ADAM10, Human, Recombinant, Carrier-free

データシート

• 商品コード：936-AD-020
• メーカー：RSD
• 包装：20μg
• 価格： ¥125,000
• 在庫：無(未発注)

マイリストに追加 マイリストに追加済

• No.： 1
• 文献情報：
  Hinkle CL et al. Selective roles for tumor necrosis factor alpha-converting enzyme/ADAM17 in the shedding of the epidermal growth factor receptor ligand family: the juxtamembrane stalk determines cleavage efficiency. J. Biol. Chem. 2004 Jun;279(23):24179-
  Hinkle CL et al
  2004/01/01
  
• 備考：
  Application: Enzyme Activity, Sample Type: recombinant protein
• 参照：
  

• No.： 2
• 文献情報：
  Schulte M et al. ADAM10 regulates FasL cell surface expression and modulates FasL-induced cytotoxicity and activation-induced cell death. Cell Death Differ. 2007 May;14(5):1040-9
  Schulte M et al
  2007/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 3
• 文献情報：
  Fridman JS et al. Selective inhibition of ADAM metalloproteases as a novel approach for modulating ErbB pathways in cancer. Clin. Cancer Res. 2007 Mar;13(6):1892-902
  Fridman JS et al
  2007/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Peptide Substrate
• 参照：
  

• No.： 4
• 文献情報：
  Lemieux GA et al. The low affinity IgE receptor (CD23) is cleaved by the metalloproteinase ADAM10. J. Biol. Chem. 2007 May;282(20):14836-44
  Lemieux GA et al
  2007/01/01
  
• 備考：
  Application: Enzyme Activity, Sample type: D10 affinity-matured variant of hVbeta2
• 参照：
  

• No.： 5
• 文献情報：
  Moss ML et al. The ADAM10 prodomain is a specific inhibitor of ADAM10 proteolytic activity and inhibits cellular shedding events. J. Biol. Chem. 2007 Dec;282(49):35712-21
  Moss ML et al
  2007/01/01
  
• 備考：
  Species: Human, Application: Bioassay, Sample type: recombinant protein
• 参照：
  

• No.： 6
• 文献情報：
  Rapti M et al. The isolated N-terminal domains of TIMP-1 and TIMP-3 are insufficient for ADAM10 inhibition. Biochem. J. 2008 Apr;411(2):433-9
  Rapti M et al
  2008/01/01
  
• 備考：
  Application: Bioassay
• 参照：
  

• No.： 7
• 文献情報：
  Kohga K et al. Anticancer chemotherapy inhibits MHC class I-related chain a ectodomain shedding by downregulating ADAM10 expression in hepatocellular carcinoma. Cancer Res. 2009 Oct;69(20):8050-7
  Kohga K et al
  2009/01/01
  
• 備考：
  Application: Media Supplement - Cell Prep, Sample Type: Whole Tissue
• 参照：
  

• No.： 8
• 文献情報：
  Hayes CD et al. Striking reduction of amyloid plaque burden in an Alzheimer"s mouse model after chronic administration of carmustine. BMC Med 2013;11:81
  Hayes CD et al
  2013/01/01
  
• 備考：
  Application: inhibition, Sample Type: Whole Cells
• 参照：
  

• No.： 9
• 文献情報：
  McDonald AJ et al. A new paradigm for enzymatic control of α-cleavage and β-cleavage of the prion protein. J. Biol. Chem. 2014 Jan;289(2):803-13
  McDonald AJ et al
  2014/01/01
  
• 備考：
  Application: Enzyme Activity, Sample Type: Cell Lysates
• 参照：
  

• No.： 10
• 文献情報：
  Lajoie L et al. ADAM17-mediated shedding of FcγRIIIA on human NK cells: identification of the cleavage site and relationship with activation. J. Immunol. 2014 Jan;192(2):741-51
  Lajoie L et al
  2014/01/01
  
• 備考：
  Application: Bioassay, Sample Type: recombinant protein
• 参照：
  

• No.： 11
• 文献情報：
  Schlomann U et al. ADAM8 as a drug target in pancreatic cancer. Nat Commun 2015;6:6175
  Schlomann U et al
  2015/01/01
  
• 備考：
  Application: Bioassay, Sample Type: Whole Cells
• 参照：
  

• No.： 12
• 文献情報：
  Kl淡verpris S et al. Stanniocalcin-1 Potently Inhibits the Proteolytic Activity of the Metalloproteinase Pregnancy-associated Plasma Protein-A. J. Biol. Chem. 2015 Sep;290(36):21915-24
  Kl淡verpris S et al
  2015/01/01
  
• 備考：
  Application: Enzyme Assay, Sample Type: Proteins
• 参照：
  

• No.： 13
• 文献情報：
  テ〕varez-Fernテ。ndez SM et al. Serological immune response against ADAM10 pro-domain is associated with favourable prognosis in stage III colorectal cancer patients. Oncotarget 2016 Nov;7(48):80059-80076
  テ〕varez-Fernテ。ndez SM et al
  2016/01/01
  
• 備考：
  Application: Enzyme Activity, Sample Type: Serum
• 参照：
  

• No.： 14
• 文献情報：
  Parra LM et al. Growth factor and co-receptor release by structural regulation of substrate metalloprotease accessibility. Sci Rep 2016 Nov;6:37464
  Parra LM et al
  2016/01/01
  
• 備考：
  Application: Enzyme Assay, Sample Type: Proteins
• 参照：
  

• No.： 15
• 文献情報：
  Wong E et al. Harnessing the natural inhibitory domain to control TNFα Converting Enzyme (TACE) activity in vivo. Sci Rep 2016 Dec;6:35598
  Wong E et al
  2016/01/01
  
• 備考：
  Application: Enzyme Assay, Sample Type: Proteins
• 参照：
  

• No.： 16
• 文献情報：
  Conant K et al. Matrix metalloproteinase activity stimulates N-cadherin shedding and the soluble N-cadherin ectodomain promotes classical microglial activation. J Neuroinflammation 2017 Mar;14(1):56
  Conant K et al
  2017/01/01
  
• 備考：
  Application: Bioassay, Sample Type: recombinant protein
• 参照：