価格表

在庫・価格 : 2024年05月18日 02時47分 現在

商品名 商品コード メーカー 包装 価格 在庫 リスト
Anti-p62, C-terminal, Guinea Pig-Poly <Anti-SQSTM1> <Anti-Sequestosome>
データシート
GP62-C POGプロジェン バイオテクニック
PROGEN Biotechnik GmbH
100 μl ¥89,000
(未発注)
追加

在庫・価格 : 2024年05月18日 02時47分 現在

Anti-p62, C-terminal, Guinea Pig-Poly <Anti-SQSTM1> <Anti-Sequestosome>

  • 商品コード:GP62-C
  • メーカー:POG
  • 包装:100μl
  • 価格: ¥89,000
  • 在庫:無(未発注)
使用文献
No. 文献情報 備考 参照
1 Puvirajesinghe TM et al. Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer. Nat Commun 2016;7:10318
Puvirajesinghe TM et al
2016/01/01
PubMed
2 Shi J et al. NBR1 is dispensable for PARK2-mediated mitophagy regardless of the presence or absence of SQSTM1. Cell Death Dis 2015;6:e1943
Shi J et al
2015/01/01
Application: WB PubMed
3 Agarwal S et al. Autophagy and endosomal trafficking inhibition by Vibrio cholerae MARTX toxin phosphatidylinositol-3-phosphate-specific phospholipase A1 activity. Nat Commun 2015;6:8745
Agarwal S et al
2015/01/01
Application: WB PubMed
4 Eino A et al. Sqstm1-GFP knock-in mice reveal dynamic actions of Sqstm1 during autophagy and under stress conditions in living cells. J. Cell. Sci. 2015 Dec;128(23):4453-61
Eino A et al
2015/01/01
PubMed
5 Pellegrini C et al. All-trans retinoic acid and rapamycin normalize Hutchinson Gilford progeria fibroblast phenotype. Oncotarget 2015 Oct;6(30):29914-28
Pellegrini C et al
2015/01/01
PubMed
6 Clayton EL et al. Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology. Acta Neuropathol. 2015 Oct;130(4):511-23
Clayton EL et al
2015/01/01
Application: IF PubMed
7 Newton PT et al. Pharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner. Autophagy 2015;11(9):1594-607
Newton PT et al
2015/01/01
PubMed
8 Felzen V et al. Estrogen receptor &#x3B1; regulates non-canonical autophagy that provides stress resistance to neuroblastoma and breast cancer cells and involves BAG3 function. Cell Death Dis 2015;6:e1812
Felzen V et al
2015/01/01
PubMed
9 Ruozi G et al. AAV-mediated in vivo functional selection of tissue-protective factors against ischaemia. Nat Commun 2015;6:7388
Ruozi G et al
2015/01/01
Application: WB PubMed
10 Milan E et al. A plastic SQSTM1/p62-dependent autophagic reserve maintains proteostasis and determines proteasome inhibitor susceptibility in multiple myeloma cells. Autophagy 2015;11(7):1161-78
Milan E et al
2015/01/01
Application: WB, IF PubMed
11 Echeverry N et al. Inhibition of autophagy sensitizes malignant pleural mesothelioma cells to dual PI3K/mTOR inhibitors. Cell Death Dis 2015;6:e1757
Echeverry N et al
2015/01/01
Application: WB PubMed
12 Akizu N et al. Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction. Nat. Genet. 2015 May;47(5):528-34
Akizu N et al
2015/01/01
PubMed
13 McMillan EM et al. Autophagic signaling and proteolytic enzyme activity in cardiac and skeletal muscle of spontaneously hypertensive rats following chronic aerobic exercise. PLoS ONE 2015;10(3):e0119382
McMillan EM et al
2015/01/01
Application: WB PubMed
14 Murrow L et al. ATG12-ATG3 interacts with Alix to promote basal autophagic flux and late endosome function. Nat. Cell Biol. 2015 Mar;17(3):300-10
Murrow L et al
2015/01/01
PubMed
15 Lim J et al. Proteotoxic stress induces phosphorylation of p62/SQSTM1 by ULK1 to regulate selective autophagic clearance of protein aggregates. PLoS Genet. 2015;11(2):e1004987
Lim J et al
2015/01/01
PubMed
16 Morimoto D et al. The unexpected role of polyubiquitin chains in the formation of fibrillar aggregates. Nat Commun 2015;6:6116
Morimoto D et al
2015/01/01
Application: WB, ICC PubMed
17 Arel-Dubeau AM et al. Cucurbitacin E has neuroprotective properties and autophagic modulating activities on dopaminergic neurons. Oxid Med Cell Longev 2014;2014:425496
Arel-Dubeau AM et al
2014/01/01
PubMed
18 Liu S et al. Disrupted autophagy after spinal cord injury is associated with ER stress and neuronal cell death. Cell Death Dis 2015;6:e1582
Liu S et al
2015/01/01
Application: WB, IHC PubMed
19 Sarkar C et al. Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury. Autophagy 2014;10(12):2208-22
Sarkar C et al
2014/01/01
Application: IHC PubMed
20 Xu X et al. Autophagy is essential for effector CD8(+) T cell survival and memory formation. Nat. Immunol. 2014 Dec;15(12):1152-61
Xu X et al
2014/01/01
Application: WB PubMed
21 Dunlop EA et al. FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation. Autophagy 2014 Oct;10(10):1749-60
Dunlop EA et al
2014/01/01
PubMed
22 Lim YM et al. Systemic autophagy insufficiency compromises adaptation to metabolic stress and facilitates progression from obesity to diabetes. Nat Commun 2014;5:4934
Lim YM et al
2014/01/01
PubMed
23 Kageyama S et al. Proteasome dysfunction activates autophagy and the Keap1-Nrf2 pathway. J. Biol. Chem. 2014 Sep;289(36):24944-55
Kageyama S et al
2014/01/01
PubMed
24 Hernandez ED et al. A macrophage NBR1-MEKK3 complex triggers JNK-mediated adipose tissue inflammation in obesity. Cell Metab. 2014 Sep;20(3):499-511
Hernandez ED et al
2014/01/01
PubMed
25 Rivera JF et al. Autophagy defends pancreatic &#x3B2; cells from human islet amyloid polypeptide-induced toxicity. J. Clin. Invest. 2014 Aug;124(8):3489-500
Rivera JF et al
2014/01/01
PubMed
26 Cottam EM et al. Coronavirus NSP6 restricts autophagosome expansion. Autophagy 2014 Aug;10(8):1426-41
Cottam EM et al
2014/01/01
Application: WB PubMed
27 Gaband辿-Rodr鱈guez E et al. High sphingomyelin levels induce lysosomal damage and autophagy dysfunction in Niemann Pick disease type A. Cell Death Differ. 2014 Jun;21(6):864-75
Gaband辿-Rodr鱈guez E et al
2014/01/01
PubMed
28 Nicot AS et al. Phosphorylation of NBR1 by GSK3 modulates protein aggregation. Autophagy 2014 Jun;10(6):1036-53
Nicot AS et al
2014/01/01
PubMed
29 Heijnen HF et al. Ribosomal protein mutations induce autophagy through S6 kinase inhibition of the insulin pathway. PLoS Genet. 2014;10(5):e1004371
Heijnen HF et al
2014/01/01
Application: WB PubMed
30 Kinsey C et al. Plac8 links oncogenic mutations to regulation of autophagy and is critical to pancreatic cancer progression. Cell Rep 2014 May;7(4):1143-55
Kinsey C et al
2014/01/01
PubMed
31 Guan BJ et al. Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2&#x3B1;. J. Biol. Chem. 2014 May;289(18):12593-611
Guan BJ et al
2014/01/01
PubMed
32 Kondratskyi A et al. Identification of ML-9 as a lysosomotropic agent targeting autophagy and cell death. Cell Death Dis 2014;5:e1193
Kondratskyi A et al
2014/01/01
PubMed
33 Ost M et al. Activation of AMPK&#x3B1;2 is not crucial for mitochondrial uncoupling-induced metabolic effects but required to maintain skeletal muscle integrity. PLoS ONE 2014;9(4):e94689
Ost M et al
2014/01/01
Application: WB PubMed
34 Karlsson AB et al. The role of spartin and its novel ubiquitin binding region in DALIS occurrence. Mol. Biol. Cell 2014 Apr;25(8):1355-65
Karlsson AB et al
2014/01/01
PubMed
35 Furuya N et al. PARK2/Parkin-mediated mitochondrial clearance contributes to proteasome activation during slow-twitch muscle atrophy via NFE2L1 nuclear translocation. Autophagy 2014 Apr;10(4):631-41
Furuya N et al
2014/01/01
PubMed
36 Zhang L et al. HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress. Nat Commun 2014;5:3430
Zhang L et al
2014/01/01
Application: WB, IHC PubMed
37 Sahani MH et al. Expression of the autophagy substrate SQSTM1/p62 is restored during prolonged starvation depending on transcriptional upregulation and autophagy-derived amino acids. Autophagy 2014 Mar;10(3):431-41
Sahani MH et al
2014/01/01
PubMed
38 Yamanaka T et al. NF-Y inactivation causes atypical neurodegeneration characterized by ubiquitin and p62 accumulation and endoplasmic reticulum disorganization. Nat Commun 2014;5:3354
Yamanaka T et al
2014/01/01
PubMed
39 Tanaka K et al. A novel acylaminoimidazole derivative, WN1316, alleviates disease progression via suppression of glial inflammation in ALS mouse model. PLoS ONE 2014;9(1):e87728
Tanaka K et al
2014/01/01
PubMed
40 Ricketts T et al. A nonsense mutation in mouse Tardbp affects TDP43 alternative splicing activity and causes limb-clasping and body tone defects. PLoS ONE 2014;9(1):e85962
Ricketts T et al
2014/01/01
PubMed
41 Khan MM et al. Role of autophagy, SQSTM1, SH3GLB1, and TRIM63 in the turnover of nicotinic acetylcholine receptors. Autophagy 2014 Jan;10(1):123-36
Khan MM et al
2014/01/01
PubMed
42 Yuan HX et al. Regulation of PIK3C3/VPS34 complexes by MTOR in nutrient stress-induced autophagy. Autophagy 2013 Dec;9(12):1983-95
Yuan HX et al
2013/01/01
PubMed
43 Adolph TE et al. Paneth cells as a site of origin for intestinal inflammation. Nature 2013 Nov;503(7475):272-6
Adolph TE et al
2013/01/01
PubMed
44 Ichimura Y et al. Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy. Mol. Cell 2013 Sep;51(5):618-31
Ichimura Y et al
2013/01/01
PubMed
45 Kondylis V et al. Endosome-mediated autophagy: an unconventional MIIC-driven autophagic pathway operational in dendritic cells. Autophagy 2013 Jun;9(6):861-80
Kondylis V et al
2013/01/01
PubMed
46 Ozcelik S et al. Rapamycin attenuates the progression of tau pathology in P301S tau transgenic mice. PLoS ONE 2013;8(5):e62459
Ozcelik S et al
2013/01/01
Application: WB PubMed
47 Raina K et al. Energy deprivation by silibinin in colorectal cancer cells: a double-edged sword targeting both apoptotic and autophagic machineries. Autophagy 2013 May;9(5):697-713
Raina K et al
2013/01/01
Application: IHC PubMed
48 Bechtel W et al. Vps34 deficiency reveals the importance of endocytosis for podocyte homeostasis. J. Am. Soc. Nephrol. 2013 Apr;24(5):727-43
Bechtel W et al
2013/01/01
PubMed
49 Warr MR et al. FOXO3A directs a protective autophagy program in haematopoietic stem cells. Nature 2013 Feb;494(7437):323-7
Warr MR et al
2013/01/01
Application: FC/FACS PubMed
50 Shackelford DB et al. LKB1 inactivation dictates therapeutic response of non-small cell lung cancer to the metabolism drug phenformin. Cancer Cell 2013 Feb;23(2):143-58
Shackelford DB et al
2013/01/01
PubMed
51 Jiang S et al. Heavy metal scavenger metallothionein mitigates deep hypothermia-induced myocardial contractile anomalies: role of autophagy. Am. J. Physiol. Endocrinol. Metab. 2013 Jan;304(1):E74-86
Jiang S et al
2013/01/01
PubMed
52 Schober A et al. Cell loss and autophagy in the extra-adrenal chromaffin organ of Zuckerkandl are regulated by glucocorticoid signalling. J. Neuroendocrinol. 2013 Jan;25(1):34-47
Schober A et al
2013/01/01
Application: IHC PubMed
53 Shiba-Fukushima K et al. PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy. Sci Rep 2012;2:1002
Shiba-Fukushima K et al
2012/01/01
PubMed
54 Chakrabarti A et al. RNase L Triggers Autophagy in Response to Viral Infections. J. Virol. 2012 Oct;86(20):11311-21
Chakrabarti A et al
2012/01/01
PubMed
55 Nascimbeni AC et al. The role of autophagy in the pathogenesis of glycogen storage disease type II (GSDII). Cell Death Differ. 2012 Oct;19(10):1698-708
Nascimbeni AC et al
2012/01/01
Application: WB PubMed
56 Stingele S et al. Global analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells. Mol. Syst. Biol. 2012;8:608
Stingele S et al
2012/01/01
PubMed
57 Chong A et al. Cytosolic clearance of replication-deficient mutants reveals Francisella tularensis interactions with the autophagic pathway. Autophagy 2012 Sep;8(9):1342-56
Chong A et al
2012/01/01
PubMed
58 Taguchi K et al. Keap1 degradation by autophagy for the maintenance of redox homeostasis. Proc. Natl. Acad. Sci. U.S.A. 2012 Aug;109(34):13561-6
Taguchi K et al
2012/01/01
PubMed
59 Fang J et al. Cytotoxic effects of bortezomib in myelodysplastic syndrome/acute myeloid leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and repression of PSMA1. Blood 2012 Jul;120(4):858-67
Fang J et al
2012/01/01
Species: Human, Application: WB PubMed
60 Uchida A et al. Non-human primate model of amyotrophic lateral sclerosis with cytoplasmic mislocalization of TDP-43. Brain 2012 Mar;135(Pt 3):833-46
Uchida A et al
2012/01/01
PubMed
61 Ghazi-Noori S et al. Progressive neuronal inclusion formation and axonal degeneration in CHMP2B mutant transgenic mice. Brain 2012 Mar;135(Pt 3):819-32
Ghazi-Noori S et al
2012/01/01
PubMed
62 Velikkakath AK et al. Mammalian Atg2 proteins are essential for autophagosome formation and important for regulation of size and distribution of lipid droplets. Mol. Biol. Cell 2012 Mar;23(5):896-909
Velikkakath AK et al
2012/01/01
PubMed
63 Cottam EM et al. Coronavirus nsp6 proteins generate autophagosomes from the endoplasmic reticulum via an omegasome intermediate. Autophagy 2011 Nov;7(11):1335-47
Cottam EM et al
2011/01/01
PubMed
64 Pattison JS et al. Atg7 induces basal autophagy and rescues autophagic deficiency in CryABR120G cardiomyocytes. Circ. Res. 2011 Jul;109(2):151-60
Pattison JS et al
2011/01/01
Application: WB PubMed
65 Rivera JF et al. Human-IAPP disrupts the autophagy/lysosomal pathway in pancreatic &#x3B2;-cells: protective role of p62-positive cytoplasmic inclusions. Cell Death Differ. 2011 Mar;18(3):415-26
Rivera JF et al
2011/01/01
PubMed
66 Itakura E et al. p62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding. J. Cell Biol. 2011 Jan;192(1):17-27
Itakura E et al
2011/01/01
Application: ICC PubMed
67 Narendra D et al. p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both. Autophagy 2010 Nov;6(8):1090-106
Narendra D et al
2010/01/01
Application: ICC PubMed
68 Aishima S et al. p62+ Hyaline inclusions in intrahepatic cholangiocarcinoma associated with viral hepatitis or alcoholic liver disease. Am. J. Clin. Pathol. 2010 Sep;134(3):457-65
Aishima S et al
2010/01/01
Application: IHC PubMed
69 Itakura E et al. Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins. Autophagy 2010 Aug;6(6):764-76
Itakura E et al
2010/01/01
PubMed
70 Spilman P et al. Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer&quot;s disease. PLoS ONE 2010;5(4):e9979
Spilman P et al
2010/01/01
PubMed
71 Hartleben B et al. Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice. J. Clin. Invest. 2010 Apr;120(4):1084-96
Hartleben B et al
2010/01/01
Application: WB PubMed
72 Lee IH et al. Regulation of autophagy by the p300 acetyltransferase. J. Biol. Chem. 2009 Mar;284(10):6322-8
Lee IH et al
2009/01/01
PubMed
73 Bj淡rk淡y G et al. Monitoring autophagic degradation of p62/SQSTM1. Meth. Enzymol. 2009;452:181-97
Bj淡rk淡y G et al
2009/01/01
PubMed
74 Kuusisto E et al. Use of p62/SQSTM1 antibodies for neuropathological diagnosis. Neuropathol. Appl. Neurobiol. 2008 Apr;34(2):169-80
Kuusisto E et al
2008/01/01
PubMed
75 Janig E et al. Interaction of stress proteins with misfolded keratins. Eur. J. Cell Biol. 2005 Mar;84(2-3):329-39
Janig E et al
2005/01/01
PubMed
76 M端ller T et al. Immunohistochemical analysis of Mallory bodies in Wilsonian and non-Wilsonian hepatic copper toxicosis. Hepatology 2004 Apr;39(4):963-9
M端ller T et al
2004/01/01
PubMed
77 Furukawa Y et al. Ubiquitin and ubiquitin-related proteins in neurons and dendrites of brains of atypical Pick&quot;s disease without Pick bodies. Neuropathology 2004 Mar;24(1):38-45
Furukawa Y et al
2004/01/01
PubMed
78 Arai T et al. Neuronal and glial inclusions in frontotemporal dementia with or without motor neuron disease are immunopositive for p62. Neurosci. Lett. 2003 May;342(1-2):41-4
Arai T et al
2003/01/01
PubMed
79 Kuusisto E et al. Early accumulation of p62 in neurofibrillary tangles in Alzheimer&quot;s disease: possible role in tangle formation. Neuropathol. Appl. Neurobiol. 2002 Jun;28(3):228-37
Kuusisto E et al
2002/01/01
PubMed
80 Stumptner C et al. Mallory body--a disease-associated type of sequestosome. Hepatology 2002 May;35(5):1053-62
Stumptner C et al
2002/01/01
PubMed
81 Zatloukal K et al. p62 Is a common component of cytoplasmic inclusions in protein aggregation diseases. Am. J. Pathol. 2002 Jan;160(1):255-63
Zatloukal K et al
2002/01/01
PubMed
82 Stumptner C et al. Analysis of intracytoplasmic hyaline bodies in a hepatocellular carcinoma. Demonstration of p62 as major constituent. Am. J. Pathol. 1999 Jun;154(6):1701-10
Stumptner C et al
1999/01/01
PubMed
83 Santanam U et al. Atg7 cooperates with Pten loss to drive prostate cancer tumor growth. Genes Dev. 2016 Feb;30(4):399-407
Santanam U et al
2016/01/01
PubMed
84 Sergin I et al. Inclusion bodies enriched for p62 and polyubiquitinated proteins in macrophages protect against atherosclerosis. Sci Signal 2016 Jan;9(409):ra2
Sergin I et al
2016/01/01
PubMed
85 Starheim KK et al. Intracellular glutathione determines bortezomib cytotoxicity in multiple myeloma cells. Blood Cancer J 2016 Jul;6(7):e446
Starheim KK et al
2016/01/01
PubMed
86 Yamanaka T et al. Differential roles of NF-Y transcription factor in ER chaperone expression and neuronal maintenance in the CNS. Sci Rep 2016 Sep;6:34575
Yamanaka T et al
2016/01/01
PubMed
87 Lim SW et al. Effect of Exendin-4 on Autophagy Clearance in Beta Cell of Rats with Tacrolimus-induced Diabetes Mellitus. Sci Rep 2016 Jul;6:29921
Lim SW et al
2016/01/01
PubMed
88 Angelini C et al. Lipolysis and lipophagy in lipid storage myopathies. Biochim. Biophys. Acta 2016 Jul;1862(7):1367-73
Angelini C et al
2016/01/01
PubMed
89 Corcelle-Termeau E et al. Excess sphingomyelin disturbs ATG9A trafficking and autophagosome closure. Autophagy 2016 May;12(5):833-49
Corcelle-Termeau E et al
2016/01/01
PubMed
90 Ra EA et al. TRIM31 promotes Atg5/Atg7-independent autophagy in intestinal cells. Nat Commun 2016 May;7:11726
Ra EA et al
2016/01/01
PubMed
91 Kaizuka T et al. Atg13 Is Essential for Autophagy and Cardiac Development in Mice. Mol. Cell. Biol. 2015 Dec;36(4):585-95
Kaizuka T et al
2015/01/01
PubMed
92 Saito T et al. p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming. Nat Commun 2016 Jun;7:12030
Saito T et al
2016/01/01
PubMed
93 Jarvela TS et al. The neural chaperone proSAAS blocks &#x3B1;-synuclein fibrillation and neurotoxicity. Proc. Natl. Acad. Sci. U.S.A. 2016 08;113(32):E4708-15
Jarvela TS et al
2016/01/01
PubMed
94 Weder N et al. Child abuse, depression, and methylation in genes involved with stress, neural plasticity, and brain circuitry. J Am Acad Child Adolesc Psychiatry 2014 Apr;53(4):417-24.e5
Weder N et al
2014/01/01
PubMed
95 Klionsky DJ et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 2016;12(1):1-222
Klionsky DJ et al
2016/01/01
PubMed
96 Zhang J et al. A Founder Mutation in VPS11 Causes an Autosomal Recessive Leukoencephalopathy Linked to Autophagic Defects. PLoS Genet. 2016 Apr;12(4):e1005848
Zhang J et al
2016/01/01
PubMed
97 Kenific CM et al. NBR1 enables autophagy-dependent focal adhesion turnover. J. Cell Biol. 2016 Feb;212(5):577-90
Kenific CM et al
2016/01/01
PubMed
98 Taneike M et al. mTOR Hyperactivation by Ablation of Tuberous Sclerosis Complex 2 in the Mouse Heart Induces Cardiac Dysfunction with the Increased Number of Small Mitochondria Mediated through the Down-Regulation of Autophagy. PLoS ONE 2016;11(3):e015262
Taneike M et al
2016/01/01
PubMed
99 Lenoir O et al. Endothelial cell and podocyte autophagy synergistically protect from diabetes-induced glomerulosclerosis. Autophagy 2015;11(7):1130-45
Lenoir O et al
2015/01/01
PubMed
100 Larroquette F et al. Vapb/Amyotrophic lateral sclerosis 8 knock-in mice display slowly progressive motor behavior defects accompanying ER stress and autophagic response. Hum. Mol. Genet. 2015 Nov;24(22):6515-29
Larroquette F et al
2015/01/01
PubMed
101 Hieke N et al. Expression of a ULK1/2 binding-deficient ATG13 variant can partially restore autophagic activity in ATG13-deficient cells. Autophagy 2015;11(9):1471-83
Hieke N et al
2015/01/01
PubMed
102 Zhou Z et al. Autophagy supports color vision. Autophagy 2015;11(10):1821-32
Zhou Z et al
2015/01/01
PubMed
103 Ciuffa R et al. The selective autophagy receptor p62 forms a flexible filamentous helical scaffold. Cell Rep 2015 May;11(5):748-58
Ciuffa R et al
2015/01/01
PubMed
104 Ulbricht A et al. Induction and adaptation of chaperone-assisted selective autophagy CASA in response to resistance exercise in human skeletal muscle. Autophagy 2015 Mar;11(3):538-546
Ulbricht A et al
2015/01/01
PubMed
105 Chandrachud U et al. Unbiased Cell-based Screening in a Neuronal Cell Model of Batten Disease Highlights an Interaction between Ca2+ Homeostasis, Autophagy, and CLN3 Protein Function. J. Biol. Chem. 2015 Jun;290(23):14361-80
Chandrachud U et al
2015/01/01
PubMed
106 Johansson I et al. The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells. Autophagy 2015;11(9):1636-51
Johansson I et al
2015/01/01
PubMed
107 Lodder J et al. Macrophage autophagy protects against liver fibrosis in mice. Autophagy 2015;11(8):1280-92
Lodder J et al
2015/01/01
PubMed
108 Costes S et al. UCHL1 deficiency exacerbates human islet amyloid polypeptide toxicity in &#x3B2;-cells: evidence of interplay between the ubiquitin/proteasome system and autophagy. Autophagy 2014 Jun;10(6):1004-14
Costes S et al
2014/01/01
PubMed
109 Zatloukal B et al. Sensitivity and specificity of in situ proximity ligation for protein interaction analysis in a model of steatohepatitis with Mallory-Denk bodies. PLoS ONE 2014;9(5):e96690
Zatloukal B et al
2014/01/01
PubMed
110 Yamano K et al. PINK1 is degraded through the N-end rule pathway. Autophagy 2013 Nov;9(11):1758-69
Yamano K et al
2013/01/01
PubMed
111 Hoshino A et al. Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart. Nat Commun 2013 Aug;4:2308
Hoshino A et al
2013/01/01
PubMed
112 Liu S et al. Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury. Autophagy 2012 May;8(5):826-37
Liu S et al
2012/01/01
PubMed
113 Germain M et al. MCL-1 is a stress sensor that regulates autophagy in a developmentally regulated manner. EMBO J. 2011 Jan;30(2):395-407
Germain M et al
2011/01/01
PubMed
114 Saiki S et al. Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition. Autophagy 2011 Feb;7(2):176-87
Saiki S et al
2011/01/01
PubMed
115 Taneike M et al. Inhibition of autophagy in the heart induces age-related cardiomyopathy. Autophagy 2010 Jul;6(5):600-6
Taneike M et al
2010/01/01
PubMed
116 Masiero E et al. Autophagy is required to maintain muscle mass. Cell Metab. 2009 Dec;10(6):507-15
Masiero E et al
2009/01/01
PubMed
117 Mizushima N et al. How to interpret LC3 immunoblotting. Autophagy ;3(6):542-5
Mizushima N et al
PubMed
118 Mildenberger J et al. N-3 PUFAs induce inflammatory tolerance by formation of KEAP1-containing SQSTM1/p62-bodies and activation of NFE2L2. Autophagy 2017 Oct;13(10):1664-1678
Mildenberger J et al
2017/01/01
PubMed
119 Jacquier A et al. Cryptic amyloidogenic elements in mutant NEFH causing Charcot-Marie-Tooth 2 trigger aggresome formation and neuronal death. Acta Neuropathol Commun 2017 Jul;5(1):55
Jacquier A et al
2017/01/01
PubMed
120 Joachim J et al. Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy. Curr. Biol. 2017 Jul;27(14):2123-2136.e7
Joachim J et al
2017/01/01
PubMed
121 Sergin I et al. Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis. Nat Commun 2017 Jun;8:15750
Sergin I et al
2017/01/01
PubMed
122 Lee MY et al. Peroxisomal protein PEX13 functions in selective autophagy. EMBO Rep. 2017 Jan;18(1):48-60
Lee MY et al
2017/01/01
PubMed
123 Nascimbeni AC et al. Autophagy dysregulation in Danon disease. Cell Death Dis 2017 Jan;8(1):e2565
Nascimbeni AC et al
2017/01/01
PubMed
124 Ruf S et al. PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy. Autophagy 2017 Mar;13(3):486-505
Ruf S et al
2017/01/01
PubMed
125 Aas A et al. Nucleocytoplasmic Shuttling of FTO Does Not Affect Starvation-Induced Autophagy. PLoS ONE 2017;12(3):e0168182
Aas A et al
2017/01/01
PubMed
126 Fajardo VA et al. Sarcolipin deletion exacerbates soleus muscle atrophy and weakness in phospholamban overexpressing mice. PLoS ONE 2017;12(3):e0173708
Fajardo VA et al
2017/01/01
PubMed
127 Feldmann A et al. The RAB GTPase RAB18 modulates macroautophagy and proteostasis. Biochem. Biophys. Res. Commun. 2017 05;486(3):738-743
Feldmann A et al
2017/01/01
PubMed
128 Duleh S et al. Activation of the Keap1/Nrf2 stress response pathway in autophagic vacuolar myopathies. Acta Neuropathol Commun 2016 Oct;4(1):115
Duleh S et al
2016/01/01
PubMed
129 Feldmann, A. et al. The RAB GTPase RAB18 modulates macroautophagy and proteostasis. Biochem. Biophys. Res. Commun. 486, 738-743 (2017).

species: human, application: WB, IHC (frozen) PubMed
130 Fajardo, V. A. et al. Sarcolipin deletion exacerbates soleus muscle atrophy and weakness in phospholamban overexpressing mice. PLoS One 12, e0173708 (2017).

species: mouse, application: WB PubMed
131 Aas, A. et al. Nucleocytoplasmic Shuttling of FTO Does Not Affect Starvation-Induced Autophagy. PLoS One 12, e0168182 (2017).

species: mouse, application: WB PubMed
132 Ruf, S. et al. PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy. Autophagy 13, 486-505 (2017).

species: human, application: ICC-IF PubMed
133 Nascimbeni, A. C., Fanin, M., Angelini, C. and Sandri, M. Autophagy dysregulation in Danon disease. Cell Death Dis. 8, e2565 (2017).

species: human, application: WB, IHC (frozen) PubMed
134 Lee, M. Y. et al. Peroxisomal protein PEX13 functions in selective autophagy. EMBO Rep. 18, 48-60 (2017).

species: mouse, application: WB PubMed
135 Sergin, I. et al. Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis. Nat. Commun. 8, 15750 (2017).

species: human, mouse, application: WB, IHC (frozen), ICC-IF PubMed
136 Joachim, J. et al. Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy. Curr. Biol. 27, 2123-2136.e7 (2017).

species: human, application: ICC-IF PubMed
137 Jacquier, A. et al. Cryptic amyloidogenic elements in mutant NEFH causing Charcot-Marie-Tooth 2 trigger aggresome formation and neuronal death. Acta Neuropathol. Commun. 5, 55 (2017).

species: human, chicken, application: IHC (frozen), ICC-IF PubMed
138 Mildenberger, J. et al. N-3 PUFAs induce inflammatory tolerance by formation of KEAP1-containing SQSTM1/p62-bodies and activation of NFE2L2. Autophagy 00-00 (2017).

species: human, mouse, application: WB, ICC-IF PubMed
139 Duleh, S., Wang, X., Komirenko, A. and Margeta, M. Activation of the Keap1/Nrf2 stress response pathway in autophagic vacuolar myopathies. Acta Neuropathol. Commun. 4, 115 (2016).

species: human, mouse, application: WB, IHC (frozen) PubMed
140 Santanam, U. et al. Atg7 cooperates with Pten loss to drive prostate cancer tumor growth. Genes Dev. 30, 399-407 (2016).

species: mouse, application: IHC (frozen), ICC-IF PubMed
141 Starheim, K. et al. Intracellular glutathione determines borte. cytotoxicity in multiple myeloma cells. Blood Cancer J. 6, (2016).

species: human, application: WB PubMed
142 Yamanaka, T. et al. Differential roles of NF-Y transcription factor in ER chaperone expression and neuronal maintenance in the CNS. Nat. Publ. Gr. 6, (2016).

species: mouse, application: WB, IHC (frozen) PubMed
143 Lim, S. W., Jin, L., Jin, J. and Yang, C. W. Effect of Exendin-4 on Autophagy Clearance in Beta Cell of Rats with Tacrolimus-induced Diabetes Mellitus. Nat. Publ. Gr. 6, (2016).

species: rat, application: WB, IHC (paraffin) PubMed
144 Angelini, C., Nascimbeni, A. C., Cenacchi, G. and Tasca, E. Lipolysis and lipophagy in lipid storage myopathies. Biochim. Biophys. Acta 1367-1373 (2016).

species: human, application: WB, IHC (frozen) PubMed
145 Corcelle-Termeau, E. et al. Excess sphingomyelin disturbs ATG9A trafficking and autophagosome closure. Autophagy 12, 533-849 (2016).

species: mouse, application: WB PubMed
146 Ra, E. A. et al. TRIM31 promotes Atg5/Atg7-independent autophagy in intestinal cells. Nat. Commun. 7, (2016).

species: human, application: WB PubMed
147 Kaizuka, T. and Mizushima, N. Atg13 Is Essential for Autophagy and Cardiac Development in Mice. Mol. Cell. Biol. 36, 585-595 (2016).

species: mouse, application: WB, ICC-IF PubMed
148 Saito, T. et al. p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming. Nat. Commun. 7, (2016).

species: human, mouse, application: WB, IHC (paraffin) PubMed
149 Jarvela, T. S. et al. The neural chaperone proSAAS blocks ホア-synuclein fibrillation and neurotoxicity. Proc. Natl. Acad. Sci. U. S. A. (2016).

species: human, application: IHC (frozen) PubMed
150 Puvirajesinghe, T. M. et al. Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer. Nat. Commun. 7, (2016).

species: human, mouse, application: WB, ICC-IF PubMed
151 Salas, E., Roy, S., Marsh, T., Rubin, B. and Debnath, J. Oxidative Pentose Phosphate Pathway Inhibition Is A Key Determinant of Antimalarial Induced Cancer Cell Death. Oncogene 35, 2913-2922 (2016).

species: mouse, application: ICC-IF PubMed
152 Klionsky, D. J. et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12, 1 (2016).

species: mouse, application: WB PubMed
153 Taneike, M. et al. mTOR Hyperactivation by Ablation of Tuberous Sclerosis Complex 2 in the Mouse Heart Induces Cardiac Dysfunction with the Increased Number of Small Mitochondria Mediated through the Down-Regulation of Autophagy. PLoS One 11, (2016).

species: mouse, application: WB PubMed
154 Morimoto, D. et al. The unexpected role of polyubiquitin chains in the formation of fibrillar aggregates. Nat. Commun. 6, (2015).

species: mouse, application: WB, ICC-IF PubMed
155 Milan, E. et al. A plastic SQSTM1/p62-dependent autophagic reserve maintains proteostasis and determines proteasome inhibitor susceptibility in multiple myeloma cells. Autophagy 11, 1161-1178 (2015).

species: human, application: WB, ICC-IF PubMed
156 Larroquette, F. et al. Vapb/Amyotrophic lateral sclerosis 8 knock-in mice display slowly progressive motor behavior defects accompanying ER stress and autophagic response. Hum. Mol. Genet. 24, 6515-6529 (2015).

species: mouse, application: WB PubMed
157 Hieke, N. et al. Expression of a ULK1/2 binding-deficient ATG13 variant can partially restore autophagic activity in ATG13-deficient cells. Autophagy 11, 1471-1483 (2015).

species: mouse, application: WB, ICC-IF PubMed
158 Zhou, Z. et al. Autophagy supports color vision. Autophagy 11, 1821-1832 (2015).

species: mouse, application: IHC (frozen) PubMed
159 Ciuffa, R. et al. The selective autophagy receptor p62 forms a flexible filamentous helical scaffold. Cell Rep. 11, 748-58 (2015).

species: human, application: WB PubMed
160 Ulbricht, A. et al. Induction and adaptation of chaperone-assisted selective autophagy CASA in response to resistance exercise in human skeletal muscle. Autophagy 11, 538-546 (2015).

species: human, application: WB PubMed
161 Murrow, L., Malhotra, R. and Debnath, J. ATG12-ATG3 Interacts with Alix to Promote Basal Autophagic Flux and Late Endosome Function. Nat. Cell Biol. 17, 300-310 (2015).

species: mouse, application: WB PubMed
162 Lim, J. et al. Proteotoxic Stress Induces Phosphorylation of p62/SQSTM1 by ULK1 to Regulate Selective Autophagic Clearance of Protein Aggregates. PLoS One 11, (2015).

species: human, mouse, application: WB, ICC-IF PubMed
163 Felzen, V. et al. Estrogen receptor ホア regulates non-canonical autophagy that provides stress resistance to neuroblastoma and breast cancer cells and involves BAG3 function. Cell Death Dis. 6, (2015).

species: human, application: ICC-IF PubMed
164 Chandrachud, U. et al. Unbiased Cell-based Screening in a Neuronal Cell Model of Batten Disease Highlights an Interaction between Ca 2+ Homeostasis, Autophagy, and CLN3 Protein Function. J. Biol. Chem. 290, 14361-14380 (2015).

species: mouse, application: WB PubMed
165 Liu, S. et al. Disrupted autophagy after spinal cord injury is associated with ER stress and neuronal cell death. Cell Death Dis. 6, (2015).

species: rat, application: WB, IHC (frozen) PubMed
166 Johansson, I. et al. The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells. Autophagy 11, 1636-1651 (2015).

species: human, mouse, application: WB, ICC-IF PubMed
167 Lodder, J. et al. Macrophage autophagy protects against liver fibrosis in mice. Autophagy 11, 1280-1292 (2015).

species: mouse, application: ICC-IF PubMed
168 Agarwal, S. et al. Autophagy and endosomal trafficking inhibition by Vibrio cholerae MARTX toxin phosphatidylinositol- 3-phosphate-specific phospholipase A1 activity. Nat. Commun. 6, (2015).

species: human, application: WB PubMed
169 Akizu, N. et al. Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction HHS Public Access. Nat. Genet. 47, 528-534 (2015).

species: human, application: WB PubMed
170 Ruozi, G. et al. AAV-mediated in vivo functional selection of tissue-protective factors against ischaemia. Nat. Commun. 6, (2015).

species: mouse, application: WB PubMed
171 Arel-Dubeau, A.-M. et al. Cucurbitacin E Has Neuroprotective Properties and Autophagic Modulating Activities on Dopaminergic Neurons. Oxid. Med. Cell. Longev. 2014, 15 (2015).

species: rat, application: WB PubMed
172 Newton, P. T., Vuppalapati, K. K., Bouderlique, T. and Chagin, A. S. Pharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner. Autophagy 11, 1594-1607 (2015).

species: mouse, rat, application: WB PubMed
173 Shi, J. et al. NBR1 is dispensable for PARK2-mediated mitophagy regardless of the presence or absence of SQSTM1. Cell Death Dis. 6, (2015).

species: human, application: WB PubMed
174 Karlsson, A. B. et al. The role of spartin and its novel ubiquitin binding region in DALIS occurrence. Mol. Biol. Cell 25, 1355-1365 (2014).

species: mouse, application: ICC-IF PubMed
175 Kinsey, C. et al. Plac8 links oncogenic mutations to regulation of autophagy and is critical to pancreatic cancer progression. Cell Rep. 7, 1143-1155 (2014).

species: human, mouse, application: WB PubMed
176 McLendon, P. et al. An Unbiased High-Throughput Screen to Identify Novel Effectors That Impact on Cardiomyocyte Aggregate Levels. Circ.Res. 121, 604-616 (2017).

PubMed
177 Glatigny, M. et al. Autophagy Is Required for Memory Formation and Reverses Age-Related Memory Decline. Curr.Biol. 29, 435-448.e8 (2019)

PubMed
178 Gorgulu, K. et al. Levels of the Autophagy-Related 5 Protein Affect Progression and Metastasis of Pancreatic Tumors in Mice. Gastroenterology. 156, 203-217.e20 (2019)

PubMed
179 Lim, J. et al. Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins. Elife. 8, (2019)

PubMed
180 Lim, J. et al. Proteotoxic Stress Induces Phosphorylation of p62/SQSTM1 by ULK1 to Regulate Selective Autophagic Clearance of Protein Aggregates. PLoS One 11, (2015).

PubMed
181 Yamada, T. et al. Prevention and regression of megamitochondria and steatosis by blocking mitochondrial fusion in the liver. iScience 25, 103996 (2022).

PubMed
182 Gasset-Rosa, F. et al. Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death. Neuron. 102, 339-357.e7 (2019)

PubMed
183 Bonsi, P. et al. RGS9-2 rescues dopamine D2 receptor levels and signaling in DYT1 dystonia mouse models. EMBO.Mol.Med. 11, (2019)

PubMed
184 Yamanaka, T. et al. NF-Y inactivation causes atypical neurodegeneration characterized by ubiquitin and p62 accumulation and endoplasmic reticulum disorganization. Nat. Commun. 5, (2014).

PubMed
185 Yamano, K. & Youle, R. J. PINK1 is degraded through the N-end rule pathway. Autophagy 9, 1758–69 (2013).

PubMed
186 Hegdekar N et al. N-Acetyl-L-leucine improves functional recovery and attenuates cortical cell death and neuroinflammation after traumatic brain injury in mice. Sci Rep 2021 Apr;11(1):9249
Hegdekar N et al
2021/01/01
PubMed
187 Arel-Dubeau, A.-M. et al. Cucurbitacin E Has Neuroprotective Properties and Autophagic Modulating Activities on Dopaminergic Neurons. Oxid. Med. Cell. Longev. 2014, 15 (2015).

PubMed
188 Zhang, J. et al. Cross-regulation of defective endolysosome trafficking and enhanced autophagy through TFEB in UNC13D deficiency. Autophagy. , 1-19 (2019)

PubMed
189 Kessler, S. et al. Diethylnitrosamine (DENA) recapitulates formation of hepatic angiosarcoma in pigs. PLoS.One. 14, e0214756 (2019)

PubMed
190 Fucci C et al. The Interaction of the Tumor Suppressor FAM46C with p62 and FNDC3 Proteins Integrates Protein and Secretory Homeostasis. Cell Rep 2020 Sep;32(12):108162
Fucci C et al
2020/01/01
PubMed
191 Kivinen, N. The role of autophagy in age-related macular degeneration. Acta.Ophthalmol. 96 Suppl A110, Jan-50 (2018)

PubMed
192 Hieke, N. et al. Expression of a ULK1/2 binding-deficient ATG13 variant can partially restore autophagic activity in ATG13-deficient cells. Autophagy 11, 1471–1483 (2015).

PubMed
193 Metti S et al. The Polyphenol Pterostilbene Ameliorates the Myopathic Phenotype of Collagen VI Deficient Mice via Autophagy Induction. Front Cell Dev Biol 2020;8:580933
Metti S et al
2020/01/01
PubMed
194 Akizu, N. et al. Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction HHS Public Access. Nat. Genet. 47, 528–534 (2015).

PubMed
195 Shiba-Fukushima, K. et al. Evidence that phosphorylated ubiquitin signaling is involved in the etiology of Parkinson&quot;s disease. Hum.Mol.Genet. 26, 3172-3185 (2017)

PubMed
196 Yamanaka, T. et al. Differential roles of NF-Y transcription factor in ER chaperone expression and neuronal maintenance in the CNS. Nat. Publ. Gr. 6, (2016).

PubMed
197 Kiryu-Seo S et al. Impaired disassembly of the axon initial segment restricts mitochondrial entry into damaged axons. EMBO J 2022 Oct;41(20):e110486
Kiryu-Seo S et al
2022/01/01
PubMed
198 Shimozawa, A. et al. Propagation of pathological 留-synuclein in marmoset brain. Acta Neuropathol. Commun. 5, 12 (2017)

PubMed
199 Keller F et al. A Scaffold-Free 3-D Co-Culture Mimics the Major Features of the Reverse Warburg Effect In Vitro. Cells 2020 Aug;9(8)
Keller F et al
2020/01/01
PubMed
200 Osonoi, Y. et al. Defective autophagy in vascular smooth muscle cells enhances cell death and atherosclerosis. Autophagy. 14, 1991-2006 (2018)

PubMed
201 Rivera, J. F., Costes, S., Gurlo, T., Glabe, C. G. & Butler, P. C. Autophagy defends pancreatic β cells from human islet amyloid polypeptide-induced toxicity. J. Clin. Invest. 124, 3489–500 (2014).

PubMed
202 Milan, E. et al. A plastic SQSTM1/p62-dependent autophagic reserve maintains proteostasis and determines proteasome inhibitor susceptibility in multiple myeloma cells. Autophagy 11, 1161–1178 (2015).

PubMed
203 Mauthe, M. et al. Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion. Autophagy. 14, 1435-1455 (2018)

PubMed
204 Kataura, T. et al. NDP52 acts as a redox sensor in PINK1/Parkin‐mediated mitophagy. EMBO J. e111372 (2022).

PubMed
205 Rienzo, M. et al. Autophagy induction in atrophic muscle cells requires ULK1 activation by TRIM32 through unanchored K63-linked polyubiquitin chains. Sci.Adv. 5, eaau8857 (2019)

PubMed
206 Ozcelik, S. et al. Rapamycin Attenuates the Progression of Tau Pathology in P301S Tau Transgenic Mice. PLoS One 8, (2013)

PubMed
207 Sargent, D. et al. Neuronal VPS35 deletion induces spinal cord motor neuron degeneration and early post-natal lethality . Brain Commun. 3, 1–20 (2021).

PubMed
208 Eino, A. et al. Sqstm1-GFP knock-in mice reveal dynamic actions of Sqstm1 during autophagy and under stress conditions in living cells. J. Cell Sci. 128, 4453–61 (2015).

PubMed
209 Deng, Z. et al. ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway. Autophagy. 16, 917-931 (2020)

PubMed
210 Guan, B.-J. et al. Translational Control during Endoplasmic Reticulum Stress beyond Phosphorylation of the Translation Initiation Factor eIF2␣ *. J. Biol. Chem. 289, 12593–12611 (2014).

PubMed
211 S叩nchez-L坦pez, E. et al. Choline Uptake and Metabolism Modulate Macrophage IL-1硫 and IL-18 Production. Cell.Metab. 29, 1350-1362.e7 (2019)

PubMed
212 Horigome, Y. et al. Loss of autophagy in chondrocytes causes severe growth retardation. Autophagy. , 1-11 (2019)

PubMed
213 Jiang, S., Guo, R., Zhang, Y., Zou, Y. & Ren, J. Heavy metal scavenger metallothionein mitigates deep hypothermia-induced myocardial contractile anomalies: role of autophagy. Am. J. Physiol. - Endocrinol. Metab. 304, (2013).

PubMed
214 Kageyama, S. et al. Negative regulation of the Keap1-Nrf2 pathway by a p62/Sqstm1 splicing variant. Mol.Cell.Biol. ,  (2018).

PubMed
215 Javaheri, A. et al. TFEB activation in macrophages attenuates postmyocardial infarction ventricular dysfunction independently of ATG5-mediated autophagy. JCI.Insight. 4, (2019)

PubMed
216 Wallot-Hieke, N. et al. Systematic analysis of ATG13 domain requirements for autophagy induction. Autophagy. , 1-58 (2017)

PubMed
217 Hill, C. et al. Autophagy inhibition-mediated epithelial-mesenchymal transition augments local myofibroblast differentiation in pulmonary fibrosis. Cell.Death.Dis. 10, 591 (2019)

PubMed
218 G坦mez-Sintes, R. et al. Standard Assays for the Study of Autophagy in the Ex Vivo Retina. Cells. 6, (2017)

PubMed
219 Kinsey, C. et al. Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers. Nat.Med. 25, 620-627 (2019)

PubMed
220 Furuya, N. et al. PARK2/Parkin-mediated mitochondrial clearance contributes to proteasome activation during slow-twitch muscle atrophy via NFE2L1 nuclear translocation. Autophagy 10, 631–41 (2014).

PubMed
221 Kaizuka, T. & Mizushima, N. Atg13 Is Essential for Autophagy and Cardiac Development in Mice. Mol. Cell. Biol. 36, 585–595 (2016).

PubMed
222 Kinsey, C. et al. Plac8 links oncogenic mutations to regulation of autophagy and is critical to pancreatic cancer progression. Cell Rep. 7, 1143–1155 (2014).

PubMed
223 Santanam, U. et al. Atg7 cooperates with Pten loss to drive prostate cancer tumor growth. Genes Dev. 30, 399–407 (2016).

PubMed
224 Noman, M. et al. Inhibition of Vps34 reprograms cold into hot inflamed tumors and improves anti-PD-1/PD-L1 immunotherapy. Sci.Adv. 6, eaax7881 (2020)

PubMed
225 Kurashige, T. et al. Hormonal Regulation of Autophagy in Thyroid PCCL3 Cells and the Thyroids of Male Mice. J.Endocr.Soc. 4, bvaa054 (2020)

PubMed
226 Newton, P. T., Vuppalapati, K. K., Bouderlique, T. & Chagin, A. S. Pharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner. Autophagy 11, 1594–1607 (2015).

PubMed
227 Ciuffa, R. et al. The selective autophagy receptor p62 forms a flexible filamentous helical scaffold. Cell Rep. 11, 748–58 (2015).

PubMed
228 Nascimbeni, A. C., Fanin, M., Angelini, C. & Sandri, M. Autophagy dysregulation in Danon disease. Cell Death Dis. 8, e2565 (2017).

PubMed
229 Sebori, R. et al. Resveratrol Decreases Oxidative Stress by Restoring Mitophagy and Improves the Pathophysiology of Dystrophin-Deficient mdx Mice. Oxid.Med.Cell.Longev. 2018, 9179270 (2018).

PubMed
230 Nwadike, C. et al. AMPK Inhibits ULK1-Dependent Autophagosome Formation and Lysosomal Acidification via Distinct Mechanisms. Mol.Cell.Biol. 38,  (2018).

PubMed
231 Angelini, C., Nascimbeni, A. C., Cenacchi, G. & Tasca, E. Lipolysis and lipophagy in lipid storage myopathies. Biochim. Biophys. Acta 1367–1373 (2016).

PubMed
232 Pellegrini, C. et al. All-trans retinoic acid and rapamycin normalize Hutchinson Gilford progeria fibroblast phenotype. Oncotarget 6, 29914–29928 (2015).

PubMed
233 Manzetti J et al. BK Polyomavirus Evades Innate Immune Sensing by Disrupting the Mitochondrial Network and Promotes Mitophagy. iScience 2020 Jul;23(7):101257
Manzetti J et al
2020/01/01
PubMed
234 Aron, R. et al. Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington&quot;s disease. Nat.Commun. 9, 3191 (2018).

PubMed
235 Schwob, A. et al. SQSTM-1/p62 potentiates HTLV-1 Tax-mediated NF-虜B activation through its ubiquitin binding function. Sci.Rep. 9, 16014 (2019)

PubMed
236 Lim, Y.-M. et al. Systemic autophagy insufficiency compromises adaptation to metabolic stress and facilitates progression from obesity to diabetes. Nat. Commun. 5, (2014).

PubMed
237 Battista, R. et al. Autophagy mediates epithelial cancer chemoresistance by reducing p62/SQSTM1 accumulation. PLoS.One. 13, e0201621 (2018).

PubMed
238 Nam, S. et al. Autophagy attenuates tubulointerstital fibrosis through regulating transforming growth factor-硫 and NLRP3 inflammasome signaling pathway. Cell.Death.Dis. 10, 78 (2019)

PubMed
239 Saito, T. et al. Autophagy regulates lipid metabolism through selective turnover of NCoR1. Nat.Commun. 10, 1567 (2019)

PubMed
240 Johansson, I. et al. The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells. Autophagy 11, 1636–1651 (2015).

PubMed
241 Heijnen, H. F. et al. Ribosomal Protein Mutations Induce Autophagy through S6 Kinase Inhibition of the Insulin Pathway. PLoS Genet. 10, (2014).

PubMed
242 Sample, A. et al. Adaptor protein p62 promotes skin tumor growth and metastasis and is induced by UVA radiation. J.Biol.Chem. 292, 14786-14795 (2017).

PubMed
243 Gallagher, L. et al. Lysosomotropism depends on glucose: a chloroquine resistance mechanism. Cell.Death.Dis. 8, e3014 (2017).

PubMed
244 Aubert, P. et al. Maternal protein restriction induces gastrointestinal dysfunction and enteric nervous system remodeling in rat offspring. FASEB.J. 33, 770-781 (2019)

PubMed
245 Yang, Y. et al. Cytoplasmic DAXX drives SQSTM1/p62 phase condensation to activate Nrf2-mediated stress response. Nat.Commun. 10, 3759 (2019)

PubMed
246 Jackson, J. et al. SGPL1 stimulates VPS39 recruitment to the mitochondria in MICU1 deficient cells. Mol. Metab. 61, 101503 (2022).

PubMed
247 Sarkar, C. et al. PLA2G4A/cPLA2-mediated lysosomal membrane damage leads to inhibition of autophagy and neurodegeneration after brain trauma. Autophagy. , 1-20 (2019)

PubMed
248 Conte, A. et al. High mobility group A1 protein modulates autophagy in cancer cells. Cell.Death.Differ. 24, 1948-1962 (2017).

PubMed
249 Jung, S. et al. Buffering of cytosolic calcium plays a neuroprotective role by preserving the autophagy-lysosome pathway during MPP+-induced neuronal death. Cell.Death.Discov. 5, 130 (2019)

PubMed
250 Sergin, I. et al. Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis. Nat. Commun. 8, 15750 (2017).

PubMed
251 Miret-Casals, L. et al. Identification of New Activators of Mitochondrial Fusion Reveals a Link between Mitochondrial Morphology and Pyrimidine Metabolism. Cell.Chem.Biol. 25, 268-278.e4 (2018)

PubMed
252 Over奪, K. et al. TRIM32, but not its muscular dystrophy-associated mutant, positively regulates and is targeted to autophagic degradation by p62/SQSTM1. J.Cell.Sci. 132, (2019)

PubMed
253 Riemschoss, K. et al. Fibril-induced glutamine-/asparagine-rich prions recruit stress granule proteins in mammalian cells. Life.Sci.Alliance. 2, (2019)

PubMed
254 Kondylis, V. et al. Endosome-mediated autophagy: an unconventional MIIC-driven autophagic pathway operational in dendritic cells. Autophagy 9, 861–80 (2013).

PubMed
255 Saito, T. et al. p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming. Nat. Commun. 7, (2016).

PubMed
256 Birgisdottir, Å. et al. Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs. Autophagy. , Jan-23 (2019)

PubMed
257 Nicot, A.-S. et al. Phosphorylation of NBR1 by GSK3 modulates protein aggregation. Autophagy 10, 1036–53 (2014).

PubMed
258 Sato, S. et al. Loss of autophagy in dopaminergic neurons causes Lewy pathology and motor dysfunction in aged mice. Sci.Rep. 8, 2813 (2018)

PubMed
259 Koyuncu, S. et al. The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington&quot;s disease patients. Nat.Commun. 9, 2886 (2018).

PubMed
260 Deitersen J et al. High-throughput screening for natural compound-based autophagy modulators reveals novel chemotherapeutic mode of action for arzanol. Cell Death Dis 2021 May;12(6):560
Deitersen J et al
2021/01/01
PubMed
261 Pellegrini, C. et al. Altered adipocyte differentiation and unbalanced autophagy in type 2 Familial Partial Lipodystrophy: an in vitro and in vivo study of adipose tissue browning. Exp.Mol.Med. 51, 89 (2019)

PubMed
262 McLelland, G. et al. Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy. Elife. 7,  (2018).

PubMed
263 Lenoir, O. et al. Endothelial cell and podocyte autophagy synergistically protect from diabetes-induced glomerulosclerosis. Autophagy 11, 1130–45 (2015).

PubMed
264 Lee, M. Y. et al. Peroxisomal protein PEX13 functions in selective autophagy. EMBO Rep. 18, 48–60 (2017).

PubMed
265 Tang, T. et al. Dihydroartemisinin and its anticancer activity against endometrial carcinoma and cervical cancer: involvement of apoptosis, autophagy and transferrin receptor. Singapore.Med.J. , (2019)

PubMed
266 Chakraborty, D. et al. Enhanced autophagic-lysosomal activity and increased BAG3-mediated selective macroautophagy as adaptive response of neuronal cells to chronic oxidative stress. Redox.Biol. 24, 101181 (2019)

PubMed
267 Jakobi, A. et al. Structural basis of p62/SQSTM1 helical filaments and their role in cellular cargo uptake. Nat.Commun. 11, 440 (2020)

PubMed
268 Vincent, A. et al. Subcellular origin of mitochondrial DNA deletions in human skeletal muscle. Ann.Neurol. 84, 289-301 (2018).

PubMed
269 Clayton, E. L. et al. Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology. Acta Neuropathol. 130, 511–23 (2015).

PubMed
270 Salas, E., Roy, S., Marsh, T., Rubin, B. & Debnath, J. Oxidative Pentose Phosphate Pathway Inhibition Is A Key Determinant of Antimalarial Induced Cancer Cell Death. Oncogene 35, 2913–2922 (2016).

PubMed
271 Murrow, L., Malhotra, R. & Debnath, J. ATG12-ATG3 Interacts with Alix to Promote Basal Autophagic Flux and Late Endosome Function. Nat. Cell Biol. 17, 300–310 (2015).

PubMed
272 Matta, S. et al. NADPH Oxidase and Guanylate Binding Protein 5 Restrict Survival of Avirulent Type III Strains of Toxoplasma gondii in Naive Macrophages. MBio. 9,  (2018).

PubMed
273 Viana-Huete, V. et al. Male Brown Fat-Specific Double Knockout of IGFIR/IR: Atrophy, Mitochondrial Fission Failure, Impaired Thermogenesis, and Obesity. Endocrinology. 159, 323-340 (2018)

PubMed
274 Agarwal, S. et al. Autophagy and endosomal trafficking inhibition by Vibrio cholerae MARTX toxin phosphatidylinositol- 3-phosphate-specific phospholipase A1 activity. Nat. Commun. 6, (2015).

PubMed
275 Cottam, E. M., Whelband, M. C. & Wileman, T. Coronavirus NSP6 restricts autophagosome expansion. Autophagy 10, (2014).

PubMed
276 Wang, Y. et al. Autophagy inhibition specifically promotes epithelial-mesenchymal transition and invasion in RAS-mutated cancer cells. Autophagy. , Jan-14 (2019)

PubMed
277 Echeverry, N. et al. Inhibition of autophagy sensitizes malignant pleural mesothelioma cells to dual PI3K/mTOR inhibitors. Cell Death Dis. 6, (2015).

PubMed
278 Fern叩ndez, A. et al. Disruption of the beclin 1-BCL2 autophagy regulatory complex promotes longevity in mice. Nature. 558, 136-140 (2018)

PubMed
279 Klionsky, D. J. et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12, 1 (2016).

PubMed
280 Sebastiani, A. et al. Sequestosome 1 Deficiency Delays, but Does Not Prevent Brain Damage Formation Following Acute Brain Injury in Adult Mice. Front.Neurosci. 11, 678 (2018).

PubMed
281 Park, S. et al. A lysosomal chloride ion-selective fluorescent probe for biological applications. Chem.Sci. 10, 56-66 (2019)

PubMed
282 Gurlo, T. et al. Pregnancy in human IAPP transgenic mice recapitulates beta cell stress in type 2 diabetes. Diabetologia. 62, 1000-1010 (2019)

PubMed
283 Carballo-Carbajal, I. et al. Brain tyrosinase overexpression implicates age-dependent neuromelanin production in Parkinson&quot;s disease pathogenesis. Nat.Commun. 10, 973 (2019)

PubMed
284 Saegusa, C. et al. Low-dose rapamycin-induced autophagy in cochlear outer sulcus cells.. Laryngoscope Investig Otolaryngol. 5, 520-528(2020).

PubMed
285 Ulbricht, A. et al. Induction and adaptation of chaperone-assisted selective autophagy CASA in response to resistance exercise in human skeletal muscle. Autophagy 11, 538–546 (2015).

PubMed
286 Ruozi, G. et al. AAV-mediated in vivo functional selection of tissue-protective factors against ischaemia. Nat. Commun. 6, (2015).

PubMed
287 Starheim, K. et al. Intracellular glutathione determines borte. cytotoxicity in multiple myeloma cells. Blood Cancer J. 6, (2016).

PubMed
288 Livingston, J. et al. Analysis of HSP27 and the Autophagy Marker LC3B+ Puncta Following Preoperative Chemotherapy Identifies High-Risk Osteosarcoma Patients. Mol.Cancer.Ther. 17, 1315-1323 (2018)

PubMed
289 Werner, G. et al. Loss of TMEM106B potentiates lysosomal and FTLD-like pathology in progranulin-deficient mice. EMBO Rep. 21, e50241(2020).

PubMed
290 Zhou, Z. et al. Autophagy supports color vision. Autophagy 11, 1821–1832 (2015).

PubMed
291 Hartupee, J. et al. Impaired Protein Quality Control During Left Ventricular Remodeling in Mice With Cardiac Restricted Overexpression of Tumor Necrosis Factor. Circ.Heart.Fail. 10,  (2017).

PubMed
292 Dunlop, E. A. et al. FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation. Autophagy 10, 1749–1760 (2014).

PubMed
293 Lim, S. W., Jin, L., Jin, J. & Yang, C. W. Effect of Exendin-4 on Autophagy Clearance in Beta Cell of Rats with Tacrolimus-induced Diabetes Mellitus. Nat. Publ. Gr. 6, (2016).

PubMed
294 Giaime, E. et al. Age-Dependent Dopaminergic Neurodegeneration and Impairment of the Autophagy-Lysosomal Pathway in LRRK-Deficient Mice. Neuron. 96, 796-807.e6 (2017)

PubMed
295 Ra, E. A. et al. TRIM31 promotes Atg5/Atg7-independent autophagy in intestinal cells. Nat. Commun. 7, (2016).

PubMed
296 Costes, S., Gurlo, T., Rivera, J. F. & Butler, P. C. UCHL1 deficiency exacerbates human islet amyloid polypeptide toxicity in β-cells: evidence of interplay between the ubiquitin/proteasome system and autophagy. Autophagy 10, 1004–14 (2014).

PubMed
297 Schober, A. et al. Cell Loss and Autophagy in the Extra‐Adrenal Chromaffin Organ of Zuckerkandl are Regulated by Glucocorticoid Signalling. J. Neuroendocrinol. 25, 34–47 (2013)

PubMed
298 Ogmundsd坦ttir, M. et al. A short isoform of ATG7 fails to lipidate LC3/GABARAP. Sci.Rep. 8, 14391 (2018).

PubMed
299 Liu, S. et al. Disrupted autophagy after spinal cord injury is associated with ER stress and neuronal cell death. Cell Death Dis. 6, (2015).

PubMed
300 Igawa, H. et al. p62-mediated autophagy affects nutrition-dependent insulin receptor substrate 1 dynamics in 3T3-L1 preadipocytes. J.Diabetes.Investig. 10, 32-42 (2019)

PubMed
301 Corcelle-Termeau, E. et al. Excess sphingomyelin disturbs ATG9A trafficking and autophagosome closure. Autophagy 12, 533–849 (2016)

PubMed
302 Duleh, S., Wang, X., Komirenko, A. & Margeta, M. Activation of the Keap1/Nrf2 stress response pathway in autophagic vacuolar myopathies. Acta Neuropathol. Commun. 4, 115 (2016).

PubMed
303 Himuro, M. et al. Cellular Autophagy in 留 Cells Plays a Role in the Maintenance of Islet Architecture. J.Endocr.Soc. 3, 1979-1992 (2019)

PubMed
304 Sergin, I. et al. p62-enriched inclusion bodies in macrophages protect against atherosclerosis HHS Public Access. Sci. Signal. 9, (2016).

PubMed
305 Castets, P. et al. mTORC1 and PKB/Akt control the muscle response to denervation by regulating autophagy and HDAC4. Nat.Commun. 10, 3187 (2019)

PubMed
306 Nascimbeni, A. et al. Local detection of PtdIns3P at autophagosome biogenesis membrane platforms. Autophagy. 13, 1602-1612 (2017).

PubMed
307 Carroll, B. et al. Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis. Nat.Commun. 9, 256 (2018).

PubMed
308 Schmitz K et al. An essential role of the autophagy activating kinase ULK1 in snRNP biogenesis. Nucleic Acids Res 2021 06;49(11):6437-6455
Schmitz K et al
2021/01/01
PubMed
309 Spilman, P. et al. Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer’s Disease. PLoS One 5, e9979 (2010).

PubMed
310 Baeken MW et al. Novel Insights into the Cellular Localization and Regulation of the Autophagosomal Proteins LC3A, LC3B and LC3C. Cells 2020 10;9(10)
Baeken MW et al
2020/01/01
PubMed
311 Alam, S. et al. Aberrant Mitochondrial Fission Is Maladaptive in Desmin Mutation-Induced Cardiac Proteotoxicity. J.Am.Heart.Assoc. 7,  (2018).

PubMed
312 Klimek, C. et al. The Hippo network kinase STK38 contributes to protein homeostasis by inhibiting BAG3-mediated autophagy. Biochim. Biophys. Acta - Mol. Cell Res. 1866, 1556–1566 (2019).

PubMed
313 Feldmann, A. et al. The RAB GTPase RAB18 modulates macroautophagy and proteostasis. Biochem. Biophys. Res. Commun. 486, 738–743 (2017).

PubMed
314 Yuan, H.-X., Russell, R. C. & Guan, K.-L. Regulation of PIK3C3/VPS34 complexes by MTOR in nutrient stress-induced autophagy. Autophagy 9, 1983–95 (2013).

PubMed
315 Oehl, K. et al. Live-Cell Mesothelioma Biobank to Explore Mechanisms of Tumor Progression. Front.Oncol. 8, 40 (2018).

PubMed
316 Kakimoto, Y. et al. Myocardial cathepsin D is downregulated in sudden cardiac death. PLoS.One. 15, e0230375 (2020)

PubMed
317 Ma, X. et al. Transcription Factor EB Activation Rescues Advanced 留B-Crystallin Mutation-Induced Cardiomyopathy by Normalizing Desmin Localization. J.Am.Heart.Assoc. 8, e010866 (2019)

PubMed
318 Yanagisawa, H. et al. L-leucine and SPNS1 coordinately ameliorate dysfunction of autophagy in mouse and human Niemann-Pick type C disease. Sci.Rep. 7, 15944 (2017).

PubMed
319 Aishwarya, R. et al. Pleiotropic effects of mdivi-1 in altering mitochondrial dynamics, respiration, and autophagy in cardiomyocytes. Redox Biol. 36, 101660(2020).

PubMed
320 Nozaki, M. et al. SQSTM1L341V variant that is linked to sporadic ALS exhibits impaired association with MAP1LC3 in cultured cells. eNeurologicalSci. 22, 100301(2021).

PubMed
321 Chandrachud, U. et al. Unbiased Cell-based Screening in a Neuronal Cell Model of Batten Disease Highlights an Interaction between Ca 2+ Homeostasis, Autophagy, and CLN3 Protein Function. J. Biol. Chem. 290, 14361–14380 (2015).

PubMed
322 Leidal, A. et al. The LC3-conjugation machinery specifies the loading of RNA-binding proteins into extracellular vesicles. Nat.Cell.Biol. 22, 187-199 (2020)

PubMed
323 Fung, G. et al. Phosphorylation and degradation of 留B-crystallin during enterovirus infection facilitates viral replication and induces viral pathogenesis. Oncotarget. 8, 74767-74780 (2017).

PubMed
324 Bhushan J et al. ISG15 Connects Autophagy and IFN-&#x3B3;-Dependent Control of Toxoplasma gondii Infection in Human Cells. mBio 2020 10;11(5)
Bhushan J et al
2020/01/01
PubMed
325 Kim, W. et al. Atg7-dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokalemia. Sci.Rep. 9, 3021 (2019)

PubMed
326 Mishra, P. et al. Discovery of pan autophagy inhibitors through a high-throughput screen highlights macroautophagy as an evolutionarily conserved process across 3 eukaryotic kingdoms. Autophagy. 13, 1556-1572 (2017).

PubMed
327 Cui, Y. H. et al. Autophagy of the m6A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis. Nat. Commun. 12, 1–19 (2021).

PubMed
328 Kravic, B. et al. In mammalian skeletal muscle, phosphorylation of TOMM22 by protein kinase CSNK2/CK2 controls mitophagy. Autophagy. 14, 311-335 (2017)

PubMed
329 Dubois, C. et al. Co-targeting Mitochondrial Ca2+ Homeostasis and Autophagy Enhances Cancer Cells&quot; Chemosensitivity. iScience. 23, 101263(2020).

PubMed
330 Yang, S. et al. m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade. Nat.Commun. 10, 2782 (2019)

PubMed
331 Choi, I. et al. Microglia clear neuron-released 留-synuclein via selective autophagy and prevent neurodegeneration. Nat.Commun. 11, 1386 (2020)

PubMed
332 Bartolomeo, R. et al. mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy. J.Clin.Invest. 127, 3717-3729 (2017)

PubMed
333 Liang, S. et al. Murine macrophage autophagy protects against alcohol-induced liver injury by degrading interferon regulatory factor 1 (IRF1) and removing damaged mitochondria. J.Biol.Chem. , (2019)

PubMed
334 Kuno, A. et al. Resveratrol Ameliorates Mitophagy Disturbance and Improves Cardiac Pathophysiology of Dystrophin-deficient mdx Mice. Sci.Rep. 8, 15555 (2018).

PubMed
335 Tamura, N. et al. Hyperosmotic stress induces unconventional autophagy independent of the Ulk1 complex. Mol.Cell.Biol. , (2019)

PubMed
336 Wu, Z. et al. Ubiquitination of ABCE1 by NOT4 in Response to Mitochondrial Damage Links Co-translational Quality Control to PINK1-Directed Mitophagy. Cell.Metab. 28, 130-144.e7 (2018)

PubMed
337 Glenn JK et al. Task delegation to physician extenders--some comparisons. Am J Public Health 1976 Jan;66(1):64-6
Glenn JK et al
1976/01/01
PubMed
338 Jacquier, A. et al. Cryptic amyloidogenic elements in mutant NEFH causing Charcot-Marie-Tooth 2 trigger aggresome formation and neuronal death. Acta Neuropathol. Commun. 5, 55 (2017).

PubMed
339 Achour, I. et al. Oleuropein Prevents Neuronal Death, Mitigates Mitochondrial Superoxide Production and Modulates Autophagy in a Dopaminergic Cellular Model. Int. J. Mol. Sci. 17, 1293 (2016)

PubMed
340 Furuya, N. et al. NDP52 interacts with mitochondrial RNA poly(A) polymerase to promote mitophagy. EMBO.Rep. 19, (2018)

PubMed
341 Puvirajesinghe, T. M. et al. Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer. Nat. Commun. 7, (2016).

PubMed
342 Karlsson, A. B. et al. The role of spartin and its novel ubiquitin binding region in DALIS occurrence. Mol. Biol. Cell 25, 1355–1365 (2014).

PubMed
343 Baranowska, K. et al. Hydroxychloroquine potentiates carfilzomib toxicity towards myeloma cells. Oncotarget 7, 70845–70856 (2016)

PubMed
344 Varea, O., Guinovart, J. J. & Duran, J. Malin restoration as proof of concept for gene therapy for Lafora disease. Brain Commun. 4, (2022).

PubMed
345 Aas, A. et al. Nucleocytoplasmic Shuttling of FTO Does Not Affect Starvation-Induced Autophagy. PLoS One 12, e0168182 (2017).

PubMed
346 Pigna, E. et al. Histone deacetylase 4 protects from denervation and skeletal muscle atrophy in a murine model of amyotrophic lateral sclerosis. EBioMedicine. 40, 717-732 (2019)

PubMed
347 Schl端termann D et al. FIP200 controls the TBK1 activation threshold at SQSTM1/p62-positive condensates. Sci Rep 2021 Jul;11(1):13863
Schl端termann D et al
2021/01/01
PubMed
348 Cabe, M. et al. PB1 and UBA domains of p62 are essential for aggresome-like induced structure formation. Biochem.Biophys.Res.Commun. 503, 2306-2311 (2018)

PubMed
349 Takahashi, M. et al. USP10 Is a Driver of Ubiquitinated Protein Aggregation and Aggresome Formation to Inhibit Apoptosis. iScience. 9, 433-450 (2018).

PubMed
350 Garcia, D. et al. Genetic Liver-Specific AMPK Activation Protects against Diet-Induced Obesity and NAFLD. Cell.Rep. 26, 192-208.e6 (2019)

PubMed
351 Zatloukal, B. et al. Sensitivity and specificity of in situ proximity ligation for protein interaction analysis in a model of steatohepatitis with mallory-denk bodies. PLoS One 9, (2014).

PubMed
352 Vanzo, R. et al. Autophagy role(s) in response to oncogenes and DNA replication stress. Cell.Death.Differ. , (2019)

PubMed
353 Joachim, J. et al. Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy. Curr. Biol. 27, 2123–2136.e7 (2017).

PubMed
354 Lachance, V. et al. Autophagy protein NRBF2 has reduced expression in Alzheimer&quot;s brains and modulates memory and amyloid-beta homeostasis in mice. Mol.Neurodegener. 14, 43 (2019)

PubMed
355 Shackelford, D. B. et al. LKB1 inactivation dictates therapeutic response of non-small cell lung cancer to the metabolism drug phenformin. Cancer Cell 23, 143–58 (2013).

PubMed
356 Ruf, S. et al. PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy. Autophagy 13, 486–505 (2017).

PubMed
357 Vargas, T. et al. Selective degradation of PU.1 during autophagy represses the differentiation and antitumour activity of TH9 cells. Nat.Commun. 8, 559 (2017).

PubMed
358 Kondratskyi, A. et al. Identification of ML-9 as a lysosomotropic agent targeting autophagy and cell death. Cell Death Dis. 5, (2014).

PubMed
359 Solvik TA et al. Secretory autophagy maintains proteostasis upon lysosome inhibition. J Cell Biol 2022 Jun;221(6)
Solvik TA et al
2022/01/01
PubMed
360 Kakuta, S. et al. Small GTPase Rab1B is associated with ATG9A vesicles and regulates autophagosome formation. FASEB.J. 31, 3757-3773 (2017)

PubMed
361 Nthiga TM et al. Regulation of Golgi turnover by CALCOCO1-mediated selective autophagy. J Cell Biol 2021 Jun;220(6)
Nthiga TM et al
2021/01/01
PubMed
362 Anisimov, S. et al. G3BP1 inhibits ubiquitinated protein aggregations induced by p62 and USP10. Sci.Rep. 9, 12896 (2019)

PubMed
363 Larroquette, F. et al. Vapb/Amyotrophic lateral sclerosis 8 knock-in mice display slowly progressive motor behavior defects accompanying ER stress and autophagic response. Hum. Mol. Genet. 24, 6515–6529 (2015).

PubMed
364 Gabandé-Rodrıuez, E., Boya, P., Labrador, V., Dotti, C. & Ledesma, M. High sphingomyelin levels induce lysosomal damage and autophagy dysfunction in N324ann Pick disease type A. Cell Death Differ. 21, 864–875 (2014).

PubMed
365 Cui, D. et al. Impaired autophagosome clearance contributes to neuronal death in a piglet model of neonatal hypoxic-ischemic encephalopathy. Cell Death Dis. 8, e2919 (2017)

PubMed
366 Nikam, A. et al. The PPAR留 Agonist Fenofibrate Prevents Formation of Protein Aggregates (Mallory-Denk bodies) in a Murine Model of Steatohepatitis-like Hepatotoxicity. Sci.Rep. 8, 12964 (2018).

PubMed
367 Qiang, L. et al. Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis. Autophagy. 13, 2086-2103 (2017)

PubMed
368 Yanagisawa, H. et al. L-leucine and SPNS1 coordinately ameliorate dysfunction of autophagy in mouse and human N324ann-Pick type C disease. Sci.Rep. 7, 15944 (2017).

PubMed
369 Puvirajesinghe, T. M. et al. Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2窶笛NK signalling in breast cancer. Nat. Commun. 7, (2016).

PubMed
370 Sahani, M. H., Itakura, E. & Mizushima, N. Expression of the autophagy substrate SQSTM1/p62 is restored during prolonged starvation depending on transcriptional upregulation and autophagy-derived amino acids. Autophagy 10, 431–41 (2014).

PubMed
371 Sharma K et al. Autophagy modulates cell fate decisions during lineage commitment. Autophagy 2022 Aug;18(8):1915-1931
Sharma K et al
2022/01/01
PubMed
372 S淡nder SL et al. Restructuring of the plasma membrane upon damage by LC3-associated macropinocytosis. Sci Adv 2021 Jul;7(27)
S淡nder SL et al
2021/01/01
PubMed
373 Pasquier, A. et al. Lysosomal degradation of newly formed insulin granules contributes to 硫 cell failure in diabetes. Nat.Commun. 10, 3312 (2019)

PubMed
374 Morimoto, D. et al. The unexpected role of polyubiquitin chains in the formation of fibrillar aggregates. Nat. Commun. 6, (2015).

PubMed
375 Takahashi, S. et al. Loss of autophagy impairs physiological steatosis by accumulation of NCoR1. Life.Sci.Alliance. 3, (2020)

PubMed
376 Sabino, C. et al. Bafilomycin A1 and U18666A Efficiently Impair ZIKV Infection. Viruses. 11, (2019)

PubMed
377 Oliv辿, M. et al. Myoglobinopathy is an adult-onset autosomal dominant myopathy with characteristic sarcoplasmic inclusions. Nat.Commun. 10, 1396 (2019)

PubMed
378 Kageyama, S. et al. Proteasome Dysfunction Activates Autophagy and the Keap1-Nrf2 Pathway. J. Biol. Chem. 289, 24944–24955 (2014).

PubMed
379 Venkatesh, A., Ma, S. & Punzo, C. TSC but not PTEN loss in starving cones of retinitis pigmentosa mice leads to an autophagy defect and mTORC1 dissociation from the lysosome. Cell Death Dis. 7, e2279窶兎2279 (2016).

PubMed
380 Hoem, G. et al. The FMRpolyGlycine Protein Mediates Aggregate Formation and Toxicity Independent of the CGG mRNA Hairpin in a Cellular Model for FXTAS. Front.Genet. 10, 249 (2019)

PubMed
381 Ziegler, P. et al. Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis. Cell. 174, 88-101.e16 (2018)

PubMed
382 Liu, S. et al. Lysosomal damage after spinal cord injury causes accumulation of RIPK1 and RIPK3 proteins and potentiation of necroptosis. Cell.Death.Dis. 9, 476 (2018).

PubMed
383 Mildenberger, J. et al. N-3 PUFAs induce inflammatory tolerance by formation of KEAP1-containing SQSTM1/p62-bodies and activation of NFE2L2. Autophagy 00–00 (2017).

PubMed
384 Barutcu, S. et al. Role of the MAPK/cJun NH2-terminal kinase signaling pathway in starvation-induced autophagy. Autophagy. 14, 1586-1595 (2018).

PubMed
385 Khan, M. M. et al. Role of autophagy, SQSTM1, SH3GLB1, and TRIM63 in the turnover of nicotinic acetylcholine receptors. Autophagy 10, 123–36 (2014).

PubMed
386 Mercer TJ et al. Phosphoproteomic identification of ULK substrates reveals VPS15-dependent ULK/VPS34 interplay in the regulation of autophagy. EMBO J 2021 Jul;40(14):e105985
Mercer TJ et al
2021/01/01
PubMed
387 Prabakaran, T. et al. Attenuation of cGAS-STING signaling is mediated by a p62/SQSTM1-dependent autophagy pathway activated by TBK1. EMBO.J. 37, (2018)

PubMed
388 Mejlvang, J. et al. Starvation induces rapid degradation of selective autophagy receptors by endosomal microautophagy. J.Cell.Biol. 217, 3640-3655 (2018)

PubMed
389 Goodwin, J.M. et al. GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis. Sci Adv. 7, eabj2485(2021).

PubMed
390 Tanaka, K. et al. A Novel Acylaminoimidazole Derivative, WN1316, Alleviates Disease Progression via Suppression of Glial Inflammation in ALS Mouse Model. PLoS One 9, (2014).

PubMed
391 Mitsui, S. et al. Systemic overexpression of SQSTM1/p62 accelerates disease onset in a SOD1H46R-expressing ALS mouse model. Mol.Brain. 11, 30 (2018).

PubMed
392 Todoric, J. et al. Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas. Cancer.Cell. 32, 824-839.e8 (2017)

PubMed
393 Waguri, S. & Komatsu, M. Chapter 9 Biochemical and Morphological Detection of Inclusion Bodies in Autophagy-Deficient Mice. Methods in Enzymology 453, 181–196 (2009).

PubMed
394 Sarraf, S. et al. PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis. Cell.Rep. 29, 225-235.e5 (2019)

PubMed
395 Zhang, J. et al. A Founder Mutation in VPS11 Causes an Autosomal Recessive Leukoencephalopathy Linked to Autophagic Defects. PLoS Genet. 12,(2016).

PubMed
396 Fajardo, V. A. et al. Sarcolipin deletion exacerbates soleus muscle atrophy and weakness in phospholamban overexpressing mice. PLoS One 12, e0173708 (2017).

PubMed
397 Taneike, M. et al. mTOR Hyperactivation by Ablation of Tuberous Sclerosis Complex 2 in the Mouse Heart Induces Cardiac Dysfunction with the Increased Number of Small Mitochondria Mediated through the Down-Regulation of Autophagy. PLoS One 11, (2016).

PubMed
398 Dohmen, M. et al. AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy. Nat.Commun. 11, 1032 (2020)

PubMed
399 Bl叩zquez C et al. Inhibition of striatonigral autophagy as a link between cannabinoid intoxication and impairment of motor coordination. Elife 2020 Aug;9
Bl叩zquez C et al
2020/01/01
PubMed
400 Aghajan, M. et al. Antisense oligonucleotide treatment ameliorates IFN-粒-induced proteinuria in APOL1-transgenic mice. JCI.Insight. 4, (2019)

PubMed
401 Ricketts, T. et al. A nonsense mutation in mouse Tardbp affects TDP43 alternative splicing activity and causes limb-clasping and body tone defects. PLoS One 9, (2014).

PubMed
402 Felzen, V. et al. Estrogen receptor 留 regulates non-canonical autophagy that provides stress resistance to neuroblastoma and breast cancer cells and involves BAG3 function. Cell Death Dis. 6, (2015).

PubMed
403 Lim, H. et al. A novel autophagy enhancer as a therapeutic agent against metabolic syndrome and diabetes. Nat.Commun. 9, 1438 (2018).

PubMed
404 Li, Y. et al. cPLA2 activation contributes to lysosomal defects leading to impairment of autophagy after spinal cord injury. Cell.Death.Dis. 10, 531 (2019)

PubMed
405 Jarvela, T. S. et al. The neural chaperone proSAAS blocks 留-synuclein fibrillation and neurotoxicity. Proc. Natl. Acad. Sci. U. S. A. (2016).

PubMed
406 Kenific, C. M. et al. NBR1 enables autophagy-dependent focal adhesion turnover. J. Cell Biol. 212, 577–90 (2016).

PubMed
407 Yamada, T. et al. Mitochondrial Stasis Reveals p62-Mediated Ubiquitination in Parkin-Independent Mitophagy and Mitigates Nonalcoholic Fatty Liver Disease. Cell.Metab. , (2018)

PubMed
408 McMillan, E. M. et al. Autophagic signaling and proteolytic enzyme activity in cardiac and skeletal muscle of spontaneously hypertensive rats following chronic aerobic exercise. PLoS One 10, e0119382 (2015).

PubMed
409 Rudnick JA et al. Autophagy in stromal fibroblasts promotes tumor desmoplasia and mammary tumorigenesis. Genes Dev 2021 Jul;35(13-14):963-975
Rudnick JA et al
2021/01/01
PubMed
410 Suzuki, C. et al. Autophagy Deficiency in Renal Proximal Tubular Cells Leads to an Increase in Cellular Injury and Apoptosis under Normal Fed Conditions. Int.J.Mol.Sci. 21, (2019)

PubMed
411 Zhang, L. et al. HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress. Nat. Commun. 5, (2014).

PubMed
412 Kawakami, I. et al. Progression of phosphorylated 留-synuclein in Macaca fuscata. Brain Pathol. 31, e12952(2021).

PubMed
  • No.: 1
  • 文献情報:
    Puvirajesinghe TM et al. Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer. Nat Commun 2016;7:10318
    Puvirajesinghe TM et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 2
  • 文献情報:
    Shi J et al. NBR1 is dispensable for PARK2-mediated mitophagy regardless of the presence or absence of SQSTM1. Cell Death Dis 2015;6:e1943
    Shi J et al
    2015/01/01
  • 備考:
    Application: WB
  • 参照:
    PubMed
  • No.: 3
  • 文献情報:
    Agarwal S et al. Autophagy and endosomal trafficking inhibition by Vibrio cholerae MARTX toxin phosphatidylinositol-3-phosphate-specific phospholipase A1 activity. Nat Commun 2015;6:8745
    Agarwal S et al
    2015/01/01
  • 備考:
    Application: WB
  • 参照:
    PubMed
  • No.: 4
  • 文献情報:
    Eino A et al. Sqstm1-GFP knock-in mice reveal dynamic actions of Sqstm1 during autophagy and under stress conditions in living cells. J. Cell. Sci. 2015 Dec;128(23):4453-61
    Eino A et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 5
  • 文献情報:
    Pellegrini C et al. All-trans retinoic acid and rapamycin normalize Hutchinson Gilford progeria fibroblast phenotype. Oncotarget 2015 Oct;6(30):29914-28
    Pellegrini C et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 6
  • 文献情報:
    Clayton EL et al. Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology. Acta Neuropathol. 2015 Oct;130(4):511-23
    Clayton EL et al
    2015/01/01
  • 備考:
    Application: IF
  • 参照:
    PubMed
  • No.: 7
  • 文献情報:
    Newton PT et al. Pharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner. Autophagy 2015;11(9):1594-607
    Newton PT et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 8
  • 文献情報:
    Felzen V et al. Estrogen receptor &#x3B1; regulates non-canonical autophagy that provides stress resistance to neuroblastoma and breast cancer cells and involves BAG3 function. Cell Death Dis 2015;6:e1812
    Felzen V et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 9
  • 文献情報:
    Ruozi G et al. AAV-mediated in vivo functional selection of tissue-protective factors against ischaemia. Nat Commun 2015;6:7388
    Ruozi G et al
    2015/01/01
  • 備考:
    Application: WB
  • 参照:
    PubMed
  • No.: 10
  • 文献情報:
    Milan E et al. A plastic SQSTM1/p62-dependent autophagic reserve maintains proteostasis and determines proteasome inhibitor susceptibility in multiple myeloma cells. Autophagy 2015;11(7):1161-78
    Milan E et al
    2015/01/01
  • 備考:
    Application: WB, IF
  • 参照:
    PubMed
  • No.: 11
  • 文献情報:
    Echeverry N et al. Inhibition of autophagy sensitizes malignant pleural mesothelioma cells to dual PI3K/mTOR inhibitors. Cell Death Dis 2015;6:e1757
    Echeverry N et al
    2015/01/01
  • 備考:
    Application: WB
  • 参照:
    PubMed
  • No.: 12
  • 文献情報:
    Akizu N et al. Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction. Nat. Genet. 2015 May;47(5):528-34
    Akizu N et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 13
  • 文献情報:
    McMillan EM et al. Autophagic signaling and proteolytic enzyme activity in cardiac and skeletal muscle of spontaneously hypertensive rats following chronic aerobic exercise. PLoS ONE 2015;10(3):e0119382
    McMillan EM et al
    2015/01/01
  • 備考:
    Application: WB
  • 参照:
    PubMed
  • No.: 14
  • 文献情報:
    Murrow L et al. ATG12-ATG3 interacts with Alix to promote basal autophagic flux and late endosome function. Nat. Cell Biol. 2015 Mar;17(3):300-10
    Murrow L et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 15
  • 文献情報:
    Lim J et al. Proteotoxic stress induces phosphorylation of p62/SQSTM1 by ULK1 to regulate selective autophagic clearance of protein aggregates. PLoS Genet. 2015;11(2):e1004987
    Lim J et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 16
  • 文献情報:
    Morimoto D et al. The unexpected role of polyubiquitin chains in the formation of fibrillar aggregates. Nat Commun 2015;6:6116
    Morimoto D et al
    2015/01/01
  • 備考:
    Application: WB, ICC
  • 参照:
    PubMed
  • No.: 17
  • 文献情報:
    Arel-Dubeau AM et al. Cucurbitacin E has neuroprotective properties and autophagic modulating activities on dopaminergic neurons. Oxid Med Cell Longev 2014;2014:425496
    Arel-Dubeau AM et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 18
  • 文献情報:
    Liu S et al. Disrupted autophagy after spinal cord injury is associated with ER stress and neuronal cell death. Cell Death Dis 2015;6:e1582
    Liu S et al
    2015/01/01
  • 備考:
    Application: WB, IHC
  • 参照:
    PubMed
  • No.: 19
  • 文献情報:
    Sarkar C et al. Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury. Autophagy 2014;10(12):2208-22
    Sarkar C et al
    2014/01/01
  • 備考:
    Application: IHC
  • 参照:
    PubMed
  • No.: 20
  • 文献情報:
    Xu X et al. Autophagy is essential for effector CD8(+) T cell survival and memory formation. Nat. Immunol. 2014 Dec;15(12):1152-61
    Xu X et al
    2014/01/01
  • 備考:
    Application: WB
  • 参照:
    PubMed
  • No.: 21
  • 文献情報:
    Dunlop EA et al. FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation. Autophagy 2014 Oct;10(10):1749-60
    Dunlop EA et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 22
  • 文献情報:
    Lim YM et al. Systemic autophagy insufficiency compromises adaptation to metabolic stress and facilitates progression from obesity to diabetes. Nat Commun 2014;5:4934
    Lim YM et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 23
  • 文献情報:
    Kageyama S et al. Proteasome dysfunction activates autophagy and the Keap1-Nrf2 pathway. J. Biol. Chem. 2014 Sep;289(36):24944-55
    Kageyama S et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 24
  • 文献情報:
    Hernandez ED et al. A macrophage NBR1-MEKK3 complex triggers JNK-mediated adipose tissue inflammation in obesity. Cell Metab. 2014 Sep;20(3):499-511
    Hernandez ED et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 25
  • 文献情報:
    Rivera JF et al. Autophagy defends pancreatic &#x3B2; cells from human islet amyloid polypeptide-induced toxicity. J. Clin. Invest. 2014 Aug;124(8):3489-500
    Rivera JF et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 26
  • 文献情報:
    Cottam EM et al. Coronavirus NSP6 restricts autophagosome expansion. Autophagy 2014 Aug;10(8):1426-41
    Cottam EM et al
    2014/01/01
  • 備考:
    Application: WB
  • 参照:
    PubMed
  • No.: 27
  • 文献情報:
    Gaband辿-Rodr鱈guez E et al. High sphingomyelin levels induce lysosomal damage and autophagy dysfunction in Niemann Pick disease type A. Cell Death Differ. 2014 Jun;21(6):864-75
    Gaband辿-Rodr鱈guez E et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 28
  • 文献情報:
    Nicot AS et al. Phosphorylation of NBR1 by GSK3 modulates protein aggregation. Autophagy 2014 Jun;10(6):1036-53
    Nicot AS et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 29
  • 文献情報:
    Heijnen HF et al. Ribosomal protein mutations induce autophagy through S6 kinase inhibition of the insulin pathway. PLoS Genet. 2014;10(5):e1004371
    Heijnen HF et al
    2014/01/01
  • 備考:
    Application: WB
  • 参照:
    PubMed
  • No.: 30
  • 文献情報:
    Kinsey C et al. Plac8 links oncogenic mutations to regulation of autophagy and is critical to pancreatic cancer progression. Cell Rep 2014 May;7(4):1143-55
    Kinsey C et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 31
  • 文献情報:
    Guan BJ et al. Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2&#x3B1;. J. Biol. Chem. 2014 May;289(18):12593-611
    Guan BJ et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 32
  • 文献情報:
    Kondratskyi A et al. Identification of ML-9 as a lysosomotropic agent targeting autophagy and cell death. Cell Death Dis 2014;5:e1193
    Kondratskyi A et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 33
  • 文献情報:
    Ost M et al. Activation of AMPK&#x3B1;2 is not crucial for mitochondrial uncoupling-induced metabolic effects but required to maintain skeletal muscle integrity. PLoS ONE 2014;9(4):e94689
    Ost M et al
    2014/01/01
  • 備考:
    Application: WB
  • 参照:
    PubMed
  • No.: 34
  • 文献情報:
    Karlsson AB et al. The role of spartin and its novel ubiquitin binding region in DALIS occurrence. Mol. Biol. Cell 2014 Apr;25(8):1355-65
    Karlsson AB et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 35
  • 文献情報:
    Furuya N et al. PARK2/Parkin-mediated mitochondrial clearance contributes to proteasome activation during slow-twitch muscle atrophy via NFE2L1 nuclear translocation. Autophagy 2014 Apr;10(4):631-41
    Furuya N et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 36
  • 文献情報:
    Zhang L et al. HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress. Nat Commun 2014;5:3430
    Zhang L et al
    2014/01/01
  • 備考:
    Application: WB, IHC
  • 参照:
    PubMed
  • No.: 37
  • 文献情報:
    Sahani MH et al. Expression of the autophagy substrate SQSTM1/p62 is restored during prolonged starvation depending on transcriptional upregulation and autophagy-derived amino acids. Autophagy 2014 Mar;10(3):431-41
    Sahani MH et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 38
  • 文献情報:
    Yamanaka T et al. NF-Y inactivation causes atypical neurodegeneration characterized by ubiquitin and p62 accumulation and endoplasmic reticulum disorganization. Nat Commun 2014;5:3354
    Yamanaka T et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 39
  • 文献情報:
    Tanaka K et al. A novel acylaminoimidazole derivative, WN1316, alleviates disease progression via suppression of glial inflammation in ALS mouse model. PLoS ONE 2014;9(1):e87728
    Tanaka K et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 40
  • 文献情報:
    Ricketts T et al. A nonsense mutation in mouse Tardbp affects TDP43 alternative splicing activity and causes limb-clasping and body tone defects. PLoS ONE 2014;9(1):e85962
    Ricketts T et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 41
  • 文献情報:
    Khan MM et al. Role of autophagy, SQSTM1, SH3GLB1, and TRIM63 in the turnover of nicotinic acetylcholine receptors. Autophagy 2014 Jan;10(1):123-36
    Khan MM et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 42
  • 文献情報:
    Yuan HX et al. Regulation of PIK3C3/VPS34 complexes by MTOR in nutrient stress-induced autophagy. Autophagy 2013 Dec;9(12):1983-95
    Yuan HX et al
    2013/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 43
  • 文献情報:
    Adolph TE et al. Paneth cells as a site of origin for intestinal inflammation. Nature 2013 Nov;503(7475):272-6
    Adolph TE et al
    2013/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 44
  • 文献情報:
    Ichimura Y et al. Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy. Mol. Cell 2013 Sep;51(5):618-31
    Ichimura Y et al
    2013/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 45
  • 文献情報:
    Kondylis V et al. Endosome-mediated autophagy: an unconventional MIIC-driven autophagic pathway operational in dendritic cells. Autophagy 2013 Jun;9(6):861-80
    Kondylis V et al
    2013/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 46
  • 文献情報:
    Ozcelik S et al. Rapamycin attenuates the progression of tau pathology in P301S tau transgenic mice. PLoS ONE 2013;8(5):e62459
    Ozcelik S et al
    2013/01/01
  • 備考:
    Application: WB
  • 参照:
    PubMed
  • No.: 47
  • 文献情報:
    Raina K et al. Energy deprivation by silibinin in colorectal cancer cells: a double-edged sword targeting both apoptotic and autophagic machineries. Autophagy 2013 May;9(5):697-713
    Raina K et al
    2013/01/01
  • 備考:
    Application: IHC
  • 参照:
    PubMed
  • No.: 48
  • 文献情報:
    Bechtel W et al. Vps34 deficiency reveals the importance of endocytosis for podocyte homeostasis. J. Am. Soc. Nephrol. 2013 Apr;24(5):727-43
    Bechtel W et al
    2013/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 49
  • 文献情報:
    Warr MR et al. FOXO3A directs a protective autophagy program in haematopoietic stem cells. Nature 2013 Feb;494(7437):323-7
    Warr MR et al
    2013/01/01
  • 備考:
    Application: FC/FACS
  • 参照:
    PubMed
  • No.: 50
  • 文献情報:
    Shackelford DB et al. LKB1 inactivation dictates therapeutic response of non-small cell lung cancer to the metabolism drug phenformin. Cancer Cell 2013 Feb;23(2):143-58
    Shackelford DB et al
    2013/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 51
  • 文献情報:
    Jiang S et al. Heavy metal scavenger metallothionein mitigates deep hypothermia-induced myocardial contractile anomalies: role of autophagy. Am. J. Physiol. Endocrinol. Metab. 2013 Jan;304(1):E74-86
    Jiang S et al
    2013/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 52
  • 文献情報:
    Schober A et al. Cell loss and autophagy in the extra-adrenal chromaffin organ of Zuckerkandl are regulated by glucocorticoid signalling. J. Neuroendocrinol. 2013 Jan;25(1):34-47
    Schober A et al
    2013/01/01
  • 備考:
    Application: IHC
  • 参照:
    PubMed
  • No.: 53
  • 文献情報:
    Shiba-Fukushima K et al. PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy. Sci Rep 2012;2:1002
    Shiba-Fukushima K et al
    2012/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 54
  • 文献情報:
    Chakrabarti A et al. RNase L Triggers Autophagy in Response to Viral Infections. J. Virol. 2012 Oct;86(20):11311-21
    Chakrabarti A et al
    2012/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 55
  • 文献情報:
    Nascimbeni AC et al. The role of autophagy in the pathogenesis of glycogen storage disease type II (GSDII). Cell Death Differ. 2012 Oct;19(10):1698-708
    Nascimbeni AC et al
    2012/01/01
  • 備考:
    Application: WB
  • 参照:
    PubMed
  • No.: 56
  • 文献情報:
    Stingele S et al. Global analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells. Mol. Syst. Biol. 2012;8:608
    Stingele S et al
    2012/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 57
  • 文献情報:
    Chong A et al. Cytosolic clearance of replication-deficient mutants reveals Francisella tularensis interactions with the autophagic pathway. Autophagy 2012 Sep;8(9):1342-56
    Chong A et al
    2012/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 58
  • 文献情報:
    Taguchi K et al. Keap1 degradation by autophagy for the maintenance of redox homeostasis. Proc. Natl. Acad. Sci. U.S.A. 2012 Aug;109(34):13561-6
    Taguchi K et al
    2012/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 59
  • 文献情報:
    Fang J et al. Cytotoxic effects of bortezomib in myelodysplastic syndrome/acute myeloid leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and repression of PSMA1. Blood 2012 Jul;120(4):858-67
    Fang J et al
    2012/01/01
  • 備考:
    Species: Human, Application: WB
  • 参照:
    PubMed
  • No.: 60
  • 文献情報:
    Uchida A et al. Non-human primate model of amyotrophic lateral sclerosis with cytoplasmic mislocalization of TDP-43. Brain 2012 Mar;135(Pt 3):833-46
    Uchida A et al
    2012/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 61
  • 文献情報:
    Ghazi-Noori S et al. Progressive neuronal inclusion formation and axonal degeneration in CHMP2B mutant transgenic mice. Brain 2012 Mar;135(Pt 3):819-32
    Ghazi-Noori S et al
    2012/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 62
  • 文献情報:
    Velikkakath AK et al. Mammalian Atg2 proteins are essential for autophagosome formation and important for regulation of size and distribution of lipid droplets. Mol. Biol. Cell 2012 Mar;23(5):896-909
    Velikkakath AK et al
    2012/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 63
  • 文献情報:
    Cottam EM et al. Coronavirus nsp6 proteins generate autophagosomes from the endoplasmic reticulum via an omegasome intermediate. Autophagy 2011 Nov;7(11):1335-47
    Cottam EM et al
    2011/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 64
  • 文献情報:
    Pattison JS et al. Atg7 induces basal autophagy and rescues autophagic deficiency in CryABR120G cardiomyocytes. Circ. Res. 2011 Jul;109(2):151-60
    Pattison JS et al
    2011/01/01
  • 備考:
    Application: WB
  • 参照:
    PubMed
  • No.: 65
  • 文献情報:
    Rivera JF et al. Human-IAPP disrupts the autophagy/lysosomal pathway in pancreatic &#x3B2;-cells: protective role of p62-positive cytoplasmic inclusions. Cell Death Differ. 2011 Mar;18(3):415-26
    Rivera JF et al
    2011/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 66
  • 文献情報:
    Itakura E et al. p62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding. J. Cell Biol. 2011 Jan;192(1):17-27
    Itakura E et al
    2011/01/01
  • 備考:
    Application: ICC
  • 参照:
    PubMed
  • No.: 67
  • 文献情報:
    Narendra D et al. p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both. Autophagy 2010 Nov;6(8):1090-106
    Narendra D et al
    2010/01/01
  • 備考:
    Application: ICC
  • 参照:
    PubMed
  • No.: 68
  • 文献情報:
    Aishima S et al. p62+ Hyaline inclusions in intrahepatic cholangiocarcinoma associated with viral hepatitis or alcoholic liver disease. Am. J. Clin. Pathol. 2010 Sep;134(3):457-65
    Aishima S et al
    2010/01/01
  • 備考:
    Application: IHC
  • 参照:
    PubMed
  • No.: 69
  • 文献情報:
    Itakura E et al. Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins. Autophagy 2010 Aug;6(6):764-76
    Itakura E et al
    2010/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 70
  • 文献情報:
    Spilman P et al. Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer&quot;s disease. PLoS ONE 2010;5(4):e9979
    Spilman P et al
    2010/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 71
  • 文献情報:
    Hartleben B et al. Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice. J. Clin. Invest. 2010 Apr;120(4):1084-96
    Hartleben B et al
    2010/01/01
  • 備考:
    Application: WB
  • 参照:
    PubMed
  • No.: 72
  • 文献情報:
    Lee IH et al. Regulation of autophagy by the p300 acetyltransferase. J. Biol. Chem. 2009 Mar;284(10):6322-8
    Lee IH et al
    2009/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 73
  • 文献情報:
    Bj淡rk淡y G et al. Monitoring autophagic degradation of p62/SQSTM1. Meth. Enzymol. 2009;452:181-97
    Bj淡rk淡y G et al
    2009/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 74
  • 文献情報:
    Kuusisto E et al. Use of p62/SQSTM1 antibodies for neuropathological diagnosis. Neuropathol. Appl. Neurobiol. 2008 Apr;34(2):169-80
    Kuusisto E et al
    2008/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 75
  • 文献情報:
    Janig E et al. Interaction of stress proteins with misfolded keratins. Eur. J. Cell Biol. 2005 Mar;84(2-3):329-39
    Janig E et al
    2005/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 76
  • 文献情報:
    M端ller T et al. Immunohistochemical analysis of Mallory bodies in Wilsonian and non-Wilsonian hepatic copper toxicosis. Hepatology 2004 Apr;39(4):963-9
    M端ller T et al
    2004/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 77
  • 文献情報:
    Furukawa Y et al. Ubiquitin and ubiquitin-related proteins in neurons and dendrites of brains of atypical Pick&quot;s disease without Pick bodies. Neuropathology 2004 Mar;24(1):38-45
    Furukawa Y et al
    2004/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 78
  • 文献情報:
    Arai T et al. Neuronal and glial inclusions in frontotemporal dementia with or without motor neuron disease are immunopositive for p62. Neurosci. Lett. 2003 May;342(1-2):41-4
    Arai T et al
    2003/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 79
  • 文献情報:
    Kuusisto E et al. Early accumulation of p62 in neurofibrillary tangles in Alzheimer&quot;s disease: possible role in tangle formation. Neuropathol. Appl. Neurobiol. 2002 Jun;28(3):228-37
    Kuusisto E et al
    2002/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 80
  • 文献情報:
    Stumptner C et al. Mallory body--a disease-associated type of sequestosome. Hepatology 2002 May;35(5):1053-62
    Stumptner C et al
    2002/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 81
  • 文献情報:
    Zatloukal K et al. p62 Is a common component of cytoplasmic inclusions in protein aggregation diseases. Am. J. Pathol. 2002 Jan;160(1):255-63
    Zatloukal K et al
    2002/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 82
  • 文献情報:
    Stumptner C et al. Analysis of intracytoplasmic hyaline bodies in a hepatocellular carcinoma. Demonstration of p62 as major constituent. Am. J. Pathol. 1999 Jun;154(6):1701-10
    Stumptner C et al
    1999/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 83
  • 文献情報:
    Santanam U et al. Atg7 cooperates with Pten loss to drive prostate cancer tumor growth. Genes Dev. 2016 Feb;30(4):399-407
    Santanam U et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 84
  • 文献情報:
    Sergin I et al. Inclusion bodies enriched for p62 and polyubiquitinated proteins in macrophages protect against atherosclerosis. Sci Signal 2016 Jan;9(409):ra2
    Sergin I et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 85
  • 文献情報:
    Starheim KK et al. Intracellular glutathione determines bortezomib cytotoxicity in multiple myeloma cells. Blood Cancer J 2016 Jul;6(7):e446
    Starheim KK et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 86
  • 文献情報:
    Yamanaka T et al. Differential roles of NF-Y transcription factor in ER chaperone expression and neuronal maintenance in the CNS. Sci Rep 2016 Sep;6:34575
    Yamanaka T et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 87
  • 文献情報:
    Lim SW et al. Effect of Exendin-4 on Autophagy Clearance in Beta Cell of Rats with Tacrolimus-induced Diabetes Mellitus. Sci Rep 2016 Jul;6:29921
    Lim SW et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 88
  • 文献情報:
    Angelini C et al. Lipolysis and lipophagy in lipid storage myopathies. Biochim. Biophys. Acta 2016 Jul;1862(7):1367-73
    Angelini C et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 89
  • 文献情報:
    Corcelle-Termeau E et al. Excess sphingomyelin disturbs ATG9A trafficking and autophagosome closure. Autophagy 2016 May;12(5):833-49
    Corcelle-Termeau E et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 90
  • 文献情報:
    Ra EA et al. TRIM31 promotes Atg5/Atg7-independent autophagy in intestinal cells. Nat Commun 2016 May;7:11726
    Ra EA et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 91
  • 文献情報:
    Kaizuka T et al. Atg13 Is Essential for Autophagy and Cardiac Development in Mice. Mol. Cell. Biol. 2015 Dec;36(4):585-95
    Kaizuka T et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 92
  • 文献情報:
    Saito T et al. p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming. Nat Commun 2016 Jun;7:12030
    Saito T et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 93
  • 文献情報:
    Jarvela TS et al. The neural chaperone proSAAS blocks &#x3B1;-synuclein fibrillation and neurotoxicity. Proc. Natl. Acad. Sci. U.S.A. 2016 08;113(32):E4708-15
    Jarvela TS et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 94
  • 文献情報:
    Weder N et al. Child abuse, depression, and methylation in genes involved with stress, neural plasticity, and brain circuitry. J Am Acad Child Adolesc Psychiatry 2014 Apr;53(4):417-24.e5
    Weder N et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 95
  • 文献情報:
    Klionsky DJ et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 2016;12(1):1-222
    Klionsky DJ et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 96
  • 文献情報:
    Zhang J et al. A Founder Mutation in VPS11 Causes an Autosomal Recessive Leukoencephalopathy Linked to Autophagic Defects. PLoS Genet. 2016 Apr;12(4):e1005848
    Zhang J et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 97
  • 文献情報:
    Kenific CM et al. NBR1 enables autophagy-dependent focal adhesion turnover. J. Cell Biol. 2016 Feb;212(5):577-90
    Kenific CM et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 98
  • 文献情報:
    Taneike M et al. mTOR Hyperactivation by Ablation of Tuberous Sclerosis Complex 2 in the Mouse Heart Induces Cardiac Dysfunction with the Increased Number of Small Mitochondria Mediated through the Down-Regulation of Autophagy. PLoS ONE 2016;11(3):e015262
    Taneike M et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 99
  • 文献情報:
    Lenoir O et al. Endothelial cell and podocyte autophagy synergistically protect from diabetes-induced glomerulosclerosis. Autophagy 2015;11(7):1130-45
    Lenoir O et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 100
  • 文献情報:
    Larroquette F et al. Vapb/Amyotrophic lateral sclerosis 8 knock-in mice display slowly progressive motor behavior defects accompanying ER stress and autophagic response. Hum. Mol. Genet. 2015 Nov;24(22):6515-29
    Larroquette F et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 101
  • 文献情報:
    Hieke N et al. Expression of a ULK1/2 binding-deficient ATG13 variant can partially restore autophagic activity in ATG13-deficient cells. Autophagy 2015;11(9):1471-83
    Hieke N et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 102
  • 文献情報:
    Zhou Z et al. Autophagy supports color vision. Autophagy 2015;11(10):1821-32
    Zhou Z et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 103
  • 文献情報:
    Ciuffa R et al. The selective autophagy receptor p62 forms a flexible filamentous helical scaffold. Cell Rep 2015 May;11(5):748-58
    Ciuffa R et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 104
  • 文献情報:
    Ulbricht A et al. Induction and adaptation of chaperone-assisted selective autophagy CASA in response to resistance exercise in human skeletal muscle. Autophagy 2015 Mar;11(3):538-546
    Ulbricht A et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 105
  • 文献情報:
    Chandrachud U et al. Unbiased Cell-based Screening in a Neuronal Cell Model of Batten Disease Highlights an Interaction between Ca2+ Homeostasis, Autophagy, and CLN3 Protein Function. J. Biol. Chem. 2015 Jun;290(23):14361-80
    Chandrachud U et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 106
  • 文献情報:
    Johansson I et al. The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells. Autophagy 2015;11(9):1636-51
    Johansson I et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 107
  • 文献情報:
    Lodder J et al. Macrophage autophagy protects against liver fibrosis in mice. Autophagy 2015;11(8):1280-92
    Lodder J et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 108
  • 文献情報:
    Costes S et al. UCHL1 deficiency exacerbates human islet amyloid polypeptide toxicity in &#x3B2;-cells: evidence of interplay between the ubiquitin/proteasome system and autophagy. Autophagy 2014 Jun;10(6):1004-14
    Costes S et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 109
  • 文献情報:
    Zatloukal B et al. Sensitivity and specificity of in situ proximity ligation for protein interaction analysis in a model of steatohepatitis with Mallory-Denk bodies. PLoS ONE 2014;9(5):e96690
    Zatloukal B et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 110
  • 文献情報:
    Yamano K et al. PINK1 is degraded through the N-end rule pathway. Autophagy 2013 Nov;9(11):1758-69
    Yamano K et al
    2013/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 111
  • 文献情報:
    Hoshino A et al. Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart. Nat Commun 2013 Aug;4:2308
    Hoshino A et al
    2013/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 112
  • 文献情報:
    Liu S et al. Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury. Autophagy 2012 May;8(5):826-37
    Liu S et al
    2012/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 113
  • 文献情報:
    Germain M et al. MCL-1 is a stress sensor that regulates autophagy in a developmentally regulated manner. EMBO J. 2011 Jan;30(2):395-407
    Germain M et al
    2011/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 114
  • 文献情報:
    Saiki S et al. Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition. Autophagy 2011 Feb;7(2):176-87
    Saiki S et al
    2011/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 115
  • 文献情報:
    Taneike M et al. Inhibition of autophagy in the heart induces age-related cardiomyopathy. Autophagy 2010 Jul;6(5):600-6
    Taneike M et al
    2010/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 116
  • 文献情報:
    Masiero E et al. Autophagy is required to maintain muscle mass. Cell Metab. 2009 Dec;10(6):507-15
    Masiero E et al
    2009/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 117
  • 文献情報:
    Mizushima N et al. How to interpret LC3 immunoblotting. Autophagy ;3(6):542-5
    Mizushima N et al
  • 備考:
  • 参照:
    PubMed
  • No.: 118
  • 文献情報:
    Mildenberger J et al. N-3 PUFAs induce inflammatory tolerance by formation of KEAP1-containing SQSTM1/p62-bodies and activation of NFE2L2. Autophagy 2017 Oct;13(10):1664-1678
    Mildenberger J et al
    2017/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 119
  • 文献情報:
    Jacquier A et al. Cryptic amyloidogenic elements in mutant NEFH causing Charcot-Marie-Tooth 2 trigger aggresome formation and neuronal death. Acta Neuropathol Commun 2017 Jul;5(1):55
    Jacquier A et al
    2017/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 120
  • 文献情報:
    Joachim J et al. Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy. Curr. Biol. 2017 Jul;27(14):2123-2136.e7
    Joachim J et al
    2017/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 121
  • 文献情報:
    Sergin I et al. Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis. Nat Commun 2017 Jun;8:15750
    Sergin I et al
    2017/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 122
  • 文献情報:
    Lee MY et al. Peroxisomal protein PEX13 functions in selective autophagy. EMBO Rep. 2017 Jan;18(1):48-60
    Lee MY et al
    2017/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 123
  • 文献情報:
    Nascimbeni AC et al. Autophagy dysregulation in Danon disease. Cell Death Dis 2017 Jan;8(1):e2565
    Nascimbeni AC et al
    2017/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 124
  • 文献情報:
    Ruf S et al. PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy. Autophagy 2017 Mar;13(3):486-505
    Ruf S et al
    2017/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 125
  • 文献情報:
    Aas A et al. Nucleocytoplasmic Shuttling of FTO Does Not Affect Starvation-Induced Autophagy. PLoS ONE 2017;12(3):e0168182
    Aas A et al
    2017/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 126
  • 文献情報:
    Fajardo VA et al. Sarcolipin deletion exacerbates soleus muscle atrophy and weakness in phospholamban overexpressing mice. PLoS ONE 2017;12(3):e0173708
    Fajardo VA et al
    2017/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 127
  • 文献情報:
    Feldmann A et al. The RAB GTPase RAB18 modulates macroautophagy and proteostasis. Biochem. Biophys. Res. Commun. 2017 05;486(3):738-743
    Feldmann A et al
    2017/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 128
  • 文献情報:
    Duleh S et al. Activation of the Keap1/Nrf2 stress response pathway in autophagic vacuolar myopathies. Acta Neuropathol Commun 2016 Oct;4(1):115
    Duleh S et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 129
  • 文献情報:
    Feldmann, A. et al. The RAB GTPase RAB18 modulates macroautophagy and proteostasis. Biochem. Biophys. Res. Commun. 486, 738-743 (2017).

  • 備考:
    species: human, application: WB, IHC (frozen)
  • 参照:
    PubMed
  • No.: 130
  • 文献情報:
    Fajardo, V. A. et al. Sarcolipin deletion exacerbates soleus muscle atrophy and weakness in phospholamban overexpressing mice. PLoS One 12, e0173708 (2017).

  • 備考:
    species: mouse, application: WB
  • 参照:
    PubMed
  • No.: 131
  • 文献情報:
    Aas, A. et al. Nucleocytoplasmic Shuttling of FTO Does Not Affect Starvation-Induced Autophagy. PLoS One 12, e0168182 (2017).

  • 備考:
    species: mouse, application: WB
  • 参照:
    PubMed
  • No.: 132
  • 文献情報:
    Ruf, S. et al. PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy. Autophagy 13, 486-505 (2017).

  • 備考:
    species: human, application: ICC-IF
  • 参照:
    PubMed
  • No.: 133
  • 文献情報:
    Nascimbeni, A. C., Fanin, M., Angelini, C. and Sandri, M. Autophagy dysregulation in Danon disease. Cell Death Dis. 8, e2565 (2017).

  • 備考:
    species: human, application: WB, IHC (frozen)
  • 参照:
    PubMed
  • No.: 134
  • 文献情報:
    Lee, M. Y. et al. Peroxisomal protein PEX13 functions in selective autophagy. EMBO Rep. 18, 48-60 (2017).

  • 備考:
    species: mouse, application: WB
  • 参照:
    PubMed
  • No.: 135
  • 文献情報:
    Sergin, I. et al. Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis. Nat. Commun. 8, 15750 (2017).

  • 備考:
    species: human, mouse, application: WB, IHC (frozen), ICC-IF
  • 参照:
    PubMed
  • No.: 136
  • 文献情報:
    Joachim, J. et al. Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy. Curr. Biol. 27, 2123-2136.e7 (2017).

  • 備考:
    species: human, application: ICC-IF
  • 参照:
    PubMed
  • No.: 137
  • 文献情報:
    Jacquier, A. et al. Cryptic amyloidogenic elements in mutant NEFH causing Charcot-Marie-Tooth 2 trigger aggresome formation and neuronal death. Acta Neuropathol. Commun. 5, 55 (2017).

  • 備考:
    species: human, chicken, application: IHC (frozen), ICC-IF
  • 参照:
    PubMed
  • No.: 138
  • 文献情報:
    Mildenberger, J. et al. N-3 PUFAs induce inflammatory tolerance by formation of KEAP1-containing SQSTM1/p62-bodies and activation of NFE2L2. Autophagy 00-00 (2017).

  • 備考:
    species: human, mouse, application: WB, ICC-IF
  • 参照:
    PubMed
  • No.: 139
  • 文献情報:
    Duleh, S., Wang, X., Komirenko, A. and Margeta, M. Activation of the Keap1/Nrf2 stress response pathway in autophagic vacuolar myopathies. Acta Neuropathol. Commun. 4, 115 (2016).

  • 備考:
    species: human, mouse, application: WB, IHC (frozen)
  • 参照:
    PubMed
  • No.: 140
  • 文献情報:
    Santanam, U. et al. Atg7 cooperates with Pten loss to drive prostate cancer tumor growth. Genes Dev. 30, 399-407 (2016).

  • 備考:
    species: mouse, application: IHC (frozen), ICC-IF
  • 参照:
    PubMed
  • No.: 141
  • 文献情報:
    Starheim, K. et al. Intracellular glutathione determines borte. cytotoxicity in multiple myeloma cells. Blood Cancer J. 6, (2016).

  • 備考:
    species: human, application: WB
  • 参照:
    PubMed
  • No.: 142
  • 文献情報:
    Yamanaka, T. et al. Differential roles of NF-Y transcription factor in ER chaperone expression and neuronal maintenance in the CNS. Nat. Publ. Gr. 6, (2016).

  • 備考:
    species: mouse, application: WB, IHC (frozen)
  • 参照:
    PubMed
  • No.: 143
  • 文献情報:
    Lim, S. W., Jin, L., Jin, J. and Yang, C. W. Effect of Exendin-4 on Autophagy Clearance in Beta Cell of Rats with Tacrolimus-induced Diabetes Mellitus. Nat. Publ. Gr. 6, (2016).

  • 備考:
    species: rat, application: WB, IHC (paraffin)
  • 参照:
    PubMed
  • No.: 144
  • 文献情報:
    Angelini, C., Nascimbeni, A. C., Cenacchi, G. and Tasca, E. Lipolysis and lipophagy in lipid storage myopathies. Biochim. Biophys. Acta 1367-1373 (2016).

  • 備考:
    species: human, application: WB, IHC (frozen)
  • 参照:
    PubMed
  • No.: 145
  • 文献情報:
    Corcelle-Termeau, E. et al. Excess sphingomyelin disturbs ATG9A trafficking and autophagosome closure. Autophagy 12, 533-849 (2016).

  • 備考:
    species: mouse, application: WB
  • 参照:
    PubMed
  • No.: 146
  • 文献情報:
    Ra, E. A. et al. TRIM31 promotes Atg5/Atg7-independent autophagy in intestinal cells. Nat. Commun. 7, (2016).

  • 備考:
    species: human, application: WB
  • 参照:
    PubMed
  • No.: 147
  • 文献情報:
    Kaizuka, T. and Mizushima, N. Atg13 Is Essential for Autophagy and Cardiac Development in Mice. Mol. Cell. Biol. 36, 585-595 (2016).

  • 備考:
    species: mouse, application: WB, ICC-IF
  • 参照:
    PubMed
  • No.: 148
  • 文献情報:
    Saito, T. et al. p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming. Nat. Commun. 7, (2016).

  • 備考:
    species: human, mouse, application: WB, IHC (paraffin)
  • 参照:
    PubMed
  • No.: 149
  • 文献情報:
    Jarvela, T. S. et al. The neural chaperone proSAAS blocks ホア-synuclein fibrillation and neurotoxicity. Proc. Natl. Acad. Sci. U. S. A. (2016).

  • 備考:
    species: human, application: IHC (frozen)
  • 参照:
    PubMed
  • No.: 150
  • 文献情報:
    Puvirajesinghe, T. M. et al. Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer. Nat. Commun. 7, (2016).

  • 備考:
    species: human, mouse, application: WB, ICC-IF
  • 参照:
    PubMed
  • No.: 151
  • 文献情報:
    Salas, E., Roy, S., Marsh, T., Rubin, B. and Debnath, J. Oxidative Pentose Phosphate Pathway Inhibition Is A Key Determinant of Antimalarial Induced Cancer Cell Death. Oncogene 35, 2913-2922 (2016).

  • 備考:
    species: mouse, application: ICC-IF
  • 参照:
    PubMed
  • No.: 152
  • 文献情報:
    Klionsky, D. J. et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12, 1 (2016).

  • 備考:
    species: mouse, application: WB
  • 参照:
    PubMed
  • No.: 153
  • 文献情報:
    Taneike, M. et al. mTOR Hyperactivation by Ablation of Tuberous Sclerosis Complex 2 in the Mouse Heart Induces Cardiac Dysfunction with the Increased Number of Small Mitochondria Mediated through the Down-Regulation of Autophagy. PLoS One 11, (2016).

  • 備考:
    species: mouse, application: WB
  • 参照:
    PubMed
  • No.: 154
  • 文献情報:
    Morimoto, D. et al. The unexpected role of polyubiquitin chains in the formation of fibrillar aggregates. Nat. Commun. 6, (2015).

  • 備考:
    species: mouse, application: WB, ICC-IF
  • 参照:
    PubMed
  • No.: 155
  • 文献情報:
    Milan, E. et al. A plastic SQSTM1/p62-dependent autophagic reserve maintains proteostasis and determines proteasome inhibitor susceptibility in multiple myeloma cells. Autophagy 11, 1161-1178 (2015).

  • 備考:
    species: human, application: WB, ICC-IF
  • 参照:
    PubMed
  • No.: 156
  • 文献情報:
    Larroquette, F. et al. Vapb/Amyotrophic lateral sclerosis 8 knock-in mice display slowly progressive motor behavior defects accompanying ER stress and autophagic response. Hum. Mol. Genet. 24, 6515-6529 (2015).

  • 備考:
    species: mouse, application: WB
  • 参照:
    PubMed
  • No.: 157
  • 文献情報:
    Hieke, N. et al. Expression of a ULK1/2 binding-deficient ATG13 variant can partially restore autophagic activity in ATG13-deficient cells. Autophagy 11, 1471-1483 (2015).

  • 備考:
    species: mouse, application: WB, ICC-IF
  • 参照:
    PubMed
  • No.: 158
  • 文献情報:
    Zhou, Z. et al. Autophagy supports color vision. Autophagy 11, 1821-1832 (2015).

  • 備考:
    species: mouse, application: IHC (frozen)
  • 参照:
    PubMed
  • No.: 159
  • 文献情報:
    Ciuffa, R. et al. The selective autophagy receptor p62 forms a flexible filamentous helical scaffold. Cell Rep. 11, 748-58 (2015).

  • 備考:
    species: human, application: WB
  • 参照:
    PubMed
  • No.: 160
  • 文献情報:
    Ulbricht, A. et al. Induction and adaptation of chaperone-assisted selective autophagy CASA in response to resistance exercise in human skeletal muscle. Autophagy 11, 538-546 (2015).

  • 備考:
    species: human, application: WB
  • 参照:
    PubMed
  • No.: 161
  • 文献情報:
    Murrow, L., Malhotra, R. and Debnath, J. ATG12-ATG3 Interacts with Alix to Promote Basal Autophagic Flux and Late Endosome Function. Nat. Cell Biol. 17, 300-310 (2015).

  • 備考:
    species: mouse, application: WB
  • 参照:
    PubMed
  • No.: 162
  • 文献情報:
    Lim, J. et al. Proteotoxic Stress Induces Phosphorylation of p62/SQSTM1 by ULK1 to Regulate Selective Autophagic Clearance of Protein Aggregates. PLoS One 11, (2015).

  • 備考:
    species: human, mouse, application: WB, ICC-IF
  • 参照:
    PubMed
  • No.: 163
  • 文献情報:
    Felzen, V. et al. Estrogen receptor ホア regulates non-canonical autophagy that provides stress resistance to neuroblastoma and breast cancer cells and involves BAG3 function. Cell Death Dis. 6, (2015).

  • 備考:
    species: human, application: ICC-IF
  • 参照:
    PubMed
  • No.: 164
  • 文献情報:
    Chandrachud, U. et al. Unbiased Cell-based Screening in a Neuronal Cell Model of Batten Disease Highlights an Interaction between Ca 2+ Homeostasis, Autophagy, and CLN3 Protein Function. J. Biol. Chem. 290, 14361-14380 (2015).

  • 備考:
    species: mouse, application: WB
  • 参照:
    PubMed
  • No.: 165
  • 文献情報:
    Liu, S. et al. Disrupted autophagy after spinal cord injury is associated with ER stress and neuronal cell death. Cell Death Dis. 6, (2015).

  • 備考:
    species: rat, application: WB, IHC (frozen)
  • 参照:
    PubMed
  • No.: 166
  • 文献情報:
    Johansson, I. et al. The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells. Autophagy 11, 1636-1651 (2015).

  • 備考:
    species: human, mouse, application: WB, ICC-IF
  • 参照:
    PubMed
  • No.: 167
  • 文献情報:
    Lodder, J. et al. Macrophage autophagy protects against liver fibrosis in mice. Autophagy 11, 1280-1292 (2015).

  • 備考:
    species: mouse, application: ICC-IF
  • 参照:
    PubMed
  • No.: 168
  • 文献情報:
    Agarwal, S. et al. Autophagy and endosomal trafficking inhibition by Vibrio cholerae MARTX toxin phosphatidylinositol- 3-phosphate-specific phospholipase A1 activity. Nat. Commun. 6, (2015).

  • 備考:
    species: human, application: WB
  • 参照:
    PubMed
  • No.: 169
  • 文献情報:
    Akizu, N. et al. Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction HHS Public Access. Nat. Genet. 47, 528-534 (2015).

  • 備考:
    species: human, application: WB
  • 参照:
    PubMed
  • No.: 170
  • 文献情報:
    Ruozi, G. et al. AAV-mediated in vivo functional selection of tissue-protective factors against ischaemia. Nat. Commun. 6, (2015).

  • 備考:
    species: mouse, application: WB
  • 参照:
    PubMed
  • No.: 171
  • 文献情報:
    Arel-Dubeau, A.-M. et al. Cucurbitacin E Has Neuroprotective Properties and Autophagic Modulating Activities on Dopaminergic Neurons. Oxid. Med. Cell. Longev. 2014, 15 (2015).

  • 備考:
    species: rat, application: WB
  • 参照:
    PubMed
  • No.: 172
  • 文献情報:
    Newton, P. T., Vuppalapati, K. K., Bouderlique, T. and Chagin, A. S. Pharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner. Autophagy 11, 1594-1607 (2015).

  • 備考:
    species: mouse, rat, application: WB
  • 参照:
    PubMed
  • No.: 173
  • 文献情報:
    Shi, J. et al. NBR1 is dispensable for PARK2-mediated mitophagy regardless of the presence or absence of SQSTM1. Cell Death Dis. 6, (2015).

  • 備考:
    species: human, application: WB
  • 参照:
    PubMed
  • No.: 174
  • 文献情報:
    Karlsson, A. B. et al. The role of spartin and its novel ubiquitin binding region in DALIS occurrence. Mol. Biol. Cell 25, 1355-1365 (2014).

  • 備考:
    species: mouse, application: ICC-IF
  • 参照:
    PubMed
  • No.: 175
  • 文献情報:
    Kinsey, C. et al. Plac8 links oncogenic mutations to regulation of autophagy and is critical to pancreatic cancer progression. Cell Rep. 7, 1143-1155 (2014).

  • 備考:
    species: human, mouse, application: WB
  • 参照:
    PubMed
  • No.: 176
  • 文献情報:
    McLendon, P. et al. An Unbiased High-Throughput Screen to Identify Novel Effectors That Impact on Cardiomyocyte Aggregate Levels. Circ.Res. 121, 604-616 (2017).

  • 備考:
  • 参照:
    PubMed
  • No.: 177
  • 文献情報:
    Glatigny, M. et al. Autophagy Is Required for Memory Formation and Reverses Age-Related Memory Decline. Curr.Biol. 29, 435-448.e8 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 178
  • 文献情報:
    Gorgulu, K. et al. Levels of the Autophagy-Related 5 Protein Affect Progression and Metastasis of Pancreatic Tumors in Mice. Gastroenterology. 156, 203-217.e20 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 179
  • 文献情報:
    Lim, J. et al. Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins. Elife. 8, (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 180
  • 文献情報:
    Lim, J. et al. Proteotoxic Stress Induces Phosphorylation of p62/SQSTM1 by ULK1 to Regulate Selective Autophagic Clearance of Protein Aggregates. PLoS One 11, (2015).

  • 備考:
  • 参照:
    PubMed
  • No.: 181
  • 文献情報:
    Yamada, T. et al. Prevention and regression of megamitochondria and steatosis by blocking mitochondrial fusion in the liver. iScience 25, 103996 (2022).

  • 備考:
  • 参照:
    PubMed
  • No.: 182
  • 文献情報:
    Gasset-Rosa, F. et al. Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death. Neuron. 102, 339-357.e7 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 183
  • 文献情報:
    Bonsi, P. et al. RGS9-2 rescues dopamine D2 receptor levels and signaling in DYT1 dystonia mouse models. EMBO.Mol.Med. 11, (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 184
  • 文献情報:
    Yamanaka, T. et al. NF-Y inactivation causes atypical neurodegeneration characterized by ubiquitin and p62 accumulation and endoplasmic reticulum disorganization. Nat. Commun. 5, (2014).

  • 備考:
  • 参照:
    PubMed
  • No.: 185
  • 文献情報:
    Yamano, K. & Youle, R. J. PINK1 is degraded through the N-end rule pathway. Autophagy 9, 1758–69 (2013).

  • 備考:
  • 参照:
    PubMed
  • No.: 186
  • 文献情報:
    Hegdekar N et al. N-Acetyl-L-leucine improves functional recovery and attenuates cortical cell death and neuroinflammation after traumatic brain injury in mice. Sci Rep 2021 Apr;11(1):9249
    Hegdekar N et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 187
  • 文献情報:
    Arel-Dubeau, A.-M. et al. Cucurbitacin E Has Neuroprotective Properties and Autophagic Modulating Activities on Dopaminergic Neurons. Oxid. Med. Cell. Longev. 2014, 15 (2015).

  • 備考:
  • 参照:
    PubMed
  • No.: 188
  • 文献情報:
    Zhang, J. et al. Cross-regulation of defective endolysosome trafficking and enhanced autophagy through TFEB in UNC13D deficiency. Autophagy. , 1-19 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 189
  • 文献情報:
    Kessler, S. et al. Diethylnitrosamine (DENA) recapitulates formation of hepatic angiosarcoma in pigs. PLoS.One. 14, e0214756 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 190
  • 文献情報:
    Fucci C et al. The Interaction of the Tumor Suppressor FAM46C with p62 and FNDC3 Proteins Integrates Protein and Secretory Homeostasis. Cell Rep 2020 Sep;32(12):108162
    Fucci C et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 191
  • 文献情報:
    Kivinen, N. The role of autophagy in age-related macular degeneration. Acta.Ophthalmol. 96 Suppl A110, Jan-50 (2018)

  • 備考:
  • 参照:
    PubMed
  • No.: 192
  • 文献情報:
    Hieke, N. et al. Expression of a ULK1/2 binding-deficient ATG13 variant can partially restore autophagic activity in ATG13-deficient cells. Autophagy 11, 1471–1483 (2015).

  • 備考:
  • 参照:
    PubMed
  • No.: 193
  • 文献情報:
    Metti S et al. The Polyphenol Pterostilbene Ameliorates the Myopathic Phenotype of Collagen VI Deficient Mice via Autophagy Induction. Front Cell Dev Biol 2020;8:580933
    Metti S et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 194
  • 文献情報:
    Akizu, N. et al. Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction HHS Public Access. Nat. Genet. 47, 528–534 (2015).

  • 備考:
  • 参照:
    PubMed
  • No.: 195
  • 文献情報:
    Shiba-Fukushima, K. et al. Evidence that phosphorylated ubiquitin signaling is involved in the etiology of Parkinson&quot;s disease. Hum.Mol.Genet. 26, 3172-3185 (2017)

  • 備考:
  • 参照:
    PubMed
  • No.: 196
  • 文献情報:
    Yamanaka, T. et al. Differential roles of NF-Y transcription factor in ER chaperone expression and neuronal maintenance in the CNS. Nat. Publ. Gr. 6, (2016).

  • 備考:
  • 参照:
    PubMed
  • No.: 197
  • 文献情報:
    Kiryu-Seo S et al. Impaired disassembly of the axon initial segment restricts mitochondrial entry into damaged axons. EMBO J 2022 Oct;41(20):e110486
    Kiryu-Seo S et al
    2022/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 198
  • 文献情報:
    Shimozawa, A. et al. Propagation of pathological 留-synuclein in marmoset brain. Acta Neuropathol. Commun. 5, 12 (2017)

  • 備考:
  • 参照:
    PubMed
  • No.: 199
  • 文献情報:
    Keller F et al. A Scaffold-Free 3-D Co-Culture Mimics the Major Features of the Reverse Warburg Effect In Vitro. Cells 2020 Aug;9(8)
    Keller F et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 200
  • 文献情報:
    Osonoi, Y. et al. Defective autophagy in vascular smooth muscle cells enhances cell death and atherosclerosis. Autophagy. 14, 1991-2006 (2018)

  • 備考:
  • 参照:
    PubMed
  • No.: 201
  • 文献情報:
    Rivera, J. F., Costes, S., Gurlo, T., Glabe, C. G. & Butler, P. C. Autophagy defends pancreatic β cells from human islet amyloid polypeptide-induced toxicity. J. Clin. Invest. 124, 3489–500 (2014).

  • 備考:
  • 参照:
    PubMed
  • No.: 202
  • 文献情報:
    Milan, E. et al. A plastic SQSTM1/p62-dependent autophagic reserve maintains proteostasis and determines proteasome inhibitor susceptibility in multiple myeloma cells. Autophagy 11, 1161–1178 (2015).

  • 備考:
  • 参照:
    PubMed
  • No.: 203
  • 文献情報:
    Mauthe, M. et al. Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion. Autophagy. 14, 1435-1455 (2018)

  • 備考:
  • 参照:
    PubMed
  • No.: 204
  • 文献情報:
    Kataura, T. et al. NDP52 acts as a redox sensor in PINK1/Parkin‐mediated mitophagy. EMBO J. e111372 (2022).

  • 備考:
  • 参照:
    PubMed
  • No.: 205
  • 文献情報:
    Rienzo, M. et al. Autophagy induction in atrophic muscle cells requires ULK1 activation by TRIM32 through unanchored K63-linked polyubiquitin chains. Sci.Adv. 5, eaau8857 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 206
  • 文献情報:
    Ozcelik, S. et al. Rapamycin Attenuates the Progression of Tau Pathology in P301S Tau Transgenic Mice. PLoS One 8, (2013)

  • 備考:
  • 参照:
    PubMed
  • No.: 207
  • 文献情報:
    Sargent, D. et al. Neuronal VPS35 deletion induces spinal cord motor neuron degeneration and early post-natal lethality . Brain Commun. 3, 1–20 (2021).

  • 備考:
  • 参照:
    PubMed
  • No.: 208
  • 文献情報:
    Eino, A. et al. Sqstm1-GFP knock-in mice reveal dynamic actions of Sqstm1 during autophagy and under stress conditions in living cells. J. Cell Sci. 128, 4453–61 (2015).

  • 備考:
  • 参照:
    PubMed
  • No.: 209
  • 文献情報:
    Deng, Z. et al. ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway. Autophagy. 16, 917-931 (2020)

  • 備考:
  • 参照:
    PubMed
  • No.: 210
  • 文献情報:
    Guan, B.-J. et al. Translational Control during Endoplasmic Reticulum Stress beyond Phosphorylation of the Translation Initiation Factor eIF2␣ *. J. Biol. Chem. 289, 12593–12611 (2014).

  • 備考:
  • 参照:
    PubMed
  • No.: 211
  • 文献情報:
    S叩nchez-L坦pez, E. et al. Choline Uptake and Metabolism Modulate Macrophage IL-1硫 and IL-18 Production. Cell.Metab. 29, 1350-1362.e7 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 212
  • 文献情報:
    Horigome, Y. et al. Loss of autophagy in chondrocytes causes severe growth retardation. Autophagy. , 1-11 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 213
  • 文献情報:
    Jiang, S., Guo, R., Zhang, Y., Zou, Y. & Ren, J. Heavy metal scavenger metallothionein mitigates deep hypothermia-induced myocardial contractile anomalies: role of autophagy. Am. J. Physiol. - Endocrinol. Metab. 304, (2013).

  • 備考:
  • 参照:
    PubMed
  • No.: 214
  • 文献情報:
    Kageyama, S. et al. Negative regulation of the Keap1-Nrf2 pathway by a p62/Sqstm1 splicing variant. Mol.Cell.Biol. ,  (2018).

  • 備考:
  • 参照:
    PubMed
  • No.: 215
  • 文献情報:
    Javaheri, A. et al. TFEB activation in macrophages attenuates postmyocardial infarction ventricular dysfunction independently of ATG5-mediated autophagy. JCI.Insight. 4, (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 216
  • 文献情報:
    Wallot-Hieke, N. et al. Systematic analysis of ATG13 domain requirements for autophagy induction. Autophagy. , 1-58 (2017)

  • 備考:
  • 参照:
    PubMed
  • No.: 217
  • 文献情報:
    Hill, C. et al. Autophagy inhibition-mediated epithelial-mesenchymal transition augments local myofibroblast differentiation in pulmonary fibrosis. Cell.Death.Dis. 10, 591 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 218
  • 文献情報:
    G坦mez-Sintes, R. et al. Standard Assays for the Study of Autophagy in the Ex Vivo Retina. Cells. 6, (2017)

  • 備考:
  • 参照:
    PubMed
  • No.: 219
  • 文献情報:
    Kinsey, C. et al. Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers. Nat.Med. 25, 620-627 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 220
  • 文献情報:
    Furuya, N. et al. PARK2/Parkin-mediated mitochondrial clearance contributes to proteasome activation during slow-twitch muscle atrophy via NFE2L1 nuclear translocation. Autophagy 10, 631–41 (2014).

  • 備考:
  • 参照:
    PubMed
  • No.: 221
  • 文献情報:
    Kaizuka, T. & Mizushima, N. Atg13 Is Essential for Autophagy and Cardiac Development in Mice. Mol. Cell. Biol. 36, 585–595 (2016).

  • 備考:
  • 参照:
    PubMed
  • No.: 222
  • 文献情報:
    Kinsey, C. et al. Plac8 links oncogenic mutations to regulation of autophagy and is critical to pancreatic cancer progression. Cell Rep. 7, 1143–1155 (2014).

  • 備考:
  • 参照:
    PubMed
  • No.: 223
  • 文献情報:
    Santanam, U. et al. Atg7 cooperates with Pten loss to drive prostate cancer tumor growth. Genes Dev. 30, 399–407 (2016).

  • 備考:
  • 参照:
    PubMed
  • No.: 224
  • 文献情報:
    Noman, M. et al. Inhibition of Vps34 reprograms cold into hot inflamed tumors and improves anti-PD-1/PD-L1 immunotherapy. Sci.Adv. 6, eaax7881 (2020)

  • 備考:
  • 参照:
    PubMed
  • No.: 225
  • 文献情報:
    Kurashige, T. et al. Hormonal Regulation of Autophagy in Thyroid PCCL3 Cells and the Thyroids of Male Mice. J.Endocr.Soc. 4, bvaa054 (2020)

  • 備考:
  • 参照:
    PubMed
  • No.: 226
  • 文献情報:
    Newton, P. T., Vuppalapati, K. K., Bouderlique, T. & Chagin, A. S. Pharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner. Autophagy 11, 1594–1607 (2015).

  • 備考:
  • 参照:
    PubMed
  • No.: 227
  • 文献情報:
    Ciuffa, R. et al. The selective autophagy receptor p62 forms a flexible filamentous helical scaffold. Cell Rep. 11, 748–58 (2015).

  • 備考:
  • 参照:
    PubMed
  • No.: 228
  • 文献情報:
    Nascimbeni, A. C., Fanin, M., Angelini, C. & Sandri, M. Autophagy dysregulation in Danon disease. Cell Death Dis. 8, e2565 (2017).

  • 備考:
  • 参照:
    PubMed
  • No.: 229
  • 文献情報:
    Sebori, R. et al. Resveratrol Decreases Oxidative Stress by Restoring Mitophagy and Improves the Pathophysiology of Dystrophin-Deficient mdx Mice. Oxid.Med.Cell.Longev. 2018, 9179270 (2018).

  • 備考:
  • 参照:
    PubMed
  • No.: 230
  • 文献情報:
    Nwadike, C. et al. AMPK Inhibits ULK1-Dependent Autophagosome Formation and Lysosomal Acidification via Distinct Mechanisms. Mol.Cell.Biol. 38,  (2018).

  • 備考:
  • 参照:
    PubMed
  • No.: 231
  • 文献情報:
    Angelini, C., Nascimbeni, A. C., Cenacchi, G. & Tasca, E. Lipolysis and lipophagy in lipid storage myopathies. Biochim. Biophys. Acta 1367–1373 (2016).

  • 備考:
  • 参照:
    PubMed
  • No.: 232
  • 文献情報:
    Pellegrini, C. et al. All-trans retinoic acid and rapamycin normalize Hutchinson Gilford progeria fibroblast phenotype. Oncotarget 6, 29914–29928 (2015).

  • 備考:
  • 参照:
    PubMed
  • No.: 233
  • 文献情報:
    Manzetti J et al. BK Polyomavirus Evades Innate Immune Sensing by Disrupting the Mitochondrial Network and Promotes Mitophagy. iScience 2020 Jul;23(7):101257
    Manzetti J et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 234
  • 文献情報:
    Aron, R. et al. Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington&quot;s disease. Nat.Commun. 9, 3191 (2018).

  • 備考:
  • 参照:
    PubMed
  • No.: 235
  • 文献情報:
    Schwob, A. et al. SQSTM-1/p62 potentiates HTLV-1 Tax-mediated NF-虜B activation through its ubiquitin binding function. Sci.Rep. 9, 16014 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 236
  • 文献情報:
    Lim, Y.-M. et al. Systemic autophagy insufficiency compromises adaptation to metabolic stress and facilitates progression from obesity to diabetes. Nat. Commun. 5, (2014).

  • 備考:
  • 参照:
    PubMed
  • No.: 237
  • 文献情報:
    Battista, R. et al. Autophagy mediates epithelial cancer chemoresistance by reducing p62/SQSTM1 accumulation. PLoS.One. 13, e0201621 (2018).

  • 備考:
  • 参照:
    PubMed
  • No.: 238
  • 文献情報:
    Nam, S. et al. Autophagy attenuates tubulointerstital fibrosis through regulating transforming growth factor-硫 and NLRP3 inflammasome signaling pathway. Cell.Death.Dis. 10, 78 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 239
  • 文献情報:
    Saito, T. et al. Autophagy regulates lipid metabolism through selective turnover of NCoR1. Nat.Commun. 10, 1567 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 240
  • 文献情報:
    Johansson, I. et al. The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells. Autophagy 11, 1636–1651 (2015).

  • 備考:
  • 参照:
    PubMed
  • No.: 241
  • 文献情報:
    Heijnen, H. F. et al. Ribosomal Protein Mutations Induce Autophagy through S6 Kinase Inhibition of the Insulin Pathway. PLoS Genet. 10, (2014).

  • 備考:
  • 参照:
    PubMed
  • No.: 242
  • 文献情報:
    Sample, A. et al. Adaptor protein p62 promotes skin tumor growth and metastasis and is induced by UVA radiation. J.Biol.Chem. 292, 14786-14795 (2017).

  • 備考:
  • 参照:
    PubMed
  • No.: 243
  • 文献情報:
    Gallagher, L. et al. Lysosomotropism depends on glucose: a chloroquine resistance mechanism. Cell.Death.Dis. 8, e3014 (2017).

  • 備考:
  • 参照:
    PubMed
  • No.: 244
  • 文献情報:
    Aubert, P. et al. Maternal protein restriction induces gastrointestinal dysfunction and enteric nervous system remodeling in rat offspring. FASEB.J. 33, 770-781 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 245
  • 文献情報:
    Yang, Y. et al. Cytoplasmic DAXX drives SQSTM1/p62 phase condensation to activate Nrf2-mediated stress response. Nat.Commun. 10, 3759 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 246
  • 文献情報:
    Jackson, J. et al. SGPL1 stimulates VPS39 recruitment to the mitochondria in MICU1 deficient cells. Mol. Metab. 61, 101503 (2022).

  • 備考:
  • 参照:
    PubMed
  • No.: 247
  • 文献情報:
    Sarkar, C. et al. PLA2G4A/cPLA2-mediated lysosomal membrane damage leads to inhibition of autophagy and neurodegeneration after brain trauma. Autophagy. , 1-20 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 248
  • 文献情報:
    Conte, A. et al. High mobility group A1 protein modulates autophagy in cancer cells. Cell.Death.Differ. 24, 1948-1962 (2017).

  • 備考:
  • 参照:
    PubMed
  • No.: 249
  • 文献情報:
    Jung, S. et al. Buffering of cytosolic calcium plays a neuroprotective role by preserving the autophagy-lysosome pathway during MPP+-induced neuronal death. Cell.Death.Discov. 5, 130 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 250
  • 文献情報:
    Sergin, I. et al. Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis. Nat. Commun. 8, 15750 (2017).

  • 備考:
  • 参照:
    PubMed
  • No.: 251
  • 文献情報:
    Miret-Casals, L. et al. Identification of New Activators of Mitochondrial Fusion Reveals a Link between Mitochondrial Morphology and Pyrimidine Metabolism. Cell.Chem.Biol. 25, 268-278.e4 (2018)

  • 備考:
  • 参照:
    PubMed
  • No.: 252
  • 文献情報:
    Over奪, K. et al. TRIM32, but not its muscular dystrophy-associated mutant, positively regulates and is targeted to autophagic degradation by p62/SQSTM1. J.Cell.Sci. 132, (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 253
  • 文献情報:
    Riemschoss, K. et al. Fibril-induced glutamine-/asparagine-rich prions recruit stress granule proteins in mammalian cells. Life.Sci.Alliance. 2, (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 254
  • 文献情報:
    Kondylis, V. et al. Endosome-mediated autophagy: an unconventional MIIC-driven autophagic pathway operational in dendritic cells. Autophagy 9, 861–80 (2013).

  • 備考:
  • 参照:
    PubMed
  • No.: 255
  • 文献情報:
    Saito, T. et al. p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming. Nat. Commun. 7, (2016).

  • 備考:
  • 参照:
    PubMed
  • No.: 256
  • 文献情報:
    Birgisdottir, Å. et al. Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs. Autophagy. , Jan-23 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 257
  • 文献情報:
    Nicot, A.-S. et al. Phosphorylation of NBR1 by GSK3 modulates protein aggregation. Autophagy 10, 1036–53 (2014).

  • 備考:
  • 参照:
    PubMed
  • No.: 258
  • 文献情報:
    Sato, S. et al. Loss of autophagy in dopaminergic neurons causes Lewy pathology and motor dysfunction in aged mice. Sci.Rep. 8, 2813 (2018)

  • 備考:
  • 参照:
    PubMed
  • No.: 259
  • 文献情報:
    Koyuncu, S. et al. The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington&quot;s disease patients. Nat.Commun. 9, 2886 (2018).

  • 備考:
  • 参照:
    PubMed
  • No.: 260
  • 文献情報:
    Deitersen J et al. High-throughput screening for natural compound-based autophagy modulators reveals novel chemotherapeutic mode of action for arzanol. Cell Death Dis 2021 May;12(6):560
    Deitersen J et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 261
  • 文献情報:
    Pellegrini, C. et al. Altered adipocyte differentiation and unbalanced autophagy in type 2 Familial Partial Lipodystrophy: an in vitro and in vivo study of adipose tissue browning. Exp.Mol.Med. 51, 89 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 262
  • 文献情報:
    McLelland, G. et al. Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy. Elife. 7,  (2018).

  • 備考:
  • 参照:
    PubMed
  • No.: 263
  • 文献情報:
    Lenoir, O. et al. Endothelial cell and podocyte autophagy synergistically protect from diabetes-induced glomerulosclerosis. Autophagy 11, 1130–45 (2015).

  • 備考:
  • 参照:
    PubMed
  • No.: 264
  • 文献情報:
    Lee, M. Y. et al. Peroxisomal protein PEX13 functions in selective autophagy. EMBO Rep. 18, 48–60 (2017).

  • 備考:
  • 参照:
    PubMed
  • No.: 265
  • 文献情報:
    Tang, T. et al. Dihydroartemisinin and its anticancer activity against endometrial carcinoma and cervical cancer: involvement of apoptosis, autophagy and transferrin receptor. Singapore.Med.J. , (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 266
  • 文献情報:
    Chakraborty, D. et al. Enhanced autophagic-lysosomal activity and increased BAG3-mediated selective macroautophagy as adaptive response of neuronal cells to chronic oxidative stress. Redox.Biol. 24, 101181 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 267
  • 文献情報:
    Jakobi, A. et al. Structural basis of p62/SQSTM1 helical filaments and their role in cellular cargo uptake. Nat.Commun. 11, 440 (2020)

  • 備考:
  • 参照:
    PubMed
  • No.: 268
  • 文献情報:
    Vincent, A. et al. Subcellular origin of mitochondrial DNA deletions in human skeletal muscle. Ann.Neurol. 84, 289-301 (2018).

  • 備考:
  • 参照:
    PubMed
  • No.: 269
  • 文献情報:
    Clayton, E. L. et al. Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology. Acta Neuropathol. 130, 511–23 (2015).

  • 備考:
  • 参照:
    PubMed
  • No.: 270
  • 文献情報:
    Salas, E., Roy, S., Marsh, T., Rubin, B. & Debnath, J. Oxidative Pentose Phosphate Pathway Inhibition Is A Key Determinant of Antimalarial Induced Cancer Cell Death. Oncogene 35, 2913–2922 (2016).

  • 備考:
  • 参照:
    PubMed
  • No.: 271
  • 文献情報:
    Murrow, L., Malhotra, R. & Debnath, J. ATG12-ATG3 Interacts with Alix to Promote Basal Autophagic Flux and Late Endosome Function. Nat. Cell Biol. 17, 300–310 (2015).

  • 備考:
  • 参照:
    PubMed
  • No.: 272
  • 文献情報:
    Matta, S. et al. NADPH Oxidase and Guanylate Binding Protein 5 Restrict Survival of Avirulent Type III Strains of Toxoplasma gondii in Naive Macrophages. MBio. 9,  (2018).

  • 備考:
  • 参照:
    PubMed
  • No.: 273
  • 文献情報:
    Viana-Huete, V. et al. Male Brown Fat-Specific Double Knockout of IGFIR/IR: Atrophy, Mitochondrial Fission Failure, Impaired Thermogenesis, and Obesity. Endocrinology. 159, 323-340 (2018)

  • 備考:
  • 参照:
    PubMed
  • No.: 274
  • 文献情報:
    Agarwal, S. et al. Autophagy and endosomal trafficking inhibition by Vibrio cholerae MARTX toxin phosphatidylinositol- 3-phosphate-specific phospholipase A1 activity. Nat. Commun. 6, (2015).

  • 備考:
  • 参照:
    PubMed
  • No.: 275
  • 文献情報:
    Cottam, E. M., Whelband, M. C. & Wileman, T. Coronavirus NSP6 restricts autophagosome expansion. Autophagy 10, (2014).

  • 備考:
  • 参照:
    PubMed
  • No.: 276
  • 文献情報:
    Wang, Y. et al. Autophagy inhibition specifically promotes epithelial-mesenchymal transition and invasion in RAS-mutated cancer cells. Autophagy. , Jan-14 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 277
  • 文献情報:
    Echeverry, N. et al. Inhibition of autophagy sensitizes malignant pleural mesothelioma cells to dual PI3K/mTOR inhibitors. Cell Death Dis. 6, (2015).

  • 備考:
  • 参照:
    PubMed
  • No.: 278
  • 文献情報:
    Fern叩ndez, A. et al. Disruption of the beclin 1-BCL2 autophagy regulatory complex promotes longevity in mice. Nature. 558, 136-140 (2018)

  • 備考:
  • 参照:
    PubMed
  • No.: 279
  • 文献情報:
    Klionsky, D. J. et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12, 1 (2016).

  • 備考:
  • 参照:
    PubMed
  • No.: 280
  • 文献情報:
    Sebastiani, A. et al. Sequestosome 1 Deficiency Delays, but Does Not Prevent Brain Damage Formation Following Acute Brain Injury in Adult Mice. Front.Neurosci. 11, 678 (2018).

  • 備考:
  • 参照:
    PubMed
  • No.: 281
  • 文献情報:
    Park, S. et al. A lysosomal chloride ion-selective fluorescent probe for biological applications. Chem.Sci. 10, 56-66 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 282
  • 文献情報:
    Gurlo, T. et al. Pregnancy in human IAPP transgenic mice recapitulates beta cell stress in type 2 diabetes. Diabetologia. 62, 1000-1010 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 283
  • 文献情報:
    Carballo-Carbajal, I. et al. Brain tyrosinase overexpression implicates age-dependent neuromelanin production in Parkinson&quot;s disease pathogenesis. Nat.Commun. 10, 973 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 284
  • 文献情報:
    Saegusa, C. et al. Low-dose rapamycin-induced autophagy in cochlear outer sulcus cells.. Laryngoscope Investig Otolaryngol. 5, 520-528(2020).

  • 備考:
  • 参照:
    PubMed
  • No.: 285
  • 文献情報:
    Ulbricht, A. et al. Induction and adaptation of chaperone-assisted selective autophagy CASA in response to resistance exercise in human skeletal muscle. Autophagy 11, 538–546 (2015).

  • 備考:
  • 参照:
    PubMed
  • No.: 286
  • 文献情報:
    Ruozi, G. et al. AAV-mediated in vivo functional selection of tissue-protective factors against ischaemia. Nat. Commun. 6, (2015).

  • 備考:
  • 参照:
    PubMed
  • No.: 287
  • 文献情報:
    Starheim, K. et al. Intracellular glutathione determines borte. cytotoxicity in multiple myeloma cells. Blood Cancer J. 6, (2016).

  • 備考:
  • 参照:
    PubMed
  • No.: 288
  • 文献情報:
    Livingston, J. et al. Analysis of HSP27 and the Autophagy Marker LC3B+ Puncta Following Preoperative Chemotherapy Identifies High-Risk Osteosarcoma Patients. Mol.Cancer.Ther. 17, 1315-1323 (2018)

  • 備考:
  • 参照:
    PubMed
  • No.: 289
  • 文献情報:
    Werner, G. et al. Loss of TMEM106B potentiates lysosomal and FTLD-like pathology in progranulin-deficient mice. EMBO Rep. 21, e50241(2020).

  • 備考:
  • 参照:
    PubMed
  • No.: 290
  • 文献情報:
    Zhou, Z. et al. Autophagy supports color vision. Autophagy 11, 1821–1832 (2015).

  • 備考:
  • 参照:
    PubMed
  • No.: 291
  • 文献情報:
    Hartupee, J. et al. Impaired Protein Quality Control During Left Ventricular Remodeling in Mice With Cardiac Restricted Overexpression of Tumor Necrosis Factor. Circ.Heart.Fail. 10,  (2017).

  • 備考:
  • 参照:
    PubMed
  • No.: 292
  • 文献情報:
    Dunlop, E. A. et al. FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation. Autophagy 10, 1749–1760 (2014).

  • 備考:
  • 参照:
    PubMed
  • No.: 293
  • 文献情報:
    Lim, S. W., Jin, L., Jin, J. & Yang, C. W. Effect of Exendin-4 on Autophagy Clearance in Beta Cell of Rats with Tacrolimus-induced Diabetes Mellitus. Nat. Publ. Gr. 6, (2016).

  • 備考:
  • 参照:
    PubMed
  • No.: 294
  • 文献情報:
    Giaime, E. et al. Age-Dependent Dopaminergic Neurodegeneration and Impairment of the Autophagy-Lysosomal Pathway in LRRK-Deficient Mice. Neuron. 96, 796-807.e6 (2017)

  • 備考:
  • 参照:
    PubMed
  • No.: 295
  • 文献情報:
    Ra, E. A. et al. TRIM31 promotes Atg5/Atg7-independent autophagy in intestinal cells. Nat. Commun. 7, (2016).

  • 備考:
  • 参照:
    PubMed
  • No.: 296
  • 文献情報:
    Costes, S., Gurlo, T., Rivera, J. F. & Butler, P. C. UCHL1 deficiency exacerbates human islet amyloid polypeptide toxicity in β-cells: evidence of interplay between the ubiquitin/proteasome system and autophagy. Autophagy 10, 1004–14 (2014).

  • 備考:
  • 参照:
    PubMed
  • No.: 297
  • 文献情報:
    Schober, A. et al. Cell Loss and Autophagy in the Extra‐Adrenal Chromaffin Organ of Zuckerkandl are Regulated by Glucocorticoid Signalling. J. Neuroendocrinol. 25, 34–47 (2013)

  • 備考:
  • 参照:
    PubMed
  • No.: 298
  • 文献情報:
    Ogmundsd坦ttir, M. et al. A short isoform of ATG7 fails to lipidate LC3/GABARAP. Sci.Rep. 8, 14391 (2018).

  • 備考:
  • 参照:
    PubMed
  • No.: 299
  • 文献情報:
    Liu, S. et al. Disrupted autophagy after spinal cord injury is associated with ER stress and neuronal cell death. Cell Death Dis. 6, (2015).

  • 備考:
  • 参照:
    PubMed
  • No.: 300
  • 文献情報:
    Igawa, H. et al. p62-mediated autophagy affects nutrition-dependent insulin receptor substrate 1 dynamics in 3T3-L1 preadipocytes. J.Diabetes.Investig. 10, 32-42 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 301
  • 文献情報:
    Corcelle-Termeau, E. et al. Excess sphingomyelin disturbs ATG9A trafficking and autophagosome closure. Autophagy 12, 533–849 (2016)

  • 備考:
  • 参照:
    PubMed
  • No.: 302
  • 文献情報:
    Duleh, S., Wang, X., Komirenko, A. & Margeta, M. Activation of the Keap1/Nrf2 stress response pathway in autophagic vacuolar myopathies. Acta Neuropathol. Commun. 4, 115 (2016).

  • 備考:
  • 参照:
    PubMed
  • No.: 303
  • 文献情報:
    Himuro, M. et al. Cellular Autophagy in 留 Cells Plays a Role in the Maintenance of Islet Architecture. J.Endocr.Soc. 3, 1979-1992 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 304
  • 文献情報:
    Sergin, I. et al. p62-enriched inclusion bodies in macrophages protect against atherosclerosis HHS Public Access. Sci. Signal. 9, (2016).

  • 備考:
  • 参照:
    PubMed
  • No.: 305
  • 文献情報:
    Castets, P. et al. mTORC1 and PKB/Akt control the muscle response to denervation by regulating autophagy and HDAC4. Nat.Commun. 10, 3187 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 306
  • 文献情報:
    Nascimbeni, A. et al. Local detection of PtdIns3P at autophagosome biogenesis membrane platforms. Autophagy. 13, 1602-1612 (2017).

  • 備考:
  • 参照:
    PubMed
  • No.: 307
  • 文献情報:
    Carroll, B. et al. Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis. Nat.Commun. 9, 256 (2018).

  • 備考:
  • 参照:
    PubMed
  • No.: 308
  • 文献情報:
    Schmitz K et al. An essential role of the autophagy activating kinase ULK1 in snRNP biogenesis. Nucleic Acids Res 2021 06;49(11):6437-6455
    Schmitz K et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 309
  • 文献情報:
    Spilman, P. et al. Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer’s Disease. PLoS One 5, e9979 (2010).

  • 備考:
  • 参照:
    PubMed
  • No.: 310
  • 文献情報:
    Baeken MW et al. Novel Insights into the Cellular Localization and Regulation of the Autophagosomal Proteins LC3A, LC3B and LC3C. Cells 2020 10;9(10)
    Baeken MW et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 311
  • 文献情報:
    Alam, S. et al. Aberrant Mitochondrial Fission Is Maladaptive in Desmin Mutation-Induced Cardiac Proteotoxicity. J.Am.Heart.Assoc. 7,  (2018).

  • 備考:
  • 参照:
    PubMed
  • No.: 312
  • 文献情報:
    Klimek, C. et al. The Hippo network kinase STK38 contributes to protein homeostasis by inhibiting BAG3-mediated autophagy. Biochim. Biophys. Acta - Mol. Cell Res. 1866, 1556–1566 (2019).

  • 備考:
  • 参照:
    PubMed
  • No.: 313
  • 文献情報:
    Feldmann, A. et al. The RAB GTPase RAB18 modulates macroautophagy and proteostasis. Biochem. Biophys. Res. Commun. 486, 738–743 (2017).

  • 備考:
  • 参照:
    PubMed
  • No.: 314
  • 文献情報:
    Yuan, H.-X., Russell, R. C. & Guan, K.-L. Regulation of PIK3C3/VPS34 complexes by MTOR in nutrient stress-induced autophagy. Autophagy 9, 1983–95 (2013).

  • 備考:
  • 参照:
    PubMed
  • No.: 315
  • 文献情報:
    Oehl, K. et al. Live-Cell Mesothelioma Biobank to Explore Mechanisms of Tumor Progression. Front.Oncol. 8, 40 (2018).

  • 備考:
  • 参照:
    PubMed
  • No.: 316
  • 文献情報:
    Kakimoto, Y. et al. Myocardial cathepsin D is downregulated in sudden cardiac death. PLoS.One. 15, e0230375 (2020)

  • 備考:
  • 参照:
    PubMed
  • No.: 317
  • 文献情報:
    Ma, X. et al. Transcription Factor EB Activation Rescues Advanced 留B-Crystallin Mutation-Induced Cardiomyopathy by Normalizing Desmin Localization. J.Am.Heart.Assoc. 8, e010866 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 318
  • 文献情報:
    Yanagisawa, H. et al. L-leucine and SPNS1 coordinately ameliorate dysfunction of autophagy in mouse and human Niemann-Pick type C disease. Sci.Rep. 7, 15944 (2017).

  • 備考:
  • 参照:
    PubMed
  • No.: 319
  • 文献情報:
    Aishwarya, R. et al. Pleiotropic effects of mdivi-1 in altering mitochondrial dynamics, respiration, and autophagy in cardiomyocytes. Redox Biol. 36, 101660(2020).

  • 備考:
  • 参照:
    PubMed
  • No.: 320
  • 文献情報:
    Nozaki, M. et al. SQSTM1L341V variant that is linked to sporadic ALS exhibits impaired association with MAP1LC3 in cultured cells. eNeurologicalSci. 22, 100301(2021).

  • 備考:
  • 参照:
    PubMed
  • No.: 321
  • 文献情報:
    Chandrachud, U. et al. Unbiased Cell-based Screening in a Neuronal Cell Model of Batten Disease Highlights an Interaction between Ca 2+ Homeostasis, Autophagy, and CLN3 Protein Function. J. Biol. Chem. 290, 14361–14380 (2015).

  • 備考:
  • 参照:
    PubMed
  • No.: 322
  • 文献情報:
    Leidal, A. et al. The LC3-conjugation machinery specifies the loading of RNA-binding proteins into extracellular vesicles. Nat.Cell.Biol. 22, 187-199 (2020)

  • 備考:
  • 参照:
    PubMed
  • No.: 323
  • 文献情報:
    Fung, G. et al. Phosphorylation and degradation of 留B-crystallin during enterovirus infection facilitates viral replication and induces viral pathogenesis. Oncotarget. 8, 74767-74780 (2017).

  • 備考:
  • 参照:
    PubMed
  • No.: 324
  • 文献情報:
    Bhushan J et al. ISG15 Connects Autophagy and IFN-&#x3B3;-Dependent Control of Toxoplasma gondii Infection in Human Cells. mBio 2020 10;11(5)
    Bhushan J et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 325
  • 文献情報:
    Kim, W. et al. Atg7-dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokalemia. Sci.Rep. 9, 3021 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 326
  • 文献情報:
    Mishra, P. et al. Discovery of pan autophagy inhibitors through a high-throughput screen highlights macroautophagy as an evolutionarily conserved process across 3 eukaryotic kingdoms. Autophagy. 13, 1556-1572 (2017).

  • 備考:
  • 参照:
    PubMed
  • No.: 327
  • 文献情報:
    Cui, Y. H. et al. Autophagy of the m6A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis. Nat. Commun. 12, 1–19 (2021).

  • 備考:
  • 参照:
    PubMed
  • No.: 328
  • 文献情報:
    Kravic, B. et al. In mammalian skeletal muscle, phosphorylation of TOMM22 by protein kinase CSNK2/CK2 controls mitophagy. Autophagy. 14, 311-335 (2017)

  • 備考:
  • 参照:
    PubMed
  • No.: 329
  • 文献情報:
    Dubois, C. et al. Co-targeting Mitochondrial Ca2+ Homeostasis and Autophagy Enhances Cancer Cells&quot; Chemosensitivity. iScience. 23, 101263(2020).

  • 備考:
  • 参照:
    PubMed
  • No.: 330
  • 文献情報:
    Yang, S. et al. m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade. Nat.Commun. 10, 2782 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 331
  • 文献情報:
    Choi, I. et al. Microglia clear neuron-released 留-synuclein via selective autophagy and prevent neurodegeneration. Nat.Commun. 11, 1386 (2020)

  • 備考:
  • 参照:
    PubMed
  • No.: 332
  • 文献情報:
    Bartolomeo, R. et al. mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy. J.Clin.Invest. 127, 3717-3729 (2017)

  • 備考:
  • 参照:
    PubMed
  • No.: 333
  • 文献情報:
    Liang, S. et al. Murine macrophage autophagy protects against alcohol-induced liver injury by degrading interferon regulatory factor 1 (IRF1) and removing damaged mitochondria. J.Biol.Chem. , (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 334
  • 文献情報:
    Kuno, A. et al. Resveratrol Ameliorates Mitophagy Disturbance and Improves Cardiac Pathophysiology of Dystrophin-deficient mdx Mice. Sci.Rep. 8, 15555 (2018).

  • 備考:
  • 参照:
    PubMed
  • No.: 335
  • 文献情報:
    Tamura, N. et al. Hyperosmotic stress induces unconventional autophagy independent of the Ulk1 complex. Mol.Cell.Biol. , (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 336
  • 文献情報:
    Wu, Z. et al. Ubiquitination of ABCE1 by NOT4 in Response to Mitochondrial Damage Links Co-translational Quality Control to PINK1-Directed Mitophagy. Cell.Metab. 28, 130-144.e7 (2018)

  • 備考:
  • 参照:
    PubMed
  • No.: 337
  • 文献情報:
    Glenn JK et al. Task delegation to physician extenders--some comparisons. Am J Public Health 1976 Jan;66(1):64-6
    Glenn JK et al
    1976/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 338
  • 文献情報:
    Jacquier, A. et al. Cryptic amyloidogenic elements in mutant NEFH causing Charcot-Marie-Tooth 2 trigger aggresome formation and neuronal death. Acta Neuropathol. Commun. 5, 55 (2017).

  • 備考:
  • 参照:
    PubMed
  • No.: 339
  • 文献情報:
    Achour, I. et al. Oleuropein Prevents Neuronal Death, Mitigates Mitochondrial Superoxide Production and Modulates Autophagy in a Dopaminergic Cellular Model. Int. J. Mol. Sci. 17, 1293 (2016)

  • 備考:
  • 参照:
    PubMed
  • No.: 340
  • 文献情報:
    Furuya, N. et al. NDP52 interacts with mitochondrial RNA poly(A) polymerase to promote mitophagy. EMBO.Rep. 19, (2018)

  • 備考:
  • 参照:
    PubMed
  • No.: 341
  • 文献情報:
    Puvirajesinghe, T. M. et al. Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer. Nat. Commun. 7, (2016).

  • 備考:
  • 参照:
    PubMed
  • No.: 342
  • 文献情報:
    Karlsson, A. B. et al. The role of spartin and its novel ubiquitin binding region in DALIS occurrence. Mol. Biol. Cell 25, 1355–1365 (2014).

  • 備考:
  • 参照:
    PubMed
  • No.: 343
  • 文献情報:
    Baranowska, K. et al. Hydroxychloroquine potentiates carfilzomib toxicity towards myeloma cells. Oncotarget 7, 70845–70856 (2016)

  • 備考:
  • 参照:
    PubMed
  • No.: 344
  • 文献情報:
    Varea, O., Guinovart, J. J. & Duran, J. Malin restoration as proof of concept for gene therapy for Lafora disease. Brain Commun. 4, (2022).

  • 備考:
  • 参照:
    PubMed
  • No.: 345
  • 文献情報:
    Aas, A. et al. Nucleocytoplasmic Shuttling of FTO Does Not Affect Starvation-Induced Autophagy. PLoS One 12, e0168182 (2017).

  • 備考:
  • 参照:
    PubMed
  • No.: 346
  • 文献情報:
    Pigna, E. et al. Histone deacetylase 4 protects from denervation and skeletal muscle atrophy in a murine model of amyotrophic lateral sclerosis. EBioMedicine. 40, 717-732 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 347
  • 文献情報:
    Schl端termann D et al. FIP200 controls the TBK1 activation threshold at SQSTM1/p62-positive condensates. Sci Rep 2021 Jul;11(1):13863
    Schl端termann D et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 348
  • 文献情報:
    Cabe, M. et al. PB1 and UBA domains of p62 are essential for aggresome-like induced structure formation. Biochem.Biophys.Res.Commun. 503, 2306-2311 (2018)

  • 備考:
  • 参照:
    PubMed
  • No.: 349
  • 文献情報:
    Takahashi, M. et al. USP10 Is a Driver of Ubiquitinated Protein Aggregation and Aggresome Formation to Inhibit Apoptosis. iScience. 9, 433-450 (2018).

  • 備考:
  • 参照:
    PubMed
  • No.: 350
  • 文献情報:
    Garcia, D. et al. Genetic Liver-Specific AMPK Activation Protects against Diet-Induced Obesity and NAFLD. Cell.Rep. 26, 192-208.e6 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 351
  • 文献情報:
    Zatloukal, B. et al. Sensitivity and specificity of in situ proximity ligation for protein interaction analysis in a model of steatohepatitis with mallory-denk bodies. PLoS One 9, (2014).

  • 備考:
  • 参照:
    PubMed
  • No.: 352
  • 文献情報:
    Vanzo, R. et al. Autophagy role(s) in response to oncogenes and DNA replication stress. Cell.Death.Differ. , (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 353
  • 文献情報:
    Joachim, J. et al. Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy. Curr. Biol. 27, 2123–2136.e7 (2017).

  • 備考:
  • 参照:
    PubMed
  • No.: 354
  • 文献情報:
    Lachance, V. et al. Autophagy protein NRBF2 has reduced expression in Alzheimer&quot;s brains and modulates memory and amyloid-beta homeostasis in mice. Mol.Neurodegener. 14, 43 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 355
  • 文献情報:
    Shackelford, D. B. et al. LKB1 inactivation dictates therapeutic response of non-small cell lung cancer to the metabolism drug phenformin. Cancer Cell 23, 143–58 (2013).

  • 備考:
  • 参照:
    PubMed
  • No.: 356
  • 文献情報:
    Ruf, S. et al. PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy. Autophagy 13, 486–505 (2017).

  • 備考:
  • 参照:
    PubMed
  • No.: 357
  • 文献情報:
    Vargas, T. et al. Selective degradation of PU.1 during autophagy represses the differentiation and antitumour activity of TH9 cells. Nat.Commun. 8, 559 (2017).

  • 備考:
  • 参照:
    PubMed
  • No.: 358
  • 文献情報:
    Kondratskyi, A. et al. Identification of ML-9 as a lysosomotropic agent targeting autophagy and cell death. Cell Death Dis. 5, (2014).

  • 備考:
  • 参照:
    PubMed
  • No.: 359
  • 文献情報:
    Solvik TA et al. Secretory autophagy maintains proteostasis upon lysosome inhibition. J Cell Biol 2022 Jun;221(6)
    Solvik TA et al
    2022/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 360
  • 文献情報:
    Kakuta, S. et al. Small GTPase Rab1B is associated with ATG9A vesicles and regulates autophagosome formation. FASEB.J. 31, 3757-3773 (2017)

  • 備考:
  • 参照:
    PubMed
  • No.: 361
  • 文献情報:
    Nthiga TM et al. Regulation of Golgi turnover by CALCOCO1-mediated selective autophagy. J Cell Biol 2021 Jun;220(6)
    Nthiga TM et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 362
  • 文献情報:
    Anisimov, S. et al. G3BP1 inhibits ubiquitinated protein aggregations induced by p62 and USP10. Sci.Rep. 9, 12896 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 363
  • 文献情報:
    Larroquette, F. et al. Vapb/Amyotrophic lateral sclerosis 8 knock-in mice display slowly progressive motor behavior defects accompanying ER stress and autophagic response. Hum. Mol. Genet. 24, 6515–6529 (2015).

  • 備考:
  • 参照:
    PubMed
  • No.: 364
  • 文献情報:
    Gabandé-Rodrıuez, E., Boya, P., Labrador, V., Dotti, C. & Ledesma, M. High sphingomyelin levels induce lysosomal damage and autophagy dysfunction in N324ann Pick disease type A. Cell Death Differ. 21, 864–875 (2014).

  • 備考:
  • 参照:
    PubMed
  • No.: 365
  • 文献情報:
    Cui, D. et al. Impaired autophagosome clearance contributes to neuronal death in a piglet model of neonatal hypoxic-ischemic encephalopathy. Cell Death Dis. 8, e2919 (2017)

  • 備考:
  • 参照:
    PubMed
  • No.: 366
  • 文献情報:
    Nikam, A. et al. The PPAR留 Agonist Fenofibrate Prevents Formation of Protein Aggregates (Mallory-Denk bodies) in a Murine Model of Steatohepatitis-like Hepatotoxicity. Sci.Rep. 8, 12964 (2018).

  • 備考:
  • 参照:
    PubMed
  • No.: 367
  • 文献情報:
    Qiang, L. et al. Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis. Autophagy. 13, 2086-2103 (2017)

  • 備考:
  • 参照:
    PubMed
  • No.: 368
  • 文献情報:
    Yanagisawa, H. et al. L-leucine and SPNS1 coordinately ameliorate dysfunction of autophagy in mouse and human N324ann-Pick type C disease. Sci.Rep. 7, 15944 (2017).

  • 備考:
  • 参照:
    PubMed
  • No.: 369
  • 文献情報:
    Puvirajesinghe, T. M. et al. Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2窶笛NK signalling in breast cancer. Nat. Commun. 7, (2016).

  • 備考:
  • 参照:
    PubMed
  • No.: 370
  • 文献情報:
    Sahani, M. H., Itakura, E. & Mizushima, N. Expression of the autophagy substrate SQSTM1/p62 is restored during prolonged starvation depending on transcriptional upregulation and autophagy-derived amino acids. Autophagy 10, 431–41 (2014).

  • 備考:
  • 参照:
    PubMed
  • No.: 371
  • 文献情報:
    Sharma K et al. Autophagy modulates cell fate decisions during lineage commitment. Autophagy 2022 Aug;18(8):1915-1931
    Sharma K et al
    2022/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 372
  • 文献情報:
    S淡nder SL et al. Restructuring of the plasma membrane upon damage by LC3-associated macropinocytosis. Sci Adv 2021 Jul;7(27)
    S淡nder SL et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 373
  • 文献情報:
    Pasquier, A. et al. Lysosomal degradation of newly formed insulin granules contributes to 硫 cell failure in diabetes. Nat.Commun. 10, 3312 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 374
  • 文献情報:
    Morimoto, D. et al. The unexpected role of polyubiquitin chains in the formation of fibrillar aggregates. Nat. Commun. 6, (2015).

  • 備考:
  • 参照:
    PubMed
  • No.: 375
  • 文献情報:
    Takahashi, S. et al. Loss of autophagy impairs physiological steatosis by accumulation of NCoR1. Life.Sci.Alliance. 3, (2020)

  • 備考:
  • 参照:
    PubMed
  • No.: 376
  • 文献情報:
    Sabino, C. et al. Bafilomycin A1 and U18666A Efficiently Impair ZIKV Infection. Viruses. 11, (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 377
  • 文献情報:
    Oliv辿, M. et al. Myoglobinopathy is an adult-onset autosomal dominant myopathy with characteristic sarcoplasmic inclusions. Nat.Commun. 10, 1396 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 378
  • 文献情報:
    Kageyama, S. et al. Proteasome Dysfunction Activates Autophagy and the Keap1-Nrf2 Pathway. J. Biol. Chem. 289, 24944–24955 (2014).

  • 備考:
  • 参照:
    PubMed
  • No.: 379
  • 文献情報:
    Venkatesh, A., Ma, S. & Punzo, C. TSC but not PTEN loss in starving cones of retinitis pigmentosa mice leads to an autophagy defect and mTORC1 dissociation from the lysosome. Cell Death Dis. 7, e2279窶兎2279 (2016).

  • 備考:
  • 参照:
    PubMed
  • No.: 380
  • 文献情報:
    Hoem, G. et al. The FMRpolyGlycine Protein Mediates Aggregate Formation and Toxicity Independent of the CGG mRNA Hairpin in a Cellular Model for FXTAS. Front.Genet. 10, 249 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 381
  • 文献情報:
    Ziegler, P. et al. Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis. Cell. 174, 88-101.e16 (2018)

  • 備考:
  • 参照:
    PubMed
  • No.: 382
  • 文献情報:
    Liu, S. et al. Lysosomal damage after spinal cord injury causes accumulation of RIPK1 and RIPK3 proteins and potentiation of necroptosis. Cell.Death.Dis. 9, 476 (2018).

  • 備考:
  • 参照:
    PubMed
  • No.: 383
  • 文献情報:
    Mildenberger, J. et al. N-3 PUFAs induce inflammatory tolerance by formation of KEAP1-containing SQSTM1/p62-bodies and activation of NFE2L2. Autophagy 00–00 (2017).

  • 備考:
  • 参照:
    PubMed
  • No.: 384
  • 文献情報:
    Barutcu, S. et al. Role of the MAPK/cJun NH2-terminal kinase signaling pathway in starvation-induced autophagy. Autophagy. 14, 1586-1595 (2018).

  • 備考:
  • 参照:
    PubMed
  • No.: 385
  • 文献情報:
    Khan, M. M. et al. Role of autophagy, SQSTM1, SH3GLB1, and TRIM63 in the turnover of nicotinic acetylcholine receptors. Autophagy 10, 123–36 (2014).

  • 備考:
  • 参照:
    PubMed
  • No.: 386
  • 文献情報:
    Mercer TJ et al. Phosphoproteomic identification of ULK substrates reveals VPS15-dependent ULK/VPS34 interplay in the regulation of autophagy. EMBO J 2021 Jul;40(14):e105985
    Mercer TJ et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 387
  • 文献情報:
    Prabakaran, T. et al. Attenuation of cGAS-STING signaling is mediated by a p62/SQSTM1-dependent autophagy pathway activated by TBK1. EMBO.J. 37, (2018)

  • 備考:
  • 参照:
    PubMed
  • No.: 388
  • 文献情報:
    Mejlvang, J. et al. Starvation induces rapid degradation of selective autophagy receptors by endosomal microautophagy. J.Cell.Biol. 217, 3640-3655 (2018)

  • 備考:
  • 参照:
    PubMed
  • No.: 389
  • 文献情報:
    Goodwin, J.M. et al. GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis. Sci Adv. 7, eabj2485(2021).

  • 備考:
  • 参照:
    PubMed
  • No.: 390
  • 文献情報:
    Tanaka, K. et al. A Novel Acylaminoimidazole Derivative, WN1316, Alleviates Disease Progression via Suppression of Glial Inflammation in ALS Mouse Model. PLoS One 9, (2014).

  • 備考:
  • 参照:
    PubMed
  • No.: 391
  • 文献情報:
    Mitsui, S. et al. Systemic overexpression of SQSTM1/p62 accelerates disease onset in a SOD1H46R-expressing ALS mouse model. Mol.Brain. 11, 30 (2018).

  • 備考:
  • 参照:
    PubMed
  • No.: 392
  • 文献情報:
    Todoric, J. et al. Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas. Cancer.Cell. 32, 824-839.e8 (2017)

  • 備考:
  • 参照:
    PubMed
  • No.: 393
  • 文献情報:
    Waguri, S. & Komatsu, M. Chapter 9 Biochemical and Morphological Detection of Inclusion Bodies in Autophagy-Deficient Mice. Methods in Enzymology 453, 181–196 (2009).

  • 備考:
  • 参照:
    PubMed
  • No.: 394
  • 文献情報:
    Sarraf, S. et al. PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis. Cell.Rep. 29, 225-235.e5 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 395
  • 文献情報:
    Zhang, J. et al. A Founder Mutation in VPS11 Causes an Autosomal Recessive Leukoencephalopathy Linked to Autophagic Defects. PLoS Genet. 12,(2016).

  • 備考:
  • 参照:
    PubMed
  • No.: 396
  • 文献情報:
    Fajardo, V. A. et al. Sarcolipin deletion exacerbates soleus muscle atrophy and weakness in phospholamban overexpressing mice. PLoS One 12, e0173708 (2017).

  • 備考:
  • 参照:
    PubMed
  • No.: 397
  • 文献情報:
    Taneike, M. et al. mTOR Hyperactivation by Ablation of Tuberous Sclerosis Complex 2 in the Mouse Heart Induces Cardiac Dysfunction with the Increased Number of Small Mitochondria Mediated through the Down-Regulation of Autophagy. PLoS One 11, (2016).

  • 備考:
  • 参照:
    PubMed
  • No.: 398
  • 文献情報:
    Dohmen, M. et al. AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy. Nat.Commun. 11, 1032 (2020)

  • 備考:
  • 参照:
    PubMed
  • No.: 399
  • 文献情報:
    Bl叩zquez C et al. Inhibition of striatonigral autophagy as a link between cannabinoid intoxication and impairment of motor coordination. Elife 2020 Aug;9
    Bl叩zquez C et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 400
  • 文献情報:
    Aghajan, M. et al. Antisense oligonucleotide treatment ameliorates IFN-粒-induced proteinuria in APOL1-transgenic mice. JCI.Insight. 4, (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 401
  • 文献情報:
    Ricketts, T. et al. A nonsense mutation in mouse Tardbp affects TDP43 alternative splicing activity and causes limb-clasping and body tone defects. PLoS One 9, (2014).

  • 備考:
  • 参照:
    PubMed
  • No.: 402
  • 文献情報:
    Felzen, V. et al. Estrogen receptor 留 regulates non-canonical autophagy that provides stress resistance to neuroblastoma and breast cancer cells and involves BAG3 function. Cell Death Dis. 6, (2015).

  • 備考:
  • 参照:
    PubMed
  • No.: 403
  • 文献情報:
    Lim, H. et al. A novel autophagy enhancer as a therapeutic agent against metabolic syndrome and diabetes. Nat.Commun. 9, 1438 (2018).

  • 備考:
  • 参照:
    PubMed
  • No.: 404
  • 文献情報:
    Li, Y. et al. cPLA2 activation contributes to lysosomal defects leading to impairment of autophagy after spinal cord injury. Cell.Death.Dis. 10, 531 (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 405
  • 文献情報:
    Jarvela, T. S. et al. The neural chaperone proSAAS blocks 留-synuclein fibrillation and neurotoxicity. Proc. Natl. Acad. Sci. U. S. A. (2016).

  • 備考:
  • 参照:
    PubMed
  • No.: 406
  • 文献情報:
    Kenific, C. M. et al. NBR1 enables autophagy-dependent focal adhesion turnover. J. Cell Biol. 212, 577–90 (2016).

  • 備考:
  • 参照:
    PubMed
  • No.: 407
  • 文献情報:
    Yamada, T. et al. Mitochondrial Stasis Reveals p62-Mediated Ubiquitination in Parkin-Independent Mitophagy and Mitigates Nonalcoholic Fatty Liver Disease. Cell.Metab. , (2018)

  • 備考:
  • 参照:
    PubMed
  • No.: 408
  • 文献情報:
    McMillan, E. M. et al. Autophagic signaling and proteolytic enzyme activity in cardiac and skeletal muscle of spontaneously hypertensive rats following chronic aerobic exercise. PLoS One 10, e0119382 (2015).

  • 備考:
  • 参照:
    PubMed
  • No.: 409
  • 文献情報:
    Rudnick JA et al. Autophagy in stromal fibroblasts promotes tumor desmoplasia and mammary tumorigenesis. Genes Dev 2021 Jul;35(13-14):963-975
    Rudnick JA et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 410
  • 文献情報:
    Suzuki, C. et al. Autophagy Deficiency in Renal Proximal Tubular Cells Leads to an Increase in Cellular Injury and Apoptosis under Normal Fed Conditions. Int.J.Mol.Sci. 21, (2019)

  • 備考:
  • 参照:
    PubMed
  • No.: 411
  • 文献情報:
    Zhang, L. et al. HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress. Nat. Commun. 5, (2014).

  • 備考:
  • 参照:
    PubMed
  • No.: 412
  • 文献情報:
    Kawakami, I. et al. Progression of phosphorylated 留-synuclein in Macaca fuscata. Brain Pathol. 31, e12952(2021).

  • 備考:
  • 参照:
    PubMed