価格表
在庫・価格 : 2025年04月29日 11時02分 現在
商品名 | 商品コード | メーカー | 包装 | 価格 | 在庫 | リスト |
---|---|---|---|---|---|---|
Anti-HEC1, Mouse-Mono(9G3.23) データシート |
GTX70268 |
GNTジーンテックス GeneTex International Corporation |
100 μl | ¥85,000 |
無 (未発注) |
追加 |
在庫・価格 : 2025年04月29日 11時02分 現在
使用文献
- No.: 1
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文献情報:
Zeng, K. et al. (2010) J Cell Biol. 191:1315-32.
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備考:
ICC/IF, Immunoprecipitation, Western blot -
参照:
- No.: 2
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文献情報:
Zheng L et al. Retinoblastoma protein enhances the fidelity of chromosome segregation mediated by hsHec1p. Mol. Cell. Biol. 2000 May;20(10):3529-37
Zheng L et al
2000/01/01
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備考:
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参照:
- No.: 3
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文献情報:
Martin-Lluesma S et al. Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2. Science 2002 Sep;297(5590):2267-70
Martin-Lluesma S et al
2002/01/01
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備考:
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参照:
- No.: 4
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文献情報:
Klein UR et al. Centromere targeting of the chromosomal passenger complex requires a ternary subcomplex of Borealin, Survivin, and the N-terminal domain of INCENP. Mol. Biol. Cell 2006 Jun;17(6):2547-58
Klein UR et al
2006/01/01
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備考:
Application: Western blot, Reactivity: Human -
参照:
- No.: 5
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文献情報:
DeLuca JG et al. Kinetochore microtubule dynamics and attachment stability are regulated by Hec1. Cell 2006 Dec;127(5):969-82
DeLuca JG et al
2006/01/01
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備考:
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参照:
- No.: 6
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文献情報:
Montembault E et al. PRP4 is a spindle assembly checkpoint protein required for MPS1, MAD1, and MAD2 localization to the kinetochores. J. Cell Biol. 2007 Nov;179(4):601-9
Montembault E et al
2007/01/01
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備考:
Application: ICC/IF, Reactivity: Human -
参照:
- No.: 7
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文献情報:
Barr AR et al. MCAK-independent functions of ch-Tog/XMAP215 in microtubule plus-end dynamics. Mol. Cell. Biol. 2008 Dec;28(23):7199-211
Barr AR et al
2008/01/01
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備考:
Application: ICC/IF, Reactivity: Human -
参照:
- No.: 8
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文献情報:
Wu G et al. Small molecule targeting the Hec1/Nek2 mitotic pathway suppresses tumor cell growth in culture and in animal. Cancer Res. 2008 Oct;68(20):8393-9
Wu G et al
2008/01/01
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備考:
Application: ICC/IF, -
参照:
- No.: 9
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文献情報:
Chan YW et al. Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly. J. Cell Biol. 2009 Jun;185(5):859-74
Chan YW et al
2009/01/01
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備考:
Application: ICC/IF, Reactivity: Human -
参照:
- No.: 10
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文献情報:
Wu G et al. Hec1 contributes to mitotic centrosomal microtubule growth for proper spindle assembly through interaction with Hice1. Mol. Biol. Cell 2009 Nov;20(22):4686-95
Wu G et al
2009/01/01
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備考:
Application: ICC/IF, Reactivity: Human -
参照:
- No.: 11
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文献情報:
Santaguida S et al. Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine. J. Cell Biol. 2010 Jul;190(1):73-87
Santaguida S et al
2010/01/01
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備考:
Application: ICC/IF, Reactivity: Human -
参照:
- No.: 12
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文献情報:
Petrovic A et al. The MIS12 complex is a protein interaction hub for outer kinetochore assembly. J. Cell Biol. 2010 Sep;190(5):835-52
Petrovic A et al
2010/01/01
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備考:
Application: Western blot, -
参照:
- No.: 13
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文献情報:
Chen Y et al. HEC, a novel nuclear protein rich in leucine heptad repeats specifically involved in mitosis. Mol. Cell. Biol. 1997 Oct;17(10):6049-56
Chen Y et al
1997/01/01
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備考:
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参照:
- No.: 14
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文献情報:
Zeng K et al. Protein phosphatase 6 regulates mitotic spindle formation by controlling the T-loop phosphorylation state of Aurora A bound to its activator TPX2. J. Cell Biol. 2010 Dec;191(7):1315-32
Zeng K et al
2010/01/01
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備考:
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参照:
- No.: 15
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文献情報:
Wong J et al. HURP controls spindle dynamics to promote proper interkinetochore tension and efficient kinetochore capture. J. Cell Biol. 2006 Jun;173(6):879-91
Wong J et al
2006/01/01
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備考:
Application: ICC/IF, Reactivity: Human -
参照:
- No.: 16
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文献情報:
Miller SA et al. Kinetochore attachments require an interaction between unstructured tails on microtubules and Ndc80(Hec1). Curr. Biol. 2008 Nov;18(22):1785-91
Miller SA et al
2008/01/01
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備考:
Application: ICC/IF, Reactivity: Human -
参照:
- No.: 17
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文献情報:
Jang CY et al. DDA3 recruits microtubule depolymerase Kif2a to spindle poles and controls spindle dynamics and mitotic chromosome movement. J. Cell Biol. 2008 Apr;181(2):255-67
Jang CY et al
2008/01/01
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備考:
Application: ICC/IF, Reactivity: Human -
参照:
- No.: 18
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文献情報:
Zhu H et al. FAM29A promotes microtubule amplification via recruitment of the NEDD1-gamma-tubulin complex to the mitotic spindle. J. Cell Biol. 2008 Dec;183(5):835-48
Zhu H et al
2008/01/01
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備考:
Application: ICC/IF, Reactivity: Human -
参照:
- No.: 19
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文献情報:
Serio G et al. Small GTPase Rab5 participates in chromosome congression and regulates localization of the centromere-associated protein CENP-F to kinetochores. Proc. Natl. Acad. Sci. U.S.A. 2011 Oct;108(42):17337-42
Serio G et al
2011/01/01
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備考:
Application: ICC/IF, Reactivity: Human -
参照:
- No.: 20
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文献情報:
Santaguida S et al. Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction. EMBO J. 2011 Apr;30(8):1508-19
Santaguida S et al
2011/01/01
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備考:
Application: ICC/IF, Reactivity: Human -
参照:
- No.: 21
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文献情報:
Tooley JG et al. The Ndc80 complex uses a tripartite attachment point to couple microtubule depolymerization to chromosome movement. Mol. Biol. Cell 2011 Apr;22(8):1217-26
Tooley JG et al
2011/01/01
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備考:
Application: Western blot, Reactivity: Human -
参照:
- No.: 22
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文献情報:
Barnhart MC et al. HJURP is a CENP-A chromatin assembly factor sufficient to form a functional de novo kinetochore. J. Cell Biol. 2011 Jul;194(2):229-43
Barnhart MC et al
2011/01/01
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備考:
Application: ICC/IF, Reactivity: Human -
参照:
- No.: 23
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文献情報:
Screpanti E et al. Direct binding of Cenp-C to the Mis12 complex joins the inner and outer kinetochore. Curr. Biol. 2011 Mar;21(5):391-8
Screpanti E et al
2011/01/01
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備考:
Application: ICC/IF, Reactivity: Human -
参照:
- No.: 24
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文献情報:
Sundin LJ et al. The NDC80 complex proteins Nuf2 and Hec1 make distinct contributions to kinetochore-microtubule attachment in mitosis. Mol. Biol. Cell 2011 Mar;22(6):759-68
Sundin LJ et al
2011/01/01
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備考:
Application: ICC/IF, Reactivity: Human -
参照:
- No.: 25
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文献情報:
Wong J et al. Aurora A regulates the activity of HURP by controlling the accessibility of its microtubule-binding domain. Mol. Biol. Cell 2008 May;19(5):2083-91
Wong J et al
2008/01/01
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備考:
Application: ICC/IF, Reactivity: Human -
参照:
- No.: 26
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文献情報:
Screpanti E et al. A screen for kinetochore-microtubule interaction inhibitors identifies novel antitubulin compounds. PLoS ONE 2010;5(7):e11603
Screpanti E et al
2010/01/01
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備考:
Application: ICC/IF, -
参照:
- No.: 27
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文献情報:
Zanet J et al. A mitosis block links active cell cycle with human epidermal differentiation and results in endoreplication. PLoS ONE 2010;5(12):e15701
Zanet J et al
2010/01/01
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備考:
Application: Immunohistochemistry, Reactivity: Human -
参照:
- No.: 28
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文献情報:
Lawo S et al. Subdiffraction imaging of centrosomes reveals higher-order organizational features of pericentriolar material. Nat. Cell Biol. 2012 Nov;14(11):1148-58
Lawo S et al
2012/01/01
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備考:
Application: Western blot, -
参照:
- No.: 29
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文献情報:
De Antoni A et al. A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora B. J. Cell Biol. 2012 Oct;199(2):269-84
De Antoni A et al
2012/01/01
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備考:
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参照:
- No.: 30
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文献情報:
Matson DR et al. A conserved role for COMA/CENP-H/I/N kinetochore proteins in the spindle checkpoint. Genes Dev. 2012 Mar;26(6):542-7
Matson DR et al
2012/01/01
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備考:
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参照:
- No.: 31
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文献情報:
Chan YW et al. Aurora B controls kinetochore-microtubule attachments by inhibiting Ska complex-KMN network interaction. J. Cell Biol. 2012 Mar;196(5):563-71
Chan YW et al
2012/01/01
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備考:
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参照:
- No.: 32
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文献情報:
Krenn V et al. Structural analysis reveals features of the spindle checkpoint kinase Bub1-kinetochore subunit Knl1 interaction. J. Cell Biol. 2012 Feb;196(4):451-67
Krenn V et al
2012/01/01
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備考:
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参照:
- No.: 33
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文献情報:
Beck J et al. Ubiquitylation-dependent localization of PLK1 in mitosis. Nat. Cell Biol. 2013 Apr;15(4):430-9
Beck J et al
2013/01/01
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備考:
Application: WB-Ag, -
参照:
- No.: 34
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文献情報:
Buheitel J et al. Prophase pathway-dependent removal of cohesin from human chromosomes requires opening of the Smc3-Scc1 gate. EMBO J. 2013 Feb;32(5):666-76
Buheitel J et al
2013/01/01
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備考:
Application: ICC/IF, Reactivity: Human -
参照:
- No.: 35
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文献情報:
Caldas GV et al. KNL1 facilitates phosphorylation of outer kinetochore proteins by promoting Aurora B kinase activity. J. Cell Biol. 2013 Dec;203(6):957-69
Caldas GV et al
2013/01/01
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備考:
Application: Western blot, Reactivity: Human -
参照:
- No.: 36
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文献情報:
Huang LY et al. Activity of a novel Hec1-targeted anticancer compound against breast cancer cell lines in vitro and in vivo. Mol. Cancer Ther. 2014 Jun;13(6):1419-30
Huang LY et al
2014/01/01
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備考:
Application: ICC/IF, Western blot, Reactivity: Human -
参照:
- No.: 37
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文献情報:
Petsalaki E et al. Chk2 prevents mitotic exit when the majority of kinetochores are unattached. J. Cell Biol. 2014 May;205(3):339-56
Petsalaki E et al
2014/01/01
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備考:
Application: ICC/IF, Reactivity: Human -
参照:
- No.: 38
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文献情報:
Matson DR et al. CENP-I and Aurora B act as a molecular switch that ties RZZ/Mad1 recruitment to kinetochore attachment status. J. Cell Biol. 2014 May;205(4):541-54
Matson DR et al
2014/01/01
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備考:
Application: ICC/IF, Reactivity: Human -
参照:
- No.: 39
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文献情報:
Basilico F et al. The pseudo GTPase CENP-M drives human kinetochore assembly. Elife 2014;3:e02978
Basilico F et al
2014/01/01
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備考:
Application: ICC/IF, Western blot, Reactivity: Human -
参照:
- No.: 40
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文献情報:
Huang LY et al. Inhibition of Hec1 as a novel approach for treatment of primary liver cancer. Cancer Chemother. Pharmacol. 2014 Sep;74(3):511-20
Huang LY et al
2014/01/01
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備考:
Application: Western blot, -
参照:
- No.: 41
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文献情報:
H辰fner J et al. Pre-anaphase chromosome oscillations are regulated by the antagonistic activities of Cdk1 and PP1 on Kif18A. Nat Commun 2014;5:4397
H辰fner J et al
2014/01/01
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備考:
Application: ICC/IF, Reactivity: Human -
参照:
- No.: 42
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文献情報:
Espert A et al. PP2A-B56 opposes Mps1 phosphorylation of Knl1 and thereby promotes spindle assembly checkpoint silencing. J. Cell Biol. 2014 Sep;206(7):833-42
Espert A et al
2014/01/01
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備考:
Reactivity: Human -
参照:
- No.: 43
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文献情報:
Wei R et al. Phosphorylation of the Ndc80 complex protein, HEC1, by Nek2 kinase modulates chromosome alignment and signaling of the spindle assembly checkpoint. Mol. Biol. Cell 2011 Oct;22(19):3584-94
Wei R et al
2011/01/01
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備考:
-
参照:
- No.: 44
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文献情報:
Tauchman EC et al. Stable kinetochore-microtubule attachment is sufficient to silence the spindle assembly checkpoint in human cells. Nat Commun 2015;6:10036
Tauchman EC et al
2015/01/01
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備考:
-
参照:
- No.: 45
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文献情報:
DeLuca KF et al. Measuring Kinetochore-Microtubule Attachment Stability in Cultured Cells. Methods Mol. Biol. 2016;1413:147-68
DeLuca KF et al
2016/01/01
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備考:
-
参照:
- No.: 46
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文献情報:
Chung HJ et al. Phosphorylation of Astrin Regulates Its Kinetochore Function. J. Biol. Chem. 2016 Aug;291(34):17579-92
Chung HJ et al
2016/01/01
-
備考:
-
参照:
- No.: 47
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文献情報:
Redli PM et al. The Ska complex promotes Aurora B activity to ensure chromosome biorientation. J. Cell Biol. 2016 Oct;215(1):77-93
Redli PM et al
2016/01/01
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備考:
-
参照:
- No.: 48
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文献情報:
O'Connor A et al. Requirement for PLK1 kinase activity in the maintenance of a robust spindle assembly checkpoint. Biol Open 2015 Dec;5(1):11-9
O'Connor A et al
2015/01/01
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備考:
-
参照:
- No.: 49
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文献情報:
Zhu L et al. Mitotic Protein CSPP1 Interacts with CENP-H Protein to Coordinate Accurate Chromosome Oscillation in Mitosis. J. Biol. Chem. 2015 Nov;290(45):27053-66
Zhu L et al
2015/01/01
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備考:
-
参照:
- No.: 50
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文献情報:
Brouwers N et al. Role of Kif15 and its novel mitotic partner KBP in K-fiber dynamics and chromosome alignment. PLoS ONE 2017;12(4):e0174819
Brouwers N et al
2017/01/01
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備考:
Application: Immunocytochemistry/ Immunofluorescence, Reactivity: Human -
参照:
- No.: 51
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文献情報:
Kaczmarczyk A et al. CENP-W plays a role in maintaining bipolar spindle structure. PLoS ONE 2014;9(10):e106464
Kaczmarczyk A et al
2014/01/01
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備考:
Application: Immunocytochemistry/ Immunofluorescence, Reactivity: Human -
参照:
- No.: 52
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文献情報:
Janczyk PŁ et al. Mechanism of Ska Recruitment by Ndc80 Complexes to Kinetochores. Dev. Cell 2017 05;41(4):438-449.e4
Janczyk PŁ et al
2017/01/01
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備考:
Application: Immunocytochemistry/ Immunofluorescence, Proximity ligation assay, Reactivity: Human -
参照:
- No.: 53
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文献情報:
Niikura Y et al. SGT1-HSP90 complex is required for CENP-A deposition at centromeres. Cell Cycle 2017 Sep;16(18):1683-1694
Niikura Y et al
2017/01/01
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備考:
Application: Immunocytochemistry/ Immunofluorescence (ICC/IF), Reactivity: Human -
参照:
- No.: 54
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文献情報:
Park JE et al. The tobacco carcinogen NNK disturbs mitotic chromosome alignment by interrupting p53 targeting to the centrosome. Toxicol. Lett. 2017 Nov;281:110-118
Park JE et al
2017/01/01
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備考:
Application: Immunocytochemistry/ Immunofluorescence (ICC/IF), Reactivity: Human -
参照:
- No.: 55
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文献情報:
Lee M et al. The E2F activators control multiple mitotic regulators and maintain genomic integrity through Sgo1 and BubR1. Oncotarget 2017 Sep;8(44):77649-77672
Lee M et al
2017/01/01
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備考:
Application: Western Blot (WB), Reactivity: Human -
参照:
- No.: 56
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文献情報:
Petsalaki E et al. The ESCRT protein Chmp4c regulates mitotic spindle checkpoint signaling. J. Cell Biol. 2018 Mar;217(3):861-876
Petsalaki E et al
2018/01/01
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備考:
Application: Immunocytochemistry/ Immunofluorescence (ICC/IF), Reactivity: Human -
参照:
- No.: 57
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文献情報:
Zhou H et al. Cep57 is a Mis12-interacting kinetochore protein involved in kinetochore targeting of Mad1-Mad2. Nat Commun 2016 Jan;7:10151
Zhou H et al
2016/01/01
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備考:
Application: Immunocytochemistry/ Immunofluorescence (ICC/IF), Reactivity: Human -
参照:
- No.: 58
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文献情報:
Wolf PG et al. Studying meiotic cohesin in somatic cells reveals that Rec8-containing cohesin requires Stag3 to function and is regulated by Wapl and sororin. J. Cell. Sci. 2018 Jun;131(11)
Wolf PG et al
2018/01/01
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備考:
Application: Immunocytochemistry/ Immunofluorescence (ICC/IF), Reactivity: Human -
参照:
- No.: 59
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文献情報:
Petsalaki E et al. Chmp4c is required for stable kinetochore-microtubule attachments. Chromosoma 2018 Jul;
Petsalaki E et al
2018/01/01
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備考:
Application: Immunocytochemistry/ Immunofluorescence (ICC/IF), Reactivity: Human -
参照:
- No.: 60
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文献情報:
Janssen LME et al. Loss of Kif18A Results in Spindle Assembly Checkpoint Activation at Microtubule-Attached Kinetochores. Curr. Biol. 2018 Jul;
Janssen LME et al
2018/01/01
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備考:
Application: Immunocytochemistry/ Immunofluorescence (ICC/IF), Reactivity: Human -
参照:
- No.: 61
-
文献情報:
Fang Y et al. Preclinical activity of MBM-5 in gastrointestinal cancer by inhibiting NEK2 kinase activity. Oncotarget 2016 Nov;7(48):79327-79341
Fang Y et al
2016/01/01
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備考:
Application: Western Blot (WB), Reactivity: Human -
参照:
- No.: 62
-
文献情報:
Huis In 't Veld PJ et al. Molecular basis of outer kinetochore assembly on CENP-T. Elife 2016 12;5
Huis In 't Veld PJ et al
2016/01/01
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備考:
-
参照:
- No.: 63
-
文献情報:
Petrovic A et al. Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores. Cell 2016 11;167(4):1028-1040.e15
Petrovic A et al
2016/01/01
-
備考:
-
参照:
- No.: 64
-
文献情報:
Shirnekhi HK et al. Spindle assembly checkpoint signaling and sister chromatid cohesion are disrupted by HPV E6-mediated transformation. Mol. Biol. Cell 2017 Jul;28(15):2035-2041
Shirnekhi HK et al
2017/01/01
-
備考:
Application: Immunocytochemistry/ Immunofluorescence, Reactivity: Human -
参照:
- No.: 65
-
文献情報:
Nye J et al. HJURP antagonizes CENP-A mislocalization driven by the H3.3 chaperones HIRA and DAXX. PLoS ONE 2018;13(10):e0205948
Nye J et al
2018/01/01
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備考:
Application: Western Blot, Reactivity: Human -
参照:
- No.: 66
-
文献情報:
Hellmuth S et al. Local activation of mammalian separase in interphase promotes double-strand break repair and prevents oncogenic transformation. EMBO J. 2018 Nov;37(22)
Hellmuth S et al
2018/01/01
-
備考:
Application: Immunocytochemistry/ Immunofluorescence, Reactivity: Human -
参照:
- No.: 67
-
文献情報:
Hayward D et al. CDK1-CCNB1 creates a spindle checkpoint-permissive state by enabling MPS1 kinetochore localization. J. Cell Biol. 2019 Apr;218(4):1182-1199
Hayward D et al
2019/01/01
-
備考:
Application: Immunocytochemistry/ Immunofluorescence, Reactivity: Human -
参照:
- No.: 68
-
文献情報:
Malaby HL et al. KIF18A's neck linker permits navigation of microtubule-bound obstacles within the mitotic spindle. Life Sci Alliance 2019 Feb;2(1)
Malaby HL et al
2019/01/01
-
備考:
Application: Immunocytochemistry/ Immunofluorescence, Reactivity: Human -
参照:
- No.: 69
-
文献情報:
Alfonso-P辿rez T et al. MAD1-dependent recruitment of CDK1-CCNB1 to kinetochores promotes spindle checkpoint signaling. J. Cell Biol. 2019 Apr;218(4):1108-1117
Alfonso-P辿rez T et al
2019/01/01
-
備考:
-
参照:
- No.: 70
-
文献情報:
Chuang SH et al. Discovery of T-1101 tosylate as a first-in-class clinical candidate for Hec1/Nek2 inhibition in cancer therapy. Eur J Med Chem 2020 Apr;191:112118
Chuang SH et al
2020/01/01
-
備考:
-
参照:
- No.: 71
-
文献情報:
Kim S et al. PRMT6-mediated H3R2me2a guides Aurora B to chromosome arms for proper chromosome segregation. Nat Commun 2020 01;11(1):612
Kim S et al
2020/01/01
-
備考:
-
参照:
- No.: 72
-
文献情報:
Gwon D et al. c-Cbl Acts as an E3 Ligase Against DDA3 for Spindle Dynamics and Centriole Duplication during Mitosis. Mol. Cells 2019 Dec;42(12):840-849
Gwon D et al
2019/01/01
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備考:
-
参照:
- No.: 73
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文献情報:
Asai Y et al. Aurora B kinase activity is regulated by SET/TAF1 on Sgo2 at the inner centromere. J. Cell Biol. 2019 10;218(10):3223-3236
Asai Y et al
2019/01/01
-
備考:
-
参照:
- No.: 74
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文献情報:
Kim S et al. Bisphenol A disrupts mitotic progression via disturbing spindle attachment to kinetochore and centriole duplication in cancer cell lines. Toxicol In Vitro 2019 Sep;59:115-125
Kim S et al
2019/01/01
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備考:
-
参照:
- No.: 75
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文献情報:
Li W et al. A methylation-phosphorylation switch determines Plk1 kinase activity and function in DNA damage repair. Sci Adv 2019 03;5(3):eaau7566
Li W et al
2019/01/01
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備考:
-
参照:
- No.: 76
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文献情報:
Malaby HLH et al. Kinesin-binding protein ensures accurate chromosome segregation by buffering KIF18A and KIF15. J. Cell Biol. 2019 Apr;218(4):1218-1234
Malaby HLH et al
2019/01/01
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備考:
-
参照:
- No.: 77
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文献情報:
Ferrara M et al. Small molecules targeted to the microtubule-Hec1 interaction inhibit cancer cell growth through microtubule stabilization. Oncogene 2018 01;37(2):231-240
Ferrara M et al
2018/01/01
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備考:
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