Anti-53BP1, Rabbit-Poly

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• 商品コード：NB100-304SS
• メーカー：NOV
• 包装：0.025ml
• 価格： ¥55,000
• 在庫：無(未発注)

マイリストに追加 マイリストに追加済

• No.： 1
• 文献情報：
  Riballo E et al. A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci. Mol. Cell 2004 Dec;16(5):715-24
  Riballo E et al
  2004/01/01
  
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• No.： 2
• 文献情報：
  Lewinska A et al. Capsaicin-induced genotoxic stress does not promote apoptosis in A549 human lung and DU145 prostate cancer cells. Mutat Res Genet Toxicol Environ Mutagen 2015 Feb;779:23-34
  Lewinska A et al
  2015/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 3
• 文献情報：
  Carlessi L et al. Functional and molecular defects of hiPSC-derived neurons from patients with ATM deficiency. Cell Death Dis 2014;5:e1342
  Carlessi L et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 4
• 文献情報：
  Grabowska W et al. Curcumin induces senescence of primary human cells building the vasculature in a DNA damage and ATM-independent manner. Age (Dordr) 2015 Feb;37(1):9744
  Grabowska W et al
  2015/01/01
  
• 備考：
  Applications: ICC/IF
• 参照：
  

• No.： 5
• 文献情報：
  Naipal KA et al. Functional ex vivo assay to select homologous recombination-deficient breast tumors for PARP inhibitor treatment. Clin. Cancer Res. 2014 Sep;20(18):4816-26
  Naipal KA et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: IHC-P
• 参照：
  

• No.： 6
• 文献情報：
  Chene G et al. DNA Damage Signaling and Apoptosis in Preinvasive Tubal Lesions of Ovarian Carcinoma. Int. J. Gynecol. Cancer 2014 Jul;
  Chene G et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: IHC-P
• 参照：
  

• No.： 7
• 文献情報：
  Peng M et al. Crosstalk between BRCA-Fanconi anemia and mismatch repair pathways prevents MSH2-dependent aberrant DNA damage responses. EMBO J. 2014 Aug;33(15):1698-712
  Peng M et al
  2014/01/01
  
• 備考：
  Species: Human, Mouse, Applications: WB, ICC/IF
• 参照：
  

• No.： 8
• 文献情報：
  Baranski OA et al. Increased FOXM1 expression can stimulate DNA repair in normal hepatocytes in vivo but also increases nuclear foci associated with senescence. Cell Prolif. 2015 Feb;48(1):105-15
  Baranski OA et al
  2015/01/01
  
• 備考：
  Species: Mouse, Applications: IHC-Fr
• 参照：
  

• No.： 9
• 文献情報：
  Terasawa M et al. Canonical non-homologous end joining in mitosis induces genome instability and is suppressed by M-phase-specific phosphorylation of XRCC4. PLoS Genet. 2014 Aug;10(8):e1004563
  Terasawa M et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF, FLOW
• 参照：
  

• No.： 10
• 文献情報：
  Werner E et al. Opposite roles for p38MAPK-driven responses and reactive oxygen species in the persistence and resolution of radiation-induced genomic instability. PLoS ONE 2014;9(10):e108234
  Werner E et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 11
• 文献情報：
  Broering TJ et al. BRCA1 establishes DNA damage signaling and pericentric heterochromatin of the X chromosome in male meiosis. J. Cell Biol. 2014 Jun;205(5):663-75
  Broering TJ et al
  2014/01/01
  
• 備考：
  Species: Mouse, Applications: ICC/IF
• 参照：
  

• No.： 12
• 文献情報：
  Suram A et al. Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions. EMBO J. 2012;31(13):2839-51
  Suram A et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: IHC, ICC/IF
• 参照：
  

• No.： 13
• 文献情報：
  Neumayer G et al. TPX2 Impacts Acetylation of Histone H4 at Lysine 16: Implications for DNA Damage Response. PLoS ONE 2014;9(11):e110994
  Neumayer G et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: WB, ICC/IF
• 参照：
  

• No.： 14
• 文献情報：
  Gomes J et al. Pteridium aquilinum and its ptaquiloside toxin induce DNA damage response in gastric epithelial cells, a link with gastric carcinogenesis. Toxicol. Sci. 2012 Mar;126(1):60-71
  Gomes J et al
  2012/01/01
  
• 備考：
  Applications:
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• No.： 15
• 文献情報：
  Westin ER et al. The p53/p21(WAF/CIP) pathway mediates oxidative stress and senescence in dyskeratosis congenita cells with telomerase insufficiency. Antioxid. Redox Signal. 2011 Mar;14(6):985-97
  Westin ER et al
  2011/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 16
• 文献情報：
  Reichert S et al. Survivin inhibition and DNA double-strand break repair: a molecular mechanism to overcome radioresistance in glioblastoma. Radiother Oncol 2011 Oct;101(1):51-8
  Reichert S et al
  2011/01/01
  
• 備考：
  Species: Human, Applications: WB, ICC/IF
• 参照：
  

• No.： 17
• 文献情報：
  Le ON et al. Ionizing radiation-induced long-term expression of senescence markers in mice is independent of p53 and immune status. Aging Cell 2010 Jun;9(3):398-409
  Le ON et al
  2010/01/01
  
• 備考：
  Applications:
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• No.： 18
• 文献情報：
  Bolderson E et al. Kruppel-associated Box (KRAB)-associated co-repressor (KAP-1) Ser-473 phosphorylation regulates heterochromatin protein 1β (HP1-β) mobilization and DNA repair in heterochromatin. J. Biol. Chem. 2012 Aug;287(33):28122-31
  Bolderson E et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 19
• 文献情報：
  Kibe R et al. IL-7Rα deficiency in p53null mice exacerbates thymocyte telomere erosion and lymphomagenesis. Cell Death Differ. 2012 Jul;19(7):1139-51
  Kibe R et al
  2012/01/01
  
• 備考：
  Species: Mouse, Applications: ICC/IF
• 参照：
  

• No.： 20
• 文献情報：
  Luijsterburg MS et al. A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure. EMBO J. 2012 May;31(11):2511-27
  Luijsterburg MS et al
  2012/01/01
  
• 備考：
  Species: Mouse, Applications: ICC/IF
• 参照：
  

• No.： 21
• 文献情報：
  Tang M et al. Structural Maintenance of Chromosomes Flexible Hinge Domain Containing 1 (SMCHD1) Promotes Non-homologous End Joining and Inhibits Homologous Recombination Repair upon DNA Damage. J. Biol. Chem. 2014 Dec;289(49):34024-32
  Tang M et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: WB, ICC/IF
• 参照：
  

• No.： 22
• 文献情報：
  Remeseiro S et al. Reduction of Nipbl impairs cohesin loading locally and affects transcription but not cohesion-dependent functions in a mouse model of Cornelia de Lange Syndrome. Biochim. Biophys. Acta 2013 Dec;1832(12):2097-102
  Remeseiro S et al
  2013/01/01
  
• 備考：
  Species: Mouse, Applications: ICC-IF
• 参照：
  

• No.： 23
• 文献情報：
  B旦hringer M et al. siRNA screening identifies differences in the Fanconi anemia pathway in BALB/c-Trp53+/- with susceptibility versus C57BL/6-Trp53+/- mice with resistance to mammary tumors. Oncogene 2013 Feb;
  B旦hringer M et al
  2013/01/01
  
• 備考：
  Species: Mouse, Applications: ICC/IF
• 参照：
  

• No.： 24
• 文献情報：
  Francia S et al. Site-specific DICER and DROSHA RNA products control the DNA-damage response. Nature 2012 Aug;488(7410):231-5
  Francia S et al
  2012/01/01
  
• 備考：
  Species: Human, Mouse, Applications: ICC/IF
• 参照：
  

• No.： 25
• 文献情報：
  Dimitrova N et al. Cell cycle-dependent role of MRN at dysfunctional telomeres: ATM signaling-dependent induction of nonhomologous end joining (NHEJ) in G1 and resection-mediated inhibition of NHEJ in G2. Mol. Cell. Biol. 2009 Oct;29(20):5552-63
  Dimitrova N et al
  2009/01/01
  
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  Applications:
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• No.： 26
• 文献情報：
  Valero J et al. Pre-neurodegeneration of mitral cells in the pcd mutant mouse is associated with DNA damage, transcriptional repression, and reorganization of nuclear speckles and Cajal bodies. Mol. Cell. Neurosci. 2006 Nov;33(3):283-95
  Valero J et al
  2006/01/01
  
• 備考：
  Applications:
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• No.： 27
• 文献情報：
  Sato Y et al. Molecular basis of Lys-63-linked polyubiquitination inhibition by the interaction between human deubiquitinating enzyme OTUB1 and ubiquitin-conjugating enzyme UBC13. J. Biol. Chem. 2012 Jul;287(31):25860-8
  Sato Y et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 28
• 文献情報：
  Bielak-Zmijewska A et al. A comparison of replicative senescence and doxorubicin-induced premature senescence of vascular smooth muscle cells isolated from human aorta. Biogerontology 2014 Feb;15(1):47-64
  Bielak-Zmijewska A et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 29
• 文献情報：
  Elsen S et al. The opportunistic pathogen Pseudomonas aeruginosa activates the DNA double-strand break signaling and repair pathway in infected cells. Cell. Mol. Life Sci. 2013 Jun;
  Elsen S et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF, WB
• 参照：
  

• No.： 30
• 文献情報：
  Pont AR et al. mRNA Decay Factor AUF1 Maintains Normal Aging, Telomere Maintenance, and Suppression of Senescence by Activation of Telomerase Transcription. Mol. Cell 2012 Jul;47(1):5-15
  Pont AR et al
  2012/01/01
  
• 備考：
  Species: Mouse, Applications: ICC/IF
• 参照：
  

• No.： 31
• 文献情報：
  Burdak-Rothkamm S et al. BRCA1, FANCD2 and Chk1 are potential molecular targets for the modulation of a radiation-induced DNA damage response in bystander cells. Cancer Lett. 2015 Jan;356(2 Pt B):454-61
  Burdak-Rothkamm S et al
  2015/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 32
• 文献情報：
  Nishimaki N et al. Autocrine regulation of γ-irradiation-induced DNA damage response via extracellular nucleotides-mediated activation of P2Y6 and P2Y12 receptors. DNA Repair (Amst.) 2012 Aug;11(8):657-65
  Nishimaki N et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 33
• 文献情報：
  Mallette FA et al. RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites. EMBO J. 2012 Apr;31(8):1865-78
  Mallette FA et al
  2012/01/01
  
• 備考：
  Applications:
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• No.： 34
• 文献情報：
  Cortizas EM et al. Alternative end-joining and classical nonhomologous end-joining pathways repair different types of double-strand breaks during class-switch recombination. J. Immunol. 2013 Dec;191(11):5751-63
  Cortizas EM et al
  2013/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 35
• 文献情報：
  Zimmermann M et al. TRF1 negotiates TTAGGG repeat-associated replication problems by recruiting the BLM helicase and the TPP1/POT1 repressor of ATR signaling. Genes Dev. 2014 Nov;28(22):2477-91
  Zimmermann M et al
  2014/01/01
  
• 備考：
  Species: Mouse, Applications: WB, ICC/IF
• 参照：
  

• No.： 36
• 文献情報：
  Orsburn B et al. Differential requirement for H2AX and 53BP1 in organismal development and genome maintenance in the absence of poly(ADP)ribosyl polymerase 1. Mol. Cell. Biol. 2010 May;30(10):2341-52
  Orsburn B et al
  2010/01/01
  
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  Applications:
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• No.： 37
• 文献情報：
  Streppel MM et al. MicroRNA 223 is upregulated in the multistep progression of Barrett's esophagus and modulates sensitivity to chemotherapy by targeting PARP1. Clin. Cancer Res. 2013 Aug;19(15):4067-78
  Streppel MM et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 38
• 文献情報：
  Aarts M et al. Functional Genetic Screen Identifies Increased Sensitivity to WEE1 Inhibition in Cells with Defects in Fanconi Anemia and HR Pathways. Mol. Cancer Ther. 2015 Apr;14(4):865-76
  Aarts M et al
  2015/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 39
• 文献情報：
  Lewinska A et al. Curcumin induces oxidation-dependent cell cycle arrest mediated by SIRT7 inhibition of rDNA transcription in human aortic smooth muscle cells. Toxicol. Lett. 2015 Mar;233(3):227-38
  Lewinska A et al
  2015/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 40
• 文献情報：
  Chitnis MM et al. IGF-1R inhibition enhances radiosensitivity and delays double-strand break repair by both non-homologous end-joining and homologous recombination. Oncogene 2013 Nov;
  Chitnis MM et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 41
• 文献情報：
  Meng Y et al. Radiation-inducible immunotherapy for cancer: senescent tumor cells as a cancer vaccine. Mol. Ther. 2012 May;20(5):1046-55
  Meng Y et al
  2012/01/01
  
• 備考：
  Applications:
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• No.： 42
• 文献情報：
  Zahn A et al. Activation induced deaminase C-terminal domain links DNA breaks to end protection and repair during class switch recombination. Proc. Natl. Acad. Sci. U.S.A. 2014 Mar;111(11):E988-97
  Zahn A et al
  2014/01/01
  
• 備考：
  Species: Mouse, Applications: ChIP
• 参照：
  

• No.： 43
• 文献情報：
  Laschinsky L et al. Radiobiological effectiveness of laser accelerated electrons in comparison to electron beams from a conventional linear accelerator. J. Radiat. Res. 2012;53(3):395-403
  Laschinsky L et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 44
• 文献情報：
  Popuri V et al. RECQ1 is required for cellular resistance to replication stress and catalyzes strand exchange on stalled replication fork structures. Cell Cycle 2012 Nov;11(22):4252-65
  Popuri V et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 45
• 文献情報：
  Wei D et al. Inhibition of Protein Phosphatase 2A Radiosensitizes Pancreatic Cancers by Modulating CDC25C/CDK1 and Homologous Recombination Repair. Clin. Cancer Res. 2013 Aug;19(16):4422-32
  Wei D et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 46
• 文献情報：
  Scheers I et al. Human umbilical cord matrix stem cells maintain multilineage differentiation abilities and do not transform during long-term culture. PLoS ONE 2013;8(8):e71374
  Scheers I et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 47
• 文献情報：
  Ziebarth AJ et al. Endoglin (CD105) contributes to platinum resistance and is a target for tumor-specific therapy in epithelial ovarian cancer. Clin. Cancer Res. 2013 Jan;19(1):170-82
  Ziebarth AJ et al
  2013/01/01
  
• 備考：
  Species: Mouse, Applications: IHC, ICC/IF
• 参照：
  

• No.： 48
• 文献情報：
  Lovejoy CA et al. Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway. PLoS Genet 2012 Jul;8(7):e1002772
  Lovejoy CA et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 49
• 文献情報：
  Despars G et al. Loss of the osteogenic differentiation potential during senescence is limited to bone progenitor cells and is dependent on p53. PLoS ONE 2013;8(8):e73206
  Despars G et al
  2013/01/01
  
• 備考：
  Species: Mouse, Applications: ICC/IF
• 参照：
  

• No.： 50
• 文献情報：
  Eke I et al. Three-dimensional Invasion of Human Glioblastoma Cells Remains Unchanged by X-ray and Carbon Ion Irradiation In Vitro. Int. J. Radiat. Oncol. Biol. Phys. 2012 Aug;
  Eke I et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 51
• 文献情報：
  Mokrani-Benhelli H et al. Primary microcephaly, impaired DNA replication, and genomic instability caused by compound heterozygous ATR mutations. Hum. Mutat. 2013 Feb;34(2):374-84
  Mokrani-Benhelli H et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 52
• 文献情報：
  Moon SH et al. Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma-H2AX and suppresses DNA double strand break repair. J. Biol. Chem. 2010 Apr;285(17):12935-47
  Moon SH et al
  2010/01/01
  
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  Applications:
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• No.： 53
• 文献情報：
  Singh M et al. Matrix metalloproteinases and their inhibitors and inducer in gestational trophoblastic diseases and normal placenta. Gynecol. Oncol. 2011 Jul;122(1):178-82
  Singh M et al
  2011/01/01
  
• 備考：
  Species: Human, Applications: IHC-P
• 参照：
  

• No.： 54
• 文献情報：
  Viana-Pereira M et al. Microsatellite instability in pediatric high grade glioma is associated with genomic profile and differential target gene inactivation. PLoS ONE 2011;6(5):e20588
  Viana-Pereira M et al
  2011/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 55
• 文献情報：
  Grenier L et al. The activation of DNA damage detection and repair responses in cleavage-stage rat embryos by a damaged paternal genome. Toxicol. Sci. 2012 Jun;127(2):555-66
  Grenier L et al
  2012/01/01
  
• 備考：
  Species: Rat, Applications: ICC/IF
• 参照：
  

• No.： 56
• 文献情報：
  Korwek Z et al. DNA damage-independent apoptosis induced by curcumin in normal resting human T cells and leukaemic Jurkat cells. Mutagenesis 2013 Mar;
  Korwek Z et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 57
• 文献情報：
  Sotiropoulou PA et al. BRCA1 deficiency in skin epidermis leads to selective loss of hair follicle stem cells and their progeny. Genes Dev. 2013 Jan;27(1):39-51
  Sotiropoulou PA et al
  2013/01/01
  
• 備考：
  Species: Mouse, Applications: IHC, ICC/IF
• 参照：
  

• No.： 58
• 文献情報：
  Popova T et al. Ploidy and Large-Scale Genomic Instability Consistently Identify Basal-like Breast Carcinomas with BRCA1/2 Inactivation. Cancer Res. 2012 Nov;72(21):5454-62
  Popova T et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 59
• 文献情報：
  Leung JW et al. Nucleosome acidic patch promotes RNF168- and RING1B/BMI1-dependent H2AX and H2A ubiquitination and DNA damage signaling. PLoS Genet. 2014 Mar;10(3):e1004178
  Leung JW et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 60
• 文献情報：
  Korwek Z et al. Inhibition of ATM blocks the etoposide-induced DNA damage response and apoptosis of resting human T cells. DNA Repair (Amst.) 2012 Nov;11(11):864-73
  Korwek Z et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 61
• 文献情報：
  Vassilopoulos A et al. WEE1 murine deficiency induces hyper-activation of APC/C and results in genomic instability and carcinogenesis. Oncogene 2014 Aug;0
  Vassilopoulos A et al
  2014/01/01
  
• 備考：
  Species: Mouse, Applications: IHC-P
• 参照：
  

• No.： 62
• 文献情報：
  Taylor BJ et al. DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis. Elife 2013;2:e00534
  Taylor BJ et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 63
• 文献情報：
  Chan EA et al. Peripheral subnuclear positioning suppresses Tcrb recombination and segregates Tcrb alleles from RAG2. Proc. Natl. Acad. Sci. U.S.A. 2013 Nov;110(48):E4628-37
  Chan EA et al
  2013/01/01
  
• 備考：
  Species: Mouse, Applications: ICC/IF
• 参照：
  

• No.： 64
• 文献情報：
  Suberbielle E et al. Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β. Nat. Neurosci. 2013 May;16(5):613-21
  Suberbielle E et al
  2013/01/01
  
• 備考：
  Species: Mouse, Applications: ICC/IF
• 参照：
  

• No.： 65
• 文献情報：
  Hockemeyer D et al. Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres. Cell 2006 Jul;126(1):63-77
  Hockemeyer D et al
  2006/01/01
  
• 備考：
  Applications:
• 参照：
  

• No.： 66
• 文献情報：
  Ausborn NL et al. 53BP1 expression is a modifier of the prognostic value of lymph node ratio and CA 19-9 in pancreatic adenocarcinoma. BMC Cancer 2013;13:155
  Ausborn NL et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: IHC-P
• 参照：
  

• No.： 67
• 文献情報：
  Fernandez-L A et al. Oncogenic YAP promotes radioresistance and genomic instability in medulloblastoma through IGF2-mediated Akt activation. Oncogene 2012 Apr;31(15):1923-37
  Fernandez-L A et al
  2012/01/01
  
• 備考：
  Applications:
• 参照：
  

• No.： 68
• 文献情報：
  Li Z et al. Effect of radiation quality on mutagenic joining of enzymatically-induced DNA double-strand breaks in previously irradiated human cells. Radiat. Res. 2014 Nov;182(5):573-9
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