価格表

在庫・価格 : 2024年03月29日 16時20分 現在

商品名 商品コード メーカー 包装 価格 在庫 リスト
Wnt-3a, Mouse, Recombinant
データシート
1324-WN-002 RSDアールアンドディー システムス
R&D Systems, Inc.
2 μg ¥61,000
(未発注)
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在庫・価格 : 2024年03月29日 16時20分 現在

Wnt-3a, Mouse, Recombinant

  • 商品コード:1324-WN-002
  • メーカー:RSD
  • 包装:2μg
  • 価格: ¥61,000
  • 在庫:無(未発注)
使用文献
No. 文献情報 備考 参照
1 Liu BY et al. The transforming activity of Wnt effectors correlates with their ability to induce the accumulation of mammary progenitor cells. Proc. Natl. Acad. Sci. U.S.A. 2004 Mar;101(12):4158-63
Liu BY et al
2004/01/01
Species: Mouse, Application: Bioassay, Sample type: Whole Cells PubMed
2 Winkler DG et al. Sclerostin inhibition of Wnt-3a-induced C3H10T1/2 cell differentiation is indirect and mediated by bone morphogenetic proteins. J. Biol. Chem. 2005 Jan;280(4):2498-502
Winkler DG et al
2005/01/01
Species: Mouse, Application: Bioassay, Whole Cells PubMed
3 Shimizu T et al. Wnt signaling controls the timing of oligodendrocyte development in the spinal cord. Dev. Biol. 2005 Jun;282(2):397-410
Shimizu T et al
2005/01/01
Species: Mouse, Application: Bioassay, Sample type: Whole Cells PubMed
4 Lowry WE et al. Defining the impact of beta-catenin/Tcf transactivation on epithelial stem cells. Genes Dev. 2005 Jul;19(13):1596-611
Lowry WE et al
2005/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
5 Dravid G et al. Defining the role of Wnt/beta-catenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cells. Stem Cells ;23(10):1489-501
Dravid G et al
Species: Human, Application: Bioassay, Sample type: Whole Cells PubMed
6 Capurro MI et al. Glypican-3 promotes the growth of hepatocellular carcinoma by stimulating canonical Wnt signaling. Cancer Res. 2005 Jul;65(14):6245-54
Capurro MI et al
2005/01/01
Species: Human, Application: Binding Assay, Whole Cells PubMed
7 Hall CL et al. Prostate cancer cells promote osteoblastic bone metastases through Wnts. Cancer Res. 2005 Sep;65(17):7554-60
Hall CL et al
2005/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
8 Corti S et al. Multipotentiality, homing properties, and pyramidal neurogenesis of CNS-derived LeX(ssea-1)+/CXCR4+ stem cells. FASEB J. 2005 Nov;19(13):1860-2
Corti S et al
2005/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
9 Inoue T et al. Activation of canonical Wnt pathway promotes proliferation of retinal stem cells derived from adult mouse ciliary margin. Stem Cells 2006 Jan;24(1):95-104
Inoue T et al
2006/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
10 Yue Z et al. Wnt3a gradient converts radial to bilateral feather symmetry via topological arrangement of epithelia. Proc. Natl. Acad. Sci. U.S.A. 2006 Jan;103(4):951-5
Yue Z et al
2006/01/01
Application: In Vivo PubMed
11 Luo Y et al. SDF1alpha/CXCR4 signaling stimulates beta-catenin transcriptional activity in rat neural progenitors. Neurosci. Lett. 2006 May;398(3):291-5
Luo Y et al
2006/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
12 Ogawa K et al. Synergistic action of Wnt and LIF in maintaining pluripotency of mouse ES cells. Biochem. Biophys. Res. Commun. 2006 Apr;343(1):159-66
Ogawa K et al
2006/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
13 Lu J et al. Defined culture conditions of human embryonic stem cells. Proc. Natl. Acad. Sci. U.S.A. 2006 Apr;103(15):5688-93
Lu J et al
2006/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
14 Liu Y et al. A novel chemical-defined medium with bFGF and N2B27 supplements supports undifferentiated growth in human embryonic stem cells. Biochem. Biophys. Res. Commun. 2006 Jul;346(1):131-9
Liu Y et al
2006/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
15 Oloumi A et al. Modulation of Wnt3a-mediated nuclear beta-catenin accumulation and activation by integrin-linked kinase in mammalian cells. Oncogene 2006 Dec;25(59):7747-57
Oloumi A et al
2006/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
16 Tong M et al. Histone deacetylase inhibitors and transforming growth factor-beta induce 15-hydroxyprostaglandin dehydrogenase expression in human lung adenocarcinoma cells. Biochem. Pharmacol. 2006 Sep;72(6):701-9
Tong M et al
2006/01/01
Species: Human, Application: Bioassay, Whole Cells PubMed
17 Dejmek J et al. Wnt-5a/Ca2+-induced NFAT activity is counteracted by Wnt-5a/Yes-Cdc42-casein kinase 1alpha signaling in human mammary epithelial cells. Mol. Cell. Biol. 2006 Aug;26(16):6024-36
Dejmek J et al
2006/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
18 Nordstr旦m U et al. An early role for WNT signaling in specifying neural patterns of Cdx and Hox gene expression and motor neuron subtype identity. PLoS Biol. 2006 Jul;4(8):e252
Nordstr旦m U et al
2006/01/01
Species: Chicken, Application: Bioassay, Whole Tissue PubMed
19 Hasegawa K et al. A method for the selection of human embryonic stem cell sublines with high replating efficiency after single-cell dissociation. Stem Cells 2006 Dec;24(12):2649-60
Hasegawa K et al
2006/01/01
Species: Human, Application: Bioassay, Sample type: Whole Cells PubMed
20 Wang Y et al. Epm2a suppresses tumor growth in an immunocompromised host by inhibiting Wnt signaling. Cancer Cell 2006 Sep;10(3):179-90
Wang Y et al
2006/01/01
Species: Mouse, Application: Bioassay, Sample type: Whole Cells PubMed
21 Kim SE et al. The PI3 kinase-Akt pathway mediates Wnt3a-induced proliferation. Cell. Signal. 2007 Mar;19(3):511-8
Kim SE et al
2007/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
22 Sato A et al. Profilin is an effector for Daam1 in non-canonical Wnt signaling and is required for vertebrate gastrulation. Development 2006 Nov;133(21):4219-31
Sato A et al
2006/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
23 Bryja V et al. Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin. Cell. Signal. 2007 Mar;19(3):610-6
Bryja V et al
2007/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
24 Nygren MK et al. Wnt3A activates canonical Wnt signalling in acute lymphoblastic leukaemia (ALL) cells and inhibits the proliferation of B-ALL cell lines. Br. J. Haematol. 2007 Feb;136(3):400-13
Nygren MK et al
2007/01/01
Species: Human, Application: Bioassay, Sample type: Whole Cells PubMed
25 Kousteni S et al. Induction of osteoblast differentiation by selective activation of kinase-mediated actions of the estrogen receptor. Mol. Cell. Biol. 2007 Feb;27(4):1516-30
Kousteni S et al
2007/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
26 Abe K et al. NMDA-receptor activation induces calpain-mediated beta-catenin cleavages for triggering gene expression. Neuron 2007 Feb;53(3):387-97
Abe K et al
2007/01/01
Species: Mouse, Application: Bioassay, Sample type: Whole Cells PubMed
27 Miyabayashi T et al. Wnt/beta-catenin/CBP signaling maintains long-term murine embryonic stem cell pluripotency. Proc. Natl. Acad. Sci. U.S.A. 2007 Mar;104(13):5668-73
Miyabayashi T et al
2007/01/01
Species: Mouse, Application: Bioassay, Sample type: Whole Cells PubMed
28 Canning CA et al. Sustained interactive Wnt and FGF signaling is required to maintain isthmic identity. Dev. Biol. 2007 May;305(1):276-86
Canning CA et al
2007/01/01
Species: Chicken, Application: Bioassay, Sample type: Whole Tissue PubMed
29 Osakada F et al. Wnt signaling promotes regeneration in the retina of adult mammals. J. Neurosci. 2007 Apr;27(15):4210-9
Osakada F et al
2007/01/01
Species: Rat, Application: Bioassay, Sample type: Whole Tissue PubMed
30 Wawrzak D et al. Wnt3a binds to several sFRPs in the nanomolar range. Biochem. Biophys. Res. Commun. 2007 Jun;357(4):1119-23
Wawrzak D et al
2007/01/01
Species: Mouse, Application: Bioassay, Sample type: Whole Cells PubMed
31 Rydziel S et al. Nephroblastoma overexpressed (Nov) inhibits osteoblastogenesis and causes osteopenia. J. Biol. Chem. 2007 Jul;282(27):19762-72
Rydziel S et al
2007/01/01
Species: Mouse, Application: Bioassay, Sample type: GST and GST-Nov Fusion proteins, Whole Cells PubMed
32 Kwon C et al. Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors. Proc. Natl. Acad. Sci. U.S.A. 2007 Jun;104(26):10894-9
Kwon C et al
2007/01/01
Species: Mouse, Application: Bioassay, Sample type: Whole Cells PubMed
33 Giuliani N et al. Production of Wnt inhibitors by myeloma cells: potential effects on canonical Wnt pathway in the bone microenvironment. Cancer Res. 2007 Aug;67(16):7665-74
Giuliani N et al
2007/01/01
Species: Human, Application: Bioassay, Sample type: Whole Cells PubMed
34 Inoue T et al. Media conditioned by retinal pigment epithelial cells suppress the canonical Wnt pathway. Neurosci. Lett. 2007 Sep;424(3):190-3
Inoue T et al
2007/01/01
Species: Human, Application: Bioassay, Sample type: Whole Cells PubMed
35 Binnerts ME et al. R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6. Proc. Natl. Acad. Sci. U.S.A. 2007 Sep;104(37):14700-5
Binnerts ME et al
2007/01/01
Species: Human, Application: Bioassay, Sample type: Whole Cells PubMed
36 Zhang P et al. Short-term BMP-4 treatment initiates mesoderm induction in human embryonic stem cells. Blood 2008 Feb;111(4):1933-41
Zhang P et al
2008/01/01
Species: Human, Application: Bioassay, Whole Cells PubMed
37 Cho YM et al. Betacellulin and nicotinamide sustain PDX1 expression and induce pancreatic beta-cell differentiation in human embryonic stem cells. Biochem. Biophys. Res. Commun. 2008 Feb;366(1):129-34
Cho YM et al
2008/01/01
Species: Human, Application: Bioassay, Sample type: Whole Cells PubMed
38 Anderson BC et al. Myogenic growth factors can decrease extraocular muscle force generation: a potential biological approach to the treatment of strabismus. Invest. Ophthalmol. Vis. Sci. 2008 Jan;49(1):221-9
Anderson BC et al
2008/01/01
Species: Rabbit, Application: In Vivo PubMed
39 Elkabetz Y et al. Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage. Genes Dev. 2008 Jan;22(2):152-65
Elkabetz Y et al
2008/01/01
Species: Human, Application: Bioassay, Whole Cells PubMed
40 Endo Y et al. Wnt-3a and Dickkopf-1 stimulate neurite outgrowth in Ewing tumor cells via a Frizzled3- and c-Jun N-terminal kinase-dependent mechanism. Mol. Cell. Biol. 2008 Apr;28(7):2368-79
Endo Y et al
2008/01/01
Species: Human, Application: Bioassay, Whole Cells PubMed
41 Welters HJ et al. The protein tyrosine phosphatase-BL, modulates pancreatic beta-cell proliferation by interaction with the Wnt signalling pathway. J. Endocrinol. 2008 Jun;197(3):543-52
Welters HJ et al
2008/01/01
Species: Rat, Application: Bioassay, Whole Cells PubMed
42 Buglino JA et al. Hhat is a palmitoylacyltransferase with specificity for N-palmitoylation of Sonic Hedgehog. J. Biol. Chem. 2008 Aug;283(32):22076-88
Buglino JA et al
2008/01/01
Application: Bioassay PubMed
43 Dai J et al. Prostate cancer induces bone metastasis through Wnt-induced bone morphogenetic protein-dependent and independent mechanisms. Cancer Res. 2008 Jul;68(14):5785-94
Dai J et al
2008/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
44 Nakanishi M et al. Directed induction of anterior and posterior primitive streak by Wnt from embryonic stem cells cultured in a chemically defined serum-free medium. FASEB J. 2009 Jan;23(1):114-22
Nakanishi M et al
2009/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
45 Kennell JA et al. The microRNA miR-8 is a conserved negative regulator of Wnt signaling. Proc. Natl. Acad. Sci. U.S.A. 2008 Oct;105(40):15417-22
Kennell JA et al
2008/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
46 Verkaar F et al. Stably overexpressed human Frizzled-2 signals through the beta-catenin pathway and does not activate Ca2+-mobilization in Human Embryonic Kidney 293 cells. Cell. Signal. 2009 Jan;21(1):22-33
Verkaar F et al
2009/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
47 Wan M et al. Parathyroid hormone signaling through low-density lipoprotein-related protein 6. Genes Dev. 2008 Nov;22(21):2968-79
Wan M et al
2008/01/01
Application: In Vivo, Sample Type: In Vivo PubMed
48 Ford CE et al. Wnt-5a signaling restores tamoxifen sensitivity in estrogen receptor-negative breast cancer cells. Proc. Natl. Acad. Sci. U.S.A. 2009 Mar;106(10):3919-24
Ford CE et al
2009/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
49 Kim SE et al. H-Ras is degraded by Wnt/beta-catenin signaling via beta-TrCP-mediated polyubiquitylation. J. Cell. Sci. 2009 Mar;122(Pt 6):842-8
Kim SE et al
2009/01/01
Application: In Vivo, Sample Type: In Vivo PubMed
50 Liu CC et al. Cooperative folding and ligand-binding properties of LRP6 beta-propeller domains. J. Biol. Chem. 2009 May;284(22):15299-307
Liu CC et al
2009/01/01
Application: Bioassay,Receptor Binding Assay, Sample Type: N/A,Whole Cells PubMed
51 Borowiak M et al. Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells. Cell Stem Cell 2009 Apr;4(4):348-58
Borowiak M et al
2009/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
52 Shafer SL et al. Transcriptional regulation of SM22alpha by Wnt3a: convergence with TGFbeta(1)/Smad signaling at a novel regulatory element. J. Mol. Cell. Cardiol. 2009 May;46(5):621-35
Shafer SL et al
2009/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
53 Hansson M et al. A late requirement for Wnt and FGF signaling during activin-induced formation of foregut endoderm from mouse embryonic stem cells. Dev. Biol. 2009 Jun;330(2):286-304
Hansson M et al
2009/01/01
Application: differentiation, Sample Type: whole cell PubMed
54 Wexler EM et al. Endogenous Wnt signaling maintains neural progenitor cell potency. Stem Cells 2009 May;27(5):1130-41
Wexler EM et al
2009/01/01
Application: ELISA Standard, Sample Type: N/A PubMed
55 Gogolla N et al. Wnt signaling mediates experience-related regulation of synapse numbers and mossy fiber connectivities in the adult hippocampus. Neuron 2009 May;62(4):510-25
Gogolla N et al
2009/01/01
Application: In Vivo, Sample Type: In Vivo PubMed
56 Nejak-Bowen KN et al. Beta-catenin regulates vitamin C biosynthesis and cell survival in murine liver. J. Biol. Chem. 2009 Oct;284(41):28115-27
Nejak-Bowen KN et al
2009/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
57 Kr端tzfeldt J et al. Regulation of wingless-type MMTV integration site family (WNT) signalling in pancreatic islets from wild-type and obese mice. Diabetologia 2010 Jan;53(1):123-7
Kr端tzfeldt J et al
2010/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
58 Steele BM et al. Canonical Wnt signaling negatively regulates platelet function. Proc. Natl. Acad. Sci. U.S.A. 2009 Nov;106(47):19836-41
Steele BM et al
2009/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
59 Kawaguchi J et al. Isolation and propagation of enteric neural crest progenitor cells from mouse embryonic stem cells and embryos. Development 2010 Mar;137(5):693-704
Kawaguchi J et al
2010/01/01
Application: Media Supplement, Sample Type: Whole Cells PubMed
60 Gustafson B et al. Activation of canonical wingless-type MMTV integration site family (Wnt) signaling in mature adipocytes increases beta-catenin levels and leads to cell dedifferentiation and insulin resistance. J. Biol. Chem. 2010 Apr;285(18):14031-41
Gustafson B et al
2010/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
61 Trowbridge JJ et al. Wnt3a activates dormant c-Kit(-) bone marrow-derived cells with short-term multilineage hematopoietic reconstitution capacity. Stem Cells 2010 Aug;28(8):1379-89
Trowbridge JJ et al
2010/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
62 Roelandt P et al. Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to definitive endoderm, and finally hepatocyte-like cells. PLoS ONE 2010;5(8):e12101
Roelandt P et al
2010/01/01
Application: Expansion/Differentiation, Sample Type: Whole Cells PubMed
63 Gong Y et al. Wnt isoform-specific interactions with coreceptor specify inhibition or potentiation of signaling by LRP6 antibodies. PLoS ONE 2010;5(9):e12682
Gong Y et al
2010/01/01
Application: Binding Assay, Sample Type: recombinant LRP-6 PubMed
64 Del Debbio CB et al. Notch and Wnt signaling mediated rod photoreceptor regeneration by Mテδシller cells in adult mammalian retina. PLoS ONE 2010;5(8):e12425
Del Debbio CB et al
2010/01/01
Application: Bioassay, Sample Type: Retina Explant PubMed
65 Krause C et al. Distinct modes of inhibition by sclerostin on bone morphogenetic protein and Wnt signaling pathways. J. Biol. Chem. 2010 Dec;285(53):41614-26
Krause C et al
2010/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
66 Tsai SY et al. Single transcription factor reprogramming of hair follicle dermal papilla cells to induced pluripotent stem cells. Stem Cells 2011 Jun;29(6):964-71
Tsai SY et al
2011/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
67 Kelly OG et al. Cell-surface markers for the isolation of pancreatic cell types derived from human embryonic stem cells. Nat. Biotechnol. 2011 Aug;29(8):750-6
Kelly OG et al
2011/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
68 Lahar N et al. Intestinal subepithelial myofibroblasts support in vitro and in vivo growth of human small intestinal epithelium. PLoS ONE 2011;6(11):e26898
Lahar N et al
2011/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
69 Palsgaard J et al. Cross-talk between insulin and Wnt signaling in preadipocytes: role of Wnt co-receptor low density lipoprotein receptor-related protein-5 (LRP5). J. Biol. Chem. 2012 Apr;287(15):12016-26
Palsgaard J et al
2012/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
70 Goel S et al. Both LRP5 and LRP6 receptors are required to respond to physiological Wnt ligands in mammary epithelial cells and fibroblasts. J. Biol. Chem. 2012 May;287(20):16454-66
Goel S et al
2012/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
71 Walker TL et al. Prolactin stimulates precursor cells in the adult mouse hippocampus. PLoS ONE 2012;7(9):e44371
Walker TL et al
2012/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
72 Wang P et al. A molecular signature for purified definitive endoderm guides differentiation and isolation of endoderm from mouse and human embryonic stem cells. Stem Cells Dev. 2012 Aug;21(12):2273-87
Wang P et al
2012/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
73 Demidov ON et al. Role of Gadd45a in Wip1-dependent regulation of intestinal tumorigenesis. Cell Death Differ. 2012 Nov;19(11):1761-8
Demidov ON et al
2012/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
74 Tran H et al. Reversible modification of adenomatous polyposis coli (APC) with K63-linked polyubiquitin regulates the assembly and activity of the β-catenin destruction complex. J. Biol. Chem. 2012 Aug;287(34):28552-63
Tran H et al
2012/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
75 Tran TH et al. Heparan sulfate 6-O-endosulfatases (Sulfs) coordinate the Wnt signaling pathways to regulate myoblast fusion during skeletal muscle regeneration. J. Biol. Chem. 2012 Sep;287(39):32651-64
Tran TH et al
2012/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
76 Sneddon JB et al. Self-renewal of embryonic-stem-cell-derived progenitors by organ-matched mesenchyme. Nature 2012 Nov;491(7426):765-8
Sneddon JB et al
2012/01/01
Sample Type: whole cells PubMed
77 Tahamtani Y et al. Treatment of human embryonic stem cells with different combinations of priming and inducing factors toward definitive endoderm. Stem Cells Dev. 2013 May;22(9):1419-32
Tahamtani Y et al
2013/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
78 Halleskog C et al. Pertussis toxin-sensitive heterotrimeric G(αi/o) proteins mediate WNT/β-catenin and WNT/ERK1/2 signaling in mouse primary microglia stimulated with purified WNT-3A. Cell. Signal. 2013 Apr;25(4):822-8
Halleskog C et al
2013/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
79 Nakamura T et al. Fluid flow and interlinked feedback loops establish left-right asymmetric decay of Cerl2 mRNA. Nat Commun 2012;3:1322
Nakamura T et al
2012/01/01
Application: Bioassay, Sample Type: Whole Tissue PubMed
80 Mae S et al. Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells. Nat Commun 2013;4:1367
Mae S et al
2013/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
81 Li Y et al. Mesothelial cells give rise to hepatic stellate cells and myofibroblasts via mesothelial-mesenchymal transition in liver injury. Proc. Natl. Acad. Sci. U.S.A. 2013 Feb;110(6):2324-9
Li Y et al
2013/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
82 Gonz叩lez-Sancho JM et al. Functional consequences of Wnt-induced dishevelled 2 phosphorylation in canonical and noncanonical Wnt signaling. J. Biol. Chem. 2013 Mar;288(13):9428-37
Gonz叩lez-Sancho JM et al
2013/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
83 Huynh D et al. CSF-1 receptor-dependent colon development, homeostasis and inflammatory stress response. PLoS ONE 2013;8(2):e56951
Huynh D et al
2013/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
84 Busch AM et al. Evidence for tankyrases as antineoplastic targets in lung cancer. BMC Cancer 2013;13:211
Busch AM et al
2013/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
85 Zhou WJ et al. Induction of intestinal stem cells by R-spondin 1 and Slit2 augments chemoradioprotection. Nature 2013 Sep;501(7465):107-11
Zhou WJ et al
2013/01/01
Application: cell culture, Sample Type: whole cells PubMed
86 Yang J et al. BMP4 is required for the initial expression of MITF in melanocyte precursor differentiation from embryonic stem cells. Exp. Cell Res. 2014 Jan;320(1):54-61
Yang J et al
2014/01/01
Application: Bioassay, Sample Type: whole cells PubMed
87 Xavier CP et al. Secreted Frizzled-related protein potentiation versus inhibition of Wnt3a/β-catenin signaling. Cell. Signal. 2014 Jan;26(1):94-101
Xavier CP et al
2014/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
88 Salazar VS et al. Postnatal ablation of osteoblast Smad4 enhances proliferative responses to canonical Wnt signaling through interactions with β-catenin. J. Cell. Sci. 2013 Dec;126(Pt 24):5598-609
Salazar VS et al
2013/01/01
Application: differentiation, Sample Type: Whole Cells PubMed
89 Nishino J et al. A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties. Elife 2013;2:e00924
Nishino J et al
2013/01/01
Application: Bioassay, Sample Type: Cell culture PubMed
90 Stalvey MS et al. Osteoblast CFTR inactivation reduces differentiation and osteoprotegerin expression in a mouse model of cystic fibrosis-related bone disease. PLoS ONE 2013;8(11):e80098
Stalvey MS et al
2013/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
91 Boschert V et al. Mutational analysis of sclerostin shows importance of the flexible loop and the cystine-knot for Wnt-signaling inhibition. PLoS ONE 2013;8(11):e81710
Boschert V et al
2013/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
92 Ishikawa M et al. Pannexin 3 inhibits proliferation of osteoprogenitor cells by regulating Wnt and p21 signaling. J. Biol. Chem. 2014 Jan;289(5):2839-51
Ishikawa M et al
2014/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
93 Han XH et al. Regulation of the follistatin gene by RSPO-LGR4 signaling via activation of the WNT/β-catenin pathway in skeletal myogenesis. Mol. Cell. Biol. 2014 Feb;34(4):752-64
Han XH et al
2014/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
94 Kohler EE et al. Flk1+ and VE-cadherin+ endothelial cells derived from iPSCs recapitulates vascular development during differentiation and display similar angiogenic potential as ESC-derived cells. PLoS ONE 2013;8(12):e85549
Kohler EE et al
2013/01/01
Application: In Vivo, Sample Type: In Vivo PubMed
95 Dhamdhere GR et al. Drugging a stem cell compartment using Wnt3a protein as a therapeutic. PLoS ONE 2014;9(1):e83650
Dhamdhere GR et al
2014/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
96 Lei NY et al. Intestinal subepithelial myofibroblasts support the growth of intestinal epithelial stem cells. PLoS ONE 2014;9(1):e84651
Lei NY et al
2014/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
97 Stapp AD et al. Canonical WNT signaling inhibits follicle stimulating hormone mediated steroidogenesis in primary cultures of rat granulosa cells. PLoS ONE 2014;9(1):e86432
Stapp AD et al
2014/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
98 Raggioli A et al. Beta-catenin is vital for the integrity of mouse embryonic stem cells. PLoS ONE 2014;9(1):e86691
Raggioli A et al
2014/01/01
Application: Bioassay, Sample Type: Cell culture PubMed
99 Chen J et al. WNT7B promotes bone formation in part through mTORC1. PLoS Genet. 2014 Jan;10(1):e1004145
Chen J et al
2014/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
100 Go GW et al. The combined hyperlipidemia caused by impaired Wnt-LRP6 signaling is reversed by Wnt3a rescue. Cell Metab. 2014 Feb;19(2):209-20
Go GW et al
2014/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
101 Liu Y et al. Hhex and Cer1 mediate the Sox17 pathway for cardiac mesoderm formation in embryonic stem cells. Stem Cells 2014 Jun;32(6):1515-26
Liu Y et al
2014/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
102 Tsakiridis A et al. Distinct Wnt-driven primitive streak-like populations reflect in vivo lineage precursors. Development 2014 Mar;141(6):1209-21
Tsakiridis A et al
2014/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
103 Lewandowski JP et al. Manipulating gene expression and signaling activity in cultured mouse limb bud cells. Dev. Dyn. 2014 Jul;243(7):928-36
Lewandowski JP et al
2014/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
104 Yu CH et al. Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4. Eur. J. Immunol. 2014 May;44(5):1480-90
Yu CH et al
2014/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
105 Okamoto M et al. Noncanonical Wnt5a enhances Wnt/β-catenin signaling during osteoblastogenesis. Sci Rep 2014;4:4493
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106 Koraishy FM et al. Hepatocyte growth factor (Hgf) stimulates low density lipoprotein receptor-related protein (Lrp) 5/6 phosphorylation and promotes canonical Wnt signaling. J. Biol. Chem. 2014 May;289(20):14341-50
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107 Bentzinger CF et al. Wnt7a stimulates myogenic stem cell motility and engraftment resulting in improved muscle strength. J. Cell Biol. 2014 Apr;205(1):97-111
Bentzinger CF et al
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108 Liu N et al. Wnt/β-catenin pathway regulates cementogenic differentiation of adipose tissue-deprived stem cells in dental follicle cell-conditioned medium. PLoS ONE 2014;9(5):e93364
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109 Mich JK et al. Prospective identification of functionally distinct stem cells and neurosphere-initiating cells in adult mouse forebrain. Elife 2014;3:e02669
Mich JK et al
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110 Poh YC et al. Generation of organized germ layers from a single mouse embryonic stem cell. Nat Commun 2014;5:4000
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111 Zhu Y et al. Phosphatase WIP1 regulates adult neurogenesis and WNT signaling during aging. J. Clin. Invest. 2014 Jul;124(7):3263-73
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112 Gao B et al. Dose-dependent effect of estrogen suppresses the osteo-adipogenic transdifferentiation of osteoblasts via canonical Wnt signaling pathway. PLoS ONE 2014;9(6):e99137
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113 Zhu Q et al. The transcription factor Pou3f1 promotes neural fate commitment via activation of neural lineage genes and inhibition of external signaling pathways. Elife 2014;3
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114 Bainbridge TW et al. Evolutionary divergence in the catalytic activity of the CAM-1, ROR1 and ROR2 kinase domains. PLoS ONE 2014;9(7):e102695
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115 Cambier L et al. Nkx2-5 regulates cardiac growth through modulation of Wnt signaling by R-spondin3. Development 2014 Aug;141(15):2959-71
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116 Komiya Y et al. Custos controls β-catenin to regulate head development during vertebrate embryogenesis. Proc. Natl. Acad. Sci. U.S.A. 2014 Sep;111(36):13099-104
Komiya Y et al
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117 Gouti M et al. In vitro generation of neuromesodermal progenitors reveals distinct roles for wnt signalling in the specification of spinal cord and paraxial mesoderm identity. PLoS Biol. 2014 Aug;12(8):e1001937
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118 Noguchi H et al. Induction of tissue-specific stem cells by reprogramming factors, and tissue-specific selection. Cell Death Differ. 2015 Jan;22(1):145-55
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119 Ramsey SA et al. Epigenome-guided analysis of the transcriptome of plaque macrophages during atherosclerosis regression reveals activation of the Wnt signaling pathway. PLoS Genet. 2014 Dec;10(12):e1004828
Ramsey SA et al
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120 Alshbool FZ et al. Differential expression of claudin family members during osteoblast and osteoclast differentiation: Cldn-1 is a novel positive regulator of osteoblastogenesis. PLoS ONE 2014;9(12):e114357
Alshbool FZ et al
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121 Inagaki T et al. The FBXL10/KDM2B Scaffolding Protein Associates with Novel Polycomb Repressive Complex-1 to Regulate Adipogenesis. J. Biol. Chem. 2015 Feb;290(7):4163-77
Inagaki T et al
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122 Tao S et al. Wnt activity and basal niche position sensitize intestinal stem and progenitor cells to DNA damage. EMBO J. 2015 Mar;34(5):624-40
Tao S et al
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123 Zhang L et al. Inhibited Wnt signaling causes age-dependent abnormalities in the bone matrix mineralization in the Apert syndrome FGFR2(S252W/+) mice. PLoS ONE 2015;10(2):e112716
Zhang L et al
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124 Suryawanshi A et al. Canonical wnt signaling in dendritic cells regulates Th1/Th17 responses and suppresses autoimmune neuroinflammation. J. Immunol. 2015 Apr;194(7):3295-304
Suryawanshi A et al
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125 Suzuki A et al. WNT/β-Catenin Signaling Regulates Multiple Steps of Myogenesis by Regulating Step-Specific Targets. Mol. Cell. Biol. 2015 May;35(10):1763-76
Suzuki A et al
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126 Schafer ST et al. The Wnt adaptor protein ATP6AP2 regulates multiple stages of adult hippocampal neurogenesis. J. Neurosci. 2015 Mar;35(12):4983-98
Schafer ST et al
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127 Amador-Arjona A et al. SOX2 primes the epigenetic landscape in neural precursors enabling proper gene activation during hippocampal neurogenesis. Proc. Natl. Acad. Sci. U.S.A. 2015 Apr;112(15):E1936-45
Amador-Arjona A et al
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128 Chang B et al. Epsin is required for Dishevelled stability and Wnt signalling activation in colon cancer development. Nat Commun 2015;6:6380
Chang B et al
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129 Gortazar AR et al. Crosstalk between caveolin-1/extracellular signal-regulated kinase (ERK) and β-catenin survival pathways in osteocyte mechanotransduction. J. Biol. Chem. 2013 Mar;288(12):8168-75
Gortazar AR et al
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130 Weinert S et al. Transport activity and presence of ClC-7/Ostm1 complex account for different cellular functions. EMBO Rep. 2014 Jul;15(7):784-91
Weinert S et al
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131 Ouji Y et al. Partial maintenance and long-term expansion of murine skin epithelial stem cells by Wnt-3a in vitro. J. Invest. Dermatol. 2015 Jun;135(6):1598-608
Ouji Y et al
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132 Kim HY et al. CXXC5 is a negative-feedback regulator of the Wnt/β-catenin pathway involved in osteoblast differentiation. Cell Death Differ. 2015 Jun;22(6):912-20
Kim HY et al
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133 Lu WY et al. Hepatic progenitor cells of biliary origin with liver repopulation capacity. Nat. Cell Biol. 2015 Aug;17(8):971-83
Lu WY et al
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134 Morrison G et al. Convergence of cMyc and β-catenin on Tcf7l1 enables endoderm specification. EMBO J. 2016 Jan;35(3):356-68
Morrison G et al
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135 Beier EE et al. Heavy Metal Ion Regulation of Gene Expression: MECHANISMS BY WHICH LEAD INHIBITS OSTEOBLASTIC BONE-FORMING ACTIVITY THROUGH MODULATION OF THE Wnt/β-CATENIN SIGNALING PATHWAY. J. Biol. Chem. 2015 Jul;290(29):18216-26
Beier EE et al
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136 Attayek PJ et al. In Vitro Polarization of Colonoids to Create an Intestinal Stem Cell Compartment. PLoS ONE 2016;11(4):e0153795
Attayek PJ et al
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137 Cai T et al. WNT/β-catenin signaling promotes VSMCs to osteogenic transdifferentiation and calcification through directly modulating Runx2 gene expression. Exp. Cell Res. 2016 Jul;345(2):206-17
Cai T et al
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138 Bonney S et al. Diverse Functions of Retinoic Acid in Brain Vascular Development. J. Neurosci. 2016 Jul;36(29):7786-801
Bonney S et al
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139 Gong J et al. Pigment Epithelium-derived Factor (PEDF) Blocks Wnt3a Protein-induced Autophagy in Pancreatic Intraepithelial Neoplasms. J. Biol. Chem. 2016 Oct;291(42):22074-22085
Gong J et al
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140 Matsumoto T et al. Retinol Promotes In Vitro Growth of Proximal Colon Organoids through a Retinoic Acid-Independent Mechanism. PLoS ONE 2016;11(8):e0162049
Matsumoto T et al
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141 Saitoh I et al. Tissue-Specific Stem Cells Obtained by Reprogramming of Non-Obese Diabetic (NOD) Mouse-Derived Pancreatic Cells Confer Insulin Production in Response to Glucose. PLoS ONE ;11(9):e0163580
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142 Muruganandan S et al. Chemokine-Like Receptor 1 Is a Novel Wnt Target Gene that Regulates Mesenchymal Stem Cell Differentiation. Stem Cells 2017 Mar;35(3):711-724
Muruganandan S et al
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143 Himburg HA et al. Dickkopf-1 promotes hematopoietic regeneration via direct and niche-mediated mechanisms. Nat. Med. 2017 Jan;23(1):91-99
Himburg HA et al
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144 Rodr鱈guez-Colman MJ et al. Interplay between metabolic identities in the intestinal crypt supports stem cell function. Nature 2017 03;543(7645):424-427
Rodr鱈guez-Colman MJ et al
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145 Lacour F et al. R-spondin1 Controls Muscle Cell Fusion through Dual Regulation of Antagonistic Wnt Signaling Pathways. Cell Rep 2017 Mar;18(10):2320-2330
Lacour F et al
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146 Li L et al. Acceleration of bone regeneration by activating Wnt/β-catenin signalling pathway via lithium released from lithium chloride/calcium phosphate cement in osteoporosis. Sci Rep 2017 Mar;7:45204
Li L et al
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147 Furtado MB et al. Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling. JCI Insight 2017 Mar;2(6):e88271
Furtado MB et al
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148 Wilk K et al. Postnatal Calvarial Skeletal Stem Cells Expressing PRX1 Reside Exclusively in the Calvarial Sutures and Are Required for Bone Regeneration. Stem Cell Reports 2017 Apr;8(4):933-946
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149 McCauley KB et al. Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling. Cell Stem Cell 2017 Jun;20(6):844-857.e6
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    Liu BY et al. The transforming activity of Wnt effectors correlates with their ability to induce the accumulation of mammary progenitor cells. Proc. Natl. Acad. Sci. U.S.A. 2004 Mar;101(12):4158-63
    Liu BY et al
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    Species: Mouse, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Winkler DG et al. Sclerostin inhibition of Wnt-3a-induced C3H10T1/2 cell differentiation is indirect and mediated by bone morphogenetic proteins. J. Biol. Chem. 2005 Jan;280(4):2498-502
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    Species: Mouse, Application: Bioassay, Whole Cells
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    PubMed
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    Shimizu T et al. Wnt signaling controls the timing of oligodendrocyte development in the spinal cord. Dev. Biol. 2005 Jun;282(2):397-410
    Shimizu T et al
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    Species: Mouse, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Lowry WE et al. Defining the impact of beta-catenin/Tcf transactivation on epithelial stem cells. Genes Dev. 2005 Jul;19(13):1596-611
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    PubMed
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    Dravid G et al. Defining the role of Wnt/beta-catenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cells. Stem Cells ;23(10):1489-501
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    PubMed
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    Capurro MI et al. Glypican-3 promotes the growth of hepatocellular carcinoma by stimulating canonical Wnt signaling. Cancer Res. 2005 Jul;65(14):6245-54
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    Species: Human, Application: Binding Assay, Whole Cells
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    PubMed
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    Hall CL et al. Prostate cancer cells promote osteoblastic bone metastases through Wnts. Cancer Res. 2005 Sep;65(17):7554-60
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Corti S et al. Multipotentiality, homing properties, and pyramidal neurogenesis of CNS-derived LeX(ssea-1)+/CXCR4+ stem cells. FASEB J. 2005 Nov;19(13):1860-2
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    PubMed
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    Inoue T et al. Activation of canonical Wnt pathway promotes proliferation of retinal stem cells derived from adult mouse ciliary margin. Stem Cells 2006 Jan;24(1):95-104
    Inoue T et al
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Yue Z et al. Wnt3a gradient converts radial to bilateral feather symmetry via topological arrangement of epithelia. Proc. Natl. Acad. Sci. U.S.A. 2006 Jan;103(4):951-5
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    PubMed
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    Luo Y et al. SDF1alpha/CXCR4 signaling stimulates beta-catenin transcriptional activity in rat neural progenitors. Neurosci. Lett. 2006 May;398(3):291-5
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Ogawa K et al. Synergistic action of Wnt and LIF in maintaining pluripotency of mouse ES cells. Biochem. Biophys. Res. Commun. 2006 Apr;343(1):159-66
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Lu J et al. Defined culture conditions of human embryonic stem cells. Proc. Natl. Acad. Sci. U.S.A. 2006 Apr;103(15):5688-93
    Lu J et al
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Liu Y et al. A novel chemical-defined medium with bFGF and N2B27 supplements supports undifferentiated growth in human embryonic stem cells. Biochem. Biophys. Res. Commun. 2006 Jul;346(1):131-9
    Liu Y et al
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Oloumi A et al. Modulation of Wnt3a-mediated nuclear beta-catenin accumulation and activation by integrin-linked kinase in mammalian cells. Oncogene 2006 Dec;25(59):7747-57
    Oloumi A et al
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Tong M et al. Histone deacetylase inhibitors and transforming growth factor-beta induce 15-hydroxyprostaglandin dehydrogenase expression in human lung adenocarcinoma cells. Biochem. Pharmacol. 2006 Sep;72(6):701-9
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    Species: Human, Application: Bioassay, Whole Cells
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    PubMed
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    Dejmek J et al. Wnt-5a/Ca2+-induced NFAT activity is counteracted by Wnt-5a/Yes-Cdc42-casein kinase 1alpha signaling in human mammary epithelial cells. Mol. Cell. Biol. 2006 Aug;26(16):6024-36
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Nordstr旦m U et al. An early role for WNT signaling in specifying neural patterns of Cdx and Hox gene expression and motor neuron subtype identity. PLoS Biol. 2006 Jul;4(8):e252
    Nordstr旦m U et al
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  • 備考:
    Species: Chicken, Application: Bioassay, Whole Tissue
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    PubMed
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    Hasegawa K et al. A method for the selection of human embryonic stem cell sublines with high replating efficiency after single-cell dissociation. Stem Cells 2006 Dec;24(12):2649-60
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    Species: Human, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Wang Y et al. Epm2a suppresses tumor growth in an immunocompromised host by inhibiting Wnt signaling. Cancer Cell 2006 Sep;10(3):179-90
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    Species: Mouse, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Kim SE et al. The PI3 kinase-Akt pathway mediates Wnt3a-induced proliferation. Cell. Signal. 2007 Mar;19(3):511-8
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    PubMed
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    Sato A et al. Profilin is an effector for Daam1 in non-canonical Wnt signaling and is required for vertebrate gastrulation. Development 2006 Nov;133(21):4219-31
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Bryja V et al. Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin. Cell. Signal. 2007 Mar;19(3):610-6
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    PubMed
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    Nygren MK et al. Wnt3A activates canonical Wnt signalling in acute lymphoblastic leukaemia (ALL) cells and inhibits the proliferation of B-ALL cell lines. Br. J. Haematol. 2007 Feb;136(3):400-13
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    Species: Human, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Kousteni S et al. Induction of osteoblast differentiation by selective activation of kinase-mediated actions of the estrogen receptor. Mol. Cell. Biol. 2007 Feb;27(4):1516-30
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    PubMed
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    Abe K et al. NMDA-receptor activation induces calpain-mediated beta-catenin cleavages for triggering gene expression. Neuron 2007 Feb;53(3):387-97
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    Species: Mouse, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Miyabayashi T et al. Wnt/beta-catenin/CBP signaling maintains long-term murine embryonic stem cell pluripotency. Proc. Natl. Acad. Sci. U.S.A. 2007 Mar;104(13):5668-73
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    Species: Mouse, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Canning CA et al. Sustained interactive Wnt and FGF signaling is required to maintain isthmic identity. Dev. Biol. 2007 May;305(1):276-86
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    Species: Chicken, Application: Bioassay, Sample type: Whole Tissue
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    PubMed
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    Osakada F et al. Wnt signaling promotes regeneration in the retina of adult mammals. J. Neurosci. 2007 Apr;27(15):4210-9
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    Species: Rat, Application: Bioassay, Sample type: Whole Tissue
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    Wawrzak D et al. Wnt3a binds to several sFRPs in the nanomolar range. Biochem. Biophys. Res. Commun. 2007 Jun;357(4):1119-23
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    Rydziel S et al. Nephroblastoma overexpressed (Nov) inhibits osteoblastogenesis and causes osteopenia. J. Biol. Chem. 2007 Jul;282(27):19762-72
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    Species: Mouse, Application: Bioassay, Sample type: GST and GST-Nov Fusion proteins, Whole Cells
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    PubMed
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    Kwon C et al. Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors. Proc. Natl. Acad. Sci. U.S.A. 2007 Jun;104(26):10894-9
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    Species: Mouse, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Giuliani N et al. Production of Wnt inhibitors by myeloma cells: potential effects on canonical Wnt pathway in the bone microenvironment. Cancer Res. 2007 Aug;67(16):7665-74
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    Species: Human, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Inoue T et al. Media conditioned by retinal pigment epithelial cells suppress the canonical Wnt pathway. Neurosci. Lett. 2007 Sep;424(3):190-3
    Inoue T et al
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    Species: Human, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Binnerts ME et al. R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6. Proc. Natl. Acad. Sci. U.S.A. 2007 Sep;104(37):14700-5
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    Species: Human, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Zhang P et al. Short-term BMP-4 treatment initiates mesoderm induction in human embryonic stem cells. Blood 2008 Feb;111(4):1933-41
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    Species: Human, Application: Bioassay, Whole Cells
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    PubMed
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    Cho YM et al. Betacellulin and nicotinamide sustain PDX1 expression and induce pancreatic beta-cell differentiation in human embryonic stem cells. Biochem. Biophys. Res. Commun. 2008 Feb;366(1):129-34
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    Species: Human, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Anderson BC et al. Myogenic growth factors can decrease extraocular muscle force generation: a potential biological approach to the treatment of strabismus. Invest. Ophthalmol. Vis. Sci. 2008 Jan;49(1):221-9
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    Species: Rabbit, Application: In Vivo
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    PubMed
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    Endo Y et al. Wnt-3a and Dickkopf-1 stimulate neurite outgrowth in Ewing tumor cells via a Frizzled3- and c-Jun N-terminal kinase-dependent mechanism. Mol. Cell. Biol. 2008 Apr;28(7):2368-79
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    Verkaar F et al. Stably overexpressed human Frizzled-2 signals through the beta-catenin pathway and does not activate Ca2+-mobilization in Human Embryonic Kidney 293 cells. Cell. Signal. 2009 Jan;21(1):22-33
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    Wexler EM et al. Endogenous Wnt signaling maintains neural progenitor cell potency. Stem Cells 2009 May;27(5):1130-41
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    Tsai SY et al. Single transcription factor reprogramming of hair follicle dermal papilla cells to induced pluripotent stem cells. Stem Cells 2011 Jun;29(6):964-71
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    Application: cell culture, Sample Type: whole cells
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    Application: Bioassay, Sample Type: Cell culture
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    Application: Bioassay, Sample Type: Whole Cells
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    Application: Bioassay, Sample Type: Whole Cells
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    Application: Bioassay, Sample Type: Whole Cells
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    Kohler EE et al. Flk1+ and VE-cadherin+ endothelial cells derived from iPSCs recapitulates vascular development during differentiation and display similar angiogenic potential as ESC-derived cells. PLoS ONE 2013;8(12):e85549
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    Application: In Vivo, Sample Type: In Vivo
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    Stapp AD et al. Canonical WNT signaling inhibits follicle stimulating hormone mediated steroidogenesis in primary cultures of rat granulosa cells. PLoS ONE 2014;9(1):e86432
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    Chen J et al. WNT7B promotes bone formation in part through mTORC1. PLoS Genet. 2014 Jan;10(1):e1004145
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    Application: Bioassay, Sample Type: Whole Cells
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    Application: Bioassay, Sample Type: Whole Cells
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    Application: Bioassay, Sample Type: Whole Cells
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    Bentzinger CF et al. Wnt7a stimulates myogenic stem cell motility and engraftment resulting in improved muscle strength. J. Cell Biol. 2014 Apr;205(1):97-111
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    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
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    Liu N et al. Wnt/β-catenin pathway regulates cementogenic differentiation of adipose tissue-deprived stem cells in dental follicle cell-conditioned medium. PLoS ONE 2014;9(5):e93364
    Liu N et al
    2014/01/01
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Mich JK et al. Prospective identification of functionally distinct stem cells and neurosphere-initiating cells in adult mouse forebrain. Elife 2014;3:e02669
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Poh YC et al. Generation of organized germ layers from a single mouse embryonic stem cell. Nat Commun 2014;5:4000
    Poh YC et al
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Zhu Y et al. Phosphatase WIP1 regulates adult neurogenesis and WNT signaling during aging. J. Clin. Invest. 2014 Jul;124(7):3263-73
    Zhu Y et al
    2014/01/01
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    Application: Bioassay, Sample Type: Whole Cell
  • 参照:
    PubMed
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  • 文献情報:
    Gao B et al. Dose-dependent effect of estrogen suppresses the osteo-adipogenic transdifferentiation of osteoblasts via canonical Wnt signaling pathway. PLoS ONE 2014;9(6):e99137
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    Application: Bioassay, Sample Type: Cell culture
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    PubMed
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    Zhu Q et al. The transcription factor Pou3f1 promotes neural fate commitment via activation of neural lineage genes and inhibition of external signaling pathways. Elife 2014;3
    Zhu Q et al
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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  • 文献情報:
    Bainbridge TW et al. Evolutionary divergence in the catalytic activity of the CAM-1, ROR1 and ROR2 kinase domains. PLoS ONE 2014;9(7):e102695
    Bainbridge TW et al
    2014/01/01
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    Application: in vitro assay, Sample Type: Whole Cells
  • 参照:
    PubMed
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    Cambier L et al. Nkx2-5 regulates cardiac growth through modulation of Wnt signaling by R-spondin3. Development 2014 Aug;141(15):2959-71
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    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
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    Komiya Y et al. Custos controls β-catenin to regulate head development during vertebrate embryogenesis. Proc. Natl. Acad. Sci. U.S.A. 2014 Sep;111(36):13099-104
    Komiya Y et al
    2014/01/01
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    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
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    Gouti M et al. In vitro generation of neuromesodermal progenitors reveals distinct roles for wnt signalling in the specification of spinal cord and paraxial mesoderm identity. PLoS Biol. 2014 Aug;12(8):e1001937
    Gouti M et al
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Noguchi H et al. Induction of tissue-specific stem cells by reprogramming factors, and tissue-specific selection. Cell Death Differ. 2015 Jan;22(1):145-55
    Noguchi H et al
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    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
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    Ramsey SA et al. Epigenome-guided analysis of the transcriptome of plaque macrophages during atherosclerosis regression reveals activation of the Wnt signaling pathway. PLoS Genet. 2014 Dec;10(12):e1004828
    Ramsey SA et al
    2014/01/01
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    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
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  • 文献情報:
    Alshbool FZ et al. Differential expression of claudin family members during osteoblast and osteoclast differentiation: Cldn-1 is a novel positive regulator of osteoblastogenesis. PLoS ONE 2014;9(12):e114357
    Alshbool FZ et al
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Inagaki T et al. The FBXL10/KDM2B Scaffolding Protein Associates with Novel Polycomb Repressive Complex-1 to Regulate Adipogenesis. J. Biol. Chem. 2015 Feb;290(7):4163-77
    Inagaki T et al
    2015/01/01
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    Application: inhibit adipogenesis, Sample Type: Cell culture
  • 参照:
    PubMed
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    Tao S et al. Wnt activity and basal niche position sensitize intestinal stem and progenitor cells to DNA damage. EMBO J. 2015 Mar;34(5):624-40
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    Application: Bioassay, Sample Type: Cell culture
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    PubMed
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    Zhang L et al. Inhibited Wnt signaling causes age-dependent abnormalities in the bone matrix mineralization in the Apert syndrome FGFR2(S252W/+) mice. PLoS ONE 2015;10(2):e112716
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    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
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    Suryawanshi A et al. Canonical wnt signaling in dendritic cells regulates Th1/Th17 responses and suppresses autoimmune neuroinflammation. J. Immunol. 2015 Apr;194(7):3295-304
    Suryawanshi A et al
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    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
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    Suzuki A et al. WNT/β-Catenin Signaling Regulates Multiple Steps of Myogenesis by Regulating Step-Specific Targets. Mol. Cell. Biol. 2015 May;35(10):1763-76
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    Application: Bioassay, Sample Type: Cell Culture Supernates
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    PubMed
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    Schafer ST et al. The Wnt adaptor protein ATP6AP2 regulates multiple stages of adult hippocampal neurogenesis. J. Neurosci. 2015 Mar;35(12):4983-98
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Amador-Arjona A et al. SOX2 primes the epigenetic landscape in neural precursors enabling proper gene activation during hippocampal neurogenesis. Proc. Natl. Acad. Sci. U.S.A. 2015 Apr;112(15):E1936-45
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Chang B et al. Epsin is required for Dishevelled stability and Wnt signalling activation in colon cancer development. Nat Commun 2015;6:6380
    Chang B et al
    2015/01/01
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Gortazar AR et al. Crosstalk between caveolin-1/extracellular signal-regulated kinase (ERK) and β-catenin survival pathways in osteocyte mechanotransduction. J. Biol. Chem. 2013 Mar;288(12):8168-75
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Weinert S et al. Transport activity and presence of ClC-7/Ostm1 complex account for different cellular functions. EMBO Rep. 2014 Jul;15(7):784-91
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Ouji Y et al. Partial maintenance and long-term expansion of murine skin epithelial stem cells by Wnt-3a in vitro. J. Invest. Dermatol. 2015 Jun;135(6):1598-608
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Kim HY et al. CXXC5 is a negative-feedback regulator of the Wnt/β-catenin pathway involved in osteoblast differentiation. Cell Death Differ. 2015 Jun;22(6):912-20
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Lu WY et al. Hepatic progenitor cells of biliary origin with liver repopulation capacity. Nat. Cell Biol. 2015 Aug;17(8):971-83
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Morrison G et al. Convergence of cMyc and β-catenin on Tcf7l1 enables endoderm specification. EMBO J. 2016 Jan;35(3):356-68
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Beier EE et al. Heavy Metal Ion Regulation of Gene Expression: MECHANISMS BY WHICH LEAD INHIBITS OSTEOBLASTIC BONE-FORMING ACTIVITY THROUGH MODULATION OF THE Wnt/β-CATENIN SIGNALING PATHWAY. J. Biol. Chem. 2015 Jul;290(29):18216-26
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Attayek PJ et al. In Vitro Polarization of Colonoids to Create an Intestinal Stem Cell Compartment. PLoS ONE 2016;11(4):e0153795
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    Application: Bioassay, Sample Type: Whole Tissue
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    PubMed
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    Cai T et al. WNT/β-catenin signaling promotes VSMCs to osteogenic transdifferentiation and calcification through directly modulating Runx2 gene expression. Exp. Cell Res. 2016 Jul;345(2):206-17
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Bonney S et al. Diverse Functions of Retinoic Acid in Brain Vascular Development. J. Neurosci. 2016 Jul;36(29):7786-801
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    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
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    Gong J et al. Pigment Epithelium-derived Factor (PEDF) Blocks Wnt3a Protein-induced Autophagy in Pancreatic Intraepithelial Neoplasms. J. Biol. Chem. 2016 Oct;291(42):22074-22085
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    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
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    Matsumoto T et al. Retinol Promotes In Vitro Growth of Proximal Colon Organoids through a Retinoic Acid-Independent Mechanism. PLoS ONE 2016;11(8):e0162049
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    Application: Bioassay, Sample Type: Whole Tissue
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    PubMed
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    Saitoh I et al. Tissue-Specific Stem Cells Obtained by Reprogramming of Non-Obese Diabetic (NOD) Mouse-Derived Pancreatic Cells Confer Insulin Production in Response to Glucose. PLoS ONE ;11(9):e0163580
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    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
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    Muruganandan S et al. Chemokine-Like Receptor 1 Is a Novel Wnt Target Gene that Regulates Mesenchymal Stem Cell Differentiation. Stem Cells 2017 Mar;35(3):711-724
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    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
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    Himburg HA et al. Dickkopf-1 promotes hematopoietic regeneration via direct and niche-mediated mechanisms. Nat. Med. 2017 Jan;23(1):91-99
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    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
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    Rodr鱈guez-Colman MJ et al. Interplay between metabolic identities in the intestinal crypt supports stem cell function. Nature 2017 03;543(7645):424-427
    Rodr鱈guez-Colman MJ et al
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Lacour F et al. R-spondin1 Controls Muscle Cell Fusion through Dual Regulation of Antagonistic Wnt Signaling Pathways. Cell Rep 2017 Mar;18(10):2320-2330
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    2017/01/01
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    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
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  • 文献情報:
    Li L et al. Acceleration of bone regeneration by activating Wnt/β-catenin signalling pathway via lithium released from lithium chloride/calcium phosphate cement in osteoporosis. Sci Rep 2017 Mar;7:45204
    Li L et al
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    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
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  • 文献情報:
    Furtado MB et al. Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling. JCI Insight 2017 Mar;2(6):e88271
    Furtado MB et al
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  • 備考:
    Application: Bioassay, Sample Type: Cell Lysates
  • 参照:
    PubMed
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  • 文献情報:
    Wilk K et al. Postnatal Calvarial Skeletal Stem Cells Expressing PRX1 Reside Exclusively in the Calvarial Sutures and Are Required for Bone Regeneration. Stem Cell Reports 2017 Apr;8(4):933-946
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    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
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    McCauley KB et al. Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling. Cell Stem Cell 2017 Jun;20(6):844-857.e6
    McCauley KB et al
    2017/01/01
  • 備考:
    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed