抗Histone H3 [RM188]抗体 | Anti-Histone H3 [RM188] antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	Western Blot of recombinant Histone H3.3 andHistone H3.1 proteins, A375, HEK293, HeLa and SK-MEL-2 whole cell lysates, using RM188at 0.025 ug/mL, showed a band of recombinant H3.1 and H3.3 proteins, and total histone H3 in A375, HEK293, HeLa and SK-MEL-2 cells.
	RM188 reacts to both Histone H3.1 and Histone H3.3.

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製品情報

Host	Rabbit
Clonality	Monoclonal
Clone Name	RM188
Isotype	IgG
Application	WB, ELISA, Multiplexing
Reactivity	Human

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	Assay dependent
ELISA	Assay dependent
Multiplexing	Assay dependent
Note : sELISA Capture : GTX60888, Detection : GTX60886/GTX60885 ; Capture : GTX60883, Detection : GTX60888

Not tested in other applications.

Specificity/Sensitivity	This antibody reacts to all Histone H3 proteins, independent of post-translational modifications. No cross reactivity with other histone proteins.

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PROPERTIES

Form	Liquid
Buffer	PBS with 50% Glycerol and 1% BSA. 0.09% Sodium azide was added as a preservative.
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	A peptide corresponding to the C-terminus of human Histone H3.
Purification	Protein A affinity purified from an animal origin–free culture supernatant
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms

H3.3A Antibody , H3 histone, family 3A Antibody , H3F3A Antibody , H3F3 Antibody , Histone H3 antibody

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded is a replication-independent member of the histone H3 family. [provided by RefSeq, Jul 2008]

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