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在庫・価格 : 2025年07月17日 10時20分 現在

商品名 商品コード メーカー 包装 価格 在庫 リスト
Phospho-Kinase Array Kit, Human, Proteome Profiler
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ARY003B RSDアールアンドディー システムズ
R&D Systems, Inc.
1 kit 本製品は製品内容等が変更されました 変更先製品 追加

在庫・価格 : 2025年07月17日 10時20分 現在

Phospho-Kinase Array Kit, Human, Proteome Profiler

  • 商品コード:ARY003B
  • メーカー:RSD
  • 包装:1kit
  • 本製品は製品内容等が変更されました 変更先製品
使用文献
No. 文献情報 備考 参照
1 Dumitru CA et al. A novel p38-MAPK signaling axis modulates neutrophil biology in head and neck cancer. J. Leukoc. Biol. 2012 Apr;91(4):591-8
Dumitru CA et al
2012/01/01
Sample Type: Cell Lysates PubMed
2 Zhuang G et al. Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway. EMBO J. 2012 Aug;31(17):3513-23
Zhuang G et al
2012/01/01
Sample Type: Cell Lysates PubMed
3 Chandarlapaty S et al. AKT inhibition relieves feedback suppression of receptor tyrosine kinase expression and activity. Cancer Cell 2011 Jan;19(1):58-71
Chandarlapaty S et al
2011/01/01
Sample Type: Cell Lysates PubMed
4 Olszewski U et al. Alterations of phosphoproteins in NCI-H526 small cell lung cancer cells involved in cytotoxicity of cisplatin and titanocene Y. Neoplasia 2012 Sep;14(9):813-22
Olszewski U et al
2012/01/01
Sample Type: Cell Lysates PubMed
5 Shimizu A et al. Netrin-1 promotes glioblastoma cell invasiveness and angiogenesis by multiple pathways including activation of RhoA, cathepsin B, and cAMP-response element-binding protein. J. Biol. Chem. 2013 Jan;288(4):2210-22
Shimizu A et al
2013/01/01
Sample Type: Cell Lysate PubMed
6 Ray KC et al. Heparin-binding epidermal growth factor-like growth factor eliminates constraints on activated Kras to promote rapid onset of pancreatic neoplasia. Oncogene 2014 Feb;33(7):823-31
Ray KC et al
2014/01/01
Application: Array Development, Sample Type: cell cultures PubMed
7 Weidenaar AC et al. Impaired long-term expansion and self-renewal potential of pediatric acute myeloid leukemia-initiating cells by PTK787/ZK 222584. Mol. Cancer Res. 2013 Apr;11(4):339-48
Weidenaar AC et al
2013/01/01
Sample Type: Cell Lysates PubMed
8 Szalm叩s A et al. Activation of Src, Fyn and Yes non-receptor tyrosine kinases in keratinocytes expressing human papillomavirus (HPV) type 16 E7 oncoprotein. Virol. J. 2013;10:79
Szalm叩s A et al
2013/01/01
Sample Type: Cell Lysates PubMed
9 Mir SU et al. Progesterone receptor membrane component 1/Sigma-2 receptor associates with MAP1LC3B and promotes autophagy. Autophagy 2013 Oct;9(10):1566-78
Mir SU et al
2013/01/01
Sample Type: Cell Lysates PubMed
10 Kampen KR et al. Insights in dynamic kinome reprogramming as a consequence of MEK inhibition in MLL-rearranged AML. Leukemia 2014 Mar;28(3):589-99
Kampen KR et al
2014/01/01
Sample Type: bone marrow PubMed
11 Haas DA et al. The inflammatory kinase MAP4K4 promotes reactivation of Kaposi's sarcoma herpesvirus and enhances the invasiveness of infected endothelial cells. PLoS Pathog. 2013;9(11):e1003737
Haas DA et al
2013/01/01
Sample Type: Whole Cells PubMed
12 Drake JM et al. Metastatic castration-resistant prostate cancer reveals intrapatient similarity and interpatient heterogeneity of therapeutic kinase targets. Proc. Natl. Acad. Sci. U.S.A. 2013 Dec;110(49):E4762-9
Drake JM et al
2013/01/01
Sample Type: Homogenized Tissue PubMed
13 Agholme L et al. Proteasome inhibition induces stress kinase dependent transport deficits--implications for Alzheimer's disease. Mol. Cell. Neurosci. 2014 Jan;58:29-39
Agholme L et al
2014/01/01
Sample Type: Total protein PubMed
14 Gu Z et al. Soft matrix is a natural stimulator for cellular invasiveness. Mol. Biol. Cell 2014 Feb;25(4):457-69
Gu Z et al
2014/01/01
Sample Type: Whole Cells PubMed
15 Huck B et al. Elevated protein kinase D3 (PKD3) expression supports proliferation of triple-negative breast cancer cells and contributes to mTORC1-S6K1 pathway activation. J. Biol. Chem. 2014 Feb;289(6):3138-47
Huck B et al
2014/01/01
Sample Type: cell line PubMed
16 Lekawanvijit S et al. The uremic toxin adsorbent AST-120 abrogates cardiorenal injury following myocardial infarction. PLoS ONE 2013;8(12):e83687
Lekawanvijit S et al
2013/01/01
Sample Type: Cell Lysate PubMed
17 Victoni T et al. Roflumilast N-oxide prevents cytokine secretion induced by cigarette smoke combined with LPS through JAK/STAT and ERK1/2 inhibition in airway epithelial cells. PLoS ONE 2014;9(1):e85243
Victoni T et al
2014/01/01
Sample Type: Cell Lysates PubMed
18 Wang LJ et al. Concomitant induction of apoptosis and autophagy by prostate apoptosis response-4 in hypopharyngeal carcinoma cells. Am. J. Pathol. 2014 Feb;184(2):418-30
Wang LJ et al
2014/01/01
Sample Type: Cell Lysate PubMed
19 Bajpe PK et al. A chromatin modifier genetic screen identifies SIRT2 as a modulator of response to targeted therapies through the regulation of MEK kinase activity. Oncogene 2015 Jan;34(4):531-6
Bajpe PK et al
2015/01/01
Sample Type: Cell Lysates PubMed
20 Kim JH et al. The molecular mechanism underlying the proliferating and preconditioning effect of vitamin C on adipose-derived stem cells. Stem Cells Dev. 2014 Jun;23(12):1364-76
Kim JH et al
2014/01/01
Sample Type: Cell Lysate PubMed
21 Yang L et al. Histamine contributes to tissue remodeling via periostin expression. J. Invest. Dermatol. 2014 Aug;134(8):2105-13
Yang L et al
2014/01/01
Sample Type: Whole Cells PubMed
22 Spary LK et al. Enhancement of T cell responses as a result of synergy between lower doses of radiation and T cell stimulation. J. Immunol. 2014 Apr;192(7):3101-10
Spary LK et al
2014/01/01
Sample Type: Whole Cells PubMed
23 Golubkov VS et al. Downstream signaling and genome-wide regulatory effects of PTK7 pseudokinase and its proteolytic fragments in cancer cells. Cell Commun. Signal 2014;12:15
Golubkov VS et al
2014/01/01
Sample Type: Cell Lysates PubMed
24 Li W et al. Sensitizing the therapeutic efficacy of taxol with shikonin in human breast cancer cells. PLoS ONE 2014;9(4):e94079
Li W et al
2014/01/01
Sample Type: Cell Lysate PubMed
25 Jokela TA et al. Extracellular UDP-glucose activates P2Y14 Receptor and Induces Signal Transducer and Activator of Transcription 3 (STAT3) Tyr705 phosphorylation and binding to hyaluronan synthase 2 (HAS2) promoter, stimulating hyaluronan synthesis of ker
Jokela TA et al
2014/01/01
Sample Type: Cell Lysates PubMed
26 Naspi A et al. Insulin-like-growth-factor-binding-protein-3 (IGFBP-3) contrasts melanoma progression in vitro and in vivo. PLoS ONE 2014;9(6):e98641
Naspi A et al
2014/01/01
Sample Type: Cell Lysates PubMed
27 Large MJ et al. The epidermal growth factor receptor critically regulates endometrial function during early pregnancy. PLoS Genet. 2014 Jun;10(6):e1004451
Large MJ et al
2014/01/01
Sample Type: Cell Lysate PubMed
28 Sinkevicius KW et al. Neurotrophin receptor TrkB promotes lung adenocarcinoma metastasis. Proc. Natl. Acad. Sci. U.S.A. 2014 Jul;111(28):10299-304
Sinkevicius KW et al
2014/01/01
Sample Type: Cell Lysates PubMed
29 Virtanen SS et al. Adenosine inhibits tumor cell invasion via receptor-independent mechanisms. Mol. Cancer Res. 2014 Dec;12(12):1863-74
Virtanen SS et al
2014/01/01
Sample Type: Whole Cells PubMed
30 Lee E et al. Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis. Nat Commun 2014;5:4715
Lee E et al
2014/01/01
Sample Type: Cell Culture Supernates PubMed
31 Lapeire L et al. Cancer-associated adipose tissue promotes breast cancer progression by paracrine oncostatin M and Jak/STAT3 signaling. Cancer Res. 2014 Dec;74(23):6806-19
Lapeire L et al
2014/01/01
Sample Type: Cell Lysates PubMed
32 Ranayhossaini DJ et al. EGF potentiation of VEGF production is cell density dependent in H292 EGFR wild type NSCLC cell line. Int J Mol Sci 2014;15(10):17686-704
Ranayhossaini DJ et al
2014/01/01
Sample Type: Whole Cells PubMed
33 Cho YL et al. Specific activation of insulin-like growth factor-1 receptor by ginsenoside Rg5 promotes angiogenesis and vasorelaxation. J. Biol. Chem. 2015 Jan;290(1):467-77
Cho YL et al
2015/01/01
Sample Type: Cell Lysate PubMed
34 Tseng PC et al. An increase in integrin-linked kinase non-canonically confers NF-κB-mediated growth advantages to gastric cancer cells by activating ERK1/2. Cell Commun. Signal 2014;12:69
Tseng PC et al
2014/01/01
Sample Type: Cell Lysates PubMed
35 Bruneau S et al. Loss of DGKε induces endothelial cell activation and death independently of complement activation. Blood 2015 Feb;125(6):1038-46
Bruneau S et al
2015/01/01
Sample Type: Cell Lysates PubMed
36 Atefi M et al. Combination of pan-RAF and MEK inhibitors in NRAS mutant melanoma. Mol. Cancer 2015;14:27
Atefi M et al
2015/01/01
Sample Type: Whole Cells PubMed
37 Man J et al. Hyperthermia Sensitizes Glioma Stem-like Cells to Radiation by Inhibiting AKT Signaling. Cancer Res. 2015 Apr;75(8):1760-9
Man J et al
2015/01/01
Sample Type: Cell Lysates PubMed
38 Laukkanen MO et al. Extracellular superoxide dismutase regulates the expression of small gtpase regulatory proteins GEFs, GAPs, and GDI. PLoS ONE 2015;10(3):e0121441
Laukkanen MO et al
2015/01/01
Sample Type: Cell Lysates PubMed
39 Liu K et al. Sunlight UV-induced skin cancer relies upon activation of the p38α signaling pathway. Cancer Res. 2013 Apr;73(7):2181-8
Liu K et al
2013/01/01
Sample Type: Cell Lysate PubMed
40 Song W et al. JNK signaling mediates EPHA2-dependent tumor cell proliferation, motility, and cancer stem cell-like properties in non-small cell lung cancer. Cancer Res. 2014 May;74(9):2444-54
Song W et al
2014/01/01
Sample Type: Cell Lysates PubMed
41 Marra P et al. IL15RA drives antagonistic mechanisms of cancer development and immune control in lymphocyte-enriched triple-negative breast cancers. Cancer Res. 2014 Sep;74(17):4908-21
Marra P et al
2014/01/01
Sample Type: Cell Lysates PubMed
42 Mailly L et al. Clearance of persistent hepatitis C virus infection in humanized mice using a claudin-1-targeting monoclonal antibody. Nat. Biotechnol. 2015 May;33(5):549-54
Mailly L et al
2015/01/01
Sample Type: Cell Lysates PubMed
43 Chang BH et al. YM155 potently kills acute lymphoblastic leukemia cells through activation of the DNA damage pathway. J Hematol Oncol 2015;8:39
Chang BH et al
2015/01/01
Sample Type: Cell Lysates PubMed
44 Hansen FC et al. The Thrombin-Derived Host Defense Peptide GKY25 Inhibits Endotoxin-Induced Responses through Interactions with Lipopolysaccharide and Macrophages/Monocytes. J. Immunol. 2015 Jun;194(11):5397-406
Hansen FC et al
2015/01/01
Sample Type: Cell Lysates PubMed
45 Singh A et al. Targeted inhibition of MEK1 by cobimetinib leads to differentiation and apoptosis in neuroblastoma cells. J. Exp. Clin. Cancer Res. 2015;34:104
Singh A et al
2015/01/01
Sample Type: Cell Lysates PubMed
46 Paggetti J et al. Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts. Blood 2015 Aug;126(9):1106-17
Paggetti J et al
2015/01/01
Sample Type: Cell Lysates PubMed
47 Yamada T et al. Akt Kinase-Interacting Protein 1 Signals through CREB to Drive Diffuse Malignant Mesothelioma. Cancer Res. 2015 Oct;75(19):4188-97
Yamada T et al
2015/01/01
Sample Type: Cell Lysates PubMed
48 Purushothaman A et al. Fibronectin on the Surface of Myeloma Cell-derived Exosomes Mediates Exosome-Cell Interactions. J. Biol. Chem. 2016 Jan;291(4):1652-63
Purushothaman A et al
2016/01/01
Sample Type: Cell Lysates PubMed
49 Skolekova S et al. Cisplatin-induced mesenchymal stromal cells-mediated mechanism contributing to decreased antitumor effect in breast cancer cells. Cell Commun. Signal 2016;14:4
Skolekova S et al
2016/01/01
Sample Type: Cell Lysates PubMed
50 Sento S et al. Application of a Persistent Heparin Treatment Inhibits the Malignant Potential of Oral Squamous Carcinoma Cells Induced by Tumor Cell-Derived Exosomes. PLoS ONE 2016;11(2):e0148454
Sento S et al
2016/01/01
Sample Type: Cell Lysates PubMed
51 Dreses-Werringloer U et al. CALHM1 controls the Ca²⁺-dependent MEK, ERK, RSK and MSK signaling cascade in neurons. J. Cell. Sci. 2013 Mar;126(Pt 5):1199-206
Dreses-Werringloer U et al
2013/01/01
Sample Type: Cell Lysates PubMed
52 P探lajeva J et al. Glioma-derived macrophage migration inhibitory factor (MIF) promotes mast cell recruitment in a STAT5-dependent manner. Mol Oncol 2014 Feb;8(1):50-8
P探lajeva J et al
2014/01/01
Sample Type: Cell Lysates PubMed
53 Raimondi C et al. Imatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1-dependent ABL1 activation in endothelial cells. J. Exp. Med. 2014 Jun;211(6):1167-83
Raimondi C et al
2014/01/01
Sample Type: Cell Lysates PubMed
54 Speakman CM et al. Elevated O-GlcNAc levels activate epigenetically repressed genes and delay mouse ESC differentiation without affecting naïve to primed cell transition. Stem Cells 2014 Oct;32(10):2605-15
Speakman CM et al
2014/01/01
Sample Type: Cell Lysates PubMed
55 Eggink LL et al. A Peptide Mimetic of 5-Acetylneuraminic Acid-Galactose Binds with High Avidity to Siglecs and NKG2D. PLoS ONE 2015;10(6):e0130532
Eggink LL et al
2015/01/01
Sample Type: Cell Lysates PubMed
56 Wculek SK et al. Neutrophils support lung colonization of metastasis-initiating breast cancer cells. Nature 2015 Dec;528(7582):413-7
Wculek SK et al
2015/01/01
Sample Type: Cell Lysates PubMed
57 Ahn SH et al. Necrotic cells influence migration and invasion of glioblastoma via NF-κB/AP-1-mediated IL-8 regulation. Sci Rep 2016 Apr;6:24552
Ahn SH et al
2016/01/01
Sample Type: Cell Lysates PubMed
58 Derlet A et al. Metabolism Regulates Cellular Functions of Bone Marrow-Derived Cells used for Cardiac Therapy. Stem Cells 2016 Aug;34(8):2236-48
Derlet A et al
2016/01/01
Sample Type: Cell Lysates PubMed
59 Bullova P et al. Hypoxia potentiates the cytotoxic effect of piperlongumine in pheochromocytoma models. Oncotarget 2016 Jun;7(26):40531-40545
Bullova P et al
2016/01/01
Sample Type: Cell Lysates PubMed
60 Gu Y et al. BRCA1-deficient breast cancer cell lines are resistant to MEK inhibitors and show distinct sensitivities to 6-thioguanine. Sci Rep 2016;6:28217
Gu Y et al
2016/01/01
Sample Type: Cell Lysates PubMed
61 Barquilla A et al. Protein kinase A can block EphA2 receptor-mediated cell repulsion by increasing EphA2 S897 phosphorylation. Mol. Biol. Cell 2016 Sep;27(17):2757-70
Barquilla A et al
2016/01/01
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62 Sauer M et al. CBP/p300 acetyltransferases regulate the expression of NKG2D ligands on tumor cells. Oncogene 2017 Feb;36(7):933-941
Sauer M et al
2017/01/01
Sample Type: Cell Lysates PubMed
63 Flegel C et al. Characterization of non-olfactory GPCRs in human sperm with a focus on GPR18. Sci Rep 2016 Aug;6:32255
Flegel C et al
2016/01/01
Sample Type: Cell Culture Supernates PubMed
64 Chi M et al. Phosphorylation of calcium/calmodulin-stimulated protein kinase II at T286 enhances invasion and migration of human breast cancer cells. Sci Rep 2016 Sep;6:33132
Chi M et al
2016/01/01
Sample Type: Cell Lysates PubMed
65 Bezzerri V et al. New insights into the Shwachman-Diamond Syndrome-related haematological disorder: hyper-activation of mTOR and STAT3 in leukocytes. Sci Rep 2016 Sep;6:33165
Bezzerri V et al
2016/01/01
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66 Patel AB et al. Neurotensin stimulates sortilin and mTOR in human microglia inhibitable by methoxyluteolin, a potential therapeutic target for autism. Proc. Natl. Acad. Sci. U.S.A. 2016 Sep;
Patel AB et al
2016/01/01
Sample Type: Cell Lysates PubMed
67 Satelli A et al. Potential Function of Exogenous Vimentin on the Activation of Wnt Signaling Pathway in Cancer Cells. J Cancer 2016;7(13):1824-1832
Satelli A et al
2016/01/01
Sample Type: Cell Lysates PubMed
68 O'Hara SD et al. Murine Polyomavirus Cell Surface Receptors Activate Distinct Signaling Pathways Required for Infection. MBio 2016 Nov;7(6)
O'Hara SD et al
2016/01/01
Sample Type: Cell Lysates PubMed
69 Zhang SR et al. Capilliposide from Lysimachia capillipes inhibits AKT activation and restores gefitinib sensitivity in human non-small cell lung cancer cells with acquired gefitinib resistance. Acta Pharmacol. Sin. 2017 Jan;38(1):100-109
Zhang SR et al
2017/01/01
Sample Type: Cell Lysates PubMed
70 Fotouhi Ghiam A et al. Long non-coding RNA urothelial carcinoma associated 1 (UCA1) mediates radiation response in prostate cancer. Oncotarget 2017 Jan;8(3):4668-4689
Fotouhi Ghiam A et al
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71 Nadeau SA et al. Structural Determinants of the Gain-of-Function Phenotype of Human Leukemia-associated Mutant CBL Oncogene. J. Biol. Chem. 2017 Mar;292(9):3666-3682
Nadeau SA et al
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Sample Type: Cell Lysates PubMed
72 Bank坦 Z et al. Induction and Differentiation of IL-10-Producing Regulatory B Cells from Healthy Blood Donors and Rheumatoid Arthritis Patients. J. Immunol. 2017 Feb;198(4):1512-1520
Bank坦 Z et al
2017/01/01
Sample Type: Whole Cells PubMed
73 Lee HJ et al. Ras-MEK Signaling Mediates a Critical Chk1-Dependent DNA Damage Response in Cancer Cells. Mol. Cancer Ther. 2017 Apr;16(4):694-704
Lee HJ et al
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Sample Type: Cell Lysates PubMed
74 Kuan II et al. EpEX/EpCAM and Oct4 or Klf4 alone are sufficient to generate induced pluripotent stem cells through STAT3 and HIF2α. Sci Rep 2017 Feb;7:41852
Kuan II et al
2017/01/01
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75 Wladis EJ et al. Activation of p38 and Erk Mitogen-Activated Protein Kinases Signaling in Ocular Rosacea. Invest. Ophthalmol. Vis. Sci. 2017 Feb;58(2):843-848
Wladis EJ et al
2017/01/01
Sample Type: Tissue Homogenates PubMed
76 Buchanan PC et al. Ectodomain shedding of the cell adhesion molecule Nectin-4 in ovarian cancer is mediated by ADAM10 and ADAM17. J. Biol. Chem. 2017 Apr;292(15):6339-6351
Buchanan PC et al
2017/01/01
Sample Type: cell supernates PubMed
77 Kalyvianaki K et al. Antagonizing effects of membrane-acting androgens on the eicosanoid receptor OXER1 in prostate cancer. Sci Rep 2017 Mar;7:44418
Kalyvianaki K et al
2017/01/01
Sample Type: Cell Lysates PubMed
78 Colomb F et al. Galectin-3 interacts with the cell-surface glycoprotein CD146 (MCAM, MUC18) and induces secretion of metastasis-promoting cytokines from vascular endothelial cells. J. Biol. Chem. 2017 May;292(20):8381-8389
Colomb F et al
2017/01/01
Sample Type: Cell Lysates PubMed
79 Zhou Z et al. The HIV-1 viral synapse signals human foreskin keratinocytes to secrete thymic stromal lymphopoietin facilitating HIV-1 foreskin entry. Mucosal Immunol 2017 Apr;
Zhou Z et al
2017/01/01
Sample Type: Cell Lysates PubMed
80 Chang CH et al. Secreted Protein Acidic and Rich in Cysteine (SPARC) Enhances Cell Proliferation, Migration, and Epithelial Mesenchymal Transition, and SPARC Expression is Associated with Tumor Grade in Head and Neck Cancer. Int J Mol Sci 2017 Jul;18(7)
Chang CH et al
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81 Carretero J et al. Integrative genomic and proteomic analyses identify targets for Lkb1-deficient metastatic lung tumors. Cancer Cell 2010 Jun;17(6):547-59
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Species: Human PubMed
82 Yang P et al. Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension. Circ
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Species: Human PubMed
83 Chen W et al. WNK1 kinase and its partners Akt, SGK1 and NBC-family Na<sup>+</sup>/HCO3<sup>-</sup> cotransporters are potential therapeutic targets for glioblastoma stem-like cells linked to Bisacodyl signaling. Oncotarget 2018 Jun;9(43):27197-27219
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Species: Human PubMed
84 . ;

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85 Dewaele B et al. Coactivated platelet-derived growth factor receptor {alpha} and epidermal growth factor receptor are potential therapeutic targets in intimal sarcoma. Cancer Res. 2010 Sep;70(18):7304-14
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2010/01/01
Species: Human PubMed
86 Davies KD et al. Resistance to ROS1 inhibition mediated by EGFR pathway activation in non-small cell lung cancer. PLoS ONE 2013;8(12):e82236
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Species: Human PubMed
87 Xiao K et al. Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR). Proc. Natl. Acad. Sci. U.S.A. 2010 Aug;107(34):15299-304
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88 Fritz V et al. Abrogation of de novo lipogenesis by stearoyl-CoA desaturase 1 inhibition interferes with oncogenic signaling and blocks prostate cancer progression in mice. Mol. Cancer Ther. 2010 Jun;9(6):1740-54
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Species: Human PubMed
89 Shien K et al. JAK1/STAT3 Activation through a Proinflammatory Cytokine Pathway Leads to Resistance to Molecularly Targeted Therapy in Non-Small Cell Lung Cancer. Mol. Cancer Ther. 2017 Oct;16(10):2234-2245
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Species: Human PubMed
90 Lee H et al. Isorhynchophylline, a Potent Plant Alkaloid, Induces Apoptotic and Anti-Metastatic Effects in Human Hepatocellular Carcinoma Cells through the Modulation of Diverse Cell Signaling Cascades. Int J Mol Sci 2017 May;18(5)
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Species: Human PubMed
91 テ〕varez-Teijeiro S et al. Dysregulation of Mir-196b in Head and Neck Cancers Leads to Pleiotropic Effects in the Tumor Cells and Surrounding Stromal Fibroblasts. Sci Rep 2017 Dec;7(1):17785
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92 Keller S et al. Evaluation of epidermal growth factor receptor signaling effects in gastric cancer cell lines by detailed motility-focused phenotypic characterization linked with molecular analysis. BMC Cancer 2017 12;17(1):845
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93 Iida M et al. Overcoming acquired resistance to cetuximab by dual targeting HER family receptors with antibody-based therapy. Mol. Cancer 2014;13:242
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94 Heger J et al. JDP2 overexpression provokes cardiac dysfunction in mice. Sci Rep 2018 May;8(1):7647
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95 Chen PC et al. Activation of multiple signaling pathways causes developmental defects in mice with a Noonan syndromeテ「竄ャ窶彗ssociated Sos1 mutation. J. Clin. Invest. 2010 Dec;120(12):4353-65
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Species: Mouse PubMed
96 Co谷ffier M et al. Influence of leucine on protein metabolism, phosphokinase expression, and cell proliferation in human duodenum1,3. Am. J. Clin. Nutr. 2011 Jun;93(6):1255-62
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97 B辿nard L et al. Cardiac Stim1 Silencing Impairs Adaptive Hypertrophy and Promotes Heart Failure Through Inactivation of mTORC2/Akt Signaling. Circulation 2016 Apr;133(15):1458-71; discussion 1471
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98 Heavey S et al. Development and characterisation of a panel of phosphatidylinositide 3-kinase - mammalian target of rapamycin inhibitor resistant lung cancer cell lines. Sci Rep 2018 Jan;8(1):1652
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99 Kuppusamy P et al. Concomitant activation of ETS-like transcription factor-1 and Death Receptor-5 via extracellular signal-regulated kinase in withaferin A-mediated inhibition of hepatocarcinogenesis in mice. Sci Rep 2017 Dec;7(1):17943
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Species: Human PubMed
100 Couty JP et al. Kaposi&#39;s sarcoma-associated herpesvirus-G protein-coupled receptor-expressing endothelial cells exhibit reduced migration and stimulated chemotaxis by chemokine inverse agonists. J. Pharmacol. Exp. Ther. 2009 Jun;329(3):1142-7
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101 Zhao D et al. Cytoplasmic p27 promotes epithelial-mesenchymal transition and tumor metastasis via STAT3-mediated Twist1 upregulation. Oncogene 2015 Oct;34(43):5447-59
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Species: Human PubMed
102 Santiago-O&#39;Farrill JM et al. Phosphorylated heat shock protein 27 as a potential biomarker to predict the role of chemotherapy-induced autophagy in osteosarcoma response to therapy. Oncotarget 2018 Jan;9(2):1602-1616
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103 Vingtdeux V et al. AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism. J. Biol. Chem. 2010 Mar;285(12):9100-13
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104 Islam S et al. Disruption of Aneuploidy and Senescence Induced by Aurora Inhibition Promotes Intrinsic Apoptosis in Double Hit or Double Expressor Diffuse Large B-cell Lymphomas. Mol. Cancer Ther. 2017 Oct;16(10):2083-2093
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105 Carriero MV et al. Retro-inverso Urokinase Receptor Antagonists for the Treatment of Metastatic Sarcomas. Sci Rep 2017 05;7(1):1312
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106 Stegeman H et al. Combining radiotherapy with MEK1/2, STAT5 or STAT6 inhibition reduces survival of head and neck cancer lines. Mol. Cancer 2013;12(1):133
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Species: Human PubMed
107 Zhang X et al. YM155 decreases radiation-induced invasion and reverses epithelial-mesenchymal transition by targeting STAT3 in glioblastoma. J Transl Med 2018 Mar;16(1):79
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2018/01/01
Species: Human PubMed
108 Li A et al. Overexpression of CXCL5 is associated with poor survival in patients with pancreatic cancer. Am. J. Pathol. 2011 Mar;178(3):1340-9
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    Sample Type: bone marrow
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    PubMed
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    Haas DA et al. The inflammatory kinase MAP4K4 promotes reactivation of Kaposi&#39;s sarcoma herpesvirus and enhances the invasiveness of infected endothelial cells. PLoS Pathog. 2013;9(11):e1003737
    Haas DA et al
    2013/01/01
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    Sample Type: Whole Cells
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    PubMed
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    Drake JM et al. Metastatic castration-resistant prostate cancer reveals intrapatient similarity and interpatient heterogeneity of therapeutic kinase targets. Proc. Natl. Acad. Sci. U.S.A. 2013 Dec;110(49):E4762-9
    Drake JM et al
    2013/01/01
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    Sample Type: Homogenized Tissue
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    PubMed
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    Agholme L et al. Proteasome inhibition induces stress kinase dependent transport deficits--implications for Alzheimer&#39;s disease. Mol. Cell. Neurosci. 2014 Jan;58:29-39
    Agholme L et al
    2014/01/01
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    Sample Type: Total protein
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    PubMed
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    Gu Z et al. Soft matrix is a natural stimulator for cellular invasiveness. Mol. Biol. Cell 2014 Feb;25(4):457-69
    Gu Z et al
    2014/01/01
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    Sample Type: Whole Cells
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    PubMed
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    Huck B et al. Elevated protein kinase D3 (PKD3) expression supports proliferation of triple-negative breast cancer cells and contributes to mTORC1-S6K1 pathway activation. J. Biol. Chem. 2014 Feb;289(6):3138-47
    Huck B et al
    2014/01/01
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    Sample Type: cell line
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    PubMed
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    Lekawanvijit S et al. The uremic toxin adsorbent AST-120 abrogates cardiorenal injury following myocardial infarction. PLoS ONE 2013;8(12):e83687
    Lekawanvijit S et al
    2013/01/01
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    Sample Type: Cell Lysate
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    PubMed
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    Victoni T et al. Roflumilast N-oxide prevents cytokine secretion induced by cigarette smoke combined with LPS through JAK/STAT and ERK1/2 inhibition in airway epithelial cells. PLoS ONE 2014;9(1):e85243
    Victoni T et al
    2014/01/01
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    Sample Type: Cell Lysates
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    PubMed
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    Wang LJ et al. Concomitant induction of apoptosis and autophagy by prostate apoptosis response-4 in hypopharyngeal carcinoma cells. Am. J. Pathol. 2014 Feb;184(2):418-30
    Wang LJ et al
    2014/01/01
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    PubMed
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    Bajpe PK et al. A chromatin modifier genetic screen identifies SIRT2 as a modulator of response to targeted therapies through the regulation of MEK kinase activity. Oncogene 2015 Jan;34(4):531-6
    Bajpe PK et al
    2015/01/01
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    Sample Type: Cell Lysates
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    PubMed
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    Kim JH et al. The molecular mechanism underlying the proliferating and preconditioning effect of vitamin C on adipose-derived stem cells. Stem Cells Dev. 2014 Jun;23(12):1364-76
    Kim JH et al
    2014/01/01
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    PubMed
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    Yang L et al. Histamine contributes to tissue remodeling via periostin expression. J. Invest. Dermatol. 2014 Aug;134(8):2105-13
    Yang L et al
    2014/01/01
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    Sample Type: Whole Cells
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    PubMed
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    Spary LK et al. Enhancement of T cell responses as a result of synergy between lower doses of radiation and T cell stimulation. J. Immunol. 2014 Apr;192(7):3101-10
    Spary LK et al
    2014/01/01
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    Sample Type: Whole Cells
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    PubMed
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    Golubkov VS et al. Downstream signaling and genome-wide regulatory effects of PTK7 pseudokinase and its proteolytic fragments in cancer cells. Cell Commun. Signal 2014;12:15
    Golubkov VS et al
    2014/01/01
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    Sample Type: Cell Lysates
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    PubMed
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    Li W et al. Sensitizing the therapeutic efficacy of taxol with shikonin in human breast cancer cells. PLoS ONE 2014;9(4):e94079
    Li W et al
    2014/01/01
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    Sample Type: Cell Lysate
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    PubMed
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    Jokela TA et al. Extracellular UDP-glucose activates P2Y14 Receptor and Induces Signal Transducer and Activator of Transcription 3 (STAT3) Tyr705 phosphorylation and binding to hyaluronan synthase 2 (HAS2) promoter, stimulating hyaluronan synthesis of ker
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    2014/01/01
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    Sample Type: Cell Lysates
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    PubMed
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    Naspi A et al. Insulin-like-growth-factor-binding-protein-3 (IGFBP-3) contrasts melanoma progression in vitro and in vivo. PLoS ONE 2014;9(6):e98641
    Naspi A et al
    2014/01/01
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    Sample Type: Cell Lysates
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    PubMed
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    Large MJ et al. The epidermal growth factor receptor critically regulates endometrial function during early pregnancy. PLoS Genet. 2014 Jun;10(6):e1004451
    Large MJ et al
    2014/01/01
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    Sample Type: Cell Lysate
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    Sinkevicius KW et al. Neurotrophin receptor TrkB promotes lung adenocarcinoma metastasis. Proc. Natl. Acad. Sci. U.S.A. 2014 Jul;111(28):10299-304
    Sinkevicius KW et al
    2014/01/01
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    Sample Type: Cell Lysates
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    Virtanen SS et al. Adenosine inhibits tumor cell invasion via receptor-independent mechanisms. Mol. Cancer Res. 2014 Dec;12(12):1863-74
    Virtanen SS et al
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    Sample Type: Whole Cells
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    Lee E et al. Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis. Nat Commun 2014;5:4715
    Lee E et al
    2014/01/01
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    Sample Type: Cell Culture Supernates
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    Lapeire L et al. Cancer-associated adipose tissue promotes breast cancer progression by paracrine oncostatin M and Jak/STAT3 signaling. Cancer Res. 2014 Dec;74(23):6806-19
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    Sample Type: Cell Lysates
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    Ranayhossaini DJ et al. EGF potentiation of VEGF production is cell density dependent in H292 EGFR wild type NSCLC cell line. Int J Mol Sci 2014;15(10):17686-704
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    Sample Type: Whole Cells
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    Cho YL et al. Specific activation of insulin-like growth factor-1 receptor by ginsenoside Rg5 promotes angiogenesis and vasorelaxation. J. Biol. Chem. 2015 Jan;290(1):467-77
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    Sample Type: Cell Lysate
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    Tseng PC et al. An increase in integrin-linked kinase non-canonically confers NF-&#x3BA;B-mediated growth advantages to gastric cancer cells by activating ERK1/2. Cell Commun. Signal 2014;12:69
    Tseng PC et al
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    Sample Type: Cell Lysates
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    Bruneau S et al. Loss of DGK&#x3B5; induces endothelial cell activation and death independently of complement activation. Blood 2015 Feb;125(6):1038-46
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    Atefi M et al. Combination of pan-RAF and MEK inhibitors in NRAS mutant melanoma. Mol. Cancer 2015;14:27
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    Sample Type: Whole Cells
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    Man J et al. Hyperthermia Sensitizes Glioma Stem-like Cells to Radiation by Inhibiting AKT Signaling. Cancer Res. 2015 Apr;75(8):1760-9
    Man J et al
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    Laukkanen MO et al. Extracellular superoxide dismutase regulates the expression of small gtpase regulatory proteins GEFs, GAPs, and GDI. PLoS ONE 2015;10(3):e0121441
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    Sample Type: Cell Lysates
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    Liu K et al. Sunlight UV-induced skin cancer relies upon activation of the p38&#x3B1; signaling pathway. Cancer Res. 2013 Apr;73(7):2181-8
    Liu K et al
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    Sample Type: Cell Lysate
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    Song W et al. JNK signaling mediates EPHA2-dependent tumor cell proliferation, motility, and cancer stem cell-like properties in non-small cell lung cancer. Cancer Res. 2014 May;74(9):2444-54
    Song W et al
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    Marra P et al. IL15RA drives antagonistic mechanisms of cancer development and immune control in lymphocyte-enriched triple-negative breast cancers. Cancer Res. 2014 Sep;74(17):4908-21
    Marra P et al
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    Mailly L et al. Clearance of persistent hepatitis C virus infection in humanized mice using a claudin-1-targeting monoclonal antibody. Nat. Biotechnol. 2015 May;33(5):549-54
    Mailly L et al
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    Sample Type: Cell Lysates
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    Chang BH et al. YM155 potently kills acute lymphoblastic leukemia cells through activation of the DNA damage pathway. J Hematol Oncol 2015;8:39
    Chang BH et al
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    Hansen FC et al. The Thrombin-Derived Host Defense Peptide GKY25 Inhibits Endotoxin-Induced Responses through Interactions with Lipopolysaccharide and Macrophages/Monocytes. J. Immunol. 2015 Jun;194(11):5397-406
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    Sample Type: Cell Lysates
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    Singh A et al. Targeted inhibition of MEK1 by cobimetinib leads to differentiation and apoptosis in neuroblastoma cells. J. Exp. Clin. Cancer Res. 2015;34:104
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    Sample Type: Cell Lysates
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    Paggetti J et al. Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts. Blood 2015 Aug;126(9):1106-17
    Paggetti J et al
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    Sample Type: Cell Lysates
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    PubMed
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  • 文献情報:
    Yamada T et al. Akt Kinase-Interacting Protein 1 Signals through CREB to Drive Diffuse Malignant Mesothelioma. Cancer Res. 2015 Oct;75(19):4188-97
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    Sample Type: Cell Lysates
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    PubMed
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    Purushothaman A et al. Fibronectin on the Surface of Myeloma Cell-derived Exosomes Mediates Exosome-Cell Interactions. J. Biol. Chem. 2016 Jan;291(4):1652-63
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    Sample Type: Cell Lysates
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    PubMed
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    Skolekova S et al. Cisplatin-induced mesenchymal stromal cells-mediated mechanism contributing to decreased antitumor effect in breast cancer cells. Cell Commun. Signal 2016;14:4
    Skolekova S et al
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    Sample Type: Cell Lysates
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    PubMed
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  • 文献情報:
    Sento S et al. Application of a Persistent Heparin Treatment Inhibits the Malignant Potential of Oral Squamous Carcinoma Cells Induced by Tumor Cell-Derived Exosomes. PLoS ONE 2016;11(2):e0148454
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    Sample Type: Cell Lysates
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    Dreses-Werringloer U et al. CALHM1 controls the Ca&#xB2;&#x207A;-dependent MEK, ERK, RSK and MSK signaling cascade in neurons. J. Cell. Sci. 2013 Mar;126(Pt 5):1199-206
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    Sample Type: Cell Lysates
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    P探lajeva J et al. Glioma-derived macrophage migration inhibitory factor (MIF) promotes mast cell recruitment in a STAT5-dependent manner. Mol Oncol 2014 Feb;8(1):50-8
    P探lajeva J et al
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    Sample Type: Cell Lysates
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    Raimondi C et al. Imatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1-dependent ABL1 activation in endothelial cells. J. Exp. Med. 2014 Jun;211(6):1167-83
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    Sample Type: Cell Lysates
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    Speakman CM et al. Elevated O-GlcNAc levels activate epigenetically repressed genes and delay mouse ESC differentiation without affecting na&#xEF;ve to primed cell transition. Stem Cells 2014 Oct;32(10):2605-15
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    Sample Type: Cell Lysates
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    PubMed
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    Eggink LL et al. A Peptide Mimetic of 5-Acetylneuraminic Acid-Galactose Binds with High Avidity to Siglecs and NKG2D. PLoS ONE 2015;10(6):e0130532
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    Sample Type: Cell Lysates
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    PubMed
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    Wculek SK et al. Neutrophils support lung colonization of metastasis-initiating breast cancer cells. Nature 2015 Dec;528(7582):413-7
    Wculek SK et al
    2015/01/01
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    Sample Type: Cell Lysates
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    PubMed
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    Ahn SH et al. Necrotic cells influence migration and invasion of glioblastoma via NF-&#x3BA;B/AP-1-mediated IL-8 regulation. Sci Rep 2016 Apr;6:24552
    Ahn SH et al
    2016/01/01
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    Sample Type: Cell Lysates
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    PubMed
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    Derlet A et al. Metabolism Regulates Cellular Functions of Bone Marrow-Derived Cells used for Cardiac Therapy. Stem Cells 2016 Aug;34(8):2236-48
    Derlet A et al
    2016/01/01
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    Sample Type: Cell Lysates
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    PubMed
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    Bullova P et al. Hypoxia potentiates the cytotoxic effect of piperlongumine in pheochromocytoma models. Oncotarget 2016 Jun;7(26):40531-40545
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    Sample Type: Cell Lysates
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    PubMed
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  • 文献情報:
    Gu Y et al. BRCA1-deficient breast cancer cell lines are resistant to MEK inhibitors and show distinct sensitivities to 6-thioguanine. Sci Rep 2016;6:28217
    Gu Y et al
    2016/01/01
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    Sample Type: Cell Lysates
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    PubMed
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  • 文献情報:
    Barquilla A et al. Protein kinase A can block EphA2 receptor-mediated cell repulsion by increasing EphA2 S897 phosphorylation. Mol. Biol. Cell 2016 Sep;27(17):2757-70
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    2016/01/01
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    Sample Type: Cell Lysates
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    PubMed
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    Sauer M et al. CBP/p300 acetyltransferases regulate the expression of NKG2D ligands on tumor cells. Oncogene 2017 Feb;36(7):933-941
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    Sample Type: Cell Lysates
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    PubMed
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  • 文献情報:
    Flegel C et al. Characterization of non-olfactory GPCRs in human sperm with a focus on GPR18. Sci Rep 2016 Aug;6:32255
    Flegel C et al
    2016/01/01
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    Sample Type: Cell Culture Supernates
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    PubMed
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  • 文献情報:
    Chi M et al. Phosphorylation of calcium/calmodulin-stimulated protein kinase II at T286 enhances invasion and migration of human breast cancer cells. Sci Rep 2016 Sep;6:33132
    Chi M et al
    2016/01/01
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    Sample Type: Cell Lysates
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    PubMed
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  • 文献情報:
    Bezzerri V et al. New insights into the Shwachman-Diamond Syndrome-related haematological disorder: hyper-activation of mTOR and STAT3 in leukocytes. Sci Rep 2016 Sep;6:33165
    Bezzerri V et al
    2016/01/01
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    Sample Type: Cell Lysates
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    PubMed
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    Patel AB et al. Neurotensin stimulates sortilin and mTOR in human microglia inhibitable by methoxyluteolin, a potential therapeutic target for autism. Proc. Natl. Acad. Sci. U.S.A. 2016 Sep;
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    Sample Type: Cell Lysates
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    PubMed
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    Satelli A et al. Potential Function of Exogenous Vimentin on the Activation of Wnt Signaling Pathway in Cancer Cells. J Cancer 2016;7(13):1824-1832
    Satelli A et al
    2016/01/01
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    Sample Type: Cell Lysates
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    PubMed
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    O&#39;Hara SD et al. Murine Polyomavirus Cell Surface Receptors Activate Distinct Signaling Pathways Required for Infection. MBio 2016 Nov;7(6)
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    2016/01/01
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    Sample Type: Cell Lysates
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    PubMed
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    Zhang SR et al. Capilliposide from Lysimachia capillipes inhibits AKT activation and restores gefitinib sensitivity in human non-small cell lung cancer cells with acquired gefitinib resistance. Acta Pharmacol. Sin. 2017 Jan;38(1):100-109
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    2017/01/01
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    Sample Type: Cell Lysates
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    PubMed
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    Fotouhi Ghiam A et al. Long non-coding RNA urothelial carcinoma associated 1 (UCA1) mediates radiation response in prostate cancer. Oncotarget 2017 Jan;8(3):4668-4689
    Fotouhi Ghiam A et al
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    Sample Type: Cell Lysates
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    PubMed
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    Nadeau SA et al. Structural Determinants of the Gain-of-Function Phenotype of Human Leukemia-associated Mutant CBL Oncogene. J. Biol. Chem. 2017 Mar;292(9):3666-3682
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    Sample Type: Cell Lysates
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    PubMed
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    Bank坦 Z et al. Induction and Differentiation of IL-10-Producing Regulatory B Cells from Healthy Blood Donors and Rheumatoid Arthritis Patients. J. Immunol. 2017 Feb;198(4):1512-1520
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    Sample Type: Whole Cells
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    PubMed
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    Kuan II et al. EpEX/EpCAM and Oct4 or Klf4 alone are sufficient to generate induced pluripotent stem cells through STAT3 and HIF2&#x3B1;. Sci Rep 2017 Feb;7:41852
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    Sample Type: Cell Lysates
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    PubMed
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    Sample Type: Tissue Homogenates
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    PubMed
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    Buchanan PC et al. Ectodomain shedding of the cell adhesion molecule Nectin-4 in ovarian cancer is mediated by ADAM10 and ADAM17. J. Biol. Chem. 2017 Apr;292(15):6339-6351
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    Sample Type: cell supernates
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    PubMed
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    Kalyvianaki K et al. Antagonizing effects of membrane-acting androgens on the eicosanoid receptor OXER1 in prostate cancer. Sci Rep 2017 Mar;7:44418
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    2017/01/01
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    Sample Type: Cell Lysates
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    PubMed
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    Colomb F et al. Galectin-3 interacts with the cell-surface glycoprotein CD146 (MCAM, MUC18) and induces secretion of metastasis-promoting cytokines from vascular endothelial cells. J. Biol. Chem. 2017 May;292(20):8381-8389
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    Sample Type: Cell Lysates
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    PubMed
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    2017/01/01
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    Sample Type: Cell Lysates
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    PubMed
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