抗CEA [1106]抗体 | Anti-CEA [1106] antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	FACS analysis of BxPC-3 cells using GTX15677 CEA antibody [1106]. Pink histogram : Primary antibody Black histogram : Isotype control antibodyDilution : 10 μg/ml in PBS + 5% FCS
	ICC/IF analysis of BxPC-3 cells using GTX15677 CEA antibody [1106]. Green : Primary antibodyBlue : NucleiFixation : 4% paraformaldehydePermeabilization : 0.1% Trito X-100 for 10 minutesDilution : 10 μg/ml in blocking buffer for 1 hour at room temperature
	WB analysis of 20 ug of BxPC-3, HeLa, and HepG2 whole cell lysates per well using GTX15677 CEA antibody [1106]. Dilution : 1 μg/ml

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製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	1106
Isotype	IgG1
Application	WB, ICC/IF, FACS, IP, ELISA, RIA
Reactivity	Human

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	1μg/ml
ICC/IF	Assay dependent
FACS	5-20μg/ml
IP	Assay dependent
ELISA	Assay dependent
RIA	Assay dependent

Not tested in other applications.

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PROPERTIES

Form	Liquid
Buffer	0.01M potassium phosphate, 0.135M NaCl, 2.5mM KCl, 1mg/ml BSA, 0.05% sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Purified CEA from pooled tumors
Purification	Protein A purified
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Background

This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immun

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