価格表

在庫・価格 : 2025年06月26日 23時00分 現在

商品名 商品コード メーカー 包装 価格 在庫 リスト
SLPI, Human, Recombinant, Carrier-free <Secretory Leukocyte Protease Inhibitor>
データシート
1274-PI-100 RSDアールアンドディー システムズ
R&D Systems, Inc.
100 μg ¥68,000 1個 追加

在庫・価格 : 2025年06月26日 23時00分 現在

SLPI, Human, Recombinant, Carrier-free <Secretory Leukocyte Protease Inhibitor>

  • 商品コード:1274-PI-100
  • メーカー:RSD
  • 包装:100μg
  • 価格: ¥68,000
  • 在庫:1個
使用文献
No. 文献情報 備考 参照
1 Hermant B et al. Identification of proteases involved in the proteolysis of vascular endothelium cadherin during neutrophil transmigration. J. Biol. Chem. 2003 Apr;278(16):14002-12
Hermant B et al
2003/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
2 Hirche TO et al. Deficiency in neutrophil elastase does not impair neutrophil recruitment to inflamed sites. Am. J. Respir. Cell Mol. Biol. 2004 Apr;30(4):576-84
Hirche TO et al
2004/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
3 Tam EM et al. Membrane protease proteomics: Isotope-coded affinity tag MS identification of undescribed MT1-matrix metalloproteinase substrates. Proc. Natl. Acad. Sci. U.S.A. 2004 May;101(18):6917-22
Tam EM et al
2004/01/01
Application: Enzyme Activity, Sample Type: Cell Supernates PubMed
4 Cortesio CL et al. Mannan-binding lectin-associated serine protease 3 cleaves synthetic peptides and insulin-like growth factor-binding protein 5. Arch. Biochem. Biophys. 2006 May;449(1-2):164-70
Cortesio CL et al
2006/01/01
Application: Enzyme Activity, Sample type: D10 affinity-matured variant of hVbeta2 PubMed
5 Into T et al. Arginine-specific gingipains from Porphyromonas gingivalis deprive protective functions of secretory leucocyte protease inhibitor in periodontal tissue. Clin. Exp. Immunol. 2006 Sep;145(3):545-54
Into T et al
2006/01/01
Species: Human, Application: Activity Assay, Sample type: Whole Cells PubMed
6 Xu W et al. Epithelial cells trigger frontline immunoglobulin class switching through a pathway regulated by the inhibitor SLPI. Nat. Immunol. 2007 Mar;8(3):294-303
Xu W et al
2007/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
7 Niemann CU et al. Neutrophil elastase depends on serglycin proteoglycan for localization in granules. Blood 2007 May;109(10):4478-86
Niemann CU et al
2007/01/01
Species: Mouse, Application: Enzyme Activity, Sample type: Cell Lysates PubMed
8 Fernie-King BA et al. Streptococcal DRS (distantly related to SIC) and SIC inhibit antimicrobial peptides, components of mucosal innate immunity: a comparison of their activities. Microbes Infect. 2007 Mar;9(3):300-7
Fernie-King BA et al
2007/01/01
Species: Bacteria, Application: Bioassay, Sample type: Whole Cells PubMed
9 Sugino T et al. The secretory leukocyte protease inhibitor (SLPI) suppresses cancer cell invasion but promotes blood-borne metastasis via an invasion-independent pathway. J. Pathol. 2007 Jun;212(2):152-60
Sugino T et al
2007/01/01
Species: Mouse, Application: Bioassay, Sample type: Whole Cells PubMed
10 Simpkins FA et al. The alarm anti-protease, secretory leukocyte protease inhibitor, is a proliferation and survival factor for ovarian cancer cells. Carcinogenesis 2008 Mar;29(3):466-72
Simpkins FA et al
2008/01/01
Species: Human, Application: Western Blot, Cell Lysates PubMed
11 Jacobsen LC et al. The secretory leukocyte protease inhibitor (SLPI) and the secondary granule protein lactoferrin are synthesized in myelocytes, colocalize in subcellular fractions of neutrophils, and are coreleased by activated neutrophils. J. Leukoc. B
Jacobsen LC et al
2008/01/01
Application: Western Blot Control PubMed
12 Nicol GR et al. Use of an immunoaffinity-mass spectrometry-based approach for the quantification of protein biomarkers from serum samples of lung cancer patients. Mol. Cell Proteomics 2008 Oct;7(10):1974-82
Nicol GR et al
2008/01/01
Application: Other: See notes, Sample Type: Buffer PubMed
13 Seto T et al. SLPI prevents cytokine release in mite protease-exposed conjunctival epithelial cells. Biochem. Biophys. Res. Commun. 2009 Feb;379(3):681-5
Seto T et al
2009/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
14 Rasool N et al. Secretory leukocyte protease inhibitor antagonizes paclitaxel in ovarian cancer cells. Clin. Cancer Res. 2010 Jan;16(2):600-9
Rasool N et al
2010/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
15 Vega-Carrascal I et al. Dysregulation of TIM-3-galectin-9 pathway in the cystic fibrosis airways. J. Immunol. 2011 Mar;186(5):2897-909
Vega-Carrascal I et al
2011/01/01
Application: Bioassay, Sample Type: BALF PubMed
16 M端ller AM et al. Inhibition of SLPI ameliorates disease activity in experimental autoimmune encephalomyelitis. BMC Neurosci 2012;13:30
M端ller AM et al
2012/01/01
Application: Bioassay,ELISA capture,In Vivo, Sample Type: In Vivo,Serum,Whole Cells PubMed
17 Suh HS et al. Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12). PLoS ONE 2012;7(4):e35115
Suh HS et al
2012/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
18 Hannila SS et al. Secretory leukocyte protease inhibitor reverses inhibition by CNS myelin, promotes regeneration in the optic nerve, and suppresses expression of the transforming growth factor-&#x3B2; signaling protein Smad2. J. Neurosci. 2013 Mar;33(12)
Hannila SS et al
2013/01/01
Application: Bioassay,In Vivo, Sample Type: Whole Cells,Whole Organism PubMed
19 Labidi-Galy SI et al. Elafin drives poor outcome in high-grade serous ovarian cancers and basal-like breast tumors. Oncogene 2015 Jan;34(3):373-83
Labidi-Galy SI et al
2015/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
20 Yang Y et al. Quantitative proteomic analysis of oral brush biopsies identifies secretory leukocyte protease inhibitor as a promising, mechanism-based oral cancer biomarker. PLoS ONE 2014;9(4):e95389
Yang Y et al
2014/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
21 Stapels DA et al. Staphylococcus aureus secretes a unique class of neutrophil serine protease inhibitors. Proc. Natl. Acad. Sci. U.S.A. 2014 Sep;111(36):13187-92
Stapels DA et al
2014/01/01
Application: Inhibitor, Sample Type: Protease in buffer PubMed
22 Woodham AW et al. Inhibition of Langerhans cell maturation by human papillomavirus type 16: a novel role for the annexin A2 heterotetramer in immune suppression. J. Immunol. 2014 May;192(10):4748-57
Woodham AW et al
2014/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
23 Vago JP et al. Proresolving Actions of Synthetic and Natural Protease Inhibitors Are Mediated by Annexin A1. J. Immunol. 2016 Feb;196(4):1922-32
Vago JP et al
2016/01/01
Application: In Vivo, Sample Type: In Vivo PubMed
  • No.: 1
  • 文献情報:
    Hermant B et al. Identification of proteases involved in the proteolysis of vascular endothelium cadherin during neutrophil transmigration. J. Biol. Chem. 2003 Apr;278(16):14002-12
    Hermant B et al
    2003/01/01
  • 備考:
    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 2
  • 文献情報:
    Hirche TO et al. Deficiency in neutrophil elastase does not impair neutrophil recruitment to inflamed sites. Am. J. Respir. Cell Mol. Biol. 2004 Apr;30(4):576-84
    Hirche TO et al
    2004/01/01
  • 備考:
    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 3
  • 文献情報:
    Tam EM et al. Membrane protease proteomics: Isotope-coded affinity tag MS identification of undescribed MT1-matrix metalloproteinase substrates. Proc. Natl. Acad. Sci. U.S.A. 2004 May;101(18):6917-22
    Tam EM et al
    2004/01/01
  • 備考:
    Application: Enzyme Activity, Sample Type: Cell Supernates
  • 参照:
    PubMed
  • No.: 4
  • 文献情報:
    Cortesio CL et al. Mannan-binding lectin-associated serine protease 3 cleaves synthetic peptides and insulin-like growth factor-binding protein 5. Arch. Biochem. Biophys. 2006 May;449(1-2):164-70
    Cortesio CL et al
    2006/01/01
  • 備考:
    Application: Enzyme Activity, Sample type: D10 affinity-matured variant of hVbeta2
  • 参照:
    PubMed
  • No.: 5
  • 文献情報:
    Into T et al. Arginine-specific gingipains from Porphyromonas gingivalis deprive protective functions of secretory leucocyte protease inhibitor in periodontal tissue. Clin. Exp. Immunol. 2006 Sep;145(3):545-54
    Into T et al
    2006/01/01
  • 備考:
    Species: Human, Application: Activity Assay, Sample type: Whole Cells
  • 参照:
    PubMed
  • No.: 6
  • 文献情報:
    Xu W et al. Epithelial cells trigger frontline immunoglobulin class switching through a pathway regulated by the inhibitor SLPI. Nat. Immunol. 2007 Mar;8(3):294-303
    Xu W et al
    2007/01/01
  • 備考:
    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 7
  • 文献情報:
    Niemann CU et al. Neutrophil elastase depends on serglycin proteoglycan for localization in granules. Blood 2007 May;109(10):4478-86
    Niemann CU et al
    2007/01/01
  • 備考:
    Species: Mouse, Application: Enzyme Activity, Sample type: Cell Lysates
  • 参照:
    PubMed
  • No.: 8
  • 文献情報:
    Fernie-King BA et al. Streptococcal DRS (distantly related to SIC) and SIC inhibit antimicrobial peptides, components of mucosal innate immunity: a comparison of their activities. Microbes Infect. 2007 Mar;9(3):300-7
    Fernie-King BA et al
    2007/01/01
  • 備考:
    Species: Bacteria, Application: Bioassay, Sample type: Whole Cells
  • 参照:
    PubMed
  • No.: 9
  • 文献情報:
    Sugino T et al. The secretory leukocyte protease inhibitor (SLPI) suppresses cancer cell invasion but promotes blood-borne metastasis via an invasion-independent pathway. J. Pathol. 2007 Jun;212(2):152-60
    Sugino T et al
    2007/01/01
  • 備考:
    Species: Mouse, Application: Bioassay, Sample type: Whole Cells
  • 参照:
    PubMed
  • No.: 10
  • 文献情報:
    Simpkins FA et al. The alarm anti-protease, secretory leukocyte protease inhibitor, is a proliferation and survival factor for ovarian cancer cells. Carcinogenesis 2008 Mar;29(3):466-72
    Simpkins FA et al
    2008/01/01
  • 備考:
    Species: Human, Application: Western Blot, Cell Lysates
  • 参照:
    PubMed
  • No.: 11
  • 文献情報:
    Jacobsen LC et al. The secretory leukocyte protease inhibitor (SLPI) and the secondary granule protein lactoferrin are synthesized in myelocytes, colocalize in subcellular fractions of neutrophils, and are coreleased by activated neutrophils. J. Leukoc. B
    Jacobsen LC et al
    2008/01/01
  • 備考:
    Application: Western Blot Control
  • 参照:
    PubMed
  • No.: 12
  • 文献情報:
    Nicol GR et al. Use of an immunoaffinity-mass spectrometry-based approach for the quantification of protein biomarkers from serum samples of lung cancer patients. Mol. Cell Proteomics 2008 Oct;7(10):1974-82
    Nicol GR et al
    2008/01/01
  • 備考:
    Application: Other: See notes, Sample Type: Buffer
  • 参照:
    PubMed
  • No.: 13
  • 文献情報:
    Seto T et al. SLPI prevents cytokine release in mite protease-exposed conjunctival epithelial cells. Biochem. Biophys. Res. Commun. 2009 Feb;379(3):681-5
    Seto T et al
    2009/01/01
  • 備考:
    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 14
  • 文献情報:
    Rasool N et al. Secretory leukocyte protease inhibitor antagonizes paclitaxel in ovarian cancer cells. Clin. Cancer Res. 2010 Jan;16(2):600-9
    Rasool N et al
    2010/01/01
  • 備考:
    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 15
  • 文献情報:
    Vega-Carrascal I et al. Dysregulation of TIM-3-galectin-9 pathway in the cystic fibrosis airways. J. Immunol. 2011 Mar;186(5):2897-909
    Vega-Carrascal I et al
    2011/01/01
  • 備考:
    Application: Bioassay, Sample Type: BALF
  • 参照:
    PubMed
  • No.: 16
  • 文献情報:
    M端ller AM et al. Inhibition of SLPI ameliorates disease activity in experimental autoimmune encephalomyelitis. BMC Neurosci 2012;13:30
    M端ller AM et al
    2012/01/01
  • 備考:
    Application: Bioassay,ELISA capture,In Vivo, Sample Type: In Vivo,Serum,Whole Cells
  • 参照:
    PubMed
  • No.: 17
  • 文献情報:
    Suh HS et al. Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12). PLoS ONE 2012;7(4):e35115
    Suh HS et al
    2012/01/01
  • 備考:
    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 18
  • 文献情報:
    Hannila SS et al. Secretory leukocyte protease inhibitor reverses inhibition by CNS myelin, promotes regeneration in the optic nerve, and suppresses expression of the transforming growth factor-&#x3B2; signaling protein Smad2. J. Neurosci. 2013 Mar;33(12)
    Hannila SS et al
    2013/01/01
  • 備考:
    Application: Bioassay,In Vivo, Sample Type: Whole Cells,Whole Organism
  • 参照:
    PubMed
  • No.: 19
  • 文献情報:
    Labidi-Galy SI et al. Elafin drives poor outcome in high-grade serous ovarian cancers and basal-like breast tumors. Oncogene 2015 Jan;34(3):373-83
    Labidi-Galy SI et al
    2015/01/01
  • 備考:
    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 20
  • 文献情報:
    Yang Y et al. Quantitative proteomic analysis of oral brush biopsies identifies secretory leukocyte protease inhibitor as a promising, mechanism-based oral cancer biomarker. PLoS ONE 2014;9(4):e95389
    Yang Y et al
    2014/01/01
  • 備考:
    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 21
  • 文献情報:
    Stapels DA et al. Staphylococcus aureus secretes a unique class of neutrophil serine protease inhibitors. Proc. Natl. Acad. Sci. U.S.A. 2014 Sep;111(36):13187-92
    Stapels DA et al
    2014/01/01
  • 備考:
    Application: Inhibitor, Sample Type: Protease in buffer
  • 参照:
    PubMed
  • No.: 22
  • 文献情報:
    Woodham AW et al. Inhibition of Langerhans cell maturation by human papillomavirus type 16: a novel role for the annexin A2 heterotetramer in immune suppression. J. Immunol. 2014 May;192(10):4748-57
    Woodham AW et al
    2014/01/01
  • 備考:
    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 23
  • 文献情報:
    Vago JP et al. Proresolving Actions of Synthetic and Natural Protease Inhibitors Are Mediated by Annexin A1. J. Immunol. 2016 Feb;196(4):1922-32
    Vago JP et al
    2016/01/01
  • 備考:
    Application: In Vivo, Sample Type: In Vivo
  • 参照:
    PubMed