抗HP, Mouse-Mono(UMAB10) UltraMAB抗体 | Anti-HP, Mouse-Mono(UMAB10) UltraMAB Antibody
掲載日情報：2015/11/06 現在Webページ番号：177883
OriGene社の抗HP, Mouse-Mono(UMAB10) UltraMAB抗体です。
本製品は、UltraMAB抗体シリーズ(三次元構造を有する組換え体ヒトタンパク質の全長を抗原として作製したモノクローナル抗体)です。
※本製品は研究用です。研究用以外には使用できません。
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価格
[在庫・価格 ：2024年05月18日 11時15分現在]
※ 表示されている納期は弊社に在庫が無く、取り寄せた場合の納期目安となります。
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[在庫・価格 ：2024年05月18日 11時15分現在]
※ 表示されている納期は弊社に在庫が無く、取り寄せた場合の納期目安となります。
Anti-HP, Mouse-Mono(UMAB10), UltraMAB
文献数： 0
- 商品コード：UM570010
- メーカー：ORI
- 包装：30μl
- 価格：¥74,000
- 在庫：無(未発注)
- 納期：3～4週間 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等：
| 説明文 |
クローン：UMAB10 Genbank No： 3240 Gene Accession No： NM_005143 |
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| 法規制等 | |||
| 保存条件 | 法規備考 | ||
| 抗原種 | 免疫動物 | Mouse | |
| 交差性 | Human | 適用 | IF,IHC,IP,Western Blot |
| 標識 | Unlabeled | 性状 | Affinity Purified |
| 吸収処理 | クラス | IgG | |
| クロナリティ | Monoclonal | フォーマット | |
| 掲載カタログ |
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| 製品記事 |
UltraMAB抗体 |
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| 関連記事 | |||
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UltraMAB抗体について
OriGene社製品の中でも、特にUltraMAB抗体シリーズは、ヒト組織の免疫染色(IHC)に適した非常に特異性の高いモノクローナル抗体です。抗原にはTrueMAB抗体と同様、組換え体ヒト全長タンパク質を使用しています。1万種類を超えるタンパク質をスポットしたマイクロアレイを用い、標的タンパク質以外の分子との交差反応がないことを確認済みの、癌研究・病理学・解剖学向けの製品です。
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Product Data
| Immunogen | Full length human recombinant protein of human HP (NP_005134) produced in HEK293T cell. | ||
|---|---|---|---|
| Clone Name | Clone UMAB10 | Isotype | IgG1 |
| Species Reactivity | Human | Concentration | 0.5~1.0 mg/ml (Lot Dependent) |
| Guaranteed Application | WB, IHC, IF, 10K-CHIP | Suggested Dilutions | WB 1:500~2000, IF 1:100 |
| Buffer | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. | ||
| Purification | Purified from mouse ascites fluids by affinity chromatography | ||
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Reference Data
| Target Name | Homo sapiens haptoglobin (HP), transcript variant 1 | ||
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| Alternative Name | BP; HP2ALPHA2; HPA1S | ||
| Database Link | NP_005134 | ||
| Function | This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. | ||
| Related Pathway | |||
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Image
| Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-HP monoclonal antibody (Clone UMAB10) at 1:500. | |
| Western Blot analysis of 10 different human tissue lysates (10ug) by using anti-HP monoclonal antibody (clone UMAB10, 1:500) | |
| Immunohistochemical staining of paraffin-embedded breast tissue using anti-HP mouse monoclonal antibody. (Clone UMAB10, dilution 1:100; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) | |
| Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-HP mouse monoclonal antibody. (Clone UMAB10, dilution 1:100; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) | |
| Immunohistochemical staining of paraffin-embedded colon tissue using anti-HPmouse monoclonal antibody. (Clone UMAB10, dilution 1:100; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) | |
| Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-HPmouse monoclonal antibody. (Clone UMAB10, dilution 1:100; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) | |
| Immunohistochemical staining of paraffin-embedded lung tissue using anti-HPmouse monoclonal antibody. (Clone UMAB10, dilution 1:100; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) | |
| Immunohistochemical staining of paraffin-embedded Carcinoma of lung tissue using anti-HPmouse monoclonal antibody. (Clone UMAB10, dilution 1:100; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) | |
| Immunohistochemical staining of paraffin-embedded Adenocarcinoma of ovary tissue using anti-HPmouse monoclonal antibody. (Clone UMAB10, dilution 1:100; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) | |
| Immunohistochemical staining of paraffin-embedded pancreas tissue using anti-HPmouse monoclonal antibody. (Clone UMAB10, dilution 1:100; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) | |
| Immunohistochemical staining of paraffin-embedded Carcinoma of pancreas tissue using anti-HPmouse monoclonal antibody. (Clone UMAB10, dilution 1:100; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) | |
| Immunohistochemical staining of paraffin-embedded prostate tissue using anti-HPmouse monoclonal antibody. (Clone UMAB10, dilution 1:100; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) | |
| Immunohistochemical staining of paraffin-embedded Carcinoma of prostate tissue using anti-HPmouse monoclonal antibody. (Clone UMAB10, dilution 1:100; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) | |
| Immunohistochemical staining of paraffin-embedded human liver cancer using anti-HP clone UMAB10 mouse monoclonal antibody at 1:200 dilution of 1.0 mg/mL using Polink2 Broad HRP DAB for detection. UM500010 requires HIER with with citrate pH6.0 at 110C for 3 min using pressure chamber/cooker. The tumor cells shows membrane and cytoplasmic staining. | |
| Immunohistochemical staining of paraffin-embedded human ovarian cancer using anti-HP clone UMAB10 mouse monoclonal antibody at 1:200 dilution of 1.0 mg/mL using Polink2 Broad HRP DAB for detection. UM500010 requires HIER with with citrate pH6.0 at 110C for 3 min using pressure chamber/cooker. The tumor cells shows membrane and cytoplasmic staining. | |
| Immunohistochemical staining of paraffin-embedded human gastric cancer seen mainly normal adjacent using anti-HP clone UMAB10 mouse monoclonal antibody at 1:200 with Polink2 Broad HRP DAB detection kit (UM500010); heat-induced epitope retrieval with citrate buffer, pH6.0at 95-100C. Strong cytoplasmic and membraneous staining is seen in gastric glands. | |
| Immunohistochemical staining of paraffin-embedded human placenta using anti-HP clone UMAB10 mouse monoclonal antibody at 1:200 with Polink2 Broad HRP DAB detection kit (UM500010); heat-induced epitope retrieval with citrate buffer, pH6.0at 95-100C. Strong membraneous staining is seen in placenta and adjacent blood. | |
| Immunofluorescent staining of HepG2 cells using anti-HP mouse monoclonal antibody (UM500010, green). Actin filaments were labeled with TRITC-phalloidin (red), and nuclear with DAPI (blue). The three-color overlay image is located at the bottom-right corner. | |
| OriGene overexpression protein microarray chip was immunostained with UltraMAB anti-HP mouse monoclonal antibody (Clone UMAB10). The positive reactive proteins are highlighted with two red arrows in the enlarged subarray. All the positive controls spotted in this subarray are also labeled for clarification. These data show that UltraMAB anti-HP (Clone UMAB10) very specifically recognizes HP antigen on OriGene protein microarray chip. |
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