価格表
在庫・価格 ： 2025年08月04日 09時45分 現在
| 商品名 | 商品コード | メーカー | 包装 | 価格 | 在庫 | リスト |
|---|---|---|---|---|---|---|
|
Anti-HIF-1α, Mouse-Mono(H1α67) <Anti-Hypoxia-Inducible Factor 1α> データシート |
NB100-105 |
NOVノバス バイオロジカルス Novus biologicals, LLC |
0.1 ml | ¥108,000 | 1個 | 追加 |
在庫・価格 ： 2025年08月04日 09時45分 現在
使用文献
| No. | 文献情報 | 備考 | 参照 |
|---|---|---|---|
| 1 |
Sutter CH et al. Hypoxia-inducible factor 1alpha protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations. Proc. Natl. Acad. Sci. U.S.A. 2000 Apr;97(9):4748-53 Sutter CH et al 2000/01/01 |
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| 2 |
Kamura T et al. Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex. Proc. Natl. Acad. Sci. U.S.A. 2000 Sep;97(19):10430-5 Kamura T et al 2000/01/01 |
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| 3 |
Birner P et al. Overexpression of hypoxia-inducible factor 1alpha is a marker for an unfavorable prognosis in early-stage invasive cervical cancer. Cancer Res. 2000 Sep;60(17):4693-6 Birner P et al 2000/01/01 |
Species: Human, Applications: IHC-P | |
| 4 |
Ivan M et al. HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing. Science 2001 Apr;292(5516):464-8 Ivan M et al 2001/01/01 |
Immunoprecipitation | |
| 5 |
Birner P et al. Expression of hypoxia-inducible factor 1alpha in epithelial ovarian tumors: its impact on prognosis and on response to chemotherapy. Clin. Cancer Res. 2001 Jun;7(6):1661-8 Birner P et al 2001/01/01 |
Immunohistochemistry-paraffin, Human | |
| 6 |
Birner P et al. Expression of hypoxia-inducible factor-1 alpha in oligodendrogliomas: its impact on prognosis and on neoangiogenesis. Cancer 2001 Jul;92(1):165-71 Birner P et al 2001/01/01 |
Species: Human, Applications: IHC-P | |
| 7 |
Duyndam MC et al. Induction of vascular endothelial growth factor expression and hypoxia-inducible factor 1alpha protein by the oxidative stressor arsenite. J. Biol. Chem. 2001 Dec;276(51):48066-76 Duyndam MC et al 2001/01/01 |
Western blot, Human | |
| 8 |
Schindl M et al. Overexpression of hypoxia-inducible factor 1alpha is associated with an unfavorable prognosis in lymph node-positive breast cancer. Clin. Cancer Res. 2002 Jun;8(6):1831-7 Schindl M et al 2002/01/01 |
Immunohistochemistry-paraffin, Human | |
| 9 |
Powell JD et al. Stimulation of hypoxia-inducible factor-1 alpha (HIF-1alpha) protein in the adult rat testis following ischemic injury occurs without an increase in HIF-1alpha messenger RNA expression. Biol. Reprod. 2002 Sep;67(3):995-1002 Powell JD et al 2002/01/01 |
Species: Rat, Applications: WB | |
| 10 |
Ivan M et al. Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor. Proc. Natl. Acad. Sci. U.S.A. 2002 Oct;99(21):13459-64 Ivan M et al 2002/01/01 |
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| 11 |
Park JH et al. Gastric epithelial reactive oxygen species prevent normoxic degradation of hypoxia-inducible factor-1alpha in gastric cancer cells. Clin. Cancer Res. 2003 Jan;9(1):433-40 Park JH et al 2003/01/01 |
Species: Human, Applications: WB | |
| 12 |
Knies-Bamforth UE et al. c-Myc interacts with hypoxia to induce angiogenesis in vivo by a vascular endothelial growth factor-dependent mechanism. Cancer Res. 2004 Sep;64(18):6563-70 Knies-Bamforth UE et al 2004/01/01 |
Applications: WB | |
| 13 |
Aminova LR et al. Prosurvival and prodeath effects of hypoxia-inducible factor-1alpha stabilization in a murine hippocampal cell line. J. Biol. Chem. 2005 Feb;280(5):3996-4003 Aminova LR et al 2005/01/01 |
Species: Mouse, Applications: WB | |
| 14 |
Alberghini A et al. Loss of the von Hippel Lindau tumor suppressor disrupts iron homeostasis in renal carcinoma cells. J. Biol. Chem. 2005 Aug;280(34):30120-8 Alberghini A et al 2005/01/01 |
Species: Human, Applications: WB | |
| 15 |
Zagzag D et al. Stromal cell-derived factor-1alpha and CXCR4 expression in hemangioblastoma and clear cell-renal cell carcinoma: von Hippel-Lindau loss-of-function induces expression of a ligand and its receptor. Cancer Res. 2005 Jul;65(14):6178-88 Zagzag D et al 2005/01/01 |
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| 16 |
Liu W et al. Induction of tumor arrest and differentiation with prolonged survival by intermittent hypoxia in a mouse model of acute myeloid leukemia. Blood 2006 Jan;107(2):698-707 Liu W et al 2006/01/01 |
Species: Mouse, Applications: WB | |
| 17 |
Kong D et al. Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity. Cancer Res. 2005 Oct;65(19):9047-55 Kong D et al 2005/01/01 |
Species: Human, Applications: EMSA | |
| 18 |
Wang J et al. Cardiomyopathy associated with microcirculation dysfunction in laminin alpha4 chain-deficient mice. J. Biol. Chem. 2006 Jan;281(1):213-20 Wang J et al 2006/01/01 |
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| 19 |
Rodriguez-Porcel M et al. Functional and structural remodeling of the myocardial microvasculature in early experimental hypertension. Am. J. Physiol. Heart Circ. Physiol. 2006 Mar;290(3):H978-84 Rodriguez-Porcel M et al 2006/01/01 |
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| 20 |
Villanueva S et al. Ischemic acute renal failure induces the expression of a wide range of nephrogenic proteins. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2006 Apr;290(4):R861-70 Villanueva S et al 2006/01/01 |
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| 21 |
Quintero M et al. Nitric oxide is a factor in the stabilization of hypoxia-inducible factor-1alpha in cancer: role of free radical formation. Cancer Res. 2006 Jan;66(2):770-4 Quintero M et al 2006/01/01 |
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| 22 |
Higami Y et al. Energy restriction lowers the expression of genes linked to inflammation, the cytoskeleton, the extracellular matrix, and angiogenesis in mouse adipose tissue. J. Nutr. 2006 Feb;136(2):343-52 Higami Y et al 2006/01/01 |
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| 23 |
Galabova-Kovacs G et al. Essential role of B-Raf in ERK activation during extraembryonic development. Proc. Natl. Acad. Sci. U.S.A. 2006 Jan;103(5):1325-30 Galabova-Kovacs G et al 2006/01/01 |
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| 24 |
Trentin D et al. Peptide-matrix-mediated gene transfer of an oxygen-insensitive hypoxia-inducible factor-1alpha variant for local induction of angiogenesis. Proc. Natl. Acad. Sci. U.S.A. 2006 Feb;103(8):2506-11 Trentin D et al 2006/01/01 |
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| 25 |
Oda T et al. Activation of hypoxia-inducible factor 1 during macrophage differentiation. Am. J. Physiol., Cell Physiol. 2006 Jul;291(1):C104-13 Oda T et al 2006/01/01 |
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| 26 |
Hsu T et al. Endocytic function of von Hippel-Lindau tumor suppressor protein regulates surface localization of fibroblast growth factor receptor 1 and cell motility. J. Biol. Chem. 2006 Apr;281(17):12069-80 Hsu T et al 2006/01/01 |
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| 27 |
Luo Y et al. A constitutively active hypoxia-inducible factor-1alpha/VP16 hybrid factor activates expression of the human B-type natriuretic peptide gene. Mol. Pharmacol. 2006 Jun;69(6):1953-62 Luo Y et al 2006/01/01 |
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| 28 |
Hui AS et al. Calcium signaling stimulates translation of HIF-alpha during hypoxia. FASEB J. 2006 Mar;20(3):466-75 Hui AS et al 2006/01/01 |
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| 29 |
Lee KS et al. Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) reduces vascular endothelial growth factor expression in allergen-induced airway inflammation. Mol. Pharmacol. 2006 Jun;69(6):1829-39 Lee KS et al 2006/01/01 |
Species: Mouse, Applications: WB | |
| 30 |
Pore N et al. EGFR tyrosine kinase inhibitors decrease VEGF expression by both hypoxia-inducible factor (HIF)-1-independent and HIF-1-dependent mechanisms. Cancer Res. 2006 Mar;66(6):3197-204 Pore N et al 2006/01/01 |
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| 31 |
Fath DM et al. Histone deacetylase inhibitors repress the transactivation potential of hypoxia-inducible factors independently of direct acetylation of HIF-alpha. J. Biol. Chem. 2006 May;281(19):13612-9 Fath DM et al 2006/01/01 |
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| 32 |
Franco M et al. Targeted anti-vascular endothelial growth factor receptor-2 therapy leads to short-term and long-term impairment of vascular function and increase in tumor hypoxia. Cancer Res. 2006 Apr;66(7):3639-48 Franco M et al 2006/01/01 |
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| 33 |
Zampino M et al. Sex-related dimorphic response of HIF-1 alpha expression in myocardial ischemia. Am. J. Physiol. Heart Circ. Physiol. 2006 Aug;291(2):H957-64 Zampino M et al 2006/01/01 |
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| 34 |
Hu CJ et al. Differential regulation of the transcriptional activities of hypoxia-inducible factor 1 alpha (HIF-1alpha) and HIF-2alpha in stem cells. Mol. Cell. Biol. 2006 May;26(9):3514-26 Hu CJ et al 2006/01/01 |
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| 35 |
Wang R et al. Transcriptional regulation of APH-1A and increased gamma-secretase cleavage of APP and Notch by HIF-1 and hypoxia. FASEB J. 2006 Jun;20(8):1275-7 Wang R et al 2006/01/01 |
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| 36 |
Bracken CP et al. Cell-specific regulation of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha stabilization and transactivation in a graded oxygen environment. J. Biol. Chem. 2006 Aug;281(32):22575-85 Bracken CP et al 2006/01/01 |
Species: Human, Applications: WB | |
| 37 |
Bernhardt WM et al. Preconditional activation of hypoxia-inducible factors ameliorates ischemic acute renal failure. J. Am. Soc. Nephrol. 2006 Jul;17(7):1970-8 Bernhardt WM et al 2006/01/01 |
Species: Rat, Applications: IHC-P | |
| 38 |
Pacary E et al. Synergistic effects of CoCl(2) and ROCK inhibition on mesenchymal stem cell differentiation into neuron-like cells. J. Cell. Sci. 2006 Jul;119(Pt 13):2667-78 Pacary E et al 2006/01/01 |
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| 39 |
Chade AR et al. Simvastatin promotes angiogenesis and prevents microvascular remodeling in chronic renal ischemia. FASEB J. 2006 Aug;20(10):1706-8 Chade AR et al 2006/01/01 |
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| 40 |
Asikainen TM et al. Improved lung growth and function through hypoxia-inducible factor in primate chronic lung disease of prematurity. FASEB J. 2006 Aug;20(10):1698-700 Asikainen TM et al 2006/01/01 |
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| 41 |
McMahon S et al. Transforming growth factor beta1 induces hypoxia-inducible factor-1 stabilization through selective inhibition of PHD2 expression. J. Biol. Chem. 2006 Aug;281(34):24171-81 McMahon S et al 2006/01/01 |
Species: Human, Applications: WB | |
| 42 |
Villanueva S et al. bFGF induces an earlier expression of nephrogenic proteins after ischemic acute renal failure. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2006 Dec;291(6):R1677-87 Villanueva S et al 2006/01/01 |
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| 43 |
Brooks C et al. Characterization of cell clones isolated from hypoxia-selected renal proximal tubular cells. Am. J. Physiol. Renal Physiol. 2007 Jan;292(1):F243-52 Brooks C et al 2007/01/01 |
Species: Human, Applications: WB | |
| 44 |
Lin AD et al. Estrogen induces angiogenesis of the female rabbit bladder. J. Endocrinol. 2006 Aug;190(2):241-6 Lin AD et al 2006/01/01 |
Species: Rabbit, Applications: WB | |
| 45 |
Tanaka T et al. Hypoxia and expression of hypoxia-inducible factor in the aging kidney. J. Gerontol. A Biol. Sci. Med. Sci. 2006 Aug;61(8):795-805 Tanaka T et al 2006/01/01 |
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| 46 |
Hwang II et al. Loss of VHL confers hypoxia-inducible factor (HIF)-dependent resistance to vesicular stomatitis virus: role of HIF in antiviral response. J. Virol. 2006 Nov;80(21):10712-23 Hwang II et al 2006/01/01 |
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| 47 |
Shen F et al. Adeno-associated viral-vector-mediated hypoxia-inducible vascular endothelial growth factor gene expression attenuates ischemic brain injury after focal cerebral ischemia in mice. Stroke 2006 Oct;37(10):2601-6 Shen F et al 2006/01/01 |
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| 48 |
Carroll PA et al. Latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells activates hypoxia-induced factors. J. Virol. 2006 Nov;80(21):10802-12 Carroll PA et al 2006/01/01 |
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| 49 |
Chavez JC et al. The transcriptional activator hypoxia inducible factor 2 (HIF-2/EPAS-1) regulates the oxygen-dependent expression of erythropoietin in cortical astrocytes. J. Neurosci. 2006 Sep;26(37):9471-81 Chavez JC et al 2006/01/01 |
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| 50 |
McLaren AT et al. Increased expression of HIF-1alpha, nNOS, and VEGF in the cerebral cortex of anemic rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007 Jan;292(1):R403-14 McLaren AT et al 2007/01/01 |
Species: Rat, Applications: IHC-P, IF | |
| 51 |
Chen H et al. Hypoxic stress induces dimethylated histone H3 lysine 9 through histone methyltransferase G9a in mammalian cells. Cancer Res. 2006 Sep;66(18):9009-16 Chen H et al 2006/01/01 |
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| 52 |
Pore N et al. Nelfinavir down-regulates hypoxia-inducible factor 1alpha and VEGF expression and increases tumor oxygenation: implications for radiotherapy. Cancer Res. 2006 Sep;66(18):9252-9 Pore N et al 2006/01/01 |
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| 53 |
Khurana A et al. Regulation of the ring finger E3 ligase Siah2 by p38 MAPK. J. Biol. Chem. 2006 Nov;281(46):35316-26 Khurana A et al 2006/01/01 |
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| 54 |
Makino H et al. Altered gene expression related to glomerulogenesis and podocyte structure in early diabetic nephropathy of db/db mice and its restoration by pioglitazone. Diabetes 2006 Oct;55(10):2747-56 Makino H et al 2006/01/01 |
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| 55 |
Khan Z et al. Peroxisomal localization of hypoxia-inducible factors and hypoxia-inducible factor regulatory hydroxylases in primary rat hepatocytes exposed to hypoxia-reoxygenation. Am. J. Pathol. 2006 Oct;169(4):1251-69 Khan Z et al 2006/01/01 |
Species: Rat, Applications: IHC-P | |
| 56 |
Lukashev D et al. Cutting edge: hypoxia-inducible factor 1alpha and its activation-inducible short isoform I.1 negatively regulate functions of CD4+ and CD8+ T lymphocytes. J. Immunol. 2006 Oct;177(8):4962-5 Lukashev D et al 2006/01/01 |
Species: Mouse, Applications: WB | |
| 57 |
Biswas S et al. Insulin-induced activation of hypoxia-inducible factor-1 requires generation of reactive oxygen species by NADPH oxidase. Am. J. Physiol. Heart Circ. Physiol. 2007 Feb;292(2):H758-66 Biswas S et al 2007/01/01 |
Species: Human | |
| 58 |
Nemetski SM et al. Hypoxic regulation of Id-1 and activation of the unfolded protein response are aberrant in neuroblastoma. J. Biol. Chem. 2007 Jan;282(1):240-8 Nemetski SM et al 2007/01/01 |
Species: Mouse, Applications: WB | |
| 59 |
Veschini L et al. Hypoxia-inducible transcription factor-1 alpha determines sensitivity of endothelial cells to the proteosome inhibitor bortezomib. Blood 2007 Mar;109(6):2565-70 Veschini L et al 2007/01/01 |
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| 60 |
Nickols NG et al. Improved nuclear localization of DNA-binding polyamides. Nucleic Acids Res. 2007;35(2):363-70 Nickols NG et al 2007/01/01 |
Species: Human, Applications: ChIP | |
| 61 |
Kang SH et al. Antitumor effect of 2-methoxyestradiol in a rat orthotopic brain tumor model. Cancer Res. 2006 Dec;66(24):11991-7 Kang SH et al 2006/01/01 |
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| 62 |
Rosenberger C et al. Immunohistochemical detection of hypoxia-inducible factor-1alpha in human renal allograft biopsies. J. Am. Soc. Nephrol. 2007 Jan;18(1):343-51 Rosenberger C et al 2007/01/01 |
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| 63 |
Groenman F et al. Hypoxia-inducible factors in the first trimester human lung. J. Histochem. Cytochem. 2007 Apr;55(4):355-63 Groenman F et al 2007/01/01 |
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| 64 |
Liao H et al. Molecular regulation of the PAI-1 gene by hypoxia: contributions of Egr-1, HIF-1alpha, and C/EBPalpha. FASEB J. 2007 Mar;21(3):935-49 Liao H et al 2007/01/01 |
Species: Mouse | |
| 65 |
Winner M et al. Amplification of tumor hypoxic responses by macrophage migration inhibitory factor-dependent hypoxia-inducible factor stabilization. Cancer Res. 2007 Jan;67(1):186-93 Winner M et al 2007/01/01 |
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| 66 |
LaRusch GA et al. Nutlin3 blocks vascular endothelial growth factor induction by preventing the interaction between hypoxia inducible factor 1alpha and Hdm2. Cancer Res. 2007 Jan;67(2):450-4 LaRusch GA et al 2007/01/01 |
Species: Human, Applications: IP | |
| 67 |
Zhang X et al. Hypoxia-inducible factor 1alpha (HIF-1alpha)-mediated hypoxia increases BACE1 expression and beta-amyloid generation. J. Biol. Chem. 2007 Apr;282(15):10873-80 Zhang X et al 2007/01/01 |
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| 68 |
Bernhardt WM et al. Involvement of hypoxia-inducible transcription factors in polycystic kidney disease. Am. J. Pathol. 2007 Mar;170(3):830-42 Bernhardt WM et al 2007/01/01 |
Species: Rat, Applications: IHC-P | |
| 69 |
Ronkainen VP et al. Hypoxia inducible factor regulates the cardiac expression and secretion of apelin. FASEB J. 2007 Jun;21(8):1821-30 Ronkainen VP et al 2007/01/01 |
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| 70 |
Jayle C et al. Comparison of protective effects of trimetazidine against experimental warm ischemia of different durations: early and long-term effects in a pig kidney model. Am. J. Physiol. Renal Physiol. 2007 Mar;292(3):F1082-93 Jayle C et al 2007/01/01 |
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| 71 |
Kojima I et al. Protective role of hypoxia-inducible factor-2alpha against ischemic damage and oxidative stress in the kidney. J. Am. Soc. Nephrol. 2007 Apr;18(4):1218-26 Kojima I et al 2007/01/01 |
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| 72 |
Chin BY et al. Hypoxia-inducible factor 1alpha stabilization by carbon monoxide results in cytoprotective preconditioning. Proc. Natl. Acad. Sci. U.S.A. 2007 Mar;104(12):5109-14 Chin BY et al 2007/01/01 |
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| 73 |
Jeong CH et al. Hypoxia-inducible factor-1 alpha inhibits self-renewal of mouse embryonic stem cells in Vitro via negative regulation of the leukemia inhibitory factor-STAT3 pathway. J. Biol. Chem. 2007 May;282(18):13672-9 Jeong CH et al 2007/01/01 |
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| 74 |
Shimojo N et al. Contributory role of VEGF overexpression in endothelin-1-induced cardiomyocyte hypertrophy. Am. J. Physiol. Heart Circ. Physiol. 2007 Jul;293(1):H474-81 Shimojo N et al 2007/01/01 |
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| 75 |
Bateman RM et al. Myocardial hypoxia-inducible HIF-1alpha, VEGF, and GLUT1 gene expression is associated with microvascular and ICAM-1 heterogeneity during endotoxemia. Am. J. Physiol. Heart Circ. Physiol. 2007 Jul;293(1):H448-56 Bateman RM et al 2007/01/01 |
Species: Rat, Applications: WB | |
| 76 |
Zhang H et al. HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity. Cancer Cell 2007 May;11(5):407-20 Zhang H et al 2007/01/01 |
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| 77 |
Ide T et al. The hypoxic environment in tumor-stromal cells accelerates pancreatic cancer progression via the activation of paracrine hepatocyte growth factor/c-Met signaling. Ann. Surg. Oncol. 2007 Sep;14(9):2600-7 Ide T et al 2007/01/01 |
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| 78 |
Baek JH et al. Spermidine/spermine-N1-acetyltransferase 2 is an essential component of the ubiquitin ligase complex that regulates hypoxia-inducible factor 1alpha. J. Biol. Chem. 2007 Aug;282(32):23572-80 Baek JH et al 2007/01/01 |
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| 79 |
Lam W et al. The impact of hypoxic treatment on the expression of phosphoglycerate kinase and the cytotoxicity of troxacitabine and gemcitabine. Mol. Pharmacol. 2007 Sep;72(3):536-44 Lam W et al 2007/01/01 |
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| 80 |
Cheng G et al. Involvement of chloride channels in TGF-beta1-induced apoptosis of human bronchial epithelial cells. Am. J. Physiol. Lung Cell Mol. Physiol. 2007 Nov;293(5):L1339-47 Cheng G et al 2007/01/01 |
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| 81 |
Baek JH et al. Spermidine/spermine N(1)-acetyltransferase-1 binds to hypoxia-inducible factor-1alpha (HIF-1alpha) and RACK1 and promotes ubiquitination and degradation of HIF-1alpha. J. Biol. Chem. 2007 Nov;282(46):33358-66 Baek JH et al 2007/01/01 |
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| 82 |
Black SM et al. Regulation of fibroblast growth factor-2 expression in pulmonary arterial smooth muscle cells involves increased reactive oxygen species generation. Am. J. Physiol., Cell Physiol. 2008 Jan;294(1):C345-54 Black SM et al 2008/01/01 |
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| 83 |
Liu YV et al. Calcineurin promotes hypoxia-inducible factor 1alpha expression by dephosphorylating RACK1 and blocking RACK1 dimerization. J. Biol. Chem. 2007 Dec;282(51):37064-73 Liu YV et al 2007/01/01 |
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| 84 |
Engebretsen BJ et al. Acute hypobaric hypoxia (5486 m) induces greater pulmonary HIF-1 activation in hilltop compared to madison rats. High Alt. Med. Biol. 2007;8(4):312-21 Engebretsen BJ et al 2007/01/01 |
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| 85 |
Lomb DJ et al. Prolyl hydroxylase inhibitors depend on extracellular glucose and hypoxia-inducible factor (HIF)-2alpha to inhibit cell death caused by nerve growth factor (NGF) deprivation: evidence that HIF-2alpha has a role in NGF-promoted survival of s Lomb DJ et al 2009/01/01 |
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| 86 |
Alam H et al. Role of the phosphatidylinositol-3-kinase and extracellular regulated kinase pathways in the induction of hypoxia-inducible factor (HIF)-1 activity and the HIF-1 target vascular endothelial growth factor in ovarian granulosa cells in respons Alam H et al 2009/01/01 |
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| 87 |
Tanaka H et al. Iron facilitator LS081 reduces hypoxia-inducible factor-1α protein and functions as anticancer agent in hepatocellular carcinoma. Cancer Sci. 2012 Apr;103(4):767-74 Tanaka H et al 2012/01/01 |
Species: Human, Applications: WB | |
| 88 |
Milesi-Hall辿 A et al. Echinomycin decreases induction of vascular endothelial growth factor and hepatocyte regeneration in acetaminophen toxicity in mice. Basic Clin. Pharmacol. Toxicol. 2012 Apr;110(4):327-34 Milesi-Hall辿 A et al 2012/01/01 |
Species: Mouse, Applications: WB | |
| 89 |
Wang Y et al. Hypoxia promotes ligand-independent EGF receptor signaling via hypoxia-inducible factor-mediated upregulation of caveolin-1. Proc. Natl. Acad. Sci. U.S.A. 2012 Mar;109(13):4892-7 Wang Y et al 2012/01/01 |
Species: Human, Applications: EMSA, WB | |
| 90 |
Lin SK et al. Hypoxia-stimulated vascular endothelial growth factor production in human nasal polyp fibroblasts: effect of epigallocatechin-3-gallate on hypoxia-inducible factor-1 alpha synthesis. Arch. Otolaryngol. Head Neck Surg. 2008 May;134(5):522-7 Lin SK et al 2008/01/01 |
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| 91 |
Hughes D et al. Adventitial transplantation of blood outgrowth endothelial cells in porcine haemodialysis grafts alleviates hypoxia and decreases neointimal proliferation through a matrix metalloproteinase-9-mediated pathway--a pilot study. Nephrol. Dial. Hughes D et al 2009/01/01 |
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| 92 |
Tyagi A et al. Growth inhibition and regression of lung tumors by silibinin: modulation of angiogenesis by macrophage-associated cytokines and nuclear factor-kappaB and signal transducers and activators of transcription 3. Cancer Prev Res (Phila) 2009 Jan Tyagi A et al 2009/01/01 |
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| 93 |
Morine Y et al. Role of histone deacetylase expression in intrahepatic cholangiocarcinoma. Surgery 2012 Mar;151(3):412-9 Morine Y et al 2012/01/01 |
Species: Human, Applications: IHC | |
| 94 |
Wang B et al. Genistein inhibited retinal neovascularization and expression of vascular endothelial growth factor and hypoxia inducible factor 1alpha in a mouse model of oxygen-induced retinopathy. J Ocul Pharmacol Ther 2005 Apr;21(2):107-13 Wang B et al 2005/01/01 |
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| 95 |
Hsieh YL et al. Low-level laser therapy alleviates neuropathic pain and promotes function recovery in rats with chronic constriction injury: Possible involvements in hypoxia-inducible factor 1α (HIF-1α). J. Comp. Neurol. 2012 Sep;520(13):2903- Hsieh YL et al 2012/01/01 |
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| 96 |
Du F et al. Effects of hypoxic preconditioning on the expression of iron influx and efflux proteins in primary neuron culture. Neurochem. Int. 2012 Mar;60(4):335-43 Du F et al 2012/01/01 |
Species: Rat, Applications: WB | |
| 97 |
Bhaskar PT et al. mTORC1 hyperactivity inhibits serum deprivation-induced apoptosis via increased hexokinase II and GLUT1 expression, sustained Mcl-1 expression, and glycogen synthase kinase 3beta inhibition. Mol. Cell. Biol. 2009 Sep;29(18):5136-47 Bhaskar PT et al 2009/01/01 |
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| 98 |
Luo W et al. Hsp70 and CHIP selectively mediate ubiquitination and degradation of hypoxia-inducible factor (HIF)-1alpha but Not HIF-2alpha. J. Biol. Chem. 2010 Feb;285(6):3651-63 Luo W et al 2010/01/01 |
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| 99 |
Murphy BJ et al. Metallothionein induction by hypoxia involves cooperative interactions between metal-responsive transcription factor-1 and hypoxia-inducible transcription factor-1alpha. Mol. Cancer Res. 2008 Mar;6(3):483-90 Murphy BJ et al 2008/01/01 |
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| 100 |
Bohonowych JE et al. Comparative analysis of novel and conventional Hsp90 inhibitors on HIF activity and angiogenic potential in clear cell renal cell carcinoma: implications for clinical evaluation. BMC Cancer 2011;11:520 Bohonowych JE et al 2011/01/01 |
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| 101 |
Lang SA et al. Inhibition of heat shock protein 90 impairs epidermal growth factor-mediated signaling in gastric cancer cells and reduces tumor growth and vascularization in vivo. Mol. Cancer Ther. 2007 Mar;6(3):1123-32 Lang SA et al 2007/01/01 |
Species: Human, Applications: WB | |
| 102 |
Yang G et al. PTEN deficiency causes dyschondroplasia in mice by enhanced hypoxia-inducible factor 1alpha signaling and endoplasmic reticulum stress. Development 2008 Nov;135(21):3587-97 Yang G et al 2008/01/01 |
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| 103 |
Hsieh CH et al. Construction of mutant TKGFP for real-time imaging of temporal dynamics of HIF-1 signal transduction activity mediated by hypoxia and reoxygenation in tumors in living mice. J. Nucl. Med. 2009 Dec;50(12):2049-57 Hsieh CH et al 2009/01/01 |
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| 104 |
Cartee TV et al. Hypoxia and hypoxia mimetics inhibit TNF-dependent VCAM1 induction in the 5A32 endothelial cell line via a hypoxia inducible factor dependent mechanism. J. Dermatol. Sci. 2012 Feb;65(2):86-94 Cartee TV et al 2012/01/01 |
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Chen B et al. Rapamycin decreases survivin expression to induce NSCLC cell apoptosis under hypoxia through inhibiting HIF-1α induction. Mol. Biol. Rep. 2012 Jan;39(1):185-91 Chen B et al 2012/01/01 |
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Species: Human, Applications: IHC | |
| 220 |
Han MW et al. Role of FDG-PET as a biological marker for predicting the hypoxic status of tongue cancer. Head Neck 2011 Nov; Han MW et al 2011/01/01 |
Species: Human, Applications: IHC | |
| 221 |
Wilson GK et al. A dual role for hypoxia inducible factor-1α in the hepatitis C virus lifecycle and hepatoma migration. J. Hepatol. 2012 Apr;56(4):803-9 Wilson GK et al 2012/01/01 |
Species: Human, Applications: IHC, ICC, IF | |
| 222 |
Lim CS et al. Increased activation of the hypoxia-inducible factor pathway in varicose veins. J. Vasc. Surg. 2012 May;55(5):1427-39 Lim CS et al 2012/01/01 |
Species: Human, Applications: WB | |
| 223 |
Hayashi H et al. HIG1, a novel regulator of mitochondrial γ-secretase, maintains normal mitochondrial function. FASEB J. 2012 Jun;26(6):2306-17 Hayashi H et al 2012/01/01 |
Species: Human, Applications: WB | |
| 224 |
Natsuizaka M et al. Hypoxia induces IGFBP3 in esophageal squamous cancer cells through HIF-1α-mediated mRNA transcription and continuous protein synthesis. FASEB J. 2012 Jun;26(6):2620-30 Natsuizaka M et al 2012/01/01 |
Species: Human, Applications: ChIP | |
| 225 |
Jackson IL et al. Temporal expression of hypoxia-regulated genes is associated with early changes in redox status in irradiated lung. Free Radic. Biol. Med. 2012 Jul;53(2):337-46 Jackson IL et al 2012/01/01 |
Species: Mouse, Applications: WB | |
| 226 |
Lee JP et al. Soluble epoxide hydrolase activity determines the severity of ischemia-reperfusion injury in kidney. PLoS ONE 2012;7(5):e37075 Lee JP et al 2012/01/01 |
Species: Human, Applications: ICC, IF | |
| 227 |
Yang L et al. N-Acetylcysteine Protects Against Hypoxia Mimetic-Induced Autophagy by Targeting the HIF-1α Pathway in Retinal Ganglion Cells. Cell Mol Neurobiol 2012 May; Yang L et al 2012/01/01 |
Species: Rat, Applications: ICC, IF | |
| 228 |
Wang H et al. Impairment of osteoblast differentiation due to proliferation-independent telomere dysfunction in mouse models of accelerated aging. Aging Cell 2012 Aug;11(4):704-13 Wang H et al 2012/01/01 |
Species: Mouse, Applications: ICC, IF | |
| 229 |
Chintala S et al. Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibition. BMC Cancer 2012;12:293 Chintala S et al 2012/01/01 |
Species: Human, Applications: WB | |
| 230 |
Shim BY et al. Glucose transporter 1 (GLUT1) of anaerobic glycolysis as predictive and prognostic values in neoadjuvant chemoradiotherapy and laparoscopic surgery for locally advanced rectal cancer. Int J Colorectal Dis 2012 Jul; Shim BY et al 2012/01/01 |
Species: Human, Applications: IHC | |
| 231 |
Shafighi M et al. The role of androgens on hypoxia-inducible factor (HIF)-1α-induced angiogenesis and on the survival of ischemically challenged skin flaps in a rat model. Microsurgery 2012 Sep;32(6):475-81 Shafighi M et al 2012/01/01 |
Species: Human, Applications: WB | |
| 232 |
Chaudhuri S et al. Effect of trifluoperazine on toxicity, HIF-1α induction and hepatocyte regeneration in acetaminophen toxicity in mice. Toxicol. Appl. Pharmacol. 2012 Oct;264(2):192-201 Chaudhuri S et al 2012/01/01 |
Species: Mouse, Applications: WB | |
| 233 |
Sato K et al. Impaired response of hypoxic sensor protein HIF-1α and its downstream proteins in the spinal motor neurons of ALS model mice. Brain Res. 2012 Sep;1473:55-62 Sato K et al 2012/01/01 |
Species: Mouse, Applications: WB, IHC, ICC/IF | |
| 234 |
Sakamoto K et al. Differential modulation of surfactant protein D under acute and persistent hypoxia in acute lung injury. Am. J. Physiol. Lung Cell Mol. Physiol. 2012 Jul;303(1):L43-53 Sakamoto K et al 2012/01/01 |
Species: Human, Mouse, Applications: WB, IHC | |
| 235 |
Ke X et al. Hypoxia upregulates CD147 through a combined effect of HIF-1α and Sp1 to promote glycolysis and tumor progression in epithelial solid tumors. Carcinogenesis 2012 Aug;33(8):1598-607 Ke X et al 2012/01/01 |
Species: Human, Applications: ChIP | |
| 236 |
Singh AK et al. Intracellular pathogen Leishmania donovani activates hypoxia inducible factor-1 by dual mechanism for survival advantage within macrophage. PLoS ONE 2012;7(6):e38489 Singh AK et al 2012/01/01 |
Species: Mouse, Applications: WB | |
| 237 |
Tsukamoto S et al. Oxygen partial pressure modulates 67-kDa laminin receptor expression, leading to altered activity of the green tea polyphenol, EGCG. FEBS Lett. 2012 Sep;586(19):3441-7 Tsukamoto S et al 2012/01/01 |
Species: Mouse, Applications: WB | |
| 238 |
Koch Y et al. Connexin 31 (GJB3) deficiency in mouse trophoblast stem cells alters giant cell differentiation and leads to loss of oxygen sensing. Biol. Reprod. 2012 Aug;87(2):37 Koch Y et al 2012/01/01 |
Species: Mouse, Applications: WB | |
| 239 |
Chou CW et al. Tumor cycling hypoxia induces chemoresistance in glioblastoma multiforme by upregulating the expression and function of ABCB1. Neuro-oncology 2012 Oct;14(10):1227-38 Chou CW et al 2012/01/01 |
Species: Human, Applications: WB, IHC | |
| 240 |
Chiabrando D et al. Cell-specific regulation of Ferroportin transcription following experimentally-induced acute anemia in mice. Blood Cells Mol. Dis. 2012 Aug; Chiabrando D et al 2012/01/01 |
Species: Human, Applications: WB, IP | |
| 241 |
Baek JH et al. Induction of hypoxia inducible factor (HIF-1α) in rat kidneys by iron chelation with the hydroxypyridinone, CP94. Biochim. Biophys. Acta ;1809(4-6):262-8 Baek JH et al |
Species: Human, Applications: IP, WB | |
| 242 |
Pourvali K et al. Basal expression of copper transporter 1 in intestinal epithelial cells is regulated by hypoxia-inducible factor 2α. FEBS Lett. 2012 Jul;586(16):2423-7 Pourvali K et al 2012/01/01 |
Species: Human, Applications: WB | |
| 243 |
Tamaki Y et al. Angiotensin II type 1 receptor antagonist prevents hepatic carcinoma in rats with nonalcoholic steatohepatitis. J. Gastroenterol. 2012 Aug; Tamaki Y et al 2012/01/01 |
Species: Rat, Applications: IHC, WB | |
| 244 |
Hsieh CH et al. NADPH oxidase subunit 4 mediates cycling hypoxia-promoted radiation resistance in glioblastoma multiforme. Free Radic. Biol. Med. 2012 Aug;53(4):649-58 Hsieh CH et al 2012/01/01 |
Species: Mouse, Applications: IHC-Fr, IF | |
| 245 |
Boysen G et al. Identification and functional characterization of pVHL-dependent cell surface proteins in renal cell carcinoma. Neoplasia 2012 Jun;14(6):535-46 Boysen G et al 2012/01/01 |
Species: Human, Applications: ChIP | |
| 246 |
Nogami Y et al. Liposome-encapsulated hemoglobin attenuates cardiac dysfunction and sympathetic activity during hypohemoglobinemic shock. Shock 2012 Aug;38(2):159-64 Nogami Y et al 2012/01/01 |
Species: Rat, Applications: IHC | |
| 247 |
Jansen JF et al. Correlation of a priori DCE-MRI and (1)H-MRS data with molecular markers in neck nodal metastases: Initial analysis. Oral Oncol. 2012 Aug;48(8):717-22 Jansen JF et al 2012/01/01 |
Species: Human, Applications: IHC | |
| 248 |
Kim KJ et al. Melatonin suppresses tumor progression by reducing angiogenesis stimulated by HIF-1 in a mouse tumor model. J. Pineal Res. 2012 Jul; Kim KJ et al 2012/01/01 |
Species: Mouse, Applications: IHC | |
| 249 |
Krishnamachary B et al. Hypoxia Regulates CD44 and Its Variant Isoforms through HIF-1α in Triple Negative Breast Cancer. PLoS ONE 2012;7(8):e44078 Krishnamachary B et al 2012/01/01 |
Species: Human, Applications: WB | |
| 250 |
Broderick TL et al. Expression of cardiac GATA4 and downstream genes after exercise training in the db/db mouse. Pathophysiology 2012 Jun;19(3):193-203 Broderick TL et al 2012/01/01 |
Species: Mouse, Applications: WB | |
| 251 |
Zhang D et al. The Requirement of c-Jun N-terminal Kinase 2 in Regulation of Hypoxia-inducing Factor-1α mRNA Stability. J. Biol. Chem. 2012 Oct;287(41):34361-71 Zhang D et al 2012/01/01 |
Species: Mouse, Applications: WB | |
| 252 |
Takeda T et al. Hypoxia inducible factor-1α is necessary for invasive phenotype in Vegf-deleted islet cell tumors. Sci Rep 2012;2:494 Takeda T et al 2012/01/01 |
Species: Mouse, Applications: WB | |
| 253 |
Kaie K, Hideaki I, Chisato K, et al. Does Hypoxic Preconditioning Induce Angiogenesis and Protect against Focal Cerebral Ischemic Damage in Rats? . The Kitakanto medical journal. . 2011. |
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| 254 |
Giani JF et al. Angiotensin-(1-7) attenuates diabetic nephropathy in Zucker diabetic fatty rats. Am. J. Physiol. Renal Physiol. 2012 Jun;302(12):F1606-15 Giani JF et al 2012/01/01 |
Species: Rat, Applications: IHC, WB | |
| 255 |
Bai H et al. Hypoxia inducible factor-1α-mediated activation of survivin in cervical cancer cells. J. Obstet. Gynaecol. Res. 2012 Aug; Bai H et al 2012/01/01 |
Species: Human, Applications: IHC, WB | |
| 256 |
Kiss J et al. Loss of the oxygen sensor PHD3 enhances the innate immune response to abdominal sepsis. J. Immunol. 2012 Aug;189(4):1955-65 Kiss J et al 2012/01/01 |
Species: Mouse, Applications: WB | |
| 257 |
Li L et al. The importance of GLUT3 for de novo lipogenesis in hypoxia-induced lipid loading of human macrophages. PLoS ONE 2012;7(8):e42360 Li L et al 2012/01/01 |
Species: Human, Applications: IHC | |
| 258 |
Kondrashina, A A Phosphorescent Nanoparticle-Based Probe for Sensing and Imaging of (Intra)Cellular Oxygen in Multiple Detection Modalities Adv Funct Mater 2012 (ICC/IF, Rat) |
Species: Rat, Applications: ICC/IF | |
| 259 |
Bhawal UK et al. IL-1β-mediated up-regulation of DEC1 in human gingiva cells via the Akt pathway. J. Cell. Biochem. 2012 Oct;113(10):3246-53 Bhawal UK et al 2012/01/01 |
Species: Human, Applications: IHC | |
| 260 |
Kang YJ et al. Trichinella spiralis infection induces angiogenic factor thymosin β4 expression. Vet. Parasitol. 2011 Sep;181(2-4):222-8 Kang YJ et al 2011/01/01 |
Species: Mouse, Applications: IHC, WB | |
| 261 |
Veerman KJ. Investigating the Pro-Atherogenic Potential of Chronic Hyperglycemia: Is Diabetic Atherosclerosis a Microvascular Complication? [Internet]. 2011. |
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| 262 |
Spagnuolo RD. Role of HIF activation in the protection of cardiomyocytes from doxorubicin toxicity. 2011 Universita degli Studi di Milano. 2011. |
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| 263 |
Cal R et al. Low density lipoprotein receptor-related protein 1 expression correlates with cholesteryl ester accumulation in the myocardium of ischemic cardiomyopathy patients. J Transl Med 2012;10:160 Cal R et al 2012/01/01 |
Species: Human, Applications: IHC | |
| 264 |
Higashimura Y et al. Up-regulation of glyceraldehyde-3-phosphate dehydrogenase gene expression by HIF-1 activity depending on Sp1 in hypoxic breast cancer cells. Arch. Biochem. Biophys. 2011 May;509(1):1-8 Higashimura Y et al 2011/01/01 |
Species: Human, Applications: ChIP | |
| 265 |
Kitamoto S et al. Expression of MUC17 is regulated by HIF1α-mediated hypoxic responses and requires a methylation-free hypoxia responsible element in pancreatic cancer. PLoS ONE 2012;7(9):e44108 Kitamoto S et al 2012/01/01 |
Species: Human, Applications: WB | |
| 266 |
Sirvent A et al. Analysis of SRC oncogenic signaling in colorectal cancer by Stable Isotope Labeling with heavy Amino acids in mouse Xenografts. Mol. Cell Proteomics 2012 Sep; Sirvent A et al 2012/01/01 |
Species: Human, Applications: WB | |
| 267 |
Spagnuolo RD et al. Role of hypoxia-inducible factors in the dexrazoxane-mediated protection of cardiomyocytes from doxorubicin-induced toxicity. Br. J. Pharmacol. 2011 May;163(2):299-312 Spagnuolo RD et al 2011/01/01 |
Species: Rat, Applications: WB | |
| 268 |
Rider P et al. The transcription of the alarmin cytokine interleukin-1 alpha is controlled by hypoxia inducible factors 1 and 2 alpha in hypoxic cells. Front Immunol 2012;3:290 Rider P et al 2012/01/01 |
Species: Human, Applications: WB | |
| 269 |
Gautier-Stein A et al. Glucotoxicity Induces Glucose-6-Phosphatase Catalytic Unit Expression by Acting on the Interaction of HIF-1α With CREB-Binding Protein. Diabetes 2012 Oct;61(10):2451-60 Gautier-Stein A et al 2012/01/01 |
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| 270 |
Jensen R et al. Predicting outcomes of patients with intracranial meningiomas using molecular markers of hypoxia, vascularity, and proliferation. Neurosurgery 2012 Jul;71(1):146-56 Jensen R et al 2012/01/01 |
Species: Human, Applications: IHC | |
| 271 |
Sengupta T et al. Hypoxia-inducible factor 1 is activated by dysregulated cyclin E during mammary epithelial morphogenesis. Mol. Cell. Biol. 2011 Sep;31(18):3885-95 Sengupta T et al 2011/01/01 |
Species: Human, Applications: WB | |
| 272 |
Pore N et al. HIV protease inhibitors decrease VEGF/HIF-1alpha expression and angiogenesis in glioblastoma cells. Neoplasia 2006 Nov;8(11):889-95 Pore N et al 2006/01/01 |
Species: Human, Applications: WB | |
| 273 |
Pawlus MR et al. Upstream Stimulatory Factor 2 and Hypoxia-Inducible Factor 2α (HIF2α) Cooperatively Activate HIF2 Target Genes during Hypoxia. Mol. Cell. Biol. 2012 Nov;32(22):4595-610 Pawlus MR et al 2012/01/01 |
Species: Human, Applications: WB | |
| 274 |
Ciofani M et al. A validated regulatory network for th17 cell specification. Cell 2012 Oct;151(2):289-303 Ciofani M et al 2012/01/01 |
Species: Mouse, Applications: ChIP | |
| 275 |
Lee J et al. Ultraviolet A regulates the stemness of human adipose tissue-derived mesenchymal stem cells through downregulation of the HIF-1α via activation of PGE(2)-cAMP signaling. J. Cell. Biochem. 2012 Dec;113(12):3681-91 Lee J et al 2012/01/01 |
Species: Human, Applications: WB | |
| 276 |
Yamasaki T et al. Tumor microvasculature with endothelial fenestrations in VHL null clear cell renal cell carcinomas as a potent target of anti-angiogenic therapy. Cancer Sci. 2012 Nov;103(11):2027-37 Yamasaki T et al 2012/01/01 |
Species: Human, Applications: WB | |
| 277 |
Ortiz-Masià D et al. Induction of CD36 and Thrombospondin-1 in Macrophages by Hypoxia-Inducible Factor 1 and Its Relevance in the Inflammatory Process. PLoS ONE 2012;7(10):e48535 Ortiz-Masià D et al 2012/01/01 |
Species: Human, Applications: IP | |
| 278 |
Mahabeleshwar GH et al. A myeloid hypoxia-inducible factor 1α-Krüppel-like factor 2 pathway regulates gram-positive endotoxin-mediated sepsis. J. Biol. Chem. 2012 Jan;287(2):1448-57 Mahabeleshwar GH et al 2012/01/01 |
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| 279 |
Belibi F et al. Hypoxia-inducible factor-1α (HIF-1α) and autophagy in polycystic kidney disease (PKD). Am. J. Physiol. Renal Physiol. 2011 May;300(5):F1235-43 Belibi F et al 2011/01/01 |
Applications: IF | |
| 280 |
. ; |
Species: Human, Applications: WB | |
| 281 |
Zhu Q et al. Overexpression of HIF Prolyl-Hydoxylase-2 transgene in the renal medulla induced a salt sensitive hypertension. J. Cell. Mol. Med. 2012 Nov;16(11):2701-7 Zhu Q et al 2012/01/01 |
Species: Rat, Applications: WB | |
| 282 |
Zhou H et al. HIF-1α Inhibition Reduces Nasal Inflammation in a Murine Allergic Rhinitis Model. PLoS ONE 2012;7(11):e48618 Zhou H et al 2012/01/01 |
Species: Mouse, Applications: IHC, WB | |
| 283 |
Zhong H et al. Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases. Cancer Res. 1999 Nov;59(22):5830-5 Zhong H et al 1999/01/01 |
Species: Human, Mouse, Applications: IHC-P | |
| 284 |
Gothi辿 E et al. Identification of alternative spliced variants of human hypoxia-inducible factor-1alpha. J. Biol. Chem. 2000 Mar;275(10):6922-7 Gothi辿 E et al 2000/01/01 |
Species: Human, Applications: WB | |
| 285 |
Emerling BM et al. Identification of CDCP1 as a hypoxia-inducible factor 2α (HIF-2α) target gene that is associated with survival in clear cell renal cell carcinoma patients. Proc. Natl. Acad. Sci. U.S.A. 2013 Feb;110(9):3483-8 Emerling BM et al 2013/01/01 |
Species: Human, Applications: ChIP | |
| 286 |
Kakinuma Y et al. Heart-specific overexpression of choline acetyltransferase gene protects murine heart against ischemia through hypoxia-inducible factor-1α-related defense mechanisms. J Am Heart Assoc 2013;2(1):e004887 Kakinuma Y et al 2013/01/01 |
Species: Human, Mouse, Applications: WB | |
| 287 |
Kelleher AR et al. The mTORC1 signaling repressors REDD1/2 are rapidly induced and activation of p70S6K1 by leucine is defective in skeletal muscle of an immobilized rat hindlimb. Am. J. Physiol. Endocrinol. Metab. 2013 Jan;304(2):E229-36 Kelleher AR et al 2013/01/01 |
Species: Rat, Applications: WB | |
| 288 |
Nechemia-Arbely Y et al. In vivo evidence suggesting reciprocal renal hypoxia-inducible factor-1 upregulation and signal transducer and activator of transcription 3 activation in response to hypoxic and non-hypoxic stimuli. Clin. Exp. Pharmacol. Physiol. Nechemia-Arbely Y et al 2013/01/01 |
Species: Rat, Applications: IHC-P | |
| 289 |
Hsieh YL et al. Dry needling at myofascial trigger spots of rabbit skeletal muscles modulates the biochemicals associated with pain, inflammation, and hypoxia. Evid Based Complement Alternat Med 2012;2012:342165 Hsieh YL et al 2012/01/01 |
Species: Rabbit, Applications: WB | |
| 290 |
Vaughan MM et al. Double immunohistochemical staining method for HIF-1alpha and its regulators PHD2 and PHD3 in formalin-fixed paraffin-embedded tissues. Appl. Immunohistochem. Mol. Morphol. 2010 Jul;18(4):375-81 Vaughan MM et al 2010/01/01 |
Species: Human, Applications: IHC | |
| 291 |
Espinosa I et al. Myometrial invasion and lymph node metastasis in endometrioid carcinomas: tumor-associated macrophages, microvessel density, and HIF1A have a crucial role. Am. J. Surg. Pathol. 2010 Nov;34(11):1708-14 Espinosa I et al 2010/01/01 |
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| 292 |
Hebron ML et al. Parkin ubiquitinates Tar-DNA binding protein-43 (TDP-43) and promotes its cytosolic accumulation via interaction with histone deacetylase 6 (HDAC6). J. Biol. Chem. 2013 Feb;288(6):4103-15 Hebron ML et al 2013/01/01 |
Species: Mouse, Applications: WB | |
| 293 |
Zimmermann SM et al. Echinomycin in the prevention of heterotopic ossification - An experimental antibiotic agent shows promising results in a murine model. Injury 2013 Apr;44(4):570-5 Zimmermann SM et al 2013/01/01 |
Species: Mouse, Applications: IHC-P | |
| 294 |
Veerman KJ et al. Hyperglycaemia is associated with impaired vasa vasorum neovascularization and accelerated atherosclerosis in apolipoprotein-E deficient mice. Atherosclerosis 2013 Apr;227(2):250-8 Veerman KJ et al 2013/01/01 |
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| 295 |
Kawedia JD et al. Hypoxia and hypoxia mimetics decrease aquaporin 5 (AQP5) expression through both hypoxia inducible factor-1α and proteasome-mediated pathways. PLoS ONE 2013;8(3):e57541 Kawedia JD et al 2013/01/01 |
Species: Human, Applications: WB | |
| 296 |
Liang Y et al. Hypoxia-mediated sorafenib resistance can be overcome by EF24 through Von Hippel-Lindau tumor suppressor-dependent HIF-1α inhibition in hepatocellular carcinoma. Hepatology 2013 Jan; Liang Y et al 2013/01/01 |
Species: Human, Applications: ICC/IF | |
| 297 |
Luo W et al. Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression. Proc. Natl. Acad. Sci. U.S.A. 2012 Dec;109(49):E3367-76 Luo W et al 2012/01/01 |
Species: Human, Applications: ChIP | |
| 298 |
Ogane N et al. Clinicopathological implications of expressions of hypoxia-related molecules in esophageal superficial squamous cell carcinoma. Ann Diagn Pathol 2010 Feb;14(1):23-9 Ogane N et al 2010/01/01 |
Species: Human, Applications: IHC | |
| 299 |
Feliciano DM et al. Hypoxia-inducible factor 1a is a Tsc1-regulated survival factor in newborn neurons in tuberous sclerosis complex. Hum. Mol. Genet. 2013 May;22(9):1725-34 Feliciano DM et al 2013/01/01 |
Species: Human, Applications: WB | |
| 300 |
Chaturvedi P et al. Hypoxia-inducible factor-dependent breast cancer-mesenchymal stem cell bidirectional signaling promotes metastasis. J. Clin. Invest. 2013 Jan;123(1):189-205 Chaturvedi P et al 2013/01/01 |
Species: Human, Applications: WB | |
| 301 |
Roudier E et al. Murine double minute-2 expression is required for capillary maintenance and exercise-induced angiogenesis in skeletal muscle. FASEB J. 2012 Nov;26(11):4530-9 Roudier E et al 2012/01/01 |
Species: Rat, Applications: WB | |
| 302 |
Xue X et al. Hypoxia-inducible factor-2α activation promotes colorectal cancer progression by dysregulating iron homeostasis. Cancer Res. 2012 May;72(9):2285-93 Xue X et al 2012/01/01 |
Species: Mouse, Applications: WB | |
| 303 |
Crotty Alexander LE et al. Myeloid cell HIF-1α regulates asthma airway resistance and eosinophil function. J. Mol. Med. 2012 Dec; Crotty Alexander LE et al 2012/01/01 |
Species: Mouse, Applications: WB | |
| 304 |
Yoon J et al. Effects of oxygen tension and IGF-I on HIF-1α protein expression in mouse blastocysts. J. Assist. Reprod. Genet. 2013 Jan;30(1):99-105 Yoon J et al 2013/01/01 |
Species: Mouse, Applications: IHC, ICC/IF | |
| 305 |
Tanaka H et al. MicroRNA-183 upregulates HIF-1α by targeting isocitrate dehydrogenase 2 (IDH2) in glioma cells. J. Neurooncol. 2013 Feb;111(3):273-83 Tanaka H et al 2013/01/01 |
Species: Human, Applications: WB | |
| 306 |
Choy MK et al. PKB/Akt activation inhibits p53-mediated HIF1A degradation that is independent of MDM2. J. Cell. Physiol. 2010 Mar;222(3):635-9 Choy MK et al 2010/01/01 |
Species: Mouse, Rat, Applications: WB | |
| 307 |
Kimura Y et al. High-fat, high-sucrose, and high-cholesterol diets accelerate tumor growth and metastasis in tumor-bearing mice. Nutr Cancer 2007;59(2):207-16 Kimura Y et al 2007/01/01 |
Species: Mouse, Applications: WB, IHC | |
| 308 |
Kurt B et al. Deletion of von Hippel-Lindau protein converts renin-producing cells into erythropoietin-producing cells. J. Am. Soc. Nephrol. 2013 Feb;24(3):433-44 Kurt B et al 2013/01/01 |
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| 309 |
Towner RA et al. Regression of glioma tumor growth in F98 and U87 rat glioma models by the Nitrone OKN-007. Neuro-oncology 2013 Mar;15(3):330-40 Towner RA et al 2013/01/01 |
Species: Rat, Applications: IHC | |
| 310 |
Cicchillitti L et al. Hypoxia-inducible factor 1-α induces miR-210 in normoxic differentiating myoblasts. J. Biol. Chem. 2012 Dec;287(53):44761-71 Cicchillitti L et al 2012/01/01 |
Species: Mouse, Applications: WB | |
| 311 |
El Hasnaoui-Saadani R et al. Epo deficiency alters cardiac adaptation to chronic hypoxia. Respir Physiol Neurobiol 2013 Apr;186(2):146-54 El Hasnaoui-Saadani R et al 2013/01/01 |
Species: Mouse, Applications: IHC-P | |
| 312 |
Yoshida T et al. Digoxin inhibits retinal ischemia-induced HIF-1alpha expression and ocular neovascularization. FASEB J. 2010 Jun;24(6):1759-67 Yoshida T et al 2010/01/01 |
Species: Mouse, Applications: WB | |
| 313 |
Menon J et al. A novel interplay between Rap1 and PKA regulates induction of angiogenesis in prostate cancer. PLoS ONE 2012;7(11):e49893 Menon J et al 2012/01/01 |
Species: Human, Applications: WB | |
| 314 |
Grebhardt S et al. Hypoxia and HIF-1 increase S100A8 and S100A9 expression in prostate cancer. Int. J. Cancer 2012 Dec;131(12):2785-94 Grebhardt S et al 2012/01/01 |
Species: Human, Applications: WB | |
| 315 |
Heir P et al. DCNL1 Functions as a Substrate Sensor and Activator of Cullin 2-RING Ligase. Mol. Cell. Biol. 2013 Apr;33(8):1621-31 Heir P et al 2013/01/01 |
Species: Human, Applications: WB | |
| 316 |
Wu DC et al. Hypoxia regulates BMP4 expression in the murine spleen during the recovery from acute anemia. PLoS ONE 2010;5(6):e11303 Wu DC et al 2010/01/01 |
Species: Mouse, Applications: ChIP | |
| 317 |
Warren GW et al. Nicotinic modulation of therapeutic response in vitro and in vivo. Int. J. Cancer 2012 Dec;131(11):2519-27 Warren GW et al 2012/01/01 |
Species: Mouse, Applications: IHC | |
| 318 |
Lee JJ et al. Hypoxia activates the cyclooxygenase-2-prostaglandin E synthase axis. Carcinogenesis 2010 Mar;31(3):427-34 Lee JJ et al 2010/01/01 |
Species: Human, Applications: WB | |
| 319 |
Xie P et al. Suppression of experimental choroidal neovascularization by curcumin in mice. PLoS ONE 2012;7(12):e53329 Xie P et al 2012/01/01 |
Species: Mouse, Applications: WB | |
| 320 |
Nakamura J et al. HIF-1alpha is an unfavorable determinant of relapse in gastric cancer patients who underwent curative surgery followed by adjuvant 5-FU chemotherapy. Int. J. Cancer 2010 Sep;127(5):1158-71 Nakamura J et al 2010/01/01 |
Species: Human, Mouse, Applications: IHC | |
| 321 |
Nagara Y et al. Impaired Cytoplasmic-Nuclear Transport of Hypoxia-Inducible Factor-1α in Amyotrophic Lateral Sclerosis. Brain Pathol. 2013 Jan; Nagara Y et al 2013/01/01 |
Species: Mouse, Human, Applications: IHC-P, IHC-Fr, ICC/IF | |
| 322 |
Shizu R et al. Cross-talk between constitutive androstane receptor and hypoxia-inducible factor in the regulation of gene expression. Toxicol. Lett. 2013 May;219(2):143-50 Shizu R et al 2013/01/01 |
Species: Mouse, Applications: IP, ChIP, WB | |
| 323 |
Tamama K et al. Differential roles of hypoxia inducible factor subunits in multipotential stromal cells under hypoxic condition. J. Cell. Biochem. 2011 Mar;112(3):804-17 Tamama K et al 2011/01/01 |
Species: Human, Applications: WB, IHC | |
| 324 |
Sato Y et al. Cellular hypoxia of pancreatic beta-cells due to high levels of oxygen consumption for insulin secretion in vitro. J. Biol. Chem. 2011 Apr;286(14):12524-32 Sato Y et al 2011/01/01 |
Species: Mouse, Human, Applications: WB | |
| 325 |
Li C et al. Protective role of growth hormone against hyperhomocysteinemia-induced glomerular injury. Naunyn Schmiedebergs Arch. Pharmacol. 2013 Jun;386(6):551-61 Li C et al 2013/01/01 |
Species: Mouse, Applications: WB | |
| 326 |
Li L et al. HIF-1α Promotes A Hypoxia-Independent Cell Migration. Open Biol J 2010 Jan;3:8-14 Li L et al 2010/01/01 |
Species: Mouse, Applications: ICC/IF | |
| 327 |
Bendinelli P et al. Hypoxia inducible factor-1 is activated by transcriptional co-activator with PDZ-binding motif (TAZ) versus WWdomain-containing oxidoreductase (WWOX) in hypoxic microenvironment of bone metastasis from breast cancer. Eur. J. Cancer 201 Bendinelli P et al 2013/01/01 |
Species: Human, Applications: IHC | |
| 328 |
Hutter R et al. Macrophages Transmit Potent Proangiogenic Effects of oxLDL In Vitro and In Vivo Involving HIF-1α Activation: a Novel Aspect of Angiogenesis in Atherosclerosis. J Cardiovasc Transl Res 2013 Aug;6(4):558-69 Hutter R et al 2013/01/01 |
Species: Rabbit, Applications: IHC-P | |
| 329 |
. ; |
Species: Mouse, Applications: IHC-Fr, ICC/IF | |
| 330 |
Zhang H et al. Effect of advanced glycation end products on the expression of hypoxia-inducible factor-1α and vascular endothelial growth factor proteins in RF/6A cells. Exp Ther Med 2013 May;5(5):1519-1522 Zhang H et al 2013/01/01 |
Species: Primate, Applications: WB, ICC/IF | |
| 331 |
Park GC et al. Phospho-Rb (Ser780) as a biomarker in patients with cervical lymph node metastases from an unknown primary tumour: a retrospective cohort study. Clin Otolaryngol 2013 Aug;38(4):313-21 Park GC et al 2013/01/01 |
Species: Human, Applications: IHC-P | |
| 332 |
Bohuslavova R et al. Increased susceptibility of HIF-1α heterozygous-null mice to cardiovascular malformations associated with maternal diabetes. J. Mol. Cell. Cardiol. 2013 Jul;60:129-41 Bohuslavova R et al 2013/01/01 |
Species: Mouse, Applications: WB | |
| 333 |
Irwin DC et al. A potential role for reactive oxygen species and the HIF-1alpha-VEGF pathway in hypoxia-induced pulmonary vascular leak. Free Radic. Biol. Med. 2009 Jul;47(1):55-61 Irwin DC et al 2009/01/01 |
Species: Mouse, Applications: IHC-P | |
| 334 |
Park SJ et al. The histone demethylase JMJD1A regulates adrenomedullin-mediated cell proliferation in hepatocellular carcinoma under hypoxia. Biochem. Biophys. Res. Commun. 2013 Apr; Park SJ et al 2013/01/01 |
Species: Human, Applications: WB | |
| 335 |
Gauter-Fleckenstein B et al. Comparison of two Mn porphyrin-based mimics of superoxide dismutase in pulmonary radioprotection. Free Radic. Biol. Med. 2008 Mar;44(6):982-9 Gauter-Fleckenstein B et al 2008/01/01 |
Species: Rat, Applications: IHC-P | |
| 336 |
Kim HO et al. The C1772T genetic polymorphism in human HIF-1alpha gene associates with expression of HIF-1alpha protein in breast cancer. Oncol. Rep. 2008 Nov;20(5):1181-7 Kim HO et al 2008/01/01 |
Species: Human, Applications: IHC-P | |
| 337 |
Coudyzer P et al. Hypoxia is not required for human endometrial breakdown or repair in a xenograft model of menstruation. FASEB J. 2013 May; Coudyzer P et al 2013/01/01 |
Species: Human, Applications: IHC-P | |
| 338 |
Miyazawa M et al. Therapeutic strategy targeting the mTOR-HIF-1alpha-VEGF pathway in ovarian clear cell adenocarcinoma. Pathol. Int. 2009 Jan;59(1):19-27 Miyazawa M et al 2009/01/01 |
Species: Human, Applications: IHC | |
| 339 |
Loukovaara S et al. Elevated protein carbonyl and HIF-1α levels in eyes with proliferative diabetic retinopathy. Acta Ophthalmol 2013 May; Loukovaara S et al 2013/01/01 |
Applications: WB | |
| 340 |
Janardhanan R et al. Simvastatin reduces venous stenosis formation in a murine hemodialysis vascular access model. Kidney Int. 2013 Aug;84(2):338-52 Janardhanan R et al 2013/01/01 |
Species: Mouse, Applications: IHC-P | |
| 341 |
Borger DR et al. AMP-activated protein kinase is essential for survival in chronic hypoxia. Biochem. Biophys. Res. Commun. 2008 May;370(2):230-4 Borger DR et al 2008/01/01 |
Species: Human, Applications: WB | |
| 342 |
Kaie K, Hideaki I, Chisato K et al. Does Hypoxic Preconditioning Induce Angiogenesis and Protect against Focal Cerebral Ischemic Damage in Rats? . The Kitakanto medical journal. 2011 |
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| 343 |
Albers J et al. Combined mutation of Vhl and Trp53 causes renal cysts and tumours in mice. EMBO Mol Med 2013 Jun;5(6):949-64 Albers J et al 2013/01/01 |
Species: Mouse, Applications: WB, IHC-P | |
| 344 |
Kondrashina, A. A Phosphorescent Nanoparticle-Based Probe for Sensing and Imaging of (Intra)Cellular Oxygen in Multiple Detection Modalities Adv Funct Mater 2012 (ICC/IF, Rat) |
Species: Rat, Applications: ICC/IF | |
| 345 |
Nishimura R et al. Hypoxia is important for establishing vascularization during corpus luteum formation in cattle. J. Reprod. Dev. 2010 Feb;56(1):110-6 Nishimura R et al 2010/01/01 |
Species: Bovine, Applications: WB | |
| 346 |
Pawlus MR et al. STAT3 and HIF1α cooperatively activate HIF1 target genes in MDA-MB-231 and RCC4 cells. Oncogene 2013 Apr; Pawlus MR et al 2013/01/01 |
Species: Human, Applications: WB | |
| 347 |
Veerman KJ. Investigating the Pro-Atherogenic Potential of Chronic Hyperglycemia: Is Diabetic Atherosclerosis a Microvascular Complication? [Internet]. 2011 |
|
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| 348 |
Roh JL et al. The prognostic value of hypoxia markers in T2-staged oral tongue cancer. Oral Oncol. 2009 Jan;45(1):63-8 Roh JL et al 2009/01/01 |
Species: Human, Applications: IHC-P | |
| 349 |
Musyoka JN et al. Siah2-deficient mice show impaired skin wound repair. Wound Repair Regen ;21(3):437-47 Musyoka JN et al |
Species: Mouse, Applications: IHC-P | |
| 350 |
Spagnuolo RD. Role of HIF activation in the protection of cardiomyocytes from doxorubicin toxicity. 2011 Universita degli Studi di Milano. 2011 |
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| 351 |
Wang W et al. Loss of Apelin Exacerbates Myocardial Infarction Adverse Remodeling and Ischemia-reperfusion Injury: Therapeutic Potential of Synthetic Apelin Analogues. J Am Heart Assoc 2013;2(4):e000249 Wang W et al 2013/01/01 |
Species: Mouse, Applications: IHC-P, ICC/IF, WB | |
| 352 |
Kim YJ et al. Overcoming evasive resistance from vascular endothelial growth factor a inhibition in sarcomas by genetic or pharmacologic targeting of hypoxia-inducible factor 1α. Int. J. Cancer 2013 Jan;132(1):29-41 Kim YJ et al 2013/01/01 |
Species: Human, Applications: IHC-P | |
| 353 |
Shimomura M et al. Overexpression of Hypoxia Inducible Factor-1 Alpha is an Independent Risk Factor for Recurrence After Curative Resection of Colorectal Liver Metastases. Ann. Surg. Oncol. 2013 Jun; Shimomura M et al 2013/01/01 |
Species: Human, Applications: IHC-P | |
| 354 |
Wu C et al. Delivery of dimethyloxallyl glycine in mesoporous bioactive glass scaffolds to improve angiogenesis and osteogenesis of human bone marrow stromal cells. Acta Biomater 2013 Jun; Wu C et al 2013/01/01 |
Species: Human, Applications: WB | |
| 355 |
Sun YY et al. Cell type-specific dependency on the PI3K/Akt signaling pathway for the endogenous Epo and VEGF induction by baicalein in neurons versus astrocytes. PLoS ONE 2013;8(7):e69019 Sun YY et al 2013/01/01 |
Species: Rat, Applications: ChIP | |
| 356 |
Xu H et al. Correlation between 18F-FDG uptake and the expression of glucose transporter-1 and hypoxia-inducible factor-1α in transplanted VX2 tumors. Nucl Med Commun 2013 Oct;34(10):953-8 Xu H et al 2013/01/01 |
Species: Rabbit, Applications: IHC-P | |
| 357 |
Xie L et al. Transcription Factors Sp1 and Hif2α Mediate Induction of the Copper-transporting ATPase (Atp7a) Gene in Intestinal Epithelial Cells during Hypoxia. J. Biol. Chem. 2013 Aug;288(33):23943-52 Xie L et al 2013/01/01 |
Species: Rat, Applications: WB | |
| 358 |
Stokes DG et al. Assessment of the gene expression profile of differentiated and dedifferentiated human fetal chondrocytes by microarray analysis. Arthritis Rheum. 2002 Feb;46(2):404-19 Stokes DG et al 2002/01/01 |
Species: Bovine, Applications: WB | |
| 359 |
Shin JM et al. Melittin Suppresses HIF-1α/VEGF Expression through Inhibition of ERK and mTOR/p70S6K Pathway in Human Cervical Carcinoma Cells. PLoS ONE 2013;8(7):e69380 Shin JM et al 2013/01/01 |
Species: Human, Applications: ChIP | |
| 360 |
Belloli S et al. Characterization of biological features of a rat F98 GBM model: A PET-MRI study with [(18)F]FAZA and [(18)F]FDG. Nucl. Med. Biol. 2013 Aug;40(6):831-40 Belloli S et al 2013/01/01 |
Species: Rat, Applications: IHC-P | |
| 361 |
Kondrashina AV et al. Measurement of cell respiration and oxygenation in standard multichannel biochips using phosphorescent O2-sensitive probes. Analyst 2013 Sep;138(17):4915-21 Kondrashina AV et al 2013/01/01 |
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| 362 |
Ma Z et al. Preconditioning with Associated Blocking of Ca(2+) Inflow Alleviates Hypoxia-Induced Damage to Pancreatic β-Cells. PLoS ONE 2013;8(7):e67498 Ma Z et al 2013/01/01 |
Species: Rat, Applications: WB | |
| 363 |
Takikawa T et al. miR-210 regulates the interaction between pancreatic cancer cells and stellate cells. Biochem. Biophys. Res. Commun. 2013 Aug;437(3):433-9 Takikawa T et al 2013/01/01 |
Species: Human, Applications: ICC/IF | |
| 364 |
Al-Greene NT et al. Four jointed box 1 promotes angiogenesis and is associated with poor patient survival in colorectal carcinoma. PLoS ONE 2013;8(7):e69660 Al-Greene NT et al 2013/01/01 |
Species: Human, Applications: WB | |
| 365 |
Namas RA et al. Hypoxia-induced overexpression of BNIP3 is not dependent on hypoxia-inducible factor 1α in mouse hepatocytes. Shock 2011 Aug;36(2):196-202 Namas RA et al 2011/01/01 |
Species: Mouse, Applications: WB | |
| 366 |
Thangarajah H et al. IFATS collection: Adipose stromal cells adopt a proangiogenic phenotype under the influence of hypoxia. Stem Cells 2009 Jan;27(1):266-74 Thangarajah H et al 2009/01/01 |
Species: Mouse, Applications: WB | |
| 367 |
Jung JH et al. Clinicopathological implications of the expression of hypoxia-related proteins in gastric cancer. Int J Med Sci 2013;10(9):1217-23 Jung JH et al 2013/01/01 |
Species: Human, Applications: IHC-P | |
| 368 |
Allon I et al. HIF-1α, VEGF, and EGFR: contributing factors in the pathogenesis of necrotizing sialometaplasia. Oral Dis 2013 Jun; Allon I et al 2013/01/01 |
Species: Human, Applications: IHC-P | |
| 369 |
Park YK et al. Hypoxia-inducible Factor-2α-dependent Hypoxic Induction of Wnt10b Expression in Adipogenic Cells. J. Biol. Chem. 2013 Sep;288(36):26311-22 Park YK et al 2013/01/01 |
Species: Mouse, Applications: WB | |
| 370 |
Sundelin JP et al. Hypoxia-induced regulation of the very low density lipoprotein receptor. Biochem. Biophys. Res. Commun. 2013 Jul;437(2):274-9 Sundelin JP et al 2013/01/01 |
Species: Mouse, Applications: ChIP | |
| 371 |
You Q et al. Role of hepatic resident and infiltrating macrophages in liver repair after acute injury. Biochem. Pharmacol. 2013 Sep;86(6):836-43 You Q et al 2013/01/01 |
Species: Mouse, Applications: WB | |
| 372 |
Thomas R et al. A HIF-1alpha-dependent autocrine feedback loop promotes survival of serum-deprived prostate cancer cells. Prostate 2009 Feb;69(3):263-75 Thomas R et al 2009/01/01 |
Species: Human, Applications: WB | |
| 373 |
Kurebayashi J et al. Hypoxia reduces hormone responsiveness of human breast cancer cells. Jpn. J. Cancer Res. 2001 Oct;92(10):1093-101 Kurebayashi J et al 2001/01/01 |
Species: Human, Applications: IHC-P | |
| 374 |
Sato Y et al. Integrated molecular analysis of clear-cell renal cell carcinoma. Nat. Genet. 2013 Aug;45(8):860-7 Sato Y et al 2013/01/01 |
Species: Human, Applications: IHC | |
| 375 |
Tezel G et al. Hypoxia-inducible factor 1alpha in the glaucomatous retina and optic nerve head. Arch. Ophthalmol. 2004 Sep;122(9):1348-56 Tezel G et al 2004/01/01 |
Species: Human, Applications: IHC-P | |
| 376 |
Erler JT et al. Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance. Mol. Cell. Biol. 2004 Apr;24(7):2875-89 Erler JT et al 2004/01/01 |
Species: Mouse, Human, Applications: WB | |
| 377 |
Wall AM et al. Effects of prolyl-hydroxylase inhibition and chronic intermittent hypoxia on synaptic transmission and plasticity in the rat CA1 and dentate gyrus. Neurobiol. Dis. 2014 Feb;62:8-17 Wall AM et al 2014/01/01 |
Species: Rat, Applications: WB | |
| 378 |
Tan JT et al. High-density lipoproteins augment hypoxia-induced angiogenesis via regulation of post-translational modulation of hypoxia-inducible factor 1α. FASEB J. 2014 Jan;28(1):206-17 Tan JT et al 2014/01/01 |
Species: Human, Applications: WB | |
| 379 |
Minoia C et al. Changes in angiogenesis and hypoxia-inducible factor-1α protein expression in relapsed/refractory indolent non-Hodgkin lymphomas. Br. J. Haematol. 2013 Dec;163(5):640-5 Minoia C et al 2013/01/01 |
Species: Human, Applications: IHC | |
| 380 |
Miyauchi Y et al. HIF1α is required for osteoclast activation by estrogen deficiency in postmenopausal osteoporosis. Proc. Natl. Acad. Sci. U.S.A. 2013 Oct;110(41):16568-73 Miyauchi Y et al 2013/01/01 |
Species: Mouse, Applications: WB, IHC-P, ICC/IF | |
| 381 |
Hu P et al. Convergent RANK- and c-Met-mediated signaling components predict survival of patients with prostate cancer: an interracial comparative study. PLoS ONE 2013;8(9):e73081 Hu P et al 2013/01/01 |
Species: Human | |
| 382 |
Zhang L et al. The presence of adenosine A2a receptor in thyrocytes and its involvement in Graves' IgG-induced VEGF expression. Endocrinology 2013 Dec;154(12):4927-38 Zhang L et al 2013/01/01 |
Species: Mouse, Human, Applications: WB, IHC-P, ICC/IF | |
| 383 |
Ding G et al. MiR-199a suppresses the hypoxia-induced proliferation of non-small cell lung cancer cells through targeting HIF1α. Mol. Cell. Biochem. 2013 Dec;384(1-2):173-80 Ding G et al 2013/01/01 |
Species: Human, Applications: WB, IHC | |
| 384 |
Gallaher AM et al. Proteomic screening of human targets of viral microRNAs reveals functions associated with immune evasion and angiogenesis. PLoS Pathog. 2013;9(9):e1003584 Gallaher AM et al 2013/01/01 |
Species: Human, Applications: WB | |
| 385 |
Wang SC et al. Radiation therapy-induced tumor invasiveness is associated with SDF-1-regulated macrophage mobilization and vasculogenesis. PLoS ONE 2013;8(8):e69182 Wang SC et al 2013/01/01 |
Species: Mouse, Applications: WB | |
| 386 |
Eckle T et al. HIF1A reduces acute lung injury by optimizing carbohydrate metabolism in the alveolar epithelium. PLoS Biol. 2013 Sep;11(9):e1001665 Eckle T et al 2013/01/01 |
Species: Human, Mouse, Applications: WB, IHC-P | |
| 387 |
Lin WP et al. Polymorphism in the hypoxia-inducible factor 1alpha gene may confer susceptibility to LDD in Chinese cohort. PLoS ONE 2013;8(8):e73158 Lin WP et al 2013/01/01 |
Species: Human, Applications: WB | |
| 388 |
Hu CJ et al. The N-terminal transactivation domain confers target gene specificity of hypoxia-inducible factors HIF-1alpha and HIF-2alpha. Mol. Biol. Cell 2007 Nov;18(11):4528-42 Hu CJ et al 2007/01/01 |
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| 389 |
Zaccagnini G et al. Hypoxia-Induced miR-210 Modulates Tissue Response to Acute Peripheral Ischemia. Antioxid. Redox Signal. 2013 Oct; Zaccagnini G et al 2013/01/01 |
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| 390 |
Takibuchi G et al. Polymorphic mutations in mouse mitochondrial DNA regulate a tumor phenotype. Mitochondrion 2013 Nov;13(6):881-7 Takibuchi G et al 2013/01/01 |
Species: Mouse, Applications: WB | |
| 391 |
Cowburn AS et al. Epidermal Deletion of HIF-2α Stimulates Wound Closure. J. Invest. Dermatol. 2013 Sep; Cowburn AS et al 2013/01/01 |
Species: Mouse, Applications: IHC-P | |
| 392 |
Cao Y et al. Tumor cells upregulate normoxic HIF-1α in response to doxorubicin. Cancer Res. 2013 Oct;73(20):6230-42 Cao Y et al 2013/01/01 |
Species: Human, Mouse, Applications: WB | |
| 393 |
Dimova EY et al. Hypoxia-inducible factors: post-translational crosstalk of signaling pathways. Methods Mol. Biol. 2010;647:215-36 Dimova EY et al 2010/01/01 |
Species: Human, Applications: WB | |
| 394 |
Pawlus MR et al. STAT3 or USF2 contributes to HIF target gene specificity. PLoS ONE 2013;8(8):e72358 Pawlus MR et al 2013/01/01 |
Species: Human, Applications: ChIP | |
| 395 |
An X et al. Expression of hypoxia-inducible factor-1α, vascular endothelial growth factor and prolyl hydroxylase domain protein 2 in cutaneous squamous cell carcinoma and precursor lesions and their relationship with histological stages and clinical An X et al 2014/01/01 |
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| 396 |
Jensen RL et al. Preoperative dynamic contrast-enhanced MRI correlates with molecular markers of hypoxia and vascularity in specific areas of intratumoral microenvironment and is predictive of patient outcome. Neuro-oncology 2014 Jan;16(2):280-91 Jensen RL et al 2014/01/01 |
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| 397 |
Engelhardt S et al. Hypoxia Selectively Disrupts Brain Microvascular Endothelial Tight Junction Complexes Through A Hypoxia-Inducible Factor-1 (HIF-1) Dependent Mechanism. J. Cell. Physiol. 2013 Dec; Engelhardt S et al 2013/01/01 |
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| 398 |
Miyazaki S et al. Anti-VEGF antibody therapy induces tumor hypoxia and stanniocalcin 2 expression and potentiates growth of human colon cancer xenografts. Int. J. Cancer 2013 Dec; Miyazaki S et al 2013/01/01 |
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| 399 |
Watson CJ et al. Hypoxia-induced epigenetic modifications are associated with cardiac tissue fibrosis and the development of a myofibroblast-like phenotype. Hum. Mol. Genet. 2013 Dec; Watson CJ et al 2013/01/01 |
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| 400 |
Park HJ et al. Hypoxia Regulates the Expression of the Neuromedin B Receptor through a Mechanism Dependent on Hypoxia-Inducible Factor-1α. PLoS ONE 2013;8(12):e82868 Park HJ et al 2013/01/01 |
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| 401 |
Koide N et al. Augmentation of LPS-induced vascular endothelial cell growth factor production in macrophages by transforming growth factor-β1. Innate Immun 2013 Nov; Koide N et al 2013/01/01 |
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| 402 |
Madej JA et al. Expression of hypoxia-inducible factor-1α and vascular density in mammary adenomas and adenocarcinomas in bitches. Acta Vet. Scand. 2013;55(1):73 Madej JA et al 2013/01/01 |
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| 403 |
Ouyang W et al. Anthrax Lethal Toxin Inhibits Translation of Hypoxia-inducible Factor 1α and Causes Decreased Tolerance to Hypoxic Stress. J. Biol. Chem. 2014 Feb;289(7):4180-90 Ouyang W et al 2014/01/01 |
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| 404 |
Ma Z et al. Hyperoxia inhibits glucose-induced insulin secretion and mitochondrial metabolism in rat pancreatic islets. Biochem. Biophys. Res. Commun. 2014 Jan;443(1):223-8 Ma Z et al 2014/01/01 |
|
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| 405 |
Zhang C et al. Berberine radiosensitizes human nasopharyngeal carcinoma by suppressing hypoxia-inducible factor-1α expression. Acta Otolaryngol. 2014 Feb;134(2):185-92 Zhang C et al 2014/01/01 |
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| 406 |
Kawakami T et al. Prolonged endoplasmic reticulum stress alters placental morphology and causes low birth weight. Toxicol. Appl. Pharmacol. 2014 Mar;275(2):134-44 Kawakami T et al 2014/01/01 |
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| 407 |
Garofalo C et al. Metformin as an adjuvant drug against pediatric sarcomas: hypoxia limits therapeutic effects of the drug. PLoS ONE 2013;8(12):e83832 Garofalo C et al 2013/01/01 |
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| 408 |
Fujimura A et al. Cyclin G2 promotes hypoxia-driven local invasion of glioblastoma by orchestrating cytoskeletal dynamics. Neoplasia 2013 Nov;15(11):1272-81 Fujimura A et al 2013/01/01 |
|
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| 409 |
Chen TM et al. Overexpression of FGF9 in colon cancer cells is mediated by hypoxia-induced translational activation. Nucleic Acids Res. 2014 Mar;42(5):2932-44 Chen TM et al 2014/01/01 |
|
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| 410 |
Liu X et al. Prolyl Hydroxylase Inhibitors Protect from the Bone Loss in Ovariectomy Rats by Increasing Bone Vascularity. Cell Biochem. Biophys. 2013 Nov; Liu X et al 2013/01/01 |
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| 411 |
Ji X et al. Knockdown of Nrf2 suppresses glioblastoma angiogenesis by inhibiting hypoxia-induced activation of HIF-1α Int. J. Cancer 2013 Dec; Ji X et al 2013/01/01 |
|
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| 412 |
Fernandes BF et al. Hypoxia-Inducible Factor-1α and its Role in the Proliferation of Retinoblastoma Cells. Pathol. Oncol. Res. 2013 Dec; Fernandes BF et al 2013/01/01 |
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| 413 |
Zhang Y et al. Mitochondrial respiration regulates adipogenic differentiation of human mesenchymal stem cells. PLoS ONE 2013;8(10):e77077 Zhang Y et al 2013/01/01 |
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| 414 |
Chen Z et al. Prognostic value and clinicopathological differences of HIFs in colorectal cancer: evidence from meta-analysis. PLoS ONE 2013;8(12):e80337 Chen Z et al 2013/01/01 |
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| 415 |
Takano N et al. Hypoxia-inducible factors regulate human and rat cystathionine β-synthase gene expression. Biochem. J. 2014 Mar;458(2):203-11 Takano N et al 2014/01/01 |
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| 416 |
Ganapathy S et al. A Low-dose Arsenic-induced p53 Protein-mediated Metabolic Mechanism of Radiotherapy Protection. J. Biol. Chem. 2014 Feb;289(8):5340-7 Ganapathy S et al 2014/01/01 |
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| 417 |
Popescu CR et al. Hyperoxia exposure impairs nephrogenesis in the neonatal rat: role of HIF-1α. PLoS ONE 2013;8(12):e82421 Popescu CR et al 2013/01/01 |
|
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| 418 |
Kind KL et al. Oxygen-regulated gene expression in murine cumulus cells. Reprod. Fertil. Dev. 2014 Jan; Kind KL et al 2014/01/01 |
|
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| 419 |
Park EY et al. HNF4α contributes to glucose formation in aged rat hepatocytes. Exp. Gerontol. 2013 Dec;48(12):1518-25 Park EY et al 2013/01/01 |
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| 420 |
Vorrink SU et al. PCB 126 perturbs hypoxia-induced HIF-1α activity and glucose consumption in human HepG2 cells. Exp. Toxicol. Pathol. 2014 Oct;66(8):377-82 Vorrink SU et al 2014/01/01 |
Species: Rat, Applications: IHC-P | |
| 421 |
Funk K et al. Severe blunt muscle trauma in rats: only marginal hypoxia in the injured area. PLoS ONE 2014;9(10):e111151 Funk K et al 2014/01/01 |
Species: Rat, Applications: IHC-P | |
| 422 |
Kalamida D et al. Important role of autophagy in endothelial cell response to ionizing radiation. PLoS ONE 2014;9(7):e102408 Kalamida D et al 2014/01/01 |
Species: Human, Applications: WB | |
| 423 |
Bordji K et al. Hypoxia-inducible factor-2α (HIF-2α), but not HIF-1α, is essential for hypoxic induction of class III β-tubulin expression in human glioblastoma cells. FEBS J. 2014 Dec;281(23):5220-36 Bordji K et al 2014/01/01 |
Species: Human, Applications: WB, GS | |
| 424 |
Privat M et al. BRCA1 induces major energetic metabolism reprogramming in breast cancer cells. PLoS ONE 2014;9(7):e102438 Privat M et al 2014/01/01 |
Species: Human, Applications: WB | |
| 425 |
Zhou W et al. Only Very Early Oxygen Therapy Attenuates Posthemorrhagic Edema Formation and Blood-Brain Barrier Disruption in Murine Intracerebral Hemorrhage. Neurocrit Care 2014 Jul; Zhou W et al 2014/01/01 |
Species: Mouse, Applications: WB | |
| 426 |
Rahman SU et al. The prolyl hydroxylase inhibitor dimethyloxalylglycine enhances dentin sialophoshoprotein expression through VEGF-induced Runx2 stabilization. PLoS ONE 2014;9(11):e112078 Rahman SU et al 2014/01/01 |
Species: Rat, Applications: WB | |
| 427 |
Yang MY et al. An innovative three-dimensional gelatin foam culture system for improved study of glioblastoma stem cell behavior. J. Biomed. Mater. Res. Part B Appl. Biomater. 2014 Jun; Yang MY et al 2014/01/01 |
Species: Human, Applications: IHC | |
| 428 |
El Assar M et al. FM19G11 reverses endothelial dysfunction in rat and human arteries through stimulation of the PI3K/Akt/eNOS pathway, independently of mTOR/HIF-1α activation. Br. J. Pharmacol. 2014 Nov; El Assar M et al 2014/01/01 |
Species: Rat, Applications: WB | |
| 429 |
Wu JB et al. Near-infrared fluorescence imaging of cancer mediated by tumor hypoxia and HIF1α/OATPs signaling axis. Biomaterials 2014 Sep;35(28):8175-85 Wu JB et al 2014/01/01 |
Species: Human, Applications: IHC-P | |
| 430 |
Xiong Y et al. The local corticotropin-releasing hormone receptor 2 signalling pathway partly mediates hypoxia-induced increases in lipolysis via the cAMP-protein kinase A signalling pathway in white adipose tissue. Mol. Cell. Endocrinol. 2014 Jul;392(1-2 Xiong Y et al 2014/01/01 |
Species: Rat, Applications: WB | |
| 431 |
Matsumoto S et al. EPR oxygen imaging and hyperpolarized 13C MRI of pyruvate metabolism as noninvasive biomarkers of tumor treatment response to a glycolysis inhibitor 3-bromopyruvate. Magn Reson Med 2013 May;69(5):1443-50 Matsumoto S et al 2013/01/01 |
Species: Mouse, Applications: IHC-Fr, ICC/IF | |
| 432 |
Yoshikawa N et al. Down-regulation of hypoxia-inducible factor-1 alpha and vascular endothelial growth factor by HEXIM1 attenuates myocardial angiogenesis in hypoxic mice. Biochem. Biophys. Res. Commun. 2014 Oct;453(3):600-5 Yoshikawa N et al 2014/01/01 |
Species: Human, Applications: WB | |
| 433 |
Li Y et al. Expression of HIF-1α and MDR1/P-glycoprotein in refractory mesial temporal lobe epilepsy patients and pharmacoresistant temporal lobe epilepsy rat model kindled by coriaria lactone. Neurol. Sci. 2014 Aug;35(8):1203-8 Li Y et al 2014/01/01 |
Species: Rat, Applications: WB | |
| 434 |
Xu W et al. Influence of preoperative transcatheter arterial chemoembolization on gene expression in the HIF-1α pathway in patients with hepatocellular carcinoma. J. Cancer Res. Clin. Oncol. 2014 Sep;140(9):1507-15 Xu W et al 2014/01/01 |
Species: Human, Applications: IHC-P | |
| 435 |
Bertozzi D et al. The natural inhibitor of DNA topoisomerase I, camptothecin, modulates HIF-1α activity by changing miR expression patterns in human cancer cells. Mol. Cancer Ther. 2014 Jan;13(1):239-48 Bertozzi D et al 2014/01/01 |
Species: Human, Applications: WB | |
| 436 |
Pan WL et al. Preferential cytotoxicity of the type I ribosome inactivating protein alpha-momorcharin on human nasopharyngeal carcinoma cells under normoxia and hypoxia. Biochem. Pharmacol. 2014 Jun;89(3):329-39 Pan WL et al 2014/01/01 |
Species: Human, Applications: WB | |
| 437 |
Huang YH et al. Hypoxia inducible factor 2α/insulin-like growth factor receptor signal loop supports the proliferation and Oct-4 maintenance of mouse germline stem cells. Mol. Hum. Reprod. 2014 Jun;20(6):526-37 Huang YH et al 2014/01/01 |
Species: Mouse, Applications: WB | |
| 438 |
Pantel A et al. Direct type I IFN but not MDA5/TLR3 activation of dendritic cells is required for maturation and metabolic shift to glycolysis after poly IC stimulation. PLoS Biol. 2014 Jan;12(1):e1001759 Pantel A et al 2014/01/01 |
Species: Mouse, Applications: FLOW | |
| 439 |
White NM et al. Galectin-1 has potential prognostic significance and is implicated in clear cell renal cell carcinoma progression through the HIF/mTOR signaling axis. Br. J. Cancer 2014 Mar;110(5):1250-9 White NM et al 2014/01/01 |
Species: Human, Applications: WB | |
| 440 |
Zhao L et al. Upregulation of HIF-1α via activation of ERK and PI3K pathway mediated protective response to microwave-induced mitochondrial injury in neuron-like cells. Mol. Neurobiol. 2014 Dec;50(3):1024-34 Zhao L et al 2014/01/01 |
Species: Rat, Applications: WB | |
| 441 |
Kim YS et al. β-Carotene inhibits neuroblastoma cell invasion and metastasis in vitro and in vivo by decreasing level of hypoxia-inducible factor-1α. J. Nutr. Biochem. 2014 Jun;25(6):655-64 Kim YS et al 2014/01/01 |
Species: Human, Applications: WB, IHC-P | |
| 442 |
Shinohara M et al. Cell-cell interactions and bronchoconstrictor eicosanoid reduction with inhaled carbon monoxide and resolvin D1. Am. J. Physiol. Lung Cell Mol. Physiol. 2014 Nov;307(10):L746-57 Shinohara M et al 2014/01/01 |
Species: Human, Applications: ICC/IF | |
| 443 |
He M et al. MiRNA-210 modulates a nickel-induced cellular energy metabolism shift by repressing the iron-sulfur cluster assembly proteins ISCU1/2 in Neuro-2a cells. Cell Death Dis 2014;5:e1090 He M et al 2014/01/01 |
Species: Mouse, Applications: WB | |
| 444 |
Mateo J et al. Noninvasive assessment of hypoxia in rabbit advanced atherosclerosis using ¹⁸F-fluoromisonidazole positron emission tomographic imaging. Circ Cardiovasc Imaging 2014 Mar;7(2):312-20 Mateo J et al 2014/01/01 |
Species: Human, Applications: IHC-P | |
| 445 |
Zhao W et al. Steroid receptor coactivator-3 regulates glucose metabolism in bladder cancer cells through coactivation of hypoxia inducible factor 1α. J. Biol. Chem. 2014 Apr;289(16):11219-29 Zhao W et al 2014/01/01 |
Species: Human, Applications: ChIP | |
| 446 |
Kasper LH et al. Genome-wide and single-cell analyses reveal a context dependent relationship between CBP recruitment and gene expression. Nucleic Acids Res. 2014 Oct;42(18):11363-82 Kasper LH et al 2014/01/01 |
Species: Mouse, Applications: ChIP | |
| 447 |
Zhang WG et al. Regulation of transplanted mesenchymal stem cells by the lung progenitor niche in rats with chronic obstructive pulmonary disease. Respir. Res. 2014;15:33 Zhang WG et al 2014/01/01 |
Species: Rat, Applications: IHC-P, WB | |
| 448 |
Samanta D et al. Hypoxia-inducible factors are required for chemotherapy resistance of breast cancer stem cells. Proc. Natl. Acad. Sci. U.S.A. 2014 Dec;111(50):E5429-38 Samanta D et al 2014/01/01 |
Species: Human, Applications: WB | |
| 449 |
Chen Z et al. EAF2 suppresses hypoxia-induced factor 1α transcriptional activity by disrupting its interaction with coactivator CBP/p300. Mol. Cell. Biol. 2014 Mar;34(6):1085-99 Chen Z et al 2014/01/01 |
Species: Human, Applications: WB | |
| 450 |
Lee HS et al. Priming Wharton's Jelly-Derived Mesenchymal Stromal/Stem Cells With ROCK Inhibitor Improves Recovery in an Intracerebral Hemorrhage Model. J. Cell. Biochem. 2015 Feb;116(2):310-9 Lee HS et al 2015/01/01 |
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| 451 |
Shan F et al. HIF-1 alpha-induced up-regulation of miR-9 contributes to phenotypic modulation in pulmonary artery smooth muscle cells during hypoxia. J. Cell. Physiol. 2014 Oct;229(10):1511-20 Shan F et al 2014/01/01 |
Species: Rat, Applications: WB | |
| 452 |
Cheng YL et al. Evidence that collaboration between HIF-1α and Notch-1 promotes neuronal cell death in ischemic stroke. Neurobiol. Dis. 2014 Feb;62:286-95 Cheng YL et al 2014/01/01 |
Species: Mouse, Applications: WB, ICC/IF | |
| 453 |
Huang T et al. Hypoxia-inducible factor-1α upregulation in microglia following hypoxia protects against ischemia-induced cerebral infarction. Neuroreport 2014 Oct;25(14):1122-8 Huang T et al 2014/01/01 |
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| 454 |
Chang ML et al. High glucose activates ChREBP-mediated HIF-1α and VEGF expression in human RPE cells under normoxia. Adv. Exp. Med. Biol. 2014;801:609-21 Chang ML et al 2014/01/01 |
Species: Human, Applications: WB | |
| 455 |
Lall R et al. Low-dose radiation exposure induces a HIF-1-mediated adaptive and protective metabolic response. Cell Death Differ. 2014 May;21(5):836-44 Lall R et al 2014/01/01 |
Species: Human, Applications: ICC/IF | |
| 456 |
Marhold M et al. HIF-1alpha Regulates mTOR Signaling and Viability of Prostate Cancer Stem Cells. Mol. Cancer Res. 2014 Oct; Marhold M et al 2014/01/01 |
Species: Human, Mouse, Applications: WB, IP | |
| 457 |
Sato Y et al. The vitamin D analogue ED71 but Not 1,25(OH)2D3 targets HIF1α protein in osteoclasts. PLoS ONE 2014;9(11):e111845 Sato Y et al 2014/01/01 |
Species: Mouse, Applications: WB | |
| 458 |
Weisel FC et al. Impact of S-adenosylmethionine decarboxylase 1 on pulmonary vascular remodeling. Circulation 2014 Apr;129(14):1510-23 Weisel FC et al 2014/01/01 |
Species: Mouse, Human, Applications: ChIP | |
| 459 |
Gu J et al. SENP1 protects against myocardial ischaemia/reperfusion injury via a HIF1α-dependent pathway. Cardiovasc. Res. 2014 Oct;104(1):83-92 Gu J et al 2014/01/01 |
Species: Rat, Applications: WB, IP | |
| 460 |
Huang SM et al. GDNF increases cell motility in human colon cancer through VEGF-VEGFR1 interaction. Endocr. Relat. Cancer 2014 Feb;21(1):73-84 Huang SM et al 2014/01/01 |
Species: Human, Applications: WB | |
| 461 |
Raspaglio G et al. Sox9 and Hif-2α regulate TUBB3 gene expression and affect ovarian cancer aggressiveness. Gene 2014 Jun;542(2):173-81 Raspaglio G et al 2014/01/01 |
Species: Human, Applications: WB | |
| 462 |
Imamura Y et al. HIF-2α/ARNT complex regulates hair development via induction of p21(Waf1/Cip1) and p27(Kip1). FASEB J. 2014 Jun;28(6):2517-24 Imamura Y et al 2014/01/01 |
Species: Mouse, Applications: WB | |
| 463 |
Wu X et al. Impaired autophagy contributes to adverse cardiac remodeling in acute myocardial infarction. PLoS ONE 2014;9(11):e112891 Wu X et al 2014/01/01 |
Species: Mouse, Applications: WB | |
| 464 |
Zheng J et al. Dynamic hypoxia in scar tissue during human hypertrophic scar progression. Dermatol Surg 2014 May;40(5):511-8 Zheng J et al 2014/01/01 |
Species: Human, Applications: IHC-P | |
| 465 |
Arreola A et al. HIF1α and HIF2α exert distinct nutrient preferences in renal cells. PLoS ONE 2014;9(5):e98705 Arreola A et al 2014/01/01 |
Species: Mouse, Applications: WB | |
| 466 |
Sano M et al. Lymphangiogenesis and angiogenesis in abdominal aortic aneurysm. PLoS ONE 2014;9(3):e89830 Sano M et al 2014/01/01 |
Species: Human, Applications: IHC-P | |
| 467 |
Jeong S et al. Lipophilic modification enhances anti-colitic properties of rosmarinic acid by potentiating its HIF-prolyl hydroxylases inhibitory activity. Eur. J. Pharmacol. 2015 Jan;747:114-22 Jeong S et al 2015/01/01 |
Species: Human, Applications: WB | |
| 468 |
Gillespie DL et al. RNA interference targeting hypoxia-inducible factor 1α via a novel multifunctional surfactant attenuates glioma growth in an intracranial mouse model. J. Neurosurg. 2015 Feb;122(2):331-41 Gillespie DL et al 2015/01/01 |
Species: Human, Applications: IHC-P | |
| 469 |
Rutz S et al. Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells. Nature 2015 Feb;518(7539):417-21 Rutz S et al 2015/01/01 |
Species: Mouse, Applications: WB | |
| 470 |
Hung YH et al. Inhibitor of Differentiation-1 and Hypoxia-Inducible Factor-1 Mediate Sonic Hedgehog Induction by Amyloid Beta-Peptide in Rat Cortical Neurons. Mol. Neurobiol. 2014 Dec; Hung YH et al 2014/01/01 |
Species: Rat, Applications: ChIP | |
| 471 |
Queisser MA et al. HOIL-1L functions as the PKCζ ubiquitin ligase to promote lung tumor growth. Am. J. Respir. Crit. Care Med. 2014 Sep;190(6):688-98 Queisser MA et al 2014/01/01 |
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| 472 |
Li R et al. Hypoxia-inducible factor-1α regulates the expression of L-type voltage-dependent Ca(2+) channels in PC12 cells under hypoxia. Cell Stress Chaperones 2015 Feb; Li R et al 2015/01/01 |
Species: Rat, Applications: WB | |
| 473 |
Hasan AU et al. Eicosapentaenoic acid upregulates VEGF-A through both GPR120 and PPARγ mediated pathways in 3T3-L1 adipocytes. Mol. Cell. Endocrinol. 2015 May;406:10-8 Hasan AU et al 2015/01/01 |
Species: Mouse, Applications: WB | |
| 474 |
Paeng SH et al. Caffeic acid phenethyl ester reduces the secretion of vascular endothelial growth factor through the inhibition of the ROS, PI3K and HIF-1α signaling pathways in human retinal pigment epithelial cells under hypoxic conditions. Int. J Paeng SH et al 2015/01/01 |
Species: Human, Applications: WB | |
| 475 |
Salman S et al. Chronic opioids regulate KATP channel subunit Kir6.2 and carbonic anhydrase I and II expression in rat adrenal chromaffin cells via HIF-2α and protein kinase A. Am. J. Physiol., Cell Physiol. 2014 Aug;307(3):C266-77 Salman S et al 2014/01/01 |
Species: Rat, | |
| 476 |
Huang M et al. Overexpression of hypoxia-inducible factor-1α is a predictor of poor prognosis in cervical cancer: a clinicopathologic study and a meta-analysis. Int. J. Gynecol. Cancer 2014 Jul;24(6):1054-64 Huang M et al 2014/01/01 |
Species: Human, | |
| 477 |
Narise K et al. Optimization of biguanide derivatives as selective antitumor agents blocking adaptive stress responses in the tumor microenvironment. Drug Des Devel Ther 2014;8:701-17 Narise K et al 2014/01/01 |
Applications: WB | |
| 478 |
Wang WS et al. DMOG ameliorates IFN-γ-induced intestinal barrier dysfunction by suppressing PHD2-dependent HIF-1α degradation. J. Interferon Cytokine Res. 2014 Jan;34(1):60-9 Wang WS et al 2014/01/01 |
Species: Human, | |
| 479 |
He YL et al. Enhanced hypoxia-inducible factor (HIF)-1α stability induced by 5-hydroxymethyl-2-furfural (5-HMF) contributes to protection against hypoxia. Mol. Med. 2014;20:590-600 He YL et al 2014/01/01 |
Species: Mouse, Rat, Applications: WB, ICC/IF | |
| 480 |
Bohuslavova R et al. Partial deficiency of HIF-1α stimulates pathological cardiac changes in streptozotocin-induced diabetic mice. BMC Endocr Disord 2014;14:11 Bohuslavova R et al 2014/01/01 |
Species: Mouse, Applications: WB | |
| 481 |
Gauter-Fleckenstein B et al. Robust rat pulmonary radioprotection by a lipophilic Mn N-alkylpyridylporphyrin, MnTnHex-2-PyP(5+). Redox Biol 2014;2:400-10 Gauter-Fleckenstein B et al 2014/01/01 |
Species: Rat, Applications: IHC | |
| 482 |
Srivastava S et al. Expression of proteins associated with hypoxia and Wnt pathway activation is of prognostic significance in hepatocellular carcinoma. Virchows Arch. 2015 May;466(5):541-8 Srivastava S et al 2015/01/01 |
Species: Human, Applications: IHC-P | |
| 483 |
Wang F et al. Renalase contributes to the renal protection of delayed ischaemic preconditioning via the regulation of hypoxia-inducible factor-1α. J. Cell. Mol. Med. 2015 Jun;19(6):1400-9 Wang F et al 2015/01/01 |
Species: Human, Applications: WB | |
| 484 |
Zhang X et al. Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments. Nat Commun 2014;5:3295 Zhang X et al 2014/01/01 |
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| 485 |
Przybyla BD et al. Molecular changes in bone marrow, tumor and serum after conductive ablation of murine 4T1 breast carcinoma. Int. J. Oncol. 2014 Feb;44(2):600-8 Przybyla BD et al 2014/01/01 |
Applications: WB | |
| 486 |
Yang X et al. Melittin enhances radiosensitivity of hypoxic head and neck squamous cell carcinoma by suppressing HIF-1α. Tumour Biol. 2014 Oct;35(10):10443-8 Yang X et al 2014/01/01 |
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| 487 |
Chen J et al. Clinical and prognostic significance of HIF-1α, PTEN, CD44v6, and survivin for gastric cancer: a meta-analysis. PLoS ONE 2014;9(3):e91842 Chen J et al 2014/01/01 |
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| 488 |
Fillmore N et al. Effect of fatty acids on human bone marrow mesenchymal stem cell energy metabolism and survival. PLoS ONE 2015;10(3):e0120257 Fillmore N et al 2015/01/01 |
Species: Human, Applications: WB | |
| 489 |
Schiffer D et al. Stem cell niches in glioblastoma: a neuropathological view. Biomed Res Int 2014;2014:725921 Schiffer D et al 2014/01/01 |
Species: Human, | |
| 490 |
Chan MC et al. Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain. PLoS ONE 2015;10(7):e0132004 Chan MC et al 2015/01/01 |
Species: Human, Applications: IA | |
| 491 |
Yu MO et al. Reactive oxygen species production has a critical role in hypoxia-induced Stat3 activation and angiogenesis in human glioblastoma. J. Neurooncol. 2015 Oct;125(1):55-63 Yu MO et al 2015/01/01 |
Species: Human, Applications: WB | |
| 492 |
Wong CS et al. Loss of Siah2 does not impact angiogenic potential of murine endothelial cells. Microvasc. Res. 2015 Nov;102:38-45 Wong CS et al 2015/01/01 |
Species: Mouse, Applications: WB | |
| 493 |
Nakatani K et al. Myocardial energy provision is preserved by increased utilization of glucose and ketone bodies in CD36 knockout mice. Metab. Clin. Exp. 2015 Sep;64(9):1165-74 Nakatani K et al 2015/01/01 |
Species: Mouse, Applications: WB | |
| 494 |
He Q et al. Regulation of HIF-1{alpha} activity in adipose tissue by obesity-associated factors: adipogenesis, insulin, and hypoxia. Am. J. Physiol. Endocrinol. Metab. 2011 May;300(5):E877-85 He Q et al 2011/01/01 |
Species: Human, Applications: ICC/IF | |
| 495 |
Kazi AA et al. Chromatin immunoprecipitation analysis of gene expression in the rat uterus in vivo: estrogen-induced recruitment of both estrogen receptor alpha and hypoxia-inducible factor 1 to the vascular endothelial growth factor promoter. Mol. Endocr Kazi AA et al 2005/01/01 |
Applications: WB | |
| 496 |
Arsham AM et al. Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1 alpha nor sufficient for HIF-1-dependent target gene transcription. J. Biol. Chem. 2002 Apr;277(17):15162-70 Arsham AM et al 2002/01/01 |
Applications: WB | |
| 497 |
Pascual O et al. Selective cardiorespiratory and catecholaminergic areas express the hypoxia-inducible factor-1alpha (HIF-1alpha) under in vivo hypoxia in rat brainstem. Eur. J. Neurosci. 2001 Dec;14(12):1981-91 Pascual O et al 2001/01/01 |
Species: Rat, Applications: ICC/IF | |
| 498 |
Milkiewicz M et al. Identification of a mechanism underlying regulation of the anti-angiogenic forkhead transcription factor FoxO1 in cultured endothelial cells and ischemic muscle. Am. J. Pathol. 2011 Feb;178(2):935-44 Milkiewicz M et al 2011/01/01 |
Species: Rat, Applications: WB | |
| 499 |
Colbert LE et al. High nuclear hypoxia-inducible factor 1 alpha expression is a predictor of distant recurrence in patients with resected pancreatic adenocarcinoma. Int. J. Radiat. Oncol. Biol. Phys. 2015 Mar;91(3):631-9 Colbert LE et al 2015/01/01 |
Species: Human | |
| 500 |
Hayashi M et al. Up-regulation of c-met protooncogene product expression through hypoxia-inducible factor-1alpha is involved in trophoblast invasion under low-oxygen tension. Endocrinology 2005 Nov;146(11):4682-9 Hayashi M et al 2005/01/01 |
Species: Human, Applications: ChIP | |
| 501 |
Park H et al. 3,3'-Diindolylmethane inhibits VEGF expression through the HIF-1α and NF-κB pathways in human retinal pigment epithelial cells under chemical hypoxic conditions. Int. J. Mol. Med. 2015 Jul;36(1):301-8 Park H et al 2015/01/01 |
Species: Human, Applications: WB | |
| 502 |
Tissot van Patot MC et al. Greater vascularity, lowered HIF-1/DNA binding, and elevated GSH as markers of adaptation to in vivo chronic hypoxia. Am. J. Physiol. Lung Cell Mol. Physiol. 2004 Sep;287(3):L525-32 Tissot van Patot MC et al 2004/01/01 |
Species: Human, Applications: WB | |
| 503 |
Hammami A et al. IRF-5-Mediated Inflammation Limits CD8+ T Cell Expansion by Inducing HIF-1α and Impairing Dendritic Cell Functions during Leishmania Infection. PLoS Pathog. 2015 Jun;11(6):e1004938 Hammami A et al 2015/01/01 |
Species: Mouse, Applications: WB | |
| 504 |
Belo AI et al. Hypoxia inducible factor 1α down regulates cell surface expression of α1,2-fucosylated glycans in human pancreatic adenocarcinoma cells. FEBS Lett. 2015 Aug;589(18):2359-66 Belo AI et al 2015/01/01 |
Species: Human, Applications: ICC/IF | |
| 505 |
Mashiko R et al. Hypoxia-inducible factor 1α expression is a prognostic biomarker in patients with astrocytic tumors associated with necrosis on MR image. J. Neurooncol. 2011 Mar;102(1):43-50 Mashiko R et al 2011/01/01 |
Species: Human, Applications: ELISA | |
| 506 |
Kumar P et al. Estrogen-related receptor gamma (ERRgamma) mediates oxygen-dependent induction of aromatase (CYP19) gene expression during human trophoblast differentiation. Mol. Endocrinol. 2011 Sep;25(9):1513-26 Kumar P et al 2011/01/01 |
Species: Human, Applications: ChIP | |
| 507 |
Takata S et al. The effect of triamcinolone acetonide on laser-induced choroidal neovascularization in mice using a hypoxia visualization bio-imaging probe. Sci Rep 2015;5:9898 Takata S et al 2015/01/01 |
Species: Mouse, Human, Applications: WB | |
| 508 |
Mizokami K et al. Relationship of hypoxia-inducible factor 1alpha and p21WAF1/CIP1 expression to cell apoptosis and clinical outcome in patients with gastric cancer. World J Surg Oncol 2006;4:94 Mizokami K et al 2006/01/01 |
Applications: IHC | |
| 509 |
Zhang W et al. Evidence that hypoxia-inducible factor-1 (HIF-1) mediates transcriptional activation of interleukin-1beta (IL-1beta) in astrocyte cultures. J. Neuroimmunol. 2006 May;174(1-2):63-73 Zhang W et al 2006/01/01 |
Applications: ELISA | |
| 510 |
Rouschop KM et al. The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5. J. Clin. Invest. 2010 Jan;120(1):127-41 Rouschop KM et al 2010/01/01 |
Applications: ChIP | |
| 511 |
Schindl M et al. DNA repair-redox enzyme apurinic endonuclease in cervical cancer: evaluation of redox control of HIF-1alpha and prognostic significance. Int. J. Oncol. 2001 Oct;19(4):799-802 Schindl M et al 2001/01/01 |
Species: Human | |
| 512 |
Yamada T et al. Correlation of metabolism/hypoxia markers and fluorodeoxyglucose uptake in oral squamous cell carcinomas. Oral Surg Oral Med Oral Pathol Oral Radiol 2012 Apr;113(4):464-71 Yamada T et al 2012/01/01 |
Species: Human, Applications: IHC | |
| 513 |
Wang WK et al. Connexin 43 suppresses tumor angiogenesis by down-regulation of vascular endothelial growth factor via hypoxic-induced factor-1α. Int J Mol Sci 2015;16(1):439-51 Wang WK et al 2015/01/01 |
Species: Mouse, Applications: WB, ELISA | |
| 514 |
Joo HY et al. SIRT1 deacetylates and stabilizes hypoxia-inducible factor-1α (HIF-1α) via direct interactions during hypoxia. Biochem. Biophys. Res. Commun. 2015 Jul;462(4):294-300 Joo HY et al 2015/01/01 |
Species: Human, Applications: IP, WB | |
| 515 |
Nakamura J et al. Hypoxia-inducible factor-1alpha expression predicts the response to 5-fluorouracil-based adjuvant chemotherapy in advanced gastric cancer. Oncol. Rep. 2009 Oct;22(4):693-9 Nakamura J et al 2009/01/01 |
Species: Human, Applications: IHC | |
| 516 |
Zhang Z et al. Overexpression of hypoxia-inducible factor prolyl hydoxylase-2 attenuates hypoxia-induced vascular endothelial growth factor expression in luteal cells. Mol Med Rep 2015 Sep;12(3):3809-14 Zhang Z et al 2015/01/01 |
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| 517 |
Gauter-Fleckenstein B et al. Early and late administration of MnTE-2-PyP5+ in mitigation and treatment of radiation-induced lung damage. Free Radic. Biol. Med. 2010 Apr;48(8):1034-43 Gauter-Fleckenstein B et al 2010/01/01 |
Species: Rat, Applications: IHC | |
| 518 |
Des Tombe AL et al. Calibrated histochemistry applied to oxygen supply and demand in hypertrophied rat myocardium. Microsc. Res. Tech. 2002 Sep;58(5):412-20 Des Tombe AL et al 2002/01/01 |
Species: Rat, Applications: IHC | |
| 519 |
Silver MI et al. Shedding of Epstein-Barr virus and cytomegalovirus from the genital tract of women in a periurban community in Andhra Pradesh, India. J. Clin. Microbiol. 2011 Jul;49(7):2435-9 Silver MI et al 2011/01/01 |
Applications: ChIP | |
| 520 |
Fan Y et al. Local renin-angiotensin system regulates hypoxia-induced vascular endothelial growth factor synthesis in mesenchymal stem cells. Int J Clin Exp Pathol 2015;8(3):2505-14 Fan Y et al 2015/01/01 |
Species: Rat, Applications: WB | |
| 521 |
Shao J et al. HIF-1α disturbs osteoblasts and osteoclasts coupling in bone remodeling by up-regulating OPG expression. In Vitro Cell. Dev. Biol. Anim. 2015 Sep;51(8):808-14 Shao J et al 2015/01/01 |
Species: Mouse, Applications: WB, ChIP | |
| 522 |
Fernando MS et al. White matter lesions in an unselected cohort of the elderly: molecular pathology suggests origin from chronic hypoperfusion injury. Stroke 2006 Jun;37(6):1391-8 Fernando MS et al 2006/01/01 |
Species: Human | |
| 523 |
Komatsu DE et al. Enhanced bone regeneration associated with decreased apoptosis in mice with partial HIF-1alpha deficiency. J. Bone Miner. Res. 2007 Mar;22(3):366-74 Komatsu DE et al 2007/01/01 |
Species: Mouse, Applications: WB | |
| 524 |
Wang Y et al. Gene inactivation of Na+/H+ exchanger isoform 1 attenuates apoptosis and mitochondrial damage following transient focal cerebral ischemia. Eur. J. Neurosci. 2008 Jul;28(1):51-61 Wang Y et al 2008/01/01 |
Species: Mouse | |
| 525 |
Mimouna S et al. Crohn disease-associated Escherichia coli promote gastrointestinal inflammatory disorders by activation of HIF-dependent responses. Gut Microbes ;2(6):335-46 Mimouna S et al |
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| 526 |
Nakamura K et al. NGF activation of TrkA induces vascular endothelial growth factor expression via induction of hypoxia-inducible factor-1α. Mol. Cell. Neurosci. 2011 Feb;46(2):498-506 Nakamura K et al 2011/01/01 |
Species: Mouse | |
| 527 |
Babu E et al. Deletion of the amino acid transporter Slc6a14 suppresses tumor growth in spontaneous mouse models of breast cancer. Biochem. J. 2015 May; Babu E et al 2015/01/01 |
Species: Mouse, Applications: IHC-P | |
| 528 |
Sun L et al. A Novel Role of OS-9 in the Maintenance of Intestinal Barrier Function from Hypoxia-induced Injury via p38-dependent Pathway. Int. J. Biol. Sci. 2015;11(6):664-71 Sun L et al 2015/01/01 |
Applications: WB | |
| 529 |
Swinson DE et al. Hypoxia-inducible factor-1 alpha in non small cell lung cancer: relation to growth factor, protease and apoptosis pathways. Int. J. Cancer 2004 Aug;111(1):43-50 Swinson DE et al 2004/01/01 |
Species: Human, Applications: IP | |
| 530 |
Li YM et al. A hypoxia-independent hypoxia-inducible factor-1 activation pathway induced by phosphatidylinositol-3 kinase/Akt in HER2 overexpressing cells. Cancer Res. 2005 Apr;65(8):3257-63 Li YM et al 2005/01/01 |
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| 531 |
Lee JH et al. E3 Ubiquitin Ligase VHL Regulates Hypoxia-Inducible Factor-1α to Maintain Regulatory T Cell Stability and Suppressive Capacity. Immunity 2015 Jun;42(6):1062-74 Lee JH et al 2015/01/01 |
Species: Mouse, Applications: ChIP | |
| 532 |
Schoppmann SF et al. Hypoxia inducible factor-1alpha correlates with VEGF-C expression and lymphangiogenesis in breast cancer. Breast Cancer Res. Treat. 2006 Sep;99(2):135-41 Schoppmann SF et al 2006/01/01 |
Species: Human, Applications: IHC | |
| 533 |
Albina JE et al. HIF-1 expression in healing wounds: HIF-1alpha induction in primary inflammatory cells by TNF-alpha. Am. J. Physiol., Cell Physiol. 2001 Dec;281(6):C1971-7 Albina JE et al 2001/01/01 |
Species: Rat | |
| 534 |
Grammas P et al. Thrombin and inflammatory proteins are elevated in Alzheimer's disease microvessels: implications for disease pathogenesis. J. Alzheimers Dis. 2006 Mar;9(1):51-8 Grammas P et al 2006/01/01 |
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| 535 |
Espana-Agusti J et al. A minimally invasive, lentiviral based method for the rapid and sustained genetic manipulation of renal tubules. Sci Rep 2015;5:11061 Espana-Agusti J et al 2015/01/01 |
Species: Mouse, Applications: IHC | |
| 536 |
Deng A et al. Renal protection in chronic kidney disease: hypoxia-inducible factor activation vs. angiotensin II blockade. Am. J. Physiol. Renal Physiol. 2010 Dec;299(6):F1365-73 Deng A et al 2010/01/01 |
Species: Rat, Applications: WB | |
| 537 |
Mace KA et al. Sustained expression of Hif-1alpha in the diabetic environment promotes angiogenesis and cutaneous wound repair. Wound Repair Regen ;15(5):636-45 Mace KA et al |
Species: Mouse, Applications: WB | |
| 538 |
Liu MY et al. Up-regulation of hypoxia-inducible factor 2alpha in renal cell carcinoma associated with loss of Tsc-2 tumor suppressor gene. Cancer Res. 2003 May;63(10):2675-80 Liu MY et al 2003/01/01 |
Species: Rat | |
| 539 |
Bullock JJ et al. Hyperglycemia-enhanced ischemic brain damage in mutant manganese SOD mice is associated with suppression of HIF-1alpha. Neurosci. Lett. 2009 Jun;456(2):89-92 Bullock JJ et al 2009/01/01 |
Species: Mouse | |
| 540 |
Wykoff CC et al. Gene array of VHL mutation and hypoxia shows novel hypoxia-induced genes and that cyclin D1 is a VHL target gene. Br. J. Cancer 2004 Mar;90(6):1235-43 Wykoff CC et al 2004/01/01 |
Species: Human | |
| 541 |
Miyazaki Y et al. The effect of hypoxic microenvironment on matrix metalloproteinase expression in xenografts of human oral squamous cell carcinoma. Int. J. Oncol. 2008 Jan;32(1):145-51 Miyazaki Y et al 2008/01/01 |
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| 542 |
Shintani K et al. Expression of hypoxia-inducible factor (HIF)-1alpha as a biomarker of outcome in soft-tissue sarcomas. Virchows Arch. 2006 Dec;449(6):673-81 Shintani K et al 2006/01/01 |
Species: Human, Applications: IHC | |
| 543 |
Maltepe E et al. Hypoxia-inducible factor-dependent histone deacetylase activity determines stem cell fate in the placenta. Development 2005 Aug;132(15):3393-403 Maltepe E et al 2005/01/01 |
Species: Mouse, Applications: WB | |
| 544 |
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Schokrpur S et al. CRISPR-Mediated VHL Knockout Generates an Improved Model for Metastatic Renal Cell Carcinoma. Sci Rep 2016;6:29032 Schokrpur S et al 2016/01/01 |
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Stei MM et al. Impact of macrophages on tumor growth characteristics in a murine ocular tumor model. Exp. Eye Res. 2016 Oct;151:9-18 Stei MM et al 2016/01/01 |
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Sanagawa A et al. Sphingosine 1‑phosphate induced by hypoxia increases the expression of PAI‑1 in HepG2 cells via HIF‑1α. Mol Med Rep 2016 Aug;14(2):1841-8 Sanagawa A et al 2016/01/01 |
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Luo B et al. ATP-Dependent Lon Protease Contributes to Helicobacter pylori-Induced Gastric Carcinogenesis. Neoplasia 2016 Apr;18(4):242-52 Luo B et al 2016/01/01 |
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Manisterski M et al. Hypoxia induces PTHrP gene transcription in human cancer cells through the HIF-2α. Cell Cycle 2010 Sep;9(18):3723-9 Manisterski M et al 2010/01/01 |
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Frew IJ et al. pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation. EMBO J. 2008 Jun;27(12):1747-57 Frew IJ et al 2008/01/01 |
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Miyagi E et al. Antibody-mediated enhancement of HIV-1 and HIV-2 production from BST-2/tetherin-positive cells. J. Virol. 2011 Nov;85(22):11981-94 Miyagi E et al 2011/01/01 |
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Xu X et al. Delayed ischemic preconditioning contributes to renal protection by upregulation of miR-21. Kidney Int. 2012 Dec;82(11):1167-75 Xu X et al 2012/01/01 |
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Das S et al. Protection of retinal cells from ischemia by a novel gap junction inhibitor. Biochem. Biophys. Res. Commun. 2008 Sep;373(4):504-8 Das S et al 2008/01/01 |
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Rankin EB et al. Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo. J. Clin. Invest. 2007 Apr;117(4):1068-77 Rankin EB et al 2007/01/01 |
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Zhang J et al. p16 Modulates VEGF expression via its interaction with HIF-1alpha in breast cancer cells. Cancer Invest. 2010 Jul;28(6):588-97 Zhang J et al 2010/01/01 |
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Behan A et al. Adaptive responses to mitochondrial dysfunction in the rho degrees Namalwa cell. Mitochondrion 2005 Jun;5(3):173-93 Behan A et al 2005/01/01 |
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| 603 |
Irie N et al. Protocol of radiotherapy for glioblastoma according to the expression of HIF-1. Brain Tumor Pathol 2004;21(1):1-6 Irie N et al 2004/01/01 |
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Stevens HY et al. Pressure gradients and transport in the murine femur upon hindlimb suspension. Bone 2006 Sep;39(3):565-72 Stevens HY et al 2006/01/01 |
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Liu X et al. Repression of hypoxia-inducible factor α signaling by Set7-mediated methylation. Nucleic Acids Res. 2015 May;43(10):5081-98 Liu X et al 2015/01/01 |
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Chou YT et al. C/EBP homologous binding protein (CHOP) underlies neural injury in sleep apnea model. Sleep 2013 Apr;36(4):481-92 Chou YT et al 2013/01/01 |
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Mazar J et al. MicroRNA 211 Functions as a Metabolic Switch in Human Melanoma Cells. Mol. Cell. Biol. 2016 Apr;36(7):1090-108 Mazar J et al 2016/01/01 |
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Chan N et al. Attenuation of choroidal neovascularization by histone deacetylase inhibitor. PLoS ONE 2015;10(3):e0120587 Chan N et al 2015/01/01 |
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Yatabe N et al. HIF-1-mediated activation of telomerase in cervical cancer cells. Oncogene 2004 Apr;23(20):3708-15 Yatabe N et al 2004/01/01 |
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Cui J et al. MBD3 mediates epigenetic regulation on EPAS1 promoter in cancer. Tumour Biol. 2016 Jul; Cui J et al 2016/01/01 |
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Lee SB et al. An ID2-dependent mechanism for VHL inactivation in cancer. Nature 2016 Jan;529(7585):172-7 Lee SB et al 2016/01/01 |
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Reichner JS et al. Determination of the role of hypoxia-inducible factor 1 in wound healing. Meth. Enzymol. 2004;381:527-38 Reichner JS et al 2004/01/01 |
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Dews M et al. Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster. Nat. Genet. 2006 Sep;38(9):1060-5 Dews M et al 2006/01/01 |
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Rees ML et al. A PKM2 signature in the failing heart. Biochem. Biophys. Res. Commun. 2015 Apr;459(3):430-6 Rees ML et al 2015/01/01 |
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Tu TC et al. A Chemokine Receptor, CXCR4, Which Is Regulated by Hypoxia-Inducible Factor 2α, Is Crucial for Functional Endothelial Progenitor Cells Migration to Ischemic Tissue and Wound Repair. Stem Cells Dev. 2016 Feb;25(3):266-76 Tu TC et al 2016/01/01 |
Species: Mouse, Applications: WB, ChIP | |
| 616 |
Lopez-Pascual A et al. Inflammation stimulates hypoxia-inducible factor-1α regulatory activity in 3T3-L1 adipocytes with conditioned medium from lipopolysaccharide-activated RAW 264.7 macrophages. J. Cell. Physiol. 2018 Jan;234(1):550-560 Lopez-Pascual A et al 2018/01/01 |
Species: Mouse, Applications: IP | |
| 617 |
Tatli Dogan H et al. Prognostic significance of the programmed death ligand 1 expression in clear cell renal cell carcinoma and correlation with the tumor microenvironment and hypoxia-inducible factor expression. Diagn Pathol 2018 Aug;13(1):60 Tatli Dogan H et al 2018/01/01 |
Species: Human, Applications: IHC | |
| 618 |
Wang JY et al. Dictamnine promotes apoptosis and inhibits epithelial-mesenchymal transition, migration, invasion and proliferation by downregulating the HIF-1α and Slug signaling pathways. Chem. Biol. Interact. 2018 Dec;296:134-144 Wang JY et al 2018/01/01 |
Species: Human, Applications: WB | |
| 619 |
Ha SD et al. Histone deacetylase 8 protects human proximal tubular epithelial cells from hypoxia-mimetic cobalt- and hypoxia/reoxygenation-induced mitochondrial fission and cytotoxicity. Sci Rep 2018 Jul;8(1):11332 Ha SD et al 2018/01/01 |
Species: Human, Applications: WB | |
| 620 |
Hammers HJ et al. Reversible epithelial to mesenchymal transition and acquired resistance to sunitinib in patients with renal cell carcinoma: evidence from a xenograft study. Mol. Cancer Ther. 2010 Jun;9(6):1525-35 Hammers HJ et al 2010/01/01 |
Species: Mouse, Applications: IHC | |
| 621 |
Li X et al. Therapeutic Potential of a Prolyl Hydroxylase Inhibitor FG-4592 for Parkinson's Diseases <i>in Vitro</i> and <i>in Vivo</i>: Regulation of Redox Biology and Mitochondrial Function. Front Aging Neurosci 2018;10:121 Li X et al 2018/01/01 |
Species: Human, Applications: WB | |
| 622 |
Ariazi JL et al. Discovery and Preclinical Characterization of GSK1278863 (Daprodustat), a Small Molecule Hypoxia Inducible Factor-Prolyl Hydroxylase Inhibitor for Anemia. J. Pharmacol. Exp. Ther. 2017 Dec;363(3):336-347 Ariazi JL et al 2017/01/01 |
Species: Human, Applications: WB | |
| 623 |
Wang X et al. Mitochondrial ferritin affects mitochondria by stabilizing HIF-1α in retinal pigment epithelium: implications for the pathophysiology of age-related macular degeneration. Neurobiol. Aging 2016 11;47:168-179 Wang X et al 2016/01/01 |
Applications: WB | |
| 624 |
Zhang D et al. Chemotherapeutic Drug Based Metal-Organic Particles for Microvesicle-Mediated Deep Penetration and Programmable pH/NIR/Hypoxia Activated Cancer Photochemotherapy. Adv Sci (Weinh) 2018 02;5(2):1700648 Zhang D et al 2018/01/01 |
Species: Mouse, Applications: IHC | |
| 625 |
Zheng HL et al. Oligomer procyanidins (F2) repress HIF-1α expression in human U87 glioma cells by inhibiting the EGFR/ AKT/mTOR and MAPK/ERK1/2 signaling pathways <i>in vitro</i> and <i>in vivo</i>. Oncotarget 2017 Oct;8(49):85252-85262 Zheng HL et al 2017/01/01 |
Species: Human, Applications: IHC-P | |
| 626 |
Lee HJ et al. BNIP3 induction by hypoxia stimulates FASN-dependent free fatty acid production enhancing therapeutic potential of umbilical cord blood-derived human mesenchymal stem cells. Redox Biol 2017 10;13:426-443 Lee HJ et al 2017/01/01 |
Species: Human, Applications: WB | |
| 627 |
Li Z et al. Metformin attenuates motility, contraction, and fibrogenic response of hepatic stellate cells <i>in vivo</i> and <i>in vitro</i> by activating AMP-activated protein kinase. World J. Gastroenterol. 2018 Feb;24(7):819-832 Li Z et al 2018/01/01 |
Species: Mouse, Human, Applications: WB | |
| 628 |
Parra V et al. Inhibition of mitochondrial fission prevents hypoxia-induced metabolic shift and cellular proliferation of pulmonary arterial smooth muscle cells. Biochim Biophys Acta Mol Basis Dis 2017 11;1863(11):2891-2903 Parra V et al 2017/01/01 |
Species: Human | |
| 629 |
Lee KH et al. Amyloid β1-42 (Aβ1-42) Induces the CDK2-Mediated Phosphorylation of Tau through the Activation of the mTORC1 Signaling Pathway While Promoting Neuronal Cell Death. Front Mol Neurosci 2017;10:229 Lee KH et al 2017/01/01 |
Species: Human, Applications: WB | |
| 630 |
Hassan A et al. Acute intermittent hypoxia and rehabilitative training following cervical spinal injury alters neuronal hypoxia- and plasticity-associated protein expression. PLoS ONE 2018;13(5):e0197486 Hassan A et al 2018/01/01 |
Species: Rat, Applications: ICC/IF | |
| 631 |
Yoon C et al. Multimodal targeting of tumor vasculature and cancer stem-like cells in sarcomas with VEGF-A inhibition, HIF-1α inhibition, and hypoxia-activated chemotherapy. Oncotarget 2016 Jul;7(28):42844-42858 Yoon C et al 2016/01/01 |
Species: Mouse, Applications: WB | |
| 632 |
Toblli JE et al. Markers of oxidative/nitrosative stress and inflammation in lung tissue of rats exposed to different intravenous iron compounds. Drug Des Devel Ther 2017;11:2251-2263 Toblli JE et al 2017/01/01 |
Species: Rat, Applications: IHC | |
| 633 |
Yaghi L et al. Hypoxia inducible factor-1 mediates the expression of the immune checkpoint HLA-G in glioma cells through hypoxia response element located in exon 2. Oncotarget 2016 Sep;7(39):63690-63707 Yaghi L et al 2016/01/01 |
Species: Human, Applications: ChIP | |
| 634 |
Truong AS et al. Oxygen as a chemoattractant: confirming cellular hypoxia in paper-based invasion assays. Analyst 2016 Jun;141(12):3874-82 Truong AS et al 2016/01/01 |
Species: Human, Applications: ICC/IF | |
| 635 |
Hnatiuk AP et al. Allogeneic Mesenchymal Stromal Cells Overexpressing Mutant Human Hypoxia-Inducible Factor 1-α (HIF1-α) in an Ovine Model of Acute Myocardial Infarction. J Am Heart Assoc 2016 Jul;5(7) Hnatiuk AP et al 2016/01/01 |
Applications: WB | |
| 636 |
Xing Y et al. Fraxinellone has anticancer activity in vivo by inhibiting programmed cell death-ligand 1 expression by reducing hypoxia-inducible factor-1α and STAT3. Pharmacol. Res. 2018 Sep;135:166-180 Xing Y et al 2018/01/01 |
Species: Human, Applications: WB | |
| 637 |
Qing L et al. Expression of hypoxia-inducible factor-1α in synovial fluid and articular cartilage is associated with disease severity in knee osteoarthritis. Exp Ther Med 2017 Jan;13(1):63-68 Qing L et al 2017/01/01 |
Species: Human, Applications: IHC | |
| 638 |
Mi C et al. Imperatorin suppresses proliferation and angiogenesis of human colon cancer cell by targeting HIF-1α via the mTOR/p70S6K/4E-BP1 and MAPK pathways. J Ethnopharmacol 2017 May;203:27-38 Mi C et al 2017/01/01 |
Species: Human, Applications: WB | |
| 639 |
Yang X et al. The hypoxia-inducible factors HIF1α and HIF2α are dispensable for embryonic muscle development but essential for postnatal muscle regeneration. J. Biol. Chem. 2017 04;292(14):5981-5991 Yang X et al 2017/01/01 |
Species: Human, Applications: WB | |
| 640 |
Xu TY et al. Combined use of external therapeutic ultrasound and tirofiban has synergistic therapeutic effects on no-reflow after myocardial reperfusion. Echocardiography 2018 10;35(10):1671-1679 Xu TY et al 2018/01/01 |
Species: Canine, Applications: WB | |
| 641 |
Yamazaki R et al. Antifibrotic effects of cyclosporine A on TGF-β1-treated lung fibroblasts and lungs from bleomycin-treated mice: role of hypoxia-inducible factor-1α. FASEB J. 2017 08;31(8):3359-3371 Yamazaki R et al 2017/01/01 |
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|
| 642 |
Xu F et al. Bisphenol A induces proliferative effects on both breast cancer cells and vascular endothelial cells through a shared GPER-dependent pathway in hypoxia. Environ. Pollut. 2017 Dec;231(Pt 2):1609-1620 Xu F et al 2017/01/01 |
Species: Human, Applications: WB | |
| 643 |
Chung CY et al. Brain-Derived Neurotrophic Factor Loaded PS80 PBCA Nanocarrier for In Vitro Neural Differentiation of Mouse Induced Pluripotent Stem Cells. Int J Mol Sci 2017 Mar;18(3) Chung CY et al 2017/01/01 |
Species: Mouse, Applications: WB | |
| 644 |
Wert KJ et al. Neuroretinal hypoxic signaling in a new preclinical murine model for proliferative diabetic retinopathy. Signal Transduct Target Ther ;1 Wert KJ et al |
Species: Mouse, Applications: WB | |
| 645 |
Li W et al. HIF-2α regulates non-canonical glutamine metabolism via activation of PI3K/mTORC2 pathway in human pancreatic ductal adenocarcinoma. J. Cell. Mol. Med. 2017 Nov;21(11):2896-2908 Li W et al 2017/01/01 |
Species: Human, Applications: WB, IHC | |
| 646 |
Du HC et al. Evaluation of xenogeneic extracellular matrix fabricated from CuCl<sub>2</sub>-conditioned mesenchymal stem cell sheets as a bioactive wound dressing material. J Biomater Appl 2017 Oct;32(4):472-483 Du HC et al 2017/01/01 |
Species: Mouse, Applications: | |
| 647 |
Nishi H et al. Hypoxia inducible factor-1 mediates upregulation of urokinase-type plasminogen activator receptor gene transcription during hypoxia in cervical cancer cells. Oncol. Rep. 2016 Feb;35(2):992-8 Nishi H et al 2016/01/01 |
|
|
| 648 |
Fukushima S et al. Hypoxia-inducible factor 1 alpha is a poor prognostic factor and potential therapeutic target in malignant peripheral nerve sheath tumor. PLoS ONE 2017;12(5):e0178064 Fukushima S et al 2017/01/01 |
Species: Human, Applications: IHC-P | |
| 649 |
Ullah K et al. Hypoxia-inducible factor prolyl-4-hydroxylase-1 is a convergent point in the reciprocal negative regulation of NF-κB and p53 signaling pathways. Sci Rep 2017 Dec;7(1):17220 Ullah K et al 2017/01/01 |
Species: Mouse, Applications: WB | |
| 650 |
Ananthula S et al. Geminin overexpression-dependent recruitment and crosstalk with mesenchymal stem cells enhance aggressiveness in triple negative breast cancers. Oncotarget 2016 Apr;7(15):20869-89 Ananthula S et al 2016/01/01 |
WB | |
| 651 |
Sharpe MA et al. Monoamine oxidase B levels are highly expressed in human gliomas and are correlated with the expression of HiF-1α and with transcription factors Sp1 and Sp3. Oncotarget 2016 Jan;7(3):3379-93 Sharpe MA et al 2016/01/01 |
IHC | |
| 652 |
Zhang X et al. Aging impairs the mobilization and homing of bone marrow-derived angiogenic cells to burn wounds. J. Mol. Med. 2011 Oct;89(10):985-95 Zhang X et al 2011/01/01 |
Species: Mouse, Applications: WB | |
| 653 |
Maugeri G et al. PACAP and VIP Inhibit the Invasiveness of Glioblastoma Cells Exposed to Hypoxia through the Regulation of HIFs and EGFR Expression. Front Pharmacol 2016;7:139 Maugeri G et al 2016/01/01 |
WB | |
| 654 |
Yamano S et al. Role of deltaNp63(pos)CD44v(pos) cells in the development of N-nitroso-tris-chloroethylurea-induced peripheral-type mouse lung squamous cell carcinomas. Cancer Sci. 2016 Feb;107(2):123-32 Yamano S et al 2016/01/01 |
IHC | |
| 655 |
Rizou M et al. The family of 14-3-3 proteins and specifically 14-3-3σ are up-regulated during the development of renal pathologies. J. Cell. Mol. Med. 2018 Sep;22(9):4139-4149 Rizou M et al 2018/01/01 |
Species: Mouse, Applications: ChIP | |
| 656 |
Butt NA et al. Targeting MTA1/HIF-1α signaling by pterostilbene in combination with histone deacetylase inhibitor attenuates prostate cancer progression. Cancer Med 2017 Nov;6(11):2673-2685 Butt NA et al 2017/01/01 |
IHC | |
| 657 |
Takahara Y et al. Deletion of hypoxia-inducible factor-1α in myeloid lineage exaggerates angiotensin II-induced formation of abdominal aortic aneurysm. Clin. Sci. 2017 Apr;131(7):609-620 Takahara Y et al 2017/01/01 |
Species: Mouse, Applications: | |
| 658 |
Kang H et al. Osteoblast Hypoxia-Inducible Factor-1α Pathway Activation Restrains Osteoclastogenesis <i>via</i> the Interleukin-33-MicroRNA-34a-Notch1 Pathway. Front Immunol 2017;8:1312 Kang H et al 2017/01/01 |
Species: Mouse, Applications: WB | |
| 659 |
Gu J et al. Knockdown of HIF-1α by siRNA-expressing plasmid delivered by attenuated Salmonella enhances the antitumor effects of cisplatin on prostate cancer. Sci Rep 2017 Aug;7(1):7546 Gu J et al 2017/01/01 |
Species: Mouse, Applications: WB | |
| 660 |
Heikal L et al. Erythropoietin and a nonerythropoietic peptide analog promote aortic endothelial cell repair under hypoxic conditions: role of nitric oxide. Hypoxia (Auckl) 2016;4:121-133 Heikal L et al 2016/01/01 |
|
|
| 661 |
Pooja et al. Post-translational modifications of eNOS augment nitric oxide availability and facilitates hypoxia adaptation in Ladakhi women. Nitric Oxide 2018 Jun;78:103-112 Pooja et al 2018/01/01 |
Species: Human, Applications: | |
| 662 |
Fujino M et al. Expression of glucose transporter-1 is correlated with hypoxia-inducible factor 1α and malignant potential in pancreatic neuroendocrine tumors. Oncol Lett 2016 Nov;12(5):3337-3343 Fujino M et al 2016/01/01 |
IHC | |
| 663 |
Oh SY et al. Clinicopathologic significance of HIF-1alpha, p53, and VEGF expression and preoperative serum VEGF level in gastric cancer. BMC Cancer 2008 May;8:123 Oh SY et al 2008/01/01 |
Species: Human, Applications: IHC | |
| 664 |
Wang C et al. Highly efficient local delivery of endothelial progenitor cells significantly potentiates angiogenesis and full-thickness wound healing. Acta Biomater 2018 Mar;69:156-169 Wang C et al 2018/01/01 |
Species: Human, Applications: | |
| 665 |
Littlewood-Evans A et al. GPR91 senses extracellular succinate released from inflammatory macrophages and exacerbates rheumatoid arthritis. J. Exp. Med. 2016 08;213(9):1655-62 Littlewood-Evans A et al 2016/01/01 |
Species: Mouse, Applications: WB | |
| 666 |
De Smet S et al. High-intensity interval training in hypoxia does not affect muscle HIF responses to acute hypoxia in humans. Eur. J. Appl. Physiol. 2018 Apr;118(4):847-862 De Smet S et al 2018/01/01 |
Species: Human, Applications: IHC | |
| 667 |
Takasaki C et al. Expression of hypoxia-inducible factor-1α affects tumor proliferation and antiapoptosis in surgically resected lung cancer. Mol Clin Oncol 2016 Aug;5(2):295-300 Takasaki C et al 2016/01/01 |
IHC | |
| 668 |
Li F et al. Enhancement of early cardiac differentiation of dedifferentiated fat cells by dimethyloxalylglycine via notch signaling pathway. Am J Transl Res 2016;8(11):4791-4801 Li F et al 2016/01/01 |
Species: Bovine, Applications: | |
| 669 |
Przygodda F et al. Acute intermittent hypoxia in rats activates muscle proteolytic pathways through a gluccorticoid-dependent mechanism. J. Appl. Physiol. 2017 May;122(5):1114-1124 Przygodda F et al 2017/01/01 |
|
|
| 670 |
Robb KP et al. Inflammation-induced fetal growth restriction in rats is associated with increased placental HIF-1α accumulation. PLoS ONE 2017;12(4):e0175805 Robb KP et al 2017/01/01 |
Species: Rat, Applications: IHC-P | |
| 671 |
Wang E et al. The Role of Factor Inhibiting HIF (FIH-1) in Inhibiting HIF-1 Transcriptional Activity in Glioblastoma Multiforme. PLoS ONE 2014 Jan;9(1):e86102 Wang E et al 2014/01/01 |
Species: Human, Applications: IP, WB | |
| 672 |
Zhang F et al. Impacts of Acute Hypoxia on Alzheimer's Disease-Like Pathologies in APP<sup>swe</sup>/PS1<sup>dE9</sup> Mice and Their Wild Type Littermates. Front Neurosci 2018;12:314 Zhang F et al 2018/01/01 |
Species: Mouse, Applications: WB | |
| 673 |
Suh JH et al. Steroid receptor coactivator-2 (SRC-2) coordinates cardiomyocyte paracrine signaling to promote pressure overload-induced angiogenesis. J. Biol. Chem. 2017 12;292(52):21643-21652 Suh JH et al 2017/01/01 |
Species: Mouse, Applications: | |
| 674 |
Guo L et al. CD163+ macrophages promote angiogenesis and vascular permeability accompanied by inflammation in atherosclerosis. J. Clin. Invest. 2018 Mar;128(3):1106-1124 Guo L et al 2018/01/01 |
Species: Human, Applications: ICC/IF | |
| 675 |
Sch辰fer C et al. Differential Kras<sup>V12</sup> protein levels control a switch regulating lung cancer cell morphology and motility. Converg Sci Phys Oncol 2016 Sep;2(3):035004 Sch辰fer C et al 2016/01/01 |
Species: Human, Applications: IHC-P | |
| 676 |
Oe Y et al. Hepatic dysfunction and thrombocytopenia induced by excess sFlt1 in mice lacking endothelial nitric oxide synthase. Sci Rep 2018 01;8(1):102 Oe Y et al 2018/01/01 |
Species: Human, Applications: IHC | |
| 677 |
Ke S et al. Erythrocytosis in hepatocellular carcinoma portends poor prognosis by respiratory dysfunction secondary to mitochondrial DNA mutations. Hepatology 2017 01;65(1):134-151 Ke S et al 2017/01/01 |
|
|
| 678 |
Lin Z et al. Fatty acid oxidation promotes reprogramming by enhancing oxidative phosphorylation and inhibiting protein kinase C. Stem Cell Res Ther 2018 02;9(1):47 Lin Z et al 2018/01/01 |
Species: Mouse, Applications: WB | |
| 679 |
Carew JS et al. Oncolytic reovirus inhibits angiogenesis through induction of CXCL10/IP-10 and abrogation of HIF activity in soft tissue sarcomas. Oncotarget 2017 Oct;8(49):86769-86783 Carew JS et al 2017/01/01 |
WB | |
| 680 |
Ponente M et al. PML promotes metastasis of triple-negative breast cancer through transcriptional regulation of HIF1A target genes. JCI Insight 2017 Feb;2(4):e87380 Ponente M et al 2017/01/01 |
Species: Human, Applications: ChIP | |
| 681 |
Li HS et al. WITHDRAWN:Mitochondrial targeting of HIF-1α inhibits hypoxia-induced apoptosis independently of its transcriptional activity. Free Radic. Biol. Med. 2018 Apr; Li HS et al 2018/01/01 |
Species: Human, Applications: | |
| 682 |
Chen Y et al. Aerosolized deferoxamine administration in mouse model of bronchopulmonary dysplasia improve pulmonary development. Am J Transl Res 2018;10(1):325-332 Chen Y et al 2018/01/01 |
Species: Mouse, Applications: ICC/IF, WB | |
| 683 |
Mousavizadeh R et al. Angiopoietin-like 4 promotes angiogenesis in the tendon and is increased in cyclically loaded tendon fibroblasts. J. Physiol. (Lond.) 2016 06;594(11):2971-83 Mousavizadeh R et al 2016/01/01 |
WB | |
| 684 |
Liu Y et al. Knockdown of HIF-1α impairs post-ischemic vascular reconstruction in the brain via deficient homing and sprouting bmEPCs. Brain Pathol. 2018 Nov;28(6):860-874 Liu Y et al 2018/01/01 |
Species: Rat, Applications: IHC | |
| 685 |
Serrano-Oviedo L et al. Implication of VHL, ERK5, and HIF-1alpha in clear cell renal cell carcinoma: Molecular basis. Urol. Oncol. 2017 03;35(3):114.e15-114.e22 Serrano-Oviedo L et al 2017/01/01 |
Species: Human, Applications: IHC | |
| 686 |
Koeppen M et al. Hypoxia-inducible factor 2-alpha-dependent induction of amphiregulin dampens myocardial ischemia-reperfusion injury. Nat Commun 2018 02;9(1):816 Koeppen M et al 2018/01/01 |
Species: Mouse, Applications: WB | |
| 687 |
Jacobo-Estrada T et al. Intrauterine Exposure to Cadmium Reduces HIF-1 DNA-Binding Ability in Rat Fetal Kidneys. Toxics 2018 Sep;6(3) Jacobo-Estrada T et al 2018/01/01 |
Species: Rat, Applications: WB | |
| 688 |
Revenco T et al. Low Dose Radiation Causes Skin Cancer in Mice and Has a Differential Effect on Distinct Epidermal Stem Cells. Stem Cells 2017 May;35(5):1355-1364 Revenco T et al 2017/01/01 |
Species: Mouse, Applications: ICC/IF | |
| 689 |
Ma J et al. Zinc finger protein 91 (ZFP91) activates HIF-1α via NF-κB/p65 to promote proliferation and tumorigenesis of colon cancer. Oncotarget 2016 Jun;7(24):36551-36562 Ma J et al 2016/01/01 |
Species: Human, Applications: | |
| 690 |
Olivares-Gonz叩lez L et al. HIF-1α stabilization reduces retinal degeneration in a mouse model of retinitis pigmentosa. FASEB J. 2018 May;32(5):2438-2451 Olivares-Gonz叩lez L et al 2018/01/01 |
Species: Mouse, Applications: | |
| 691 |
Varela-Guruceaga M et al. Effect of hypoxia on caveolae-related protein expression and insulin signaling in adipocytes. Mol. Cell. Endocrinol. 2018 Sep;473:257-267 Varela-Guruceaga M et al 2018/01/01 |
WB | |
| 692 |
Lepp辰nen J et al. Weak HIF-1alpha expression indicates poor prognosis in resectable pancreatic ductal adenocarcinoma. World J Surg Oncol 2018 Jul;16(1):127 Lepp辰nen J et al 2018/01/01 |
Species: Human, Applications: IHC | |
| 693 |
Morita K et al. Relevance of microRNA-18a and microRNA-199a-5p to hepatocellular carcinoma recurrence after living donor liver transplantation. Liver Transpl. 2016 05;22(5):665-76 Morita K et al 2016/01/01 |
|
|
| 694 |
Jeong YJ et al. Correlation of hypoxia inducible transcription factor in breast cancer and SUVmax of F-18 FDG PET/CT. Nucl Med Rev Cent East Eur 2017;20(1):32-38 Jeong YJ et al 2017/01/01 |
Species: Human, Applications: IHC | |
| 695 |
Fujikuni N et al. Hypoxia-mediated CD24 expression is correlated with gastric cancer aggressiveness by promoting cell migration and invasion. Cancer Sci. 2014 Nov;105(11):1411-20 Fujikuni N et al 2014/01/01 |
WB | |
| 696 |
Alhallak K et al. Optical imaging of radiation-induced metabolic changes in radiation-sensitive and resistant cancer cells. J Biomed Opt 2017 06;22(6):60502 Alhallak K et al 2017/01/01 |
Species: Human, Applications: WB | |
| 697 |
Chen H et al. Upregulating Hif-1α by Hydrogel Nanofibrous Scaffolds for Rapidly Recruiting Angiogenesis Relative Cells in Diabetic Wound. Adv Healthc Mater 2016 Apr;5(8):907-18 Chen H et al 2016/01/01 |
|
|
| 698 |
Maugeri G et al. PACAP and VIP Inhibit HIF-1α-Mediated VEGF Expression in a Model of Diabetic Macular Edema. J. Cell. Physiol. 2017 05;232(5):1209-1215 Maugeri G et al 2017/01/01 |
Species: Human, Applications: WB | |
| 699 |
Huang X et al. Folic Acid Represses Hypoxia-Induced Inflammation in THP-1 Cells through Inhibition of the PI3K/Akt/HIF-1α Pathway. PLoS ONE 2016;11(3):e0151553 Huang X et al 2016/01/01 |
|
|
| 700 |
Drareni K et al. GPS2 Deficiency Triggers Maladaptive White Adipose Tissue Expansion in Obesity via HIF1A Activation. Cell Rep 2018 Sep;24(11):2957-2971.e6 Drareni K et al 2018/01/01 |
Species: Mouse, Applications: WB | |
| 701 |
Sobhan PK et al. ASK1 regulates the survival of neuroblastoma cells by interacting with TLX and stabilizing HIF-1α. Cell. Signal. 2017 01;30:104-117 Sobhan PK et al 2017/01/01 |
Species: Mouse, Applications: WB | |
| 702 |
Zhang X et al. Zinc Attenuates Tubulointerstitial Fibrosis in Diabetic Nephropathy Via Inhibition of HIF Through PI-3K Signaling. Biol Trace Elem Res 2016 Oct;173(2):372-83 Zhang X et al 2016/01/01 |
Species: Mouse, Applications: | |
| 703 |
Li H et al. Retinoic acid receptor-related orphan receptor RORα regulates differentiation and survival of keratinocytes during hypoxia. J. Cell. Physiol. 2018 Jan;233(1):641-650 Li H et al 2018/01/01 |
|
|
| 704 |
Miyake T et al. Cold sensitivity of TRPA1 is unveiled by the prolyl hydroxylation blockade-induced sensitization to ROS. Nat Commun 2016 09;7:12840 Miyake T et al 2016/01/01 |
Species: Human, Applications: WB | |
| 705 |
Soncini M et al. 24-Hydroxycholesterol participates in pancreatic neuroendocrine tumor development. Proc. Natl. Acad. Sci. U.S.A. 2016 10;113(41):E6219-E6227 Soncini M et al 2016/01/01 |
Species: Mouse, Applications: ChIP | |
| 706 |
Abu-Remaileh M et al. WWOX controls hepatic HIF1α to suppress hepatocyte proliferation and neoplasia. Cell Death Dis 2018 05;9(5):511 Abu-Remaileh M et al 2018/01/01 |
Species: Mouse, Applications: IHC-P | |
| 707 |
Kowalik MA et al. Metabolic reprogramming identifies the most aggressive lesions at early phases of hepatic carcinogenesis. Oncotarget 2016 May;7(22):32375-93 Kowalik MA et al 2016/01/01 |
Species: Rat, Applications: | |
| 708 |
Judge JL et al. The Lactate Dehydrogenase Inhibitor Gossypol Inhibits Radiation-Induced Pulmonary Fibrosis. Radiat. Res. 2017 07;188(1):35-43 Judge JL et al 2017/01/01 |
Species: Mouse, Applications: IHC | |
| 709 |
Nagamine Y et al. Inhibition of Prolyl Hydroxylase Attenuates Fas Ligand-Induced Apoptosis and Lung Injury in Mice. Am. J. Respir. Cell Mol. Biol. 2016 12;55(6):878-888 Nagamine Y et al 2016/01/01 |
|
|
| 710 |
Waltz PK et al. Heme Oxygenase-2 Localizes to Mitochondria and Regulates Hypoxic Responses in Hepatocytes. Oxid Med Cell Longev 2018;2018:2021645 Waltz PK et al 2018/01/01 |
Species: Mouse, Applications: WB | |
| 711 |
Song Y et al. Hypoxia-induced PLOD2 promotes proliferation, migration and invasion via PI3K/Akt signaling in glioma. Oncotarget 2017 Jun;8(26):41947-41962 Song Y et al 2017/01/01 |
Species: Human, Applications: IHC, WB | |
| 712 |
Lizama-Manibusan BN et al. Analysis of a Nitroreductase-Based Hypoxia Sensor in Primary Neuronal Cultures. ACS Chem Neurosci 2016 09;7(9):1188-91 Lizama-Manibusan BN et al 2016/01/01 |
Species: Rat, Applications: WB | |
| 713 |
Ridiandries A et al. Broad-Spectrum Inhibition of the CC-Chemokine Class Improves Wound Healing and Wound Angiogenesis. Int J Mol Sci 2017 Jan;18(1) Ridiandries A et al 2017/01/01 |
Species: Mouse, Applications: WB | |
| 714 |
Hayashi Y et al. Pathobiological Pseudohypoxia as a Putative Mechanism Underlying Myelodysplastic Syndromes. Cancer Discov 2018 Nov;8(11):1438-1457 Hayashi Y et al 2018/01/01 |
Species: Mouse, Applications: ICC/IF | |
| 715 |
Feng Q et al. A class of extracellular vesicles from breast cancer cells activates VEGF receptors and tumour angiogenesis. Nat Commun 2017 02;8:14450 Feng Q et al 2017/01/01 |
Species: Mouse, Applications: WB | |
| 716 |
Harlander S et al. Combined mutation in Vhl, Trp53 and Rb1 causes clear cell renal cell carcinoma in mice. Nat. Med. 2017 Jul;23(7):869-877 Harlander S et al 2017/01/01 |
Species: Mouse, Applications: IHC-Fr | |
| 717 |
Gon巽alves AF et al. Evidence of renal angiomyolipoma neoplastic stem cells arising from renal epithelial cells. Nat Commun 2017 Nov;8(1):1466 Gon巽alves AF et al 2017/01/01 |
Species: Mouse, Applications: WB | |
| 718 |
Budda SA et al. Transcription Factor HIF-1α Controls Expression of the Cytokine IL-22 in CD4 T Cells. J. Immunol. 2016 10;197(7):2646-52 Budda SA et al 2016/01/01 |
WB | |
| 719 |
Wang J et al. Orai1, 2, 3 and STIM1 promote store-operated calcium entry in pulmonary arterial smooth muscle cells. Cell Death Discov 2017;3:17074 Wang J et al 2017/01/01 |
Species: Mouse, Applications: WB | |
| 720 |
Zhang YT et al. (Z)-ligustilide increases ferroportin1 expression and ferritin content in ischemic SH-SY5Y cells. Eur. J. Pharmacol. 2016 Dec;792:48-53 Zhang YT et al 2016/01/01 |
WB | |
| 721 |
Fraga A et al. Genetic polymorphisms in key hypoxia-regulated downstream molecules and phenotypic correlation in prostate cancer. BMC Urol 2017 Jan;17(1):12 Fraga A et al 2017/01/01 |
|
|
| 722 |
Ridiandries A et al. CC-chemokine class inhibition attenuates pathological angiogenesis while preserving physiological angiogenesis. FASEB J. 2017 03;31(3):1179-1192 Ridiandries A et al 2017/01/01 |
|
|
| 723 |
Cho WK et al. Immunomodulatory effect of captopril and local irradiation on myeloid-derived suppressor cells. Radiat Oncol J 2016 Sep;34(3):223-229 Cho WK et al 2016/01/01 |
IHC-P | |
| 724 |
Choi YK et al. Dual effects of carbon monoxide on pericytes and neurogenesis in traumatic brain injury. Nat. Med. 2016 Nov;22(11):1335-1341 Choi YK et al 2016/01/01 |
Species: Mouse, Applications: IHC | |
| 725 |
Shih JW et al. Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1α co-activator driving oral cancer progression. Nat Commun 2017 06;8:15874 Shih JW et al 2017/01/01 |
Species: Human, Applications: IP | |
| 726 |
Maugeri G et al. Nicotine promotes blood retinal barrier damage in a model of human diabetic macular edema. Toxicol In Vitro 2017 Oct;44:182-189 Maugeri G et al 2017/01/01 |
Species: Human, Applications: | |
| 727 |
Liu Y et al. Follistatin-like protein 1 plays a tumor suppressor role in clear-cell renal cell carcinoma. Chin J Cancer 2018 Jan;37(1):2 Liu Y et al 2018/01/01 |
Species: Human, Applications: IHC-P | |
| 728 |
Tan JT et al. High-Density Lipoproteins Rescue Diabetes-Impaired Angiogenesis via Scavenger Receptor Class B Type I. Diabetes 2016 10;65(10):3091-103 Tan JT et al 2016/01/01 |
|
|
| 729 |
Ichimaru S et al. Hypoxia Potentiates Anabolic Effects of Exogenous Hyaluronic Acid in Rat Articular Cartilage. Int J Mol Sci 2016 Jun;17(7) Ichimaru S et al 2016/01/01 |
WB | |
| 730 |
Park SJ et al. Estradiol, TGF-β1 and hypoxia promote breast cancer stemness and EMT-mediated breast cancer migration. Oncol Lett 2016 Mar;11(3):1895-1902 Park SJ et al 2016/01/01 |
WB | |
| 731 |
Sreekumar PG et al. Regulation of thioredoxin by ceramide in retinal pigment epithelial cells. Exp. Eye Res. 2009 Mar;88(3):410-7 Sreekumar PG et al 2009/01/01 |
Species: Human, Applications: WB | |
| 732 |
Wu XM et al. Bi-directionally protective communication between neurons and astrocytes under ischemia. Redox Biol 2017 10;13:20-31 Wu XM et al 2017/01/01 |
Species: Rat, Applications: WB | |
| 733 |
Kubo H et al. Regulation and clinical significance of the hypoxia-induced expression of ANGPTL4 in gastric cancer. Oncol Lett 2016 Feb;11(2):1026-1034 Kubo H et al 2016/01/01 |
WB | |
| 734 |
An YA et al. Angiopoietin-2 in white adipose tissue improves metabolic homeostasis through enhanced angiogenesis. Elife 2017 03;6 An YA et al 2017/01/01 |
|
|
| 735 |
Wang H et al. NDRG1 inhibition sensitizes osteosarcoma cells to combretastatin A-4 through targeting autophagy. Cell Death Dis 2017 09;8(9):e3048 Wang H et al 2017/01/01 |
Species: Human, Applications: | |
| 736 |
Frey JL et al. Hypoxia-inducible factor-1α restricts the anabolic actions of parathyroid hormone. Bone Res 2014;2:14005 Frey JL et al 2014/01/01 |
IP | |
| 737 |
Mongiardi MP et al. c-MYC inhibition impairs hypoxia response in glioblastoma multiforme. Oncotarget 2016 May;7(22):33257-71 Mongiardi MP et al 2016/01/01 |
Species: Human, Applications: | |
| 738 |
Krishnamachary B et al. Hypoxia-Induced Reporter Genes with Different Half-Lives. Methods Mol. Biol. 2018;1790:113-125 Krishnamachary B et al 2018/01/01 |
Species: Human, Applications: WB | |
| 739 |
Wendeln AC et al. Innate immune memory in the brain shapes neurological disease hallmarks. Nature 2018 04;556(7701):332-338 Wendeln AC et al 2018/01/01 |
Species: Mouse, Applications: | |
| 740 |
Yamaleyeva LM et al. Photoacoustic imaging for <i>in vivo</i> quantification of placental oxygenation in mice. FASEB J. 2017 12;31(12):5520-5529 Yamaleyeva LM et al 2017/01/01 |
Species: Mouse, Applications: | |
| 741 |
Matsuyama T et al. Expression of hypoxia-inducible factor-1alpha in esophageal squamous cell carcinoma. Cancer Sci. 2005 Mar;96(3):176-82 Matsuyama T et al 2005/01/01 |
|
|
| 742 |
Shimauchi T et al. TRPC3-Nox2 complex mediates doxorubicin-induced myocardial atrophy. JCI Insight 2017 Aug;2(15) Shimauchi T et al 2017/01/01 |
Species: Mouse, Applications: WB | |
| 743 |
Fujimoto Y et al. Low Cardiac Output Leads Hepatic Fibrosis in Right Heart Failure Model Rats. PLoS ONE 2016;11(2):e0148666 Fujimoto Y et al 2016/01/01 |
WB | |
| 744 |
Chen R et al. High mobility group protein B1 controls liver cancer initiation through yes-associated protein -dependent aerobic glycolysis. Hepatology 2018 May;67(5):1823-1841 Chen R et al 2018/01/01 |
Species: Mouse, Applications: | |
| 745 |
Gagner JP et al. Induction and Assessment of Hypoxia in Glioblastoma Cells In Vitro. Methods Mol. Biol. 2018;1741:111-123 Gagner JP et al 2018/01/01 |
WB | |
| 746 |
Abu-Remaileh M et al. Tumor suppressor WWOX regulates glucose metabolism via HIF1α modulation. Cell Death Differ. 2014 Nov;21(11):1805-14 Abu-Remaileh M et al 2014/01/01 |
WB | |
| 747 |
Lehmann H et al. Combined Deletion of Vhl and Kif3a Accelerates Renal Cyst Formation. J. Am. Soc. Nephrol. 2015 Nov;26(11):2778-88 Lehmann H et al 2015/01/01 |
|
|
| 748 |
Li L et al. Transcriptional Regulation of the Warburg Effect in Cancer by SIX1. Cancer Cell 2018 Mar;33(3):368-385.e7 Li L et al 2018/01/01 |
Species: Human, Applications: | |
| 749 |
Chen W et al. Targeting renal cell carcinoma with a HIF-2 antagonist. Nature 2016 11;539(7627):112-117 Chen W et al 2016/01/01 |
Species: Human, Applications: PLA | |
| 750 |
Zhu W et al. Daam2 driven degradation of VHL promotes gliomagenesis. Elife 2017 10;6 Zhu W et al 2017/01/01 |
Species: Mouse, Applications: WB | |
| 751 |
Masuelli L et al. Chloroquine supplementation increases the cytotoxic effect of curcumin against Her2/neu overexpressing breast cancer cells <i>in vitro</i> and <i>in vivo</i> in nude mice while counteracts it in immune competent mice. Oncoimmunology ;6(1 Masuelli L et al |
|
|
| 752 |
Shuck SC et al. Metal-Assisted Protein Quantitation (MAPq): Multiplex Analysis of Protein Expression Using Lanthanide-Modified Antibodies with Detection by Inductively Coupled Plasma Mass Spectrometry. Anal Chem 2020 06;92(11):7556-7564 Shuck SC et al 2020/01/01 |
|
|
| 753 |
Wang Z et al. Hypoxia Protects Rat Bone Marrow Mesenchymal Stem Cells Against Compression-Induced Apoptosis in the Degenerative Disc Microenvironment Through Activation of the HIF-1α/YAP Signaling Pathway. Stem Cells Dev 2020 10;29(20):1309-1319 Wang Z et al 2020/01/01 |
|
|
| 754 |
Singh SK et al. Hypoxia-inducible factor-1α induces CX3CR1 expression and promotes the epithelial to mesenchymal transition (EMT) in ovarian cancer cells. J Ovarian Res 2019 May;12(1):42 Singh SK et al 2019/01/01 |
|
|
| 755 |
Fang X et al. Dishevelled Associated Activator Of Morphogenesis (DAAM) Facilitates Invasion of Hepatocellular Carcinoma by Upregulating Hypoxia-Inducible Factor 1α (HIF-1α) Expression. Med Sci Monit 2020 Aug;26:e924670 Fang X et al 2020/01/01 |
|
|
| 756 |
Courtney KD et al. HIF-2 Complex Dissociation, Target Inhibition, and Acquired Resistance with PT2385, a First-in-Class HIF-2 Inhibitor, in Patients with Clear Cell Renal Cell Carcinoma. Clin Cancer Res 2020 02;26(4):793-803 Courtney KD et al 2020/01/01 |
|
|
| 757 |
Qi D et al. Hypoxia inducible factor 1α in vascular smooth muscle cells promotes angiotensin II-induced vascular remodeling via activation of CCL7-mediated macrophage recruitment. Cell Death Dis 2019 07;10(8):544 Qi D et al 2019/01/01 |
|
|
| 758 |
Ben-Aicha S et al. High-density lipoprotein remodelled in hypercholesterolaemic blood induce epigenetically driven down-regulation of endothelial HIF-1α expression in a preclinical animal model. Cardiovasc Res 2020 06;116(7):1288-1299 Ben-Aicha S et al 2020/01/01 |
|
|
| 759 |
Gangwar A et al. Intermittent hypoxia modulates redox homeostasis, lipid metabolism associated inflammatory processes and redox post-translational modifications: Benefits at high altitude. Sci Rep 2020 05;10(1):7899 Gangwar A et al 2020/01/01 |
|
|
| 760 |
Karuppagounder SS et al. Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models. Sci Transl Med 2016 Mar;8(328):328ra29 Karuppagounder SS et al 2016/01/01 |
|
|
| 761 |
Fujii T et al. Enhanced HIF2α expression during human trophoblast differentiation into syncytiotrophoblast suppresses transcription of placental growth factor. Sci Rep 2017 09;7(1):12455 Fujii T et al 2017/01/01 |
|
|
| 762 |
Kang YBA et al. Progressive hypoxia-on-a-chip: An in vitro oxygen gradient model for capturing the effects of hypoxia on primary hepatocytes in health and disease. Biotechnol Bioeng 2020 03;117(3):763-775 Kang YBA et al 2020/01/01 |
|
|
| 763 |
Xiong Z et al. Correlation between the HIF-1α/Notch signaling pathway and Modic changes in nucleus pulposus cells isolated from patients with low back pain. BMC Musculoskelet Disord 2020 Jul;21(1):500 Xiong Z et al 2020/01/01 |
|
|
| 764 |
Roudkenar MH et al. Disturbance in the regulation of miR 17-92 cluster on HIF-1-α expression contributes to clinically relevant radioresistant cells: an in vitro study. Cytotechnology 2020 Feb;72(1):141-153 Roudkenar MH et al 2020/01/01 |
|
|
| 765 |
Lange CAK et al. Increased expression of hypoxia-inducible factor-1 alpha and its impact on transcriptional changes and prognosis in malignant tumours of the ocular adnexa. Eye (Lond) 2018 11;32(11):1772-1782 Lange CAK et al 2018/01/01 |
|
|
| 766 |
Wang Y et al. Blood Oxygen Level-Dependent Imaging and Intravoxel Incoherent Motion MRI of Early Contrast-Induced Acute Kidney Injury in a Rabbit Model. Kidney Blood Press Res 2019;44(4):496-512 Wang Y et al 2019/01/01 |
|
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| 767 |
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Tang SY et al. Caspr1 Facilitates sAPPα Production by Regulating α-Secretase ADAM9 in Brain Endothelial Cells. Front Mol Neurosci 2020;13:23 Tang SY et al 2020/01/01 |
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Aguanno S et al. A Three-Dimensional Culture Model of Reversibly Quiescent Myogenic Cells. Stem Cells Int 2019;2019:7548160 Aguanno S et al 2019/01/01 |
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Chen YL et al. MicroRNA-214 modulates the senescence of vascular smooth muscle cells in carotid artery stenosis. Mol Med 2020 05;26(1):46 Chen YL et al 2020/01/01 |
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Wu JY et al. Cancer-Derived Succinate Promotes Macrophage Polarization and Cancer Metastasis via Succinate Receptor. Mol Cell 2020 01;77(2):213-227.e5 Wu JY et al 2020/01/01 |
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Romeo-Guitart D et al. Improved Motor Nerve Regeneration by SIRT1/Hif1a-Mediated Autophagy. Cells 2019 10;8(11) Romeo-Guitart D et al 2019/01/01 |
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Dong Z et al. Histone hyperacetylation mediates enhanced IL-1β production in LPS/IFN-γ-stimulated macrophages. Immunology 2020 06;160(2):183-197 Dong Z et al 2020/01/01 |
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Kim S et al. Effects of empagliflozin on nondiabetic salt-sensitive hypertension in uninephrectomized rats. Hypertens Res 2019 12;42(12):1905-1915 Kim S et al 2019/01/01 |
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Bommi PV et al. NER-factor DDB2 regulates HIF1α and hypoxia-response genes in HNSCC. Oncogene 2020 02;39(8):1784-1796 Bommi PV et al 2020/01/01 |
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Su CC et al. Effects of antibodies against human parvovirus B19 on angiogenic signaling. Mol Med Rep 2020 Mar;21(3):1320-1327 Su CC et al 2020/01/01 |
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Paul S et al. Modulation of lung cytoskeletal remodeling, RXR based metabolic cascades and inflammation to achieve redox homeostasis during extended exposures to lowered pO<sub>2</sub>. Apoptosis 2021 Aug;26(7-8):431-446 Paul S et al 2021/01/01 |
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Wang C et al. Hyperbaric Oxygen Improves Cerebral Ischemia/Reperfusion Injury in Rats Probably via Inhibition of Autophagy Triggered by the Downregulation of Hypoxia-Inducing Factor-1 Alpha. Biomed Res Int 2021;2021:6615685 Wang C et al 2021/01/01 |
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Aarup A et al. Hypoxia-Inducible Factor-1α Expression in Macrophages Promotes Development of Atherosclerosis. Arterioscler Thromb Vasc Biol 2016 09;36(9):1782-90 Aarup A et al 2016/01/01 |
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Wan X et al. Hypoxia-preconditioned adipose-derived stem cells combined with scaffold promote urethral reconstruction by upregulation of angiogenesis and glycolysis. Stem Cell Res Ther 2020 12;11(1):535 Wan X et al 2020/01/01 |
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Beppu T et al. High-uptake areas on positron emission tomography with the hypoxic radiotracer (18)F-FRP170 in glioblastomas include regions retaining proliferative activity under hypoxia. Ann Nucl Med 2015 May;29(4):336-41 Beppu T et al 2015/01/01 |
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Xie H et al. hCINAP serves a critical role in hypoxia‑induced cardiomyocyte apoptosis via modulating lactate production and mitochondrial‑mediated apoptosis signaling. Mol Med Rep 2021 02;23(2) Xie H et al 2021/01/01 |
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Paul S et al. D4F prophylaxis enables redox and energy homeostasis while preventing inflammation during hypoxia exposure. Biomed Pharmacother 2021 Jan;133:111083 Paul S et al 2021/01/01 |
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Favara DM et al. Elevated expression of the adhesion GPCR ADGRL4/ELTD1 promotes endothelial sprouting angiogenesis without activating canonical GPCR signalling. Sci Rep 2021 Apr;11(1):8870 Favara DM et al 2021/01/01 |
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Fan T et al. Arsenic Dispensing Powder Promotes Erythropoiesis in Myelodysplastic Syndromes via Downregulation of HIF1A and Upregulation of GATA Factors. Am J Chin Med 2021;49(2):461-485 Fan T et al 2021/01/01 |
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Zheng J et al. TRIM21 drives intervertebral disc degeneration induced by oxidative stress via mediating HIF-1α degradation. Biochem Biophys Res Commun 2021 05;555:46-53 Zheng J et al 2021/01/01 |
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Cerniglia GJ et al. Epidermal growth factor receptor inhibition modulates the microenvironment by vascular normalization to improve chemotherapy and radiotherapy efficacy. PLoS One 2009 Aug;4(8):e6539 Cerniglia GJ et al 2009/01/01 |
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Wang M et al. An Ultra-Stable, Oxygen-Supply Nanoprobe Emitting in Near-Infrared-II Window to Guide and Enhance Radiotherapy by Promoting Anti-Tumor Immunity. Adv Healthc Mater 2021 06;10(12):e2100090 Wang M et al 2021/01/01 |
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H旦per T et al. The Contact Allergen NiSO<sub>4</sub> Triggers a Distinct Molecular Response in Primary Human Dendritic Cells Compared to Bacterial LPS. Front Immunol 2021;12:644700 H旦per T et al 2021/01/01 |
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Hagisawa K et al. Intraosseous transfusion of hemoglobin vesicles in the treatment of hemorrhagic shock with collapsed vessels in a rabbit model. Transfusion 2020 07;60(7):1400-1409 Hagisawa K et al 2020/01/01 |
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Zeng J et al. CD46 splice variant enhances translation of specific mRNAs linked to an aggressive tumor cell phenotype in bladder cancer. Mol Ther Nucleic Acids 2021 Jun;24:140-153 Zeng J et al 2021/01/01 |
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Shang FF et al. Design, synthesis of novel celastrol derivatives and study on their antitumor growth through HIF-1α pathway. Eur J Med Chem 2021 Aug;220:113474 Shang FF et al 2021/01/01 |
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de Laia AGS et al. Cobalt-containing bioactive glass mimics vascular endothelial growth factor A and hypoxia inducible factor 1 function. J Biomed Mater Res A 2021 07;109(7):1051-1064 de Laia AGS et al 2021/01/01 |
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Toth RK et al. Hypoxia-induced PIM kinase and laminin-activated integrin α6 mediate resistance to PI3K inhibitors in bone-metastatic CRPC. Am J Clin Exp Urol 2019;7(4):297-312 Toth RK et al 2019/01/01 |
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Zheng J et al. GLP-1 improves the supportive ability of astrocytes to neurons by promoting aerobic glycolysis in Alzheimer's disease. Mol Metab 2021 05;47:101180 Zheng J et al 2021/01/01 |
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Docherty CK et al. Influence of 2-Methoxyestradiol and Sex on Hypoxia-Induced Pulmonary Hypertension and Hypoxia-Inducible Factor-1-α. J Am Heart Assoc 2019 03;8(5):e011628 Docherty CK et al 2019/01/01 |
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Sakai T et al. Development of antitumor biguanides targeting energy metabolism and stress responses in the tumor microenvironment. Sci Rep 2021 Mar;11(1):4852 Sakai T et al 2021/01/01 |
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Penny HL et al. Targeting Glycolysis in Macrophages Confers Protection Against Pancreatic Ductal Adenocarcinoma. Int J Mol Sci 2021 Jun;22(12) Penny HL et al 2021/01/01 |
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De Ponti C et al. Adenosine A2a receptor-mediated, normoxic induction of HIF-1 through PKC and PI-3K-dependent pathways in macrophages. J Leukoc Biol 2007 Aug;82(2):392-402 De Ponti C et al 2007/01/01 |
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S叩nchez-Del-Campo L et al. MITF induces escape from innate immunity in melanoma. J Exp Clin Cancer Res 2021 Mar;40(1):117 S叩nchez-Del-Campo L et al 2021/01/01 |
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He R et al. HIF1A Alleviates compression-induced apoptosis of nucleus pulposus derived stem cells via upregulating autophagy. Autophagy 2021 Jan;:1-23 He R et al 2021/01/01 |
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Gong R et al. A Comparison of Subconjunctival Wound Healing between Different Methods of Dissecting Subconjunctival Tissues. Ophthalmic Res 2021;64(1):99-107 Gong R et al 2021/01/01 |
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Baumeister J et al. Hypoxia-inducible factor 1 (HIF-1) is a new therapeutic target in JAK2V617F-positive myeloproliferative neoplasms. Leukemia 2020 04;34(4):1062-1074 Baumeister J et al 2020/01/01 |
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Zheng H et al. HIF1α promotes tumor chemoresistance via recruiting GDF15-producing TAMs in colorectal cancer. Exp Cell Res 2021 01;398(2):112394 Zheng H et al 2021/01/01 |
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| 855 |
Shi Y et al. Phosphorylation of seryl-tRNA synthetase by ATM/ATR is essential for hypoxia-induced angiogenesis. PLoS Biol 2020 12;18(12):e3000991 Shi Y et al 2020/01/01 |
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| 856 |
Gauthier LR et al. The HIF1α/JMY pathway promotes glioblastoma stem-like cell invasiveness after irradiation. Sci Rep 2020 10;10(1):18742 Gauthier LR et al 2020/01/01 |
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| 857 |
Moon Y et al. Hypoxia regulates allele-specific histone modification of the imprinted H19 gene. Biochim Biophys Acta Gene Regul Mech 2020 11;1863(11):194643 Moon Y et al 2020/01/01 |
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| 858 |
Song Y et al. Involvement of impaired autophagy and mitophagy in Neuro-2a cell damage under hypoxic and/or high-glucose conditions. Sci Rep 2018 02;8(1):3301 Song Y et al 2018/01/01 |
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| 859 |
Baglieri J et al. Nondegradable Collagen Increases Liver Fibrosis but Not Hepatocellular Carcinoma in Mice. Am J Pathol 2021 09;191(9):1564-1579 Baglieri J et al 2021/01/01 |
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Imai T et al. Hypoxia attenuates the expression of E-cadherin via up-regulation of SNAIL in ovarian carcinoma cells. Am J Pathol 2003 Oct;163(4):1437-47 Imai T et al 2003/01/01 |
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Yao X et al. Neuroprotective and Angiogenesis Effects of Levetiracetam Following Ischemic Stroke in Rats. Front Pharmacol 2021;12:638209 Yao X et al 2021/01/01 |
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| 862 |
David BT et al. Treatment with hypoxia-mimetics protects cultured rat Schwann cells against oxidative stress-induced cell death. Glia 2021 Sep;69(9):2215-2234 David BT et al 2021/01/01 |
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| 863 |
Xiao Q et al. A p53-based genetic tracing system to follow postnatal cardiomyocyte expansion in heart regeneration. Development 2017 02;144(4):580-589 Xiao Q et al 2017/01/01 |
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| 864 |
Wang C et al. Protective effect of nicorandil on collapse‑induced lung injury in rabbits by inhibiting apoptosis. Int J Mol Med 2019 Aug;44(2):725-736 Wang C et al 2019/01/01 |
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Singh A et al. Characterizing Ischaemic Tolerance in Rat Pheochromocytoma (PC12) Cells and Primary Rat Neurons. Neuroscience 2021 01;453:17-31 Singh A et al 2021/01/01 |
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| 866 |
Wang B et al. Magnetic resonance diffusion tensor imaging applied to rat model of contrast-induced acute kidney injury. PeerJ 2021;9:e10620 Wang B et al 2021/01/01 |
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| 867 |
Kuwano A et al. Microcirculatory disturbance in acute liver injury. Exp Ther Med 2021 Jun;21(6):596 Kuwano A et al 2021/01/01 |
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Hirayama Y et al. Mechanisms underlying sensitization of P2X7 receptors in astrocytes for induction of ischemic tolerance. Glia 2021 Sep;69(9):2100-2110 Hirayama Y et al 2021/01/01 |
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Dong W et al. Adipose-Derived Stem Cells Based on Electrospun Biomimetic Scaffold Mediated Endothelial Differentiation Facilitating Regeneration and Repair of Abdominal Wall Defects <i>via</i> HIF-1α/VEGF Pathway. Front Bioeng Biotechnol 2021;9:6764 Dong W et al 2021/01/01 |
Applications: ICC/IF | |
| 870 |
Wang Y et al. PTEN protects kidney against acute kidney injury by alleviating apoptosis and promoting autophagy via regulating HIF1-α and mTOR through PI3K/Akt pathway. Exp Cell Res 2021 09;406(1):112729 Wang Y et al 2021/01/01 |
Applications: WB | |
| 871 |
Zhou F et al. Si-Wu-Tang facilitates ovarian function through improving ovarian microenvironment and angiogenesis in a mouse model of premature ovarian failure. J Ethnopharmacol 2021 Nov;280:114431 Zhou F et al 2021/01/01 |
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| 872 |
Nakahara M et al. The inflammatory role of dysregulated IRS2 in pulmonary vascular remodeling under hypoxic conditions. Am J Physiol Lung Cell Mol Physiol 2021 08;321(2):L416-L428 Nakahara M et al 2021/01/01 |
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| 873 |
Chen MH et al. HIF-1α activator DMOG inhibits alveolar bone resorption in murine periodontitis by regulating macrophage polarization. Int Immunopharmacol 2021 Oct;99:107901 Chen MH et al 2021/01/01 |
Applications: IHC | |
| 874 |
Yu S et al. Tumor-derived LIF promotes chemoresistance via activating tumor-associated macrophages in gastric cancers. Exp Cell Res 2021 09;406(1):112734 Yu S et al 2021/01/01 |
Applications: WB, ChIP | |
| 875 |
Kuo MC et al. Hypoxia-Induced Epithelial-to-Mesenchymal Transition in Proximal Tubular Epithelial Cells through miR-545-3p-TNFSF10. Biomolecules 2021 07;11(7) Kuo MC et al 2021/01/01 |
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| 876 |
Ciminera AK et al. Elevated glucose increases genomic instability by inhibiting nucleotide excision repair. Life Sci Alliance 2021 10;4(10) Ciminera AK et al 2021/01/01 |
Species: Human, Applications: WB | |
| 877 |
Li Y et al. Insulin signaling establishes a developmental trajectory of adipose regulatory T cells. Nat Immunol 2021 09;22(9):1175-1185 Li Y et al 2021/01/01 |
Species: Mouse, Applications: ChIP | |
| 878 |
Kumar Singh R et al. KSHV-encoded vCyclin can modulate HIF1α levels to promote DNA replication in hypoxia. Elife 2021 07;10 Kumar Singh R et al 2021/01/01 |
Applications: WB, ICC/IF | |
| 879 |
Guo XH et al. The locoregional adiponectin and its synergistic antitumor effect with HIF-1α blockade in TSCC. Oral Dis 2021 Jun; Guo XH et al 2021/01/01 |
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Park H et al. 3,3'-Diindolylmethane inhibits VEGF expression through the HIF-1α and NF-κB pathways in human retinal pigment epithelial cells under chemical hypoxic conditions. Int. J. Mol. Med. 2015 Jul;36(1):301-8
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Kumar P et al. Estrogen-related receptor gamma (ERRgamma) mediates oxygen-dependent induction of aromatase (CYP19) gene expression during human trophoblast differentiation. Mol. Endocrinol. 2011 Sep;25(9):1513-26
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Joo HY et al. SIRT1 deacetylates and stabilizes hypoxia-inducible factor-1α (HIF-1α) via direct interactions during hypoxia. Biochem. Biophys. Res. Commun. 2015 Jul;462(4):294-300
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参照：
- No.： 859
-
文献情報：
Baglieri J et al. Nondegradable Collagen Increases Liver Fibrosis but Not Hepatocellular Carcinoma in Mice. Am J Pathol 2021 09;191(9):1564-1579
Baglieri J et al
2021/01/01
-
備考：
-
参照：
- No.： 860
-
文献情報：
Imai T et al. Hypoxia attenuates the expression of E-cadherin via up-regulation of SNAIL in ovarian carcinoma cells. Am J Pathol 2003 Oct;163(4):1437-47
Imai T et al
2003/01/01
-
備考：
-
参照：
- No.： 861
-
文献情報：
Yao X et al. Neuroprotective and Angiogenesis Effects of Levetiracetam Following Ischemic Stroke in Rats. Front Pharmacol 2021;12:638209
Yao X et al
2021/01/01
-
備考：
-
参照：
- No.： 862
-
文献情報：
David BT et al. Treatment with hypoxia-mimetics protects cultured rat Schwann cells against oxidative stress-induced cell death. Glia 2021 Sep;69(9):2215-2234
David BT et al
2021/01/01
-
備考：
-
参照：
- No.： 863
-
文献情報：
Xiao Q et al. A p53-based genetic tracing system to follow postnatal cardiomyocyte expansion in heart regeneration. Development 2017 02;144(4):580-589
Xiao Q et al
2017/01/01
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備考：
-
参照：
- No.： 864
-
文献情報：
Wang C et al. Protective effect of nicorandil on collapse‑induced lung injury in rabbits by inhibiting apoptosis. Int J Mol Med 2019 Aug;44(2):725-736
Wang C et al
2019/01/01
-
備考：
-
参照：
- No.： 865
-
文献情報：
Singh A et al. Characterizing Ischaemic Tolerance in Rat Pheochromocytoma (PC12) Cells and Primary Rat Neurons. Neuroscience 2021 01;453:17-31
Singh A et al
2021/01/01
-
備考：
-
参照：
- No.： 866
-
文献情報：
Wang B et al. Magnetic resonance diffusion tensor imaging applied to rat model of contrast-induced acute kidney injury. PeerJ 2021;9:e10620
Wang B et al
2021/01/01
-
備考：
-
参照：
- No.： 867
-
文献情報：
Kuwano A et al. Microcirculatory disturbance in acute liver injury. Exp Ther Med 2021 Jun;21(6):596
Kuwano A et al
2021/01/01
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備考：
-
参照：
- No.： 868
-
文献情報：
Hirayama Y et al. Mechanisms underlying sensitization of P2X7 receptors in astrocytes for induction of ischemic tolerance. Glia 2021 Sep;69(9):2100-2110
Hirayama Y et al
2021/01/01
-
備考：
-
参照：
- No.： 869
-
文献情報：
Dong W et al. Adipose-Derived Stem Cells Based on Electrospun Biomimetic Scaffold Mediated Endothelial Differentiation Facilitating Regeneration and Repair of Abdominal Wall Defects <i>via</i> HIF-1α/VEGF Pathway. Front Bioeng Biotechnol 2021;9:6764
Dong W et al
2021/01/01
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備考：
Applications: ICC/IF -
参照：
- No.： 870
-
文献情報：
Wang Y et al. PTEN protects kidney against acute kidney injury by alleviating apoptosis and promoting autophagy via regulating HIF1-α and mTOR through PI3K/Akt pathway. Exp Cell Res 2021 09;406(1):112729
Wang Y et al
2021/01/01
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備考：
Applications: WB -
参照：
- No.： 871
-
文献情報：
Zhou F et al. Si-Wu-Tang facilitates ovarian function through improving ovarian microenvironment and angiogenesis in a mouse model of premature ovarian failure. J Ethnopharmacol 2021 Nov;280:114431
Zhou F et al
2021/01/01
-
備考：
Applications: WB -
参照：
- No.： 872
-
文献情報：
Nakahara M et al. The inflammatory role of dysregulated IRS2 in pulmonary vascular remodeling under hypoxic conditions. Am J Physiol Lung Cell Mol Physiol 2021 08;321(2):L416-L428
Nakahara M et al
2021/01/01
-
備考：
-
参照：
- No.： 873
-
文献情報：
Chen MH et al. HIF-1α activator DMOG inhibits alveolar bone resorption in murine periodontitis by regulating macrophage polarization. Int Immunopharmacol 2021 Oct;99:107901
Chen MH et al
2021/01/01
-
備考：
Applications: IHC -
参照：
- No.： 874
-
文献情報：
Yu S et al. Tumor-derived LIF promotes chemoresistance via activating tumor-associated macrophages in gastric cancers. Exp Cell Res 2021 09;406(1):112734
Yu S et al
2021/01/01
-
備考：
Applications: WB, ChIP -
参照：
- No.： 875
-
文献情報：
Kuo MC et al. Hypoxia-Induced Epithelial-to-Mesenchymal Transition in Proximal Tubular Epithelial Cells through miR-545-3p-TNFSF10. Biomolecules 2021 07;11(7)
Kuo MC et al
2021/01/01
-
備考：
Applications: WB -
参照：
- No.： 876
-
文献情報：
Ciminera AK et al. Elevated glucose increases genomic instability by inhibiting nucleotide excision repair. Life Sci Alliance 2021 10;4(10)
Ciminera AK et al
2021/01/01
-
備考：
Species: Human, Applications: WB -
参照：
- No.： 877
-
文献情報：
Li Y et al. Insulin signaling establishes a developmental trajectory of adipose regulatory T cells. Nat Immunol 2021 09;22(9):1175-1185
Li Y et al
2021/01/01
-
備考：
Species: Mouse, Applications: ChIP -
参照：
- No.： 878
-
文献情報：
Kumar Singh R et al. KSHV-encoded vCyclin can modulate HIF1α levels to promote DNA replication in hypoxia. Elife 2021 07;10
Kumar Singh R et al
2021/01/01
-
備考：
Applications: WB, ICC/IF -
参照：
- No.： 879
-
文献情報：
Guo XH et al. The locoregional adiponectin and its synergistic antitumor effect with HIF-1α blockade in TSCC. Oral Dis 2021 Jun;
Guo XH et al
2021/01/01
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備考：
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参照：