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在庫・価格 : 2024年05月27日 21時33分 現在

商品名 商品コード メーカー 包装 価格 在庫 リスト
Z-Trp-Glu(OMe)-His-Asp(OMe)-FMK, Trifluoroacetate <Z-WEHD-FMK> <Caspase-1 Inhibitor>
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FMK002 RSDアールアンドディー システムス
R&D Systems, Inc.
1 mg ¥56,000
(未発注)
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在庫・価格 : 2024年05月27日 21時33分 現在

Z-Trp-Glu(OMe)-His-Asp(OMe)-FMK, Trifluoroacetate <Z-WEHD-FMK> <Caspase-1 Inhibitor>

  • 商品コード:FMK002
  • メーカー:RSD
  • 包装:1mg
  • 価格: ¥56,000
  • 在庫:無(未発注)
使用文献
No. 文献情報 備考 参照
1 Vergote D et al. (-)-Epigallocatechin (EGC) of green tea induces apoptosis of human breast cancer cells but not of their normal counterparts. Breast Cancer Res. Treat. 2002 Dec;76(3):195-201
Vergote D et al
2002/01/01
Sample Type: Whole Cells PubMed
2 Aguzzi MS et al. RGDS peptide induces caspase 8 and caspase 9 activation in human endothelial cells. Blood 2004 Jun;103(11):4180-7
Aguzzi MS et al
2004/01/01
Sample Type: Whole Cells PubMed
3 Jin H et al. Induction of immature dendritic cell apoptosis by foot and mouth disease virus is an integrin receptor mediated event before viral infection. J. Cell. Biochem. 2007 Nov;102(4):980-91
Jin H et al
2007/01/01
Species: Mouse, Sample type: Cell Lysates PubMed
4 Cho MH et al. Bacillus anthracis capsule activates caspase-1 and induces interleukin-1beta release from differentiated THP-1 and human monocyte-derived dendritic cells. Infect. Immun. 2010 Jan;78(1):387-92
Cho MH et al
2010/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
5 Kim MJ et al. Active caspase-1-mediated secretion of retinoic acid inducible gene-I. J. Immunol. 2008 Nov;181(10):7324-31
Kim MJ et al
2008/01/01
Application: Bioassay, Sample Type: whole cells PubMed
6 Mukherjee P et al. Activation of the innate signaling molecule MAVS by bunyavirus infection upregulates the adaptor protein SARM1, leading to neuronal death. Immunity 2013 Apr;38(4):705-16
Mukherjee P et al
2013/01/01
Sample Type: Whole Cells PubMed
7 Jitprasertwong P et al. Leptin enhances the secretion of interleukin (IL)-18, but not IL-1&#x3B2;, from human monocytes via activation of caspase-1. Cytokine 2014 Feb;65(2):222-30
Jitprasertwong P et al
2014/01/01
Sample Type: Cell Lysates PubMed
8 Xia M et al. Endothelial NLRP3 inflammasome activation and enhanced neointima formation in mice by adipokine visfatin. Am. J. Pathol. 2014 May;184(5):1617-28
Xia M et al
2014/01/01
Sample Type: Whole Cells PubMed
9 Teigler JE et al. Late endosomal trafficking of alternative serotype adenovirus vaccine vectors augments antiviral innate immunity. J. Virol. 2014 Sep;88(18):10354-63
Teigler JE et al
2014/01/01
Sample Type: Whole Cells PubMed
10 Winter SE et al. The flagellar regulator TviA reduces pyroptosis by Salmonella enterica serovar Typhi. Infect. Immun. 2015 Apr;83(4):1546-55
Winter SE et al
2015/01/01
Sample Type: Whole Cells PubMed
11 Callaway JB et al. Spleen Tyrosine Kinase (Syk) Mediates IL-1&#x3B2; Induction by Primary Human Monocytes during Antibody-enhanced Dengue Virus Infection. J. Biol. Chem. 2015 Jul;290(28):17306-20
Callaway JB et al
2015/01/01
Sample Type: Whole Cells PubMed
12 Callaway JB et al. Source and Purity of Dengue-Viral Preparations Impact Requirement for Enhancing Antibody to Induce Elevated IL-1&#x3B2; Secretion: A Primary Human Monocyte Model. PLoS ONE 2015;10(8):e0136708
Callaway JB et al
2015/01/01
Sample Type: Whole Cells PubMed
13 Gonz叩lez-Juarbe N et al. Pore-Forming Toxins Induce Macrophage Necroptosis during Acute Bacterial Pneumonia. PLoS Pathog. 2015 Dec;11(12):e1005337
Gonz叩lez-Juarbe N et al
2015/01/01
Sample Type: Whole Cells PubMed
14 Kofahi HM et al. Hepatitis C Virus Infection of Cultured Human Hepatoma Cells Causes Apoptosis and Pyroptosis in Both Infected and Bystander Cells. Sci Rep 2016 Dec;6:37433
Kofahi HM et al
2016/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
15 Gonzalez-Juarbe N et al. Bacterial Pore-Forming Toxins Promote the Activation of Caspases in Parallel to Necroptosis to Enhance Alarmin Release and Inflammation During Pneumonia. Sci Rep 2018 Apr;8(1):5846
Gonzalez-Juarbe N et al
2018/01/01
Species: Human, Applications: Bioassay PubMed
16 Kang Y et al. Telomere Dysfunction Disturbs Macrophage Mitochondrial Metabolism and the NLRP3 Inflammasome through the PGC-1&#x3B1;/TNFAIP3 Axis. Cell Rep 2018 Mar;22(13):3493-3506
Kang Y et al
2018/01/01
Species: Mouse, Applications: Bioassay PubMed
17 Cross SN et al. Viral Infection Sensitizes Human Fetal Membranes to Bacterial Lipopolysaccharide by MERTK Inhibition and Inflammasome Activation. J. Immunol. 2017 Oct;199(8):2885-2895
Cross SN et al
2017/01/01
Species: Human, Applications: Bioassay PubMed
18 Soto R et al. Microbiota promotes systemic T-cell survival through suppression of an apoptotic factor. Proc. Natl. Acad. Sci. U.S.A. 2017 05;114(21):5497-5502
Soto R et al
2017/01/01
Species: Mouse, Applications: Bioassay PubMed
19 Corleis B et al. HIV-1 and SIV Infection Are Associated with Early Loss of Lung Interstitial CD4+ T Cells and Dissemination of Pulmonary Tuberculosis. Cell Rep 2019 Feb;26(6):1409-1418.e5
Corleis B et al
2019/01/01
PubMed
20 Dornhof R et al. Stress fibers, autophagy and necrosis by persistent exposure to PM2.5 from biomass combustion. PLoS ONE 2017;12(7):e0180291
Dornhof R et al
2017/01/01
PubMed
21 Boini KM et al. Trimethylamine-N-Oxide Instigates NLRP3 Inflammasome Activation and Endothelial Dysfunction. Cell. Physiol. Biochem. 2017;44(1):152-162
Boini KM et al
2017/01/01
PubMed
22 Scott LM et al. Production and regulation of interleukin-1 family cytokines at the materno-fetal interface. Cytokine 2017 Nov;99:194-202
Scott LM et al
2017/01/01
PubMed
23 Ferko MA et al. Effects of metal ions on caspase-1 activation and interleukin-1&#x3B2; release in murine bone marrow-derived macrophages. PLoS ONE 2018;13(8):e0199936
Ferko MA et al
2018/01/01
PubMed
24 Czimmerer Z et al. The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages. Immunity 2018 01;48(1):75-90.e6
Czimmerer Z et al
2018/01/01
PubMed
25 Talley S et al. A Caspase-1 Biosensor to Monitor the Progression of Inflammation In Vivo. J Immunol 2019 11;203(9):2497-2507
Talley S et al
2019/01/01
PubMed
26 Lavallard V et al. NLRP3 Inflammasome is Activated in Rat Pancreatic Islets by Transplantation and Hypoxia. Sci Rep 2020 04;10(1):7011
Lavallard V et al
2020/01/01
Species: Mouse, Applications: Bioassay PubMed
27 Xu C et al. The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity. Cell Rep 2021 Jun;35(11):109235
Xu C et al
2021/01/01
Species: Mouse, Applications: Bioassay PubMed
28 Abrahams VM et al. NLRP3 inflammasome function and pyroptotic cell death in human placental Hofbauer cells. J Reprod Immunol 2020 11;142:103214
Abrahams VM et al
2020/01/01
Species: Human, Applications: Bioassay PubMed
  • No.: 1
  • 文献情報:
    Vergote D et al. (-)-Epigallocatechin (EGC) of green tea induces apoptosis of human breast cancer cells but not of their normal counterparts. Breast Cancer Res. Treat. 2002 Dec;76(3):195-201
    Vergote D et al
    2002/01/01
  • 備考:
    Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 2
  • 文献情報:
    Aguzzi MS et al. RGDS peptide induces caspase 8 and caspase 9 activation in human endothelial cells. Blood 2004 Jun;103(11):4180-7
    Aguzzi MS et al
    2004/01/01
  • 備考:
    Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 3
  • 文献情報:
    Jin H et al. Induction of immature dendritic cell apoptosis by foot and mouth disease virus is an integrin receptor mediated event before viral infection. J. Cell. Biochem. 2007 Nov;102(4):980-91
    Jin H et al
    2007/01/01
  • 備考:
    Species: Mouse, Sample type: Cell Lysates
  • 参照:
    PubMed
  • No.: 4
  • 文献情報:
    Cho MH et al. Bacillus anthracis capsule activates caspase-1 and induces interleukin-1beta release from differentiated THP-1 and human monocyte-derived dendritic cells. Infect. Immun. 2010 Jan;78(1):387-92
    Cho MH et al
    2010/01/01
  • 備考:
    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 5
  • 文献情報:
    Kim MJ et al. Active caspase-1-mediated secretion of retinoic acid inducible gene-I. J. Immunol. 2008 Nov;181(10):7324-31
    Kim MJ et al
    2008/01/01
  • 備考:
    Application: Bioassay, Sample Type: whole cells
  • 参照:
    PubMed
  • No.: 6
  • 文献情報:
    Mukherjee P et al. Activation of the innate signaling molecule MAVS by bunyavirus infection upregulates the adaptor protein SARM1, leading to neuronal death. Immunity 2013 Apr;38(4):705-16
    Mukherjee P et al
    2013/01/01
  • 備考:
    Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 7
  • 文献情報:
    Jitprasertwong P et al. Leptin enhances the secretion of interleukin (IL)-18, but not IL-1&#x3B2;, from human monocytes via activation of caspase-1. Cytokine 2014 Feb;65(2):222-30
    Jitprasertwong P et al
    2014/01/01
  • 備考:
    Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 8
  • 文献情報:
    Xia M et al. Endothelial NLRP3 inflammasome activation and enhanced neointima formation in mice by adipokine visfatin. Am. J. Pathol. 2014 May;184(5):1617-28
    Xia M et al
    2014/01/01
  • 備考:
    Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 9
  • 文献情報:
    Teigler JE et al. Late endosomal trafficking of alternative serotype adenovirus vaccine vectors augments antiviral innate immunity. J. Virol. 2014 Sep;88(18):10354-63
    Teigler JE et al
    2014/01/01
  • 備考:
    Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 10
  • 文献情報:
    Winter SE et al. The flagellar regulator TviA reduces pyroptosis by Salmonella enterica serovar Typhi. Infect. Immun. 2015 Apr;83(4):1546-55
    Winter SE et al
    2015/01/01
  • 備考:
    Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 11
  • 文献情報:
    Callaway JB et al. Spleen Tyrosine Kinase (Syk) Mediates IL-1&#x3B2; Induction by Primary Human Monocytes during Antibody-enhanced Dengue Virus Infection. J. Biol. Chem. 2015 Jul;290(28):17306-20
    Callaway JB et al
    2015/01/01
  • 備考:
    Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 12
  • 文献情報:
    Callaway JB et al. Source and Purity of Dengue-Viral Preparations Impact Requirement for Enhancing Antibody to Induce Elevated IL-1&#x3B2; Secretion: A Primary Human Monocyte Model. PLoS ONE 2015;10(8):e0136708
    Callaway JB et al
    2015/01/01
  • 備考:
    Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 13
  • 文献情報:
    Gonz叩lez-Juarbe N et al. Pore-Forming Toxins Induce Macrophage Necroptosis during Acute Bacterial Pneumonia. PLoS Pathog. 2015 Dec;11(12):e1005337
    Gonz叩lez-Juarbe N et al
    2015/01/01
  • 備考:
    Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 14
  • 文献情報:
    Kofahi HM et al. Hepatitis C Virus Infection of Cultured Human Hepatoma Cells Causes Apoptosis and Pyroptosis in Both Infected and Bystander Cells. Sci Rep 2016 Dec;6:37433
    Kofahi HM et al
    2016/01/01
  • 備考:
    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 15
  • 文献情報:
    Gonzalez-Juarbe N et al. Bacterial Pore-Forming Toxins Promote the Activation of Caspases in Parallel to Necroptosis to Enhance Alarmin Release and Inflammation During Pneumonia. Sci Rep 2018 Apr;8(1):5846
    Gonzalez-Juarbe N et al
    2018/01/01
  • 備考:
    Species: Human, Applications: Bioassay
  • 参照:
    PubMed
  • No.: 16
  • 文献情報:
    Kang Y et al. Telomere Dysfunction Disturbs Macrophage Mitochondrial Metabolism and the NLRP3 Inflammasome through the PGC-1&#x3B1;/TNFAIP3 Axis. Cell Rep 2018 Mar;22(13):3493-3506
    Kang Y et al
    2018/01/01
  • 備考:
    Species: Mouse, Applications: Bioassay
  • 参照:
    PubMed
  • No.: 17
  • 文献情報:
    Cross SN et al. Viral Infection Sensitizes Human Fetal Membranes to Bacterial Lipopolysaccharide by MERTK Inhibition and Inflammasome Activation. J. Immunol. 2017 Oct;199(8):2885-2895
    Cross SN et al
    2017/01/01
  • 備考:
    Species: Human, Applications: Bioassay
  • 参照:
    PubMed
  • No.: 18
  • 文献情報:
    Soto R et al. Microbiota promotes systemic T-cell survival through suppression of an apoptotic factor. Proc. Natl. Acad. Sci. U.S.A. 2017 05;114(21):5497-5502
    Soto R et al
    2017/01/01
  • 備考:
    Species: Mouse, Applications: Bioassay
  • 参照:
    PubMed
  • No.: 19
  • 文献情報:
    Corleis B et al. HIV-1 and SIV Infection Are Associated with Early Loss of Lung Interstitial CD4+ T Cells and Dissemination of Pulmonary Tuberculosis. Cell Rep 2019 Feb;26(6):1409-1418.e5
    Corleis B et al
    2019/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 20
  • 文献情報:
    Dornhof R et al. Stress fibers, autophagy and necrosis by persistent exposure to PM2.5 from biomass combustion. PLoS ONE 2017;12(7):e0180291
    Dornhof R et al
    2017/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 21
  • 文献情報:
    Boini KM et al. Trimethylamine-N-Oxide Instigates NLRP3 Inflammasome Activation and Endothelial Dysfunction. Cell. Physiol. Biochem. 2017;44(1):152-162
    Boini KM et al
    2017/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 22
  • 文献情報:
    Scott LM et al. Production and regulation of interleukin-1 family cytokines at the materno-fetal interface. Cytokine 2017 Nov;99:194-202
    Scott LM et al
    2017/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 23
  • 文献情報:
    Ferko MA et al. Effects of metal ions on caspase-1 activation and interleukin-1&#x3B2; release in murine bone marrow-derived macrophages. PLoS ONE 2018;13(8):e0199936
    Ferko MA et al
    2018/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 24
  • 文献情報:
    Czimmerer Z et al. The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages. Immunity 2018 01;48(1):75-90.e6
    Czimmerer Z et al
    2018/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 25
  • 文献情報:
    Talley S et al. A Caspase-1 Biosensor to Monitor the Progression of Inflammation In Vivo. J Immunol 2019 11;203(9):2497-2507
    Talley S et al
    2019/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 26
  • 文献情報:
    Lavallard V et al. NLRP3 Inflammasome is Activated in Rat Pancreatic Islets by Transplantation and Hypoxia. Sci Rep 2020 04;10(1):7011
    Lavallard V et al
    2020/01/01
  • 備考:
    Species: Mouse, Applications: Bioassay
  • 参照:
    PubMed
  • No.: 27
  • 文献情報:
    Xu C et al. The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity. Cell Rep 2021 Jun;35(11):109235
    Xu C et al
    2021/01/01
  • 備考:
    Species: Mouse, Applications: Bioassay
  • 参照:
    PubMed
  • No.: 28
  • 文献情報:
    Abrahams VM et al. NLRP3 inflammasome function and pyroptotic cell death in human placental Hofbauer cells. J Reprod Immunol 2020 11;142:103214
    Abrahams VM et al
    2020/01/01
  • 備考:
    Species: Human, Applications: Bioassay
  • 参照:
    PubMed