価格表

在庫・価格 : 2024年04月29日 05時24分 現在

商品名 商品コード メーカー 包装 価格 在庫 リスト
TACE, Human, Recombinant, Carrier-free <ADAM17>
データシート
930-ADB-010 RSDアールアンドディー システムス
R&D Systems, Inc.
10 μg ¥100,000
(未発注)
追加

在庫・価格 : 2024年04月29日 05時24分 現在

TACE, Human, Recombinant, Carrier-free <ADAM17>

  • 商品コード:930-ADB-010
  • メーカー:RSD
  • 包装:10μg
  • 価格: ¥100,000
  • 在庫:無(未発注)
使用文献
No. 文献情報 備考 参照
1 Tyler SJ et al. alpha- and beta-secretase: profound changes in Alzheimer&quot;s disease. Biochem. Biophys. Res. Commun. 2002 Dec;299(3):373-6
Tyler SJ et al
2002/01/01
PubMed
2 Liepinsh E et al. NMR structure of the netrin-like domain (NTR) of human type I procollagen C-proteinase enhancer defines structural consensus of NTR domains and assesses potential proteinase inhibitory activity and ligand binding. J. Biol. Chem. 2003 Jul
Liepinsh E et al
2003/01/01
Application: Activity Assay PubMed
3 von Tresckow B et al. Depletion of cellular cholesterol and lipid rafts increases shedding of CD30. J. Immunol. 2004 Apr;172(7):4324-31
von Tresckow B et al
2004/01/01
Application: Western Blot PubMed
4 Hinkle CL et al. Selective roles for tumor necrosis factor alpha-converting enzyme/ADAM17 in the shedding of the epidermal growth factor receptor ligand family: the juxtamembrane stalk determines cleavage efficiency. J. Biol. Chem. 2004 Jun;279(23):24179-
Hinkle CL et al
2004/01/01
Application: Enzyme Activity, Sample Type: recombinant protein PubMed
5 Thathiah A et al. MT1-MMP mediates MUC1 shedding independent of TACE/ADAM17. Biochem. J. 2004 Aug;382(Pt 1):363-73
Thathiah A et al
2004/01/01
Application: Enzyme Activity, Sample Type: Whole Cells PubMed
6 Famer D et al. Rosuvastatin reduces caspase-3 activity and up-regulates alpha-secretase in human neuroblastoma SH-SY5Y cells exposed to A beta. Neurosci. Lett. 2004 Nov;371(2-3):209-14
Famer D et al
2004/01/01
Application: Control PubMed
7 Nishi E et al. Nardilysin enhances ectodomain shedding of heparin-binding epidermal growth factor-like growth factor through activation of tumor necrosis factor-alpha-converting enzyme. J. Biol. Chem. 2006 Oct;281(41):31164-72
Nishi E et al
2006/01/01
Species: Human, Application: Bioassay, Sample type: Whole Cells PubMed
8 Tellier E et al. The shedding activity of ADAM17 is sequestered in lipid rafts. Exp. Cell Res. 2006 Dec;312(20):3969-80
Tellier E et al
2006/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
9 Eichenauer DA et al. ADAM10 inhibition of human CD30 shedding increases specificity of targeted immunotherapy in vitro. Cancer Res. 2007 Jan;67(1):332-8
Eichenauer DA et al
2007/01/01
Application: Bioassay, Sample Type: recombinant CD30 PubMed
10 Lemieux GA et al. The low affinity IgE receptor (CD23) is cleaved by the metalloproteinase ADAM10. J. Biol. Chem. 2007 May;282(20):14836-44
Lemieux GA et al
2007/01/01
Species: Human, Application: Enzyme Activity, Sample type: D10 affinity-matured variant of hVbeta2 PubMed
11 Lauer-Fields JL et al. Engineered sarafotoxins as tissue inhibitor of metalloproteinases-like matrix metalloproteinase inhibitors. J. Biol. Chem. 2007 Sep;282(37):26948-55
Lauer-Fields JL et al
2007/01/01
Species: Human, Application: Bioassay PubMed
12 Canault M et al. Microparticles of human atherosclerotic plaques enhance the shedding of the tumor necrosis factor-alpha converting enzyme/ADAM17 substrates, tumor necrosis factor and tumor necrosis factor receptor-1. Am. J. Pathol. 2007 Nov;171(5):1713-2
Canault M et al
2007/01/01
Species: Human, Application: Bioassay, Sample type: TACE peptide PubMed
13 Moss ML et al. The ADAM10 prodomain is a specific inhibitor of ADAM10 proteolytic activity and inhibits cellular shedding events. J. Biol. Chem. 2007 Dec;282(49):35712-21
Moss ML et al
2007/01/01
Species: Human, Application: Bioassay, Sample type: recombinant protein PubMed
14 Koenen RR et al. Regulated release and functional modulation of junctional adhesion molecule A by disintegrin metalloproteinases. Blood 2009 May;113(19):4799-809
Koenen RR et al
2009/01/01
Application: Bioassay,cleavage assay, Sample Type: Whole Cells,recombinant protein PubMed
15 Moreira-Tabaka H et al. Unlike for human monocytes after LPS activation, release of TNF-&#x3B1; by THP-1 cells is produced by a TACE catalytically different from constitutive TACE. PLoS ONE 2012;7(3):e34184
Moreira-Tabaka H et al
2012/01/01
Application: Enzyme Activity, Sample Type: Whole Cells PubMed
16 Gooz P et al. A disintegrin and metalloenzyme (ADAM) 17 activation is regulated by &#x3B1;5&#x3B2;1 integrin in kidney mesangial cells. PLoS ONE 2012;7(3):e33350
Gooz P et al
2012/01/01
Application: Binding Assay,Enzyme Activity, Sample Type: Fluorogenic Substrate,purified alpha5beta1 integrin PubMed
17 Hayes CD et al. Striking reduction of amyloid plaque burden in an Alzheimer&quot;s mouse model after chronic administration of carmustine. BMC Med 2013;11:81
Hayes CD et al
2013/01/01
Application: inhibition, Sample Type: Whole Cells PubMed
18 McDonald AJ et al. A new paradigm for enzymatic control of &#x3B1;-cleavage and &#x3B2;-cleavage of the prion protein. J. Biol. Chem. 2014 Jan;289(2):803-13
McDonald AJ et al
2014/01/01
Application: Enzyme Activity, Sample Type: Cell Lysate PubMed
19 Lajoie L et al. ADAM17-mediated shedding of Fc&#x3B3;RIIIA on human NK cells: identification of the cleavage site and relationship with activation. J. Immunol. 2014 Jan;192(2):741-51
Lajoie L et al
2014/01/01
Application: Bioassay, Sample Type: recombinant proteins PubMed
20 Schlomann U et al. ADAM8 as a drug target in pancreatic cancer. Nat Commun 2015;6:6175
Schlomann U et al
2015/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
21 Lee EJ et al. Matrix metalloproteinase-8 plays a pivotal role in neuroinflammation by modulating TNF-&#x3B1; activation. J. Immunol. 2014 Sep;193(5):2384-93
Lee EJ et al
2014/01/01
Application: Enzymatic Activity, Sample Type: Proteins PubMed
22 Fresco VM et al. Fibulin-1 Binds to Fibroblast Growth Factor 8 with High Affinity: EFFECTS ON EMBRYO SURVIVAL. J. Biol. Chem. 2016 Sep;291(36):18730-9
Fresco VM et al
2016/01/01
Application: Bioassay, Sample Type: Purified protein PubMed
23 Capone C et al. Mechanistic insights into a TIMP3-sensitive pathway constitutively engaged in the regulation of cerebral hemodynamics. Elife 2016 Aug;5
Capone C et al
2016/01/01
Application: In Vivo, Sample Type: In Vivo PubMed
24 Bolino A et al. Niacin-mediated Tace activation ameliorates CMT neuropathies with focal hypermyelination. EMBO Mol Med 2016 12;8(12):1438-1454
Bolino A et al
2016/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
  • No.: 1
  • 文献情報:
    Tyler SJ et al. alpha- and beta-secretase: profound changes in Alzheimer&quot;s disease. Biochem. Biophys. Res. Commun. 2002 Dec;299(3):373-6
    Tyler SJ et al
    2002/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 2
  • 文献情報:
    Liepinsh E et al. NMR structure of the netrin-like domain (NTR) of human type I procollagen C-proteinase enhancer defines structural consensus of NTR domains and assesses potential proteinase inhibitory activity and ligand binding. J. Biol. Chem. 2003 Jul
    Liepinsh E et al
    2003/01/01
  • 備考:
    Application: Activity Assay
  • 参照:
    PubMed
  • No.: 3
  • 文献情報:
    von Tresckow B et al. Depletion of cellular cholesterol and lipid rafts increases shedding of CD30. J. Immunol. 2004 Apr;172(7):4324-31
    von Tresckow B et al
    2004/01/01
  • 備考:
    Application: Western Blot
  • 参照:
    PubMed
  • No.: 4
  • 文献情報:
    Hinkle CL et al. Selective roles for tumor necrosis factor alpha-converting enzyme/ADAM17 in the shedding of the epidermal growth factor receptor ligand family: the juxtamembrane stalk determines cleavage efficiency. J. Biol. Chem. 2004 Jun;279(23):24179-
    Hinkle CL et al
    2004/01/01
  • 備考:
    Application: Enzyme Activity, Sample Type: recombinant protein
  • 参照:
    PubMed
  • No.: 5
  • 文献情報:
    Thathiah A et al. MT1-MMP mediates MUC1 shedding independent of TACE/ADAM17. Biochem. J. 2004 Aug;382(Pt 1):363-73
    Thathiah A et al
    2004/01/01
  • 備考:
    Application: Enzyme Activity, Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 6
  • 文献情報:
    Famer D et al. Rosuvastatin reduces caspase-3 activity and up-regulates alpha-secretase in human neuroblastoma SH-SY5Y cells exposed to A beta. Neurosci. Lett. 2004 Nov;371(2-3):209-14
    Famer D et al
    2004/01/01
  • 備考:
    Application: Control
  • 参照:
    PubMed
  • No.: 7
  • 文献情報:
    Nishi E et al. Nardilysin enhances ectodomain shedding of heparin-binding epidermal growth factor-like growth factor through activation of tumor necrosis factor-alpha-converting enzyme. J. Biol. Chem. 2006 Oct;281(41):31164-72
    Nishi E et al
    2006/01/01
  • 備考:
    Species: Human, Application: Bioassay, Sample type: Whole Cells
  • 参照:
    PubMed
  • No.: 8
  • 文献情報:
    Tellier E et al. The shedding activity of ADAM17 is sequestered in lipid rafts. Exp. Cell Res. 2006 Dec;312(20):3969-80
    Tellier E et al
    2006/01/01
  • 備考:
    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 9
  • 文献情報:
    Eichenauer DA et al. ADAM10 inhibition of human CD30 shedding increases specificity of targeted immunotherapy in vitro. Cancer Res. 2007 Jan;67(1):332-8
    Eichenauer DA et al
    2007/01/01
  • 備考:
    Application: Bioassay, Sample Type: recombinant CD30
  • 参照:
    PubMed
  • No.: 10
  • 文献情報:
    Lemieux GA et al. The low affinity IgE receptor (CD23) is cleaved by the metalloproteinase ADAM10. J. Biol. Chem. 2007 May;282(20):14836-44
    Lemieux GA et al
    2007/01/01
  • 備考:
    Species: Human, Application: Enzyme Activity, Sample type: D10 affinity-matured variant of hVbeta2
  • 参照:
    PubMed
  • No.: 11
  • 文献情報:
    Lauer-Fields JL et al. Engineered sarafotoxins as tissue inhibitor of metalloproteinases-like matrix metalloproteinase inhibitors. J. Biol. Chem. 2007 Sep;282(37):26948-55
    Lauer-Fields JL et al
    2007/01/01
  • 備考:
    Species: Human, Application: Bioassay
  • 参照:
    PubMed
  • No.: 12
  • 文献情報:
    Canault M et al. Microparticles of human atherosclerotic plaques enhance the shedding of the tumor necrosis factor-alpha converting enzyme/ADAM17 substrates, tumor necrosis factor and tumor necrosis factor receptor-1. Am. J. Pathol. 2007 Nov;171(5):1713-2
    Canault M et al
    2007/01/01
  • 備考:
    Species: Human, Application: Bioassay, Sample type: TACE peptide
  • 参照:
    PubMed
  • No.: 13
  • 文献情報:
    Moss ML et al. The ADAM10 prodomain is a specific inhibitor of ADAM10 proteolytic activity and inhibits cellular shedding events. J. Biol. Chem. 2007 Dec;282(49):35712-21
    Moss ML et al
    2007/01/01
  • 備考:
    Species: Human, Application: Bioassay, Sample type: recombinant protein
  • 参照:
    PubMed
  • No.: 14
  • 文献情報:
    Koenen RR et al. Regulated release and functional modulation of junctional adhesion molecule A by disintegrin metalloproteinases. Blood 2009 May;113(19):4799-809
    Koenen RR et al
    2009/01/01
  • 備考:
    Application: Bioassay,cleavage assay, Sample Type: Whole Cells,recombinant protein
  • 参照:
    PubMed
  • No.: 15
  • 文献情報:
    Moreira-Tabaka H et al. Unlike for human monocytes after LPS activation, release of TNF-&#x3B1; by THP-1 cells is produced by a TACE catalytically different from constitutive TACE. PLoS ONE 2012;7(3):e34184
    Moreira-Tabaka H et al
    2012/01/01
  • 備考:
    Application: Enzyme Activity, Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 16
  • 文献情報:
    Gooz P et al. A disintegrin and metalloenzyme (ADAM) 17 activation is regulated by &#x3B1;5&#x3B2;1 integrin in kidney mesangial cells. PLoS ONE 2012;7(3):e33350
    Gooz P et al
    2012/01/01
  • 備考:
    Application: Binding Assay,Enzyme Activity, Sample Type: Fluorogenic Substrate,purified alpha5beta1 integrin
  • 参照:
    PubMed
  • No.: 17
  • 文献情報:
    Hayes CD et al. Striking reduction of amyloid plaque burden in an Alzheimer&quot;s mouse model after chronic administration of carmustine. BMC Med 2013;11:81
    Hayes CD et al
    2013/01/01
  • 備考:
    Application: inhibition, Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 18
  • 文献情報:
    McDonald AJ et al. A new paradigm for enzymatic control of &#x3B1;-cleavage and &#x3B2;-cleavage of the prion protein. J. Biol. Chem. 2014 Jan;289(2):803-13
    McDonald AJ et al
    2014/01/01
  • 備考:
    Application: Enzyme Activity, Sample Type: Cell Lysate
  • 参照:
    PubMed
  • No.: 19
  • 文献情報:
    Lajoie L et al. ADAM17-mediated shedding of Fc&#x3B3;RIIIA on human NK cells: identification of the cleavage site and relationship with activation. J. Immunol. 2014 Jan;192(2):741-51
    Lajoie L et al
    2014/01/01
  • 備考:
    Application: Bioassay, Sample Type: recombinant proteins
  • 参照:
    PubMed
  • No.: 20
  • 文献情報:
    Schlomann U et al. ADAM8 as a drug target in pancreatic cancer. Nat Commun 2015;6:6175
    Schlomann U et al
    2015/01/01
  • 備考:
    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 21
  • 文献情報:
    Lee EJ et al. Matrix metalloproteinase-8 plays a pivotal role in neuroinflammation by modulating TNF-&#x3B1; activation. J. Immunol. 2014 Sep;193(5):2384-93
    Lee EJ et al
    2014/01/01
  • 備考:
    Application: Enzymatic Activity, Sample Type: Proteins
  • 参照:
    PubMed
  • No.: 22
  • 文献情報:
    Fresco VM et al. Fibulin-1 Binds to Fibroblast Growth Factor 8 with High Affinity: EFFECTS ON EMBRYO SURVIVAL. J. Biol. Chem. 2016 Sep;291(36):18730-9
    Fresco VM et al
    2016/01/01
  • 備考:
    Application: Bioassay, Sample Type: Purified protein
  • 参照:
    PubMed
  • No.: 23
  • 文献情報:
    Capone C et al. Mechanistic insights into a TIMP3-sensitive pathway constitutively engaged in the regulation of cerebral hemodynamics. Elife 2016 Aug;5
    Capone C et al
    2016/01/01
  • 備考:
    Application: In Vivo, Sample Type: In Vivo
  • 参照:
    PubMed
  • No.: 24
  • 文献情報:
    Bolino A et al. Niacin-mediated Tace activation ameliorates CMT neuropathies with focal hypermyelination. EMBO Mol Med 2016 12;8(12):1438-1454
    Bolino A et al
    2016/01/01
  • 備考:
    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed