価格表

在庫・価格 : 2025年10月07日 05時05分 現在

商品名 商品コード メーカー 包装 価格 在庫 リスト
Anti-Human CXCR4 (Fusin) MAb (Clone 12G5)
データシート※最新のデータシートでない場合があります
MAB170-SP RSDアールアンドディー システムズ
R&D Systems, Inc.
25 μg ¥30,000
(未発注)
追加

在庫・価格 : 2025年10月07日 05時05分 現在

Anti-Human CXCR4 (Fusin) MAb (Clone 12G5)

  • 商品コード:MAB170-SP
  • メーカー:RSD
  • 包装:25μg
  • 価格: ¥30,000
  • 在庫:無(未発注)
使用文献
No. 文献情報 備考 参照
1 Armani-Tourret M et al. Mechanisms of HIV-1 evasion to the antiviral activity of chemokine CXCL12 indicate potential links with pathogenesis. PLoS Pathog 2021 04;17(4):e1009526
Armani-Tourret M et al
2021/01/01
Species: Human, Applications: Binding Assay PubMed
2 Ieran嘆 C et al. CXCL12 loaded-dermal filler captures CXCR4 expressing melanoma circulating tumor cells. Cell Death Dis 2019 07;10(8):562
Ieran嘆 C et al
2019/01/01
Species: Human, Applications: ICC PubMed
3 Zsiros E et al. The Ovarian Cancer Chemokine Landscape Is Conducive to Homing of Vaccine-Primed and CD3/CD28-Costimulated T Cells Prepared for Adoptive Therapy. Clin. Cancer Res. 2015 Jun;21(12):2840-50
Zsiros E et al
2015/01/01
Species: Human, Applications: Neutralization PubMed
4 Griffiths K et al. i-bodies, Human Single Domain Antibodies That Antagonize Chemokine Receptor CXCR4. J. Biol. Chem. 2016 Jun;291(24):12641-57
Griffiths K et al
2016/01/01
Species: Human, Applications: Bioassay PubMed
5 Hartl D et al. Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. J. Immunol. 2008 Dec;181(11):8053-67
Hartl D et al
2008/01/01
Species: Human, Applications: Flow Cytometry PubMed
6 McLean AB et al. Activin a efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed. Stem Cells 2007 Jan;25(1):29-38
McLean AB et al
2007/01/01
Species: Human, Applications: Flow Cytometry PubMed
7 Patrussi L et al. Enhanced Chemokine Receptor Recycling and Impaired S1P1 Expression Promote Leukemic Cell Infiltration of Lymph Nodes in Chronic Lymphocytic Leukemia. Cancer Res. 2015 Oct;75(19):4153-63
Patrussi L et al
2015/01/01
Species: Human, Applications: Flow Cytometry PubMed
8 Yasumoto K et al. The EGFR ligands amphiregulin and heparin-binding egf-like growth factor promote peritoneal carcinomatosis in CXCR4-expressing gastric cancer. Clin. Cancer Res. 2011 Jun;17(11):3619-30
Yasumoto K et al
2011/01/01
Species: Human, Applications: Neutralization PubMed
9 Narducci MG et al. Skin homing of SAczary cells involves SDF-1-CXCR4 signaling and down-regulation of CD26/dipeptidylpeptidase IV. Blood 2006 Feb;107(3):1108-15
Narducci MG et al
2006/01/01
Species: Human, Applications: IHC PubMed
10 Kaminski A et al. Endothelial NOS is required for SDF-1alpha/CXCR4-mediated peripheral endothelial adhesion of c-kit+ bone marrow stem cells. Lab. Invest. 2008 Jan;88(1):58-69
Kaminski A et al
2008/01/01
Species: Mouse, Applications: Neutralization PubMed
11 Li S et al. Activation of MAPK signaling by CXCR7 leads to enzalutamide resistance in prostate cancer. Cancer Res. 2019 Apr;
Li S et al
2019/01/01
Species: Human, Applications: Western Blot PubMed
12 Bug G et al. Rho family small GTPases control migration of hematopoietic progenitor cells into multicellular spheroids of bone marrow stroma cells. J. Leukoc. Biol. 2002 Oct;72(4):837-45
Bug G et al
2002/01/01
Species: Human, Applications: ICC PubMed
13 Deiva K et al. CCR5-, DC-SIGN-dependent endocytosis and delayed reverse transcription after human immunodeficiency virus type 1 infection in human astrocytes. AIDS Res. Hum. Retroviruses 2006 Nov;22(11):1152-61
Deiva K et al
2006/01/01
Species: Human, Applications: Neutralization PubMed
14 Tavor S et al. CXCR4 regulates migration and development of human acute myelogenous leukemia stem cells in transplanted NOD/SCID mice. Cancer Res. 2004 Apr;64(8):2817-24
Tavor S et al
2004/01/01
Species: Human, Applications: ICC PubMed
15 Lisignoli G et al. Hyaluronan-based polymer scaffold modulates the expression of inflammatory and degradative factors in mesenchymal stem cells: Involvement of Cd44 and Cd54. J. Cell. Physiol. 2006 May;207(2):364-73
Lisignoli G et al
2006/01/01
Species: Human, Applications: ICC PubMed
16 Honczarenko M et al. CCR5-binding chemokines modulate CXCL12 (SDF-1)-induced responses of progenitor B cells in human bone marrow through heterologous desensitization of the CXCR4 chemokine receptor. Blood 2002 Oct;100(7):2321-9
Honczarenko M et al
2002/01/01
Species: Human, Applications: Flow Cytometry PubMed
17 Kobune M et al. Interaction with human stromal cells enhances CXCR4 expression and engraftment of cord blood Lin(-)CD34(-) cells. Exp. Hematol. 2008 Sep;36(9):1121-31
Kobune M et al
2008/01/01
Species: Human, Applications: Neutralization PubMed
18 Zhang Y et al. Intracellular localization and constitutive endocytosis of CXCR4 in human CD34+ hematopoietic progenitor cells. Stem Cells 2004;22(6):1015-29
Zhang Y et al
2004/01/01
Species: Human, Applications: Flow Cytometry PubMed
19 Dinkel BA et al. GRK2 mediates TCR-induced transactivation of CXCR4 and TCR-CXCR4 complex formation that drives PI3Kγ/PREX1 signaling and T cell cytokine secretion. J. Biol. Chem. 2018 Sep;293(36):14022-14039
Dinkel BA et al
2018/01/01
Species: Human, Applications: Flow Cytometry PubMed
20 Shankar V et al. Mesenchymal stromal cell secretome up-regulates 47 kDa CXCR4 expression, and induce invasiveness in neuroblastoma cell lines. PLoS ONE 2015;10(3):e0120069
Shankar V et al
2015/01/01
Species: Human, Applications: Neutralization PubMed
21 Schneider P et al. Is high expression of the chemokine receptor CXCR-4 of predictive value for early relapse in childhood acute lymphoblastic leukaemia? Br. J. Haematol. 2002 Nov;119(2):579-80
Schneider P et al
2002/01/01
Species: Human, Applications: ICC PubMed
22 Park BH et al. An isoform of C/EBPβ, LIP, regulates expression of the chemokine receptor CXCR4 and modulates breast cancer cell migration. J. Biol. Chem. 2013 Oct;288(40):28656-67
Park BH et al
2013/01/01
Species: Human, Applications: Neutralization PubMed
23 Ao M et al. Cross-talk between paracrine-acting cytokine and chemokine pathways promotes malignancy in benign human prostatic epithelium. Cancer Res. 2007 May;67(9):4244-53
Ao M et al
2007/01/01
Species: Human, Applications: Neutralization PubMed
24 Mills SC et al. Rac1 plays a role in CXCL12 but not CCL3-induced chemotaxis and Rac1 GEF inhibitor NSC23766 has off target effects on CXCR4. Cell. Signal. 2018 Jan;42:88-96
Mills SC et al
2018/01/01
Species: Human, Applications: Flow Cytometry PubMed
25 Lawrence DM et al. Human immunodeficiency virus type 1 infection of human brain-derived progenitor cells. J. Virol. 2004 Jul;78(14):7319-28
Lawrence DM et al
2004/01/01
Species: Human, Applications: Flow Cytometry PubMed
26 Huber TB et al. Expression of functional CCR and CXCR chemokine receptors in podocytes. J. Immunol. 2002 Jun;168(12):6244-52
Huber TB et al
2002/01/01
Species: Human, Applications: IHC-Fr PubMed
27 Wu WL et al. Δ20 IFITM2 differentially restricts X4 and R5 HIV-1. Proc. Natl. Acad. Sci. U.S.A. 2017 07;114(27):7112-7117
Wu WL et al
2017/01/01
Species: Human, Applications: Flow Cytometry PubMed
28 Lin YL et al. Mesenchymal Stem Cells Ameliorate Atherosclerotic Lesions via Restoring Endothelial Function. Stem Cells Transl Med 2015 Jan;4(1):44-55
Lin YL et al
2015/01/01
Species: Human, Applications: Neutralization PubMed
29 Han Y et al. CXCR7 maintains osteosarcoma invasion after CXCR4 suppression in bone marrow microenvironment. Tumour Biol. 2017 May;39(5):1010428317701631
Han Y et al
2017/01/01
Species: Human, Applications: Neutralization PubMed
30 Lopez-Haber C et al. Heregulin/ErbB3 Signaling Enhances CXCR4-Driven Rac1 Activation and Breast Cancer Cell Motility via Hypoxia-Inducible Factor 1α. Mol. Cell. Biol. 2016 Aug;36(15):2011-26
Lopez-Haber C et al
2016/01/01
Species: Human, Applications: Neutralization Control PubMed
31 Wescott MP et al. Signal transmission through the CXC chemokine receptor 4 (CXCR4) transmembrane helices. Proc. Natl. Acad. Sci. U.S.A. 2016 Aug;113(35):9928-33
Wescott MP et al
2016/01/01
Species: Human, Applications: IHC-Fr PubMed
  • No.: 1
  • 文献情報:
    Armani-Tourret M et al. Mechanisms of HIV-1 evasion to the antiviral activity of chemokine CXCL12 indicate potential links with pathogenesis. PLoS Pathog 2021 04;17(4):e1009526
    Armani-Tourret M et al
    2021/01/01
  • 備考:
    Species: Human, Applications: Binding Assay
  • 参照:
    PubMed
  • No.: 2
  • 文献情報:
    Ieran嘆 C et al. CXCL12 loaded-dermal filler captures CXCR4 expressing melanoma circulating tumor cells. Cell Death Dis 2019 07;10(8):562
    Ieran嘆 C et al
    2019/01/01
  • 備考:
    Species: Human, Applications: ICC
  • 参照:
    PubMed
  • No.: 3
  • 文献情報:
    Zsiros E et al. The Ovarian Cancer Chemokine Landscape Is Conducive to Homing of Vaccine-Primed and CD3/CD28-Costimulated T Cells Prepared for Adoptive Therapy. Clin. Cancer Res. 2015 Jun;21(12):2840-50
    Zsiros E et al
    2015/01/01
  • 備考:
    Species: Human, Applications: Neutralization
  • 参照:
    PubMed
  • No.: 4
  • 文献情報:
    Griffiths K et al. i-bodies, Human Single Domain Antibodies That Antagonize Chemokine Receptor CXCR4. J. Biol. Chem. 2016 Jun;291(24):12641-57
    Griffiths K et al
    2016/01/01
  • 備考:
    Species: Human, Applications: Bioassay
  • 参照:
    PubMed
  • No.: 5
  • 文献情報:
    Hartl D et al. Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. J. Immunol. 2008 Dec;181(11):8053-67
    Hartl D et al
    2008/01/01
  • 備考:
    Species: Human, Applications: Flow Cytometry
  • 参照:
    PubMed
  • No.: 6
  • 文献情報:
    McLean AB et al. Activin a efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed. Stem Cells 2007 Jan;25(1):29-38
    McLean AB et al
    2007/01/01
  • 備考:
    Species: Human, Applications: Flow Cytometry
  • 参照:
    PubMed
  • No.: 7
  • 文献情報:
    Patrussi L et al. Enhanced Chemokine Receptor Recycling and Impaired S1P1 Expression Promote Leukemic Cell Infiltration of Lymph Nodes in Chronic Lymphocytic Leukemia. Cancer Res. 2015 Oct;75(19):4153-63
    Patrussi L et al
    2015/01/01
  • 備考:
    Species: Human, Applications: Flow Cytometry
  • 参照:
    PubMed
  • No.: 8
  • 文献情報:
    Yasumoto K et al. The EGFR ligands amphiregulin and heparin-binding egf-like growth factor promote peritoneal carcinomatosis in CXCR4-expressing gastric cancer. Clin. Cancer Res. 2011 Jun;17(11):3619-30
    Yasumoto K et al
    2011/01/01
  • 備考:
    Species: Human, Applications: Neutralization
  • 参照:
    PubMed
  • No.: 9
  • 文献情報:
    Narducci MG et al. Skin homing of SAczary cells involves SDF-1-CXCR4 signaling and down-regulation of CD26/dipeptidylpeptidase IV. Blood 2006 Feb;107(3):1108-15
    Narducci MG et al
    2006/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 10
  • 文献情報:
    Kaminski A et al. Endothelial NOS is required for SDF-1alpha/CXCR4-mediated peripheral endothelial adhesion of c-kit+ bone marrow stem cells. Lab. Invest. 2008 Jan;88(1):58-69
    Kaminski A et al
    2008/01/01
  • 備考:
    Species: Mouse, Applications: Neutralization
  • 参照:
    PubMed
  • No.: 11
  • 文献情報:
    Li S et al. Activation of MAPK signaling by CXCR7 leads to enzalutamide resistance in prostate cancer. Cancer Res. 2019 Apr;
    Li S et al
    2019/01/01
  • 備考:
    Species: Human, Applications: Western Blot
  • 参照:
    PubMed
  • No.: 12
  • 文献情報:
    Bug G et al. Rho family small GTPases control migration of hematopoietic progenitor cells into multicellular spheroids of bone marrow stroma cells. J. Leukoc. Biol. 2002 Oct;72(4):837-45
    Bug G et al
    2002/01/01
  • 備考:
    Species: Human, Applications: ICC
  • 参照:
    PubMed
  • No.: 13
  • 文献情報:
    Deiva K et al. CCR5-, DC-SIGN-dependent endocytosis and delayed reverse transcription after human immunodeficiency virus type 1 infection in human astrocytes. AIDS Res. Hum. Retroviruses 2006 Nov;22(11):1152-61
    Deiva K et al
    2006/01/01
  • 備考:
    Species: Human, Applications: Neutralization
  • 参照:
    PubMed
  • No.: 14
  • 文献情報:
    Tavor S et al. CXCR4 regulates migration and development of human acute myelogenous leukemia stem cells in transplanted NOD/SCID mice. Cancer Res. 2004 Apr;64(8):2817-24
    Tavor S et al
    2004/01/01
  • 備考:
    Species: Human, Applications: ICC
  • 参照:
    PubMed
  • No.: 15
  • 文献情報:
    Lisignoli G et al. Hyaluronan-based polymer scaffold modulates the expression of inflammatory and degradative factors in mesenchymal stem cells: Involvement of Cd44 and Cd54. J. Cell. Physiol. 2006 May;207(2):364-73
    Lisignoli G et al
    2006/01/01
  • 備考:
    Species: Human, Applications: ICC
  • 参照:
    PubMed
  • No.: 16
  • 文献情報:
    Honczarenko M et al. CCR5-binding chemokines modulate CXCL12 (SDF-1)-induced responses of progenitor B cells in human bone marrow through heterologous desensitization of the CXCR4 chemokine receptor. Blood 2002 Oct;100(7):2321-9
    Honczarenko M et al
    2002/01/01
  • 備考:
    Species: Human, Applications: Flow Cytometry
  • 参照:
    PubMed
  • No.: 17
  • 文献情報:
    Kobune M et al. Interaction with human stromal cells enhances CXCR4 expression and engraftment of cord blood Lin(-)CD34(-) cells. Exp. Hematol. 2008 Sep;36(9):1121-31
    Kobune M et al
    2008/01/01
  • 備考:
    Species: Human, Applications: Neutralization
  • 参照:
    PubMed
  • No.: 18
  • 文献情報:
    Zhang Y et al. Intracellular localization and constitutive endocytosis of CXCR4 in human CD34+ hematopoietic progenitor cells. Stem Cells 2004;22(6):1015-29
    Zhang Y et al
    2004/01/01
  • 備考:
    Species: Human, Applications: Flow Cytometry
  • 参照:
    PubMed
  • No.: 19
  • 文献情報:
    Dinkel BA et al. GRK2 mediates TCR-induced transactivation of CXCR4 and TCR-CXCR4 complex formation that drives PI3Kγ/PREX1 signaling and T cell cytokine secretion. J. Biol. Chem. 2018 Sep;293(36):14022-14039
    Dinkel BA et al
    2018/01/01
  • 備考:
    Species: Human, Applications: Flow Cytometry
  • 参照:
    PubMed
  • No.: 20
  • 文献情報:
    Shankar V et al. Mesenchymal stromal cell secretome up-regulates 47 kDa CXCR4 expression, and induce invasiveness in neuroblastoma cell lines. PLoS ONE 2015;10(3):e0120069
    Shankar V et al
    2015/01/01
  • 備考:
    Species: Human, Applications: Neutralization
  • 参照:
    PubMed
  • No.: 21
  • 文献情報:
    Schneider P et al. Is high expression of the chemokine receptor CXCR-4 of predictive value for early relapse in childhood acute lymphoblastic leukaemia? Br. J. Haematol. 2002 Nov;119(2):579-80
    Schneider P et al
    2002/01/01
  • 備考:
    Species: Human, Applications: ICC
  • 参照:
    PubMed
  • No.: 22
  • 文献情報:
    Park BH et al. An isoform of C/EBPβ, LIP, regulates expression of the chemokine receptor CXCR4 and modulates breast cancer cell migration. J. Biol. Chem. 2013 Oct;288(40):28656-67
    Park BH et al
    2013/01/01
  • 備考:
    Species: Human, Applications: Neutralization
  • 参照:
    PubMed
  • No.: 23
  • 文献情報:
    Ao M et al. Cross-talk between paracrine-acting cytokine and chemokine pathways promotes malignancy in benign human prostatic epithelium. Cancer Res. 2007 May;67(9):4244-53
    Ao M et al
    2007/01/01
  • 備考:
    Species: Human, Applications: Neutralization
  • 参照:
    PubMed
  • No.: 24
  • 文献情報:
    Mills SC et al. Rac1 plays a role in CXCL12 but not CCL3-induced chemotaxis and Rac1 GEF inhibitor NSC23766 has off target effects on CXCR4. Cell. Signal. 2018 Jan;42:88-96
    Mills SC et al
    2018/01/01
  • 備考:
    Species: Human, Applications: Flow Cytometry
  • 参照:
    PubMed
  • No.: 25
  • 文献情報:
    Lawrence DM et al. Human immunodeficiency virus type 1 infection of human brain-derived progenitor cells. J. Virol. 2004 Jul;78(14):7319-28
    Lawrence DM et al
    2004/01/01
  • 備考:
    Species: Human, Applications: Flow Cytometry
  • 参照:
    PubMed
  • No.: 26
  • 文献情報:
    Huber TB et al. Expression of functional CCR and CXCR chemokine receptors in podocytes. J. Immunol. 2002 Jun;168(12):6244-52
    Huber TB et al
    2002/01/01
  • 備考:
    Species: Human, Applications: IHC-Fr
  • 参照:
    PubMed
  • No.: 27
  • 文献情報:
    Wu WL et al. Δ20 IFITM2 differentially restricts X4 and R5 HIV-1. Proc. Natl. Acad. Sci. U.S.A. 2017 07;114(27):7112-7117
    Wu WL et al
    2017/01/01
  • 備考:
    Species: Human, Applications: Flow Cytometry
  • 参照:
    PubMed
  • No.: 28
  • 文献情報:
    Lin YL et al. Mesenchymal Stem Cells Ameliorate Atherosclerotic Lesions via Restoring Endothelial Function. Stem Cells Transl Med 2015 Jan;4(1):44-55
    Lin YL et al
    2015/01/01
  • 備考:
    Species: Human, Applications: Neutralization
  • 参照:
    PubMed
  • No.: 29
  • 文献情報:
    Han Y et al. CXCR7 maintains osteosarcoma invasion after CXCR4 suppression in bone marrow microenvironment. Tumour Biol. 2017 May;39(5):1010428317701631
    Han Y et al
    2017/01/01
  • 備考:
    Species: Human, Applications: Neutralization
  • 参照:
    PubMed
  • No.: 30
  • 文献情報:
    Lopez-Haber C et al. Heregulin/ErbB3 Signaling Enhances CXCR4-Driven Rac1 Activation and Breast Cancer Cell Motility via Hypoxia-Inducible Factor 1α. Mol. Cell. Biol. 2016 Aug;36(15):2011-26
    Lopez-Haber C et al
    2016/01/01
  • 備考:
    Species: Human, Applications: Neutralization Control
  • 参照:
    PubMed
  • No.: 31
  • 文献情報:
    Wescott MP et al. Signal transmission through the CXC chemokine receptor 4 (CXCR4) transmembrane helices. Proc. Natl. Acad. Sci. U.S.A. 2016 Aug;113(35):9928-33
    Wescott MP et al
    2016/01/01
  • 備考:
    Species: Human, Applications: IHC-Fr
  • 参照:
    PubMed