抗Human Cystatin C Biotinylated抗体(Anti-Human Cystatin C Biotinylated antibody)
掲載日情報：2021/01/28 現在Webページ番号：195198
Human Cystatin C Biotinylatedに対する抗体(Anti-Human Cystatin C Biotinylated )です。
※ 本製品は研究用です。研究用以外には使用できません。
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- 価格
- Product Details
- Applications and Data
- References
- Related Research Areas
- Summary
- Related Product & Information
- Citations
価格
[在庫・価格 ：2024年06月07日 09時35分現在]
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Anti-Human Cystatin C Biotinylated MAb |
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[在庫・価格 ：2024年06月07日 09時35分現在]
Anti-Human Cystatin C Biotinylated MAb
文献数： 1
- 商品コード：BAM11961
- メーカー：RSD
- 包装：100μg
- 価格：¥117,000
- 在庫：無(未発注)
- 納期：10日程度 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等：
| 説明文 |
マッチドペア：Human Cystatin C サンドイッチELISAの検出用抗体として利用可能，補足用抗体として#MAB11962-500，スタンダードとして#1196-PI-010を用いる。 別名：ARMD11 クローン：197821 Genbank No： 1471 Protein Accession No： P01034 |
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| 保存条件 | 法規備考 | ||
| 抗原種 | Human | 免疫動物 | Mouse |
| 交差性 | Human | 適用 | ELISA |
| 標識 | Biotin | 性状 | Protein A/G Affinity Purified |
| 吸収処理 | クラス | IgG | |
| クロナリティ | Monoclonal | フォーマット | |
| 掲載カタログ |
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| 製品記事 |
Proteome Profiler™ Human Hematopoietic and Non-hematopoietic Soluble Receptor Antibody Arrays |
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| 関連記事 |
R&D Systems(R&Dシステムズ)社 ELISA用ペア抗体を使用したELISA 構築ガイド |
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Product Details
| Species Reactivity | Human |
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| Label | Biotin |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Cystatin CSer27-Ala146Accession # P01034 |
| Source | Monoclonal Mouse IgG2B Clone # 197821 |
| Purification | Protein A or G purified from hybridoma culture supernatant |
| Specificity | Detects human Cystatin C in ELISAs. In sandwich immunoassays, no cross-reactivity or interference with recombinant human Cystatin A, B, D, E/M, F, S, SA, SN, X/Z/P, or recombinant mouse Cystatin C is observed. |
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Applications and Data
| Recommended Concentration | Sample | |
| Human Cystatin C Sandwich Immunoassay | Reagent | |
| ELISA Capture (Matched Antibody Pair) | 2-8 µg/mL | Human Cystatin C Antibody (Catalog #MAB11962R ) |
| ELISA Detection (Matched Antibody Pair) | 0.5-2.0 µg/mL | Human Cystatin C Biotinylated Antibody (Catalog #BAM11961 ) |
| ELISA Standard | Recombinant Human Cystatin C Protein, CF (Catalog #1196-PI ) | |
| Please Note: Optimal dilutions should be determined by each laboratory for each application.General Protocolsare available in the Technical Information section on our website. | Preparation and Storage | |
| Reconstitution | Reconstitute at 0.5 mg/mL in sterile PBS. | Reconstitution Buffer Available |
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. | |
| Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. | |
| 1 month, 2 to 8 °C under sterile conditions after reconstitution. | ||
| 6 months, -20 to -70 °C under sterile conditions after reconstitution. | ||
| Background: Cystatin C | Cystatin C is a member of family 2 of the Cystatin superfamily (1). It is involved in processes such as tumor invasion and metastasis, inflammation and some neurological diseases. It inhibits many cysteine proteases such as papain and cathepsins B, H, K, L and S (2, 3). It is ubiquitous in human tissues and body fluids. A point mutation in the gene coding for the 120 amino acid mature Cystatin C causes a hereditary form of amyloid angiopathy in which the protein variant (Leu68 to Gln) is deposited in the cerebral arteries, leading to fatal cerebral hemorrhage (4). Cystatin C may have additional clinical applications. For example, it is a good marker for glomerular filtration rate (5). |
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References
| Reed, C.H. (2000) British J. Biomed. Sci. 57:323. | |
| Janowski, R. et al. (2001) Nat. Struct. Biol. 8:316. | |
| Abrahamson, M. (1994) Methods Enzymol. 244:685. | |
| Abrahamson, M. et al. (1992) Hum. Genet. 89:377. | |
| Laterza, O.F. et al. (2002) Clin. Chem. 48:699. | |
| Entrez Gene IDs: | 1471 (Human); 13010 (Mouse); 25307 (Rat) |
| Alternate Names: | ARMD11; bA218C14.4 (cystatin C); CST3; cystatin 3; cystatin C (amyloid angiopathy and cerebral hemorrhage); Cystatin C; cystatin-3; cystatin-C; Gamma-trace; MGC117328; Neuroendocrine basic polypeptide; Post-gamma-globulin |
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Related Research Areas
| Cysteine Proteases and Regulators | ||||||||
| Renal Markers | ||||||||
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| Images | Ratings | Applications | Species | Reviewed By | Date | Details | ||
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| Excellent | ELISA | Human | Anonymous | 12/18/2017 | ||||
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Summary
| Application | ELISA |
| Sample Tested | EDTA Plasma |
| Species | Human |
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Related Product & Information
| Background | Cystatin C |
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| background_content | Background: Cystatin C Cystatin C is a member of family 2 of the Cystatin superfamily (1). It is involved in processes such as tumor invasion and metastasis, inflammation and some neurological diseases. It inhibits many cysteine proteases such as papain and cathepsins B, H, K, L and S (2, 3). It is ubiquitous in human tissues and body fluids. A point mutation in the gene coding for the 120 amino acid mature Cystatin C causes a hereditary form of amyloid angiopathy in which the protein variant (Leu68 to Gln) is deposited in the cerebral arteries, leading to fatal cerebral hemorrhage (4). Cystatin C may have additional clinical applications. For example, it is a good marker for glomerular filtration rate (5). |
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Citations
- Extracellular Vesicle Proteins Associated with Systemic Vascular Events Correlate with Heart Failure: An Observational Study in a Dyspnoea Cohort.
Authors: Zhang Y, Vernooij F, Ibrahim I, Ooi S, Gijsberts C, Schoneveld A, Sen K, den Ruijter H, Timmers L, Richards A, Jong C, Mazlan I, Wang J, Lam C, de Kleijn D
PLoS ONE, 2016;11(1):e0148073.
Species: Human
Sample Type: Plasma
Application: ELISA Development
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