Z-Val-Ala-Asp(OMe)-FMK <Z-VAD-FMK> <General Caspase Inhibitor>

データシート※最新のデータシートでない場合があります

• 商品コード：FMK001
• メーカー：RSD
• 包装：1mg
• 価格： ¥33,000
• 在庫：無(未発注)

マイリストに追加 マイリストに追加済

• No.： 1
• 文献情報：
  O&#39;Hara SP et al. The transcription factor ETS1 promotes apoptosis resistance of senescent cholangiocytes by epigenetically up-regulating the apoptosis suppressor BCL2L1. J Biol Chem 2019 12;294(49):18698-18713
  O&#39;Hara SP et al
  2019/01/01
  
• 備考：
  
• 参照：
  

• No.： 2
• 文献情報：
  Choi SJ et al. Pseudolaric Acid B Induces Growth Inhibition and Caspase-Dependent Apoptosis on Head and Neck Cancer Cell lines through Death Receptor 5. Molecules 2019 Oct;24(20)
  Choi SJ et al
  2019/01/01
  
• 備考：
  
• 参照：
  

• No.： 3
• 文献情報：
  Kim DE et al. Deficiency in the DNA repair protein ERCC1 triggers a link between senescence and apoptosis in human fibroblasts and mouse skin. Aging Cell 2020 03;19(3):e13072
  Kim DE et al
  2020/01/01
  
• 備考：
  
• 参照：
  

• No.： 4
• 文献情報：
  Cho HR et al. 7-Oxygenated cholesterol molecules differentially affect the expression of zonula occludens-1 in vascular smooth muscle cells and monocyte/macrophage cells. Biochem Biophys Res Commun 2018 03;497(2):521-526
  Cho HR et al
  2018/01/01
  
• 備考：
  
• 参照：
  

• No.： 5
• 文献情報：
  Lakhter AJ et al. Beta cell extracellular vesicle miR-21-5p cargo is increased in response to inflammatory cytokines and serves as a biomarker of type 1 diabetes. Diabetologia 2018 05;61(5):1124-1134
  Lakhter AJ et al
  2018/01/01
  
• 備考：
  
• 参照：
  

• No.： 6
• 文献情報：
  Tsuchiya K et al. Caspase-1 initiates apoptosis in the absence of gasdermin D. Nat Commun 2019 05;10(1):2091
  Tsuchiya K et al
  2019/01/01
  
• 備考：
  
• 参照：
  

• No.： 7
• 文献情報：
  Lee AR et al. Lercanidipine Synergistically Enhances Bortezomib Cytotoxicity in Cancer Cells via Enhanced Endoplasmic Reticulum Stress and Mitochondrial Ca²⁺ Overload. Int J Mol Sci 2019 Dec;20(24)
  Lee AR et al
  2019/01/01
  
• 備考：
  
• 参照：
  

• No.： 8
• 文献情報：
  Cho HD et al. Solid state fermentation process with Aspergillus kawachii enhances the cancer-suppressive potential of silkworm larva in hepatocellular carcinoma cells. BMC Complement Altern Med 2019 Sep;19(1):241
  Cho HD et al
  2019/01/01
  
• 備考：
  
• 参照：
  

• No.： 9
• 文献情報：
  Woo SM et al. Axl Inhibitor R428 Enhances TRAIL-Mediated Apoptosis Through Downregulation of c-FLIP and Survivin Expression in Renal Carcinoma. Int J Mol Sci 2019 Jul;20(13)
  Woo SM et al
  2019/01/01
  
• 備考：
  
• 参照：
  

• No.： 10
• 文献情報：
  Madhi R et al. Platelet IP6K1 regulates neutrophil extracellular trap-microparticle complex formation in acute pancreatitis. JCI Insight 2019 Oct;
  Madhi R et al
  2019/01/01
  
• 備考：
  
• 参照：
  

• No.： 11
• 文献情報：
  Shin JW et al. BCI induces apoptosis via generation of reactive oxygen species and activation of intrinsic mitochondrial pathway in H1299 lung cancer cells. Sci China Life Sci 2018 Oct;61(10):1243-1253
  Shin JW et al
  2018/01/01
  
• 備考：
  
• 参照：
  

• No.： 12
• 文献情報：
  Dileepan M et al. Regulation of Eosinophil Recruitment and Allergic Airway Inflammation by Tropomyosin Receptor Kinase A. J Immunol 2020 02;204(3):682-693
  Dileepan M et al
  2020/01/01
  
• 備考：
  
• 参照：
  

• No.： 13
• 文献情報：
  Yan S et al. PFKFB3 Inhibition Attenuates Oxaliplatin-Induced Autophagy and Enhances Its Cytotoxicity in Colon Cancer Cells. Int J Mol Sci 2019 Oct;20(21)
  Yan S et al
  2019/01/01
  
• 備考：
  
• 参照：
  

• No.： 14
• 文献情報：
  Kratochv鱈lov叩 A et al. Osteogenic impact of pro-apoptotic caspase inhibitors in MC3T3-E1 cells. Sci Rep 2020 05;10(1):7489
  Kratochv鱈lov叩 A et al
  2020/01/01
  
• 備考：
  
• 参照：
  

• No.： 15
• 文献情報：
  Riegger J et al. Evidence of necroptosis in osteoarthritic disease: investigation of blunt mechanical impact as possible trigger in regulated necrosis. Cell Death Dis 2019 Sep;10(10):683
  Riegger J et al
  2019/01/01
  
• 備考：
  
• 参照：
  

• No.： 16
• 文献情報：
  Mann J et al. BAD sensitizes breast cancer cells to docetaxel with increased mitotic arrest and necroptosis. Sci Rep 2020 01;10(1):355
  Mann J et al
  2020/01/01
  
• 備考：
  
• 参照：
  

• No.： 17
• 文献情報：
  Kim JH et al. Non-SMC condensin I complex subunit H mediates mature chromosome condensation and DNA damage in pancreatic cancer cells. Sci Rep 2019 11;9(1):17889
  Kim JH et al
  2019/01/01
  
• 備考：
  
• 参照：
  

• No.： 18
• 文献情報：
  Mittelstadt PR et al. Glucocorticoids Oppose Thymocyte Negative Selection by Inhibiting Helios and Nur77. J Immunol 2019 10;203(8):2163-2170
  Mittelstadt PR et al
  2019/01/01
  
• 備考：
  
• 参照：
  

• No.： 19
• 文献情報：
  Wang J et al. Skp2 depletion reduces tumor-initiating properties and promotes apoptosis in synovial sarcoma. Transl Oncol 2020 Oct;13(10):100809
  Wang J et al
  2020/01/01
  
• 備考：
  Species: Human
• 参照：
  

• No.： 20
• 文献情報：
  Xu Y et al. Novel Small Molecular Compound AE-848 Potently Induces Human Multiple Myeloma Cell Apoptosis by Modulating the NF-&#x3BA;B and PI3K/Akt/mTOR Signaling Pathways. Onco Targets Ther 2020;13:13063-13075
  Xu Y et al
  2020/01/01
  
• 備考：
  Species: Human, Applications: Cell Culture
• 参照：
  

• No.： 21
• 文献情報：
  Lee KM et al. Combined the SMAC mimetic and BCL2 inhibitor sensitizes neoadjuvant chemotherapy by targeting necrosome complexes in tyrosine aminoacyl-tRNA synthase-positive breast cancer. Breast Cancer Res 2020 11;22(1):130
  Lee KM et al
  2020/01/01
  
• 備考：
  Species: Human, Applications: Cell Culture
• 参照：
  

• No.： 22
• 文献情報：
  Iannuzzi CA et al. Pharmacological Inhibition of WEE1 Potentiates the Antitumoral Effect of the <i>dl922-947</i> Oncolytic Virus in Malignant Mesothelioma Cell Lines. Int J Mol Sci 2020 Oct;21(19)
  Iannuzzi CA et al
  2020/01/01
  
• 備考：
  Species: Human, Applications: Bioassay
• 参照：
  

• No.： 23
• 文献情報：
  Woo K et al. <i>N</i>-3-Hydroxy Dodecanoyl-DL-homoserine Lactone (OH-dDHL) Triggers Apoptosis of Bone Marrow-Derived Macrophages through the ER- and Mitochondria-Mediated Pathways. Int J Mol Sci 2021 Jul;22(14)
  Woo K et al
  2021/01/01
  
• 備考：
  Species: Mouse, Applications: Bioassay
• 参照：
  

• No.： 24
• 文献情報：
  Chen G et al. Netrin-1 receptor UNC5C cleavage by active &#x3B4;-secretase enhances neurodegeneration, promoting Alzheimer&#39;s disease pathologies. Sci Adv 2021 Apr;7(16)
  Chen G et al
  2021/01/01
  
• 備考：
  Species: Rat, Applications: Bioassay
• 参照：
  

• No.： 25
• 文献情報：
  Li Y et al. Selective Anti-Cancer Effects of Plasma-Activated Medium and Its High Efficacy with Cisplatin on Hepatocellular Carcinoma with Cancer Stem Cell Characteristics. Int J Mol Sci 2021 Apr;22(8)
  Li Y et al
  2021/01/01
  
• 備考：
  Species: Human, Applications: Bioassay
• 参照：
  

• No.： 26
• 文献情報：
  Xie G et al. Characterization of HIV-induced remodeling reveals differences in infection susceptibility of memory CD4⁺ T&#xA0;cell subsets in&#xA0;vivo. Cell Rep 2021 04;35(4):109038
  Xie G et al
  2021/01/01
  
• 備考：
  Species: Human, Applications: Bioassay
• 参照：
  

• No.： 27
• 文献情報：
  Lee H et al. Energy-stress-mediated AMPK activation inhibits ferroptosis. Nat Cell Biol 2020 02;22(2):225-234
  Lee H et al
  2020/01/01
  
• 備考：
  Species: Human, Applications: Bioassay
• 参照：
  

• No.： 28
• 文献情報：
  Jang JE et al. PERK/NRF2 and autophagy form a resistance mechanism against G9a inhibition in leukemia stem cells. J Exp Clin Cancer Res 2020 Apr;39(1):66
  Jang JE et al
  2020/01/01
  
• 備考：
  Species: Human, Applications: Cell Culture
• 参照：
  

• No.： 29
• 文献情報：
  Park SY et al. Reduction in MLKL-mediated endosomal trafficking enhances the TRAIL-DR4/5 signal to increase cancer cell death. Cell Death Dis 2020 09;11(9):744
  Park SY et al
  2020/01/01
  
• 備考：
  Species: Human, Applications: Bioassay
• 参照：
  

• No.： 30
• 文献情報：
  Sun J et al. The Pseudomonas aeruginosa protease LasB directly activates IL-1&#x3B2;. EBioMedicine 2020 Oct;60:102984
  Sun J et al
  2020/01/01
  
• 備考：
  Species: Mouse, Applications: Inhibition
• 参照：
  

• No.： 31
• 文献情報：
  Murai A et al. Synergistic apoptotic effects in cancer cells by the combination of CLK and Bcl-2 family inhibitors. PLoS One 2020;15(10):e0240718
  Murai A et al
  2020/01/01
  
• 備考：
  Species: Human, Applications: Cell Culture
• 参照：
  

• No.： 32
• 文献情報：
  Park HK et al. Combination of Arsenic Trioxide and Valproic Acid Efficiently Inhibits Growth of Lung Cancer Cells via G2/M-Phase Arrest and Apoptotic Cell Death. Int J Mol Sci 2020 Apr;21(7)
  Park HK et al
  2020/01/01
  
• 備考：
  Species: Human, Applications: Bioassay
• 参照：
  

• No.： 33
• 文献情報：
  Liu R et al. Monoglyceride lipase mediates tumor-suppressive effects by promoting degradation of X-linked inhibitor of apoptosis protein. Cell Death Differ 2020 10;27(10):2888-2903
  Liu R et al
  2020/01/01
  
• 備考：
  Species: Human
• 参照：
  

• No.： 34
• 文献情報：
  Liao C et al. Activation of JNK signaling promotes all-<i>trans-</i>retinal-induced photoreceptor apoptosis in mice. J Biol Chem 2020 05;295(20):6958-6971
  Liao C et al
  2020/01/01
  
• 備考：
  Species: Mouse, Applications: Bioassay
• 参照：
  

• No.： 35
• 文献情報：
  Min KJ et al. Induction of Lysosomal Membrane Permeabilization Is a Major Event of FTY720-Mediated Non-Apoptotic Cell Death in Human Glioma Cells. Cancers (Basel) 2020 Nov;12(11)
  Min KJ et al
  2020/01/01
  
• 備考：
  Species: Human, Applications: Bioassay
• 参照：
  

• No.： 36
• 文献情報：
  Kang JH et al. Dual role of phosphatidylserine and its receptors in osteoclastogenesis. Cell Death Dis 2020 07;11(7):497
  Kang JH et al
  2020/01/01
  
• 備考：
  Species: Mouse, Applications: Cell Culture
• 参照：