ligase RNF114
Authors: B Lin, Q Ke, H Li, NS Pheifer, DC Velliquett, DW Leaman
Cytokine, 2017;0(0):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Authors: B Lin, Q Ke, H Li, NS Pheifer, DC Velliquett, DW Leaman
Cytokine, 2017;0(0):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
In vitro characterization of six STUB1 variants in spinocerebellar ataxia 16 reveals altered structural properties for the encoded CHIP proteins
Authors: Y Pakdaman, M Sanchez-Gu, R Kleppe, S Erdal, HJ Bustad, L Bjørkhaug, K Haugarvoll, C Tzoulis, K Heimdal, PM Knappskog, S Johansson, I Aukrust
Biosci. Rep., 2017;37(2):.
Species: Human
Sample Type: Protein
Application: Bioassay
Authors: Y Pakdaman, M Sanchez-Gu, R Kleppe, S Erdal, HJ Bustad, L Bjørkhaug, K Haugarvoll, C Tzoulis, K Heimdal, PM Knappskog, S Johansson, I Aukrust
Biosci. Rep., 2017;37(2):.
Species: Human
Sample Type: Protein
Application: Bioassay
H3 ubiquitination by NEDD4 regulates H3 acetylation and tumorigenesis
Authors: X Zhang, B Li, AH Rezaeian, X Xu, PC Chou, G Jin, F Han, BS Pan, CY Wang, J Long, A Zhang, CY Huang, FJ Tsai, CH Tsai, C Logothetis, HK Lin
Nat Commun, 2017;8(0):14799.
Species: N/A
Sample Type: Recombinant Protein
Application: Bioassay
Authors: X Zhang, B Li, AH Rezaeian, X Xu, PC Chou, G Jin, F Han, BS Pan, CY Wang, J Long, A Zhang, CY Huang, FJ Tsai, CH Tsai, C Logothetis, HK Lin
Nat Commun, 2017;8(0):14799.
Species: N/A
Sample Type: Recombinant Protein
Application: Bioassay
The E3 ubiquitin ligase RNF185 facilitates the cGAS-mediated innate immune response
Authors: Q Wang, L Huang, Z Hong, Z Lv, Z Mao, Y Tang, X Kong, S Li, Y Cui, H Liu, L Zhang, X Zhang, L Jiang, C Wang, Q Zhou
PLoS Pathog, 2017;13(3):e1006264.
Species: N/A
Sample Type: Protein
Application: Bioassay
Authors: Q Wang, L Huang, Z Hong, Z Lv, Z Mao, Y Tang, X Kong, S Li, Y Cui, H Liu, L Zhang, X Zhang, L Jiang, C Wang, Q Zhou
PLoS Pathog, 2017;13(3):e1006264.
Species: N/A
Sample Type: Protein
Application: Bioassay
The Nedd8 Non-covalent Binding Region in the Smurf HECT Domain is Critical to its Ubiquitn Ligase Function
Authors: S He, Y Cao, P Xie, G Dong, L Zhang
Sci Rep, 2017;7(0):41364.
Species: Human
Sample Type: Cell Lysates
Application: Bioassay
Authors: S He, Y Cao, P Xie, G Dong, L Zhang
Sci Rep, 2017;7(0):41364.
Species: Human
Sample Type: Cell Lysates
Application: Bioassay
Ubiquitination and regulation of AURKA identifies a hypoxia-independent E3 ligase activity of VHL
Authors: E Hasanov, G Chen, P Chowdhury, J Weldon, Z Ding, E Jonasch, S Sen, CL Walker, R Dere
Oncogene, 2017;0(0):.
Species: N/A
Sample Type: Protein
Application: Ubiquitination
Authors: E Hasanov, G Chen, P Chowdhury, J Weldon, Z Ding, E Jonasch, S Sen, CL Walker, R Dere
Oncogene, 2017;0(0):.
Species: N/A
Sample Type: Protein
Application: Ubiquitination
Structural insights into Parkin substrate lysine targeting from minimal Miro substrates
Sci Rep, 2016;6(0):33019.
Species: Human
Sample Type: Protein
Application: Bioassay
Sci Rep, 2016;6(0):33019.
Species: Human
Sample Type: Protein
Application: Bioassay
Neddylation E2 UBE2F promotes the survival of lung cancer cells by activating CRL5 to degrade NOXA via the K11 linkage
Clin Cancer Res, 2016;0(0):.
Species: Human
Sample Type: Protein
Application: Ubiquitination
Clin Cancer Res, 2016;0(0):.
Species: Human
Sample Type: Protein
Application: Ubiquitination
Regulation of the MDM2-p53 pathway by the nucleolar protein CSIG in response to nucleolar stress
Sci Rep, 2016;6(0):36171.
Species: Human
Sample Type: Protein
Application: Bioassay
Sci Rep, 2016;6(0):36171.
Species: Human
Sample Type: Protein
Application: Bioassay
Higher-order oligomerization promotes localization of SPOP to liquid nuclear speckles
EMBO J, 2016;0(0):.
Species: Human
Sample Type: Recombinant Protein
Application: Bioassay
EMBO J, 2016;0(0):.
Species: Human
Sample Type: Recombinant Protein
Application: Bioassay
Role of SUMO activating enzyme in cancer stem cell maintenance and self-renewal
Nat Commun, 2016;7(0):12326.
Species: N/A
Sample Type: Recombinant Protein
Application: Bioassay
Nat Commun, 2016;7(0):12326.
Species: N/A
Sample Type: Recombinant Protein
Application: Bioassay
A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase
Authors: Mary E Matyskiela
Nature, 2016;0(0):.
Species: N/A
Sample Type: Protein
Application: Bioassay
Authors: Mary E Matyskiela
Nature, 2016;0(0):.
Species: N/A
Sample Type: Protein
Application: Bioassay
Ubiquitin-conjugating enzyme Cdc34 and ubiquitin ligase Skp1-cullin-F-box ligase (SCF) interact through multiple conformations.
Authors: Sandoval D, Hill S, Ziemba A, Lewis S, Kuhlman B, Kleiger G
J Biol Chem, 2015;290(2):1106-18.
Species: Bacteria - E. Coli
Sample Type: Whole Cells
Authors: Sandoval D, Hill S, Ziemba A, Lewis S, Kuhlman B, Kleiger G
J Biol Chem, 2015;290(2):1106-18.
Species: Bacteria - E. Coli
Sample Type: Whole Cells
An anti-ubiquitin antibody response in transitional cell carcinoma of the urinary bladder.
Authors: Ardelt P, Ebbing J, Adams F, Reiss C, Arap W, Pasqualini R, Bachmann A, Wetterauer U, Riedmiller H, Kneitz B
PLoS ONE, 2015;10(3):e0118646.
Species: Human
Sample Type: Serum
Application: ELISA
Authors: Ardelt P, Ebbing J, Adams F, Reiss C, Arap W, Pasqualini R, Bachmann A, Wetterauer U, Riedmiller H, Kneitz B
PLoS ONE, 2015;10(3):e0118646.
Species: Human
Sample Type: Serum
Application: ELISA
Cellular inhibitor of apoptosis (cIAP)-mediated ubiquitination of phosphofurin acidic cluster sorting protein 2 (PACS-2) negatively regulates tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) cytotoxicity.
Authors: Guicciardi, Maria Eu, Werneburg, Nathan W, Bronk, Steven F, Franke, Adrian, Yagita, Hideo, Thomas, Gary, Gores, Gregory
PLoS ONE, 2014;9(3):e92124.
Species: N/A
Sample Type: Recombinant Protein
Application: Bioassay
Authors: Guicciardi, Maria Eu, Werneburg, Nathan W, Bronk, Steven F, Franke, Adrian, Yagita, Hideo, Thomas, Gary, Gores, Gregory
PLoS ONE, 2014;9(3):e92124.
Species: N/A
Sample Type: Recombinant Protein
Application: Bioassay
The ubiquitin ligase ASB4 promotes trophoblast differentiation through the degradation of ID2.
Authors: Townley-Tilson, W H Davi, Wu, Yaxu, Ferguson, James E, Patterson, Cam
PLoS ONE, 2014;9(2):e89451.
Species: Human
Sample Type: Whole Cells
Application: Ubiquitination
Authors: Townley-Tilson, W H Davi, Wu, Yaxu, Ferguson, James E, Patterson, Cam
PLoS ONE, 2014;9(2):e89451.
Species: Human
Sample Type: Whole Cells
Application: Ubiquitination
Dimeric Ube2g2 simultaneously engages donor and acceptor ubiquitins to form Lys48-linked ubiquitin chains.
Authors: Liu, Weixiao, Shang, Yonglian, Zeng, Yan, Liu, Chao, Li, Yanchang, Zhai, Linhui, Wang, Pan, Lou, Jizhong, Xu, Ping, Ye, Yihong, Li, Wei
EMBO J, 2014;33(1):46-61.
Species: N/A
Sample Type: Recombinant Protein
Application: Bioassay
Authors: Liu, Weixiao, Shang, Yonglian, Zeng, Yan, Liu, Chao, Li, Yanchang, Zhai, Linhui, Wang, Pan, Lou, Jizhong, Xu, Ping, Ye, Yihong, Li, Wei
EMBO J, 2014;33(1):46-61.
Species: N/A
Sample Type: Recombinant Protein
Application: Bioassay
Pin1 modulates ERalpha levels in breast cancer through inhibition of phosphorylation-dependent ubiquitination and degradation.
Authors: Rajbhandari P, Schalper K, Solodin N, Ellison-Zelski S, Ping Lu K, Rimm D, Alarid E
Oncogene, 2014;33(11):1438-47.
Species: N/A
Sample Type: Recombinant Protein
Application: Bioassay
Authors: Rajbhandari P, Schalper K, Solodin N, Ellison-Zelski S, Ping Lu K, Rimm D, Alarid E
Oncogene, 2014;33(11):1438-47.
Species: N/A
Sample Type: Recombinant Protein
Application: Bioassay
The spindle and kinetochore-associated (Ska) complex enhances binding of the anaphase-promoting complex/cyclosome (APC/C) to chromosomes and promotes mitotic exit.
Authors: Sivakumar, Sushama, Daum, John R, Tipton, Aaron R, Rankin, Susannah, Gorbsky, Gary J
Mol Biol Cell, 2014;25(5):594-605.
Species: Human
Sample Type: Cell Lysates
Application: Bioassay
Authors: Sivakumar, Sushama, Daum, John R, Tipton, Aaron R, Rankin, Susannah, Gorbsky, Gary J
Mol Biol Cell, 2014;25(5):594-605.
Species: Human
Sample Type: Cell Lysates
Application: Bioassay
Stochastic gate dynamics regulate the catalytic activity of ubiquitination enzymes.
Authors: Rout, Manoj K, Hodge, Curtis D, Markin, Craig J, Xu, Xin, Glover, J N Mark, Xiao, Wei, Spyracopoulos, Leo
J Am Chem Soc, 2014;136(50):17446-58.
Species: N/A
Sample Type: Protein
Application: Bioassay
Authors: Rout, Manoj K, Hodge, Curtis D, Markin, Craig J, Xu, Xin, Glover, J N Mark, Xiao, Wei, Spyracopoulos, Leo
J Am Chem Soc, 2014;136(50):17446-58.
Species: N/A
Sample Type: Protein
Application: Bioassay
CXC chemokine receptor 4 signaling upon co-activation with stromal cell-derived factor-1alpha and ubiquitin.
Authors: Tripathi A, Davis J, Staren D, Volkman B, Majetschak M
Cytokine, 2013;65(2):121-5.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Authors: Tripathi A, Davis J, Staren D, Volkman B, Majetschak M
Cytokine, 2013;65(2):121-5.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
A pathogen type III effector with a novel E3 ubiquitin ligase architecture.
Authors: Singer, Alexande, Schulze, Sebastia, Skarina, Tatiana, Xu, Xiaohui, Cui, Hong, Eschen-Lippold, Lennart, Egler, Monique, Srikumar, Tharan, Raught, Brian, Lee, Justin, Scheel, Dierk, Savchenko, Alexei, Bonas, Ulla
PLoS Pathog, 2013;9(1):e1003121.
Species: N/A
Sample Type: Recombinant Protein
Application: Bioassay
Authors: Singer, Alexande, Schulze, Sebastia, Skarina, Tatiana, Xu, Xiaohui, Cui, Hong, Eschen-Lippold, Lennart, Egler, Monique, Srikumar, Tharan, Raught, Brian, Lee, Justin, Scheel, Dierk, Savchenko, Alexei, Bonas, Ulla
PLoS Pathog, 2013;9(1):e1003121.
Species: N/A
Sample Type: Recombinant Protein
Application: Bioassay
Parkin ubiquitinates Tar-DNA binding protein-43 (TDP-43) and promotes its cytosolic accumulation via interaction with histone deacetylase 6 (HDAC6).
Authors: Hebron, Michaeli, Lonskaya, Irina, Sharpe, Kaydee, Weerasinghe, Puwakdan, Algarzae, Norah K, Shekoyan, Ashot R, Moussa, Charbel
J Biol Chem, 2013;288(6):4103-15.
Species: N/A
Sample Type: Recombinant Protein
Application: Bioassay
Authors: Hebron, Michaeli, Lonskaya, Irina, Sharpe, Kaydee, Weerasinghe, Puwakdan, Algarzae, Norah K, Shekoyan, Ashot R, Moussa, Charbel
J Biol Chem, 2013;288(6):4103-15.
Species: N/A
Sample Type: Recombinant Protein
Application: Bioassay
Ubiquitination increases parkin activity to promote autophagic alpha-synuclein clearance.
Authors: Lonskaya I, Desforges N, Hebron M, Moussa C
PLoS ONE, 2013;8(12):e83914.
Species: N/A
Sample Type: Recombinant Protein
Application: Enzyme Assay
Authors: Lonskaya I, Desforges N, Hebron M, Moussa C
PLoS ONE, 2013;8(12):e83914.
Species: N/A
Sample Type: Recombinant Protein
Application: Enzyme Assay
DNA damage-induced heterogeneous nuclear ribonucleoprotein K sumoylation regulates p53 transcriptional activation.
Authors: Pelisch F, Pozzi B, Risso G, Munoz M, Srebrow A
J Biol Chem, 2012;287(36):30789-99.
Species: N/A
Sample Type: Protein
Application: Bioassay
Authors: Pelisch F, Pozzi B, Risso G, Munoz M, Srebrow A
J Biol Chem, 2012;287(36):30789-99.
Species: N/A
Sample Type: Protein
Application: Bioassay
Characterization of ML-IAP protein stability and physiological role in vivo.
Authors: Varfolomeev, Eugene, Moradi, Elham, Dynek, Jasmin N, Zha, Jiping, Fedorova, Anna V, Deshayes, Kurt, Fairbrother, Wayne J, Newton, Kim, Le Couter, Jennifer, Vucic, Domagoj
Biochem J, 2012;447(3):427-36.
Species: Human
Sample Type: Protein
Application: Bioassay
Authors: Varfolomeev, Eugene, Moradi, Elham, Dynek, Jasmin N, Zha, Jiping, Fedorova, Anna V, Deshayes, Kurt, Fairbrother, Wayne J, Newton, Kim, Le Couter, Jennifer, Vucic, Domagoj
Biochem J, 2012;447(3):427-36.
Species: Human
Sample Type: Protein
Application: Bioassay
p47 negatively regulates IKK activation by inducing the lysosomal degradation of polyubiquitinated NEMO.
Authors: Shibata Y, Oyama M, Kozuka-Hata H, Han X, Tanaka Y, Gohda J, Inoue J
Nat Commun, 2012;3(0):1061.
Species: N/A
Sample Type: Recombinant Protein
Application: Binding Assay
Authors: Shibata Y, Oyama M, Kozuka-Hata H, Han X, Tanaka Y, Gohda J, Inoue J
Nat Commun, 2012;3(0):1061.
Species: N/A
Sample Type: Recombinant Protein
Application: Binding Assay
The F-box protein FBXO44 mediates BRCA1 ubiquitination and degradation.
Authors: Lu, Yunzhe, Li, Jiezhi, Cheng, Dongmei, Parameswaran, Balaji, Zhang, Shaohua, Jiang, Zefei, Yew, P Renee, Peng, Junmin, Ye, Qinong, Hu, Yanfen
J Biol Chem, 2012;287(49):41014-22.
Species: N/A
Sample Type: Recombinant Protein
Application: in vitro ubiquitination
Authors: Lu, Yunzhe, Li, Jiezhi, Cheng, Dongmei, Parameswaran, Balaji, Zhang, Shaohua, Jiang, Zefei, Yew, P Renee, Peng, Junmin, Ye, Qinong, Hu, Yanfen
J Biol Chem, 2012;287(49):41014-22.
Species: N/A
Sample Type: Recombinant Protein
Application: in vitro ubiquitination
ERalpha phosphorylation at Y537 by Src triggers E6-AP-ERalpha binding, ERalpha ubiquitylation, promoter occupancy, and target gene expression.
Authors: Sun J, Zhou W, Kaliappan K, Nawaz Z, Slingerland J
Mol Endocrinol, 2012;26(9):1567-77.
Species: Human
Sample Type: Protein
Application: Bioassay
Authors: Sun J, Zhou W, Kaliappan K, Nawaz Z, Slingerland J
Mol Endocrinol, 2012;26(9):1567-77.
Species: Human
Sample Type: Protein
Application: Bioassay
The APC/C subunit Mnd2/Apc15 promotes Cdc20 autoubiquitination and spindle assembly checkpoint inactivation.
Authors: Foster S, Morgan D
Mol Cell, 2012;47(6):921-32.
Species: N/A
Sample Type: Protein
Application: Bioassay
Authors: Foster S, Morgan D
Mol Cell, 2012;47(6):921-32.
Species: N/A
Sample Type: Protein
Application: Bioassay
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