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在庫・価格 : 2025年06月24日 16時29分 現在

商品名 商品コード メーカー 包装 価格 在庫 リスト
Anti-Gephyrin, Mouse-Mono(mAb7a(GlyR7a))
データシート
147011 SS2シナプティックシステムズ
Synaptic Systems GmbH
100 μg ¥124,000
(未発注)
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在庫・価格 : 2025年06月24日 16時29分 現在

Anti-Gephyrin, Mouse-Mono(mAb7a(GlyR7a))

  • 商品コード:147011
  • メーカー:SS2
  • 包装:100μg
  • 価格: ¥124,000
  • 在庫:無(未発注)
使用文献
No. 文献情報 備考 参照
1 Pribiag H et al. TNF-α downregulates inhibitory neurotransmission through protein phosphatase 1-dependent trafficking of GABA(A) receptors. J. Neurosci. 2013 Oct;33(40):15879-93
Pribiag H et al
2013/01/01
application: ICC, species: rat PubMed
2 Hennekinne L et al. Differential control of thrombospondin over synaptic glycine and AMPA receptors in spinal cord neurons. J. Neurosci. 2013 Jul;33(28):11432-9
Hennekinne L et al
2013/01/01
application: ICC, species: rat PubMed
3 Wang X et al. Postsynaptic FMRP Regulates Synaptogenesis <i>In Vivo</i> in the Developing Cochlear Nucleus. J. Neurosci. 2018 Jul;38(29):6445-6460
Wang X et al
2018/01/01
application: IHC, species: chicken PubMed
4 Tabuchi K et al. A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice. Science 2007 Oct;318(5847):71-6
Tabuchi K et al
2007/01/01
application: WB, species: mouse PubMed
5 Jiang DY et al. GABAergic deficits and schizophrenia-like behaviors in a mouse model carrying patient-derived neuroligin-2 R215H mutation. Mol Brain 2018 06;11(1):31
Jiang DY et al
2018/01/01
application: IHC, species: mouse PubMed
6 Matsuno T et al. Synaptic distribution of individually labeled mitral cells in the external plexiform layer of the mouse olfactory bulb. J. Comp. Neurol. 2017 May;525(7):1633-1648
Matsuno T et al
2017/01/01
application: IHC, species: mouse PubMed
7 Dejanovic B et al. Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies. Neuron 2018 Dec;100(6):1322-1336.e7
Dejanovic B et al
2018/01/01
application: ICC, species: mouse PubMed
8 Skilbeck KJ et al. Long-lasting effects of early-life intervention in mice on adulthood behaviour, GABA<sub>A</sub> receptor subunit expression and synaptic clustering. Pharmacol. Res. 2018 02;128:179-189
Skilbeck KJ et al
2018/01/01
application: IHC, species: mouse PubMed
9 Awasthi A et al. Synaptotagmin-3 drives AMPA receptor endocytosis, depression of synapse strength, and forgetting. Science 2019 Jan;363(6422)
Awasthi A et al
2019/01/01
application: ICC, species: rat PubMed
10 Hildebrandt H et al. Synaptic reorganization in the adult rats ventral cochlear nucleus following its total sensory deafferentation. PLoS ONE 2011;6(8):e23686
Hildebrandt H et al
2011/01/01
PubMed
11 Bleckert A et al. Spatial Relationships between GABAergic and Glutamatergic Synapses on the Dendrites of Distinct Types of Mouse Retinal Ganglion Cells across Development. PLoS ONE 2013;8(7):e69612
Bleckert A et al
2013/01/01
PubMed
12 Li Z et al. Distribution of gephyrin-immunoreactivity in the trigeminal motor nucleus: an immunohistochemical study in rats. Anat Rec (Hoboken) 2012 Apr;295(4):641-51
Li Z et al
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PubMed
13 Polg叩r E et al. Quantitative study of NPY-expressing GABAergic neurons and axons in rat spinal dorsal horn. J. Comp. Neurol. 2011 Apr;519(6):1007-23
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14 Panzanelli P et al. Distinct mechanisms regulate GABAA receptor and gephyrin clustering at perisomatic and axo-axonic synapses on CA1 pyramidal cells. J. Physiol. (Lond.) 2011 Oct;589(Pt 20):4959-80
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2011/01/01
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15 Garcia I et al. Tracing synaptic connectivity onto embryonic stem cell-derived neurons. Stem Cells 2012 Oct;30(10):2140-51
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16 Peden DR et al. Developmental maturation of synaptic and extrasynaptic GABAA receptors in mouse thalamic ventrobasal neurones. J. Physiol. (Lond.) 2008 Feb;586(4):965-87
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17 K旦rber C et al. Effects of distinct collybistin isoforms on the formation of GABAergic synapses in hippocampal neurons. Mol. Cell. Neurosci. 2012 Jul;50(3-4):250-9
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18 Tyagarajan SK et al. Extracellular signal-regulated kinase and glycogen synthase kinase 3&#x3B2; regulate gephyrin postsynaptic aggregation and GABAergic synaptic function in a calpain-dependent mechanism. J. Biol. Chem. 2013 Apr;288(14):9634-47
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19 Hruskova B et al. Differential distribution of glycine receptor subtypes at the rat calyx of Held synapse. J. Neurosci. 2012 Nov;32(47):17012-24
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20 F旦rstera B et al. Irregular RNA splicing curtails postsynaptic gephyrin in the cornu ammonis of patients with epilepsy. Brain 2010 Dec;133(Pt 12):3778-94
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21 Schneider Gasser EM et al. Immunofluorescence in brain sections: simultaneous detection of presynaptic and postsynaptic proteins in identified neurons. Nat Protoc 2006;1(4):1887-97
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22 Grady RM et al. Cerebellar synaptic defects and abnormal motor behavior in mice lacking alpha- and beta-dystrobrevin. J Neurosci 2006 Mar;26(11):2841-51
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23 Aloy EM et al. Synaptic destabilization by neuronal Nogo-A. Brain Cell Biol 2006 Jun;35(2-3):137-56
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24 Maas C et al. Neuronal cotransport of glycine receptor and the scaffold protein gephyrin. J Cell Biol 2006 Jan;172(3):441-51
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25 Graf ER et al. Structure function and splice site analysis of the synaptogenic activity of the neurexin-1 beta LNS domain. J Neurosci 2006 Apr;26(16):4256-65
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26 Kralic JE et al. Compensatory alteration of inhibitory synaptic circuits in cerebellum and thalamus of gamma-aminobutyric acid type A receptor alpha1 subunit knockout mice. J Comp Neurol 2006 Apr;495(4):408-21
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27 Hartman KN et al. Activity-dependent regulation of inhibitory synaptic transmission in hippocampal neurons. Nat Neurosci 2006 May;9(5):642-9
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28 Jacob TC et al. Gephyrin regulates the cell surface dynamics of synaptic GABAA receptors. J Neurosci 2005 Nov;25(45):10469-78
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29 Meier J et al. A gephyrin-related mechanism restraining glycine receptor anchoring at GABAergic synapses. J Neurosci 2004 Feb;24(6):1398-405
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30 Oleskevich S et al. Glycinergic miniature synaptic currents and receptor cluster sizes differ between spinal cord interneurons. J Neurophysiol 1999 Jul;82(1):312-9
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33 Mishra A et al. Genetic evidence for the adhesion protein IgSF9/Dasm1 to regulate inhibitory synapse development independent of its intracellular domain. J. Neurosci. 2014 Mar;34(12):4187-99
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34 Specht CG et al. Quantitative nanoscopy of inhibitory synapses: counting gephyrin molecules and receptor binding sites. Neuron 2013 Jul;79(2):308-21
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PubMed
35 Lorenzo LE et al. Gephyrin clusters are absent from small diameter primary afferent terminals despite the presence of GABA(A) receptors. J. Neurosci. 2014 Jun;34(24):8300-17
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PubMed
36 King AN et al. A unique ion channel clustering domain on the axon initial segment of mammalian neurons. J. Comp. Neurol. 2014 Aug;522(11):2594-608
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37 Petrini EM et al. Synaptic recruitment of gephyrin regulates surface GABAA receptor dynamics for the expression of inhibitory LTP. Nat Commun 2014 Jun;5:3921
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PubMed
38 Wang SH et al. Dlg5 regulates dendritic spine formation and synaptogenesis by controlling subcellular N-cadherin localization. J. Neurosci. 2014 Sep;34(38):12745-61
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PubMed
39 Hausrat TJ et al. Radixin regulates synaptic GABAA receptor density and is essential for reversal learning and short-term memory. Nat Commun 2015 Apr;6:6872
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40 Laht P et al. Plexin-B3 suppresses excitatory and promotes inhibitory synapse formation in rat hippocampal neurons. Exp. Cell Res. 2015 Jul;335(2):269-78
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41 Varea O et al. Synaptic abnormalities and cytoplasmic glutamate receptor aggregates in contactin associated protein-like 2/Caspr2 knockout neurons. Proc Natl Acad Sci U S A 2015 May;112(19):6176-81
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42 He Q et al. Interneuron- and GABA(A) receptor-specific inhibitory synaptic plasticity in cerebellar Purkinje cells. Nat Commun 2015 Jul;6:7364
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43 Brigidi GS et al. Activity-regulated trafficking of the palmitoyl-acyl transferase DHHC5. Nat Commun 2015;6:8200
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44 Bartel DL et al. Dendrodendritic synapses in the mouse olfactory bulb external plexiform layer. J Comp Neurol 2015 Jun;523(8):1145-61
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45 Rathgeber L et al. GSK3 and KIF5 regulate activity-dependent sorting of gephyrin between axons and dendrites. Eur. J. Cell Biol. ;94(3-4):173-8
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46 Papadopoulos T et al. Lipid binding defects and perturbed synaptogenic activity of a Collybistin R290H mutant that causes epilepsy and intellectual disability. J. Biol. Chem. 2015 Mar;290(13):8256-70
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47 Vullhorst D et al. A negative feedback loop controls NMDA receptor function in cortical interneurons via neuregulin 2/ErbB4 signalling. Nat Commun 2015 Jun;6:7222
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48 Deprez F et al. Postsynaptic gephyrin clustering controls the development of adult-born granule cells in the olfactory bulb. J. Comp. Neurol. 2015 Sep;523(13):1998-2016
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49 Toossi H et al. Somatostatin varicosities contain the vesicular GABA transporter and contact orexin neurons in the hypothalamus. Eur J Neurosci 2012 Nov;36(10):3388-95
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50 Fuchs T et al. Disinhibition of somatostatin-positive GABAergic interneurons results in an anxiolytic and antidepressant-like brain state. Mol. Psychiatry 2017 06;22(6):920-930
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51 Chang JB et al. Iterative expansion microscopy. Nat. Methods 2017 Jun;14(6):593-599
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52 Panzanelli P et al. Differential role of GABA<sub>A</sub> receptors and neuroligin 2 for perisomatic GABAergic synapse formation in the hippocampus. Brain Struct Funct 2017 Dec;222(9):4149-4161
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53 Laperchia C et al. The excitatory/inhibitory input to orexin/hypocretin neuron soma undergoes day/night reorganization. Brain Struct Funct 2017 Nov;222(8):3847-3859
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55 Pennacchietti F et al. Nanoscale Molecular Reorganization of the Inhibitory Postsynaptic Density Is a Determinant of GABAergic Synaptic Potentiation. J. Neurosci. 2017 02;37(7):1747-1756
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56 Brady ML et al. Depolarizing, inhibitory GABA type A receptor activity regulates GABAergic synapse plasticity via ERK and BDNF signaling. Neuropharmacology 2018 Jan;128:324-339
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57 Feng G et al. Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity. Science 1998 Nov;282(5392):1321-4
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58 Yazulla S et al. Neurochemical anatomy of the zebrafish retina as determined by immunocytochemistry. J Neurocytol 2001 Jul;30(7):551-92
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59 Patrizio A et al. Alpha subunit-dependent glycine receptor clustering and regulation of synaptic receptor numbers. Sci Rep 2017 09;7(1):10899
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60 Kang Y et al. Induction of GABAergic postsynaptic differentiation by alpha-neurexins. J. Biol. Chem. 2008 Jan;283(4):2323-34
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61 Belichenko PV et al. Excitatory-inhibitory relationship in the fascia dentata in the Ts65Dn mouse model of Down syndrome. J Comp Neurol 2009 Feb;512(4):453-66
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62 Hughes EG et al. Astrocyte secreted proteins selectively increase hippocampal GABAergic axon length, branching, and synaptogenesis. Mol Cell Neurosci 2010 Jan;43(1):136-45
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63 Gao Y et al. Enrichment of GABAA Receptor &#x3B1;-Subunits on the Axonal Initial Segment Shows Regional Differences. Front Cell Neurosci 2016;10:39
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64 Dufour A et al. Mixed GABA-glycine synapses delineate a specific topography in the nucleus tractus solitarii of adult rat. J. Physiol. (Lond.) 2010 Apr;588(Pt 7):1097-115
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65 Tretter V et al. Molecular basis of the &#x3B3;-aminobutyric acid A receptor &#x3B1;3 subunit interaction with the clustering protein gephyrin. J Biol Chem 2011 Oct;286(43):37702-11
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66 Del Pino I et al. Proteomic analysis of glycine receptor &#x3B2; subunit (GlyR&#x3B2;)-interacting proteins: evidence for syndapin I regulating synaptic glycine receptors. J Biol Chem 2014 Apr;289(16):11396-11409
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67 Dzyubenko E et al. The antipsychotic drugs olanzapine and haloperidol modify network connectivity and spontaneous activity of neural networks in vitro. Sci Rep 2017 Sep;7(1):11609
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68 Fang C et al. Prions activate a p38 MAPK synaptotoxic signaling pathway. PLoS Pathog 2018 09;14(9):e1007283
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69 Wamsley B et al. Rbfox1 Mediates Cell-type-Specific Splicing in Cortical Interneurons. Neuron 2018 11;100(4):846-859.e7
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70 Dhar M et al. Developmental pattern and structural factors of dendritic survival in cerebellar granule cells in vivo. Sci Rep 2018 12;8(1):17561
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71 Ge Y et al. Clptm1 Limits Forward Trafficking of GABA<sub>A</sub> Receptors to Scale Inhibitory Synaptic Strength. Neuron 2018 02;97(3):596-610.e8
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72 Hollnagel JO et al. Early alterations in hippocampal perisomatic GABAergic synapses and network oscillations in a mouse model of Alzheimer&#39;s disease amyloidosis. PLoS One 2019;14(1):e0209228
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73 Yamasaki T et al. GARLH Family Proteins Stabilize GABA<sub>A</sub> Receptors at Synapses. Neuron 2017 Mar;93(5):1138-1152.e6
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74 Shao Z et al. Dysregulated protocadherin-pathway activity as an intrinsic defect in induced pluripotent stem cell-derived cortical interneurons from subjects with schizophrenia. Nat Neurosci 2019 02;22(2):229-242
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75 Favuzzi E et al. Activity-Dependent Gating of Parvalbumin Interneuron Function by the Perineuronal Net Protein Brevican. Neuron 2017 Aug;95(3):639-655.e10
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76 Davenport EC et al. Autism and Schizophrenia-Associated CYFIP1 Regulates the Balance of Synaptic Excitation and Inhibition. Cell Rep 2019 02;26(8):2037-2051.e6
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77 Tai Y et al. Axo-axonic Innervation of Neocortical Pyramidal Neurons by GABAergic Chandelier Cells Requires AnkyrinG-Associated L1CAM. Neuron 2019 04;102(2):358-372.e9
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78 Crosby KC et al. Nanoscale Subsynaptic Domains Underlie the Organization of the Inhibitory Synapse. Cell Rep 2019 03;26(12):3284-3297.e3
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79 Kroon T et al. Early postnatal development of pyramidal neurons across layers of the mouse medial prefrontal cortex. Sci Rep 2019 03;9(1):5037
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80 Hu HY et al. Endocannabinoid Signaling Mediates Local Dendritic Coordination between Excitatory and Inhibitory Synapses. Cell Rep 2019 04;27(3):666-675.e5
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81 Lin TW et al. Regulation of Synapse Development by <i>Vgat</i> Deletion from ErbB4-Positive Interneurons. J Neurosci 2018 03;38(10):2533-2550
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82 Dondzillo A et al. Recurrent Inhibition to the Medial Nucleus of the Trapezoid Body in the Mongolian Gerbil (Meriones Unguiculatus). PLoS One 2016;11(8):e0160241
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83 Kwon Y et al. &#x3B2;Pix heterozygous mice have defects in neuronal morphology and social interaction. Biochem Biophys Res Commun 2019 09;516(4):1204-1210
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84 Acton D et al. Spinal Neuropeptide Y1 Receptor-Expressing Neurons Form an Essential Excitatory Pathway for Mechanical Itch. Cell Rep 2019 07;28(3):625-639.e6
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85 Shah BS et al. Regulation of dendrite morphology and excitatory synapse formation by zDHHC15. J. Cell. Sci. 2019 Jul;132(13)
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86 Hu G et al. HIV-1 Tat-Induced Astrocytic Extracellular Vesicle miR-7 Impairs Synaptic Architecture. J Neuroimmune Pharmacol 2020 09;15(3):538-553
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PubMed
87 Mukherjee A et al. Long-Lasting Rescue of Network and Cognitive Dysfunction in a Genetic Schizophrenia Model. Cell 2019 09;178(6):1387-1402.e14
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88 Gao X et al. Disturbed Prefrontal Cortex Activity in the Absence of Schizophrenia-Like Behavioral Dysfunction in <i>Arc/Arg3.1</i> Deficient Mice. J Neurosci 2019 10;39(41):8149-8163
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PubMed
89 Gottschling C et al. Elimination of the four extracellular matrix molecules tenascin-C, tenascin-R, brevican and neurocan alters the ratio of excitatory and inhibitory synapses. Sci Rep 2019 09;9(1):13939
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90 Esposito A et al. Biallelic DMXL2 mutations impair autophagy and cause Ohtahara syndrome with progressive course. Brain 2019 12;142(12):3876-3891
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91 Fossati M et al. Trans-Synaptic Signaling through the Glutamate Receptor Delta-1 Mediates Inhibitory Synapse Formation in Cortical Pyramidal Neurons. Neuron 2019 12;104(6):1081-1094.e7
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92 Shimell JJ et al. The X-Linked Intellectual Disability Gene Zdhhc9 Is Essential for Dendrite Outgrowth and Inhibitory Synapse Formation. Cell Rep 2019 11;29(8):2422-2437.e8
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93 Halff EF et al. SNX27-Mediated Recycling of Neuroligin-2 Regulates Inhibitory Signaling. Cell Rep 2019 11;29(9):2599-2607.e6
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94 Kilisch M et al. A GTPase-induced switch in phospholipid affinity of collybistin contributes to synaptic gephyrin clustering. J Cell Sci 2020 01;133(2)
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96 Lorenzo LE et al. Enhancing neuronal chloride extrusion rescues &#x3B1;2/&#x3B1;3 GABA<sub>A</sub>-mediated analgesia in neuropathic pain. Nat Commun 2020 02;11(1):869
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97 Bannatyne BA et al. Neurotransmitters and Motoneuron Contacts of Multifunctional and Behaviorally Specialized Turtle Spinal Cord Interneurons. J Neurosci 2020 03;40(13):2680-2694
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98 De Fusco A et al. Acute knockdown of Depdc5 leads to synaptic defects in mTOR-related epileptogenesis. Neurobiol Dis 2020 06;139:104822
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99 Frias CP et al. Semaphorin4D Induces Inhibitory Synapse Formation by Rapid Stabilization of Presynaptic Boutons via MET Coactivation. J Neurosci 2019 05;39(22):4221-4237
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PubMed
  • No.: 1
  • 文献情報:
    Pribiag H et al. TNF-&#x3B1; downregulates inhibitory neurotransmission through protein phosphatase 1-dependent trafficking of GABA(A) receptors. J. Neurosci. 2013 Oct;33(40):15879-93
    Pribiag H et al
    2013/01/01
  • 備考:
    application: ICC, species: rat
  • 参照:
    PubMed
  • No.: 2
  • 文献情報:
    Hennekinne L et al. Differential control of thrombospondin over synaptic glycine and AMPA receptors in spinal cord neurons. J. Neurosci. 2013 Jul;33(28):11432-9
    Hennekinne L et al
    2013/01/01
  • 備考:
    application: ICC, species: rat
  • 参照:
    PubMed
  • No.: 3
  • 文献情報:
    Wang X et al. Postsynaptic FMRP Regulates Synaptogenesis <i>In Vivo</i> in the Developing Cochlear Nucleus. J. Neurosci. 2018 Jul;38(29):6445-6460
    Wang X et al
    2018/01/01
  • 備考:
    application: IHC, species: chicken
  • 参照:
    PubMed
  • No.: 4
  • 文献情報:
    Tabuchi K et al. A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice. Science 2007 Oct;318(5847):71-6
    Tabuchi K et al
    2007/01/01
  • 備考:
    application: WB, species: mouse
  • 参照:
    PubMed
  • No.: 5
  • 文献情報:
    Jiang DY et al. GABAergic deficits and schizophrenia-like behaviors in a mouse model carrying patient-derived neuroligin-2 R215H mutation. Mol Brain 2018 06;11(1):31
    Jiang DY et al
    2018/01/01
  • 備考:
    application: IHC, species: mouse
  • 参照:
    PubMed
  • No.: 6
  • 文献情報:
    Matsuno T et al. Synaptic distribution of individually labeled mitral cells in the external plexiform layer of the mouse olfactory bulb. J. Comp. Neurol. 2017 May;525(7):1633-1648
    Matsuno T et al
    2017/01/01
  • 備考:
    application: IHC, species: mouse
  • 参照:
    PubMed
  • No.: 7
  • 文献情報:
    Dejanovic B et al. Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies. Neuron 2018 Dec;100(6):1322-1336.e7
    Dejanovic B et al
    2018/01/01
  • 備考:
    application: ICC, species: mouse
  • 参照:
    PubMed
  • No.: 8
  • 文献情報:
    Skilbeck KJ et al. Long-lasting effects of early-life intervention in mice on adulthood behaviour, GABA<sub>A</sub> receptor subunit expression and synaptic clustering. Pharmacol. Res. 2018 02;128:179-189
    Skilbeck KJ et al
    2018/01/01
  • 備考:
    application: IHC, species: mouse
  • 参照:
    PubMed
  • No.: 9
  • 文献情報:
    Awasthi A et al. Synaptotagmin-3 drives AMPA receptor endocytosis, depression of synapse strength, and forgetting. Science 2019 Jan;363(6422)
    Awasthi A et al
    2019/01/01
  • 備考:
    application: ICC, species: rat
  • 参照:
    PubMed
  • No.: 10
  • 文献情報:
    Hildebrandt H et al. Synaptic reorganization in the adult rats ventral cochlear nucleus following its total sensory deafferentation. PLoS ONE 2011;6(8):e23686
    Hildebrandt H et al
    2011/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 11
  • 文献情報:
    Bleckert A et al. Spatial Relationships between GABAergic and Glutamatergic Synapses on the Dendrites of Distinct Types of Mouse Retinal Ganglion Cells across Development. PLoS ONE 2013;8(7):e69612
    Bleckert A et al
    2013/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 12
  • 文献情報:
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