価格表

在庫・価格 : 2025年04月28日 17時18分 現在

商品名 商品コード メーカー 包装 価格 在庫 リスト
TGF-β1, Human, Recombinant <Transforming Growth Factor-β1>
データシート
240-B-002 RSDアールアンドディー システムズ
R&D Systems, Inc.
2 μg ¥64,000 3個以上 追加

在庫・価格 : 2025年04月28日 17時18分 現在

TGF-β1, Human, Recombinant <Transforming Growth Factor-β1>

  • 商品コード:240-B-002
  • メーカー:RSD
  • 包装:2μg
  • 価格: ¥64,000
  • 在庫:3個以上
使用文献
No. 文献情報 備考 参照
1 Lux A et al. Assignment of transforming growth factor beta1 and beta3 and a third new ligand to the type I receptor ALK-1. J. Biol. Chem. 1999 Apr;274(15):9984-92
Lux A et al
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Species: Human, Application: Bioassay, Sample type: Whole Cells PubMed
2 Mozes MM et al. Isoform specificity of commercially-available anti-TGF-beta antibodies. J. Immunol. Methods 1999 May;225(1-2):87-93
Mozes MM et al
1999/01/01
Application: Western Blot PubMed
3 Matsui S et al. Role of the endogenous prostaglandin E2 in human lung fibroblast interleukin-11 production. 1999 Sep;93(9):637-42
Matsui S et al
1999/01/01
Species: Human, Application: Bioassay, Whole Cells PubMed
4 Desfaits AC et al. Growth factors stimulate neointimal cells in vitro and increase the thickness of the neointima formed at the neck of porcine aneurysms treated by embolization. Stroke 2000 Feb;31(2):498-507
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Application: In Vivo PubMed
5 Farah IO et al. Repeated exposure induces periportal fibrosis in Schistosoma mansoni-infected baboons: role of TGF-beta and IL-4. J. Immunol. 2000 May;164(10):5337-43
Farah IO et al
2000/01/01
Application: ELISA Standard, Sample Type: Cell Supernates PubMed
6 Kenagy RD et al. Blockade of smooth muscle cell migration and proliferation in baboon aortic explants by interleukin-1beta and tumor necrosis factor-alpha is nitric oxide-dependent and nitric oxide-independent. J. Vasc. Res. ;37(5):381-9
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Application: Bioassay, Sample Type: N/A PubMed
7 Zeisberg M et al. Renal fibrosis: collagen composition and assembly regulates epithelial-mesenchymal transdifferentiation. Am. J. Pathol. 2001 Oct;159(4):1313-21
Zeisberg M et al
2001/01/01
Species: Mouse, Application: Bioassay, Sample type: Whole Cells PubMed
8 Vi単als F et al. Transforming growth factor beta1 (TGF-beta1) promotes endothelial cell survival during in vitro angiogenesis via an autocrine mechanism implicating TGF-alpha signaling. Mol. Cell. Biol. 2001 Nov;21(21):7218-30
Vi単als F et al
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Application: Bioassay, Sample Type: Whole Cells PubMed
9 Ikuno Y et al. TGFbeta1-dependent contraction of fibroblasts is mediated by the PDGFalpha receptor. Invest. Ophthalmol. Vis. Sci. 2002 Jan;43(1):41-6
Ikuno Y et al
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Species: Mouse, Application: Bioassay, Sample type: Whole Cells PubMed
10 Cashman J et al. Stromal-derived factor 1 inhibits the cycling of very primitive human hematopoietic cells in vitro and in NOD/SCID mice. Blood 2002 Feb;99(3):792-9
Cashman J et al
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Application: Bioassay, Sample Type: Whole Cells PubMed
11 Jardine H et al. Molecular mechanism of transforming growth factor (TGF)-beta1-induced glutathione depletion in alveolar epithelial cells. Involvement of AP-1/ARE and Fra-1. J. Biol. Chem. 2002 Jun;277(24):21158-66
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Application: Bioassay, Sample Type: Whole Cells PubMed
12 Liu X et al. Th2 cytokine regulation of type I collagen gel contraction mediated by human lung mesenchymal cells. Am. J. Physiol. Lung Cell Mol. Physiol. 2002 May;282(5):L1049-56
Liu X et al
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Application: ELISA Standard, Sample Type: Cell Supernates PubMed
13 Kakonen SM et al. Transforming growth factor-beta stimulates parathyroid hormone-related protein and osteolytic metastases via Smad and mitogen-activated protein kinase signaling pathways. J. Biol. Chem. 2002 Jul;277(27):24571-8
Kakonen SM et al
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Application: Bioassay, Sample Type: Whole Cells PubMed
14 Cheon H et al. Increased expression of pro-inflammatory cytokines and metalloproteinase-1 by TGF-beta1 in synovial fibroblasts from rheumatoid arthritis and normal individuals. Clin. Exp. Immunol. 2002 Mar;127(3):547-52
Cheon H et al
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Species: Human, Application: Bioassay, Sample type: Whole Cells PubMed
15 Banas B et al. Roles of SLC/CCL21 and CCR7 in human kidney for mesangial proliferation, migration, apoptosis, and tissue homeostasis. J. Immunol. 2002 May;168(9):4301-7
Banas B et al
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16 Sombroek CC et al. Prostanoids play a major role in the primary tumor-induced inhibition of dendritic cell differentiation. J. Immunol. 2002 May;168(9):4333-43
Sombroek CC et al
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Application: ELISA Standard PubMed
17 Liang CL et al. Epstein-Barr virus BZLF1 gene is activated by transforming growth factor-beta through cooperativity of Smads and c-Jun/c-Fos proteins. J. Biol. Chem. 2002 Jun;277(26):23345-57
Liang CL et al
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Application: Bioassay PubMed
18 Schmidt A et al. Induction of a hypertrophic growth status of coronary smooth muscle cells is associated with an overexpression of TGF-beta. Eur. J. Cell Biol. 2002 Mar;81(3):138-44
Schmidt A et al
2002/01/01
Species: Bovine, Application: Bioassay, Sample type: Whole Cells PubMed
19 Yan YT et al. Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway. Mol. Cell. Biol. 2002 Jul;22(13):4439-49
Yan YT et al
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Application: Bioassay, Sample Type: Whole Cells PubMed
20 Hagimoto N et al. TGF-beta 1 as an enhancer of Fas-mediated apoptosis of lung epithelial cells. J. Immunol. 2002 Jun;168(12):6470-8
Hagimoto N et al
2002/01/01
Application: Bioassay,In Vivo, Sample Type: Whole Cells PubMed
21 Ewan KB et al. Latent transforming growth factor-beta activation in mammary gland: regulation by ovarian hormones affects ductal and alveolar proliferation. Am. J. Pathol. 2002 Jun;160(6):2081-93
Ewan KB et al
2002/01/01
Species: Mink, Application: Bioassay, Sample type: Whole Cells PubMed
22 Rosado E et al. Transforming growth factor-beta1 regulation of growth zone chondrocytes is mediated by multiple interacting pathways. Biochim. Biophys. Acta 2002 Jun;1590(1-3):1-15
Rosado E et al
2002/01/01
Species: Rat, Application: Bioassay, Sample type: Whole Cells PubMed
23 Scharstuhl A et al. Inhibition of endogenous TGF-beta during experimental osteoarthritis prevents osteophyte formation and impairs cartilage repair. J. Immunol. 2002 Jul;169(1):507-14
Scharstuhl A et al
2002/01/01
Application: ELISA Standard PubMed
24 Neidert MR et al. Enhanced fibrin remodeling in vitro with TGF-beta1, insulin and plasmin for improved tissue-equivalents. Biomaterials 2002 Sep;23(17):3717-31
Neidert MR et al
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Application: Bioassay PubMed
25 Koh KR et al. Differential effects of fibroblast growth factor-4, epidermal growth factor and transforming growth factor-beta1 on functional development of stromal layers in acute myeloid leukemia. Leuk. Res. 2002 Oct;26(10):933-8
Koh KR et al
2002/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
26 Bauer BS et al. Latent and active transforming growth factor beta1 released from genetically modified keratinocytes modulates extracellular matrix expression by dermal fibroblasts in a coculture system. J. Invest. Dermatol. 2002 Aug;119(2):456-63
Bauer BS et al
2002/01/01
Application: ELISA Standard, Sample Type: Cell Supernates PubMed
27 Zhao W et al. Suppression of in vivo tumorigenicity of rat hepatoma cell line KDH-8 cells by soluble TGF-beta receptor type II. Cancer Immunol. Immunother. 2002 Sep;51(7):381-8
Zhao W et al
2002/01/01
Species: Rat, Application: Bioassay, Sample type: Whole Cells PubMed
28 Huaux F et al. A profibrotic function of IL-12p40 in experimental pulmonary fibrosis. J. Immunol. 2002 Sep;169(5):2653-61
Huaux F et al
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Application: Bioassay, Sample Type: Whole Cells PubMed
29 Wadhwa M et al. Cytokine levels as performance indicators for white blood cell reduction of platelet concentrates. Vox Sang. 2002 Aug;83(2):125-36
Wadhwa M et al
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Application: ELISA Standard, Sample Type: Whole Cells PubMed
30 Santoso S et al. The junctional adhesion molecule 3 (JAM-3) on human platelets is a counterreceptor for the leukocyte integrin Mac-1. J. Exp. Med. 2002 Sep;196(5):679-91
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Application: Bioassay, Sample Type: Whole Cells PubMed
31 Beaulieu S et al. Expression of a functional eotaxin (CC chemokine ligand 11) receptor CCR3 by human dendritic cells. J. Immunol. 2002 Sep;169(6):2925-36
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Species: Human, Application: Bioassay, Sample type: Whole Cells PubMed
32 Barton LF et al. Regulation of immunoproteasome subunit expression in vivo following pathogenic fungal infection. J. Immunol. 2002 Sep;169(6):3046-52
Barton LF et al
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Application: Bioassay, Sample Type: Whole Cells PubMed
33 Rutella S et al. Role for granulocyte colony-stimulating factor in the generation of human T regulatory type 1 cells. Blood 2002 Oct;100(7):2562-71
Rutella S et al
2002/01/01
Species: Human, Application: Bioassay, Sample type: Whole Cells PubMed
34 Enzmann V et al. Influence of interleukin 10 and transforming growth factor-beta on T cell stimulation through allogeneic retinal pigment epithelium cells in vitro. Ophthalmic Res. ;34(4):232-40
Enzmann V et al
Application: Bioassay, Sample Type: Whole Cells PubMed
35 Bendre MS et al. Expression of interleukin 8 and not parathyroid hormone-related protein by human breast cancer cells correlates with bone metastasis in vivo. Cancer Res. 2002 Oct;62(19):5571-9
Bendre MS et al
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Species: Human, Application: Bioassay, Sample type: Whole Cells PubMed
36 Tavassoli M et al. Tamoxifen inhibits the growth of head and neck cancer cells and sensitizes these cells to cisplatin induced-apoptosis: role of TGF-beta1. Carcinogenesis 2002 Oct;23(10):1569-75
Tavassoli M et al
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Application: Bioassay, Sample Type: Whole Cells PubMed
37 Seoane J et al. Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage. Nature 2002 Oct;419(6908):729-34
Seoane J et al
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Application: Bioassay, Sample Type: Whole Cells PubMed
38 Ishisaki A et al. Human umbilical vein endothelium-derived cells retain potential to differentiate into smooth muscle-like cells. J. Biol. Chem. 2003 Jan;278(2):1303-9
Ishisaki A et al
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Application: Bioassay, Sample Type: Whole Cells PubMed
39 Scharstuhl A et al. Loss of transforming growth factor counteraction on interleukin 1 mediated effects in cartilage of old mice. Ann. Rheum. Dis. 2002 Dec;61(12):1095-8
Scharstuhl A et al
2002/01/01
Species: Mouse, Application: In Vivo PubMed
40 Liu C et al. Smads 2 and 3 are differentially activated by transforming growth factor-beta (TGF-beta ) in quiescent and activated hepatic stellate cells. Constitutive nuclear localization of Smads in activated cells is TGF-beta-independent. J. Biol. Chem.
Liu C et al
2003/01/01
Species: Rat, Application: Bioassay, Sample type: Whole Cells PubMed
41 Huaux F et al. Dual roles of IL-4 in lung injury and fibrosis. J. Immunol. 2003 Feb;170(4):2083-92
Huaux F et al
2003/01/01
Sample Type: Whole Cells PubMed
42 Benckert C et al. Transforming growth factor beta 1 stimulates vascular endothelial growth factor gene transcription in human cholangiocellular carcinoma cells. Cancer Res. 2003 Mar;63(5):1083-92
Benckert C et al
2003/01/01
Species: Human, Application: Bioassay, Sample type: Whole Cells PubMed
43 Ashcroft GS et al. Estrogen modulates cutaneous wound healing by downregulating macrophage migration inhibitory factor. J. Clin. Invest. 2003 May;111(9):1309-18
Ashcroft GS et al
2003/01/01
Application: In Vivo PubMed
44 Hanna J et al. CXCL12 expression by invasive trophoblasts induces the specific migration of CD16- human natural killer cells. Blood 2003 Sep;102(5):1569-77
Hanna J et al
2003/01/01
Species: Human, Application: Bioassay, Sample type: Whole Cells PubMed
45 Luckhart S et al. Mammalian transforming growth factor beta1 activated after ingestion by Anopheles stephensi modulates mosquito immunity. Infect. Immun. 2003 Jun;71(6):3000-9
Luckhart S et al
2003/01/01
Application: Western Blot PubMed
46 Giusti C et al. Transforming growth factor beta-1 and amphiregulin act in synergy to increase the production of urokinase-type plasminogen activator in transformed breast epithelial cells. Int. J. Cancer 2003 Jul;105(6):769-78
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47 Levenberg S et al. Differentiation of human embryonic stem cells on three-dimensional polymer scaffolds. Proc. Natl. Acad. Sci. U.S.A. 2003 Oct;100(22):12741-6
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Species: Human, Application: Bioassay, Sample type: Whole Cells PubMed
48 Matsuyama S et al. SB-431542 and Gleevec inhibit transforming growth factor-beta-induced proliferation of human osteosarcoma cells. Cancer Res. 2003 Nov;63(22):7791-8
Matsuyama S et al
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Application: Bioassay, Sample Type: Whole Cells PubMed
49 Hardie WD et al. Conditional expression of transforming growth factor-alpha in adult mouse lung causes pulmonary fibrosis. Am. J. Physiol. Lung Cell Mol. Physiol. 2004 Apr;286(4):L741-9
Hardie WD et al
2004/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
50 Sekiya T et al. Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells. J. Biol. Chem. 2004 Feb;279(8):6840-6
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Species: Human, Application: Bioassay, Sample type: Whole Cells PubMed
51 Holland TA et al. Transforming growth factor-beta 1 release from oligo(poly(ethylene glycol) fumarate) hydrogels in conditions that model the cartilage wound healing environment. J Control Release 2004 Jan;94(1):101-14
Holland TA et al
2004/01/01
Application: Microparticle Release, Sample Type: Gelatin Microparticles PubMed
52 Calle Y et al. WASp deficiency in mice results in failure to form osteoclast sealing zones and defects in bone resorption. Blood 2004 May;103(9):3552-61
Calle Y et al
2004/01/01
Application: Bioassay PubMed
53 Leach RE et al. Heparin-binding EGF-like growth factor regulates human extravillous cytotrophoblast development during conversion to the invasive phenotype. Dev. Biol. 2004 Feb;266(2):223-37
Leach RE et al
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Application: Bioassay, Sample Type: Whole Cells PubMed
54 S叩nchez-Elsner T et al. A cross-talk between hypoxia and TGF-beta orchestrates erythropoietin gene regulation through SP1 and Smads. J. Mol. Biol. 2004 Feb;336(1):9-24
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55 Robertson H et al. Chronic renal allograft dysfunction: the role of T cell-mediated tubular epithelial to mesenchymal cell transition. J. Am. Soc. Nephrol. 2004 Feb;15(2):390-7
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56 Nishishita T et al. Angiopoietin 1, PDGF-B, and TGF-beta gene regulation in endothelial cell and smooth muscle cell interaction. J. Cell. Biochem. 2004 Feb;91(3):584-93
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2004/01/01
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57 Takahashi M et al. Immature dendritic cells reduce proinflammatory cytokine production by a coculture of macrophages and apoptotic cells in a cell-to-cell contact-dependent manner. J. Leukoc. Biol. 2004 May;75(5):865-73
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58 Bhowmick NA et al. TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia. Science 2004 Feb;303(5659):848-51
Bhowmick NA et al
2004/01/01
Application: Binding Assay, Sample Type: Cell Lysates PubMed
59 R鱈os R et al. Differential response to exogenous and endogenous myostatin in myoblasts suggests that myostatin acts as an autocrine factor in vivo. Endocrinology 2004 Jun;145(6):2795-803
R鱈os R et al
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60 Studer RK et al. Chondrocyte response to growth factors is modulated by p38 mitogen-activated protein kinase inhibition. Arthritis Res. Ther. 2004;6(1):R56-R64
Studer RK et al
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61 Chen C et al. Two modes by which Lefty proteins inhibit nodal signaling. Curr. Biol. 2004 Apr;14(7):618-24
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62 Conley BA et al. Endoglin controls cell migration and composition of focal adhesions: function of the cytosolic domain. J. Biol. Chem. 2004 Jun;279(26):27440-9
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63 Zheng SG et al. Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10. J. Immunol. 2004 May;172(9):5213-21
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2004/01/01
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64 Torrealba JR et al. Metastable tolerance to rhesus monkey renal transplants is correlated with allograft TGF-beta 1+CD4+ T regulatory cell infiltrates. J. Immunol. 2004 May;172(9):5753-64
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Application: Western Blot PubMed
65 Bechara RI et al. Transforming growth factor beta1 expression and activation is increased in the alcoholic rat lung. Am. J. Respir. Crit. Care Med. 2004 Jul;170(2):188-94
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2004/01/01
Application: Bioassay, Sample Type: Cell Lysates PubMed
66 Cosgrove GP et al. Pigment epithelium-derived factor in idiopathic pulmonary fibrosis: a role in aberrant angiogenesis. Am. J. Respir. Crit. Care Med. 2004 Aug;170(3):242-51
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67 Barksdale AR et al. Regulation of arginase expression by T-helper II cytokines and isoproterenol. Surgery 2004 May;135(5):527-35
Barksdale AR et al
2004/01/01
Species: Mouse, Application: Bioassay, Sample type: Whole Cells PubMed
68 Wildemann B et al. Local delivery of growth factors from coated titanium plates increases osteotomy healing in rats. Bone 2004 May;34(5):862-8
Wildemann B et al
2004/01/01
Application: In Vivo, Sample Type: Bone Implant PubMed
69 Pociask DA et al. Asbestos-derived reactive oxygen species activate TGF-beta1. Lab. Invest. 2004 Aug;84(8):1013-23
Pociask DA et al
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Application: Bioassay PubMed
70 Huang SS et al. Cellular growth inhibition by TGF-beta1 involves IRS proteins. FEBS Lett. 2004 May;565(1-3):117-21
Huang SS et al
2004/01/01
Species: Mink, Application: Bioassay, Sample type: Whole Cells PubMed
71 Karst M et al. Roles of stromal cell RANKL, OPG, and M-CSF expression in biphasic TGF-beta regulation of osteoclast differentiation. J. Cell. Physiol. 2004 Jul;200(1):99-106
Karst M et al
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72 Bosnakovski D et al. Chondrogenic differentiation of bovine bone marrow mesenchymal stem cells in pellet cultural system. Exp. Hematol. 2004 May;32(5):502-9
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73 Eriksson M et al. Unique phenotype of human uterine NK cells and their regulation by endogenous TGF-beta. J. Leukoc. Biol. 2004 Sep;76(3):667-75
Eriksson M et al
2004/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
74 Zhu X et al. Myostatin signaling through Smad2, Smad3 and Smad4 is regulated by the inhibitory Smad7 by a negative feedback mechanism. Cytokine 2004 Jun;26(6):262-72
Zhu X et al
2004/01/01
Species: Human, Application: Bioassay, Sample type: Whole Cells PubMed
75 Phillips TM. Rapid analysis of inflammatory cytokines in cerebrospinal fluid using chip-based immunoaffinity electrophoresis. Electrophoresis 2004 Jun;25(10-11):1652-9
Phillips TM
2004/01/01
Application: ChIP Standard PubMed
76 Pratsinis H et al. Differential proliferative response of fetal and adult human skin fibroblasts to transforming growth factor-beta. Wound Repair Regen ;12(3):374-83
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77 Kawai T et al. Efficient cardiomyogenic differentiation of embryonic stem cell by fibroblast growth factor 2 and bone morphogenetic protein 2. Circ. J. 2004 Jul;68(7):691-702
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2004/01/01
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78 Wildemann B et al. Quantification, localization, and expression of IGF-I and TGF-beta1 during growth factor-stimulated fracture healing. Calcif. Tissue Int. 2004 Apr;74(4):388-97
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79 Faucheux C et al. Recapitulation of the parathyroid hormone-related peptide-Indian hedgehog pathway in the regenerating deer antler. Dev. Dyn. 2004 Sep;231(1):88-97
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2004/01/01
Species: Deer - Cervus elaphus, Application: Bioassay, Sample type: Whole Cells PubMed
80 Wolk K et al. IL-22 increases the innate immunity of tissues. Immunity 2004 Aug;21(2):241-54
Wolk K et al
2004/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
81 Ogawa N et al. Expression of interferon-inducible T cell alpha chemoattractant (CXCL11) in the salivary glands of patients with Sjテθ津つカgren&#39;s syndrome. Clin. Immunol. 2004 Sep;112(3):235-8
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2004/01/01
Species: Human, Application: Bioassay, Whole Cells PubMed
82 Tardif G et al. Differential gene expression and regulation of the bone morphogenetic protein antagonists follistatin and gremlin in normal and osteoarthritic human chondrocytes and synovial fibroblasts. Arthritis Rheum. 2004 Aug;50(8):2521-30
Tardif G et al
2004/01/01
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83 Fu S et al. TGF-beta induces Foxp3 + T-regulatory cells from CD4 + CD25 - precursors. Am. J. Transplant. 2004 Oct;4(10):1614-27
Fu S et al
2004/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
84 Nagineni CN et al. Expression of PDGF and their receptors in human retinal pigment epithelial cells and fibroblasts: regulation by TGF-beta. J. Cell. Physiol. 2005 Apr;203(1):35-43
Nagineni CN et al
2005/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
85 Allam JP et al. Transforming growth factor-beta1 regulates the expression of the high-affinity receptor for IgE on CD34 stem cell-derived CD1a dendritic cells in vitro. J. Invest. Dermatol. 2004 Oct;123(4):676-82
Allam JP et al
2004/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
86 Maire M et al. Retention of transforming growth factor beta1 using functionalized dextran-based hydrogels. Biomaterials 2005 May;26(14):1771-80
Maire M et al
2005/01/01
Application: ELISA Standard,Loaded into hydrogels PubMed
87 Kettunen P et al. Coordination of trigeminal axon navigation and patterning with tooth organ formation: epithelial-mesenchymal interactions, and epithelial Wnt4 and Tgfbeta1 regulate semaphorin 3a expression in the dental mesenchyme. Development 2005 Jan;
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2005/01/01
Application: Bioassay, Sample Type: Whole Tissue PubMed
88 Muraoka-Cook RS et al. Conditional overexpression of active transforming growth factor beta1 in vivo accelerates metastases of transgenic mammary tumors. Cancer Res. 2004 Dec;64(24):9002-11
Muraoka-Cook RS et al
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Application: Bioassay, Sample Type: Whole Cells PubMed
89 Castigli E et al. TACI and BAFF-R mediate isotype switching in B cells. J. Exp. Med. 2005 Jan;201(1):35-9
Castigli E et al
2005/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
90 Yuan J et al. Langerhans cells derived from genetically modified human CD34+ hemopoietic progenitors are more potent than peptide-pulsed Langerhans cells for inducing antigen-specific CD8+ cytolytic T lymphocyte responses. J. Immunol. 2005 Jan;174(2):758-
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91 Mespl竪s B et al. Neuronal TGF-beta1 mediates IL-9/mast cell interaction and exacerbates excitotoxicity in newborn mice. Neurobiol. Dis. 2005 Feb;18(1):193-205
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Application: In Vivo PubMed
92 Rao PE et al. Differentiation and expansion of T cells with regulatory function from human peripheral lymphocytes by stimulation in the presence of TGF-{beta}. J. Immunol. 2005 Feb;174(3):1446-55
Rao PE et al
2005/01/01
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93 Karl C et al. Neuronal precursor-specific activity of a human doublecortin regulatory sequence. J. Neurochem. 2005 Jan;92(2):264-82
Karl C et al
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94 Fujita H et al. Differential production of Th1- and Th2-type chemokines by mouse Langerhans cells and splenic dendritic cells. J. Invest. Dermatol. 2005 Feb;124(2):343-50
Fujita H et al
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Application: Bioassay, Sample Type: Whole Cells PubMed
95 Kanematsu A et al. Induction of smooth muscle cell-like phenotype in marrow-derived cells among regenerating urinary bladder smooth muscle cells. Am. J. Pathol. 2005 Feb;166(2):565-73
Kanematsu A et al
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Application: Bioassay, Sample Type: Cell Supernates PubMed
96 Lyakh LA et al. TGF-beta and vitamin D3 utilize distinct pathways to suppress IL-12 production and modulate rapid differentiation of human monocytes into CD83+ dendritic cells. J. Immunol. 2005 Feb;174(4):2061-70
Lyakh LA et al
2005/01/01
Species: Human, Application: Bioassay, Sample type: Whole Cells PubMed
97 Ogden CA et al. Enhanced apoptotic cell clearance capacity and B cell survival factor production by IL-10-activated macrophages: implications for Burkitt&#39;s lymphoma. J. Immunol. 2005 Mar;174(5):3015-23
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98 Dulos J et al. CYP7B expression and activity in fibroblast-like synoviocytes from patients with rheumatoid arthritis: regulation by proinflammatory cytokines. Arthritis Rheum. 2005 Mar;52(3):770-8
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Application: Bioassay, Sample Type: Whole Cells PubMed
99 Distler JH et al. Expression of interleukin-21 receptor in epidermis from patients with systemic sclerosis. Arthritis Rheum. 2005 Mar;52(3):856-64
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Application: Bioassay, Sample Type: Whole Cells PubMed
100 Shiraki N et al. TGF-beta signaling potentiates differentiation of embryonic stem cells to Pdx-1 expressing endodermal cells. Genes Cells 2005 Jun;10(6):503-16
Shiraki N et al
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101 Wang L et al. Activation of transforming growth factor-beta1/p38/Smad3 signaling in stromal cells requires reactive oxygen species-mediated MMP-2 activity during bone marrow damage. Stem Cells 2005 Sep;23(8):1122-34
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2005/01/01
Species: Human, Mouse, Application: Bioassay, Sample type: Whole Cells PubMed
102 Jung Y et al. Regulation of SDF-1 (CXCL12) production by osteoblasts; a possible mechanism for stem cell homing. Bone 2006 Apr;38(4):497-508
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418 Komatsu N et al. Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis. Nat. Med. 2014 Jan;20(1):62-8
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419 Gong JH et al. Inhibition of airway epithelial-to-mesenchymal transition and fibrosis by kaempferol in endotoxin-induced epithelial cells and ovalbumin-sensitized mice. Lab. Invest. 2014 Mar;94(3):297-308
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420 Leung L et al. Loss of canonical Smad4 signaling promotes KRAS driven malignant transformation of human pancreatic duct epithelial cells and metastasis. PLoS ONE 2013;8(12):e84366
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421 Roach KM et al. The K+ channel KCa3.1 as a novel target for idiopathic pulmonary fibrosis. PLoS ONE 2013;8(12):e85244
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422 Axpe E et al. Detection of atomic scale changes in the free volume void size of three-dimensional colorectal cancer cell culture using positron annihilation lifetime spectroscopy. PLoS ONE 2014;9(1):e83838
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423 Park SM et al. Musashi-2 controls cell fate, lineage bias, and TGF-&#x3B2; signaling in HSCs. J. Exp. Med. 2014 Jan;211(1):71-87
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424 Kim DS et al. Gene expression profiles of human adipose tissue-derived mesenchymal stem cells are modified by cell culture density. PLoS ONE 2014;9(1):e83363
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425 Chen X et al. Effective chemoimmunotherapy with anti-TGF&#x3B2; antibody and cyclophosphamide in a mouse model of breast cancer. PLoS ONE 2014;9(1):e85398
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426 Courtney DG et al. Development of allele-specific gene-silencing siRNAs for TGFBI Arg124Cys in lattice corneal dystrophy type I. Invest. Ophthalmol. Vis. Sci. 2014 Feb;55(2):977-85
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427 Ahmad T et al. Miro1 regulates intercellular mitochondrial transport &amp; enhances mesenchymal stem cell rescue efficacy. EMBO J. 2014 May;33(9):994-1010
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428 Miller MM et al. CD4+CD25+ T regulatory cells activated during feline immunodeficiency virus infection convert T helper cells into functional suppressors through a membrane-bound TGF&#x3B2; / GARP-mediated mechanism. Virol. J. 2014;11:7
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429 Wang X et al. Cystatin B is a progression marker of human epithelial ovarian tumors mediated by the TGF-&#x3B2; signaling pathway. Int. J. Oncol. 2014 Apr;44(4):1099-106
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430 Naji A et al. Binding of HLA-G to ITIM-bearing Ig-like transcript 2 receptor suppresses B cell responses. J. Immunol. 2014 Feb;192(4):1536-46
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431 Lee CG et al. MicroRNA-147 induces a mesenchymal-to-epithelial transition (MET) and reverses EGFR inhibitor resistance. PLoS ONE 2014;9(1):e84597
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432 Ratnayake M et al. Human chondrocytes respond discordantly to the protein encoded by the osteoarthritis susceptibility gene GDF5. PLoS ONE 2014;9(1):e86590
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433 Desai VD et al. Reversible modulation of myofibroblast differentiation in adipose-derived mesenchymal stem cells. PLoS ONE 2014;9(1):e86865
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434 Du L et al. Hypoxia enhances protective effect of placental-derived mesenchymal stem cells on damaged intestinal epithelial cells by promoting secretion of insulin-like growth factor-1. Int J Mol Sci 2014;15(2):1983-2002
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435 Mirkina I et al. Phenotyping of human melanoma cells reveals a unique composition of receptor targets and a subpopulation co-expressing ErbB4, EPO-R and NGF-R. PLoS ONE 2014;9(1):e84417
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436 Fu RG et al. Inhibition of the K+ channel K(Ca)3.1 reduces TGF-&#x3B2;1-induced premature senescence, myofibroblast phenotype transition and proliferation of mesangial cells. PLoS ONE 2014;9(1):e87410
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437 Italiani P et al. Transcriptomic profiling of the development of the inflammatory response in human monocytes in vitro. PLoS ONE 2014;9(2):e87680
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438 Lauden L et al. TGF-&#x3B2;-induced (TGFBI) protein in melanoma: a signature of high metastatic potential. J. Invest. Dermatol. 2014 Jun;134(6):1675-85
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439 Tannheimer SL et al. The in vitro pharmacology of GS-5759, a novel bifunctional phosphodiesterase 4 inhibitor and long acting &#x3B2;2-adrenoceptor agonist. J. Pharmacol. Exp. Ther. 2014 Apr;349(1):85-93
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440 Paganelli M et al. Downregulation of Sox9 expression associates with hepatogenic differentiation of human liver mesenchymal stem/progenitor cells. Stem Cells Dev. 2014 Jun;23(12):1377-91
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441 Prigent L et al. The aryl hydrocarbon receptor is functionally upregulated early in the course of human T-cell activation. Eur. J. Immunol. 2014 May;44(5):1330-40
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442 Diepenbruck M et al. Tead2 expression levels control the subcellular distribution of Yap and Taz, zyxin expression and epithelial-mesenchymal transition. J. Cell. Sci. 2014 Apr;127(Pt 7):1523-36
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443 Suresh Babu S et al. TGF&#x3B2;-mediated suppression of CD248 in non-cancer cells via canonical Smad-dependent signaling pathways is uncoupled in cancer cells. BMC Cancer 2014;14:113
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444 Liu RY et al. JAK/STAT3 signaling is required for TGF-&#x3B2;-induced epithelial-mesenchymal transition in lung cancer cells. Int. J. Oncol. 2014 May;44(5):1643-51
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445 Gao X et al. Bone morphogenetic protein signaling protects against cerulein-induced pancreatic fibrosis. PLoS ONE 2014;9(2):e89114
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446 Ifkovits JL et al. Inhibition of TGF&#x3B2; signaling increases direct conversion of fibroblasts to induced cardiomyocytes. PLoS ONE 2014;9(2):e89678
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447 Kudo-Saito C et al. Induction of immunoregulatory CD271+ cells by metastatic tumor cells that express human endogenous retrovirus H. Cancer Res. 2014 Mar;74(5):1361-70
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448 Borestr旦m C et al. Footprint-free human induced pluripotent stem cells from articular cartilage with redifferentiation capacity: a first step toward a clinical-grade cell source. Stem Cells Transl Med 2014 Apr;3(4):433-47
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449 Overstreet JM et al. Redox control of p53 in the transcriptional regulation of TGF-&#x3B2;1 target genes through SMAD cooperativity. Cell. Signal. 2014 Jul;26(7):1427-36
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450 Xu S et al. Loss of Dab2 expression in breast cancer cells impairs their ability to deplete TGF-&#x3B2; and induce Tregs development via TGF-&#x3B2;. PLoS ONE 2014;9(3):e91709
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451 Hiemer SE et al. The transcriptional regulators TAZ and YAP direct transforming growth factor &#x3B2;-induced tumorigenic phenotypes in breast cancer cells. J. Biol. Chem. 2014 May;289(19):13461-74
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452 Jeon KI et al. Inhibitory effects of PPAR&#x3B3; ligands on TGF-&#x3B2;1-induced corneal myofibroblast transformation. Am. J. Pathol. 2014 May;184(5):1429-45
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453 Aschner Y et al. Protein tyrosine phosphatase &#x3B1; mediates profibrotic signaling in lung fibroblasts through TGF-&#x3B2; responsiveness. Am. J. Pathol. 2014 May;184(5):1489-502
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454 Kim SI et al. TGF-&#x3B2;-activated kinase 1 is crucial in podocyte differentiation and glomerular capillary formation. J. Am. Soc. Nephrol. 2014 Sep;25(9):1966-78
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455 Miller CL et al. Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation. PLoS Genet. 2014 Mar;10(3):e1004263
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456 Yuki K et al. E-cadherin-downregulation and RECK-upregulation are coupled in the non-malignant epithelial cell line MCF10A but not in multiple carcinoma-derived cell lines. Sci Rep 2014;4:4568
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457 Echeverr鱈a C et al. Endotoxin induces fibrosis in vascular endothelial cells through a mechanism dependent on transient receptor protein melastatin 7 activity. PLoS ONE 2014;9(4):e94146
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458 Shi X et al. TGF-&#x3B2;/Smad3 stimulates stem cell/developmental gene expression and vascular smooth muscle cell de-differentiation. PLoS ONE 2014;9(4):e93995
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459 Wei DG et al. Histone deacetylase inhibitor romidepsin induces HIV expression in CD4 T cells from patients on suppressive antiretroviral therapy at concentrations achieved by clinical dosing. PLoS Pathog. 2014 Apr;10(4):e1004071
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460 Villegas VE et al. Identification of novel non-coding RNA-based negative feedback regulating the expression of the oncogenic transcription factor GLI1. Mol Oncol 2014 Jul;8(5):912-26
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461 Tulley S et al. Transcriptional regulation of seprase in invasive melanoma cells by transforming growth factor-&#x3B2; signaling. J. Biol. Chem. 2014 May;289(22):15280-96
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462 Kumawat K et al. TGF-&#x3B2;-activated kinase 1 (TAK1) signaling regulates TGF-&#x3B2;-induced WNT-5A expression in airway smooth muscle cells via Sp1 and &#x3B2;-catenin. PLoS ONE 2014;9(4):e94801
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463 Luo F et al. Arsenic trioxide inhibits transforming growth factor-&#x3B2;1-induced fibroblast to myofibroblast differentiation in vitro and bleomycin induced lung fibrosis in vivo. Respir. Res. 2014;15:51
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464 Kongsbak M et al. Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells. PLoS ONE 2014;9(5):e96695
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465 Kofler DM et al. Decreased RORC-dependent silencing of prostaglandin receptor EP2 induces autoimmune Th17 cells. J. Clin. Invest. 2014 Jun;124(6):2513-22
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466 Jakobsen RB et al. Analysis of the effects of five factors relevant to in vitro chondrogenesis of human mesenchymal stem cells using factorial design and high throughput mRNA-profiling. PLoS ONE 2014;9(5):e96615
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467 Kirkegaard T et al. The broad-spectrum metalloproteinase inhibitor BB-94 inhibits growth, HER3 and Erk activation in fulvestrant-resistant breast cancer cell lines. Int. J. Oncol. 2014 Jul;45(1):393-400
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468 Solomon JD et al. VDR activity is differentially affected by Hic-5 in prostate cancer and stromal cells. Mol. Cancer Res. 2014 Aug;12(8):1166-80
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469 Wiener Z et al. Oncogenic mutations in intestinal adenomas regulate Bim-mediated apoptosis induced by TGF-&#x3B2;. Proc. Natl. Acad. Sci. U.S.A. 2014 May;111(21):E2229-36
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470 Fehrholz M et al. Caffeine and rolipram affect Smad signalling and TGF-&#x3B2;1 stimulated CTGF and transgelin expression in lung epithelial cells. PLoS ONE 2014;9(5):e97357
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471 Desai LP et al. Negative regulation of NADPH oxidase 4 by hydrogen peroxide-inducible clone 5 (Hic-5) protein. J. Biol. Chem. 2014 Jun;289(26):18270-8
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472 Choi SH et al. Synthetic triterpenoid induces 15-PGDH expression and suppresses inflammation-driven colon carcinogenesis. J. Clin. Invest. 2014 Jun;124(6):2472-82
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473 Matthews AJ et al. Binding of AID to DNA does not correlate with mutator activity. J. Immunol. 2014 Jul;193(1):252-7
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474 Salvo E et al. Combined targeting of TGF-&#x3B2;1 and integrin &#x3B2;3 impairs lymph node metastasis in a mouse model of non-small-cell lung cancer. Mol. Cancer 2014;13:112
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475 Togashi Y et al. Homozygous deletion of the activin A receptor, type IB gene is associated with an aggressive cancer phenotype in pancreatic cancer. Mol. Cancer 2014;13:126
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476 Liu Y et al. Inhibition by all-trans-retinoic acid of transforming growth factor-&#x3B2;-induced collagen gel contraction mediated by human tenon fibroblasts. Invest. Ophthalmol. Vis. Sci. 2014 Jul;55(7):4199-205
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477 Santhekadur PK et al. Staphylococcal nuclease domain containing-1 (SND1) promotes migration and invasion via angiotensin II type 1 receptor (AT1R) and TGF&#x3B2; signaling. FEBS Open Bio 2014;4:353-61
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478 Zhao C et al. Cellular stress amplifies TLR3/4-induced CXCL1/2 gene transcription in mononuclear phagocytes via RIPK1. J. Immunol. 2014 Jul;193(2):879-88
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479 Arts MR et al. Systemic sclerosis immunoglobulin induces growth and a pro-fibrotic state in vascular smooth muscle cells through the epidermal growth factor receptor. PLoS ONE 2014;9(6):e100035
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480 Lim MJ et al. Induction of galectin-1 by TGF-&#x3B2;1 accelerates fibrosis through enhancing nuclear retention of Smad2. Exp. Cell Res. 2014 Aug;326(1):125-35
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481 Lee HS et al. Standardized Salvia miltiorrhiza extract suppresses hepatic stellate cell activation and attenuates steatohepatitis induced by a methionine-choline deficient diet in mice. Molecules 2014;19(6):8189-211
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482 Hardin H et al. The roles of the epithelial-mesenchymal transition marker PRRX1 and miR-146b-5p in papillary thyroid carcinoma progression. Am. J. Pathol. 2014 Aug;184(8):2342-54
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483 Mercer F et al. Differentiation of IL-17-producing effector and regulatory human T cells from lineage-committed naive precursors. J. Immunol. 2014 Aug;193(3):1047-54
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484 Kogiso T et al. Efficient induction of apoptosis by wee1 kinase inhibition in hepatocellular carcinoma cells. PLoS ONE 2014;9(6):e100495
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485 Mar巽ais A et al. The metabolic checkpoint kinase mTOR is essential for IL-15 signaling during the development and activation of NK cells. Nat. Immunol. 2014 Aug;15(8):749-57
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486 Chen L et al. Trim28 contributes to EMT via regulation of E-cadherin and N-cadherin in lung cancer cell lines. PLoS ONE 2014;9(7):e101040
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487 Jin G et al. Protein O-glucosyltransferase 1 overexpression downregulates p16 in BT474 human breast cancer cells. Oncol Lett 2014 Aug;8(2):594-600
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488 Chen MF et al. Transforming growth factor&#x2011;&#x3B2;1 induces epithelial&#x2011;mesenchymal transition and increased expression of matrix metalloproteinase&#x2011;16 via miR&#x2011;200b downregulation in bladder cancer cells. Mol Med Rep 2014 Sep;10(3
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489 Papadimitropoulos A et al. Expansion of human mesenchymal stromal cells from fresh bone marrow in a 3D scaffold-based system under direct perfusion. PLoS ONE 2014;9(7):e102359
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490 Mahoney JE et al. The hippo pathway effector Yap controls patterning and differentiation of airway epithelial progenitors. Dev. Cell 2014 Jul;30(2):137-50
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491 Mc Guire C et al. Pharmacological inhibition of MALT1 protease activity protects mice in a mouse model of multiple sclerosis. J Neuroinflammation 2014;11:124
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492 Okada Y et al. TRPA1 is required for TGF-&#x3B2; signaling and its loss blocks inflammatory fibrosis in mouse corneal stroma. Lab. Invest. 2014 Sep;94(9):1030-41
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493 Han L et al. The E3 deubiquitinase USP17 is a positive regulator of retinoic acid-related orphan nuclear receptor &#x3B3;t (ROR&#x3B3;t) in Th17 cells. J. Biol. Chem. 2014 Sep;289(37):25546-55
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494 Neumann C et al. Role of Blimp-1 in programing Th effector cells into IL-10 producers. J. Exp. Med. 2014 Aug;211(9):1807-19
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495 Iwaisako K et al. Origin of myofibroblasts in the fibrotic liver in mice. Proc. Natl. Acad. Sci. U.S.A. 2014 Aug;111(32):E3297-305
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496 Zhou Y et al. Secreted fibroblast-derived miR-34a induces tubular cell apoptosis in fibrotic kidney. J. Cell. Sci. 2014 Oct;127(Pt 20):4494-506
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497 Cheng T et al. Transforming growth factor-&#x3B2;-induced miR&#x2011;143 expression in regulation of non-small cell lung cancer cell viability and invasion capacity in vitro and in vivo. Int. J. Oncol. 2014 Nov;45(5):1977-88
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498 Tobar N et al. c-Jun N terminal kinase modulates NOX-4 derived ROS production and myofibroblasts differentiation in human breast stromal cells. BMC Cancer 2014;14:640
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499 Normanton M et al. Interleukin 7 plays a role in T lymphocyte apoptosis inhibition driven by mesenchymal stem cell without favoring proliferation and cytokines secretion. PLoS ONE 2014;9(9):e106673
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500 Xiao GY et al. Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy. PLoS ONE 2014;9(9):e106538
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501 Kuang DM et al. B7-H1-expressing antigen-presenting cells mediate polarization of protumorigenic Th22 subsets. J. Clin. Invest. 2014 Oct;124(10):4657-67
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502 Marfà S et al. Lack of a 5.9 kDa peptide C-terminal fragment of fibrinogen &#x3B1; chain precedes fibrosis progression in patients with liver disease. PLoS ONE 2014;9(10):e109254
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503 Stinson SE et al. D prostanoid receptor 2 (chemoattractant receptor-homologous molecule expressed on TH2 cells) protein expression in asthmatic patients and its effects on bronchial epithelial cells. J. Allergy Clin. Immunol. 2015 Feb;135(2):395-406
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504 Cao Y et al. Mechanisms of endothelial to mesenchymal transition in the retina in diabetes. Invest. Ophthalmol. Vis. Sci. 2014 Nov;55(11):7321-31
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505 Jolly L et al. Influenza promotes collagen deposition via &#x3B1;v&#x3B2;6 integrin-mediated transforming growth factor &#x3B2; activation. J. Biol. Chem. 2014 Dec;289(51):35246-63
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506 Bohnsack RN et al. Expression of insulin-like growth factor 2 receptor in corneal keratocytes during differentiation and in response to wound healing. Invest. Ophthalmol. Vis. Sci. 2014 Dec;55(12):7697-708
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507 Li J et al. The anti-proliferative function of the TGF-&#x3B2;1 signaling pathway involves the repression of the oncogenic TBX2 by its homologue TBX3. J. Biol. Chem. 2014 Dec;289(51):35633-43
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508 Eun SY et al. 4-1BB ligand signaling to T cells limits T cell activation. J. Immunol. 2015 Jan;194(1):134-41
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509 Presnell SR et al. Human natural killer cell microRNA: differential expression of MIR181A1B1 and MIR181A2B2 genes encoding identical mature microRNAs. Genes Immun. ;16(1):89-98
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510 Vijayakumar V et al. Tyrosine phosphorylation of WIP releases bound WASP and impairs podosome assembly in macrophages. J. Cell. Sci. 2015 Jan;128(2):251-65
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511 Chen M et al. Triptolide inhibits TGF-&#x3B2;1-induced cell proliferation in rat airway smooth muscle cells by suppressing Smad signaling. Exp. Cell Res. 2015 Feb;331(2):362-8
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512 Duan LJ et al. MiR-133 modulates TGF-&#x3B2;1-induced bladder smooth muscle cell hypertrophic and fibrotic response: implication for a role of microRNA in bladder wall remodeling caused by bladder outlet obstruction. Cell. Signal. 2015 Feb;27(2):215-27
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513 Rutz S et al. Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells. Nature 2015 Feb;518(7539):417-21
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514 Wang J et al. Novel mechanism of macrophage-mediated metastasis revealed in a zebrafish model of tumor development. Cancer Res. 2015 Jan;75(2):306-15
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515 Gordian E et al. Transforming growth factor &#x3B2; signaling overcomes dasatinib resistance in lung cancer. PLoS ONE 2014;9(12):e114131
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516 Galvagni F et al. Snai1 promotes ESC exit from the pluripotency by direct repression of self-renewal genes. Stem Cells 2015 Mar;33(3):742-50
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517 Nguyen LP et al. Role and species-specific expression of colon T cell homing receptor GPR15 in colitis. Nat. Immunol. 2015 Feb;16(2):207-13
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518 Woeller CF et al. Salinomycin and other polyether ionophores are a new class of antiscarring agent. J. Biol. Chem. 2015 Feb;290(6):3563-75
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519 Waight JD et al. Cutting edge: epigenetic regulation of Foxp3 defines a stable population of CD4+ regulatory T cells in tumors from mice and humans. J. Immunol. 2015 Feb;194(3):878-82
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520 Haffner-Luntzer M et al. Midkine-deficiency delays chondrogenesis during the early phase of fracture healing in mice. PLoS ONE 2014;9(12):e116282
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521 Sugita S et al. Inhibition of T-cell activation by retinal pigment epithelial cells derived from induced pluripotent stem cells. Invest. Ophthalmol. Vis. Sci. 2015 Feb;56(2):1051-62
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522 Ghiabi P et al. Breast cancer cells promote a notch-dependent mesenchymal phenotype in endothelial cells participating to a pro-tumoral niche. J Transl Med 2015 Jan;13(1):27
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523 Herov叩 M et al. ChemR23, the receptor for chemerin and resolvin E1, is expressed and functional on M1 but not on M2 macrophages. J. Immunol. 2015 Mar;194(5):2330-7
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524 Czysz K et al. DMSO efficiently down regulates pluripotency genes in human embryonic stem cells during definitive endoderm derivation and increases the proficiency of hepatic differentiation. PLoS ONE 2015;10(2):e0117689
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525 Narcisi R et al. Long-term expansion, enhanced chondrogenic potential, and suppression of endochondral ossification of adult human MSCs via WNT signaling modulation. Stem Cell Reports 2015 Mar;4(3):459-72
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526 Mu Y et al. TGF&#x3B2;-induced phosphorylation of Par6 promotes migration and invasion in prostate cancer cells. Br. J. Cancer 2015 Mar;112(7):1223-31
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527 W旦ltje K et al. Serum induces transcription of Hey1 and Hey2 genes by Alk1 but not Notch signaling in endothelial cells. PLoS ONE 2015;10(3):e0120547
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528 Schmitt-Ney M et al. The PAX3-FOXO1 fusion protein present in rhabdomyosarcoma interferes with normal FOXO activity and the TGF-&#x3B2; pathway. PLoS ONE 2015;10(3):e0121474
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529 Chan N et al. Attenuation of choroidal neovascularization by histone deacetylase inhibitor. PLoS ONE 2015;10(3):e0120587
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530 Jia D et al. Pyrroloquinoline-quinone suppresses liver fibrogenesis in mice. PLoS ONE 2015;10(3):e0121939
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532 Cruet-Hennequart S et al. Radiation-induced alterations of osteogenic and chondrogenic differentiation of human mesenchymal stem cells. PLoS ONE 2015;10(3):e0119334
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533 Klimatcheva E et al. CXCL13 antibody for the treatment of autoimmune disorders. BMC Immunol. 2015;16:6
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534 Young K et al. BMP9 Crosstalk with the Hippo Pathway Regulates Endothelial Cell Matricellular and Chemokine Responses. PLoS ONE 2015;10(4):e0122892
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535 Sun Y et al. Mesenchymal stem cells from patients with rheumatoid arthritis display impaired function in inhibiting Th17 cells. J Immunol Res 2015;2015:284215
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536 Rojas-Fernandez A et al. Rapid generation of endogenously driven transcriptional reporters in cells through CRISPR/Cas9. Sci Rep 2015;5:9811
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537 Truchetet ME et al. Interleukin-17A+ cell counts are increased in systemic sclerosis skin and their number is inversely correlated with the extent of skin involvement. Arthritis Rheum. 2013 May;65(5):1347-56
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538 Shinojima N et al. TGF-&#x3B2; mediates homing of bone marrow-derived human mesenchymal stem cells to glioma stem cells. Cancer Res. 2013 Apr;73(7):2333-44
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539 Tannetta DS et al. Characterisation of syncytiotrophoblast vesicles in normal pregnancy and pre-eclampsia: expression of Flt-1 and endoglin. PLoS ONE 2013;8(2):e56754
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540 Li R et al. Curcumin inhibits transforming growth factor-&#x3B2;1-induced EMT via PPAR&#x3B3; pathway, not Smad pathway in renal tubular epithelial cells. PLoS ONE 2013;8(3):e58848
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541 Ammann JU et al. Butyrophilin Btn2a2 inhibits TCR activation and phosphatidylinositol 3-kinase/Akt pathway signaling and induces Foxp3 expression in T lymphocytes. J. Immunol. 2013 May;190(10):5030-6
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542 Park JT et al. FOG2 protein down-regulation by transforming growth factor-&#x3B2;1-induced microRNA-200b/c leads to Akt kinase activation and glomerular mesangial hypertrophy related to diabetic nephropathy. J. Biol. Chem. 2013 Aug;288(31):22469-80
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543 Wang B et al. Transforming growth factor-&#x3B2;1-mediated renal fibrosis is dependent on the regulation of transforming growth factor receptor 1 expression by let-7b. Kidney Int. 2014 Feb;85(2):352-61
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544 Keune WJ et al. Low PIP4K2B expression in human breast tumors correlates with reduced patient survival: A role for PIP4K2B in the regulation of E-cadherin expression. Cancer Res. 2013 Dec;73(23):6913-25
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545 Schwartze JT et al. Glucocorticoids recruit Tgfbr3 and Smad1 to shift transforming growth factor-&#x3B2; signaling from the Tgfbr1/Smad2/3 axis to the Acvrl1/Smad1 axis in lung fibroblasts. J. Biol. Chem. 2014 Feb;289(6):3262-75
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546 Krimmer D et al. Exposure to biomass smoke extract enhances fibronectin release from fibroblasts. PLoS ONE 2013;8(12):e83938
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547 Hou S et al. Follicular dendritic cell secreted protein FDC-SP controls IgA production. Mucosal Immunol 2014 Jul;7(4):948-57
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548 Chen C et al. Telomerase governs immunomodulatory properties of mesenchymal stem cells by regulating FAS ligand expression. EMBO Mol Med 2014 Mar;6(3):322-34
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549 Rozycki M et al. The fate of the primary cilium during myofibroblast transition. Mol. Biol. Cell 2014 Mar;25(5):643-57
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550 Wang Y et al. Blocking Notch in endothelial cells prevents arteriovenous fistula failure despite CKD. J. Am. Soc. Nephrol. 2014 Apr;25(4):773-83
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551 Lee YC et al. Shorter daily dwelling time in peritoneal dialysis attenuates the epithelial-to-mesenchymal transition of mesothelial cells. BMC Nephrol 2014;15:35
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553 Olderøy MØ et al. Biochemical and structural characterization of neocartilage formed by mesenchymal stem cells in alginate hydrogels. PLoS ONE 2014;9(3):e91662
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554 Yu YL et al. Dual role of acetaminophen in promoting hepatoma cell apoptosis and kidney fibroblast proliferation. Mol Med Rep 2014 Jun;9(6):2077-84
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555 Penke LR et al. Prostaglandin E2 inhibits &#x3B1;-smooth muscle actin transcription during myofibroblast differentiation via distinct mechanisms of modulation of serum response factor and myocardin-related transcription factor-A. J. Biol. Chem. 2014 Jun;2
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556 G旦bel K et al. Phospholipase D1 mediates lymphocyte adhesion and migration in experimental autoimmune encephalomyelitis. Eur. J. Immunol. 2014 Aug;44(8):2295-305
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557 Zafar A et al. Chromatinized protein kinase C-&#x3B8; directly regulates inducible genes in epithelial to mesenchymal transition and breast cancer stem cells. Mol. Cell. Biol. 2014 Aug;34(16):2961-80
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558 Okabe H et al. Role of leukocyte cell-derived chemotaxin 2 as a biomarker in hepatocellular carcinoma. PLoS ONE 2014;9(6):e98817
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559 Pan CC et al. Src-mediated post-translational regulation of endoglin stability and function is critical for angiogenesis. J. Biol. Chem. 2014 Sep;289(37):25486-96
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560 Speck S et al. TGF-&#x3B2; signaling initiated in dendritic cells instructs suppressive effects on Th17 differentiation at the site of neuroinflammation. PLoS ONE 2014;9(7):e102390
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561 Chen KH et al. The AMPK agonist AICAR inhibits TGF-&#x3B2;1 induced activation of kidney myofibroblasts. PLoS ONE 2014;9(9):e106554
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562 Midgley AC et al. Hyaluronan regulates bone morphogenetic protein-7-dependent prevention and reversal of myofibroblast phenotype. J. Biol. Chem. 2015 May;290(18):11218-34
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563 Du J et al. Dynamic Sialylation in Transforming Growth Factor-&#x3B2; (TGF-&#x3B2;)-induced Epithelial to Mesenchymal Transition. J. Biol. Chem. 2015 May;290(19):12000-13
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564 Cho W et al. Suppressor of cytokine signaling 1 is a positive regulator of TGF-&#x3B2;-induced prostaglandin production in human follicular dendritic cell-like cells. J. Immunol. 2015 May;194(9):4287-97
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565 Giraldo CE et al. Effects of sodium citrate and acid citrate dextrose solutions on cell counts and growth factor release from equine pure-platelet rich plasma and pure-platelet rich gel. BMC Vet. Res. 2015;11:60
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566 Ilkow CS et al. Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity. Nat. Med. 2015 May;21(5):530-6
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567 Kuk H et al. 5Z-7-Oxozeanol Inhibits the Effects of TGF&#x3B2;1 on Human Gingival Fibroblasts. PLoS ONE 2015;10(4):e0123689
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568 Harris TL et al. Drak2 Does Not Regulate TGF-&#x3B2; Signaling in T Cells. PLoS ONE 2015;10(5):e0123650
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570 Pessina P et al. Novel and optimized strategies for inducing fibrosis in vivo: focus on Duchenne Muscular Dystrophy. Skelet Muscle 2014;4:7
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571 Kinugasa H et al. Mitochondrial SOD2 regulates epithelial-mesenchymal transition and cell populations defined by differential CD44 expression. Oncogene 2015 Oct;34(41):5229-39
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572 Kaushansky N et al. Role of a Novel Human Leukocyte Antigen-DQA1*01:02;DRB1*15:01 Mixed Isotype Heterodimer in the Pathogenesis of &quot;Humanized&quot; Multiple Sclerosis-like Disease. J. Biol. Chem. 2015 Jun;290(24):15260-78
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574 Watanabe-Takano H et al. DA-Raf-Mediated Suppression of the Ras--ERK Pathway Is Essential for TGF-&#x3B2;1-Induced Epithelial-Mesenchymal Transition in Alveolar Epithelial Type 2 Cells. PLoS ONE 2015;10(5):e0127888
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575 Singh I et al. High mobility group protein-mediated transcription requires DNA damage marker &#x3B3;-H2AX. Cell Res. 2015 Jul;25(7):837-50
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576 Fujita T et al. Identification and Characterization of CXCR4-Positive Gastric Cancer Stem Cells. PLoS ONE 2015;10(6):e0130808
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577 Lian M et al. Dietary n-3 PUFA Protects Mice from Con A Induced Liver Injury by Modulating Regulatory T Cells and PPAR-&#x3B3; Expression. PLoS ONE 2015;10(7):e0132741
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578 Pang MF et al. TGF-&#x3B2;1-induced EMT promotes targeted migration of breast cancer cells through the lymphatic system by the activation of CCR7/CCL21-mediated chemotaxis. Oncogene 2016 Feb;35(6):748-60
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579 Sahu SK et al. JNK-dependent gene regulatory circuitry governs mesenchymal fate. EMBO J. 2015 Aug;34(16):2162-81
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580 Roach KM et al. Lipoxin A4 Attenuates Constitutive and TGF-&#x3B2;1-Dependent Profibrotic Activity in Human Lung Myofibroblasts. J. Immunol. 2015 Sep;195(6):2852-60
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583 Sasaki CY et al. p(&#x2077;&#x2070;S&#x2076;K&#xB9;) in the TORC1 pathway is essential for the differentiation of Th17 Cells, but not Th1, Th2, or Treg cells in mice. Eur. J. Immunol. 2016 Jan;46(1):212-22
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584 Masani S et al. Redundant function of DNA ligase 1 and 3 in alternative end-joining during immunoglobulin class switch recombination. Proc. Natl. Acad. Sci. U.S.A. 2016 Feb;113(5):1261-6
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585 Lu G et al. Ligase I and ligase III mediate the DNA double-strand break ligation in alternative end-joining. Proc. Natl. Acad. Sci. U.S.A. 2016 Feb;113(5):1256-60
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586 Oliveira WN et al. The role of inflammatory and anti-inflammatory cytokines in the pathogenesis of human tegumentary leishmaniasis. Cytokine 2014 Apr;66(2):127-32
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587 Li H et al. Independent adipogenic and contractile properties of fibroblasts in Graves&#39; orbitopathy: an in vitro model for the evaluation of treatments. PLoS ONE 2014;9(4):e95586
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589 Fan MH et al. Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice. J. Biol. Chem. 2016 Apr;291(15):8070-89
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590 Schmidt A et al. Comparative Analysis of Protocols to Induce Human CD4+Foxp3+ Regulatory T Cells by Combinations of IL-2, TGF-beta, Retinoic Acid, Rapamycin and Butyrate. PLoS ONE 2016;11(2):e0148474
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596 Ohno S et al. Ablation of the N-type calcium channel ameliorates diabetic nephropathy with improved glycemic control and reduced blood pressure. Sci Rep 2016 Jun;6:27192
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598 Schr淡der M et al. CD1c-Expression by Monocytes - Implications for the Use of Commercial CD1c+ Dendritic Cell Isolation Kits. PLoS ONE 2016;11(6):e0157387
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600 Miller CL et al. Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci. Nat Commun 2016 Jul;7:12092
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601 Jiao J et al. Differentiation defect in neural crest-derived smooth muscle cells in patients with aortopathy associated with bicuspid aortic valves. EBioMedicine 2016 Aug;10:282-90
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602 Yu T et al. MicroRNA-491 regulates the proliferation and apoptosis of CD8(+) T cells. Sci Rep 2016 Aug;6:30923
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603 Liu Z et al. Fscn1 is required for the trafficking of TGF-&#x3B2; family type I receptors during endoderm formation. Nat Commun 2016 Aug;7:12603
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604 Josowitz R et al. Autonomous and Non-autonomous Defects Underlie Hypertrophic Cardiomyopathy in BRAF-Mutant hiPSC-Derived Cardiomyocytes. Stem Cell Reports 2016 Sep;7(3):355-69
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606 Boyan BD et al. 24R,25-Dihydroxyvitamin D3 Protects against Articular Cartilage Damage following Anterior Cruciate Ligament Transection in Male Rats. PLoS ONE 2016;11(8):e0161782
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610 Hu BL et al. Interleukin-22 ameliorates liver fibrosis through miR-200a/beta-catenin. Sci Rep 2016 Nov;6:36436
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611 Le MX et al. Kin17 facilitates multiple double-strand break repair pathways that govern B cell class switching. Sci Rep 2016 Nov;6:37215
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612 Chaudhury A et al. CELF1 is a central node in post-transcriptional regulatory programmes underlying EMT. Nat Commun 2016 Nov;7:13362
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613 Chanda D et al. Developmental Reprogramming in Mesenchymal Stromal Cells of Human Subjects with Idiopathic Pulmonary Fibrosis. Sci Rep 2016 Nov;6:37445
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614 Li YL et al. GDF15 contributes to radioresistance and cancer stemness of head and neck cancer by regulating cellular reactive oxygen species via a SMAD-associated signaling pathway. Oncotarget 2017 Jan;8(1):1508-1528
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615 Bayin NS et al. Patient-Specific Screening Using High-Grade Glioma Explants to Determine Potential Radiosensitization by a TGF-&#x3B2; Small Molecule Inhibitor. Neoplasia 2016 Dec;18(12):795-805
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616 Kusumoto H et al. Podocalyxin influences malignant potential by controlling epithelial-mesenchymal transition in lung adenocarcinoma. Cancer Sci. 2017 Mar;108(3):528-535
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617 Suzuki-Yamazaki N et al. IL-10 production in murine IgM(+) CD138(hi) cells is driven by Blimp-1 and downregulated in class-switched cells. Eur. J. Immunol. 2017 Mar;47(3):493-503
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618 Okada Y et al. Loss of TRPV4 Function Suppresses Inflammatory Fibrosis Induced by Alkali-Burning Mouse Corneas. PLoS ONE 2016;11(12):e0167200
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624 Pap D et al. Microarray Analysis Reveals Increased Expression of Matrix Metalloproteases and Cytokines of Interleukin-20 Subfamily in the Kidneys of Neonate Rats Underwent Unilateral Ureteral Obstruction: A Potential Role of IL-24 in the Regulation of Inf
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625 Hammers DW et al. Supraphysiological levels of GDF11 induce striated muscle atrophy. EMBO Mol Med 2017 Apr;9(4):531-544
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626 Ruiz-Carpio V et al. Genomic reprograming analysis of the Mesothelial to Mesenchymal Transition identifies biomarkers in peritoneal dialysis patients. Sci Rep 2017 Mar;7:44941
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627 McCauley KB et al. Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling. Cell Stem Cell 2017 Jun;20(6):844-857.e6
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628 Ghatak S et al. Transforming growth factor &#x3B2;1 (TGF&#x3B2;1)-induced CD44V6-NOX4 signaling in pathogenesis of idiopathic pulmonary fibrosis. J. Biol. Chem. 2017 Jun;292(25):10490-10519
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629 Zhou D et al. Cytidine monophosphate kinase is inhibited by the TGF-&#x3B2; signalling pathway through the upregulation of miR-130b-3p in human epithelial ovarian cancer. Cell. Signal. 2017 Jul;35:197-207
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630 Whelan KA et al. Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance. Oncogene 2017 Aug;36(34):4843-4858
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    Kakonen SM et al. Transforming growth factor-beta stimulates parathyroid hormone-related protein and osteolytic metastases via Smad and mitogen-activated protein kinase signaling pathways. J. Biol. Chem. 2002 Jul;277(27):24571-8
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    Cheon H et al. Increased expression of pro-inflammatory cytokines and metalloproteinase-1 by TGF-beta1 in synovial fibroblasts from rheumatoid arthritis and normal individuals. Clin. Exp. Immunol. 2002 Mar;127(3):547-52
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    Species: Human, Application: Bioassay, Sample type: Whole Cells
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    Banas B et al. Roles of SLC/CCL21 and CCR7 in human kidney for mesangial proliferation, migration, apoptosis, and tissue homeostasis. J. Immunol. 2002 May;168(9):4301-7
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    Sombroek CC et al. Prostanoids play a major role in the primary tumor-induced inhibition of dendritic cell differentiation. J. Immunol. 2002 May;168(9):4333-43
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    Liang CL et al. Epstein-Barr virus BZLF1 gene is activated by transforming growth factor-beta through cooperativity of Smads and c-Jun/c-Fos proteins. J. Biol. Chem. 2002 Jun;277(26):23345-57
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    Schmidt A et al. Induction of a hypertrophic growth status of coronary smooth muscle cells is associated with an overexpression of TGF-beta. Eur. J. Cell Biol. 2002 Mar;81(3):138-44
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    Species: Bovine, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Yan YT et al. Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway. Mol. Cell. Biol. 2002 Jul;22(13):4439-49
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    Hagimoto N et al. TGF-beta 1 as an enhancer of Fas-mediated apoptosis of lung epithelial cells. J. Immunol. 2002 Jun;168(12):6470-8
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    Ewan KB et al. Latent transforming growth factor-beta activation in mammary gland: regulation by ovarian hormones affects ductal and alveolar proliferation. Am. J. Pathol. 2002 Jun;160(6):2081-93
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    Rosado E et al. Transforming growth factor-beta1 regulation of growth zone chondrocytes is mediated by multiple interacting pathways. Biochim. Biophys. Acta 2002 Jun;1590(1-3):1-15
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    PubMed
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    Bauer BS et al. Latent and active transforming growth factor beta1 released from genetically modified keratinocytes modulates extracellular matrix expression by dermal fibroblasts in a coculture system. J. Invest. Dermatol. 2002 Aug;119(2):456-63
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    Zhao W et al. Suppression of in vivo tumorigenicity of rat hepatoma cell line KDH-8 cells by soluble TGF-beta receptor type II. Cancer Immunol. Immunother. 2002 Sep;51(7):381-8
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    Huaux F et al. A profibrotic function of IL-12p40 in experimental pulmonary fibrosis. J. Immunol. 2002 Sep;169(5):2653-61
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    Wadhwa M et al. Cytokine levels as performance indicators for white blood cell reduction of platelet concentrates. Vox Sang. 2002 Aug;83(2):125-36
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    Barton LF et al. Regulation of immunoproteasome subunit expression in vivo following pathogenic fungal infection. J. Immunol. 2002 Sep;169(6):3046-52
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    Rutella S et al. Role for granulocyte colony-stimulating factor in the generation of human T regulatory type 1 cells. Blood 2002 Oct;100(7):2562-71
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    Enzmann V et al. Influence of interleukin 10 and transforming growth factor-beta on T cell stimulation through allogeneic retinal pigment epithelium cells in vitro. Ophthalmic Res. ;34(4):232-40
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    Bendre MS et al. Expression of interleukin 8 and not parathyroid hormone-related protein by human breast cancer cells correlates with bone metastasis in vivo. Cancer Res. 2002 Oct;62(19):5571-9
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    Species: Human, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Tavassoli M et al. Tamoxifen inhibits the growth of head and neck cancer cells and sensitizes these cells to cisplatin induced-apoptosis: role of TGF-beta1. Carcinogenesis 2002 Oct;23(10):1569-75
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    Seoane J et al. Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage. Nature 2002 Oct;419(6908):729-34
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    Ishisaki A et al. Human umbilical vein endothelium-derived cells retain potential to differentiate into smooth muscle-like cells. J. Biol. Chem. 2003 Jan;278(2):1303-9
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    Scharstuhl A et al. Loss of transforming growth factor counteraction on interleukin 1 mediated effects in cartilage of old mice. Ann. Rheum. Dis. 2002 Dec;61(12):1095-8
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    Liu C et al. Smads 2 and 3 are differentially activated by transforming growth factor-beta (TGF-beta ) in quiescent and activated hepatic stellate cells. Constitutive nuclear localization of Smads in activated cells is TGF-beta-independent. J. Biol. Chem.
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    Huaux F et al. Dual roles of IL-4 in lung injury and fibrosis. J. Immunol. 2003 Feb;170(4):2083-92
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    Ashcroft GS et al. Estrogen modulates cutaneous wound healing by downregulating macrophage migration inhibitory factor. J. Clin. Invest. 2003 May;111(9):1309-18
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    Hanna J et al. CXCL12 expression by invasive trophoblasts induces the specific migration of CD16- human natural killer cells. Blood 2003 Sep;102(5):1569-77
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    Luckhart S et al. Mammalian transforming growth factor beta1 activated after ingestion by Anopheles stephensi modulates mosquito immunity. Infect. Immun. 2003 Jun;71(6):3000-9
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    Giusti C et al. Transforming growth factor beta-1 and amphiregulin act in synergy to increase the production of urokinase-type plasminogen activator in transformed breast epithelial cells. Int. J. Cancer 2003 Jul;105(6):769-78
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    PubMed
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    Levenberg S et al. Differentiation of human embryonic stem cells on three-dimensional polymer scaffolds. Proc. Natl. Acad. Sci. U.S.A. 2003 Oct;100(22):12741-6
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    Species: Human, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Matsuyama S et al. SB-431542 and Gleevec inhibit transforming growth factor-beta-induced proliferation of human osteosarcoma cells. Cancer Res. 2003 Nov;63(22):7791-8
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    PubMed
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    Sekiya T et al. Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells. J. Biol. Chem. 2004 Feb;279(8):6840-6
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    Species: Human, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Holland TA et al. Transforming growth factor-beta 1 release from oligo(poly(ethylene glycol) fumarate) hydrogels in conditions that model the cartilage wound healing environment. J Control Release 2004 Jan;94(1):101-14
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    Application: Microparticle Release, Sample Type: Gelatin Microparticles
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    PubMed
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    Calle Y et al. WASp deficiency in mice results in failure to form osteoclast sealing zones and defects in bone resorption. Blood 2004 May;103(9):3552-61
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    PubMed
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    Leach RE et al. Heparin-binding EGF-like growth factor regulates human extravillous cytotrophoblast development during conversion to the invasive phenotype. Dev. Biol. 2004 Feb;266(2):223-37
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    Application: Bioassay, Sample Type: Whole Cells
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    S叩nchez-Elsner T et al. A cross-talk between hypoxia and TGF-beta orchestrates erythropoietin gene regulation through SP1 and Smads. J. Mol. Biol. 2004 Feb;336(1):9-24
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    Application: Bioassay, Sample Type: Whole Cells
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    Robertson H et al. Chronic renal allograft dysfunction: the role of T cell-mediated tubular epithelial to mesenchymal cell transition. J. Am. Soc. Nephrol. 2004 Feb;15(2):390-7
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    Species: Human, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Nishishita T et al. Angiopoietin 1, PDGF-B, and TGF-beta gene regulation in endothelial cell and smooth muscle cell interaction. J. Cell. Biochem. 2004 Feb;91(3):584-93
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    Species: Human, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Takahashi M et al. Immature dendritic cells reduce proinflammatory cytokine production by a coculture of macrophages and apoptotic cells in a cell-to-cell contact-dependent manner. J. Leukoc. Biol. 2004 May;75(5):865-73
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    Bhowmick NA et al. TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia. Science 2004 Feb;303(5659):848-51
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    R鱈os R et al. Differential response to exogenous and endogenous myostatin in myoblasts suggests that myostatin acts as an autocrine factor in vivo. Endocrinology 2004 Jun;145(6):2795-803
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    Species: Human, Mouse, Rat, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Studer RK et al. Chondrocyte response to growth factors is modulated by p38 mitogen-activated protein kinase inhibition. Arthritis Res. Ther. 2004;6(1):R56-R64
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    Chen C et al. Two modes by which Lefty proteins inhibit nodal signaling. Curr. Biol. 2004 Apr;14(7):618-24
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    Conley BA et al. Endoglin controls cell migration and composition of focal adhesions: function of the cytosolic domain. J. Biol. Chem. 2004 Jun;279(26):27440-9
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    Zheng SG et al. Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10. J. Immunol. 2004 May;172(9):5213-21
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    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
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    Torrealba JR et al. Metastable tolerance to rhesus monkey renal transplants is correlated with allograft TGF-beta 1+CD4+ T regulatory cell infiltrates. J. Immunol. 2004 May;172(9):5753-64
    Torrealba JR et al
    2004/01/01
  • 備考:
    Application: Western Blot
  • 参照:
    PubMed
  • No.: 65
  • 文献情報:
    Bechara RI et al. Transforming growth factor beta1 expression and activation is increased in the alcoholic rat lung. Am. J. Respir. Crit. Care Med. 2004 Jul;170(2):188-94
    Bechara RI et al
    2004/01/01
  • 備考:
    Application: Bioassay, Sample Type: Cell Lysates
  • 参照:
    PubMed
  • No.: 66
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    Cosgrove GP et al. Pigment epithelium-derived factor in idiopathic pulmonary fibrosis: a role in aberrant angiogenesis. Am. J. Respir. Crit. Care Med. 2004 Aug;170(3):242-51
    Cosgrove GP et al
    2004/01/01
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    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 67
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    Barksdale AR et al. Regulation of arginase expression by T-helper II cytokines and isoproterenol. Surgery 2004 May;135(5):527-35
    Barksdale AR et al
    2004/01/01
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    Species: Mouse, Application: Bioassay, Sample type: Whole Cells
  • 参照:
    PubMed
  • No.: 68
  • 文献情報:
    Wildemann B et al. Local delivery of growth factors from coated titanium plates increases osteotomy healing in rats. Bone 2004 May;34(5):862-8
    Wildemann B et al
    2004/01/01
  • 備考:
    Application: In Vivo, Sample Type: Bone Implant
  • 参照:
    PubMed
  • No.: 69
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    Pociask DA et al. Asbestos-derived reactive oxygen species activate TGF-beta1. Lab. Invest. 2004 Aug;84(8):1013-23
    Pociask DA et al
    2004/01/01
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    Application: Bioassay
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    PubMed
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    Huang SS et al. Cellular growth inhibition by TGF-beta1 involves IRS proteins. FEBS Lett. 2004 May;565(1-3):117-21
    Huang SS et al
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    Species: Mink, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Karst M et al. Roles of stromal cell RANKL, OPG, and M-CSF expression in biphasic TGF-beta regulation of osteoclast differentiation. J. Cell. Physiol. 2004 Jul;200(1):99-106
    Karst M et al
    2004/01/01
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    Species: Mouse, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Bosnakovski D et al. Chondrogenic differentiation of bovine bone marrow mesenchymal stem cells in pellet cultural system. Exp. Hematol. 2004 May;32(5):502-9
    Bosnakovski D et al
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    Application: Bioassay
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    PubMed
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    Eriksson M et al. Unique phenotype of human uterine NK cells and their regulation by endogenous TGF-beta. J. Leukoc. Biol. 2004 Sep;76(3):667-75
    Eriksson M et al
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Zhu X et al. Myostatin signaling through Smad2, Smad3 and Smad4 is regulated by the inhibitory Smad7 by a negative feedback mechanism. Cytokine 2004 Jun;26(6):262-72
    Zhu X et al
    2004/01/01
  • 備考:
    Species: Human, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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  • 文献情報:
    Phillips TM. Rapid analysis of inflammatory cytokines in cerebrospinal fluid using chip-based immunoaffinity electrophoresis. Electrophoresis 2004 Jun;25(10-11):1652-9
    Phillips TM
    2004/01/01
  • 備考:
    Application: ChIP Standard
  • 参照:
    PubMed
  • No.: 76
  • 文献情報:
    Pratsinis H et al. Differential proliferative response of fetal and adult human skin fibroblasts to transforming growth factor-beta. Wound Repair Regen ;12(3):374-83
    Pratsinis H et al
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    Species: Human, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Kawai T et al. Efficient cardiomyogenic differentiation of embryonic stem cell by fibroblast growth factor 2 and bone morphogenetic protein 2. Circ. J. 2004 Jul;68(7):691-702
    Kawai T et al
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    Species: Mouse, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Wildemann B et al. Quantification, localization, and expression of IGF-I and TGF-beta1 during growth factor-stimulated fracture healing. Calcif. Tissue Int. 2004 Apr;74(4):388-97
    Wildemann B et al
    2004/01/01
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    Application: In Vivo
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    PubMed
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    Faucheux C et al. Recapitulation of the parathyroid hormone-related peptide-Indian hedgehog pathway in the regenerating deer antler. Dev. Dyn. 2004 Sep;231(1):88-97
    Faucheux C et al
    2004/01/01
  • 備考:
    Species: Deer - Cervus elaphus, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Wolk K et al. IL-22 increases the innate immunity of tissues. Immunity 2004 Aug;21(2):241-54
    Wolk K et al
    2004/01/01
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
  • No.: 81
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    Ogawa N et al. Expression of interferon-inducible T cell alpha chemoattractant (CXCL11) in the salivary glands of patients with Sjテθ津つカgren&#39;s syndrome. Clin. Immunol. 2004 Sep;112(3):235-8
    Ogawa N et al
    2004/01/01
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    Species: Human, Application: Bioassay, Whole Cells
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    PubMed
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    Tardif G et al. Differential gene expression and regulation of the bone morphogenetic protein antagonists follistatin and gremlin in normal and osteoarthritic human chondrocytes and synovial fibroblasts. Arthritis Rheum. 2004 Aug;50(8):2521-30
    Tardif G et al
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Fu S et al. TGF-beta induces Foxp3 + T-regulatory cells from CD4 + CD25 - precursors. Am. J. Transplant. 2004 Oct;4(10):1614-27
    Fu S et al
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Nagineni CN et al. Expression of PDGF and their receptors in human retinal pigment epithelial cells and fibroblasts: regulation by TGF-beta. J. Cell. Physiol. 2005 Apr;203(1):35-43
    Nagineni CN et al
    2005/01/01
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Allam JP et al. Transforming growth factor-beta1 regulates the expression of the high-affinity receptor for IgE on CD34 stem cell-derived CD1a dendritic cells in vitro. J. Invest. Dermatol. 2004 Oct;123(4):676-82
    Allam JP et al
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Maire M et al. Retention of transforming growth factor beta1 using functionalized dextran-based hydrogels. Biomaterials 2005 May;26(14):1771-80
    Maire M et al
    2005/01/01
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    Application: ELISA Standard,Loaded into hydrogels
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    PubMed
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    Kettunen P et al. Coordination of trigeminal axon navigation and patterning with tooth organ formation: epithelial-mesenchymal interactions, and epithelial Wnt4 and Tgfbeta1 regulate semaphorin 3a expression in the dental mesenchyme. Development 2005 Jan;
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    2005/01/01
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    Application: Bioassay, Sample Type: Whole Tissue
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    PubMed
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    Muraoka-Cook RS et al. Conditional overexpression of active transforming growth factor beta1 in vivo accelerates metastases of transgenic mammary tumors. Cancer Res. 2004 Dec;64(24):9002-11
    Muraoka-Cook RS et al
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Castigli E et al. TACI and BAFF-R mediate isotype switching in B cells. J. Exp. Med. 2005 Jan;201(1):35-9
    Castigli E et al
    2005/01/01
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Yuan J et al. Langerhans cells derived from genetically modified human CD34+ hemopoietic progenitors are more potent than peptide-pulsed Langerhans cells for inducing antigen-specific CD8+ cytolytic T lymphocyte responses. J. Immunol. 2005 Jan;174(2):758-
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Mespl竪s B et al. Neuronal TGF-beta1 mediates IL-9/mast cell interaction and exacerbates excitotoxicity in newborn mice. Neurobiol. Dis. 2005 Feb;18(1):193-205
    Mespl竪s B et al
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    Application: In Vivo
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    PubMed
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    Rao PE et al. Differentiation and expansion of T cells with regulatory function from human peripheral lymphocytes by stimulation in the presence of TGF-{beta}. J. Immunol. 2005 Feb;174(3):1446-55
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Karl C et al. Neuronal precursor-specific activity of a human doublecortin regulatory sequence. J. Neurochem. 2005 Jan;92(2):264-82
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Fujita H et al. Differential production of Th1- and Th2-type chemokines by mouse Langerhans cells and splenic dendritic cells. J. Invest. Dermatol. 2005 Feb;124(2):343-50
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    2005/01/01
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Kanematsu A et al. Induction of smooth muscle cell-like phenotype in marrow-derived cells among regenerating urinary bladder smooth muscle cells. Am. J. Pathol. 2005 Feb;166(2):565-73
    Kanematsu A et al
    2005/01/01
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    Application: Bioassay, Sample Type: Cell Supernates
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    PubMed
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    Lyakh LA et al. TGF-beta and vitamin D3 utilize distinct pathways to suppress IL-12 production and modulate rapid differentiation of human monocytes into CD83+ dendritic cells. J. Immunol. 2005 Feb;174(4):2061-70
    Lyakh LA et al
    2005/01/01
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    Species: Human, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Ogden CA et al. Enhanced apoptotic cell clearance capacity and B cell survival factor production by IL-10-activated macrophages: implications for Burkitt&#39;s lymphoma. J. Immunol. 2005 Mar;174(5):3015-23
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Dulos J et al. CYP7B expression and activity in fibroblast-like synoviocytes from patients with rheumatoid arthritis: regulation by proinflammatory cytokines. Arthritis Rheum. 2005 Mar;52(3):770-8
    Dulos J et al
    2005/01/01
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Distler JH et al. Expression of interleukin-21 receptor in epidermis from patients with systemic sclerosis. Arthritis Rheum. 2005 Mar;52(3):856-64
    Distler JH et al
    2005/01/01
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Shiraki N et al. TGF-beta signaling potentiates differentiation of embryonic stem cells to Pdx-1 expressing endodermal cells. Genes Cells 2005 Jun;10(6):503-16
    Shiraki N et al
    2005/01/01
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Wang L et al. Activation of transforming growth factor-beta1/p38/Smad3 signaling in stromal cells requires reactive oxygen species-mediated MMP-2 activity during bone marrow damage. Stem Cells 2005 Sep;23(8):1122-34
    Wang L et al
    2005/01/01
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    Species: Human, Mouse, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Jung Y et al. Regulation of SDF-1 (CXCL12) production by osteoblasts; a possible mechanism for stem cell homing. Bone 2006 Apr;38(4):497-508
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    2006/01/01
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Puxeddu I et al. The CC chemokine eotaxin/CCL11 has a selective profibrogenic effect on human lung fibroblasts. J. Allergy Clin. Immunol. 2006 Jan;117(1):103-10
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Jerkic M et al. Reduced angiogenic responses in adult Endoglin heterozygous mice. Cardiovasc. Res. 2006 Mar;69(4):845-54
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    2006/01/01
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Yue Z et al. Wnt3a gradient converts radial to bilateral feather symmetry via topological arrangement of epithelia. Proc. Natl. Acad. Sci. U.S.A. 2006 Jan;103(4):951-5
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    2006/01/01
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    Application: In Vivo
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    PubMed
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    Gautier G et al. The class 6 semaphorin SEMA6A is induced by interferon-gamma and defines an activation status of langerhans cells observed in pathological situations. Am. J. Pathol. 2006 Feb;168(2):453-65
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    2006/01/01
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Esposito I et al. Tenascin C and annexin II expression in the process of pancreatic carcinogenesis. J. Pathol. 2006 Apr;208(5):673-85
    Esposito I et al
    2006/01/01
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Yuan J et al. Langerhans-type dendritic cells genetically modified to express full-length antigen optimally stimulate CTLs in a CD4-dependent manner. J. Immunol. 2006 Feb;176(4):2357-65
    Yuan J et al
    2006/01/01
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    L辿tuv辿 S et al. IL-17E upregulates the expression of proinflammatory cytokines in lung fibroblasts. J. Allergy Clin. Immunol. 2006 Mar;117(3):590-6
    L辿tuv辿 S et al
    2006/01/01
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Valencia X et al. TNF downmodulates the function of human CD4+CD25hi T-regulatory cells. Blood 2006 Jul;108(1):253-61
    Valencia X et al
    2006/01/01
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Ostroukhova M et al. Treg-mediated immunosuppression involves activation of the Notch-HES1 axis by membrane-bound TGF-beta. J. Clin. Invest. 2006 Apr;116(4):996-1004
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    2006/01/01
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Neurohr C et al. Activation of transforming growth factor-beta by the integrin alphavbeta8 delays epithelial wound closure. Am. J. Respir. Cell Mol. Biol. 2006 Aug;35(2):252-9
    Neurohr C et al
    2006/01/01
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    Species: Human, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Nguyen AN et al. Normalizing the bone marrow microenvironment with p38 inhibitor reduces multiple myeloma cell proliferation and adhesion and suppresses osteoclast formation. Exp. Cell Res. 2006 Jun;312(10):1909-23
    Nguyen AN et al
    2006/01/01
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    Species: Human, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Wolk K et al. IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis. Eur. J. Immunol. 2006 May;36(5):1309-23
    Wolk K et al
    2006/01/01
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    Species: Human, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Rhodes KE et al. The injury response of oligodendrocyte precursor cells is induced by platelets, macrophages and inflammation-associated cytokines. Neuroscience 2006 Jun;140(1):87-100
    Rhodes KE et al
    2006/01/01
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    Species: Rat, Application: In Vivo
  • 参照:
    PubMed
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    Hollborn M et al. Signaling pathways involved in PDGF-evoked cellular responses in human RPE cells. Biochem. Biophys. Res. Commun. 2006 Jun;344(3):912-9
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Maeshima A et al. Activin A is an endogenous inhibitor of ureteric bud outgrowth from the Wolffian duct. Dev. Biol. 2006 Jul;295(2):473-85
    Maeshima A et al
    2006/01/01
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    Species: Rat, Application: Bioassay, Sample type: Whole Tissue
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    PubMed
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    Bettelli E et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006 May;441(7090):235-8
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Li Y et al. Transforming growth factor-alpha: a major human serum factor that promotes human keratinocyte migration. J. Invest. Dermatol. 2006 Sep;126(9):2096-105
    Li Y et al
    2006/01/01
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    Species: Human, Application: Bioassay, Whole Cells
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    PubMed
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  • 文献情報:
    Saika S et al. Loss of tumor necrosis factor alpha potentiates transforming growth factor beta-mediated pathogenic tissue response during wound healing. Am. J. Pathol. 2006 Jun;168(6):1848-60
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Yu H et al. Isolation of a novel population of multipotent adult stem cells from human hair follicles. Am. J. Pathol. 2006 Jun;168(6):1879-88
    Yu H et al
    2006/01/01
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Liu Y et al. A novel chemical-defined medium with bFGF and N2B27 supplements supports undifferentiated growth in human embryonic stem cells. Biochem. Biophys. Res. Commun. 2006 Jul;346(1):131-9
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Nam JS et al. Bone sialoprotein mediates the tumor cell-targeted prometastatic activity of transforming growth factor beta in a mouse model of breast cancer. Cancer Res. 2006 Jun;66(12):6327-35
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    Hayashida K et al. Syndecan-1 expression in epithelial cells is induced by transforming growth factor beta through a PKA-dependent pathway. J. Biol. Chem. 2006 Aug;281(34):24365-74
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    Species: Mouse, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Tong M et al. Histone deacetylase inhibitors and transforming growth factor-beta induce 15-hydroxyprostaglandin dehydrogenase expression in human lung adenocarcinoma cells. Biochem. Pharmacol. 2006 Sep;72(6):701-9
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    Species: Human, Application: Bioassay, Whole Cells
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    PubMed
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    Kollias HD et al. Smad7 promotes and enhances skeletal muscle differentiation. Mol. Cell. Biol. 2006 Aug;26(16):6248-60
    Kollias HD et al
    2006/01/01
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    Species: Mouse, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Wang S et al. Optimizing immunotherapy in multiple myeloma: Restoring the function of patients&#39; monocyte-derived dendritic cells by inhibiting p38 or activating MEK/ERK MAPK and neutralizing interleukin-6 in progenitor cells. Blood 2006 Dec;108(13):4071-7
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    Species: Human, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Hasegawa K et al. A method for the selection of human embryonic stem cell sublines with high replating efficiency after single-cell dissociation. Stem Cells 2006 Dec;24(12):2649-60
    Hasegawa K et al
    2006/01/01
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    Species: Human, Application: Bioassay, Sample type: Whole Cells
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    PubMed
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    Zeng L et al. Multipotent adult progenitor cells from swine bone marrow. Stem Cells 2006 Nov;24(11):2355-66
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
  • No.: 130
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    Letterio J et al. Transforming growth factor-beta1 sensitivity is altered in Abl-Myc- and Raf-Myc-induced mouse pre-B-cell tumors. Stem Cells 2006 Dec;24(12):2611-7
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    Ratnayake M et al. Human chondrocytes respond discordantly to the protein encoded by the osteoarthritis susceptibility gene GDF5. PLoS ONE 2014;9(1):e86590
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    Mirkina I et al. Phenotyping of human melanoma cells reveals a unique composition of receptor targets and a subpopulation co-expressing ErbB4, EPO-R and NGF-R. PLoS ONE 2014;9(1):e84417
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    Application: Bioassay, Sample Type: Whole Cells
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    Application: Bioassay, Sample Type: Whole Cells
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    Application: Bioassay, Sample Type: Whole Cells
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    Application: Bioassay, Sample Type: Whole Cells
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    Application: Bioassay, Sample Type: Whole Cell
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    Application: Bioassay, Sample Type: Whole Cells
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    Application: Bioassay, Sample Type: Whole Cells
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    Application: Bioassay, Sample Type: Whole Cells
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    Application: Bioassay, Sample Type: Cell culture
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    Application: Bioassay, Sample Type: Whole Cells
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed
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    PubMed
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    Bourcy M et al. Tissue Factor Induced by Epithelial-Mesenchymal Transition Triggers a Procoagulant State That Drives Metastasis of Circulating Tumor Cells. Cancer Res. 2016 Jul;76(14):4270-82
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    Ohno S et al. Ablation of the N-type calcium channel ameliorates diabetic nephropathy with improved glycemic control and reduced blood pressure. Sci Rep 2016 Jun;6:27192
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    PubMed
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    Li Q et al. Hepatitis C virus depends on E-cadherin as an entry factor and regulates its expression in epithelial-to-mesenchymal transition. Proc. Natl. Acad. Sci. U.S.A. 2016 07;113(27):7620-5
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    PubMed
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    PubMed
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    Mehrabian M et al. Prion Protein Deficiency Causes Diverse Proteome Shifts in Cell Models That Escape Detection in Brain Tissue. PLoS ONE 2016;11(6):e0156779
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    Miller CL et al. Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci. Nat Commun 2016 Jul;7:12092
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    Xiao X et al. EZH2 enhances the differentiation of fibroblasts into myofibroblasts in idiopathic pulmonary fibrosis. Physiol Rep 2016 Sep;4(17)
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    Hu BL et al. Interleukin-22 ameliorates liver fibrosis through miR-200a/beta-catenin. Sci Rep 2016 Nov;6:36436
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    Le MX et al. Kin17 facilitates multiple double-strand break repair pathways that govern B cell class switching. Sci Rep 2016 Nov;6:37215
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    Chaudhury A et al. CELF1 is a central node in post-transcriptional regulatory programmes underlying EMT. Nat Commun 2016 Nov;7:13362
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    Okada Y et al. Loss of TRPV4 Function Suppresses Inflammatory Fibrosis Induced by Alkali-Burning Mouse Corneas. PLoS ONE 2016;11(12):e0167200
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    Application: Bioassay, Sample Type: Whole Cells
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    Application: Bioassay, Sample Type: Whole Cells
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    PubMed