Anti-MLDP, Guinea Pig-Poly <Anti-OXPAT> <Anti-PAT-1>

データシート

• 商品コード：GP31
• メーカー：POG
• 包装：100μl
• 価格： ¥85,000
• 在庫：無(未発注)

マイリストに追加 マイリストに追加済

• No.： 1
• 文献情報：
  Pourteymour S et al. Perilipin 4 in human skeletal muscle: localization and effect of physical activity. Physiol Rep 2015 Aug;3(8)
  Pourteymour S et al
  2015/01/01
  
• 備考：
  Application: IHC
• 参照：
  

• No.： 2
• 文献情報：
  Ramos SV et al. Higher PLIN5 but not PLIN3 content in isolated skeletal muscle mitochondria following acute in vivo contraction in rat hindlimb. Physiol Rep 2014 Oct;2(10)
  Ramos SV et al
  2014/01/01
  
• 備考：
  Application: WB
• 参照：
  

• No.： 3
• 文献情報：
  Mason RR et al. PLIN5 deletion remodels intracellular lipid composition and causes insulin resistance in muscle. Mol Metab 2014 Sep;3(6):652-63
  Mason RR et al
  2014/01/01
  
• 備考：
  
• 参照：
  

• No.： 4
• 文献情報：
  Mason RR et al. Cellular localization and associations of the major lipolytic proteins in human skeletal muscle at rest and during exercise. PLoS ONE 2014;9(7):e103062
  Mason RR et al
  2014/01/01
  
• 備考：
  Application: IHC
• 参照：
  

• No.： 5
• 文献情報：
  Kuramoto K et al. Deficiency of a lipid droplet protein, perilipin 5, suppresses myocardial lipid accumulation, thereby preventing type 1 diabetes-induced heart malfunction. Mol. Cell. Biol. 2014 Jul;34(14):2721-31
  Kuramoto K et al
  2014/01/01
  
• 備考：
  
• 参照：
  

• No.： 6
• 文献情報：
  Macpherson RE et al. Skeletal muscle PLIN proteins, ATGL and CGI-58, interactions at rest and following stimulated contraction. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2013 Apr;304(8):R644-50
  Macpherson RE et al
  2013/01/01
  
• 備考：
  
• 参照：
  

• No.： 7
• 文献情報：
  Timmers S et al. Augmenting muscle diacylglycerol and triacylglycerol content by blocking fatty acid oxidation does not impede insulin sensitivity. Proc. Natl. Acad. Sci. U.S.A. 2012 Jul;109(29):11711-6
  Timmers S et al
  2012/01/01
  
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• 参照：
  

• No.： 8
• 文献情報：
  Bosma M et al. The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria. Histochem. Cell Biol. 2012 Feb;137(2):205-16
  Bosma M et al
  2012/01/01
  
• 備考：
  Application: WB, IF
• 参照：
  

• No.： 9
• 文献情報：
  MacPherson RE et al. Subcellular localization of skeletal muscle lipid droplets and PLIN family proteins OXPAT and ADRP at rest and following contraction in rat soleus muscle. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2012 Jan;302(1):R29-36
  MacPherson RE et al
  2012/01/01
  
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• 参照：
  

• No.： 10
• 文献情報：
  Timmers S et al. Paradoxical increase in TAG and DAG content parallel the insulin sensitizing effect of unilateral DGAT1 overexpression in rat skeletal muscle. PLoS ONE 2011;6(1):e14503
  Timmers S et al
  2011/01/01
  
• 備考：
  Application: WB
• 参照：
  

• No.： 11
• 文献情報：
  Gallardo-Montejano VI et al. Nuclear Perilipin 5 integrates lipid droplet lipolysis with PGC-1&#x3B1;/SIRT1-dependent transcriptional regulation of mitochondrial function. Nat Commun 2016 Aug;7:12723
  Gallardo-Montejano VI et al
  2016/01/01
  
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• 参照：
  

• No.： 12
• 文献情報：
  Dahlhoff M et al. PLIN2, the major perilipin regulated during sebocyte differentiation, controls sebaceous lipid accumulation in vitro and sebaceous gland size in vivo. Biochim. Biophys. Acta 2013 Oct;1830(10):4642-9
  Dahlhoff M et al
  2013/01/01
  
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• 参照：
  

• No.： 13
• 文献情報：
  Heid H et al. Lipid droplets, perilipins and cytokeratins--unravelled liaisons in epithelium-derived cells. PLoS ONE 2013;8(5):e63061
  Heid H et al
  2013/01/01
  
• 備考：
  
• 参照：
  

• No.： 14
• 文献情報：
  Barquissau V et al. White-to-brite conversion in human adipocytes promotes metabolic reprogramming towards fatty acid anabolic and catabolic pathways. Mol Metab 2016 May;5(5):352-65
  Barquissau V et al
  2016/01/01
  
• 備考：
  
• 参照：
  

• No.： 15
• 文献情報：
  Gemmink A et al. Decoration of intramyocellular lipid droplets with PLIN5 modulates fasting-induced insulin resistance and lipotoxicity in humans. Diabetologia 2016 May;59(5):1040-8
  Gemmink A et al
  2016/01/01
  
• 備考：
  
• 参照：
  

• No.： 16
• 文献情報：
  Billecke N et al. Perilipin 5 mediated lipid droplet remodelling revealed by coherent Raman imaging. Integr Biol (Camb) 2015 Apr;7(4):467-76
  Billecke N et al
  2015/01/01
  
• 備考：
  
• 参照：
  

• No.： 17
• 文献情報：
  Macpherson RE et al. Skeletal muscle PLIN3 and PLIN5 are serine phosphorylated at rest and following lipolysis during adrenergic or contractile stimulation. Physiol Rep 2013 Sep;1(4):e00084
  Macpherson RE et al
  2013/01/01
  
• 備考：
  
• 参照：
  

• No.： 18
• 文献情報：
  Yamaguchi T et al. MLDP, a novel PAT family protein localized to lipid droplets and enriched in the heart, is regulated by peroxisome proliferator-activated receptor alpha. J. Biol. Chem. 2006 May;281(20):14232-40
  Yamaguchi T et al
  2006/01/01
  
• 備考：
  
• 参照：
  

• No.： 19
• 文献情報：
  Trevino MB et al. Perilipin 5 regulates islet lipid metabolism and insulin secretion in a cAMP-dependent manner: implication of its role in the postprandial insulin secretion. Diabetes 2015 Apr;64(4):1299-310
  Trevino MB et al
  2015/01/01
  
• 備考：
  
• 参照：
  

• No.： 20
• 文献情報：
  Wang H et al. Unique regulation of adipose triglyceride lipase (ATGL) by perilipin 5, a lipid droplet-associated protein. J. Biol. Chem. 2011 May;286(18):15707-15
  Wang H et al
  2011/01/01
  
• 備考：
  
• 参照：
  

• No.： 21
• 文献情報：
  Gemmink A et al. Dissociation of intramyocellular lipid storage and insulin resistance in trained athletes and type 2 diabetes patients; involvement of perilipin 5? J. Physiol. (Lond.) 2017 Nov;
  Gemmink A et al
  2017/01/01
  
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• 参照：
  

• No.： 22
• 文献情報：
  Talbott, H. et al. Formation and characterization of lipid droplets of the bovine corpus luteum. Sci.Rep. 10, 11287 (2020)
  
  
• 備考：
  
• 参照：
  

• No.： 23
• 文献情報：
  Laurens, C. et al. Perilipin 5 fine-tunes lipid oxidation to metabolic demand and protects against lipotoxicity in skeletal muscle. Sci. Rep. 6, 1–12 (2016).
  
  
• 備考：
  
• 参照：
  

• No.： 24
• 文献情報：
  Daemen, S. et al. Distinct lipid droplet characteristics and distribution unmask the apparent contradiction of the athlete&#39;s paradox. Mol.Metab. 17, 71-81 (2018).
  
  
• 備考：
  
• 参照：
  

• No.： 25
• 文献情報：
  Pourteymour, S. et al. Perilipin 4 in human skeletal muscle: localization and effect of physical activity. Physiol. Rep. 3, (2015).
  
  
• 備考：
  
• 参照：
  

• No.： 26
• 文献情報：
  Macpherson, R. E. K. et al. Subcellular localization of skeletal muscle lipid droplets and PLIN family proteins OXPAT and ADRP at rest and following contraction in rat soleus muscle. Am. J. Physiol. - Regul. Integr. Comp. Physiol. -(2011).
  
  
• 備考：
  
• 参照：
  

• No.： 27
• 文献情報：
  Irungbam, K. et al. Cannabinoid receptor 1 knockout alleviates hepatic steatosis by downregulating perilipin 2. Lab.Invest. 100, 454-465 (2020)
  
  
• 備考：
  
• 参照：
  

• No.： 28
• 文献情報：
  Timmers, S. et al. Paradoxical Increase in TAG and DAG Content Parallel the Insulin Sensitizing Effect of Unilateral DGAT1 Overexpression in Rat Skeletal Muscle. PLoS One 6, (2011).
  
  
• 備考：
  
• 参照：
  

• No.： 29
• 文献情報：
  Barquissau, V. et al. White-to-brite conversion in human adipocytes promotes metabolic reprogramming towards fatty acid anabolic and catabolic pathways. Mol. Metab. 5, 352-365 (2016).
  
  
• 備考：
  
• 参照：
  

• No.： 30
• 文献情報：
  MacPherson, R. E. K., Ramos, S. V, Vandenboom, R., Roy, B. D. & Peters, S. J. Skeletal muscle PLIN proteins, ATGL and CGI-58, interactions at rest and following stimulated contraction. Am. J. Physiol. Regul. Integr. Comp. Physiol. 304, R644-50 (2013).
  
  
• 備考：
  
• 参照：
  

• No.： 31
• 文献情報：
  Gemmink, A. et al. Decoration of intramyocellular lipid droplets with PLIN5 modulates fasting-induced insulin resistance and lipotoxicity in humans. Diabetologia 59, 1040-8 (2016).
  
  
• 備考：
  
• 参照：
  

• No.： 32
• 文献情報：
  Zhu, Y. et al. Perilipin5 protects against lipotoxicity and alleviates endoplasmic reticulum stress in pancreatic 硫-cells. Nutr.Metab.(Lond). 16, 50 (2019)
  
  
• 備考：
  
• 参照：
  

• No.： 33
• 文献情報：
  Lee, M. et al. Rosiglitazone remodels the lipid droplet and britens human visceral and subcutaneous adipocytes ex vivo. J.Lipid.Res. 60, 856-868 (2019)
  
  
• 備考：
  
• 参照：
  

• No.： 34
• 文献情報：
  Timmers, S. et al. Augmenting muscle diacylglycerol and triacylglycerol content by blocking fatty acid oxidation does not impede insulin sensitivity. Proc. Natl. Acad. Sci. USA 109, 11711-11716 (2012).
  
  
• 備考：
  
• 参照：
  

• No.： 35
• 文献情報：
  Yamaguchi, T., Matsushita, S., Motojima, K., Hirose, F. & Osumi, T. MLDP, a novel PAT family protein localized to lipid droplets and enriched in the heart, is regulated by peroxisome proliferator-activated receptor alpha. J. Biol. Chem. 281, 14232-40 (20
  
  
• 備考：
  
• 参照：
  

• No.： 36
• 文献情報：
  Kuramoto, K. et al. Deficiency of a Lipid Droplet Protein, Perilipin 5, Suppresses Myocardial Lipid Accumulation, Thereby Preventing Type 1 Diabetes- Induced Heart Malfunction. Mol. Cell. Biol. -34, 2721-2731 (2014).
  
  
• 備考：
  
• 参照：
  

• No.： 37
• 文献情報：
  Gallardo-Montejano, V. I. et al. Nuclear Perilipin 5 integrates lipid droplet lipolysis with PGC-1a/SIRT1-dependent transcriptional regulation of mitochondrial function. Nat. Commun. 7, (2016).
  
  
• 備考：
  
• 参照：
  

• No.： 38
• 文献情報：
  Mason, R. R., Meex, R. C. R., Russell, A. P., Canny, B. J. & Watt, M. J. Cellular Localization and Associations of the Major Lipolytic Proteins in Human Skeletal Muscle at Rest and during Exercise. PLoS One 9, (2014).
  
  
• 備考：
  
• 参照：
  

• No.： 39
• 文献情報：
  Mardani, I. et al. Plin2-deficiency reduces lipophagy and results in increased lipid accumulation in the heart. Sci.Rep. 9, 6909 (2019)
  
  
• 備考：
  
• 参照：
  

• No.： 40
• 文献情報：
  Mason, R. R. et al. PLIN5 deletion remodels intracellular lipid composition and causes insulin resistance in muscle. Mol. Metab. 3, 652-663 (2014).
  
  
• 備考：
  
• 参照：
  

• No.： 41
• 文献情報：
  Trevino, M. B. et al. Perilipin 5 regulates islet lipid metabolism and insulin secretion in a cAMP-dependent manner: Implication of its role in the postprandial insulin secretion. Diabetes 64, 1299-1310 (2015).
  
  
• 備考：
  
• 参照：
  

• No.： 42
• 文献情報：
  Gemmink, A. et al. Lipid droplet dynamics and insulin sensitivity upon a 5-day high-fat diet in Caucasians and South Asians. Sci. Rep. 7, 1–9 (2017).
  
  
• 備考：
  
• 参照：
  

• No.： 43
• 文献情報：
  Ramos, S. V et al. Higher PLIN5 but not PLIN3 content in isolated skeletal muscle mitochondria following acute in vivo contraction in rat hindlimb. Physiol. Reports 2, (2014).
  
  
• 備考：
  
• 参照：
  

• No.： 44
• 文献情報：
  Billecke, N. et al. Perilipin 5 mediated lipid droplet remodelling revealed by coherent Raman imaging. Integr. Biol. (Camb). 7, 467-76 (2015).
  
  
• 備考：
  
• 参照：
  

• No.： 45
• 文献情報：
  Wang, H. et al. Unique regulation of adipose triglyceride lipase (ATGL) by perilipin 5, a lipid droplet-associated protein. J. Biol. Chem. 286, 15707-15715 (2011).
  
  
• 備考：
  
• 参照：
  

• No.： 46
• 文献情報：
  Macpherson, R. E. K., Vandenboom, R., Roy, B. D. & Peters, S. J. Skeletal muscle PLIN3 and PLIN5 are serine phosphorylated at rest and following lipolysis during adrenergic or contractile stimulation. Physioligal Reports 1, (2013).
  
  
• 備考：
  
• 参照：
  

• No.： 47
• 文献情報：
  Lian, J. et al. Ces1d deficiency protects against high-sucrose diet-induced hepatic triacylglycerol accumulation. J.Lipid.Res. 60, 880-891 (2019)
  
  
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• 参照：
  

• No.： 48
• 文献情報：
  Whytock, K. et al. Hormone-sensitive lipase preferentially redistributes to lipid droplets associated with perilipin-5 in human skeletal muscle during moderate-intensity exercise. J.Physiol. 596, 2077-2090 (2018)
  
  
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