IGF-I/IGF-1, Human, Recombinant, Carrier-free

データシート

• 商品コード：291-G1-200
• メーカー：RSD
• 包装：200μg
• 価格： ¥54,000
• 在庫：1個

マイリストに追加 マイリストに追加済

• No.： 1
• 文献情報：
  Deleu S et al. Immediate early gene expression in dog thyrocytes in response to growth, proliferation, and differentiation stimuli. J. Cell. Physiol. 1999 Nov;181(2):342-54
  Deleu S et al
  1999/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 2
• 文献情報：
  Loeser RF et al. Reduction in the chondrocyte response to insulin-like growth factor 1 in aging and osteoarthritis: studies in a non-human primate model of naturally occurring disease. Arthritis Rheum. 2000 Sep;43(9):2110-20
  Loeser RF et al
  2000/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 3
• 文献情報：
  Loukinova E et al. Platelet-derived growth factor (PDGF)-induced tyrosine phosphorylation of the low density lipoprotein receptor-related protein (LRP). Evidence for integrated co-receptor function betwenn LRP and the PDGF. J. Biol. Chem. 2002 May;277(18)
  Loukinova E et al
  2002/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 4
• 文献情報：
  Shi Y et al. Signal pathways involved in activation of p70S6K and phosphorylation of 4E-BP1 following exposure of multiple myeloma tumor cells to interleukin-6. J. Biol. Chem. 2002 May;277(18):15712-20
  Shi Y et al
  2002/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 5
• 文献情報：
  Armstrong LC et al. Thrombospondin 2 inhibits microvascular endothelial cell proliferation by a caspase-independent mechanism. Mol. Biol. Cell 2002 Jun;13(6):1893-905
  Armstrong LC et al
  2002/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 6
• 文献情報：
  Derevjanik NL et al. Quantitative assessment of the integrity of the blood-retinal barrier in mice. Invest. Ophthalmol. Vis. Sci. 2002 Jul;43(7):2462-7
  Derevjanik NL et al
  2002/01/01
  
• 備考：
  Application: In Vivo
• 参照：
  

• No.： 7
• 文献情報：
  Mitsiades CS et al. Activation of NF-kappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications. Oncogene 2002 Aug;21(37):5673-83
  Mitsiades CS et al
  2002/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 8
• 文献情報：
  Loeser RF et al. Detection of nitrotyrosine in aging and osteoarthritic cartilage: Correlation of oxidative damage with the presence of interleukin-1beta and with chondrocyte resistance to insulin-like growth factor 1. Arthritis Rheum. 2002 Sep;46(9):2349
  Loeser RF et al
  2002/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 9
• 文献情報：
  Nakayama N et al. Macroscopic cartilage formation with embryonic stem-cell-derived mesodermal progenitor cells. J. Cell. Sci. 2003 May;116(Pt 10):2015-28
  Nakayama N et al
  2003/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 10
• 文献情報：
  Levenberg S et al. Differentiation of human embryonic stem cells on three-dimensional polymer scaffolds. Proc. Natl. Acad. Sci. U.S.A. 2003 Oct;100(22):12741-6
  Levenberg S et al
  2003/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 11
• 文献情報：
  Burtrum D et al. A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo. Cancer Res. 2003 Dec;63(24):8912-21
  Burtrum D et al
  2003/01/01
  
• 備考：
  Application: Biacore binding study,Binding Assay,Bioassay, Sample Type: Whole Cells,recombinant IGF-1R
• 参照：
  

• No.： 12
• 文献情報：
  Hsieh J et al. IGF-I instructs multipotent adult neural progenitor cells to become oligodendrocytes. J. Cell Biol. 2004 Jan;164(1):111-22
  Hsieh J et al
  2004/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 13
• 文献情報：
  Oropeza A et al. Improvement of the developmental capacity of oocytes from prepubertal cattle by intraovarian insulin-like growth factor-I application. Biol. Reprod. 2004 Jun;70(6):1634-43
  Oropeza A et al
  2004/01/01
  
• 備考：
  Application: In Vivo
• 参照：
  

• No.： 14
• 文献情報：
  Studer RK et al. Chondrocyte response to growth factors is modulated by p38 mitogen-activated protein kinase inhibition. Arthritis Res. Ther. 2004;6(1):R56-R64
  Studer RK et al
  2004/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 15
• 文献情報：
  Raiche AT et al. Cell responses to BMP-2 and IGF-I released with different time-dependent profiles. J Biomed Mater Res A 2004 May;69(2):342-50
  Raiche AT et al
  2004/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 16
• 文献情報：
  Wildemann B et al. Local delivery of growth factors from coated titanium plates increases osteotomy healing in rats. Bone 2004 May;34(5):862-8
  Wildemann B et al
  2004/01/01
  
• 備考：
  Application: In Vivo, Sample Type: Bone Implant
• 参照：
  

• No.： 17
• 文献情報：
  Parikh AA et al. Neuropilin-1 in human colon cancer: expression, regulation, and role in induction of angiogenesis. Am. J. Pathol. 2004 Jun;164(6):2139-51
  Parikh AA et al
  2004/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 18
• 文献情報：
  Wildemann B et al. Quantification, localization, and expression of IGF-I and TGF-beta1 during growth factor-stimulated fracture healing. Calcif. Tissue Int. 2004 Apr;74(4):388-97
  Wildemann B et al
  2004/01/01
  
• 備考：
  Application: In Vivo
• 参照：
  

• No.： 19
• 文献情報：
  Liu Z et al. Chemotaxis and chemokinesis of malignant mesothelioma cells to multiple growth factors. Anticancer Res. ;24(3a):1625-30
  Liu Z et al
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 20
• 文献情報：
  Gahr SA et al. The effects of in ovo rhIGF-I administration on expression of the growth hormone secretagogue receptor (GHSR) during chicken embryonic development. Growth Dev Aging 2004;68(1):3-10
  Gahr SA et al
  2004/01/01
  
• 備考：
  Application: In Vivo
• 参照：
  

• No.： 21
• 文献情報：
  Escartin C et al. Insulin growth factor-1 protects against excitotoxicity in the rat striatum. Neuroreport 2004 Oct;15(14):2251-4
  Escartin C et al
  2004/01/01
  
• 備考：
  Application: In Vivo
• 参照：
  

• No.： 22
• 文献情報：
  Bauer TW et al. Insulinlike growth factor-I-mediated migration and invasion of human colon carcinoma cells requires activation of c-Met and urokinase plasminogen activator receptor. Ann. Surg. 2005 May;241(5):748-56; discussion 756-8
  Bauer TW et al
  2005/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 23
• 文献情報：
  Shiraki N et al. TGF-beta signaling potentiates differentiation of embryonic stem cells to Pdx-1 expressing endodermal cells. Genes Cells 2005 Jun;10(6):503-16
  Shiraki N et al
  2005/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 24
• 文献情報：
  Hanley MB et al. Growth hormone-induced stimulation of multilineage human hematopoiesis. Stem Cells 2005 Sep;23(8):1170-9
  Hanley MB et al
  2005/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 25
• 文献情報：
  Glod J et al. Monocytes form a vascular barrier and participate in vessel repair after brain injury. Blood 2006 Feb;107(3):940-6
  Glod J et al
  2006/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 26
• 文献情報：
  McDevitt TC et al. Proliferation of cardiomyocytes derived from human embryonic stem cells is mediated via the IGF/PI 3-kinase/Akt signaling pathway. J. Mol. Cell. Cardiol. 2005 Dec;39(6):865-73
  McDevitt TC et al
  2005/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 27
• 文献情報：
  Sailer MH et al. BMP2 and FGF2 cooperate to induce neural-crest-like fates from fetal and adult CNS stem cells. J. Cell. Sci. 2005 Dec;118(Pt 24):5849-60
  Sailer MH et al
  2005/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 28
• 文献情報：
  Larsen PH et al. Myelin formation during development of the CNS is delayed in matrix metalloproteinase-9 and -12 null mice. J. Neurosci. 2006 Feb;26(8):2207-14
  Larsen PH et al
  2006/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 29
• 文献情報：
  Moreno MJ et al. Insulin-like growth factor binding protein-4 (IGFBP-4) is a novel anti-angiogenic and anti-tumorigenic mediator secreted by dibutyryl cyclic AMP (dB-cAMP)-differentiated glioblastoma cells. Glia 2006 Jun;53(8):845-57
  Moreno MJ et al
  2006/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 30
• 文献情報：
  Kawada M et al. Insulin-like growth factor I secreted from prostate stromal cells mediates tumor-stromal cell interactions of prostate cancer. Cancer Res. 2006 Apr;66(8):4419-25
  Kawada M et al
  2006/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 31
• 文献情報：
  Spicer LJ et al. Growth differentiation factor-9 has divergent effects on proliferation and steroidogenesis of bovine granulosa cells. J. Endocrinol. 2006 May;189(2):329-39
  Spicer LJ et al
  2006/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 32
• 文献情報：
  Li Y et al. Transforming growth factor-alpha: a major human serum factor that promotes human keratinocyte migration. J. Invest. Dermatol. 2006 Sep;126(9):2096-105
  Li Y et al
  2006/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 33
• 文献情報：
  Anderson BC et al. Increased extraocular muscle strength with direct injection of insulin-like growth factor-I. Invest. Ophthalmol. Vis. Sci. 2006 Jun;47(6):2461-7
  Anderson BC et al
  2006/01/01
  
• 備考：
  Application: In Vivo
• 参照：
  

• No.： 34
• 文献情報：
  Liu Y et al. A novel chemical-defined medium with bFGF and N2B27 supplements supports undifferentiated growth in human embryonic stem cells. Biochem. Biophys. Res. Commun. 2006 Jul;346(1):131-9
  Liu Y et al
  2006/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 35
• 文献情報：
  Park BJ et al. AIMP3 haploinsufficiency disrupts oncogene-induced p53 activation and genomic stability. Cancer Res. 2006 Jul;66(14):6913-8
  Park BJ et al
  2006/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 36
• 文献情報：
  Wang Z et al. Growth-inhibitory effects of human anti-insulin-like growth factor-I receptor antibody (A12) in an orthotopic nude mouse model of anaplastic thyroid carcinoma. Clin. Cancer Res. 2006 Aug;12(15):4755-65
  Wang Z et al
  2006/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 37
• 文献情報：
  Chetty A et al. Insulin-like Growth Factor-I signaling mechanisms, type I collagen and alpha smooth muscle actin in human fetal lung fibroblasts. Pediatr. Res. 2006 Oct;60(4):389-94
  Chetty A et al
  2006/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 38
• 文献情報：
  Nam EJ et al. Up-regulated transforming growth factor beta-inducible gene h3 in rheumatoid arthritis mediates adhesion and migration of synoviocytes through alpha v beta3 integrin: Regulation by cytokines. Arthritis Rheum. 2006 Sep;54(9):2734-44
  Nam EJ et al
  2006/01/01
  
• 備考：
  Application: Media Supplement, Sample Type: Whole Cells
• 参照：
  

• No.： 39
• 文献情報：
  Hideshima T et al. MLN120B, a novel IkappaB kinase beta inhibitor, blocks multiple myeloma cell growth in vitro and in vivo. Clin. Cancer Res. 2006 Oct;12(19):5887-94
  Hideshima T et al
  2006/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 40
• 文献情報：
  Bartunek J et al. Pretreatment of adult bone marrow mesenchymal stem cells with cardiomyogenic growth factors and repair of the chronically infarcted myocardium. Am. J. Physiol. Heart Circ. Physiol. 2007 Feb;292(2):H1095-104
  Bartunek J et al
  2007/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 41
• 文献情報：
  Sheen-Chen SM et al. The effect of insulin-like growth factor-I on hepatocyte apoptosis after bile duct ligation in rat. Dig. Dis. Sci. 2006 Dec;51(12):2220-4
  Sheen-Chen SM et al
  2006/01/01
  
• 備考：
  Application: In Vivo
• 参照：
  

• No.： 42
• 文献情報：
  Spicer LJ et al. Insulin-like growth factor (IGF) 2 stimulates steroidogenesis and mitosis of bovine granulosa cells through the IGF1 receptor: role of follicle-stimulating hormone and IGF2 receptor. Biol. Reprod. 2007 Jul;77(1):18-27
  Spicer LJ et al
  2007/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 43
• 文献情報：
  Wanderling S et al. GRP94 is essential for mesoderm induction and muscle development because it regulates insulin-like growth factor secretion. Mol. Biol. Cell 2007 Oct;18(10):3764-75
  Wanderling S et al
  2007/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 44
• 文献情報：
  Escartin C et al. IGF-1 exacerbates the neurotoxicity of the mitochondrial inhibitor 3NP in rats. Neurosci. Lett. 2007 Oct;425(3):167-72
  Escartin C et al
  2007/01/01
  
• 備考：
  Application: In Vivo, Sample Type: In Vivo
• 参照：
  

• No.： 45
• 文献情報：
  Li JC et al. RAV12 accelerates the desensitization of Akt/PKB pathway of insulin-like growth factor I receptor signaling in COLO205. Cancer Res. 2007 Sep;67(18):8856-64
  Li JC et al
  2007/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 46
• 文献情報：
  Zlei M et al. Characterization of in vitro growth of multiple myeloma cells. Exp. Hematol. 2007 Oct;35(10):1550-61
  Zlei M et al
  2007/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 47
• 文献情報：
  Fuller K et al. Cathepsin K inhibitors prevent matrix-derived growth factor degradation by human osteoclasts. Bone 2008 Jan;42(1):200-11
  Fuller K et al
  2008/01/01
  
• 備考：
  Application: Enzyme Assay, Sample Type: Buffer
• 参照：
  

• No.： 48
• 文献情報：
  Southwood M et al. Regulation of bone morphogenetic protein signalling in human pulmonary vascular development. J. Pathol. 2008 Jan;214(1):85-95
  Southwood M et al
  2008/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 49
• 文献情報：
  Gonzalez RM et al. Development and validation of sandwich ELISA microarrays with minimal assay interference. J. Proteome Res. 2008 Jun;7(6):2406-14
  Gonzalez RM et al
  2008/01/01
  
• 備考：
  Application: ELISA Standard, Sample Type: N/A
• 参照：
  

• No.： 50
• 文献情報：
  Koga T et al. IGFBPs contribute to survival of pancreatic cancer cells under severely hypoxic conditions. Cancer Lett. 2008 Sep;268(1):82-8
  Koga T et al
  2008/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 51
• 文献情報：
  Desbordes SC et al. High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells. Cell Stem Cell 2008 Jun;2(6):602-12
  Desbordes SC et al
  2008/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 52
• 文献情報：
  Piao W et al. Insulin-like growth factor-I receptor blockade by a specific tyrosine kinase inhibitor for human gastrointestinal carcinomas. Mol. Cancer Ther. 2008 Jun;7(6):1483-93
  Piao W et al
  2008/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 53
• 文献情報：
  Banziger-Tobler NE et al. Growth hormone promotes lymphangiogenesis. Am. J. Pathol. 2008 Aug;173(2):586-97
  Banziger-Tobler NE et al
  2008/01/01
  
• 備考：
  Application: Western Blot, Sample Type: N/A
• 参照：
  

• No.： 54
• 文献情報：
  Adachi Y et al. Insulin-like growth factor-I receptor blockade reduces the invasiveness of gastrointestinal cancers via blocking production of matrilysin. Carcinogenesis 2009 Aug;30(8):1305-13
  Adachi Y et al
  2009/01/01
  
• 備考：
  Application: In Vivo, Sample Type: In Vivo
• 参照：
  

• No.： 55
• 文献情報：
  Ryan AJ et al. Expression of a protease-resistant insulin-like growth factor-binding protein-4 inhibits tumour growth in a murine model of breast cancer. Br. J. Cancer 2009 Jul;101(2):278-86
  Ryan AJ et al
  2009/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 56
• 文献情報：
  Maehr R et al. Generation of pluripotent stem cells from patients with type 1 diabetes. Proc. Natl. Acad. Sci. U.S.A. 2009 Sep;106(37):15768-73
  Maehr R et al
  2009/01/01
  
• 備考：
  Application: Media Supplement, Sample Type: Whole Cells
• 参照：
  

• No.： 57
• 文献情報：
  Makinoshima H et al. Pancreatic cancer cells activate CCL5 expression in mesenchymal stromal cells through the insulin-like growth factor-I pathway. FEBS Lett. 2009 Nov;583(22):3697-703
  Makinoshima H et al
  2009/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 58
• 文献情報：
  Fischer AJ et al. A novel type of glial cell in the retina is stimulated by insulin-like growth factor 1 and may exacerbate damage to neurons and Mテδシller glia. Glia 2010 Apr;58(6):633-49
  Fischer AJ et al
  2010/01/01
  
• 備考：
  Sample Type: In Vivo
• 参照：
  

• No.： 59
• 文献情報：
  Roccaro AM et al. Selective inhibition of chymotrypsin-like activity of the immunoproteasome and constitutive proteasome in Waldenstrom macroglobulinemia. Blood 2010 May;115(20):4051-60
  Roccaro AM et al
  2010/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 60
• 文献情報：
  Meuillet EJ et al. Molecular pharmacology and antitumor activity of PHT-427, a novel Akt/phosphatidylinositide-dependent protein kinase 1 pleckstrin homology domain inhibitor. Mol. Cancer Ther. 2010 Mar;9(3):706-17
  Meuillet EJ et al
  2010/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 61
• 文献情報：
  Nishino J et al. Lgi4 promotes the proliferation and differentiation of glial lineage cells throughout the developing peripheral nervous system. J. Neurosci. 2010 Nov;30(45):15228-40
  Nishino J et al
  2010/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 62
• 文献情報：
  Hemingway F et al. RANKL-independent human osteoclast formation with APRIL, BAFF, NGF, IGF I and IGF II. Bone 2011 Apr;48(4):938-44
  Hemingway F et al
  2011/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 63
• 文献情報：
  Romero D et al. Endoglin regulates cancer-stromal cell interactions in prostate tumors. Cancer Res. 2011 May;71(10):3482-93
  Romero D et al
  2011/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 64
• 文献情報：
  Asumda FZ et al. Age-related changes in rat bone-marrow mesenchymal stem cell plasticity. BMC Cell Biol. 2011;12:44
  Asumda FZ et al
  2011/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 65
• 文献情報：
  Iozzo RV et al. Decorin antagonizes IGF receptor I (IGF-IR) function by interfering with IGF-IR activity and attenuating downstream signaling. J. Biol. Chem. 2011 Oct;286(40):34712-21
  Iozzo RV et al
  2011/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 66
• 文献情報：
  Zelinka CP et al. The reactivity, distribution and abundance of Non-astrocytic Inner Retinal Glial (NIRG) cells are regulated by microglia, acute damage, and IGF1. PLoS ONE 2012;7(9):e44477
  Zelinka CP et al
  2012/01/01
  
• 備考：
  Application: In Vivo, Sample Type: In Vivo
• 参照：
  

• No.： 67
• 文献情報：
  Aad PY et al. The hedgehog system in ovarian follicles of cattle selected for twin ovulations and births: evidence of a link between the IGF and hedgehog systems. Biol. Reprod. 2012 Oct;87(4):79
  Aad PY et al
  2012/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 68
• 文献情報：
  Laranjeira AB et al. IGFBP7 participates in the reciprocal interaction between acute lymphoblastic leukemia and BM stromal cells and in leukemia resistance to asparaginase. Leukemia 2012 May;26(5):1001-11
  Laranjeira AB et al
  2012/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 69
• 文献情報：
  Di Maggio N et al. Fibroblast growth factor-2 maintains a niche-dependent population of self-renewing highly potent non-adherent mesenchymal progenitors through FGFR2c. Stem Cells 2012 Jul;30(7):1455-64
  Di Maggio N et al
  2012/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 70
• 文献情報：
  Prabakar KR et al. Generation of glucose-responsive, insulin-producing cells from human umbilical cord blood-derived mesenchymal stem cells. Cell Transplant 2012;21(6):1321-39
  Prabakar KR et al
  2012/01/01
  
• 備考：
  Application: cell culture, Sample Type: whole cells
• 参照：
  

• No.： 71
• 文献情報：
  Thatava T et al. Intrapatient variations in type 1 diabetes-specific iPS cell differentiation into insulin-producing cells. Mol. Ther. 2013 Jan;21(1):228-39
  Thatava T et al
  2013/01/01
  
• 備考：
  Application: Bioassay, Sample Type: whole cells
• 参照：
  

• No.： 72
• 文献情報：
  Logan JG et al. Selective tyrosine kinase inhibition of insulin-like growth factor-1 receptor inhibits human and mouse breast cancer-induced bone cell activity, bone remodeling, and osteolysis. J. Bone Miner. Res. 2013 May;28(5):1229-42
  Logan JG et al
  2013/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 73
• 文献情報：
  Tucker BA et al. Use of a synthetic xeno-free culture substrate for induced pluripotent stem cell induction and retinal differentiation. Stem Cells Transl Med 2013 Jan;2(1):16-24
  Tucker BA et al
  2013/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 74
• 文献情報：
  Wolf A et al. Insulin signaling via Akt2 switches plakophilin 1 function from stabilizing cell adhesion to promoting cell proliferation. J. Cell. Sci. 2013 Apr;126(Pt 8):1832-44
  Wolf A et al
  2013/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 75
• 文献情報：
  Cardillo TM et al. Targeting both IGF-1R and mTOR synergistically inhibits growth of renal cell carcinoma in vitro. BMC Cancer 2013;13:170
  Cardillo TM et al
  2013/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 76
• 文献情報：
  Buchholz DE et al. Rapid and efficient directed differentiation of human pluripotent stem cells into retinal pigmented epithelium. Stem Cells Transl Med 2013 May;2(5):384-93
  Buchholz DE et al
  2013/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 77
• 文献情報：
  Liu Y et al. Medial ganglionic eminence-like cells derived from human embryonic stem cells correct learning and memory deficits. Nat. Biotechnol. 2013 May;31(5):440-7
  Liu Y et al
  2013/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 78
• 文献情報：
  Tucker BA et al. Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa. Elife 2013;2:e00824
  Tucker BA et al
  2013/01/01
  
• 備考：
  Application: differentiation, Sample Type: Whole Cells
• 参照：
  

• No.： 79
• 文献情報：
  Hung CF et al. Role of IGF-1 pathway in lung fibroblast activation. Respir. Res. 2013;14:102
  Hung CF et al
  2013/01/01
  
• 備考：
  Application: cell culture, Sample Type: Whole Cells
• 参照：
  

• No.： 80
• 文献情報：
  Lee J et al. Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells. Elife 2013;2:e00940
  Lee J et al
  2013/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 81
• 文献情報：
  Elloul S et al. The Adherens Junction Protein Afadin Is an AKT Substrate that Regulates Breast Cancer Cell Migration. Mol. Cancer Res. 2014 Mar;12(3):464-76
  Elloul S et al
  2014/01/01
  
• 備考：
  Application: Stimulation, Sample Type: Cell culture
• 参照：
  

• No.： 82
• 文献情報：
  Shen X et al. Epigallocatechin-3-gallate inhibits cell growth, induces apoptosis and causes S phase arrest in hepatocellular carcinoma by suppressing the AKT pathway. Int. J. Oncol. 2014 Mar;44(3):791-6
  Shen X et al
  2014/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 83
• 文献情報：
  Belzile JP et al. Human cytomegalovirus infection of human embryonic stem cell-derived primitive neural stem cells is restricted at several steps but leads to the persistence of viral DNA. J. Virol. 2014 Apr;88(8):4021-39
  Belzile JP et al
  2014/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 84
• 文献情報：
  Go GW et al. The combined hyperlipidemia caused by impaired Wnt-LRP6 signaling is reversed by Wnt3a rescue. Cell Metab. 2014 Feb;19(2):209-20
  Go GW et al
  2014/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 85
• 文献情報：
  Pei XY et al. Circumvention of Mcl-1-dependent drug resistance by simultaneous Chk1 and MEK1/2 inhibition in human multiple myeloma cells. PLoS ONE 2014;9(3):e89064
  Pei XY et al
  2014/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 86
• 文献情報：
  Wang L et al. Minimally invasive approach to the repair of injured skeletal muscle with a shape-memory scaffold. Mol. Ther. 2014 Aug;22(8):1441-9
  Wang L et al
  2014/01/01
  
• 備考：
  Application: In vivo injection, Sample Type: Whole Organism
• 参照：
  

• No.： 87
• 文献情報：
  Burnight ER et al. CEP290 gene transfer rescues Leber congenital amaurosis cellular phenotype. Gene Ther. 2014 Jul;21(7):662-72
  Burnight ER et al
  2014/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 88
• 文献情報：
  Wang LK et al. MicroRNA-133a suppresses multiple oncogenic membrane receptors and cell invasion in non-small cell lung carcinoma. PLoS ONE 2014;9(5):e96765
  Wang LK et al
  2014/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 89
• 文献情報：
  Mich JK et al. Prospective identification of functionally distinct stem cells and neurosphere-initiating cells in adult mouse forebrain. Elife 2014;3:e02669
  Mich JK et al
  2014/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 90
• 文献情報：
  Li H et al. Ubiquitin ligase Cbl-b represses IGF-I-induced epithelial mesenchymal transition via ZEB2 and microRNA-200c regulation in gastric cancer cells. Mol. Cancer 2014;13:136
  Li H et al
  2014/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 91
• 文献情報：
  Mimura N et al. Selective and potent Akt inhibition triggers anti-myeloma activities and enhances fatal endoplasmic reticulum stress induced by proteasome inhibition. Cancer Res. 2014 Aug;74(16):4458-69
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  2014/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 92
• 文献情報：
  Drexler AL et al. Human IGF1 regulates midgut oxidative stress and epithelial homeostasis to balance lifespan and Plasmodium falciparum resistance in Anopheles stephensi. PLoS Pathog. 2014 Jun;10(6):e1004231
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  2014/01/01
  
• 備考：
  Application: In Vivo, Sample Type: In Vivo
• 参照：
  

• No.： 93
• 文献情報：
  Chinen Y et al. Phosphoinositide protein kinase PDPK1 is a crucial cell signaling mediator in multiple myeloma. Cancer Res. 2014 Dec;74(24):7418-29
  Chinen Y et al
  2014/01/01
  
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  Application: Bioassay, Sample Type: whole cells
• 参照：
  

• No.： 94
• 文献情報：
  Cho YL et al. Specific activation of insulin-like growth factor-1 receptor by ginsenoside Rg5 promotes angiogenesis and vasorelaxation. J. Biol. Chem. 2015 Jan;290(1):467-77
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  2015/01/01
  
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  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 95
• 文献情報：
  Li H et al. Insulin-like growth factor-I induces epithelial to mesenchymal transition via GSK-3β and ZEB2 in the BGC-823 gastric cancer cell line. Oncol Lett 2015 Jan;9(1):143-148
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  2015/01/01
  
• 備考：
  Application: Bioassay, Sample Type: whole cells
• 参照：
  

• No.： 96
• 文献情報：
  Crosley EJ et al. IGFBP-4 and -5 are expressed in first-trimester villi and differentially regulate the migration of HTR-8/SVneo cells. Reprod. Biol. Endocrinol. 2014;12:123
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  2014/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 97
• 文献情報：
  Izumikawa T et al. GlcUAβ1-3Galβ1-3Galβ1-4Xyl(2-O-phosphate) is the preferred substrate for chondroitin N-acetylgalactosaminyltransferase-1. J. Biol. Chem. 2015 Feb;290(9):5438-48
  Izumikawa T et al
  2015/01/01
  
• 備考：
  Application: cell culture, Sample Type: Chrondrocytes
• 参照：
  

• No.： 98
• 文献情報：
  Gori JL et al. Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells. J. Clin. Invest. 2015 Mar;125(3):1243-54
  Gori JL et al
  2015/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 99
• 文献情報：
  Patterson SD et al. Functional EpoR pathway utilization is not detected in primary tumor cells isolated from human breast, non-small cell lung, colorectal, and ovarian tumor tissues. PLoS ONE 2015;10(3):e0122149
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  2015/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 100
• 文献情報：
  Salvucci O et al. EphrinB2 controls vessel pruning through STAT1-JNK3 signalling. Nat Commun 2015;6:6576
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  2015/01/01
  
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  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 101
• 文献情報：
  Bolomsky A et al. Insulin like growth factor binding protein 7 (IGFBP7) expression is linked to poor prognosis but may protect from bone disease in multiple myeloma. J Hematol Oncol 2015;8(1):10
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  2015/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 102
• 文献情報：
  Bell AJ et al. Protein distribution during human erythroblast enucleation in vitro. PLoS ONE 2013;8(4):e60300
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  Application: cell culture, Sample Type: cells
• 参照：
  

• No.： 103
• 文献情報：
  LaFleur DW et al. Monoclonal antibody therapeutics with up to five specificities: functional enhancement through fusion of target-specific peptides. MAbs ;5(2):208-18
  LaFleur DW et al
  
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  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 104
• 文献情報：
  Rawnaq T et al. The multifunctional growth factor midkine promotes proliferation and migration in pancreatic cancer. Mol. Cancer Res. 2014 May;12(5):670-80
  Rawnaq T et al
  2014/01/01
  
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  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 105
• 文献情報：
  Cubbon RM et al. Restoring Akt1 activity in outgrowth endothelial cells from South Asian men rescues vascular reparative potential. Stem Cells 2014 Oct;32(10):2714-23
  Cubbon RM et al
  2014/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 106
• 文献情報：
  Mancini M et al. Co-targeting the IGF system and HIF-1 inhibits migration and invasion by (triple-negative) breast cancer cells. Br. J. Cancer 2014 Jun;110(12):2865-73
  Mancini M et al
  2014/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 107
• 文献情報：
  Liang Z et al. Insulin-like growth factor 1 receptor is a prognostic factor in classical Hodgkin lymphoma. PLoS ONE 2014;9(1):e87474
  Liang Z et al
  2014/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 108
• 文献情報：
  Numasawa-Kuroiwa Y et al. Involvement of ER stress in dysmyelination of Pelizaeus-Merzbacher Disease with PLP1 missense mutations shown by iPSC-derived oligodendrocytes. Stem Cell Reports 2014 May;2(5):648-61
  Numasawa-Kuroiwa Y et al
  2014/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 109
• 文献情報：
  Lee HW et al. Patient-derived xenografts from non-small cell lung cancer brain metastases are valuable translational platforms for the development of personalized targeted therapy. Clin. Cancer Res. 2015 Mar;21(5):1172-82
  Lee HW et al
  2015/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 110
• 文献情報：
  Park M et al. Tonsil-derived mesenchymal stem cells ameliorate CCl4-induced liver fibrosis in mice via autophagy activation. Sci Rep 2015;5:8616
  Park M et al
  2015/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 111
• 文献情報：
  El Khatib MM et al. Tumor-Free Transplantation of Patient-Derived Induced Pluripotent Stem Cell Progeny for Customized Islet Regeneration. Stem Cells Transl Med 2016 May;5(5):694-702
  El Khatib MM et al
  2016/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 112
• 文献情報：
  Bieghs L et al. Abnormal IGF-Binding Protein Profile in the Bone Marrow of Multiple Myeloma Patients. PLoS ONE 2016;11(4):e0154256
  Bieghs L et al
  2016/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Plasma
• 参照：
  

• No.： 113
• 文献情報：
  Kim KT et al. Application of single-cell RNA sequencing in optimizing a combinatorial therapeutic strategy in metastatic renal cell carcinoma. Genome Biol. 2016 Apr;17:80
  Kim KT et al
  2016/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 114
• 文献情報：
  Beyrakhova KA et al. Structural and Functional Investigations of the Effector Protein LpiR1 from Legionella pneumophila. J. Biol. Chem. 2016 Jul;291(30):15767-77
  Beyrakhova KA et al
  2016/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 115
• 文献情報：
  Svalina MN et al. IGF1R as a Key Target in High Risk, Metastatic Medulloblastoma. Sci Rep 2016 Jun;6:27012
  Svalina MN et al
  2016/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 116
• 文献情報：
  Severn CE et al. Polyurethane scaffolds seeded with CD34(+) cells maintain early stem cells whilst also facilitating prolonged egress of haematopoietic progenitors. Sci Rep 2016 Aug;6:32149
  Severn CE et al
  2016/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 117
• 文献情報：
  Boo HJ et al. The tobacco-specific carcinogen-operated calcium channel promotes lung tumorigenesis via IGF2 exocytosis in lung epithelial cells. Nat Commun 2016 Sep;7:12961
  Boo HJ et al
  2016/01/01
  
• 備考：
  Application: Neutralization
• 参照：
  

• No.： 118
• 文献情報：
  Dalton G et al. Soluble klotho binds monosialoganglioside to regulate membrane microdomains and growth factor signaling. Proc. Natl. Acad. Sci. U.S.A. 2017 Jan;114(4):752-757
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  2017/01/01
  
• 備考：
  Application: BioassayCell, Sample Type: Whole Cell
• 参照：
  

• No.： 119
• 文献情報：
  Afratis NA et al. IGF-IR cooperates with ERα to inhibit breast cancer cell aggressiveness by regulating the expression and localisation of ECM molecules. Sci Rep 2017 Jan;7:40138
  Afratis NA et al
  2017/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 120
• 文献情報：
  Lorenz C et al. Human iPSC-Derived Neural Progenitors Are an Effective Drug Discovery Model for Neurological mtDNA Disorders. Cell Stem Cell 2017 May;20(5):659-674.e9
  Lorenz C et al
  2017/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 121
• 文献情報：
  Shao J et al. Experimental Study of the Biological Properties of Human Embryonic Stem Cell-Derived Retinal Progenitor Cells. Sci Rep 2017 Feb;7:42363
  Shao J et al
  2017/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 122
• 文献情報：
  He H et al. Inhibition of Proliferation and Epithelial Mesenchymal Transition in Retinal Pigment Epithelial Cells by Heavy Chain-Hyaluronan/Pentraxin 3. Sci Rep 2017 Mar;7:43736
  He H et al
  2017/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 123
• 文献情報：
  Mercado-Matos J et al. Differential involvement of the microtubule cytoskeleton in insulin receptor substrate 1 (IRS-1) and IRS-2 signaling to AKT determines the response to microtubule disruption in breast carcinoma cells. J. Biol. Chem. 2017 May;292(19)
  Mercado-Matos J et al
  2017/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 124
• 文献情報：
  Tischfield DJ et al. Atypical PKC and Notch Inhibition Differentially Modulate Cortical Interneuron Subclass Fate from Embryonic Stem Cells. Stem Cell Reports 2017 May;8(5):1135-1143
  Tischfield DJ et al
  2017/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：