抗mGluR7抗体 | Anti-mGluR7 antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	IHC-P analysis of human liver tissue using GTX71713 mGluR7 antibody.Antigen retrival : Heat-induced antigen retrievalDilution : 7 μg/ml
	IHC-P analysis of human adrenal tissue using GTX71713 mGluR7 antibody.Antigen retrival : Heat-induced antigen retrievalDilution : 7 μg/ml

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P
Reactivity	Human

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	Assay dependent
IHC-P	7 μg/ml

Not tested in other applications.

Calculated MW	102 kDa. ( Note )
Predict Reactivity	Mouse, Rat, Rabbit, Bovine, Dog, Chicken, Monkey, Chimpanzee, Gibbon, Gorilla, Horse, Marmoset, Opossum, Orangutan, Panda, Turkey(>80% identity)

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PROPERTIES

Form	Liquid
Buffer	PBS, 0.1% sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Synthetic 20 amino acid peptide from N- terminal extracellular domain of human mGluR7.
Purification	Purified by affinity chromatography
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	glutamate metabotropic receptor 7 , GLUR7 , GPRC1G , MGLU7 , MGLUR7 , PPP1R87
Cellular Localization	Cell membrane; Multi-pass membrane protein
Background	L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
Database	・ Gene ID: 2917 GRM7 ・ UniProt: Q14831 GRM7

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