Anti-Human IL-6 MAb (Clone 6708)

データシート※最新のデータシートでない場合があります

• 商品コード：MAB206-SP
• メーカー：RSD
• 包装：25μg
• 価格： ¥28,000
• 在庫：無(未発注)

マイリストに追加 マイリストに追加済

• No.： 1
• 文献情報：
  Gorchs L et al. The vitamin D analogue calcipotriol promotes an anti-tumorigenic phenotype of human pancreatic CAFs but reduces T cell mediated immunity. Sci Rep 2020 10;10(1):17444
  Gorchs L et al
  2020/01/01
  
• 備考：
  Species: Human, Applications: ELISA Capture
• 参照：
  

• No.： 2
• 文献情報：
  Sun X et al. Tumor suppressor HIC1 is synergistically compromised by cancer-associated fibroblasts and tumor cells through the IL-6/pSTAT3 axis in breast cancer. BMC Cancer 2019 Dec;19(1):1180
  Sun X et al
  2019/01/01
  
• 備考：
  Species: Human, Applications: ELISA Capture
• 参照：
  

• No.： 3
• 文献情報：
  Bernau K et al. Interleukin-1α Is a Critical Mediator of the Response of Human Bronchial Fibroblasts to Eosinophilic Inflammation. Cells 2021 03;10(3)
  Bernau K et al
  2021/01/01
  
• 備考：
  Species: Human, Applications: ELISA Capture
• 参照：
  

• No.： 4
• 文献情報：
  Stumpf A et al. Hydrogel based protein biochip for parallel detection of biomarkers for diagnosis of a Systemic Inflammatory Response Syndrome (SIRS) in human serum. PLoS One 2019;14(12):e0225525
  Stumpf A et al
  2019/01/01
  
• 備考：
  Species: Human, Applications: ELISA Capture
• 参照：
  

• No.： 5
• 文献情報：
  Pan T et al. Shikonin blocks human lung adenocarcinoma cell migration and invasion in the inflammatory microenvironment via the IL‑6/STAT3 signaling pathway. Oncol Rep 2020 Sep;44(3):1049-1063
  Pan T et al
  2020/01/01
  
• 備考：
  Species: Human, Applications: b/n
• 参照：
  

• No.： 6
• 文献情報：
  Śliwińska-Mossoń M et al. Diabetes mellitus secondary to pancreatic diseases (type 3c): The effect of smoking on the exocrine-endocrine interactions of the pancreas. Diab Vasc Dis Res 2018 May;15(3):243-259
  Śliwińska-Mossoń M et al
  2018/01/01
  
• 備考：
  Species: Human, Applications: IHC
• 参照：
  

• No.： 7
• 文献情報：
  Zheng M et al. Interleukin-6 participates in human pancreatic stellate cell activation and collagen I production via TGF-β1/Smad pathway. Cytokine 2021 07;143:155536
  Zheng M et al
  2021/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 8
• 文献情報：
  Hook JS et al. <i>Mycobacterium tuberculosis</i> Lipoarabinomannan Activates Human Neutrophils via a TLR2/1 Mechanism Distinct from Pam₃CSK₄. J Immunol 2020 02;204(3):671-681
  Hook JS et al
  2020/01/01
  
• 備考：
  Species: Human, Applications: ELISA Capture
• 参照：
  

• No.： 9
• 文献情報：
  Liotta F et al. Toll-like receptors 3 and 4 are expressed by human bone marrow-derived mesenchymal stem cells and can inhibit their T-cell modulatory activity by impairing Notch signaling. Stem Cells 2008 Jan;26(1):279-89
  Liotta F et al
  2008/01/01
  
• 備考：
  Species: Human, Applications: ELISA Development
• 参照：
  

• No.： 10
• 文献情報：
  Gril B et al. Reactive astrocytic S1P3 signaling modulates the blood-tumor barrier in brain metastases. Nat Commun 2018 Jul;9(1):2705
  Gril B et al
  2018/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 11
• 文献情報：
  Takeuchi S et al. Chemotherapy-Derived Inflammatory Responses Accelerate the Formation of Immunosuppressive Myeloid Cells in the Tissue Microenvironment of Human Pancreatic Cancer. Cancer Res. 2015 Jul;75(13):2629-40
  Takeuchi S et al
  2015/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 12
• 文献情報：
  Matsubara K et al. Secreted ectodomain of sialic acid-binding Ig-like lectin-9 and monocyte chemoattractant protein-1 promote recovery after rat spinal cord injury by altering macrophage polarity. J. Neurosci. 2015 Feb;35(6):2452-64
  Matsubara K et al
  2015/01/01
  
• 備考：
  Species: Rat, Applications: Neutralization
• 参照：
  

• No.： 13
• 文献情報：
  Harrison ML et al. Tumor necrosis factor alpha as a new target for renal cell carcinoma: two sequential phase II trials of infliximab at standard and high dose. J. Clin. Oncol. 2007 Oct;25(29):4542-9
  Harrison ML et al
  2007/01/01
  
• 備考：
  Species: Human, Applications: IHC-Fr
• 参照：
  

• No.： 14
• 文献情報：
  Brencicova E et al. Interleukin-10 and prostaglandin E2 have complementary but distinct suppressive effects on Toll-like receptor-mediated dendritic cell activation in ovarian carcinoma. PLoS ONE 2017;12(4):e0175712
  Brencicova E et al
  2017/01/01
  
• 備考：
  Species: Human, Applications: ELISA Development (Capture)
• 参照：
  

• No.： 15
• 文献情報：
  Filer A et al. Differential survival of leukocyte subsets mediated by synovial, bone marrow, and skin fibroblasts: site-specific versus activation-dependent survival of T cells and neutrophils. Arthritis Rheum. 2006 Jul;54(7):2096-108
  Filer A et al
  2006/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 16
• 文献情報：
  Kambas K et al. C5a and TNF-alpha up-regulate the expression of tissue factor in intra-alveolar neutrophils of patients with the acute respiratory distress syndrome. J. Immunol. 2008 Jun;180(11):7368-75
  Kambas K et al
  2008/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 17
• 文献情報：
  Logue SE et al. Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy. Nat Commun 2018 08;9(1):3267
  Logue SE et al
  2018/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 18
• 文献情報：
  Pav坦n L et al. Th2 cytokine response in Major Depressive Disorder patients before treatment. J. Neuroimmunol. 2006 Mar;172(1-2):156-65
  Pav坦n L et al
  2006/01/01
  
• 備考：
  Species: Human, Applications: ELISA Development
• 参照：
  

• No.： 19
• 文献情報：
  Holst RM et al. Interleukin-6 and interleukin-8 in cervical fluid in a population of Swedish women in preterm labor: relationship to microbial invasion of the amniotic fluid, intra-amniotic inflammation, and preterm delivery. Acta Obstet Gynecol Scand 200
  Holst RM et al
  2005/01/01
  
• 備考：
  Species: Human, Applications: ELISA Development
• 参照：
  

• No.： 20
• 文献情報：
  Hooda J et al. Early Loss of Histone H2B Monoubiquitylation Alters Chromatin Accessibility and Activates Key Immune Pathways That Facilitate Progression of Ovarian Cancer. Cancer Res. 2019 02;79(4):760-772
  Hooda J et al
  2019/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 21
• 文献情報：
  Hollins F et al. Human airway smooth muscle promotes human lung mast cell survival, proliferation, and constitutive activation: cooperative roles for CADM1, stem cell factor, and IL-6. J. Immunol. 2008 Aug;181(4):2772-80
  Hollins F et al
  2008/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 22
• 文献情報：
  Rolvering C et al. The PD-L1- and IL6-mediated dampening of the IL27/STAT1 anticancer responses are prevented by &#x3B1;-PD-L1 or &#x3B1;-IL6 antibodies. J. Leukoc. Biol. 2018 Jul;
  Rolvering C et al
  2018/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 23
• 文献情報：
  Touil H et al. Human central nervous system astrocytes support survival and activation of B cells: implications for MS pathogenesis. J Neuroinflammation 2018 Apr;15(1):114
  Touil H et al
  2018/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 24
• 文献情報：
  Liu WL et al. Epstein-Barr virus infection induces indoleamine 2,3-dioxygenase expression in human monocyte-derived macrophages through p38/mitogen-activated protein kinase and NF-&#x3BA;B pathways: impairment in T cell functions. J. Virol. 2014 Jun;88(12
  Liu WL et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 25
• 文献情報：
  Mace TA et al. Pancreatic cancer-associated stellate cells promote differentiation of myeloid-derived suppressor cells in a STAT3-dependent manner. Cancer Res. 2013 May;73(10):3007-18
  Mace TA et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 26
• 文献情報：
  Mar AC et al. Interleukin-1 Receptor Type 2 Acts with c-Fos to Enhance the Expression of Interleukin-6 and Vascular Endothelial Growth Factor A in Colon Cancer Cells and Induce Angiogenesis. J. Biol. Chem. 2015 Sep;290(36):22212-24
  Mar AC et al
  2015/01/01
  
• 備考：
  Species: Mouse, Applications: Neutralization
• 参照：
  

• No.： 27
• 文献情報：
  McLoughlin RM et al. Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation. J. Clin. Invest. 2003 Aug;112(4):598-607
  McLoughlin RM et al
  2003/01/01
  
• 備考：
  Species: Human, Applications: ELISA Development
• 参照：
  

• No.： 28
• 文献情報：
  Hong YS et al. Measurement of interleukin-33 (IL-33) and IL-33 receptors (sST2 and ST2L) in patients with rheumatoid arthritis. J. Korean Med. Sci. 2011 Sep;26(9):1132-9
  Hong YS et al
  2011/01/01
  
• 備考：
  Species: Human, Applications: ELISA Development
• 参照：
  

• No.： 29
• 文献情報：
  Chimen M et al. Monocyte Subsets Coregulate Inflammatory Responses by Integrated Signaling through TNF and IL-6 at the Endothelial Cell Interface. J. Immunol. 2017 Apr;198(7):2834-2843
  Chimen M et al
  2017/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 30
• 文献情報：
  Wang D et al. Maslinic acid suppresses the growth of human gastric cells by inducing apoptosis via inhibition of the interleukin-6 mediated Janus kinase/signal transducer and activator of transcription 3 signaling pathway. Oncol Lett 2017 Jun;13(6):4875-4
  Wang D et al
  2017/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 31
• 文献情報：
  Ortiz-Montero P et al. Senescence-associated IL-6 and IL-8 cytokines induce a self- and cross-reinforced senescence/inflammatory milieu strengthening tumorigenic capabilities in the MCF-7 breast cancer cell line. Cell Commun. Signal 2017 05;15(1):17
  Ortiz-Montero P et al
  2017/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 32
• 文献情報：
  Hess S et al. The reprogrammed host: Chlamydia trachomatis-induced up-regulation of glycoprotein 130 cytokines, transcription factors, and antiapoptotic genes. Arthritis Rheum. 2001 Oct;44(10):2392-401
  Hess S et al
  2001/01/01
  
• 備考：
  Species: Human, Applications: ELISA Development
• 参照：
  

• No.： 33
• 文献情報：
  Raimbourg J et al. Sensitization of EGFR Wild-Type Non-Small Cell Lung Cancer Cells to EGFR-Tyrosine Kinase Inhibitor Erlotinib. Mol. Cancer Ther. 2017 Aug;16(8):1634-1644
  Raimbourg J et al
  2017/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 34
• 文献情報：
  Nandana S et al. Bone Metastasis of Prostate Cancer Can Be Therapeutically Targeted at the TBX2-WNT Signaling Axis. Cancer Res. 2017 Mar;77(6):1331-1344
  Nandana S et al
  2017/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 35
• 文献情報：
  Mitchell CM et al. Bacterial vaginosis, not HIV, is primarily responsible for increased vaginal concentrations of proinflammatory cytokines. AIDS Res. Hum. Retroviruses 2008 May;24(5):667-71
  Mitchell CM et al
  2008/01/01
  
• 備考：
  Species: Human, Applications: ELISA Development
• 参照：
  

• No.： 36
• 文献情報：
  Hurst SM et al. Secretion of oncostatin M by infiltrating neutrophils: regulation of IL-6 and chemokine expression in human mesothelial cells. J. Immunol. 2002 Nov;169(9):5244-51
  Hurst SM et al
  2002/01/01
  
• 備考：
  Species: Human, Applications: ELISA Development
• 参照：
  

• No.： 37
• 文献情報：
  Aliahmadi E et al. TLR2-activated human langerhans cells promote Th17 polarization via IL-1beta, TGF-beta and IL-23. Eur. J. Immunol. 2009 May;39(5):1221-30
  Aliahmadi E et al
  2009/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 38
• 文献情報：
  Arnold R et al. Peroxisome proliferator-activated receptor-gamma agonists inhibit respiratory syncytial virus-induced expression of intercellular adhesion molecule-1 in human lung epithelial cells. Immunology 2007 May;121(1):71-81
  Arnold R et al
  2007/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 39
• 文献情報：
  Todd J et al. Reference range and short- and long-term biological variation of interleukin (IL)-6, IL-17A and tissue necrosis factor-alpha using high sensitivity assays. Cytokine 2013 Dec;64(3):660-5
  Todd J et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: ELISA Development
• 参照：
  

• No.： 40
• 文献情報：
  Zhao X et al. Pre-analytical effects of blood sampling and handling in quantitative immunoassays for rheumatoid arthritis. J. Immunol. Methods 2012 Apr;378(1-2):72-80
  Zhao X et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ELISA Development
• 参照：
  

• No.： 41
• 文献情報：
  Pathak JL et al. CXCL8 and CCL20 Enhance Osteoclastogenesis via Modulation of Cytokine Production by Human Primary Osteoblasts. PLoS ONE 2015;10(6):e0131041
  Pathak JL et al
  2015/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 42
• 文献情報：
  Kuravi SJ et al. Podocytes regulate neutrophil recruitment by glomerular endothelial cells via IL-6-mediated crosstalk. J. Immunol. 2014 Jul;193(1):234-43
  Kuravi SJ et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 43
• 文献情報：
  Galland S et al. Tumor-Derived Mesenchymal Stem Cells Use Distinct Mechanisms to Block the Activity of Natural Killer Cell Subsets. Cell Rep 2017 Sep;20(12):2891-2905
  Galland S et al
  2017/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 44
• 文献情報：
  Zhou J et al. Interleukin&#x2011;6 induces an epithelial&#x2011;mesenchymal transition phenotype in human adamantinomatous craniopharyngioma cells and promotes tumor cell migration. Mol Med Rep 2017 Jun;15(6):4123-4131
  Zhou J et al
  2017/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 45
• 文献情報：
  Hu H et al. Noninvasive detection of acute and chronic injuries in human renal transplant by elevation of multiple cytokines/chemokines in urine. Transplantation 2009 Jun;87(12):1814-20
  Hu H et al
  2009/01/01
  
• 備考：
  Species: Human, Applications: Antibody Array Development
• 参照：
  

• No.： 46
• 文献情報：
  Kuranda K et al. Exposure to wild-type AAV drives distinct capsid immunity profiles in humans. J. Clin. Invest. 2018 Dec;128(12):5267-5279
  Kuranda K et al
  2018/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 47
• 文献情報：
  Voltolini C et al. Urocortin 2 role in placental and myometrial inflammatory mechanisms at parturition. Endocrinology 2015 Feb;156(2):670-9
  Voltolini C et al
  2015/01/01
  
• 備考：
  Species: Human, Applications: ELISA Development (Capture)
• 参照：
  

• No.： 48
• 文献情報：
  Hsia HC et al. Cytosolic DNA Promotes Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation by TANK-binding Kinase 1 (TBK1) to Restrain STAT3 Activity. J. Biol. Chem. 2017 Mar;292(13):5405-5417
  Hsia HC et al
  2017/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 49
• 文献情報：
  Wu W et al. Resistance of human alveolar macrophages to Bacillus anthracis lethal toxin. J. Immunol. 2009 Nov;183(9):5799-806
  Wu W et al
  2009/01/01
  
• 備考：
  Species: Human, Applications: ELISA Development
• 参照：
  

• No.： 50
• 文献情報：
  Chehboun S et al. Epstein-Barr virus-induced gene 3 (EBI3) can mediate IL-6 trans-signaling. J. Biol. Chem. 2017 Apr;292(16):6644-6656
  Chehboun S et al
  2017/01/01
  
• 備考：
  Species: Mouse, Applications: Neutralization
• 参照：
  

• No.： 51
• 文献情報：
  Munir H et al. Adipogenic Differentiation of Mesenchymal Stem Cells Alters Their Immunomodulatory Properties in a Tissue-Specific Manner. Stem Cells 2017 Jun;35(6):1636-1646
  Munir H et al
  2017/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 52
• 文献情報：
  Kurago ZB et al. Lipopolysaccharide-squamous cell carcinoma-monocyte interactions induce cancer-supporting factors leading to rapid STAT3 activation. Head Neck Pathol 2008 Mar;2(1):1-12
  Kurago ZB et al
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• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 53
• 文献情報：
  Tso GH et al. Phagocytosis of apoptotic cells modulates mesenchymal stem cells osteogenic differentiation to enhance IL-17 and RANKL expression on CD4+ T cells. Stem Cells 2010 May;28(5):939-54
  Tso GH et al
  2010/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 54
• 文献情報：
  Copeland S et al. Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines. J. Immunol. Methods 2004 Jan;284(1-2):99-106
  Copeland S et al
  2004/01/01
  
• 備考：
  Species: Human, Applications: Array Development
• 参照：
  

• No.： 55
• 文献情報：
  Lv R et al. IL-33 Attenuates Sepsis by Inhibiting IL-17 Receptor Signaling through Upregulation of SOCS3. Cell. Physiol. Biochem. 2017;42(5):1961-1972
  Lv R et al
  2017/01/01
  
• 備考：
  Species: Human, Applications: ELISA Development (Capture)
• 参照：
  

• No.： 56
• 文献情報：
  Nold MF et al. Endogenous IL-32 controls cytokine and HIV-1 production. J. Immunol. 2008 Jul;181(1):557-65
  Nold MF et al
  2008/01/01
  
• 備考：
  Species: Human, Applications: Electrochemiluminescent Assay
• 参照：
  

• No.： 57
• 文献情報：
  Henry CM et al. Caspase-8 Acts in a Non-enzymatic Role as a Scaffold for Assembly of a Pro-inflammatory &quot;FADDosome&quot; Complex upon TRAIL Stimulation. Mol. Cell 2017 Feb;65(4):715-729.e5
  Henry CM et al
  2017/01/01
  
• 備考：
  Species: Human, Applications: ICC
• 参照：
  

• No.： 58
• 文献情報：
  Phillips TM. Rapid analysis of inflammatory cytokines in cerebrospinal fluid using chip-based immunoaffinity electrophoresis. Electrophoresis 2004 Jun;25(10-11):1652-9
  Phillips TM
  2004/01/01
  
• 備考：
  Species: Human, Applications: Affinity Chromatography
• 参照：
  

• No.： 59
• 文献情報：
  Micera A et al. Age-Related Changes to Human Tear Composition. Invest. Ophthalmol. Vis. Sci. 2018 Apr;59(5):2024-2031
  Micera A et al
  2018/01/01
  
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  Species: Human, Applications:
• 参照：
  

• No.： 60
• 文献情報：
  Mozaffarian D et al. trans fatty acids and systemic inflammation in heart failure. Am. J. Clin. Nutr. 2004 Dec;80(6):1521-5
  Mozaffarian D et al
  2004/01/01
  
• 備考：
  Species: Human, Applications: ELISA Development
• 参照：
  

• No.： 61
• 文献情報：
  Todd J et al. Ultrasensitive flow-based immunoassays using single-molecule counting. Clin. Chem. 2007 Nov;53(11):1990-5
  Todd J et al
  2007/01/01
  
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  Species: Human, Applications: ELISA Development
• 参照：
  

• No.： 62
• 文献情報：
  Nicolaidou V et al. Monocytes induce STAT3 activation in human mesenchymal stem cells to promote osteoblast formation. PLoS ONE 2012;7(7):e39871
  Nicolaidou V et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 63
• 文献情報：
  Munir H et al. Comparative Ability of Mesenchymal Stromal Cells from Different Tissues to Limit Neutrophil Recruitment to Inflamed Endothelium. PLoS ONE 2016;11(5):e0155161
  Munir H et al
  2016/01/01
  
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  Species: Human, Applications: Neutralization
• 参照：
  

• No.： 64
• 文献情報：
  Osei-Kumah A et al. Maternal and cord plasma cytokine and chemokine profile in pregnancies complicated by asthma. Cytokine 2008 Aug;43(2):187-93
  Osei-Kumah A et al
  2008/01/01
  
• 備考：
  Species: Human, Applications: ELISA Development
• 参照：
  

• No.： 65
• 文献情報：
  Zepp JA et al. Protection from RNA and DNA viruses by IL-32. J. Immunol. 2011 Apr;186(7):4110-8
  Zepp JA et al
  2011/01/01
  
• 備考：
  Species: Human, Applications: Electrochemiluminescent Assay
• 参照：
  

• No.： 66
• 文献情報：
  Mok J et al. Digital microfluidic assay for protein detection. Proc. Natl. Acad. Sci. U.S.A. 2014 Feb;111(6):2110-5
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• 備考：
  Species: Human, Applications: Microfluidic Assay
• 参照：
  

• No.： 67
• 文献情報：
  Uchibori T et al. IL-6 trans-signaling is another pathway to upregulate Osteopontin. Cytokine 2017 Feb;90:88-95
  Uchibori T et al
  2017/01/01
  
• 備考：
  Species: Human, Applications: Neutralization
• 参照：