Anti-IKK alpha - Azide Free, Mouse-Mono(14A231)

データシート

• 商品コード：NBP2-27409
• メーカー：NOV
• 包装：0.1mg
• 価格： ¥108,000
• 在庫：無(未発注)

マイリストに追加 マイリストに追加済

• No.： 1
• 文献情報：
  Vinolo E et al. A point mutation in NEMO associated with anhidrotic ectodermal dysplasia with immunodeficiency pathology results in destabilization of the oligomer and reduces lipopolysaccharide- and tumor necrosis factor-mediated NF-kappa B activation. J
  Vinolo E et al
  2006/01/01
  
• 備考：
  
• 参照：
  

• No.： 2
• 文献情報：
  Shishodia S et al. Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates TNF-induced NF-kappa B activation through inhibition of activation of I kappa B alpha kinase and Akt in human non-small cell lung carcinoma: correlation with suppression of COX-2 synt
  Shishodia S et al
  2004/01/01
  
• 備考：
  
• 参照：
  

• No.： 3
• 文献情報：
  Takada Y et al. Flavopiridol inhibits NF-kappaB activation induced by various carcinogens and inflammatory agents through inhibition of IkappaBalpha kinase and p65 phosphorylation: abrogation of cyclin D1, cyclooxygenase-2, and matrix metalloprotease-9. J
  Takada Y et al
  2004/01/01
  
• 備考：
  
• 参照：
  

• No.： 4
• 文献情報：
  Panopoulos A et al. Iron-mediated H2O2 production as a mechanism for cell type-specific inhibition of tumor necrosis factor alpha-induced but not interleukin-1beta-induced IkappaB kinase complex/nuclear factor-kappaB activation. J. Biol. Chem. 2005 Jan;28
  Panopoulos A et al
  2005/01/01
  
• 備考：
  
• 参照：
  

• No.： 5
• 文献情報：
  Takada Y et al. Identification of a p65 peptide that selectively inhibits NF-kappa B activation induced by various inflammatory stimuli and its role in down-regulation of NF-kappaB-mediated gene expression and up-regulation of apoptosis. J. Biol. Chem. 20
  Takada Y et al
  2004/01/01
  
• 備考：
  
• 参照：
  

• No.： 6
• 文献情報：
  Ichikawa H et al. Identification of a novel blocker of I kappa B alpha kinase that enhances cellular apoptosis and inhibits cellular invasion through suppression of NF-kappa B-regulated gene products. J. Immunol. 2005 Jun;174(11):7383-92
  Ichikawa H et al
  2005/01/01
  
• 備考：
  
• 参照：
  

• No.： 7
• 文献情報：
  Anto RJ et al. Cigarette smoke condensate activates nuclear transcription factor-kappaB through phosphorylation and degradation of IkappaB(alpha): correlation with induction of cyclooxygenase-2. Carcinogenesis 2002 Sep;23(9):1511-8
  Anto RJ et al
  2002/01/01
  
• 備考：
  
• 参照：
  

• No.： 8
• 文献情報：
  Takada Y et al. Genetic deletion of glycogen synthase kinase-3beta abrogates activation of IkappaBalpha kinase, JNK, Akt, and p44/p42 MAPK but potentiates apoptosis induced by tumor necrosis factor. J. Biol. Chem. 2004 Sep;279(38):39541-54
  Takada Y et al
  2004/01/01
  
• 備考：
  
• 参照：
  

• No.： 9
• 文献情報：
  Jackson-Bernitsas DG et al. Evidence that TNF-TNFR1-TRADD-TRAF2-RIP-TAK1-IKK pathway mediates constitutive NF-kappaB activation and proliferation in human head and neck squamous cell carcinoma. Oncogene 2007 Mar;26(10):1385-97
  Jackson-Bernitsas DG et al
  2007/01/01
  
• 備考：
  
• 参照：
  

• No.： 10
• 文献情報：
  Saito N et al. Two carboxyl-terminal activation regions of Epstein-Barr virus latent membrane protein 1 activate NF-kappaB through distinct signaling pathways in fibroblast cell lines. J. Biol. Chem. 2003 Nov;278(47):46565-75
  Saito N et al
  2003/01/01
  
• 備考：
  
• 参照：
  

• No.： 11
• 文献情報：
  Miller BS et al. Complete reconstitution of human IkappaB kinase (IKK) complex in yeast. Assessment of its stoichiometry and the role of IKKgamma on the complex activity in the absence of stimulation. J. Biol. Chem. 2001 Sep;276(39):36320-6
  Miller BS et al
  2001/01/01
  
• 備考：
  
• 参照：
  

• No.： 12
• 文献情報：
  Ichikawa H et al. Guggulsterone inhibits osteoclastogenesis induced by receptor activator of nuclear factor-kappaB ligand and by tumor cells by suppressing nuclear factor-kappaB activation. Clin. Cancer Res. 2006 Jan;12(2):662-8
  Ichikawa H et al
  2006/01/01
  
• 備考：
  
• 参照：
  

• No.： 13
• 文献情報：
  Ashikawa K et al. Piceatannol inhibits TNF-induced NF-kappaB activation and NF-kappaB-mediated gene expression through suppression of IkappaBalpha kinase and p65 phosphorylation. J. Immunol. 2002 Dec;169(11):6490-7
  Ashikawa K et al
  2002/01/01
  
• 備考：
  
• 参照：
  

• No.： 14
• 文献情報：
  Kasinski AL et al. Inhibition of IkappaB kinase-nuclear factor-kappaB signaling pathway by 3,5-bis(2-flurobenzylidene)piperidin-4-one (EF24), a novel monoketone analog of curcumin. Mol. Pharmacol. 2008 Sep;74(3):654-61
  Kasinski AL et al
  2008/01/01
  
• 備考：
  
• 参照：
  

• No.： 15
• 文献情報：
  Manna SK et al. Leflunomide suppresses TNF-induced cellular responses: effects on NF-kappa B, activator protein-1, c-Jun N-terminal protein kinase, and apoptosis. J. Immunol. 2000 Nov;165(10):5962-9
  Manna SK et al
  2000/01/01
  
• 備考：
  
• 参照：
  

• No.： 16
• 文献情報：
  Ruocco MG et al. I{kappa}B kinase (IKK){beta}, but not IKK{alpha}, is a critical mediator of osteoclast survival and is required for inflammation-induced bone loss. J. Exp. Med. 2005 May;201(10):1677-87
  Ruocco MG et al
  2005/01/01
  
• 備考：
  
• 参照：
  

• No.： 17
• 文献情報：
  Majumdar S et al. Thalidomide suppresses NF-kappa B activation induced by TNF and H2O2, but not that activated by ceramide, lipopolysaccharides, or phorbol ester. J. Immunol. 2002 Mar;168(6):2644-51
  Majumdar S et al
  2002/01/01
  
• 備考：
  
• 参照：
  

• No.： 18
• 文献情報：
  Chandrasekar B et al. Activation of intrinsic and extrinsic proapoptotic signaling pathways in interleukin-18-mediated human cardiac endothelial cell death. J. Biol. Chem. 2004 May;279(19):20221-33
  Chandrasekar B et al
  2004/01/01
  
• 備考：
  
• 参照：
  

• No.： 19
• 文献情報：
  Chen LW et al. The two faces of IKK and NF-kappaB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion. Nat. Med. 2003 May;9(5):575-81
  Chen LW et al
  2003/01/01
  
• 備考：
  
• 参照：
  

• No.： 20
• 文献情報：
  Manna SK et al. IFN-alpha suppresses activation of nuclear transcription factors NF-kappa B and activator protein 1 and potentiates TNF-induced apoptosis. J. Immunol. 2000 Nov;165(9):4927-34
  Manna SK et al
  2000/01/01
  
• 備考：
  
• 参照：
  

• No.： 21
• 文献情報：
  Shishodia S et al. Guggulsterone inhibits NF-kappaB and IkappaBalpha kinase activation, suppresses expression of anti-apoptotic gene products, and enhances apoptosis. J. Biol. Chem. 2004 Nov;279(45):47148-58
  Shishodia S et al
  2004/01/01
  
• 備考：
  
• 参照：
  

• No.： 22
• 文献情報：
  Koul D et al. Tumor suppressor MMAC/PTEN inhibits cytokine-induced NFkappaB activation without interfering with the IkappaB degradation pathway. J. Biol. Chem. 2001 Apr;276(14):11402-8
  Koul D et al
  2001/01/01
  
• 備考：
  
• 参照：
  

• No.： 23
• 文献情報：
  Huang J et al. HTLV-1 Tax is a critical lipid raft modulator that hijacks IkappaB kinases to the microdomains for persistent activation of NF-kappaB. J. Biol. Chem. 2009 Mar;284(10):6208-17
  Huang J et al
  2009/01/01
  
• 備考：
  
• 参照：
  

• No.： 24
• 文献情報：
  Otipoby KL et al. BAFF activates Akt and Erk through BAFF-R in an IKK1-dependent manner in primary mouse B cells. Proc. Natl. Acad. Sci. U.S.A. 2008 Aug;105(34):12435-8
  Otipoby KL et al
  2008/01/01
  
• 備考：
  
• 参照：
  

• No.： 25
• 文献情報：
  Sethi G et al. Indirubin enhances tumor necrosis factor-induced apoptosis through modulation of nuclear factor-kappa B signaling pathway. J. Biol. Chem. 2006 Aug;281(33):23425-35
  Sethi G et al
  2006/01/01
  
• 備考：
  
• 参照：
  

• No.： 26
• 文献情報：
  Cui J et al. NLRP4 negatively regulates type I interferon signaling by targeting the kinase TBK1 for degradation via the ubiquitin ligase DTX4. Nat. Immunol. 2012 Apr;13(4):387-95
  Cui J et al
  2012/01/01
  
• 備考：
  
• 参照：
  

• No.： 27
• 文献情報：
  Majumdar S et al. Adenosine suppresses activation of nuclear factor-kappaB selectively induced by tumor necrosis factor in different cell types. Oncogene 2003 Feb;22(8):1206-18
  Majumdar S et al
  2003/01/01
  
• 備考：
  
• 参照：
  

• No.： 28
• 文献情報：
  Cao Y et al. IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development. Cell 2001 Dec;107(6):763-75
  Cao Y et al
  2001/01/01
  
• 備考：
  
• 参照：
  

• No.： 29
• 文献情報：
  Delhase M et al. TANK-binding kinase 1 (TBK1) controls cell survival through PAI-2/serpinB2 and transglutaminase 2. Proc. Natl. Acad. Sci. U.S.A. 2012 Jan;109(4):E177-86
  Delhase M et al
  2012/01/01
  
• 備考：
  
• 参照：
  

• No.： 30
• 文献情報：
  Dejardin E et al. The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways. Immunity 2002 Oct;17(4):525-35
  Dejardin E et al
  2002/01/01
  
• 備考：
  
• 参照：
  

• No.： 31
• 文献情報：
  Eckmann L et al. Opposing functions of IKKbeta during acute and chronic intestinal inflammation. Proc. Natl. Acad. Sci. U.S.A. 2008 Sep;105(39):15058-63
  Eckmann L et al
  2008/01/01
  
• 備考：
  
• 参照：
  

• No.： 32
• 文献情報：
  Majumdar S et al. Methotrexate suppresses NF-kappaB activation through inhibition of IkappaBalpha phosphorylation and degradation. J. Immunol. 2001 Sep;167(5):2911-20
  Majumdar S et al
  2001/01/01
  
• 備考：
  
• 参照：
  

• No.： 33
• 文献情報：
  Nonaka M et al. Aberrant NF-kappaB2/p52 expression in Hodgkin/Reed-Sternberg cells and CD30-transformed rat fibroblasts. Oncogene 2005 Jun;24(24):3976-86
  Nonaka M et al
  2005/01/01
  
• 備考：
  
• 参照：
  

• No.： 34
• 文献情報：
  Makris C et al. The carboxyl-terminal region of IkappaB kinase gamma (IKKgamma) is required for full IKK activation. Mol. Cell. Biol. 2002 Sep;22(18):6573-81
  Makris C et al
  2002/01/01
  
• 備考：
  
• 参照：
  

• No.： 35
• 文献情報：
  Beraza N et al. Hepatocyte-specific IKK gamma/NEMO expression determines the degree of liver injury. Gastroenterology 2007 Jun;132(7):2504-17
  Beraza N et al
  2007/01/01
  
• 備考：
  
• 参照：
  

• No.： 36
• 文献情報：
  Chinanonwait N et al. A recessive mutant cell line with a constitutive IkappaB kinase activity. FEBS Lett. 2002 Nov;531(3):553-60
  Chinanonwait N et al
  2002/01/01
  
• 備考：
  
• 参照：
  

• No.： 37
• 文献情報：
  Bakkar N et al. IKKα and alternative NF-κB regulate PGC-1β to promote oxidative muscle metabolism. J. Cell Biol. 2012 Feb;196(4):497-511
  Bakkar N et al
  2012/01/01
  
• 備考：
  
• 参照：
  

• No.： 38
• 文献情報：
  Agou F et al. NEMO trimerizes through its coiled-coil C-terminal domain. J. Biol. Chem. 2002 May;277(20):17464-75
  Agou F et al
  2002/01/01
  
• 備考：
  
• 参照：
  

• No.： 39
• 文献情報：
  Phromnoi K et al. A novel pentamethoxyflavone down-regulates tumor cell survival and proliferative and angiogenic gene products through inhibition of IκB kinase activation and sensitizes tumor cells to apoptosis by cytokines and chemotherapeutic age
  Phromnoi K et al
  2011/01/01
  
• 備考：
  
• 参照：
  

• No.： 40
• 文献情報：
  Kunnumakkara AB et al. Coronarin D, a labdane diterpene, inhibits both constitutive and inducible nuclear factor-kappa B pathway activation, leading to potentiation of apoptosis, inhibition of invasion, and suppression of osteoclastogenesis. Mol. Cancer T
  Kunnumakkara AB et al
  2008/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 41
• 文献情報：
  Pandey MK et al. Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated antiapoptotic gene products, and potentiates apoptosis. Cancer Res. 2008 Jul;68(13):5370-9
  Pandey MK et al
  2008/01/01
  
• 備考：
  
• 参照：
  

• No.： 42
• 文献情報：
  Harikumar KB et al. Escin, a pentacyclic triterpene, chemosensitizes human tumor cells through inhibition of nuclear factor-kappaB signaling pathway. Mol. Pharmacol. 2010 May;77(5):818-27
  Harikumar KB et al
  2010/01/01
  
• 備考：
  
• 参照：
  

• No.： 43
• 文献情報：
  Fang X et al. IKKα-mediated biogenesis of miR-196a through interaction with Drosha regulates the sensitivity of cancer cells to radiotherapy. Cell Death Differ. 2016 Sep;23(9):1471-82
  Fang X et al
  2016/01/01
  
• 備考：
  
• 参照：