Leptin, Mouse, Recombinant, Carrier-free <OB>

データシート

• 商品コード：498-OB-05M
• メーカー：RSD
• 包装：5mg
• 価格： ¥141,000
• 在庫：無(未発注)

マイリストに追加 マイリストに追加済

• No.： 1
• 文献情報：
  Lin S et al. Development of high fat diet-induced obesity and leptin resistance in C57Bl/6J mice. Int. J. Obes. Relat. Metab. Disord. 2000 May;24(5):639-46
  Lin S et al
  2000/01/01
  
• 備考：
  Application: In Vivo, Sample Type: In Vivo
• 参照：
  

• No.： 2
• 文献情報：
  Matarese G et al. Leptin accelerates autoimmune diabetes in female NOD mice. Diabetes 2002 May;51(5):1356-61
  Matarese G et al
  2002/01/01
  
• 備考：
  Application: In Vivo
• 参照：
  

• No.： 3
• 文献情報：
  Kaser S et al. Interferon-alpha suppresses leptin levels: studies in interferon-alpha treated patients with hepatitis C virus infection and murine adipocytes. Eur. Cytokine Netw. ;13(2):225-9
  Kaser S et al
  
• 備考：
  Application: ELISA Standard
• 参照：
  

• No.： 4
• 文献情報：
  Kveiborg M et al. The increased bone mass in deltaFosB transgenic mice is independent of circulating leptin levels. Endocrinology 2002 Nov;143(11):4304-9
  Kveiborg M et al
  2002/01/01
  
• 備考：
  Application: In Vivo
• 参照：
  

• No.： 5
• 文献情報：
  Wang W et al. Role of leptin deficiency in early acute renal failure during endotoxemia in ob/ob mice. J. Am. Soc. Nephrol. 2004 Mar;15(3):645-9
  Wang W et al
  2004/01/01
  
• 備考：
  Application: In Vivo
• 参照：
  

• No.： 6
• 文献情報：
  Mistr鱈k P et al. BiaCore analysis of leptin-leptin receptor interaction: evidence for 1:1 stoichiometry. Anal. Biochem. 2004 Apr;327(2):271-7
  Mistr鱈k P et al
  2004/01/01
  
• 備考：
  Species: Human, Mouse, Application: Biacore binding study, Sample type: recombinant Leptin Receptor
• 参照：
  

• No.： 7
• 文献情報：
  De Rosa V et al. Leptin neutralization interferes with pathogenic T cell autoreactivity in autoimmune encephalomyelitis. J. Clin. Invest. 2006 Feb;116(2):447-55
  De Rosa V et al
  2006/01/01
  
• 備考：
  Application: Antibody generation
• 参照：
  

• No.： 8
• 文献情報：
  Lamghari M et al. Leptin effect on RANKL and OPG expression in MC3T3-E1 osteoblasts. J. Cell. Biochem. 2006 Aug;98(5):1123-9
  Lamghari M et al
  2006/01/01
  
• 備考：
  Species: Mouse, Application: Bioassay, Sample type: Whole Cells
• 参照：
  

• No.： 9
• 文献情報：
  Raju SV et al. Activation of the cardiac ciliary neurotrophic factor receptor reverses left ventricular hypertrophy in leptin-deficient and leptin-resistant obesity. Proc. Natl. Acad. Sci. U.S.A. 2006 Mar;103(11):4222-7
  Raju SV et al
  2006/01/01
  
• 備考：
  Application: In Vivo
• 参照：
  

• No.： 10
• 文献情報：
  Xu AW et al. Inactivation of signal transducer and activator of transcription 3 in proopiomelanocortin (Pomc) neurons causes decreased pomc expression, mild obesity, and defects in compensatory refeeding. Endocrinology 2007 Jan;148(1):72-80
  Xu AW et al
  2007/01/01
  
• 備考：
  Application: In Vivo
• 参照：
  

• No.： 11
• 文献情報：
  Bodary PF et al. Leptin regulates neointima formation after arterial injury through mechanisms independent of blood pressure and the leptin receptor/STAT3 signaling pathways involved in energy balance. Arterioscler. Thromb. Vasc. Biol. 2007 Jan;27(1):70-6
  Bodary PF et al
  2007/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 12
• 文献情報：
  Abe Y et al. Leptin induces elongation of cardiac myocytes and causes eccentric left ventricular dilatation with compensation. Am. J. Physiol. Heart Circ. Physiol. 2007 May;292(5):H2387-96
  Abe Y et al
  2007/01/01
  
• 備考：
  Species: Mouse, Application: In Vivo, Sample type: In Vivo
• 参照：
  

• No.： 13
• 文献情報：
  Cariou B et al. FXR-deficiency confers increased susceptibility to torpor. FEBS Lett. 2007 Nov;581(27):5191-8
  Cariou B et al
  2007/01/01
  
• 備考：
  Species: Mouse, Application: In Vivo, In Vivo
• 参照：
  

• No.： 14
• 文献情報：
  Yu IC et al. Hyperleptinemia without obesity in male mice lacking androgen receptor in adipose tissue. Endocrinology 2008 May;149(5):2361-8
  Yu IC et al
  2008/01/01
  
• 備考：
  Species: Mouse, Application: In Vivo
• 参照：
  

• No.： 15
• 文献情報：
  Fenton JI et al. Adiponectin blocks multiple signaling cascades associated with leptin-induced cell proliferation in Apc Min/+ colon epithelial cells. Int. J. Cancer 2008 Jun;122(11):2437-45
  Fenton JI et al
  2008/01/01
  
• 備考：
  Species: Mouse, Application: Bioassay, Whole Cells
• 参照：
  

• No.： 16
• 文献情報：
  Zhang W et al. Adipose tissue gene expression profiles in ob/ob mice treated with leptin. Life Sci. 2008 Jul;83(1-2):35-42
  Zhang W et al
  2008/01/01
  
• 備考：
  Species: Mouse, Application: In Vivo, Buffer
• 参照：
  

• No.： 17
• 文献情報：
  Feng D et al. Stearoyl-CoA desaturase 1 deficiency protects mice from immune-mediated liver injury. Lab. Invest. 2009 Feb;89(2):222-30
  Feng D et al
  2009/01/01
  
• 備考：
  Application: In Vivo, Sample Type: In Vivo
• 参照：
  

• No.： 18
• 文献情報：
  Narvekar P et al. Liver-specific loss of lipolysis-stimulated lipoprotein receptor triggers systemic hyperlipidemia in mice. Diabetes 2009 May;58(5):1040-9
  Narvekar P et al
  2009/01/01
  
• 備考：
  Application: Bioassay, Sample Type: In Vivo
• 参照：
  

• No.： 19
• 文献情報：
  Kiguchi N et al. Leptin enhances CC-chemokine ligand expression in cultured murine macrophage. Biochem. Biophys. Res. Commun. 2009 Jul;384(3):311-5
  Kiguchi N et al
  2009/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 20
• 文献情報：
  Neels JG et al. Keratinocyte-derived chemokine in obesity: expression, regulation, and role in adipose macrophage infiltration and glucose homeostasis. J. Biol. Chem. 2009 Jul;284(31):20692-8
  Neels JG et al
  2009/01/01
  
• 備考：
  Application: Bioassay, Sample Type: In Vivo
• 参照：
  

• No.： 21
• 文献情報：
  Gruver AL et al. Leptin receptor is expressed in thymus medulla and leptin protects against thymic remodeling during endotoxemia-induced thymus involution. J. Endocrinol. 2009 Oct;203(1):75-85
  Gruver AL et al
  2009/01/01
  
• 備考：
  Application: In Vivo
• 参照：
  

• No.： 22
• 文献情報：
  Pini M et al. Enhanced production of IL-17A during zymosan-induced peritonitis in obese mice. J. Leukoc. Biol. 2010 Jan;87(1):51-8
  Pini M et al
  2010/01/01
  
• 備考：
  Application: In Vivo, Sample Type: In Vivo
• 参照：
  

• No.： 23
• 文献情報：
  Unger EK et al. Functional role of c-Jun-N-terminal kinase in feeding regulation. Endocrinology 2010 Feb;151(2):671-82
  Unger EK et al
  2010/01/01
  
• 備考：
  Application: In Vivo, Sample Type: In Vivo
• 参照：
  

• No.： 24
• 文献情報：
  Kim KS et al. Enhanced hypothalamic leptin signaling in mice lacking dopamine D2 receptors. J. Biol. Chem. 2010 Mar;285(12):8905-17
  Kim KS et al
  2010/01/01
  
• 備考：
  Application: Bioassay,In Vivo, Sample Type: In Vivo,Whole Cells
• 参照：
  

• No.： 25
• 文献情報：
  Shapiro NI et al. Leptin exacerbates sepsis-mediated morbidity and mortality. J. Immunol. 2010 Jul;185(1):517-24
  Shapiro NI et al
  2010/01/01
  
• 備考：
  Application: In Vivo, Sample Type: In Vivo
• 参照：
  

• No.： 26
• 文献情報：
  Li X et al. Intracerebroventricular leptin infusion improves glucose homeostasis in lean type 2 diabetic MKR mice via hepatic vagal and non-vagal mechanisms. PLoS ONE 2011;6(2):e17058
  Li X et al
  2011/01/01
  
• 備考：
  Application: In Vivo, Sample Type: In Vivo
• 参照：
  

• No.： 27
• 文献情報：
  Blouet C et al. Nutrient-sensing hypothalamic TXNIP links nutrient excess to energy imbalance in mice. J. Neurosci. 2011 Apr;31(16):6019-27
  Blouet C et al
  2011/01/01
  
• 備考：
  Application: In Vivo, Sample Type: In Vivo
• 参照：
  

• No.： 28
• 文献情報：
  Owen C et al. Adipocyte-specific protein tyrosine phosphatase 1B deletion increases lipogenesis, adipocyte cell size and is a minor regulator of glucose homeostasis. PLoS ONE 2012;7(2):e32700
  Owen C et al
  2012/01/01
  
• 備考：
  Application: In Vivo, Sample Type: In Vivo
• 参照：
  

• No.： 29
• 文献情報：
  Zhang Y et al. BBS mutations modify phenotypic expression of CEP290-related ciliopathies. Hum. Mol. Genet. 2014 Jan;23(1):40-51
  Zhang Y et al
  2014/01/01
  
• 備考：
  Application: In vivo injection, Sample Type: Whole Organism
• 参照：
  

• No.： 30
• 文献情報：
  Wang L et al. PAQR3 has modulatory roles in obesity, energy metabolism, and leptin signaling. Endocrinology 2013 Dec;154(12):4525-35
  Wang L et al
  2013/01/01
  
• 備考：
  Application: Bioassay, Sample Type: In Vivo
• 参照：
  

• No.： 31
• 文献情報：
  Gonzalez-Quesada C et al. Thrombospondin-1 induction in the diabetic myocardium stabilizes the cardiac matrix in addition to promoting vascular rarefaction through angiopoietin-2 upregulation. Circ. Res. 2013 Dec;113(12):1331-44
  Gonzalez-Quesada C et al
  2013/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Cell culture
• 参照：
  

• No.： 32
• 文献情報：
  Moraes-Vieira PM et al. Leptin deficiency impairs maturation of dendritic cells and enhances induction of regulatory T and Th17 cells. Eur. J. Immunol. 2014 Mar;44(3):794-806
  Moraes-Vieira PM et al
  2014/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 33
• 文献情報：
  Fujita Y et al. Deficient leptin signaling ameliorates systemic lupus erythematosus lesions in MRL/Mp-Fas lpr mice. J. Immunol. 2014 Feb;192(3):979-84
  Fujita Y et al
  2014/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 34
• 文献情報：
  Hosoi T et al. Flurbiprofen ameliorated obesity by attenuating leptin resistance induced by endoplasmic reticulum stress. EMBO Mol Med 2014 Mar;6(3):335-46
  Hosoi T et al
  2014/01/01
  
• 備考：
  Application: In vivo injection, Sample Type: In Vivo
• 参照：
  

• No.： 35
• 文献情報：
  Yuan M et al. Hyperleptinemia directly affects testicular maturation at different sexual stages in mice, and suppressor of cytokine signaling 3 is involved in this process. Reprod. Biol. Endocrinol. 2014;12:15
  Yuan M et al
  2014/01/01
  
• 備考：
  Application: In vitro, Sample Type: Whole Tissue
• 参照：
  

• No.： 36
• 文献情報：
  Han YM et al. Leptin-promoted cilia assembly is critical for normal energy balance. J. Clin. Invest. 2014 May;124(5):2193-7
  Han YM et al
  2014/01/01
  
• 備考：
  Application: In Vivo, Sample Type: In Vivo
• 参照：
  

• No.： 37
• 文献情報：
  Briggs DI et al. Evidence that diet-induced hyperleptinemia, but not hypothalamic gliosis, causes ghrelin resistance in NPY/AgRP neurons of male mice. Endocrinology 2014 Jul;155(7):2411-22
  Briggs DI et al
  2014/01/01
  
• 備考：
  Application: In vivo injection, Sample Type: In Vivo
• 参照：
  

• No.： 38
• 文献情報：
  Verkerke H et al. Kinetics of leptin binding to the Q223R leptin receptor. PLoS ONE 2014;9(4):e94843
  Verkerke H et al
  2014/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 39
• 文献情報：
  Yoshino S et al. Protection against high-fat diet-induced obesity in Helz2-deficient male mice due to enhanced expression of hepatic leptin receptor. Endocrinology 2014 Sep;155(9):3459-72
  Yoshino S et al
  2014/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 40
• 文献情報：
  Falcone JA et al. Intranasal administration as a route for drug delivery to the brain: evidence for a unique pathway for albumin. J. Pharmacol. Exp. Ther. 2014 Oct;351(1):54-60
  Falcone JA et al
  2014/01/01
  
• 備考：
  Application: In Vivo, Sample Type: In Vivo
• 参照：
  

• No.： 41
• 文献情報：
  Tillman EJ et al. Three months of high-fructose feeding fails to induce excessive weight gain or leptin resistance in mice. PLoS ONE 2014;9(9):e107206
  Tillman EJ et al
  2014/01/01
  
• 備考：
  Application: In Vivo, Sample Type: Whole Organism
• 参照：
  

• No.： 42
• 文献情報：
  Mejia P et al. Dietary restriction protects against experimental cerebral malaria via leptin modulation and T-cell mTORC1 suppression. Nat Commun 2015;6:6050
  Mejia P et al
  2015/01/01
  
• 備考：
  Application: In vivo injection, Sample Type: Whole Organism
• 参照：
  

• No.： 43
• 文献情報：
  Tadokoro S et al. Leptin promotes wound healing in the skin. PLoS ONE 2015;10(3):e0121242
  Tadokoro S et al
  2015/01/01
  
• 備考：
  Application: Bioassay, Sample Type: tissue
• 参照：
  

• No.： 44
• 文献情報：
  Kim MS et al. Rapid linkage of innate immunological signals to adaptive immunity by the brain-fat axis. Nat. Immunol. 2015 May;16(5):525-33
  Kim MS et al
  2015/01/01
  
• 備考：
  Application: In Vivo, Sample Type: In Vivo
• 参照：
  

• No.： 45
• 文献情報：
  Li D et al. Specific Interaction between eEF1A and HIV RT Is Critical for HIV-1 Reverse Transcription and a Potential Anti-HIV Target. PLoS Pathog. 2015 Dec;11(12):e1005289
  Li D et al
  2015/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 46
• 文献情報：
  Zheng M et al. Carbon monoxide-releasing molecules reverse leptin resistance induced by endoplasmic reticulum stress. Am. J. Physiol. Endocrinol. Metab. 2013 Apr;304(7):E780-8
  Zheng M et al
  2013/01/01
  
• 備考：
  Application: In Vivo, Sample Type: In Vivo
• 参照：
  

• No.： 47
• 文献情報：
  Wang M et al. Salidroside improves glucose homeostasis in obese mice by repressing inflammation in white adipose tissues and improving leptin sensitivity in hypothalamus. Sci Rep 2016 May;6:25399
  Wang M et al
  2016/01/01
  
• 備考：
  Application: In Vivo, Sample Type: In Vivo
• 参照：
  

• No.： 48
• 文献情報：
  Gerriets VA et al. Leptin directly promotes T-cell glycolytic metabolism to drive effector T-cell differentiation in a mouse model of autoimmunity. Eur. J. Immunol. 2016 Aug;46(8):1970-83
  Gerriets VA et al
  2016/01/01
  
• 備考：
  Application: In Vivo, Sample Type: In Vivo
• 参照：
  

• No.： 49
• 文献情報：
  Lu Z et al. Fasting selectively blocks development of acute lymphoblastic leukemia via leptin-receptor upregulation. Nat. Med. 2017 Jan;23(1):79-90
  Lu Z et al
  2017/01/01
  
• 備考：
  Application: In Vivo, Sample Type: In Vivo
• 参照：
  

• No.： 50
• 文献情報：
  Raciti GA et al. Specific CpG hyper-methylation leads to Ankrd26 gene down-regulation in white adipose tissue of a mouse model of diet-induced obesity. Sci Rep 2017 Mar;7:43526
  Raciti GA et al
  2017/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 51
• 文献情報：
  Mosialou I et al. MC4R-dependent suppression of appetite by bone-derived lipocalin 2. Nature 2017 03;543(7645):385-390
  Mosialou I et al
  2017/01/01
  
• 備考：
  Application: Control, Sample Type: Whole Cells
• 参照：
  

• No.： 52
• 文献情報：
  Xie G et al. Loss of pericyte smoothened activity in mice with genetic deficiency of leptin. BMC Cell Biol. 2017 Apr;18(1):20
  Xie G et al
  2017/01/01
  
• 備考：
  Application: Bioassay,In Vivo, Sample Type: In Vivo,Whole Cells
• 参照：