抗West Nile Virus Envelope抗体 | Anti-West Nile Virus Envelope antibody

• 特長
• 価格
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	ELISA
Reactivity	West Nile virus

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
ELISA	1 μg/mL
Note : ELISA It will detect 10 ng of free peptide at 1 μg/mL.

Not tested in other applications.

Calculated MW	380 kDa. ( Note )
Specificity/Sensitivity	This antibody is specific for West Nile Virus Envelope Internal

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PROPERTIES

Form	Liquid
Buffer	PBS with 0.02% sodium azide.
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	West Nile virus
Immunogen	West Nile virus Envelope antibody was raised against a synthetic peptide corresponding to 15 amino acids near the center of the West Nile virus envelope protein.The immunogen is located within amino acids 500 - 550 of West Nile Virus Envelope.
Purification	Purified by antigen-affinity chromatography
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	West Nile virus Envelope protein , WNV Envelope protein
Background	West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state (reviewed in 1). Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins (1). While the viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway (2), the highly glycosylated envelope protein plays a major role for WNV entry into target cells as this entry can be inhibited by using a recombinant domain III from the envelope glycoprotein (3). The WNV receptor has recently been identified as alpha v beta 3 integrin (4).
Database	・ Gene ID: 912267 ・ UniProt: P06935

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