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在庫・価格 : 2025年04月26日 21時51分 現在

商品名 商品コード メーカー 包装 価格 在庫 リスト
Anti-IL-1β, Mouse, Goat-Poly
データシート※最新のデータシートでない場合があります
AF-401-NA RSDアールアンドディー システムズ
R&D Systems, Inc.
100 μg ¥105,000 1個 追加

在庫・価格 : 2025年04月26日 21時51分 現在

Anti-IL-1β, Mouse, Goat-Poly

  • 商品コード:AF-401-NA
  • メーカー:RSD
  • 包装:100μg
  • 価格: ¥105,000
  • 在庫:1個
使用文献
No. 文献情報 備考 参照
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Mariani TJ et al
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Species: Rat, Application: Neutralization, Sample type: Cell Supernates PubMed
2 Mehlhorn G et al. Induction of cytokines in glial cells surrounding cortical beta-amyloid plaques in transgenic Tg2576 mice with Alzheimer pathology. Int. J. Dev. Neurosci. ;18(4-5):423-31
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3 Banks WA et al. Intravenous human interleukin-1alpha impairs memory processing in mice: dependence on blood-brain barrier transport into posterior division of the septum. J. Pharmacol. Exp. Ther. 2001 Nov;299(2):536-41
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4 Srivastava KD et al. Crucial role of interleukin-1beta and nitric oxide synthase in silica-induced inflammation and apoptosis in mice. Am. J. Respir. Crit. Care Med. 2002 Feb;165(4):527-33
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Application: Neutralization, Sample Type: Whole Cells PubMed
5 Woo MS et al. Differential regulation of inducible nitric oxide synthase and cytokine gene expression by forskolin and dibutyryl-cAMP in lipopolysaccharide-stimulated murine BV2 microglial cells. Neurosci. Lett. 2004 Feb;356(3):187-90
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Application: Western Blot, Sample Type: Cell Lysates PubMed
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Species: Mouse, Application: Immunoprecipitation, Sample type: Whole Cells PubMed
14 Sutterwala FS et al. Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity 2006 Mar;24(3):317-27
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16 Cho ML et al. STAT3 and NF-kappaB signal pathway is required for IL-23-mediated IL-17 production in spontaneous arthritis animal model IL-1 receptor antagonist-deficient mice. J. Immunol. 2006 May;176(9):5652-61
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17 Nandakumar KS et al. Arthritis induced with cartilage-specific antibodiesis IL-4-dependent. Eur. J. Immunol. 2006 Jun;36(6):1608-18
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18 Ha HY et al. Inhibition of the TPA-induced cutaneous inflammation and hyperplasia by EC-SOD. Biochem. Biophys. Res. Commun. 2006 Sep;348(2):450-8
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Application: IHC Paraffin-embedded,Western Blot, Sample Type: Homogenized Tissue,Whole Tissue PubMed
19 Shchors K et al. The Myc-dependent angiogenic switch in tumors is mediated by interleukin 1beta. Genes Dev. 2006 Sep;20(18):2527-38
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Species: Mouse, Application: Neutralization, Sample type: Whole Tissue PubMed
20 Stock C et al. Lysophosphatidylcholine stimulates IL-1beta release from microglia via a P2X7 receptor-independent mechanism. J. Immunol. 2006 Dec;177(12):8560-8
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Application: Western Blot, Sample Type: Cell Lysates PubMed
21 Stashenko P et al. Th1 immune response promotes severe bone resorption caused by Porphyromonas gingivalis. Am. J. Pathol. 2007 Jan;170(1):203-13
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22 Bouchard C et al. G protein-coupled receptor 84, a microglia-associated protein expressed in neuroinflammatory conditions. Glia 2007 Jun;55(8):790-800
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Species: Mouse, Application: Neutralization, Sample type: Whole Cells PubMed
23 Karuppagounder SS et al. Changes in inflammatory processes associated with selective vulnerability following mild impairment of oxidative metabolism. Neurobiol. Dis. 2007 May;26(2):353-62
Karuppagounder SS et al
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Species: Mouse, Application: IHC Fresh, Sample type: Whole Tissue PubMed
24 Medeiros MM et al. Toll-like receptor 4 (TLR4)-dependent proinflammatory and immunomodulatory properties of the glycoinositolphospholipid (GIPL) from Trypanosoma cruzi. J. Leukoc. Biol. 2007 Sep;82(3):488-96
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Species: Mouse, Application: Neutralization, Sample type: In Vivo PubMed
25 Ogiso T et al. Granulocyte colony-stimulating factor impairs liver regeneration in mice through the up-regulation of interleukin-1beta. J. Hepatol. 2007 Dec;47(6):816-25
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Species: Mouse, Application: Neutralization, Sample type: In Vivo PubMed
26 Cantor J et al. Recruitment and activation of macrophages by pathogenic CD4 T cells in type 1 diabetes: evidence for involvement of CCR8 and CCL1. J. Immunol. 2007 Nov;179(9):5760-7
Cantor J et al
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Species: Mouse, Application: Flow Cytometry, Sample type: Whole Cells PubMed
27 Miller LS et al. Inflammasome-mediated production of IL-1beta is required for neutrophil recruitment against Staphylococcus aureus in vivo. J. Immunol. 2007 Nov;179(10):6933-42
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Species: Mouse, Application: Western Blot, Sample type: Homogenized Tissue PubMed
28 Masunaga Y et al. Expression profiles of cytokines and chemokines in murine MDR1a-/- colitis. Inflamm. Res. 2007 Nov;56(11):439-46
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Species: Mouse, Application: IHC Frozen, Sample type: Whole Tissue PubMed
29 Pozsgai G et al. Topical acetone treatment induces neurogenic oedema on the sensitized mouse ear: an in vivo study using transient receptor potential vanilloid 1 (TRPV1) receptor knockout mice. Inflamm. Res. 2007 Nov;56(11):459-67
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Species: Mouse, Application: Functional Assay, Sample type: In Vivo PubMed
30 Das S et al. Japanese Encephalitis Virus infection induces IL-18 and IL-1beta in microglia and astrocytes: correlation with in vitro cytokine responsiveness of glial cells and subsequent neuronal death. J. Neuroimmunol. 2008 Mar;195(1-2):60-72
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Species: Mouse, Application: IHC Frozen, Western Blot, Whole Tissue, Homogenized Tissue PubMed
31 Maelfait J et al. Stimulation of Toll-like receptor 3 and 4 induces interleukin-1beta maturation by caspase-8. J. Exp. Med. 2008 Sep;205(9):1967-73
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Application: Western Blot, Sample Type: Cell Lysates PubMed
32 Hyv辰rinen K et al. Chlamydial and periodontal pathogens induce hepatic inflammation and fatty acid imbalance in apolipoprotein E-deficient mice. Infect. Immun. 2009 Aug;77(8):3442-9
Hyv辰rinen K et al
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Application: IHC Paraffin-embedded, Sample Type: Whole Tissue PubMed
33 Babelova A et al. Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors. J. Biol. Chem. 2009 Sep;284(36):24035-48
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34 Martin U et al. Externalization of the leaderless cytokine IL-1F6 occurs in response to lipopolysaccharide/ATP activation of transduced bone marrow macrophages. J. Immunol. 2009 Sep;183(6):4021-30
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Application: Western Blot, Sample Type: Cell Lysates,Cell Supernates PubMed
35 Ghiringhelli F et al. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat. Med. 2009 Oct;15(10):1170-8
Ghiringhelli F et al
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Application: Neutralization, Sample Type: Whole Cells PubMed
36 Ohno T et al. Caspase-1, caspase-8, and calpain are dispensable for IL-33 release by macrophages. J. Immunol. 2009 Dec;183(12):7890-7
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37 Hu L et al. Crucial role of phospholipase Cepsilon in induction of local skin inflammatory reactions in the elicitation stage of allergic contact hypersensitivity. J. Immunol. 2010 Jan;184(2):993-1002
Hu L et al
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Application: IHC Unspecified, Sample Type: Whole Tissue PubMed
38 Chen YT et al. Interleukin-1 as a phenotypic immunomodulator in keratinizing squamous metaplasia of the ocular surface in Sjテδカgren's syndrome. Am. J. Pathol. 2010 Sep;177(3):1333-43
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39 Radwan M et al. Tyrosine kinase 2 controls IL-1beta production at the translational level. J. Immunol. 2010 Sep;185(6):3544-53
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40 McCoy AJ et al. Cytotoxins of the human pathogen Aeromonas hydrophila trigger, via the NLRP3 inflammasome, caspase-1 activation in macrophages. Eur. J. Immunol. 2010 Oct;40(10):2797-803
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41 Masters SL et al. Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1? in type 2 diabetes. Nat. Immunol. 2010 Oct;11(10):897-904
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42 Yoshida H et al. Interleukin-1beta mediates the extra-intestinal thrombosis associated with experimental colitis. Am. J. Pathol. 2010 Dec;177(6):2774-81
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43 Carmi Y et al. Microenvironment-derived IL-1 and IL-17 interact in the control of lung metastasis. J. Immunol. 2011 Mar;186(6):3462-71
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45 Rider P et al. IL-1α and IL-1β recruit different myeloid cells and promote different stages of sterile inflammation. J. Immunol. 2011 Nov;187(9):4835-43
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46 Kim D et al. Toll-like receptor 2 contributes to chemokine gene expression and macrophage infiltration in the dorsal root ganglia after peripheral nerve injury. Mol Pain 2011;7:74
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47 Gessner MA et al. Dectin-1-dependent interleukin-22 contributes to early innate lung defense against Aspergillus fumigatus. Infect. Immun. 2012 Jan;80(1):410-7
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49 Broz P et al. Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1. Nature 2012 Oct;490(7419):288-91
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50 Lee GS et al. The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP. Nature 2012 Dec;492(7427):123-7
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52 Carmi Y et al. The Role of IL-1β in the Early Tumor Cell-Induced Angiogenic Response. J. Immunol. 2013 Apr;190(7):3500-9
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53 Misawa T et al. Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome. Nat. Immunol. 2013 May;14(5):454-60
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54 El-Zaatari M et al. Gli1 deletion prevents Helicobacter-induced gastric metaplasia and expansion of myeloid cell subsets. PLoS ONE 2013;8(3):e58935
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56 Smedberg JR et al. Signaling pathways in murine dendritic cells that regulate the response to vesicular stomatitis virus vectors that express flagellin. J. Virol. 2014 Jan;88(2):777-85
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58 Tanaka S et al. Activation of microglia induces symptoms of Parkinson's disease in wild-type, but not in IL-1 knockout mice. J Neuroinflammation 2013;10:143
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60 Kanarek N et al. Critical role for IL-1β in DNA damage-induced mucositis. Proc. Natl. Acad. Sci. U.S.A. 2014 Feb;111(6):E702-11
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62 Gupta R et al. RNA and β-hemolysin of group B Streptococcus induce interleukin-1β (IL-1β) by activating NLRP3 inflammasomes in mouse macrophages. J. Biol. Chem. 2014 May;289(20):13701-5
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63 Rabolli V et al. Critical role of aquaporins in interleukin 1β (IL-1β)-induced inflammation. J. Biol. Chem. 2014 May;289(20):13937-47
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64 Meunier E et al. Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases. Nature 2014 May;509(7500):366-70
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65 Nieto-Torres JL et al. Severe acute respiratory syndrome coronavirus envelope protein ion channel activity promotes virus fitness and pathogenesis. PLoS Pathog. 2014 May;10(5):e1004077
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66 England H et al. Release of interleukin-1α or interleukin-1β depends on mechanism of cell death. J. Biol. Chem. 2014 Jun;289(23):15942-50
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67 Zhao C et al. Nuclear factor E2-related factor-2 (Nrf2) is required for NLRP3 and AIM2 inflammasome activation. J. Biol. Chem. 2014 Jun;289(24):17020-9
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68 Kajiwara Y et al. A critical role for human caspase-4 in endotoxin sensitivity. J. Immunol. 2014 Jul;193(1):335-43
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69 Asrat S et al. The frustrated host response to Legionella pneumophila is bypassed by MyD88-dependent translation of pro-inflammatory cytokines. PLoS Pathog. 2014 Jul;10(7):e1004229
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70 Ganesan S et al. Caspase-8 modulates dectin-1 and complement receptor 3-driven IL-1β production in response to β-glucans and the fungal pathogen, Candida albicans. J. Immunol. 2014 Sep;193(5):2519-30
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Application: Western Blot, Sample Type: cell cultures PubMed
71 Lim YM et al. Systemic autophagy insufficiency compromises adaptation to metabolic stress and facilitates progression from obesity to diabetes. Nat Commun 2014;5:4934
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Application: Western Blot, Sample Type: tissue lysates PubMed
72 Hari A et al. Activation of NLRP3 inflammasome by crystalline structures via cell surface contact. Sci Rep 2014;4:7281
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73 Segovia JA et al. Nedd8 regulates inflammasome-dependent caspase-1 activation. Mol. Cell. Biol. 2015 Feb;35(3):582-97
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74 Ahn H et al. Methylsulfonylmethane inhibits NLRP3 inflammasome activation. Cytokine 2015 Feb;71(2):223-31
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76 Moriwaki K et al. A RIPK3-caspase 8 complex mediates atypical pro-IL-1β processing. J. Immunol. 2015 Feb;194(4):1938-44
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77 Haldar S et al. Inflammation and pyroptosis mediate muscle expansion in an interleukin-1β (IL-1β)-dependent manner. J. Biol. Chem. 2015 Mar;290(10):6574-83
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78 Li B et al. IL-10 engages macrophages to shift Th17 cytokine dependency and pathogenicity during T-cell-mediated colitis. Nat Commun 2015;6:6131
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79 Finegan KG et al. ERK5 is a critical mediator of inflammation-driven cancer. Cancer Res. 2015 Feb;75(4):742-53
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80 Yang CS et al. Small heterodimer partner interacts with NLRP3 and negatively regulates activation of the NLRP3 inflammasome. Nat Commun 2015;6:6115
Yang CS et al
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Application: Western Blot, Sample Type: Cell Culture Supernates,Cell Lysates,Tissue Homogenates PubMed
81 Maier NK et al. The cyclopentenone prostaglandin 15d-PGJ2 inhibits the NLRP1 and NLRP3 inflammasomes. J. Immunol. 2015 Mar;194(6):2776-85
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Application: Western Blot, Sample Type: Cell Lysates PubMed
82 Lawlor KE et al. RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL. Nat Commun 2015;6:6282
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2015/01/01
Application: Western Blot, Sample Type: Cell Lysates,cell supernates PubMed
83 Chien CH et al. Local immunosuppressive microenvironment enhances migration of melanoma cells to lungs in DJ-1 knockout mice. PLoS ONE 2015;10(2):e0115827
Chien CH et al
2015/01/01
Application: In vivo, Sample Type: In Vivo PubMed
84 L旦rchner H et al. Myocardial healing requires Reg3β-dependent accumulation of macrophages in the ischemic heart. Nat. Med. 2015 Apr;21(4):353-62
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2015/01/01
Application: Western Blot, Sample Type: tissue lysates PubMed
85 Meunier E et al. Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida. Nat. Immunol. 2015 May;16(5):476-84
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86 Denes A et al. AIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3. Proc. Natl. Acad. Sci. U.S.A. 2015 Mar;112(13):4050-5
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Application: IHC Frozen, Sample Type: Whole Tissue PubMed
87 Sadeghi H et al. Caspase-1-independent IL-1 release mediates blister formation in autoantibody-induced tissue injury through modulation of endothelial adhesion molecules. J. Immunol. 2015 Apr;194(8):3656-63
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88 Sester DP et al. Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice. J. Immunol. 2015 Aug;195(3):1233-41
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89 Marty-Roix R et al. Identification of QS-21 as an Inflammasome-activating Molecular Component of Saponin Adjuvants. J. Biol. Chem. 2016 Jan;291(3):1123-36
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Application: Western Blot, Sample Type: Cell Culture Supernates,Cell Lysates PubMed
90 Wang X et al. The Tick Protein Sialostatin L2 Binds to Annexin A2 and Inhibits NLRC4-Mediated Inflammasome Activation. Infect. Immun. 2016 Jun;84(6):1796-805
Wang X et al
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Application: Western Blot, Sample Type: Cell Lysates PubMed
91 Park YH et al. Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS. Nat. Immunol. 2016 Aug;17(8):914-21
Park YH et al
2016/01/01
Application: Western Blot, Sample Type: Cell Culture Supernates,Cell Lysates PubMed
92 Meng N et al. Activation of NLRP3 inflammasomes in mouse hepatic stellate cells during Schistosoma J. infection. Oncotarget 2016 Jun;7(26):39316-39331
Meng N et al
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93 Stein R et al. Enzymatically Inactive Procaspase 1 stabilizes the ASC Pyroptosome and Supports Pyroptosome Spreading during Cell Division. J. Biol. Chem. 2016 Aug;291(35):18419-29
Stein R et al
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94 Braverman J et al. HIF-1α Is an Essential Mediator of IFN-γ-Dependent Immunity to Mycobacterium tuberculosis. J. Immunol. 2016 Aug;197(4):1287-97
Braverman J et al
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Application: Western Blot, Sample Type: Cell Lysates PubMed
95 Cader MZ et al. C13orf31 (FAMIN) is a central regulator of immunometabolic function. Nat. Immunol. 2016 Sep;17(9):1046-56
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96 Myles IA et al. CD8+ T cells produce a dialyzable antigen-specific activator of dendritic cells. J. Leukoc. Biol. 2017 Jan;101(1):307-320
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97 Lund AW et al. Lymphatic vessels regulate immune microenvironments in human and murine melanoma. J. Clin. Invest. 2016 Sep;126(9):3389-402
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98 Pereira M et al. CARD9 negatively regulates NLRP3-induced IL-1β production on Salmonella infection of macrophages. Nat Commun 2016 Sep;7:12874
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215 Li Z et al. Vaccine delivery alerts innate immune systems for more immunogenic vaccination. JCI Insight 2021 04;6(7)
Li Z et al
2021/01/01
Species: Mouse, Applications: Western Blot PubMed
216 Volchuk A et al. Indirect regulation of HMGB1 release by gasdermin D. Nat Commun 2020 09;11(1):4561
Volchuk A et al
2020/01/01
Species: Mouse, Applications: Western Blot PubMed
  • No.: 1
  • 文献情報:
    Mariani TJ et al. Fibroblast tropoelastin and alpha-smooth-muscle actin expression are repressed by particulate-activated macrophage-derived tumor necrosis factor-alpha in experimental silicosis. Am. J. Respir. Cell Mol. Biol. 1999 Aug;21(2):185-92
    Mariani TJ et al
    1999/01/01
  • 備考:
    Species: Rat, Application: Neutralization, Sample type: Cell Supernates
  • 参照:
    PubMed
  • No.: 2
  • 文献情報:
    Mehlhorn G et al. Induction of cytokines in glial cells surrounding cortical beta-amyloid plaques in transgenic Tg2576 mice with Alzheimer pathology. Int. J. Dev. Neurosci. ;18(4-5):423-31
    Mehlhorn G et al
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    Species: Mouse, Application: IHC Frozen, Sample type: Whole Tissue
  • 参照:
    PubMed
  • No.: 3
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    Banks WA et al. Intravenous human interleukin-1alpha impairs memory processing in mice: dependence on blood-brain barrier transport into posterior division of the septum. J. Pharmacol. Exp. Ther. 2001 Nov;299(2):536-41
    Banks WA et al
    2001/01/01
  • 備考:
    Application: Neutralization, Sample Type: In Vivo
  • 参照:
    PubMed
  • No.: 4
  • 文献情報:
    Srivastava KD et al. Crucial role of interleukin-1beta and nitric oxide synthase in silica-induced inflammation and apoptosis in mice. Am. J. Respir. Crit. Care Med. 2002 Feb;165(4):527-33
    Srivastava KD et al
    2002/01/01
  • 備考:
    Application: Neutralization, Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 5
  • 文献情報:
    Woo MS et al. Differential regulation of inducible nitric oxide synthase and cytokine gene expression by forskolin and dibutyryl-cAMP in lipopolysaccharide-stimulated murine BV2 microglial cells. Neurosci. Lett. 2004 Feb;356(3):187-90
    Woo MS et al
    2004/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 6
  • 文献情報:
    Lind MH et al. Tumor necrosis factor receptor 1-mediated signaling is required for skin cancer development induced by NF-kappaB inhibition. Proc. Natl. Acad. Sci. U.S.A. 2004 Apr;101(14):4972-7
    Lind MH et al
    2004/01/01
  • 備考:
    Application: IHC Paraffin-embedded, Sample Type: Whole Tissue
  • 参照:
    PubMed
  • No.: 7
  • 文献情報:
    Fan H et al. Cytokine dysregulation induced by apoptotic cells is a shared characteristic of macrophages from nonobese diabetic and systemic lupus erythematosus-prone mice. J. Immunol. 2004 Apr;172(8):4834-43
    Fan H et al
    2004/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 8
  • 文献情報:
    Kim HJ et al. Janus kinase 3 down-regulates lipopolysaccharide-induced IL-1 beta-converting enzyme activation by autocrine IL-10. J. Immunol. 2004 Apr;172(8):4948-55
    Kim HJ et al
    2004/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 9
  • 文献情報:
    Chandrasekar B et al. Beta-adrenergic stimulation induces interleukin-18 expression via beta2-AR, PI3K, Akt, IKK, and NF-kappaB. Biochem. Biophys. Res. Commun. 2004 Jun;319(2):304-11
    Chandrasekar B et al
    2004/01/01
  • 備考:
    Application: Neutralization, Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 10
  • 文献情報:
    Nurmi A et al. Pyrrolidine dithiocarbamate inhibits translocation of nuclear factor kappa-B in neurons and protects against brain ischaemia with a wide therapeutic time window. J. Neurochem. 2004 Nov;91(3):755-65
    Nurmi A et al
    2004/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 11
  • 文献情報:
    Chauhan NB et al. Propentofylline attenuates tau hyperphosphorylation in Alzheimer&#39;s Swedish mutant model Tg2576. Neuropharmacology 2005 Jan;48(1):93-104
    Chauhan NB et al
    2005/01/01
  • 備考:
    Application: IHC Fresh/Frozen, Sample Type: Whole Tissue
  • 参照:
    PubMed
  • No.: 12
  • 文献情報:
    Perrin FE et al. Involvement of monocyte chemoattractant protein-1, macrophage inflammatory protein-1alpha and interleukin-1beta in Wallerian degeneration. Brain 2005 Apr;128(Pt 4):854-66
    Perrin FE et al
    2005/01/01
  • 備考:
    Application: In vivo
  • 参照:
    PubMed
  • No.: 13
  • 文献情報:
    Mariathasan S et al. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 2006 Mar;440(7081):228-32
    Mariathasan S et al
    2006/01/01
  • 備考:
    Species: Mouse, Application: Immunoprecipitation, Sample type: Whole Cells
  • 参照:
    PubMed
  • No.: 14
  • 文献情報:
    Sutterwala FS et al. Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity 2006 Mar;24(3):317-27
    Sutterwala FS et al
    2006/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 15
  • 文献情報:
    Sarkar A et al. ASC directs NF-kappaB activation by regulating receptor interacting protein-2 (RIP2) caspase-1 interactions. J. Immunol. 2006 Apr;176(8):4979-86
    Sarkar A et al
    2006/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Supernates
  • 参照:
    PubMed
  • No.: 16
  • 文献情報:
    Cho ML et al. STAT3 and NF-kappaB signal pathway is required for IL-23-mediated IL-17 production in spontaneous arthritis animal model IL-1 receptor antagonist-deficient mice. J. Immunol. 2006 May;176(9):5652-61
    Cho ML et al
    2006/01/01
  • 備考:
    Species: Mouse, Application: IHC Paraffin-embedded, Sample type: Whole Tissue
  • 参照:
    PubMed
  • No.: 17
  • 文献情報:
    Nandakumar KS et al. Arthritis induced with cartilage-specific antibodiesis IL-4-dependent. Eur. J. Immunol. 2006 Jun;36(6):1608-18
    Nandakumar KS et al
    2006/01/01
  • 備考:
    Species: Mouse, Application: IHC Frozen, Sample type: Whole Tissue
  • 参照:
    PubMed
  • No.: 18
  • 文献情報:
    Ha HY et al. Inhibition of the TPA-induced cutaneous inflammation and hyperplasia by EC-SOD. Biochem. Biophys. Res. Commun. 2006 Sep;348(2):450-8
    Ha HY et al
    2006/01/01
  • 備考:
    Application: IHC Paraffin-embedded,Western Blot, Sample Type: Homogenized Tissue,Whole Tissue
  • 参照:
    PubMed
  • No.: 19
  • 文献情報:
    Shchors K et al. The Myc-dependent angiogenic switch in tumors is mediated by interleukin 1beta. Genes Dev. 2006 Sep;20(18):2527-38
    Shchors K et al
    2006/01/01
  • 備考:
    Species: Mouse, Application: Neutralization, Sample type: Whole Tissue
  • 参照:
    PubMed
  • No.: 20
  • 文献情報:
    Stock C et al. Lysophosphatidylcholine stimulates IL-1beta release from microglia via a P2X7 receptor-independent mechanism. J. Immunol. 2006 Dec;177(12):8560-8
    Stock C et al
    2006/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 21
  • 文献情報:
    Stashenko P et al. Th1 immune response promotes severe bone resorption caused by Porphyromonas gingivalis. Am. J. Pathol. 2007 Jan;170(1):203-13
    Stashenko P et al
    2007/01/01
  • 備考:
    Application: IHC Paraffin-embedded, Sample Type: Whole Tissue
  • 参照:
    PubMed
  • No.: 22
  • 文献情報:
    Bouchard C et al. G protein-coupled receptor 84, a microglia-associated protein expressed in neuroinflammatory conditions. Glia 2007 Jun;55(8):790-800
    Bouchard C et al
    2007/01/01
  • 備考:
    Species: Mouse, Application: Neutralization, Sample type: Whole Cells
  • 参照:
    PubMed
  • No.: 23
  • 文献情報:
    Karuppagounder SS et al. Changes in inflammatory processes associated with selective vulnerability following mild impairment of oxidative metabolism. Neurobiol. Dis. 2007 May;26(2):353-62
    Karuppagounder SS et al
    2007/01/01
  • 備考:
    Species: Mouse, Application: IHC Fresh, Sample type: Whole Tissue
  • 参照:
    PubMed
  • No.: 24
  • 文献情報:
    Medeiros MM et al. Toll-like receptor 4 (TLR4)-dependent proinflammatory and immunomodulatory properties of the glycoinositolphospholipid (GIPL) from Trypanosoma cruzi. J. Leukoc. Biol. 2007 Sep;82(3):488-96
    Medeiros MM et al
    2007/01/01
  • 備考:
    Species: Mouse, Application: Neutralization, Sample type: In Vivo
  • 参照:
    PubMed
  • No.: 25
  • 文献情報:
    Ogiso T et al. Granulocyte colony-stimulating factor impairs liver regeneration in mice through the up-regulation of interleukin-1beta. J. Hepatol. 2007 Dec;47(6):816-25
    Ogiso T et al
    2007/01/01
  • 備考:
    Species: Mouse, Application: Neutralization, Sample type: In Vivo
  • 参照:
    PubMed
  • No.: 26
  • 文献情報:
    Cantor J et al. Recruitment and activation of macrophages by pathogenic CD4 T cells in type 1 diabetes: evidence for involvement of CCR8 and CCL1. J. Immunol. 2007 Nov;179(9):5760-7
    Cantor J et al
    2007/01/01
  • 備考:
    Species: Mouse, Application: Flow Cytometry, Sample type: Whole Cells
  • 参照:
    PubMed
  • No.: 27
  • 文献情報:
    Miller LS et al. Inflammasome-mediated production of IL-1beta is required for neutrophil recruitment against Staphylococcus aureus in vivo. J. Immunol. 2007 Nov;179(10):6933-42
    Miller LS et al
    2007/01/01
  • 備考:
    Species: Mouse, Application: Western Blot, Sample type: Homogenized Tissue
  • 参照:
    PubMed
  • No.: 28
  • 文献情報:
    Masunaga Y et al. Expression profiles of cytokines and chemokines in murine MDR1a-/- colitis. Inflamm. Res. 2007 Nov;56(11):439-46
    Masunaga Y et al
    2007/01/01
  • 備考:
    Species: Mouse, Application: IHC Frozen, Sample type: Whole Tissue
  • 参照:
    PubMed
  • No.: 29
  • 文献情報:
    Pozsgai G et al. Topical acetone treatment induces neurogenic oedema on the sensitized mouse ear: an in vivo study using transient receptor potential vanilloid 1 (TRPV1) receptor knockout mice. Inflamm. Res. 2007 Nov;56(11):459-67
    Pozsgai G et al
    2007/01/01
  • 備考:
    Species: Mouse, Application: Functional Assay, Sample type: In Vivo
  • 参照:
    PubMed
  • No.: 30
  • 文献情報:
    Das S et al. Japanese Encephalitis Virus infection induces IL-18 and IL-1beta in microglia and astrocytes: correlation with in vitro cytokine responsiveness of glial cells and subsequent neuronal death. J. Neuroimmunol. 2008 Mar;195(1-2):60-72
    Das S et al
    2008/01/01
  • 備考:
    Species: Mouse, Application: IHC Frozen, Western Blot, Whole Tissue, Homogenized Tissue
  • 参照:
    PubMed
  • No.: 31
  • 文献情報:
    Maelfait J et al. Stimulation of Toll-like receptor 3 and 4 induces interleukin-1beta maturation by caspase-8. J. Exp. Med. 2008 Sep;205(9):1967-73
    Maelfait J et al
    2008/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 32
  • 文献情報:
    Hyv辰rinen K et al. Chlamydial and periodontal pathogens induce hepatic inflammation and fatty acid imbalance in apolipoprotein E-deficient mice. Infect. Immun. 2009 Aug;77(8):3442-9
    Hyv辰rinen K et al
    2009/01/01
  • 備考:
    Application: IHC Paraffin-embedded, Sample Type: Whole Tissue
  • 参照:
    PubMed
  • No.: 33
  • 文献情報:
    Babelova A et al. Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors. J. Biol. Chem. 2009 Sep;284(36):24035-48
    Babelova A et al
    2009/01/01
  • 備考:
    Application: IHC Paraffin-embedded, Sample Type: Whole Tissue
  • 参照:
    PubMed
  • No.: 34
  • 文献情報:
    Martin U et al. Externalization of the leaderless cytokine IL-1F6 occurs in response to lipopolysaccharide/ATP activation of transduced bone marrow macrophages. J. Immunol. 2009 Sep;183(6):4021-30
    Martin U et al
    2009/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates,Cell Supernates
  • 参照:
    PubMed
  • No.: 35
  • 文献情報:
    Ghiringhelli F et al. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat. Med. 2009 Oct;15(10):1170-8
    Ghiringhelli F et al
    2009/01/01
  • 備考:
    Application: Neutralization, Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 36
  • 文献情報:
    Ohno T et al. Caspase-1, caspase-8, and calpain are dispensable for IL-33 release by macrophages. J. Immunol. 2009 Dec;183(12):7890-7
    Ohno T et al
    2009/01/01
  • 備考:
    Application: MUSTag PCR assay, Sample Type: DNA
  • 参照:
    PubMed
  • No.: 37
  • 文献情報:
    Hu L et al. Crucial role of phospholipase Cepsilon in induction of local skin inflammatory reactions in the elicitation stage of allergic contact hypersensitivity. J. Immunol. 2010 Jan;184(2):993-1002
    Hu L et al
    2010/01/01
  • 備考:
    Application: IHC Unspecified, Sample Type: Whole Tissue
  • 参照:
    PubMed
  • No.: 38
  • 文献情報:
    Chen YT et al. Interleukin-1 as a phenotypic immunomodulator in keratinizing squamous metaplasia of the ocular surface in Sjテδカgren&#39;s syndrome. Am. J. Pathol. 2010 Sep;177(3):1333-43
    Chen YT et al
    2010/01/01
  • 備考:
    Application: IHC Paraffin-embedded, Sample Type: Whole Tissue
  • 参照:
    PubMed
  • No.: 39
  • 文献情報:
    Radwan M et al. Tyrosine kinase 2 controls IL-1beta production at the translational level. J. Immunol. 2010 Sep;185(6):3544-53
    Radwan M et al
    2010/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 40
  • 文献情報:
    McCoy AJ et al. Cytotoxins of the human pathogen Aeromonas hydrophila trigger, via the NLRP3 inflammasome, caspase-1 activation in macrophages. Eur. J. Immunol. 2010 Oct;40(10):2797-803
    McCoy AJ et al
    2010/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 41
  • 文献情報:
    Masters SL et al. Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1? in type 2 diabetes. Nat. Immunol. 2010 Oct;11(10):897-904
    Masters SL et al
    2010/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Supernates
  • 参照:
    PubMed
  • No.: 42
  • 文献情報:
    Yoshida H et al. Interleukin-1beta mediates the extra-intestinal thrombosis associated with experimental colitis. Am. J. Pathol. 2010 Dec;177(6):2774-81
    Yoshida H et al
    2010/01/01
  • 備考:
    Application: Neutralization, Sample Type: In Vivo
  • 参照:
    PubMed
  • No.: 43
  • 文献情報:
    Carmi Y et al. Microenvironment-derived IL-1 and IL-17 interact in the control of lung metastasis. J. Immunol. 2011 Mar;186(6):3462-71
    Carmi Y et al
    2011/01/01
  • 備考:
    Application: Neutralization, Sample Type: In Vivo
  • 参照:
    PubMed
  • No.: 44
  • 文献情報:
    Bergsbaken T et al. Coordinated host responses during pyroptosis: caspase-1-dependent lysosome exocytosis and inflammatory cytokine maturation. J. Immunol. 2011 Sep;187(5):2748-54
    Bergsbaken T et al
    2011/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Supernates
  • 参照:
    PubMed
  • No.: 45
  • 文献情報:
    Rider P et al. IL-1&#x3B1; and IL-1&#x3B2; recruit different myeloid cells and promote different stages of sterile inflammation. J. Immunol. 2011 Nov;187(9):4835-43
    Rider P et al
    2011/01/01
  • 備考:
    Application: ICC,IHC Frozen,Neutralization, Sample Type: In Vivo,Whole Cells,Whole Tissue
  • 参照:
    PubMed
  • No.: 46
  • 文献情報:
    Kim D et al. Toll-like receptor 2 contributes to chemokine gene expression and macrophage infiltration in the dorsal root ganglia after peripheral nerve injury. Mol Pain 2011;7:74
    Kim D et al
    2011/01/01
  • 備考:
    Application: ICC, Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 47
  • 文献情報:
    Gessner MA et al. Dectin-1-dependent interleukin-22 contributes to early innate lung defense against Aspergillus fumigatus. Infect. Immun. 2012 Jan;80(1):410-7
    Gessner MA et al
    2012/01/01
  • 備考:
    Application: Neutralization, Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 48
  • 文献情報:
    Fisher DT et al. IL-6 trans-signaling licenses mouse and human tumor microvascular gateways for trafficking of cytotoxic T cells. J. Clin. Invest. 2011 Oct;121(10):3846-59
    Fisher DT et al
    2011/01/01
  • 備考:
    Application: In vivo, Sample Type: In Vivo
  • 参照:
    PubMed
  • No.: 49
  • 文献情報:
    Broz P et al. Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1. Nature 2012 Oct;490(7419):288-91
    Broz P et al
    2012/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Culture Supernates
  • 参照:
    PubMed
  • No.: 50
  • 文献情報:
    Lee GS et al. The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP. Nature 2012 Dec;492(7427):123-7
    Lee GS et al
    2012/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Culture Supernates,Cell Lysates
  • 参照:
    PubMed
  • No.: 51
  • 文献情報:
    He Y et al. The protein kinase PKR is critical for LPS-induced iNOS production but dispensable for inflammasome activation in macrophages. Eur. J. Immunol. 2013 May;43(5):1147-52
    He Y et al
    2013/01/01
  • 備考:
    Application: Not Specified, Sample Type: not specified
  • 参照:
    PubMed
  • No.: 52
  • 文献情報:
    Carmi Y et al. The Role of IL-1&#x3B2; in the Early Tumor Cell-Induced Angiogenic Response. J. Immunol. 2013 Apr;190(7):3500-9
    Carmi Y et al
    2013/01/01
  • 備考:
    Application: In Vivo, Sample Type: In Vivo
  • 参照:
    PubMed
  • No.: 53
  • 文献情報:
    Misawa T et al. Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome. Nat. Immunol. 2013 May;14(5):454-60
    Misawa T et al
    2013/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 54
  • 文献情報:
    El-Zaatari M et al. Gli1 deletion prevents Helicobacter-induced gastric metaplasia and expansion of myeloid cell subsets. PLoS ONE 2013;8(3):e58935
    El-Zaatari M et al
    2013/01/01
  • 備考:
    Application: IHC Fluorescence, Sample Type: Whole Tissue
  • 参照:
    PubMed
  • No.: 55
  • 文献情報:
    Li B et al. Wingless-type mammary tumor virus integration site family, member 5A (Wnt5a) regulates human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein 120 (gp120)-induced expression of pro-inflammatory cytokines via the Ca2+/calmodulin-depen
    Li B et al
    2013/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 56
  • 文献情報:
    Smedberg JR et al. Signaling pathways in murine dendritic cells that regulate the response to vesicular stomatitis virus vectors that express flagellin. J. Virol. 2014 Jan;88(2):777-85
    Smedberg JR et al
    2014/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 57
  • 文献情報:
    He Y et al. 3,4-methylenedioxy-&#x3B2;-nitrostyrene inhibits NLRP3 inflammasome activation by blocking assembly of the inflammasome. J. Biol. Chem. 2014 Jan;289(2):1142-50
    He Y et al
    2014/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Extracts,Cell culture supernatant
  • 参照:
    PubMed
  • No.: 58
  • 文献情報:
    Tanaka S et al. Activation of microglia induces symptoms of Parkinson&#39;s disease in wild-type, but not in IL-1 knockout mice. J Neuroinflammation 2013;10:143
    Tanaka S et al
    2013/01/01
  • 備考:
    Application: IHC Frozen, Sample Type: tissue
  • 参照:
    PubMed
  • No.: 59
  • 文献情報:
    Maier NK et al. Arsenic trioxide and other arsenical compounds inhibit the NLRP1, NLRP3, and NAIP5/NLRC4 inflammasomes. J. Immunol. 2014 Jan;192(2):763-70
    Maier NK et al
    2014/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 60
  • 文献情報:
    Kanarek N et al. Critical role for IL-1&#x3B2; in DNA damage-induced mucositis. Proc. Natl. Acad. Sci. U.S.A. 2014 Feb;111(6):E702-11
    Kanarek N et al
    2014/01/01
  • 備考:
    Application: IHC Paraffin-embedded, Sample Type: Whole Tissue
  • 参照:
    PubMed
  • No.: 61
  • 文献情報:
    Xia M et al. Endothelial NLRP3 inflammasome activation and enhanced neointima formation in mice by adipokine visfatin. Am. J. Pathol. 2014 May;184(5):1617-28
    Xia M et al
    2014/01/01
  • 備考:
    Application: IHC, Sample Type: Whole Tissue
  • 参照:
    PubMed
  • No.: 62
  • 文献情報:
    Gupta R et al. RNA and &#x3B2;-hemolysin of group B Streptococcus induce interleukin-1&#x3B2; (IL-1&#x3B2;) by activating NLRP3 inflammasomes in mouse macrophages. J. Biol. Chem. 2014 May;289(20):13701-5
    Gupta R et al
    2014/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates,cell supernates
  • 参照:
    PubMed
  • No.: 63
  • 文献情報:
    Rabolli V et al. Critical role of aquaporins in interleukin 1&#x3B2; (IL-1&#x3B2;)-induced inflammation. J. Biol. Chem. 2014 May;289(20):13937-47
    Rabolli V et al
    2014/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
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  • 文献情報:
    Meunier E et al. Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases. Nature 2014 May;509(7500):366-70
    Meunier E et al
    2014/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Extracts,Cell culture supernatant
  • 参照:
    PubMed
  • No.: 65
  • 文献情報:
    Nieto-Torres JL et al. Severe acute respiratory syndrome coronavirus envelope protein ion channel activity promotes virus fitness and pathogenesis. PLoS Pathog. 2014 May;10(5):e1004077
    Nieto-Torres JL et al
    2014/01/01
  • 備考:
    Application: Western Blot, Sample Type: Supernatant
  • 参照:
    PubMed
  • No.: 66
  • 文献情報:
    England H et al. Release of interleukin-1&#x3B1; or interleukin-1&#x3B2; depends on mechanism of cell death. J. Biol. Chem. 2014 Jun;289(23):15942-50
    England H et al
    2014/01/01
  • 備考:
    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 67
  • 文献情報:
    Zhao C et al. Nuclear factor E2-related factor-2 (Nrf2) is required for NLRP3 and AIM2 inflammasome activation. J. Biol. Chem. 2014 Jun;289(24):17020-9
    Zhao C et al
    2014/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 68
  • 文献情報:
    Kajiwara Y et al. A critical role for human caspase-4 in endotoxin sensitivity. J. Immunol. 2014 Jul;193(1):335-43
    Kajiwara Y et al
    2014/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysate,cell culture supernate
  • 参照:
    PubMed
  • No.: 69
  • 文献情報:
    Asrat S et al. The frustrated host response to Legionella pneumophila is bypassed by MyD88-dependent translation of pro-inflammatory cytokines. PLoS Pathog. 2014 Jul;10(7):e1004229
    Asrat S et al
    2014/01/01
  • 備考:
    Application: Western Blot, Sample Type: cell supernates
  • 参照:
    PubMed
  • No.: 70
  • 文献情報:
    Ganesan S et al. Caspase-8 modulates dectin-1 and complement receptor 3-driven IL-1&#x3B2; production in response to &#x3B2;-glucans and the fungal pathogen, Candida albicans. J. Immunol. 2014 Sep;193(5):2519-30
    Ganesan S et al
    2014/01/01
  • 備考:
    Application: Western Blot, Sample Type: cell cultures
  • 参照:
    PubMed
  • No.: 71
  • 文献情報:
    Lim YM et al. Systemic autophagy insufficiency compromises adaptation to metabolic stress and facilitates progression from obesity to diabetes. Nat Commun 2014;5:4934
    Lim YM et al
    2014/01/01
  • 備考:
    Application: Western Blot, Sample Type: tissue lysates
  • 参照:
    PubMed
  • No.: 72
  • 文献情報:
    Hari A et al. Activation of NLRP3 inflammasome by crystalline structures via cell surface contact. Sci Rep 2014;4:7281
    Hari A et al
    2014/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 73
  • 文献情報:
    Segovia JA et al. Nedd8 regulates inflammasome-dependent caspase-1 activation. Mol. Cell. Biol. 2015 Feb;35(3):582-97
    Segovia JA et al
    2015/01/01
  • 備考:
    Application: Immunoprecipitation,Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 74
  • 文献情報:
    Ahn H et al. Methylsulfonylmethane inhibits NLRP3 inflammasome activation. Cytokine 2015 Feb;71(2):223-31
    Ahn H et al
    2015/01/01
  • 備考:
    Application: Western Blot, Sample Type: Total protein
  • 参照:
    PubMed
  • No.: 75
  • 文献情報:
    Sitaras N et al. Retinal neurons curb inflammation and enhance revascularization in ischemic retinopathies via proteinase-activated receptor-2. Am. J. Pathol. 2015 Feb;185(2):581-95
    Sitaras N et al
    2015/01/01
  • 備考:
    Application: Western Blot, Sample Type: tissue lysates
  • 参照:
    PubMed
  • No.: 76
  • 文献情報:
    Moriwaki K et al. A RIPK3-caspase 8 complex mediates atypical pro-IL-1&#x3B2; processing. J. Immunol. 2015 Feb;194(4):1938-44
    Moriwaki K et al
    2015/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 77
  • 文献情報:
    Haldar S et al. Inflammation and pyroptosis mediate muscle expansion in an interleukin-1&#x3B2; (IL-1&#x3B2;)-dependent manner. J. Biol. Chem. 2015 Mar;290(10):6574-83
    Haldar S et al
    2015/01/01
  • 備考:
    Application: Western Blot, Sample Type: tissue lysates
  • 参照:
    PubMed
  • No.: 78
  • 文献情報:
    Li B et al. IL-10 engages macrophages to shift Th17 cytokine dependency and pathogenicity during T-cell-mediated colitis. Nat Commun 2015;6:6131
    Li B et al
    2015/01/01
  • 備考:
    Application: IHC OCT-embedded,Western Blot, Sample Type: Whole Tissue,tissue lysates
  • 参照:
    PubMed
  • No.: 79
  • 文献情報:
    Finegan KG et al. ERK5 is a critical mediator of inflammation-driven cancer. Cancer Res. 2015 Feb;75(4):742-53
    Finegan KG et al
    2015/01/01
  • 備考:
    Application: IHC Paraffin-embedded,Western Blot, Sample Type: Protein Lysates,Whole Tissue
  • 参照:
    PubMed
  • No.: 80
  • 文献情報:
    Yang CS et al. Small heterodimer partner interacts with NLRP3 and negatively regulates activation of the NLRP3 inflammasome. Nat Commun 2015;6:6115
    Yang CS et al
    2015/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Culture Supernates,Cell Lysates,Tissue Homogenates
  • 参照:
    PubMed
  • No.: 81
  • 文献情報:
    Maier NK et al. The cyclopentenone prostaglandin 15d-PGJ2 inhibits the NLRP1 and NLRP3 inflammasomes. J. Immunol. 2015 Mar;194(6):2776-85
    Maier NK et al
    2015/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 82
  • 文献情報:
    Lawlor KE et al. RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL. Nat Commun 2015;6:6282
    Lawlor KE et al
    2015/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates,cell supernates
  • 参照:
    PubMed
  • No.: 83
  • 文献情報:
    Chien CH et al. Local immunosuppressive microenvironment enhances migration of melanoma cells to lungs in DJ-1 knockout mice. PLoS ONE 2015;10(2):e0115827
    Chien CH et al
    2015/01/01
  • 備考:
    Application: In vivo, Sample Type: In Vivo
  • 参照:
    PubMed
  • No.: 84
  • 文献情報:
    L旦rchner H et al. Myocardial healing requires Reg3&#x3B2;-dependent accumulation of macrophages in the ischemic heart. Nat. Med. 2015 Apr;21(4):353-62
    L旦rchner H et al
    2015/01/01
  • 備考:
    Application: Western Blot, Sample Type: tissue lysates
  • 参照:
    PubMed
  • No.: 85
  • 文献情報:
    Meunier E et al. Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida. Nat. Immunol. 2015 May;16(5):476-84
    Meunier E et al
    2015/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 86
  • 文献情報:
    Denes A et al. AIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3. Proc. Natl. Acad. Sci. U.S.A. 2015 Mar;112(13):4050-5
    Denes A et al
    2015/01/01
  • 備考:
    Application: IHC Frozen, Sample Type: Whole Tissue
  • 参照:
    PubMed
  • No.: 87
  • 文献情報:
    Sadeghi H et al. Caspase-1-independent IL-1 release mediates blister formation in autoantibody-induced tissue injury through modulation of endothelial adhesion molecules. J. Immunol. 2015 Apr;194(8):3656-63
    Sadeghi H et al
    2015/01/01
  • 備考:
    Application: Bioassay,Western Blot, Sample Type: Tissue Homogenates,Whole Tissue
  • 参照:
    PubMed
  • No.: 88
  • 文献情報:
    Sester DP et al. Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice. J. Immunol. 2015 Aug;195(3):1233-41
    Sester DP et al
    2015/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Culture Supernates
  • 参照:
    PubMed
  • No.: 89
  • 文献情報:
    Marty-Roix R et al. Identification of QS-21 as an Inflammasome-activating Molecular Component of Saponin Adjuvants. J. Biol. Chem. 2016 Jan;291(3):1123-36
    Marty-Roix R et al
    2016/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Culture Supernates,Cell Lysates
  • 参照:
    PubMed
  • No.: 90
  • 文献情報:
    Wang X et al. The Tick Protein Sialostatin L2 Binds to Annexin A2 and Inhibits NLRC4-Mediated Inflammasome Activation. Infect. Immun. 2016 Jun;84(6):1796-805
    Wang X et al
    2016/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 91
  • 文献情報:
    Park YH et al. Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS. Nat. Immunol. 2016 Aug;17(8):914-21
    Park YH et al
    2016/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Culture Supernates,Cell Lysates
  • 参照:
    PubMed
  • No.: 92
  • 文献情報:
    Meng N et al. Activation of NLRP3 inflammasomes in mouse hepatic stellate cells during Schistosoma J. infection. Oncotarget 2016 Jun;7(26):39316-39331
    Meng N et al
    2016/01/01
  • 備考:
    Application: IF,IHC - Paraffin embedded, Sample Type: Whole Tissue
  • 参照:
    PubMed
  • No.: 93
  • 文献情報:
    Stein R et al. Enzymatically Inactive Procaspase 1 stabilizes the ASC Pyroptosome and Supports Pyroptosome Spreading during Cell Division. J. Biol. Chem. 2016 Aug;291(35):18419-29
    Stein R et al
    2016/01/01
  • 備考:
    Application: Bead-based Immunoassay, Sample Type: Cell Culture Supernates
  • 参照:
    PubMed
  • No.: 94
  • 文献情報:
    Braverman J et al. HIF-1&#x3B1; Is an Essential Mediator of IFN-&#x3B3;-Dependent Immunity to Mycobacterium tuberculosis. J. Immunol. 2016 Aug;197(4):1287-97
    Braverman J et al
    2016/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 95
  • 文献情報:
    Cader MZ et al. C13orf31 (FAMIN) is a central regulator of immunometabolic function. Nat. Immunol. 2016 Sep;17(9):1046-56
    Cader MZ et al
    2016/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 96
  • 文献情報:
    Myles IA et al. CD8+ T cells produce a dialyzable antigen-specific activator of dendritic cells. J. Leukoc. Biol. 2017 Jan;101(1):307-320
    Myles IA et al
    2017/01/01
  • 備考:
    Application: Neutralization, Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 97
  • 文献情報:
    Lund AW et al. Lymphatic vessels regulate immune microenvironments in human and murine melanoma. J. Clin. Invest. 2016 Sep;126(9):3389-402
    Lund AW et al
    2016/01/01
  • 備考:
    Application: Western Blot, Sample Type: Tissue Homogenates
  • 参照:
    PubMed
  • No.: 98
  • 文献情報:
    Pereira M et al. CARD9 negatively regulates NLRP3-induced IL-1&#x3B2; production on Salmonella infection of macrophages. Nat Commun 2016 Sep;7:12874
    Pereira M et al
    2016/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 99
  • 文献情報:
    Mittal M et al. TNF&#x3B1;-stimulated gene-6 (TSG6) activates macrophage phenotype transition to prevent inflammatory lung injury. Proc. Natl. Acad. Sci. U.S.A. 2016 Dec;113(50):E8151-E8158
    Mittal M et al
    2016/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 100
  • 文献情報:
    Chavarr鱈a-Smith J et al. Functional and Evolutionary Analyses Identify Proteolysis as a General Mechanism for NLRP1 Inflammasome Activation. PLoS Pathog. 2016 Dec;12(12):e1006052
    Chavarr鱈a-Smith J et al
    2016/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 101
  • 文献情報:
    Haldar S et al. Histone deacetylase inhibitors mediate DNA damage repair in ameliorating hemorrhagic cystitis. Sci Rep 2016 Dec;6:39257
    Haldar S et al
    2016/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates,Tissue Homogenates
  • 参照:
    PubMed
  • No.: 102
  • 文献情報:
    Koh HJ et al. Toxoplasma gondii GRA7-Targeted ASC and PLD1 Promote Antibacterial Host Defense via PKC&#x3B1;. PLoS Pathog. 2017 Jan;13(1):e1006126
    Koh HJ et al
    2017/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 103
  • 文献情報:
    Tufanli O et al. Targeting IRE1 with small molecules counteracts progression of atherosclerosis. Proc. Natl. Acad. Sci. U.S.A. 2017 Feb;114(8):E1395-E1404
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    2017/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 104
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    Tsugita M et al. SR-B1 Is a Silica Receptor that Mediates Canonical Inflammasome Activation. Cell Rep 2017 Jan;18(5):1298-1311
    Tsugita M et al
    2017/01/01
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    Application: Western Blot, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 105
  • 文献情報:
    Domiciano TP et al. Quercetin Inhibits Inflammasome Activation by Interfering with ASC Oligomerization and Prevents Interleukin-1 Mediated Mouse Vasculitis. Sci Rep 2017 Feb;7:41539
    Domiciano TP et al
    2017/01/01
  • 備考:
    Application: Western Blot, Sample Type: Cell Lysis
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    PubMed
  • No.: 106
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    Moriwaki K et al. Distinct Kinase-Independent Role of RIPK3 in CD11c(+) Mononuclear Phagocytes in Cytokine-Induced Tissue Repair. Cell Rep 2017 Mar;18(10):2441-2451
    Moriwaki K et al
    2017/01/01
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    Application: Western Blot, Sample Type: Cell Lysates
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    PubMed
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  • 文献情報:
    McDonough EM et al. MTG16 is a tumor suppressor in colitis-associated carcinoma. JCI Insight 2017 Aug;2(16)
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    2017/01/01
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    Application: IHC paraffin embedded, Sample Type: Whole Tissue
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    PubMed
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    Neudecker V et al. Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome. J. Exp. Med. 2017 Jun;214(6):1737-1752
    Neudecker V et al
    2017/01/01
  • 備考:
    Species: Mouse, Applications: WB
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    PubMed
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    Choo MK et al. TLR sensing of bacterial spore-associated RNA triggers host immune responses with detrimental effects. J. Exp. Med. 2017 05;214(5):1297-1311
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    2017/01/01
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    Species: Mouse, Applications: WB
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    PubMed
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    Carroll RG et al. An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation. J. Biol. Chem. 2018 Apr;293(15):5509-5521
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    2018/01/01
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    Species: Mouse, Applications: WB
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    PubMed
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    Chu LH et al. The oxidized phospholipid oxPAPC protects from septic shock by targeting the non-canonical inflammasome in macrophages. Nat Commun 2018 03;9(1):996
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    2018/01/01
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    Species: Mouse, Applications: WB
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    PubMed
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    Ahn H et al. Lentinan from shiitake selectively attenuates AIM2 and non-canonical inflammasome activation while inducing pro-inflammatory cytokine production. Sci Rep 2017 May;7(1):1314
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    2017/01/01
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    Species: Mouse, Applications: WB
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    PubMed
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    Rivera JC et al. Tetrahydrobiopterin (BH4) deficiency is associated with augmented inflammation and microvascular degeneration in the retina. J Neuroinflammation 2017 Sep;14(1):181
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    2017/01/01
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    Species: Mouse, Applications: IHC
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    PubMed
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    Vince JE et al. The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1&#x3B2; Activation. Cell Rep 2018 Nov;25(9):2339-2353.e4
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    Monteleone M et al. Interleukin-1&#x3B2; Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion. Cell Rep 2018 Aug;24(6):1425-1433
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    Mathur A et al. A multicomponent toxin from Bacillus cereus incites inflammation and shapes host outcome via the NLRP3 inflammasome. Nat Microbiol 2019 02;4(2):362-374
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    Zhuang W et al. MCMV triggers ROS/NLRP3-associated inflammasome activation in the inner ear of mice and cultured spiral ganglion neurons, contributing to sensorineural hearing loss. Int. J. Mol. Med. 2018 Jun;41(6):3448-3456
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    Kasper L et al. The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes. Nat Commun 2018 10;9(1):4260
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    Erlich Z et al. Macrophages, rather than DCs, are responsible for inflammasome activity in the GM-CSF BMDC model. Nat. Immunol. 2019 04;20(4):397-406
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    Chen Y et al. NLRP3 Inflammasome Formation and Activation in Nonalcoholic Steatohepatitis: Therapeutic Target for Antimetabolic Syndrome Remedy FTZ. Oxid Med Cell Longev 2018;2018:2901871
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    Kim YK et al. Inhibitory Effect and Mechanism of <i>Arctium lappa</i> Extract <i>on NLRP3</i> Inflammasome Activation. Evid Based Complement Alternat Med 2018;2018:6346734
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    Gunaratna RT et al. Dynamic role of the codon 72 p53 single-nucleotide polymorphism in mammary tumorigenesis in a humanized mouse model. Oncogene 2019 05;38(18):3535-3550
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    Shimada A et al. Increased cytokine expression in the choroid plexus stroma and epithelium in response to endotoxin-induced systemic inflammation in mice. Toxicol Rep 2021;8:520-528
    Shimada A et al
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    Species: Mouse, Applications: IHC
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    PubMed
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    Kajino-Sakamoto R et al. Synthetic lethality between MyD88 loss and mutations in Wnt/&#x3B2;-catenin pathway in intestinal tumor epithelial cells. Oncogene 2021 01;40(2):408-420
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    Species: Mouse, Applications: In Vivo
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    PubMed
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    Mishima Y et al. Sex-dependent differences in the gut microbiota following chronic nasal inflammation in adult mice. Sci Rep 2021 02;11(1):4640
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    Species: Mouse, Applications: IHC
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    PubMed
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    Kim YH et al. Secretory autophagy machinery and vesicular trafficking are involved in HMGB1 secretion. Autophagy 2020 Oct;:1-18
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    Species: Mouse, Applications: Western Blot
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    PubMed
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    Donado CA et al. A Two-Cell Model for IL-1&#x3B2; Release Mediated by Death-Receptor Signaling. Cell Rep 2020 Apr;31(1):107466
    Donado CA et al
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    Species: Mouse, Applications: Western Blot
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    PubMed
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    Li Q et al. Inhibition of double-strand DNA-sensing cGAS ameliorates brain injury after ischemic stroke. EMBO Mol Med 2020 04;12(4):e11002
    Li Q et al
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    Species: Mouse, Applications: IHC
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    PubMed
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    Ahn H et al. Riboflavin, vitamin B2, attenuates NLRP3, NLRC4, AIM2, and non-canonical inflammasomes by the inhibition of caspase-1 activity. Sci Rep 2020 11;10(1):19091
    Ahn H et al
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    Species: Human, Applications: Western Blot
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    PubMed
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  • 文献情報:
    Lee MN et al. Luteolin inhibits NLRP3 inflammasome activation via blocking ASC oligomerization. J Nutr Biochem 2021 06;92:108614
    Lee MN et al
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    Species: Mouse, Applications: Western Blot
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    PubMed
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    Shi Y et al. NLRP3 inflammasome inhibitor INF39 attenuated NLRP3 assembly in macrophages. Int Immunopharmacol 2021 Mar;92:107358
    Shi Y et al
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    Species: Mouse, Applications: Western Blot
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    PubMed
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    Zhou B et al. Gasdermin E permits interleukin-1 beta release in distinct sublytic and pyroptotic phases. Cell Rep 2021 04;35(2):108998
    Zhou B et al
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    Species: Mouse, Applications: Western Blot
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    Wang Y et al. ELMO2 association with G<i>&#x3B1;</i>i2 regulates pancreatic cancer cell chemotaxis and metastasis. PeerJ 2020;8:e8910
    Wang Y et al
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    Species: Mouse, Applications: Western Blot
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    PubMed
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    Li Z et al. Vaccine delivery alerts innate immune systems for more immunogenic vaccination. JCI Insight 2021 04;6(7)
    Li Z et al
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    Species: Mouse, Applications: Western Blot
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    Volchuk A et al. Indirect regulation of HMGB1 release by gasdermin D. Nat Commun 2020 09;11(1):4561
    Volchuk A et al
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    Species: Mouse, Applications: Western Blot
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    PubMed