Anti-Noxa, Mouse-Mono(114C307.1)

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• 商品コード：NB600-1159SS
• メーカー：NOV
• 包装：0.025mg
• 価格： ¥41,000
• 在庫：無(未発注)

マイリストに追加 マイリストに追加済

• No.： 1
• 文献情報：
  Sigurdsson HH et al. Constitutively Active ErbB2 Regulates Cisplatin-induced Cell Death in Breast Cancer Cells via Pro- and Anti-apoptotic Mechanisms. Mol. Cancer Res. 2014 Aug;
  Sigurdsson HH et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 2
• 文献情報：
  Amschler K et al. NF-kappaB inhibition through proteasome inhibition or IKKbeta blockade increases the susceptibility of melanoma cells to cytostatic treatment through distinct pathways. J. Invest. Dermatol. 2010 Apr;130(4):1073-86
  Amschler K et al
  2010/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 3
• 文献情報：
  Godbersen JC et al. The Nedd8-activating enzyme inhibitor MLN4924 thwarts microenvironment-driven NF-κB activation and induces apoptosis in chronic lymphocytic leukemia B cells. Clin. Cancer Res. 2014 Mar;20(6):1576-89
  Godbersen JC et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 4
• 文献情報：
  Stankiewicz AR et al. Regulation of heat-induced apoptosis by Mcl-1 degradation and its inhibition by Hsp70. Cell Death Differ. 2009 Apr;16(4):638-47
  Stankiewicz AR et al
  2009/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 5
• 文献情報：
  High LM et al. The Bcl-2 homology domain 3 mimetic ABT-737 targets the apoptotic machinery in acute lymphoblastic leukemia resulting in synergistic in vitro and in vivo interactions with established drugs. Mol. Pharmacol. 2010 Mar;77(3):483-94
  High LM et al
  2010/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 6
• 文献情報：
  Zall H et al. Chemotherapeutic drugs sensitize human renal cell carcinoma cells to ABT-737 by a mechanism involving the Noxa-dependent inactivation of Mcl-1 or A1. Mol. Cancer 2010;9:164
  Zall H et al
  2010/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 7
• 文献情報：
  Tonino SH et al. ROS-mediated upregulation of Noxa overcomes chemoresistance in chronic lymphocytic leukemia. Oncogene 2011 Feb;30(6):701-13
  Tonino SH et al
  2011/01/01
  
• 備考：
  Applications:
• 参照：
  

• No.： 8
• 文献情報：
  Pang X et al. The carboxyl-terminal tail of Noxa protein regulates the stability of Noxa and Mcl-1. J. Biol. Chem. 2014 Jun;289(25):17802-11
  Pang X et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 9
• 文献情報：
  Tromp JM et al. Tipping the Noxa/Mcl-1 balance overcomes ABT-737 resistance in chronic lymphocytic leukemia. Clin. Cancer Res. 2012 Jan;18(2):487-98
  Tromp JM et al
  2012/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 10
• 文献情報：
  Vilgelm AE et al. Interactions of the p53 protein family in cellular stress response in gastrointestinal tumors. Mol. Cancer Ther. 2010 Mar;9(3):693-705
  Vilgelm AE et al
  2010/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 11
• 文献情報：
  Hadji A et al. Caspase-3 triggers a TPCK-sensitive protease pathway leading to degradation of the BH3-only protein puma. Apoptosis 2010 Dec;15(12):1529-39
  Hadji A et al
  2010/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 12
• 文献情報：
  Fahham N et al. C-terminal domain of p16(INK4a) is adequate in inducing cell cycle arrest, growth inhibition and CDK4/6 interaction similar to the full length protein in HT-1080 fibrosarcoma cells. J. Cell. Biochem. 2010 Dec;111(6):1598-606
  Fahham N et al
  2010/01/01
  
• 備考：
  Species: Human, Applications:
• 参照：
  

• No.： 13
• 文献情報：
  Tahir SK et al. Identification of expression signatures predictive of sensitivity to the Bcl-2 family member inhibitor ABT-263 in small cell lung carcinoma and leukemia/lymphoma cell lines. Mol. Cancer Ther. 2010 Mar;9(3):545-57
  Tahir SK et al
  2010/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 14
• 文献情報：
  Paoluzzi L et al. Romidepsin and belinostat synergize the antineoplastic effect of bortezomib in mantle cell lymphoma. Clin. Cancer Res. 2010 Jan;16(2):554-65
  Paoluzzi L et al
  2010/01/01
  
• 備考：
  Species: Human, Applications:
• 参照：
  

• No.： 15
• 文献情報：
  Yoshida A et al. Inhibition of glutathione synthesis overcomes Bcl-2-mediated topoisomerase inhibitor resistance and induces nonapoptotic cell death via mitochondrial-independent pathway. Cancer Res. 2006 Jun;66(11):5772-80
  Yoshida A et al
  2006/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 16
• 文献情報：
  Chen CH et al. Energy restriction-mimetic agents induce apoptosis in prostate cancer cells in part through epigenetic activation of KLF6 tumor suppressor gene expression. J. Biol. Chem. 2011 Mar;286(12):9968-76
  Chen CH et al
  2011/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 17
• 文献情報：
  Jiang CC et al. Up-regulation of Mcl-1 is critical for survival of human melanoma cells upon endoplasmic reticulum stress. Cancer Res. 2008 Aug;68(16):6708-17
  Jiang CC et al
  2008/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 18
• 文献情報：
  Sosa Seda IM et al. Noxa mediates hepatic stellate cell apoptosis by proteasome inhibition. Hepatol. Res. 2010 Jul;40(7):701-10
  Sosa Seda IM et al
  2010/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 19
• 文献情報：
  Erster S et al. In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation. Mol. Cell. Biol. 2004 Aug;24(15):6728-41
  Erster S et al
  2004/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 20
• 文献情報：
  Yakovlev AG et al. BOK and NOXA are essential mediators of p53-dependent apoptosis. J. Biol. Chem. 2004 Jul;279(27):28367-74
  Yakovlev AG et al
  2004/01/01
  
• 備考：
  Species: Human, Applications: WB, IF/ICC
• 参照：
  

• No.： 21
• 文献情報：
  Bodet L et al. BH3-only protein Bik is involved in both apoptosis induction and sensitivity to oxidative stress in multiple myeloma. Br. J. Cancer 2010 Dec;103(12):1808-14
  Bodet L et al
  2010/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 22
• 文献情報：
  Hallaert DY et al. c-Abl kinase inhibitors overcome CD40-mediated drug resistance in CLL: implications for therapeutic targeting of chemoresistant niches. Blood 2008 Dec;112(13):5141-9
  Hallaert DY et al
  2008/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 23
• 文献情報：
  Streetly MJ et al. GCS-100, a novel galectin-3 antagonist, modulates MCL-1, NOXA, and cell cycle to induce myeloma cell death. Blood 2010 May;115(19):3939-48
  Streetly MJ et al
  2010/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 24
• 文献情報：
  Condorelli F et al. Inhibitors of histone deacetylase (HDAC) restore the p53 pathway in neuroblastoma cells. Br. J. Pharmacol. 2008 Feb;153(4):657-68
  Condorelli F et al
  2008/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 25
• 文献情報：
  Simbulan-Rosenthal CM et al. Id3 induces a caspase-3- and -9-dependent apoptosis and mediates UVB sensitization of HPV16 E6/7 immortalized human keratinocytes. Oncogene 2006 Jun;25(26):3649-60
  Simbulan-Rosenthal CM et al
  2006/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 26
• 文献情報：
  Chen WY et al. Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses. Cell 2005 Nov;123(3):437-48
  Chen WY et al
  2005/01/01
  
• 備考：
  Applications:
• 参照：
  

• No.： 27
• 文献情報：
  Deverman BE et al. Bcl-xL deamidation is a critical switch in the regulation of the response to DNA damage. Cell 2002 Oct;111(1):51-62
  Deverman BE et al
  2002/01/01
  
• 備考：
  Applications: WB,IHC-P
• 参照：
  

• No.： 28
• 文献情報：
  Tahir SK et al. Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737. Cancer Res. 2007 Feb;67(3):1176-83
  Tahir SK et al
  2007/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 29
• 文献情報：
  Chen M et al. Immune regulation through mitochondrion-dependent dendritic cell death induced by T regulatory cells. J. Immunol. 2011 Dec;187(11):5684-92
  Chen M et al
  2011/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 30
• 文献情報：
  Zhang LJ et al. Inhibition of apoptosis facilitates necrosis induced by cisplatin in gastric cancer cells. Anticancer Drugs 2008 Feb;19(2):159-66
  Zhang LJ et al
  2008/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 31
• 文献情報：
  Poulsen RC et al. Protection against glucocorticoid-induced damage in human tenocytes by modulation of ERK, Akt, and forkhead signaling. Endocrinology 2011 Feb;152(2):503-14
  Poulsen RC et al
  2011/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 32
• 文献情報：
  Rao F et al. Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2. Mol. Cell 2014 Apr;54(1):119-32
  Rao F et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 33
• 文献情報：
  Xie W et al. Novel link between E2F1 and Smac/DIABLO: proapoptotic Smac/DIABLO is transcriptionally upregulated by E2F1. Nucleic Acids Res. 2006;34(7):2046-55
  Xie W et al
  2006/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 34
• 文献情報：
  Ryder C et al. Acidosis promotes Bcl-2 family-mediated evasion of apoptosis: involvement of acid-sensing G protein-coupled receptor Gpr65 signaling to Mek/Erk. J. Biol. Chem. 2012 Aug;287(33):27863-75
  Ryder C et al
  2012/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 35
• 文献情報：
  Chu R et al. Cdk1/cyclin B plays a key role in mitotic arrest-induced apoptosis by phosphorylation of Mcl-1, promoting its degradation and freeing Bak from sequestration. Biochem. Pharmacol. 2012 Jan;83(2):199-206
  Chu R et al
  2012/01/01
  
• 備考：
  Applications:
• 参照：
  

• No.： 36
• 文献情報：
  Parrondo R et al. ABT-737, a small molecule Bcl-2/Bcl-xL antagonist, increases antimitotic-mediated apoptosis in human prostate cancer cells. PeerJ 2013;1:e144
  Parrondo R et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 37
• 文献情報：
  Lee W et al. Overexpression of OATP1B3 confers apoptotic resistance in colon cancer. Cancer Res. 2008 Dec;68(24):10315-23
  Lee W et al
  2008/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 38
• 文献情報：
  Wong C et al. Direct visualization of Bcl-2 family protein interactions using live cell fluorescent protein redistribution assays. Cell Death Dis 2012;3:e288
  Wong C et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 39
• 文献情報：
  Smit LA et al. Differential Noxa/Mcl-1 balance in peripheral versus lymph node chronic lymphocytic leukemia cells correlates with survival capacity. Blood 2007 Feb;109(4):1660-8
  Smit LA et al
  2007/01/01
  
• 備考：
  Applications:
• 参照：
  

• No.： 40
• 文献情報：
  Mihara M et al. p53 has a direct apoptogenic role at the mitochondria. Mol. Cell 2003 Mar;11(3):577-90
  Mihara M et al
  2003/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 41
• 文献情報：
  Lopez H et al. Perturbation of the Bcl-2 network and an induced Noxa/Bcl-xL interaction trigger mitochondrial dysfunction after DNA damage. J. Biol. Chem. 2010 May;285(20):15016-26
  Lopez H et al
  2010/01/01
  
• 備考：
  Applications:
• 参照：
  

• No.： 42
• 文献情報：
  Dabir S et al. PIAS3 activates the intrinsic apoptotic pathway in non-small cell lung cancer cells independent of p53 status. Int. J. Cancer 2014 Mar;134(5):1045-54
  Dabir S et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 43
• 文献情報：
  Wroblewski D et al. OBATOCLAX and ABT-737 Induce ER Stress Responses in Human Melanoma Cells that Limit Induction of Apoptosis. PLoS ONE 2013;8(12):e84073
  Wroblewski D et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 44
• 文献情報：
  Thorburn J et al. Autophagy controls the kinetics and extent of mitochondrial apoptosis by regulating PUMA levels. Cell Rep 2014 Apr;7(1):45-52
  Thorburn J et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 45
• 文献情報：
  Zinn RL et al. Combination treatment with ABT-737 and chloroquine in preclinical models of small cell lung cancer. Mol. Cancer 2013;12:16
  Zinn RL et al
  2013/01/01
  
• 備考：
  Applications:
• 参照：
  

• No.： 46
• 文献情報：
  Thomas RL et al. Loss of MCL-1 leads to impaired autophagy and rapid development of heart failure. Genes Dev. 2013 Jun;27(12):1365-77
  Thomas RL et al
  2013/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 47
• 文献情報：
  Kojima K et al. MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy. Blood 2005 Nov;106(9):3150-9
  Kojima K et al
  2005/01/01
  
• 備考：
  
• 参照：
  

• No.： 48
• 文献情報：
  Adamski J et al. Hypoxia-induced cytotoxic drug resistance in osteosarcoma is independent of HIF-1Alpha. PLoS ONE 2013;8(6):e65304
  Adamski J et al
  2013/01/01
  
• 備考：
  
• 参照：
  

• No.： 49
• 文献情報：
  Wei J et al. Bacterial CagA protein induces degradation of p53 protein in a p14ARF-dependent manner. Gut 2014 Jul;
  Wei J et al
  2014/01/01
  
• 備考：
  
• 参照：