Myostatin, Mouse, Recombinant <GDF-8>

データシート

• 商品コード：788-G8-010
• メーカー：RSD
• 包装：10μg
• 価格： ¥89,000
• 在庫：2個

マイリストに追加 マイリストに追加済

• No.： 1
• 文献情報：
  R鱈os R et al. Differential response to exogenous and endogenous myostatin in myoblasts suggests that myostatin acts as an autocrine factor in vivo. Endocrinology 2004 Jun;145(6):2795-803
  R鱈os R et al
  2004/01/01
  
• 備考：
  Species: Human, Mouse, Rat, Application: Bioassay, Sample type: Whole Cells
• 参照：
  

• No.： 2
• 文献情報：
  Amthor H et al. Follistatin complexes Myostatin and antagonises Myostatin-mediated inhibition of myogenesis. Dev. Biol. 2004 Jun;270(1):19-30
  Amthor H et al
  2004/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Tissue
• 参照：
  

• No.： 3
• 文献情報：
  Wagner KR et al. Muscle regeneration in the prolonged absence of myostatin. Proc. Natl. Acad. Sci. U.S.A. 2005 Feb;102(7):2519-24
  Wagner KR et al
  2005/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 4
• 文献情報：
  Kollias HD et al. Smad7 promotes and enhances skeletal muscle differentiation. Mol. Cell. Biol. 2006 Aug;26(16):6248-60
  Kollias HD et al
  2006/01/01
  
• 備考：
  Species: Mouse, Application: Bioassay, Sample type: Whole Cells
• 参照：
  

• No.： 5
• 文献情報：
  Ohsawa Y et al. Muscular atrophy of caveolin-3-deficient mice is rescued by myostatin inhibition. J. Clin. Invest. 2006 Nov;116(11):2924-34
  Ohsawa Y et al
  2006/01/01
  
• 備考：
  Application: Media Supplement, Sample Type: Whole Cells
• 参照：
  

• No.： 6
• 文献情報：
  Miller TM et al. Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis. Proc. Natl. Acad. Sci. U.S.A. 2006 Dec;103(51):19546-51
  Miller TM et al
  2006/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 7
• 文献情報：
  Mukherjee A et al. FSTL3 deletion reveals roles for TGF-beta family ligands in glucose and fat homeostasis in adults. Proc. Natl. Acad. Sci. U.S.A. 2007 Jan;104(4):1348-53
  Mukherjee A et al
  2007/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 8
• 文献情報：
  Hamrick MW et al. Loss of myostatin (GDF8) function increases osteogenic differentiation of bone marrow-derived mesenchymal stem cells but the osteogenic effect is ablated with unloading. Bone 2007 Jun;40(6):1544-53
  Hamrick MW et al
  2007/01/01
  
• 備考：
  Species: Mouse, Application: Bioassay, Sample type: Whole Cells
• 参照：
  

• No.： 9
• 文献情報：
  Huang Z et al. Regulation of myostatin signaling by c-Jun N-terminal kinase in C2C12 cells. Cell. Signal. 2007 Nov;19(11):2286-95
  Huang Z et al
  2007/01/01
  
• 備考：
  Species: Mouse, Application: Bioassay, Sample type: Whole Cells
• 参照：
  

• No.： 10
• 文献情報：
  Sengle G et al. Targeting of bone morphogenetic protein growth factor complexes to fibrillin. J. Biol. Chem. 2008 May;283(20):13874-88
  Sengle G et al
  2008/01/01
  
• 備考：
  Species: Human, Application: Biacore binding study, complex formation, recombinant Fibrillin
• 参照：
  

• No.： 11
• 文献情報：
  Sengle G et al. A new model for growth factor activation: type II receptors compete with the prodomain for BMP-7. J. Mol. Biol. 2008 Sep;381(4):1025-39
  Sengle G et al
  2008/01/01
  
• 備考：
  Species: Human, Application: Biacore binding study, ELISA development, recombinant ActRIA, recombinant ActRIIA, recombinant ActRIIB, recombinant BMPRIA, recombinant BMPRIB, recombinant BMPRII
• 参照：
  

• No.： 12
• 文献情報：
  Wilkes JJ et al. Loss-of-function mutation in myostatin reduces tumor necrosis factor alpha production and protects liver against obesity-induced insulin resistance. Diabetes 2009 May;58(5):1133-43
  Wilkes JJ et al
  2009/01/01
  
• 備考：
  Application: In Vivo, Sample Type: In Vivo
• 参照：
  

• No.： 13
• 文献情報：
  Cash JN et al. The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding. EMBO J. 2009 Sep;28(17):2662-76
  Cash JN et al
  2009/01/01
  
• 備考：
  Application: Binding Assay, Sample Type: Whole Cells
• 参照：
  

• No.： 14
• 文献情報：
  Diel P et al. Analysis of the effects of androgens and training on myostatin propeptide and follistatin concentrations in blood and skeletal muscle using highly sensitive Immuno PCR. Mol. Cell. Endocrinol. 2010 Dec;330(1-2):1-9
  Diel P et al
  2010/01/01
  
• 備考：
  Application: ELISA Standard, Sample Type: N/A
• 参照：
  

• No.： 15
• 文献情報：
  Wilson TR et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature 2012 Jul;487(7408):505-9
  Wilson TR et al
  2012/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 16
• 文献情報：
  Sneddon JB et al. Self-renewal of embryonic-stem-cell-derived progenitors by organ-matched mesenchyme. Nature 2012 Nov;491(7426):765-8
  Sneddon JB et al
  2012/01/01
  
• 備考：
  Application: Cell Culture Substrate, Sample Type: whole cells
• 参照：
  

• No.： 17
• 文献情報：
  Rodgers BD et al. Myostatin stimulates, not inihibits, C2C12 myoblast proliferation. Endocrinology 2014 Mar;155(3):670-5
  Rodgers BD et al
  2014/01/01
  
• 備考：
  Application: Bioassay, Sample Type: whole cells
• 参照：
  

• No.： 18
• 文献情報：
  Yang Z et al. Screening with a novel cell-based assay for TAZ activators identifies a compound that enhances myogenesis in C2C12 cells and facilitates muscle repair in a muscle injury model. Mol. Cell. Biol. 2014 May;34(9):1607-21
  Yang Z et al
  2014/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 19
• 文献情報：
  Biesemann N et al. Myostatin regulates energy homeostasis in the heart and prevents heart failure. Circ. Res. 2014 Jul;115(2):296-310
  Biesemann N et al
  2014/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 20
• 文献情報：
  Relizani K et al. Blockade of ActRIIB signaling triggers muscle fatigability and metabolic myopathy. Mol. Ther. 2014 Aug;22(8):1423-33
  Relizani K et al
  2014/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 21
• 文献情報：
  Horbelt D et al. Small molecules dorsomorphin and LDN-193189 inhibit myostatin/GDF8 signaling and promote functional myoblast differentiation. J. Biol. Chem. 2015 Feb;290(6):3390-404
  Horbelt D et al
  2015/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 22
• 文献情報：
  Latres E et al. Myostatin blockade with a fully human monoclonal antibody induces muscle hypertrophy and reverses muscle atrophy in young and aged mice. Skelet Muscle 2015;5:34
  Latres E et al
  2015/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 23
• 文献情報：
  Seto DN et al. A Key Role for Leukemia Inhibitory Factor in C26 Cancer Cachexia. J. Biol. Chem. 2015 Aug;290(32):19976-86
  Seto DN et al
  2015/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 24
• 文献情報：
  Walker RG et al. Structural basis for potency differences between GDF8 and GDF11. BMC Biol. 2017 Mar;15(1):19
  Walker RG et al
  2017/01/01
  
• 備考：
  Application: Bioassay,In Vivo, Sample Type: In Vivo,Whole Cells
• 参照：
  

• No.： 25
• 文献情報：
  Hammers DW et al. Supraphysiological levels of GDF11 induce striated muscle atrophy. EMBO Mol Med 2017 Apr;9(4):531-544
  Hammers DW et al
  2017/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 26
• 文献情報：
  Lee SB et al. Maltose binding protein-fusion enhances the bioactivity of truncated forms of pig myostatin propeptide produced in E. coli. PLoS ONE 2017;12(4):e0174956
  Lee SB et al
  2017/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：