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在庫・価格 : 2024年05月18日 08時02分 現在

商品名 商品コード メーカー 包装 価格 在庫 リスト
Anti-Noxa, Mouse-Mono(114C307.1)
データシート
NB600-1159 NOVノバス バイオロジカルス
Novus biologicals, LLC
0.1 mg ¥103,000
(未発注)
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在庫・価格 : 2024年05月18日 08時02分 現在

Anti-Noxa, Mouse-Mono(114C307.1)

  • 商品コード:NB600-1159
  • メーカー:NOV
  • 包装:0.1mg
  • 価格: ¥103,000
  • 在庫:無(未発注)
使用文献
No. 文献情報 備考 参照
1 Yakovlev AG et al. BOK and NOXA are essential mediators of p53-dependent apoptosis. J. Biol. Chem. 2004 Jul;279(27):28367-74
Yakovlev AG et al
2004/01/01
PubMed
2 Deverman BE et al. Bcl-xL deamidation is a critical switch in the regulation of the response to DNA damage. Cell 2002 Oct;111(1):51-62
Deverman BE et al
2002/01/01
PubMed
3 Mihara M et al. p53 has a direct apoptogenic role at the mitochondria. Mol. Cell 2003 Mar;11(3):577-90
Mihara M et al
2003/01/01
PubMed
4 Erster S et al. In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation. Mol. Cell. Biol. 2004 Aug;24(15):6728-41
Erster S et al
2004/01/01
PubMed
5 Chen WY et al. Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses. Cell 2005 Nov;123(3):437-48
Chen WY et al
2005/01/01
PubMed
6 Simbulan-Rosenthal CM et al. Id3 induces a caspase-3- and -9-dependent apoptosis and mediates UVB sensitization of HPV16 E6/7 immortalized human keratinocytes. Oncogene 2006 Jun;25(26):3649-60
Simbulan-Rosenthal CM et al
2006/01/01
PubMed
7 Xie W et al. Novel link between E2F1 and Smac/DIABLO: proapoptotic Smac/DIABLO is transcriptionally upregulated by E2F1. Nucleic Acids Res. 2006;34(7):2046-55
Xie W et al
2006/01/01
PubMed
8 Yoshida A et al. Inhibition of glutathione synthesis overcomes Bcl-2-mediated topoisomerase inhibitor resistance and induces nonapoptotic cell death via mitochondrial-independent pathway. Cancer Res. 2006 Jun;66(11):5772-80
Yoshida A et al
2006/01/01
PubMed
9 Ryder C et al. Acidosis promotes Bcl-2 family-mediated evasion of apoptosis: involvement of acid-sensing G protein-coupled receptor Gpr65 signaling to Mek/Erk. J. Biol. Chem. 2012 Aug;287(33):27863-75
Ryder C et al
2012/01/01
Species: Mouse, Applications: WB PubMed
10 1. NOXA (IMG-349A) [WB, Fig 4ACD (primary human mammary epithelial cells, HMEC) ] .

PubMed
11 1. NOXA (IMG-349) [WB, Fig 7AB, (Rb null osteosarcoma cell line, SAOS-2) ].

PubMed
12 Noxa (IMG-349) [WB, Fig.1A-C (697-Neo cells) Fig.1D (697-Bcl-2 cells)].

PubMed
13 NOXA (IMG-349A) [WB, Fig 2B (p53 transfected H1299 cells) ].

PubMed
14 p53 siRNA Ready Gene (IMG-803) [WB, Fig 2AB (MCF-7 cells) ].

PubMed
15 Noxa (IMG-349) [WB, Fig.4 (H1299 cells)].

PubMed
16 Wong C et al. Direct visualization of Bcl-2 family protein interactions using live cell fluorescent protein redistribution assays. Cell Death Dis 2012;3:e288
Wong C et al
2012/01/01
Species: Human, Applications: ICC/IF PubMed
17 1 NOXA (IMG-349A) [WB, Fig 4ACD (primary human mammary epithelial cells, HMEC) ].

PubMed
18 1 NOXA (IMG-349) [WB, Fig 7AB, (Rb null osteosarcoma cell line, SAOS-2) ].

PubMed
19 Noxa (IMG-349) [WB, Fig1A-C (697-Neo cells) Fig1D (697-Bcl-2 cells)].

PubMed
20 Noxa (IMG-349) [WB, Fig4 (H1299 cells)].

PubMed
21 Thomas RL et al. Loss of MCL-1 leads to impaired autophagy and rapid development of heart failure. Genes Dev. 2013 Jun;27(12):1365-77
Thomas RL et al
2013/01/01
Species: Mouse, Applications: WB PubMed
22 Fahham N et al. C-terminal domain of p16(INK4a) is adequate in inducing cell cycle arrest, growth inhibition and CDK4/6 interaction similar to the full length protein in HT-1080 fibrosarcoma cells. J. Cell. Biochem. 2010 Dec;111(6):1598-606
Fahham N et al
2010/01/01
PubMed
23 Tahir SK et al. Identification of expression signatures predictive of sensitivity to the Bcl-2 family member inhibitor ABT-263 in small cell lung carcinoma and leukemia/lymphoma cell lines. Mol. Cancer Ther. 2010 Mar;9(3):545-57
Tahir SK et al
2010/01/01
PubMed
24 Chu R et al. Cdk1/cyclin B plays a key role in mitotic arrest-induced apoptosis by phosphorylation of Mcl-1, promoting its degradation and freeing Bak from sequestration. Biochem. Pharmacol. 2012 Jan;83(2):199-206
Chu R et al
2012/01/01
PubMed
25 Parrondo R et al. ABT-737, a small molecule Bcl-2/Bcl-xL antagonist, increases antimitotic-mediated apoptosis in human prostate cancer cells. PeerJ 2013;1:e144
Parrondo R et al
2013/01/01
Species: Human, Applications: WB PubMed
26 Chen CH et al. Energy restriction-mimetic agents induce apoptosis in prostate cancer cells in part through epigenetic activation of KLF6 tumor suppressor gene expression. J. Biol. Chem. 2011 Mar;286(12):9968-76
Chen CH et al
2011/01/01
PubMed
27 Zall H et al. Chemotherapeutic drugs sensitize human renal cell carcinoma cells to ABT-737 by a mechanism involving the Noxa-dependent inactivation of Mcl-1 or A1. Mol. Cancer 2010;9:164
Zall H et al
2010/01/01
PubMed
28 Hallaert DY et al. c-Abl kinase inhibitors overcome CD40-mediated drug resistance in CLL: implications for therapeutic targeting of chemoresistant niches. Blood 2008 Dec;112(13):5141-9
Hallaert DY et al
2008/01/01
PubMed
29 Smit LA et al. Differential Noxa/Mcl-1 balance in peripheral versus lymph node chronic lymphocytic leukemia cells correlates with survival capacity. Blood 2007 Feb;109(4):1660-8
Smit LA et al
2007/01/01
PubMed
30 Lopez H et al. Perturbation of the Bcl-2 network and an induced Noxa/Bcl-xL interaction trigger mitochondrial dysfunction after DNA damage. J. Biol. Chem. 2010 May;285(20):15016-26
Lopez H et al
2010/01/01
PubMed
31 Dabir S et al. PIAS3 activates the intrinsic apoptotic pathway in non-small cell lung cancer cells independent of p53 status. Int. J. Cancer 2014 Mar;134(5):1045-54
Dabir S et al
2014/01/01
Species: Human, Applications: WB PubMed
32 Bodet L et al. BH3-only protein Bik is involved in both apoptosis induction and sensitivity to oxidative stress in multiple myeloma. Br. J. Cancer 2010 Dec;103(12):1808-14
Bodet L et al
2010/01/01
PubMed
33 Poulsen RC et al. Protection against glucocorticoid-induced damage in human tenocytes by modulation of ERK, Akt, and forkhead signaling. Endocrinology 2011 Feb;152(2):503-14
Poulsen RC et al
2011/01/01
PubMed
34 Jiang CC et al. Up-regulation of Mcl-1 is critical for survival of human melanoma cells upon endoplasmic reticulum stress. Cancer Res. 2008 Aug;68(16):6708-17
Jiang CC et al
2008/01/01
PubMed
35 Stankiewicz AR et al. Regulation of heat-induced apoptosis by Mcl-1 degradation and its inhibition by Hsp70. Cell Death Differ. 2009 Apr;16(4):638-47
Stankiewicz AR et al
2009/01/01
PubMed
36 Tahir SK et al. Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737. Cancer Res. 2007 Feb;67(3):1176-83
Tahir SK et al
2007/01/01
PubMed
37 Paoluzzi L et al. Romidepsin and belinostat synergize the antineoplastic effect of bortezomib in mantle cell lymphoma. Clin. Cancer Res. 2010 Jan;16(2):554-65
Paoluzzi L et al
2010/01/01
PubMed
38 Zinn RL et al. Combination treatment with ABT-737 and chloroquine in preclinical models of small cell lung cancer. Mol. Cancer 2013;12:16
Zinn RL et al
2013/01/01
PubMed
39 Hadji A et al. Caspase-3 triggers a TPCK-sensitive protease pathway leading to degradation of the BH3-only protein puma. Apoptosis 2010 Dec;15(12):1529-39
Hadji A et al
2010/01/01
PubMed
40 Streetly MJ et al. GCS-100, a novel galectin-3 antagonist, modulates MCL-1, NOXA, and cell cycle to induce myeloma cell death. Blood 2010 May;115(19):3939-48
Streetly MJ et al
2010/01/01
PubMed
41 Vilgelm AE et al. Interactions of the p53 protein family in cellular stress response in gastrointestinal tumors. Mol. Cancer Ther. 2010 Mar;9(3):693-705
Vilgelm AE et al
2010/01/01
PubMed
42 Tromp JM et al. Tipping the Noxa/Mcl-1 balance overcomes ABT-737 resistance in chronic lymphocytic leukemia. Clin. Cancer Res. 2012 Jan;18(2):487-98
Tromp JM et al
2012/01/01
PubMed
43 Tonino SH et al. ROS-mediated upregulation of Noxa overcomes chemoresistance in chronic lymphocytic leukemia. Oncogene 2011 Feb;30(6):701-13
Tonino SH et al
2011/01/01
PubMed
44 Condorelli F et al. Inhibitors of histone deacetylase (HDAC) restore the p53 pathway in neuroblastoma cells. Br. J. Pharmacol. 2008 Feb;153(4):657-68
Condorelli F et al
2008/01/01
PubMed
45 Kojima K et al. MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy. Blood 2005 Nov;106(9):3150-9
Kojima K et al
2005/01/01
PubMed
46 Chen M et al. Immune regulation through mitochondrion-dependent dendritic cell death induced by T regulatory cells. J. Immunol. 2011 Dec;187(11):5684-92
Chen M et al
2011/01/01
PubMed
47 Zhang LJ et al. Inhibition of apoptosis facilitates necrosis induced by cisplatin in gastric cancer cells. Anticancer Drugs 2008 Feb;19(2):159-66
Zhang LJ et al
2008/01/01
PubMed
48 Adamski J et al. Hypoxia-induced cytotoxic drug resistance in osteosarcoma is independent of HIF-1Alpha. PLoS ONE 2013;8(6):e65304
Adamski J et al
2013/01/01
PubMed
49 Sosa Seda IM et al. Noxa mediates hepatic stellate cell apoptosis by proteasome inhibition. Hepatol. Res. 2010 Jul;40(7):701-10
Sosa Seda IM et al
2010/01/01
PubMed
50 Lee W et al. Overexpression of OATP1B3 confers apoptotic resistance in colon cancer. Cancer Res. 2008 Dec;68(24):10315-23
Lee W et al
2008/01/01
PubMed
51 High LM et al. The Bcl-2 homology domain 3 mimetic ABT-737 targets the apoptotic machinery in acute lymphoblastic leukemia resulting in synergistic in vitro and in vivo interactions with established drugs. Mol. Pharmacol. 2010 Mar;77(3):483-94
High LM et al
2010/01/01
PubMed
52 Amschler K et al. NF-kappaB inhibition through proteasome inhibition or IKKbeta blockade increases the susceptibility of melanoma cells to cytostatic treatment through distinct pathways. J. Invest. Dermatol. 2010 Apr;130(4):1073-86
Amschler K et al
2010/01/01
PubMed
53 Wroblewski D et al. OBATOCLAX and ABT-737 Induce ER Stress Responses in Human Melanoma Cells that Limit Induction of Apoptosis. PLoS ONE 2013;8(12):e84073
Wroblewski D et al
2013/01/01
PubMed
54 Sigurdsson HH et al. Constitutively Active ErbB2 Regulates Cisplatin-induced Cell Death in Breast Cancer Cells via Pro- and Anti-apoptotic Mechanisms. Mol. Cancer Res. 2014 Aug;
Sigurdsson HH et al
2014/01/01
Species: Human, Applications: WB PubMed
55 Godbersen JC et al. The Nedd8-activating enzyme inhibitor MLN4924 thwarts microenvironment-driven NF-κB activation and induces apoptosis in chronic lymphocytic leukemia B cells. Clin. Cancer Res. 2014 Mar;20(6):1576-89
Godbersen JC et al
2014/01/01
Species: Human, Applications: WB PubMed
56 Pang X et al. The carboxyl-terminal tail of Noxa protein regulates the stability of Noxa and Mcl-1. J. Biol. Chem. 2014 Jun;289(25):17802-11
Pang X et al
2014/01/01
Species: Human, Applications: WB PubMed
57 Rao F et al. Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2. Mol. Cell 2014 Apr;54(1):119-32
Rao F et al
2014/01/01
Species: Human, Applications: WB PubMed
58 Thorburn J et al. Autophagy controls the kinetics and extent of mitochondrial apoptosis by regulating PUMA levels. Cell Rep 2014 Apr;7(1):45-52
Thorburn J et al
2014/01/01
Species: Human, Applications: WB PubMed
59 Wei J et al. Bacterial CagA protein induces degradation of p53 protein in a p14ARF-dependent manner. Gut 2014 Jul;
Wei J et al
2014/01/01
PubMed
60 Heinemann A et al. Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling. Oncotarget 2015 Aug;6(25):21507-21
Heinemann A et al
2015/01/01
Species: Human, Applications: WB PubMed
61 Wang Y et al. Apoptosis induced by Ginkgo biloba (EGb761) in melanoma cells is Mcl-1-dependent. PLoS ONE 2015;10(4):e0124812
Wang Y et al
2015/01/01
Species: Human, Applications: WB PubMed
62 Kuo KK et al. Involvement of phorbol-12-myristate-13-acetate-induced protein 1 in goniothalamin-induced TP53-dependent and -independent apoptosis in hepatocellular carcinoma-derived cells. Toxicol. Appl. Pharmacol. 2011 Oct;256(1):8-23
Kuo KK et al
2011/01/01
Species: Human, Applications: WB PubMed
63 Burgos JM et al. Expression of BfrH, a putative siderophore receptor of Bordetella bronchiseptica, is regulated by iron, Fur1, and the extracellular function sigma factor EcfI. Infect. Immun. 2010 Mar;78(3):1147-62
Burgos JM et al
2010/01/01
PubMed
64 Cheung M et al. The promyelocytic leukemia zinc-finger gene, PLZF, is frequently downregulated in malignant mesothelioma cells and contributes to cell survival. Oncogene 2010 Mar;29(11):1633-40
Cheung M et al
2010/01/01
Species: Human, Applications: WB PubMed
65 Ackler S et al. The Bcl-2 inhibitor ABT-263 enhances the response of multiple chemotherapeutic regimens in hematologic tumors in vivo. Cancer Chemother. Pharmacol. 2010 Oct;66(5):869-80
Ackler S et al
2010/01/01
PubMed
66 Yu F et al. Involvement of BH3-only proapoptotic proteins in mitochondrial-dependent Phenoxodiol-induced apoptosis of human melanoma cells. Anticancer Drugs 2006 Nov;17(10):1151-61
Yu F et al
2006/01/01
Species: Human PubMed
67 Pascutti MF et al. IL-21 and CD40L signals from autologous T cells can induce antigen-independent proliferation of CLL cells. Blood 2013 Oct;122(17):3010-9
Pascutti MF et al
2013/01/01
Species: Human PubMed
68 de Bruijn MT et al. Oncogenic KRAS sensitises colorectal tumour cells to chemotherapy by p53-dependent induction of Noxa. Br. J. Cancer 2010 Apr;102(8):1254-64
de Bruijn MT et al
2010/01/01
Applications: IHC PubMed
69 Zhang L et al. Selective involvement of BH3-only proteins and differential targets of Noxa in diverse apoptotic pathways. Cell Death Differ. 2011 May;18(5):864-73
Zhang L et al
2011/01/01
Species: Human PubMed
70 van Gent R et al. In vivo dynamics of stable chronic lymphocytic leukemia inversely correlate with somatic hypermutation levels and suggest no major leukemic turnover in bone marrow. Cancer Res. 2008 Dec;68(24):10137-44
van Gent R et al
2008/01/01
PubMed
71 Zhang J et al. Bax/Bak activation in the absence of Bid, Bim, Puma, and p53. Cell Death Dis 2016;7:e2266
Zhang J et al
2016/01/01
PubMed
72 Ishikita H. Proton-binding sites of acid-sensing ion channel 1. PLoS ONE 2011;6(2):e16920
Ishikita H
2011/01/01
PubMed
73 Minieri V et al. Targeting STAT5 or STAT5-Regulated Pathways Suppresses Leukemogenesis of Ph+ Acute Lymphoblastic Leukemia. Cancer Res. 2018 Oct;78(20):5793-5807
Minieri V et al
2018/01/01
Species: Human, Applications: WB PubMed
74 Antignani A et al. Essential role for Bim in mediating the apoptotic and antitumor activities of immunotoxins. Oncogene 2017 08;36(35):4953-4962
Antignani A et al
2017/01/01
Species: Mouse, Applications: WB PubMed
75 Pilling AB et al. Targeting prosurvival BCL2 signaling through Akt blockade sensitizes castration-resistant prostate cancer cells to enzalutamide. Prostate 2019 08;79(11):1347-1359
Pilling AB et al
2019/01/01
PubMed
76 Tseng HY et al. Co-targeting bromodomain and extra-terminal proteins and MCL1 induces synergistic cell death in melanoma. Int J Cancer 2020 10;147(8):2176-2189
Tseng HY et al
2020/01/01
PubMed
77 Djajawi TM et al. MARCH5 requires MTCH2 to coordinate proteasomal turnover of the MCL1:NOXA complex. Cell Death Differ 2020 08;27(8):2484-2499
Djajawi TM et al
2020/01/01
PubMed
78 Zheng J et al. Cadmium induces apoptosis via generating reactive oxygen species to activate mitochondrial p53 pathway in primary rat osteoblasts. Toxicology 2020 12;446:152611
Zheng J et al
2020/01/01
PubMed
  • No.: 1
  • 文献情報:
    Yakovlev AG et al. BOK and NOXA are essential mediators of p53-dependent apoptosis. J. Biol. Chem. 2004 Jul;279(27):28367-74
    Yakovlev AG et al
    2004/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 2
  • 文献情報:
    Deverman BE et al. Bcl-xL deamidation is a critical switch in the regulation of the response to DNA damage. Cell 2002 Oct;111(1):51-62
    Deverman BE et al
    2002/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 3
  • 文献情報:
    Mihara M et al. p53 has a direct apoptogenic role at the mitochondria. Mol. Cell 2003 Mar;11(3):577-90
    Mihara M et al
    2003/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 4
  • 文献情報:
    Erster S et al. In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation. Mol. Cell. Biol. 2004 Aug;24(15):6728-41
    Erster S et al
    2004/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 5
  • 文献情報:
    Chen WY et al. Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses. Cell 2005 Nov;123(3):437-48
    Chen WY et al
    2005/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 6
  • 文献情報:
    Simbulan-Rosenthal CM et al. Id3 induces a caspase-3- and -9-dependent apoptosis and mediates UVB sensitization of HPV16 E6/7 immortalized human keratinocytes. Oncogene 2006 Jun;25(26):3649-60
    Simbulan-Rosenthal CM et al
    2006/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 7
  • 文献情報:
    Xie W et al. Novel link between E2F1 and Smac/DIABLO: proapoptotic Smac/DIABLO is transcriptionally upregulated by E2F1. Nucleic Acids Res. 2006;34(7):2046-55
    Xie W et al
    2006/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 8
  • 文献情報:
    Yoshida A et al. Inhibition of glutathione synthesis overcomes Bcl-2-mediated topoisomerase inhibitor resistance and induces nonapoptotic cell death via mitochondrial-independent pathway. Cancer Res. 2006 Jun;66(11):5772-80
    Yoshida A et al
    2006/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 9
  • 文献情報:
    Ryder C et al. Acidosis promotes Bcl-2 family-mediated evasion of apoptosis: involvement of acid-sensing G protein-coupled receptor Gpr65 signaling to Mek/Erk. J. Biol. Chem. 2012 Aug;287(33):27863-75
    Ryder C et al
    2012/01/01
  • 備考:
    Species: Mouse, Applications: WB
  • 参照:
    PubMed
  • No.: 10
  • 文献情報:
    1. NOXA (IMG-349A) [WB, Fig 4ACD (primary human mammary epithelial cells, HMEC) ] .

  • 備考:
  • 参照:
    PubMed
  • No.: 11
  • 文献情報:
    1. NOXA (IMG-349) [WB, Fig 7AB, (Rb null osteosarcoma cell line, SAOS-2) ].

  • 備考:
  • 参照:
    PubMed
  • No.: 12
  • 文献情報:
    Noxa (IMG-349) [WB, Fig.1A-C (697-Neo cells) Fig.1D (697-Bcl-2 cells)].

  • 備考:
  • 参照:
    PubMed
  • No.: 13
  • 文献情報:
    NOXA (IMG-349A) [WB, Fig 2B (p53 transfected H1299 cells) ].

  • 備考:
  • 参照:
    PubMed
  • No.: 14
  • 文献情報:
    p53 siRNA Ready Gene (IMG-803) [WB, Fig 2AB (MCF-7 cells) ].

  • 備考:
  • 参照:
    PubMed
  • No.: 15
  • 文献情報:
    Noxa (IMG-349) [WB, Fig.4 (H1299 cells)].

  • 備考:
  • 参照:
    PubMed
  • No.: 16
  • 文献情報:
    Wong C et al. Direct visualization of Bcl-2 family protein interactions using live cell fluorescent protein redistribution assays. Cell Death Dis 2012;3:e288
    Wong C et al
    2012/01/01
  • 備考:
    Species: Human, Applications: ICC/IF
  • 参照:
    PubMed
  • No.: 17
  • 文献情報:
    1 NOXA (IMG-349A) [WB, Fig 4ACD (primary human mammary epithelial cells, HMEC) ].

  • 備考:
  • 参照:
    PubMed
  • No.: 18
  • 文献情報:
    1 NOXA (IMG-349) [WB, Fig 7AB, (Rb null osteosarcoma cell line, SAOS-2) ].

  • 備考:
  • 参照:
    PubMed
  • No.: 19
  • 文献情報:
    Noxa (IMG-349) [WB, Fig1A-C (697-Neo cells) Fig1D (697-Bcl-2 cells)].

  • 備考:
  • 参照:
    PubMed
  • No.: 20
  • 文献情報:
    Noxa (IMG-349) [WB, Fig4 (H1299 cells)].

  • 備考:
  • 参照:
    PubMed
  • No.: 21
  • 文献情報:
    Thomas RL et al. Loss of MCL-1 leads to impaired autophagy and rapid development of heart failure. Genes Dev. 2013 Jun;27(12):1365-77
    Thomas RL et al
    2013/01/01
  • 備考:
    Species: Mouse, Applications: WB
  • 参照:
    PubMed
  • No.: 22
  • 文献情報:
    Fahham N et al. C-terminal domain of p16(INK4a) is adequate in inducing cell cycle arrest, growth inhibition and CDK4/6 interaction similar to the full length protein in HT-1080 fibrosarcoma cells. J. Cell. Biochem. 2010 Dec;111(6):1598-606
    Fahham N et al
    2010/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 23
  • 文献情報:
    Tahir SK et al. Identification of expression signatures predictive of sensitivity to the Bcl-2 family member inhibitor ABT-263 in small cell lung carcinoma and leukemia/lymphoma cell lines. Mol. Cancer Ther. 2010 Mar;9(3):545-57
    Tahir SK et al
    2010/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 24
  • 文献情報:
    Chu R et al. Cdk1/cyclin B plays a key role in mitotic arrest-induced apoptosis by phosphorylation of Mcl-1, promoting its degradation and freeing Bak from sequestration. Biochem. Pharmacol. 2012 Jan;83(2):199-206
    Chu R et al
    2012/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 25
  • 文献情報:
    Parrondo R et al. ABT-737, a small molecule Bcl-2/Bcl-xL antagonist, increases antimitotic-mediated apoptosis in human prostate cancer cells. PeerJ 2013;1:e144
    Parrondo R et al
    2013/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 26
  • 文献情報:
    Chen CH et al. Energy restriction-mimetic agents induce apoptosis in prostate cancer cells in part through epigenetic activation of KLF6 tumor suppressor gene expression. J. Biol. Chem. 2011 Mar;286(12):9968-76
    Chen CH et al
    2011/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 27
  • 文献情報:
    Zall H et al. Chemotherapeutic drugs sensitize human renal cell carcinoma cells to ABT-737 by a mechanism involving the Noxa-dependent inactivation of Mcl-1 or A1. Mol. Cancer 2010;9:164
    Zall H et al
    2010/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 28
  • 文献情報:
    Hallaert DY et al. c-Abl kinase inhibitors overcome CD40-mediated drug resistance in CLL: implications for therapeutic targeting of chemoresistant niches. Blood 2008 Dec;112(13):5141-9
    Hallaert DY et al
    2008/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 29
  • 文献情報:
    Smit LA et al. Differential Noxa/Mcl-1 balance in peripheral versus lymph node chronic lymphocytic leukemia cells correlates with survival capacity. Blood 2007 Feb;109(4):1660-8
    Smit LA et al
    2007/01/01
  • 備考:
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