価格表

在庫・価格 : 2026年04月20日 06時04分 現在

商品名 商品コード メーカー 包装 価格 在庫 リスト
IL-23, Mouse, Recombinant
データシート
1887-ML-010 RSDアールアンドディー システムズ
R&D Systems, Inc.
10 μg 本製品は取扱中止になりました 追加

在庫・価格 : 2026年04月20日 06時04分 現在

IL-23, Mouse, Recombinant

  • 商品コード:1887-ML-010
  • メーカー:RSD
  • 包装:10μg
  • 本製品は取扱中止になりました
使用文献
No. 文献情報 備考 参照
1 Bettelli E et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006 May;441(7090):235-8
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2 Ivanov S et al. Functional relevance of the IL-23-IL-17 axis in lungs in vivo. Am. J. Respir. Cell Mol. Biol. 2007 Apr;36(4):442-51
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3 Wu Q et al. IL-23-dependent IL-17 production is essential in neutrophil recruitment and activity in mouse lung defense against respiratory Mycoplasma pneumoniae infection. Microbes Infect. 2007 Jan;9(1):78-86
Wu Q et al
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4 Nakano N et al. Involvement of mast cells in IL-12/23 p40 production is essential for survival from polymicrobial infections. Blood 2007 Jun;109(11):4846-55
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5 Laurence A et al. Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation. Immunity 2007 Mar;26(3):371-81
Laurence A et al
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6 Mathur AN et al. Stat3 and Stat4 direct development of IL-17-secreting Th cells. J. Immunol. 2007 Apr;178(8):4901-7
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7 Br端stle A et al. The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4. Nat. Immunol. 2007 Sep;8(9):958-66
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8 Zelante T et al. IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance. Eur. J. Immunol. 2007 Oct;37(10):2695-706
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9 Fitzgerald DC et al. Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells. Nat. Immunol. 2007 Dec;8(12):1372-9
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10 Smith E et al. IL-23 is required for neutrophil homeostasis in normal and neutrophilic mice. J. Immunol. 2007 Dec;179(12):8274-9
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Species: Mouse, Application: Bioassay, Sample type: In Vivo PubMed
11 Guo B et al. The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice. J. Clin. Invest. 2008 May;118(5):1680-90
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12 Yang XO et al. Regulation of inflammatory responses by IL-17F. J. Exp. Med. 2008 May;205(5):1063-75
Yang XO et al
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13 Shinohara ML et al. Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin. Immunity 2008 Jul;29(1):68-78
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14 Lo CK et al. Natural killer cell degeneration exacerbates experimental arthritis in mice via enhanced interleukin-17 production. Arthritis Rheum. 2008 Sep;58(9):2700-11
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15 McKinley L et al. TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice. J. Immunol. 2008 Sep;181(6):4089-97
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16 Hamada H et al. Tc17, a unique subset of CD8 T cells that can protect against lethal influenza challenge. J. Immunol. 2009 Mar;182(6):3469-81
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17 Xu J et al. Liver X receptor agonist regulation of Th17 lymphocyte function in autoimmunity. J. Leukoc. Biol. 2009 Aug;86(2):401-9
Xu J et al
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18 Yao C et al. Prostaglandin E2-EP4 signaling promotes immune inflammation through Th1 cell differentiation and Th17 cell expansion. Nat. Med. 2009 Jun;15(6):633-40
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19 Ito Y et al. Gamma/delta T cells are the predominant source of interleukin-17 in affected joints in collagen-induced arthritis, but not in rheumatoid arthritis. Arthritis Rheum. 2009 Aug;60(8):2294-303
Ito Y et al
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Application: Stimulation, Sample Type: Whole Cells PubMed
20 Meeks KD et al. IL-23 is required for protection against systemic infection with Listeria monocytogenes. J. Immunol. 2009 Dec;183(12):8026-34
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21 Cho JS et al. IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice. J. Clin. Invest. 2010 May;120(5):1762-73
Cho JS et al
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Application: Bioassay, Sample Type: Whole Cells PubMed
22 De Luca A et al. IL-22 defines a novel immune pathway of antifungal resistance. Mucosal Immunol 2010 Jul;3(4):361-73
De Luca A et al
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Application: Bioassay, Sample Type: Whole Cells PubMed
23 Jones GW et al. Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation. FASEB J. 2011 Jan;25(1):409-19
Jones GW et al
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Application: Bioassay, Sample Type: Whole Cells PubMed
24 Kayamuro H et al. Interleukin-1 family cytokines as mucosal vaccine adjuvants for induction of protective immunity against influenza virus. J. Virol. 2010 Dec;84(24):12703-12
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Application: In Vivo, Sample Type: In Vivo PubMed
25 DePaolo RW et al. Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens. Nature 2011 Mar;471(7337):220-4
DePaolo RW et al
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26 Sawa S et al. ROR?t+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota. Nat. Immunol. 2011 Apr;12(4):320-6
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Application: Bioassay,In Vivo, Sample Type: In Vivo,Whole Cells PubMed
27 Nakajima K et al. Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesions in a mouse model. J. Immunol. 2011 Apr;186(7):4481-9
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Application: In Vivo, Sample Type: Mouse PubMed
28 Ma Y et al. Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy. J. Exp. Med. 2011 Mar;208(3):491-503
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Application: Bioassay, Sample Type: Whole Cells PubMed
29 Breslow JM et al. Innate immune responses to systemic Acinetobacter baumannii infection in mice: neutrophils, but not interleukin-17, mediate host resistance. Infect. Immun. 2011 Aug;79(8):3317-27
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30 Fridman JS et al. Preclinical evaluation of local JAK1 and JAK2 inhibition in cutaneous inflammation. J. Invest. Dermatol. 2011 Sep;131(9):1838-44
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31 Monticelli LA et al. Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus. Nat. Immunol. 2011 Nov;12(11):1045-54
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32 Dubin PJ et al. Interleukin-23-mediated inflammation in Pseudomonas aeruginosa pulmonary infection. Infect. Immun. 2012 Jan;80(1):398-409
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33 Gessner MA et al. Dectin-1-dependent interleukin-22 contributes to early innate lung defense against Aspergillus fumigatus. Infect. Immun. 2012 Jan;80(1):410-7
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34 Alcaide P et al. Difference in Th1 and Th17 lymphocyte adhesion to endothelium. J. Immunol. 2012 Feb;188(3):1421-30
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35 Lemos HP et al. Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNgamma production. Proc. Natl. Acad. Sci. U.S.A. 2009 Apr;106(14):5954-9
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Application: ELISA Standard,In Vivo, Sample Type: In Vivo,N/A PubMed
36 Casey KA et al. Antigen-independent differentiation and maintenance of effector-like resident memory T cells in tissues. J. Immunol. 2012 May;188(10):4866-75
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37 Flanagan K et al. Laminin-411 is a vascular ligand for MCAM and facilitates TH17 cell entry into the CNS. PLoS ONE 2012;7(7):e40443
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38 Freeman BE et al. Regulation of innate CD8+ T-cell activation mediated by cytokines. Proc. Natl. Acad. Sci. U.S.A. 2012 Jun;109(25):9971-6
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39 Harrington LE et al. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat. Immunol. 2005 Nov;6(11):1123-32
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40 Simons DM et al. Autoreactive Th1 cells activate monocytes to support regional Th17 responses in inflammatory arthritis. J. Immunol. 2013 Apr;190(7):3134-41
Simons DM et al
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Application: In vitro, Sample Type: Cell culture PubMed
41 Liu H et al. ERK differentially regulates Th17- and Treg-cell development and contributes to the pathogenesis of colitis. Eur. J. Immunol. 2013 Jul;43(7):1716-26
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Application: cell culture, Sample Type: whole cells PubMed
42 Matsumoto A et al. IL-22-producing RORγt-dependent innate lymphoid cells play a novel protective role in murine acute hepatitis. PLoS ONE 2013;8(4):e62853
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43 Yanaba K et al. Regulatory B cells suppress imiquimod-induced, psoriasis-like skin inflammation. J. Leukoc. Biol. 2013 Oct;94(4):563-73
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44 Ishida H et al. IL-23 protection against Plasmodium berghei infection in mice is partially dependent on IL-17 from macrophages. Eur. J. Immunol. 2013 Oct;43(10):2696-706
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45 Mascanfroni ID et al. IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39. Nat. Immunol. 2013 Oct;14(10):1054-63
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46 Chen Y et al. CD49a promotes T-cell-mediated hepatitis by driving T helper 1 cytokine and interleukin-17 production. Immunology 2014 Mar;141(3):388-400
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47 Chen J et al. Posttranscriptional gene regulation of IL-17 by the RNA-binding protein HuR is required for initiation of experimental autoimmune encephalomyelitis. J. Immunol. 2013 Dec;191(11):5441-50
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48 Pennell LM et al. Immunoregulatory effects of interferon-β in suppression of Th17 cells. J. Interferon Cytokine Res. 2014 May;34(5):330-41
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49 Fisher Y et al. Th1 polarization of T cells injected into the cerebrospinal fluid induces brain immunosurveillance. J. Immunol. 2014 Jan;192(1):92-102
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50 Liu Y et al. Therapeutic efficacy of suppressing the Jak/STAT pathway in multiple models of experimental autoimmune encephalomyelitis. J. Immunol. 2014 Jan;192(1):59-72
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51 Ashino S et al. Janus kinase 1/3 signaling pathways are key initiators of TH2 differentiation and lung allergic responses. J. Allergy Clin. Immunol. 2014 Apr;133(4):1162-74
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52 Pierson ER et al. B cells promote induction of experimental autoimmune encephalomyelitis by facilitating reactivation of T cells in the central nervous system. J. Immunol. 2014 Feb;192(3):929-39
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53 Yang CY et al. Dual-specificity phosphatase 14 (DUSP14/MKP6) negatively regulates TCR signaling by inhibiting TAB1 activation. J. Immunol. 2014 Feb;192(4):1547-57
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54 Guo X et al. Induction of innate lymphoid cell-derived interleukin-22 by the transcription factor STAT3 mediates protection against intestinal infection. Immunity 2014 Jan;40(1):25-39
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55 Khattar M et al. Interleukin-21 is a critical regulator of CD4 and CD8 T cell survival during priming under Interleukin-2 deprivation conditions. PLoS ONE 2014;9(1):e85882
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56 Ikeda S et al. Excess IL-1 signaling enhances the development of Th17 cells by downregulating TGF-β-induced Foxp3 expression. J. Immunol. 2014 Feb;192(4):1449-58
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57 Zhou H et al. Differential IL-10 production by DCs determines the distinct adjuvant effects of LPS and PTX in EAE induction. Eur. J. Immunol. 2014 May;44(5):1352-62
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58 Wang Y et al. The transcription factors T-bet and Runx are required for the ontogeny of pathogenic interferon-γ-producing T helper 17 cells. Immunity 2014 Mar;40(3):355-66
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60 Zhu E et al. miR-20b suppresses Th17 differentiation and the pathogenesis of experimental autoimmune encephalomyelitis by targeting RORγt and STAT3. J. Immunol. 2014 Jun;192(12):5599-609
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61 Reynolds C et al. Elongated TCR alpha chain CDR3 favors an altered CD4 cytokine profile. BMC Biol. 2014;12:32
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62 Hou Y et al. The inhibitory effect of IFN-γ on protease HTRA1 expression in rheumatoid arthritis. J. Immunol. 2014 Jul;193(1):130-8
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65 Knowlden SA et al. Regulation of T cell motility in vitro and in vivo by LPA and LPA2. PLoS ONE 2014;9(7):e101655
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66 Schiering C et al. The alarmin IL-33 promotes regulatory T-cell function in the intestine. Nature 2014 Sep;513(7519):564-8
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67 Neumann C et al. Role of Blimp-1 in programing Th effector cells into IL-10 producers. J. Exp. Med. 2014 Aug;211(9):1807-19
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68 Haftmann C et al. miR-148a is upregulated by Twist1 and T-bet and promotes Th1-cell survival by regulating the proapoptotic gene Bim. Eur. J. Immunol. 2015 Apr;45(4):1192-205
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69 Abadier M et al. Cell surface levels of endothelial ICAM-1 influence the transcellular or paracellular T-cell diapedesis across the blood-brain barrier. Eur. J. Immunol. 2015 Apr;45(4):1043-58
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70 Harada M et al. Temporal expression of growth factors triggered by epiregulin regulates inflammation development. J. Immunol. 2015 Feb;194(3):1039-46
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71 Nelson MH et al. The inducible costimulator augments Tc17 cell responses to self and tumor tissue. J. Immunol. 2015 Feb;194(4):1737-47
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72 Mooster JL et al. Defective lymphoid organogenesis underlies the immune deficiency caused by a heterozygous S32I mutation in IκBα. J. Exp. Med. 2015 Feb;212(2):185-202
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73 Basu R et al. IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iTreg cell balance. Nat. Immunol. 2015 Mar;16(3):286-95
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74 Schwinge D et al. Testosterone suppresses hepatic inflammation by the downregulation of IL-17, CXCL-9, and CXCL-10 in a mouse model of experimental acute cholangitis. J. Immunol. 2015 Mar;194(6):2522-30
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75 Mu単oz M et al. Interleukin-22 induces interleukin-18 expression from epithelial cells during intestinal infection. Immunity 2015 Feb;42(2):321-31
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76 Okamura T et al. TGF-β3-expressing CD4+CD25(-)LAG3+ regulatory T cells control humoral immune responses. Nat Commun 2015;6:6329
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77 Kim YU et al. Regulation of autoimmune germinal center reactions in lupus-prone BXD2 mice by follicular helper T cells. PLoS ONE 2015;10(3):e0120294
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78 Klimatcheva E et al. CXCL13 antibody for the treatment of autoimmune disorders. BMC Immunol. 2015;16:6
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79 Guo X et al. Innate Lymphoid Cells Control Early Colonization Resistance against Intestinal Pathogens through ID2-Dependent Regulation of the Microbiota. Immunity 2015 Apr;42(4):731-43
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80 Yeste A et al. IL-21 induces IL-22 production in CD4+ T cells. Nat Commun 2014;5:3753
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81 Dunne A et al. A novel TLR2 agonist from Bordetella pertussis is a potent adjuvant that promotes protective immunity with an acellular pertussis vaccine. Mucosal Immunol 2015 May;8(3):607-17
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82 Chen J et al. Dysbiosis caused by vitamin D receptor deficiency confers colonization resistance to Citrobacter rodentium through modulation of innate lymphoid cells. Mucosal Immunol 2015 May;8(3):618-26
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83 Russi AE et al. Cutting edge: c-Kit signaling differentially regulates type 2 innate lymphoid cell accumulation and susceptibility to central nervous system demyelination in male and female SJL mice. J. Immunol. 2015 Jun;194(12):5609-13
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84 Chen M et al. An A2B Adenosine Receptor Agonist Promotes Th17 Autoimmune Responses in Experimental Autoimmune Uveitis (EAU) via Dendritic Cell Activation. PLoS ONE 2015;10(7):e0132348
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85 Bozoyan L et al. Interleukin-36γ is expressed by neutrophils and can activate microglia, but has no role in experimental autoimmune encephalomyelitis. J Neuroinflammation 2015;12:173
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86 Monin L et al. Immune requirements for protective Th17 recall responses to Mycobacterium tuberculosis challenge. Mucosal Immunol 2015 Sep;8(5):1099-109
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87 Lombes A et al. Adaptive Immune-like γ/δ T Lymphocytes Share Many Common Features with Their α/β T Cell Counterparts. J. Immunol. 2015 Aug;195(4):1449-58
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88 Doisne JM et al. Composition, Development, and Function of Uterine Innate Lymphoid Cells. J. Immunol. 2015 Oct;195(8):3937-45
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89 Vel叩zquez F et al. CD43 Functions as an E-Selectin Ligand for Th17 Cells In Vitro and Is Required for Rolling on the Vascular Endothelium and Th17 Cell Recruitment during Inflammation In Vivo. J. Immunol. 2016 Feb;196(3):1305-16
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90 Lee JK et al. RGS10 deficiency ameliorates the severity of disease in experimental autoimmune encephalomyelitis. J Neuroinflammation 2016;13:24
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91 de Andrade Pereira B et al. Tolerance of activated pathogenic CD4+ T cells by transcriptional targeting of dendritic cells. Gene Ther. 2015 May;22(5):382-90
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92 Pasi S et al. Toll/Interleukin-1 Receptor Domain Derived from TcpC (TIR-TcpC) Ameliorates Experimental Autoimmune Arthritis by Down-modulating Th17 Cell Response. J. Biol. Chem. 2016 Jun;291(23):12358-69
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93 O'Leary CE et al. Ndfip-mediated degradation of Jak1 tunes cytokine signalling to limit expansion of CD4+ effector T cells. Nat Commun 2016 Apr;7:11226
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94 Larabee CM et al. Myelin-specific Th17 cells induce severe relapsing optic neuritis with irreversible loss of retinal ganglion cells in C57BL/6 mice. Mol. Vis. 2016;22:332-41
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95 Verrier T et al. Phenotypic and Functional Plasticity of Murine Intestinal NKp46+ Group 3 Innate Lymphoid Cells. J. Immunol. 2016 Jun;196(11):4731-8
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96 Zhao R et al. Blockade of Extracellular ATP Effect by Oxidized ATP Effectively Mitigated Induced Mouse Experimental Autoimmune Uveitis (EAU). PLoS ONE 2016;11(5):e0155953
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97 Michel ML et al. SLAM-associated protein favors the development of iNKT2 over iNKT17 cells. Eur. J. Immunol. 2016 Sep;46(9):2162-74
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98 Way EE et al. Dose-Dependent Suppression of Cytokine production from T cells by a Novel Phosphoinositide 3-Kinase Delta Inhibitor. Sci Rep 2016 Jul;6:30384
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99 Ippagunta SK et al. Keratinocytes contribute intrinsically to psoriasis upon loss of Tnip1 function. Proc. Natl. Acad. Sci. U.S.A. 2016 Oct;113(41):E6162-E6171
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100 Xue X et al. Pharmacologic modulation of RORγt translates to efficacy in preclinical and translational models of psoriasis and inflammatory arthritis. Sci Rep 2016 Dec;6:37977
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Application: Bioassay,In Vivo, Sample Type: In Vivo,Whole Cells PubMed
101 Layman AAK et al. Ndfip1 restricts Th17 cell potency by limiting lineage stability and proinflammatory cytokine production. Sci Rep 2017 01;7:39649
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102 L辿cuyer MA et al. Dual role of ALCAM in neuroinflammation and blood-brain barrier homeostasis. Proc. Natl. Acad. Sci. U.S.A. 2017 Jan;114(4):E524-E533
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103 Hao Z et al. K48-linked KLF4 ubiquitination by E3 ligase Mule controls T-cell proliferation and cell cycle progression. Nat Commun 2017 Jan;8:14003
Hao Z et al
2017/01/01
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104 Franchi L et al. Inhibiting Oxidative Phosphorylation In Vivo Restrains Th17 Effector Responses and Ameliorates Murine Colitis. J. Immunol. 2017 Apr;198(7):2735-2746
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105 Downs-Canner S et al. Suppressive IL-17A(+)Foxp3(+) and ex-Th17 IL-17A(neg)Foxp3(+) Treg cells are a source of tumour-associated Treg cells. Nat Commun 2017 Mar;8:14649
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106 Zhu H et al. RIG-I antiviral signaling drives interleukin-23 production and psoriasis-like skin disease. EMBO Mol Med 2017 May;9(5):589-604
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