Anti-ChREBP, Rabbit-Poly

データシート

• 商品コード：NB400-135
• メーカー：NOV
• 包装：0.1ml
• 価格： ¥103,000
• 在庫：無(未発注)

マイリストに追加 マイリストに追加済

• No.： 1
• 文献情報：
  Xu J et al. Regulation of rat hepatic L-pyruvate kinase promoter composition and activity by glucose, n-3 polyunsaturated fatty acids, and peroxisome proliferator-activated receptor-alpha agonist. J. Biol. Chem. 2006 Jul;281(27):18351-62
  Xu J et al
  2006/01/01
  
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• No.： 2
• 文献情報：
  Wang Y et al. Regulation of hepatic fatty acid elongase and desaturase expression in diabetes and obesity. J. Lipid Res. 2006 Sep;47(9):2028-41
  Wang Y et al
  2006/01/01
  
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• 参照：
  

• No.： 3
• 文献情報：
  Dentin R et al. Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice. Diabetes 2006 Aug;55(8):2159-70
  Dentin R et al
  2006/01/01
  
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• 参照：
  

• No.： 4
• 文献情報：
  Marmugi A et al. Low doses of bisphenol A induce gene expression related to lipid synthesis and trigger triglyceride accumulation in adult mouse liver. Hepatology 2012 Feb;55(2):395-407
  Marmugi A et al
  2012/01/01
  
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• 参照：
  

• No.： 5
• 文献情報：
  Vidal-Alabr坦 A et al. Liver Glucokinase(A456V) Induces Potent Hypoglycemia without Dyslipidemia through a Paradoxical Induction of the Catalytic Subunit of Glucose-6-Phosphatase. Int J Endocrinol 2011;2011:707928
  Vidal-Alabr坦 A et al
  2011/01/01
  
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• 参照：
  

• No.： 6
• 文献情報：
  Iizuka K et al. Rat glucagon receptor mRNA is directly regulated by glucose through transactivation of the carbohydrate response element binding protein. Biochem. Biophys. Res. Commun. 2012 Jan;417(4):1107-12
  Iizuka K et al
  2012/01/01
  
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• 参照：
  

• No.： 7
• 文献情報：
  Larter CZ et al. Peroxisome proliferator-activated receptor-α agonist, Wy 14,643, improves metabolic indices, steatosis and ballooning in diabetic mice with non-alcoholic steatohepatitis. J. Gastroenterol. Hepatol. 2012 Feb;27(2):341-50
  Larter CZ et al
  2012/01/01
  
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• 参照：
  

• No.： 8
• 文献情報：
  Sirek AS et al. Insulin stimulates the expression of carbohydrate response element binding protein (ChREBP) by attenuating the repressive effect of Pit-1, Oct-1/Oct-2, and Unc-86 homeodomain protein octamer transcription factor-1. Endocrinology 2009 Aug;1
  Sirek AS et al
  2009/01/01
  
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• 参照：
  

• No.： 9
• 文献情報：
  Wang Y et al. Elevated hepatic fatty acid elongase-5 activity affects multiple pathways controlling hepatic lipid and carbohydrate composition. J. Lipid Res. 2008 Jul;49(7):1538-52
  Wang Y et al
  2008/01/01
  
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• 参照：
  

• No.： 10
• 文献情報：
  Shao W et al. Curcumin prevents high fat diet induced insulin resistance and obesity via attenuating lipogenesis in liver and inflammatory pathway in adipocytes. PLoS ONE 2012;7(1):e28784
  Shao W et al
  2012/01/01
  
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• 参照：
  

• No.： 11
• 文献情報：
  Kim HJ et al. Renal mass reduction results in accumulation of lipids and dysregulation of lipid regulatory proteins in the remnant kidney. Am. J. Physiol. Renal Physiol. 2009 Jun;296(6):F1297-306
  Kim HJ et al
  2009/01/01
  
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• 参照：
  

• No.： 12
• 文献情報：
  Bu SY et al. Suppression of long chain acyl-CoA synthetase 3 decreases hepatic de novo fatty acid synthesis through decreased transcriptional activity. J. Biol. Chem. 2009 Oct;284(44):30474-83
  Bu SY et al
  2009/01/01
  
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• 参照：
  

• No.： 13
• 文献情報：
  Burke SJ et al. cAMP opposes the glucose-mediated induction of the L-PK gene by preventing the recruitment of a complex containing ChREBP, HNF4alpha, and CBP. FASEB J. 2009 Sep;23(9):2855-65
  Burke SJ et al
  2009/01/01
  
• 備考：
  
• 参照：
  

• No.： 14
• 文献情報：
  Tong X et al. The glucose-responsive transcription factor ChREBP contributes to glucose-dependent anabolic synthesis and cell proliferation. Proc. Natl. Acad. Sci. U.S.A. 2009 Dec;106(51):21660-5
  Tong X et al
  2009/01/01
  
• 備考：
  
• 参照：
  

• No.： 15
• 文献情報：
  Iizuka K et al. Krüppel-like factor-10 is directly regulated by carbohydrate response element-binding protein in rat primary hepatocytes. Biochem. Biophys. Res. Commun. 2011 Sep;412(4):638-43
  Iizuka K et al
  2011/01/01
  
• 備考：
  
• 参照：
  

• No.： 16
• 文献情報：
  Jeong YS et al. Integrated expression profiling and genome-wide analysis of ChREBP targets reveals the dual role for ChREBP in glucose-regulated gene expression. PLoS ONE 2011;6(7):e22544
  Jeong YS et al
  2011/01/01
  
• 備考：
  
• 参照：
  

• No.： 17
• 文献情報：
  Erhuma A et al. Prenatal exposure to a low-protein diet programs disordered regulation of lipid metabolism in the aging rat. Am. J. Physiol. Endocrinol. Metab. 2007 Jun;292(6):E1702-14
  Erhuma A et al
  2007/01/01
  
• 備考：
  
• 参照：
  

• No.： 18
• 文献情報：
  Aneja KK et al. The presence of distal and proximal promoters for rat mitochondrial glycerol-3-phosphate acyltransferase. Arch. Biochem. Biophys. 2008 Feb;470(1):35-43
  Aneja KK et al
  2008/01/01
  
• 備考：
  
• 参照：
  

• No.： 19
• 文献情報：
  Arden C et al. Elevated glucose represses liver glucokinase and induces its regulatory protein to safeguard hepatic phosphate homeostasis. Diabetes 2011 Dec;60(12):3110-20
  Arden C et al
  2011/01/01
  
• 備考：
  
• 参照：
  

• No.： 20
• 文献情報：
  Uebanso T et al. Paradoxical regulation of human FGF21 by both fasting and feeding signals: is FGF21 a nutritional adaptation factor? PLoS ONE 2011;6(8):e22976
  Uebanso T et al
  2011/01/01
  
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• 参照：
  

• No.： 21
• 文献情報：
  Kang YJ et al. Trichinella spiralis infection induces angiogenic factor thymosin β4 expression. Vet. Parasitol. 2011 Sep;181(2-4):222-8
  Kang YJ et al
  2011/01/01
  
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• 参照：
  

• No.： 22
• 文献情報：
  Zhang P et al. c-Myc is required for the CHREBP-dependent activation of glucose-responsive genes. Mol. Endocrinol. 2010 Jun;24(6):1274-86
  Zhang P et al
  2010/01/01
  
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• 参照：
  

• No.： 23
• 文献情報：
  Boergesen M et al. ChREBP mediates glucose repression of peroxisome proliferator-activated receptor alpha expression in pancreatic beta-cells. J. Biol. Chem. 2011 Apr;286(15):13214-25
  Boergesen M et al
  2011/01/01
  
• 備考：
  
• 参照：
  

• No.： 24
• 文献情報：
  Inoue J et al. Identification of MIG12 as a mediator for stimulation of lipogenesis by LXR activation. Mol. Endocrinol. 2011 Jun;25(6):995-1005
  Inoue J et al
  2011/01/01
  
• 備考：
  
• 参照：
  

• No.： 25
• 文献情報：
  Moon YA et al. Deletion of ELOVL5 leads to fatty liver through activation of SREBP-1c in mice. J. Lipid Res. 2009 Mar;50(3):412-23
  Moon YA et al
  2009/01/01
  
• 備考：
  
• 参照：
  

• No.： 26
• 文献情報：
  Dentin R et al. Glucose 6-phosphate, rather than xylulose 5-phosphate, is required for the activation of ChREBP in response to glucose in the liver. J. Hepatol. 2012 Jan;56(1):199-209
  Dentin R et al
  2012/01/01
  
• 備考：
  Applications: WB, Species: Mouse
• 参照：
  

• No.： 27
• 文献情報：
  Perttil辰 J et al. PNPLA3 is regulated by glucose in human hepatocytes, and its I148M mutant slows down triglyceride hydrolysis. Am. J. Physiol. Endocrinol. Metab. 2012 May;302(9):E1063-9
  Perttil辰 J et al
  2012/01/01
  
• 備考：
  Applications: ChIP, Species: Human
• 参照：
  

• No.： 28
• 文献情報：
  Hagiwara A et al. Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c. Cell Metab. 2012 May;15(5):725-38
  Hagiwara A et al
  2012/01/01
  
• 備考：
  Applications: WB, Species: Mouse
• 参照：
  

• No.： 29
• 文献情報：
  Benhamed F et al. The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans. J. Clin. Invest. 2012 Jun;122(6):2176-94
  Benhamed F et al
  2012/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 30
• 文献情報：
  Oosterveer MH et al. LRH-1-dependent glucose sensing determines intermediary metabolism in liver. J. Clin. Invest. 2012 Aug;122(8):2817-26
  Oosterveer MH et al
  2012/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 31
• 文献情報：
  Feingold KR et al. Endotoxin, zymosan, and cytokines decrease the expression of the transcription factor, carbohydrate response element binding protein, and its target genes. Innate Immun 2011 Apr;17(2):174-82
  Feingold KR et al
  2011/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 32
• 文献情報：
  Arden C et al. Fructose 2,6-bisphosphate is essential for glucose-regulated gene transcription of glucose-6-phosphatase and other ChREBP target genes in hepatocytes. Biochem. J. 2012 Apr;443(1):111-23
  Arden C et al
  2012/01/01
  
• 備考：
  Applications: ChIP, ICC/IF
• 参照：
  

• No.： 33
• 文献情報：
  Guinez C et al. O-GlcNAcylation increases ChREBP protein content and transcriptional activity in the liver. Diabetes 2011 May;60(5):1399-413
  Guinez C et al
  2011/01/01
  
• 備考：
  Applications: ChIP, WB
• 参照：
  

• No.： 34
• 文献情報：
  Zhang YK et al. Nrf2 deficiency improves glucose tolerance in mice fed a high-fat diet. Toxicol. Appl. Pharmacol. 2012 Nov;264(3):305-14
  Zhang YK et al
  2012/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 35
• 文献情報：
  Ido-Kitamura Y et al. Hepatic FoxO1 Integrates Glucose Utilization and Lipid Synthesis through Regulation of Chrebp O-Glycosylation. PLoS ONE 2012;7(10):e47231
  Ido-Kitamura Y et al
  2012/01/01
  
• 備考：
  Species: Mouse, Applications: IP, WB
• 参照：
  

• No.： 36
• 文献情報：
  Jin K et al. Dysregulation of hepatic fatty acid metabolism in chronic kidney disease. Nephrol. Dial. Transplant. 2012 Oct;
  Jin K et al
  2012/01/01
  
• 備考：
  Species: Rat, Applications: WB
• 参照：
  

• No.： 37
• 文献情報：
  Petrie JL et al. Glucose induces protein targeting to glycogen in hepatocytes by fructose 2,6-bisphosphate-mediated recruitment of MondoA to the promoter. Mol. Cell. Biol. 2013 Feb;33(4):725-38
  Petrie JL et al
  2013/01/01
  
• 備考：
  Species: Rat, Applications: ChIP
• 参照：
  

• No.： 38
• 文献情報：
  Caron S et al. Farnesoid x receptor inhibits the transcriptional activity of carbohydrate response element binding protein in human hepatocytes. Mol. Cell. Biol. 2013 Jun;33(11):2202-11
  Caron S et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: ChIP
• 参照：
  

• No.： 39
• 文献情報：
  Liu Y et al. Nuclear transport modulation reduces hypercholesterolemia, atherosclerosis, and fatty liver. J Am Heart Assoc 2013 Apr;2(2):e000093
  Liu Y et al
  2013/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 40
• 文献情報：
  Han S et al. Hepatic fatty acid and cholesterol metabolism in nephrotic syndrome. Am J Transl Res 2013;5(2):246-53
  Han S et al
  2013/01/01
  
• 備考：
  Species: Rat, Applications: WB
• 参照：
  

• No.： 41
• 文献情報：
  Liu C et al. Oleanolic Acid diminishes liquid fructose-induced Fatty liver in rats: role of modulation of hepatic sterol regulatory element-binding protein-1c-mediated expression of genes responsible for de novo Fatty Acid synthesis. Evid Based Complement
  Liu C et al
  2013/01/01
  
• 備考：
  Species: Rat, Applications: WB
• 参照：
  

• No.： 42
• 文献情報：
  Burke SJ et al. cAMP prevents glucose-mediated modifications of histone H3 and recruitment of the RNA polymerase II holoenzyme to the L-PK gene promoter. J. Mol. Biol. 2009 Sep;392(3):578-88
  Burke SJ et al
  2009/01/01
  
• 備考：
  Species: Rat, Applications: ChIP
• 参照：
  

• No.： 43
• 文献情報：
  Fukasawa M et al. Coordinate regulation/localization of the carbohydrate responsive binding protein (ChREBP) by two nuclear export signal sites: discovery of a new leucine-rich nuclear export signal site. Biochem. Biophys. Res. Commun. 2010 Jan;391(2):116
  Fukasawa M et al
  2010/01/01
  
• 備考：
  Species: Rat, Applications: EMSA
• 参照：
  

• No.： 44
• 文献情報：
  Jo SH et al. Txnip contributes to impaired glucose tolerance by upregulating the expression of genes involved in hepatic gluconeogenesis in mice. Diabetologia 2013 Dec;56(12):2723-32
  Jo SH et al
  2013/01/01
  
• 備考：
  Species: Mouse, Applications: ChIP
• 参照：
  

• No.： 45
• 文献情報：
  Chambers KT et al. PGC-1β and ChREBP partner to cooperatively regulate hepatic lipogenesis in a glucose concentration-dependent manner. Mol Metab 2013;2(3):194-204
  Chambers KT et al
  2013/01/01
  
• 備考：
  Species: Mouse, Applications: WB, ChIP
• 参照：
  

• No.： 46
• 文献情報：
  Wu L et al. Flightless I homolog negatively regulates ChREBP activity in cancer cells. Int. J. Biochem. Cell Biol. 2013 Nov;45(11):2688-97
  Wu L et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: IP, WB
• 参照：
  

• No.： 47
• 文献情報：
  Liu L et al. Modulation of hepatic sterol regulatory element-binding protein-1c-mediated gene expression contributes to Salacia oblonga root-elicited improvement of fructose-induced fatty liver in rats. J Ethnopharmacol 2013 Dec;150(3):1045-52
  Liu L et al
  2013/01/01
  
• 備考：
  
• 参照：
  

• No.： 48
• 文献情報：
  Xing X et al. Mangiferin treatment inhibits hepatic expression of acyl-coenzyme A:diacylglycerol acyltransferase-2 in fructose-fed spontaneously hypertensive rats: a link to amelioration of fatty liver. Toxicol. Appl. Pharmacol. 2014 Oct;280(2):207-15
  Xing X et al
  2014/01/01
  
• 備考：
  Species: Rat, Applications: WB
• 参照：
  

• No.： 49
• 文献情報：
  Chang ML et al. High glucose activates ChREBP-mediated HIF-1α and VEGF expression in human RPE cells under normoxia. Adv. Exp. Med. Biol. 2014;801:609-21
  Chang ML et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: ChIP, WB, ICC/IF
• 参照：
  

• No.： 50
• 文献情報：
  Kaadige MR et al. MondoA-Mlx Transcriptional Activity Is Limited by mTOR-MondoA Interaction. Mol. Cell. Biol. 2015 Jan;35(1):101-10
  Kaadige MR et al
  2015/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 51
• 文献情報：
  Gupta M et al. Maternal magnesium deficiency in mice leads to maternal metabolic dysfunction and altered lipid metabolism with fetal growth restriction. Mol. Med. 2014;20:332-40
  Gupta M et al
  2014/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 52
• 文献情報：
  Cort辿s VA et al. Leptin ameliorates insulin resistance and hepatic steatosis in Agpat2-/- lipodystrophic mice independent of hepatocyte leptin receptors. J. Lipid Res. 2014 Feb;55(2):276-88
  Cort辿s VA et al
  2014/01/01
  
• 備考：
  Species: Mouse,
• 参照：
  

• No.： 53
• 文献情報：
  Bindesb淡ll C et al. Liver X receptor regulates hepatic nuclear O-GlcNAc signaling and carbohydrate responsive element-binding protein activity. J. Lipid Res. 2015 Apr;56(4):771-85
  Bindesb淡ll C et al
  2015/01/01
  
• 備考：
  Species: Mouse,
• 参照：
  

• No.： 54
• 文献情報：
  Marmier S et al. Novel role for carbohydrate responsive element binding protein in the control of ethanol metabolism and susceptibility to binge drinking. Hepatology 2015 Mar;
  Marmier S et al
  2015/01/01
  
• 備考：
  Species: Human, Applications: WB, IP
• 参照：
  

• No.： 55
• 文献情報：
  Poungvarin N et al. Genome-Wide Analysis of ChREBP Binding Sites on Male Mouse Liver and White Adipose Chromatin. Endocrinology 2015 Jun;156(6):1982-94
  Poungvarin N et al
  2015/01/01
  
• 備考：
  Species: Mouse, Applications: ChIP
• 参照：
  

• No.： 56
• 文献情報：
  Li X et al. New Insight Into Metformin Action: Regulation of ChREBP and FOXO1 Activities in Endothelial Cells. Mol. Endocrinol. 2015 Aug;29(8):1184-94
  Li X et al
  2015/01/01
  
• 備考：
  Species: Human, Mouse, Applications: ICC/IF
• 参照：
  

• No.： 57
• 文献情報：
  Cha-Molstad H et al. Glucose-stimulated expression of Txnip is mediated by carbohydrate response element-binding protein, p300, and histone H4 acetylation in pancreatic beta cells. J. Biol. Chem. 2009 Jun;284(25):16898-905
  Cha-Molstad H et al
  2009/01/01
  
• 備考：
  
• 参照：
  

• No.： 58
• 文献情報：
  Butcher AJ et al. N-methyl-D-aspartate receptors mediate the phosphorylation and desensitization of muscarinic receptors in cerebellar granule neurons. J. Biol. Chem. 2009 Jun;284(25):17147-56
  Butcher AJ et al
  2009/01/01
  
• 備考：
  Species: Mouse
• 参照：
  

• No.： 59
• 文献情報：
  Nuotio-Antar AM et al. FABP4-Cre Mediated Expression of Constitutively Active ChREBP Protects Against Obesity, Fatty Liver, and Insulin Resistance. Endocrinology 2015 Nov;156(11):4020-32
  Nuotio-Antar AM et al
  2015/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 60
• 文献情報：
  Ferreira DM et al. Comparison of the pulmonary response against lethal and non-lethal intranasal challenges with two different pneumococcal strains. Microb. Pathog. 2009 Sep;47(3):157-63
  Ferreira DM et al
  2009/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 61
• 文献情報：
  Adamson AW et al. Hepatocyte nuclear factor-4alpha contributes to carbohydrate-induced transcriptional activation of hepatic fatty acid synthase. Biochem. J. 2006 Oct;399(2):285-95
  Adamson AW et al
  2006/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 62
• 文献情報：
  Pedersen KB et al. Glucose induces expression of rat pyruvate carboxylase through a carbohydrate response element in the distal gene promoter. Biochem. J. 2010 Mar;426(2):159-70
  Pedersen KB et al
  2010/01/01
  
• 備考：
  Species: Rat
• 参照：
  

• No.： 63
• 文献情報：
  Yu FX et al. Thioredoxin-interacting protein (Txnip) gene expression: sensing oxidative phosphorylation status and glycolytic rate. J. Biol. Chem. 2010 Aug;285(33):25822-30
  Yu FX et al
  2010/01/01
  
• 備考：
  Species: Human
• 参照：
  

• No.： 64
• 文献情報：
  Marmugi A et al. Activation of the Constitutive Androstane Receptor induces hepatic lipogenesis and regulates Pnpla3 gene expression in a LXR-independent way. Toxicol. Appl. Pharmacol. 2016 Jul;303:90-100
  Marmugi A et al
  2016/01/01
  
• 備考：
  
• 参照：
  

• No.： 65
• 文献情報：
  Kitsunai H et al. High glucose induces platelet-derived growth factor-C via carbohydrate response element-binding protein in glomerular mesangial cells. Physiol Rep 2016 Mar;4(6)
  Kitsunai H et al
  2016/01/01
  
• 備考：
  
• 参照：
  

• No.： 66
• 文献情報：
  Zhang Z et al. Berberine prevents progression from hepatic steatosis to steatohepatitis and fibrosis by reducing endoplasmic reticulum stress. Sci Rep 2016;6:20848
  Zhang Z et al
  2016/01/01
  
• 備考：
  
• 参照：
  

• No.： 67
• 文献情報：
  Tang Y et al. Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism. Nat Commun 2016;7:11365
  Tang Y et al
  2016/01/01
  
• 備考：
  
• 参照：
  

• No.： 68
• 文献情報：
  Witte N et al. The Glucose Sensor ChREBP Links De Novo Lipogenesis to PPARγ Activity and Adipocyte Differentiation. Endocrinology 2015 Nov;156(11):4008-19
  Witte N et al
  2015/01/01
  
• 備考：
  
• 参照：
  

• No.： 69
• 文献情報：
  Chelimo K et al. Age-related differences in naturally acquired T cell memory to Plasmodium falciparum merozoite surface protein 1. PLoS ONE 2011;6(9):e24852
  Chelimo K et al
  2011/01/01
  
• 備考：
  
• 参照：
  

• No.： 70
• 文献情報：
  Miller SD et al. Reduced impact logging minimally alters tropical rainforest carbon and energy exchange. Proc. Natl. Acad. Sci. U.S.A. 2011 Nov;108(48):19431-5
  Miller SD et al
  2011/01/01
  
• 備考：
  
• 参照：
  

• No.： 71
• 文献情報：
  Krishnamoorthy N et al. Activation of c-Kit in dendritic cells regulates T helper cell differentiation and allergic asthma. Nat. Med. 2008 May;14(5):565-73
  Krishnamoorthy N et al
  2008/01/01
  
• 備考：
  
• 参照：
  

• No.： 72
• 文献情報：
  Trabelsi MS et al. Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L cells. Nat Commun 2015;6:7629
  Trabelsi MS et al
  2015/01/01
  
• 備考：
  
• 参照：
  

• No.： 73
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  Species: Mouse, Applications: WB
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• No.： 76
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  Sanchez-Gurmaches J et al. Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis. Cell Metab. 2018 Jan;27(1):195-209.e6
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• No.： 77
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  Janssens S et al. An In Vivo Magnetic Resonance Spectroscopy Study of the Effects of Caloric and Non-Caloric Sweeteners on Liver Lipid Metabolism in Rats. Nutrients 2017 May;9(5)
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  Species: Rat, Applications: WB
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• No.： 78
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  Singh KB et al. Prostate cancer chemoprevention by sulforaphane in a preclinical mouse model is associated with inhibition of fatty acid metabolism. Carcinogenesis 2018 May;39(6):826-837
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• No.： 79
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  Schmidt SF et al. Integrative Genomics Outlines a Biphasic Glucose Response and a ChREBP-RORγ Axis Regulating Proliferation in β Cells. Cell Rep 2016 08;16(9):2359-72
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  Species: Human, Applications: ChIP
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• No.： 80
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  Harris K et al. The effects of prenatal metformin on obesogenic diet-induced alterations in maternal and fetal fatty acid metabolism. Nutr Metab (Lond) 2016;13(1):55
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  Species: Rat, Applications: WB
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• No.： 81
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  Species: Rat, Applications: ChIP
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• No.： 82
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  Bricambert J et al. The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity. Nat Commun 2018 05;9(1):2092
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  Species: Mouse, Applications: WB
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• No.： 83
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  Linden AG et al. Interplay between ChREBP and SREBP-1c coordinates postprandial glycolysis and lipogenesis in livers of mice. J. Lipid Res. 2018 03;59(3):475-487
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  Species: Mouse, Applications: WB
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• No.： 84
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  Fan Q et al. LXRα Regulates Hepatic ChREBPα Activity and Lipogenesis upon Glucose, but Not Fructose Feeding in Mice. Nutrients 2017 Jun;9(7)
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  Species: Mouse, Applications: WB
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• No.： 85
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  Kim YS et al. Aralia elata (Miq) Seem Extract Decreases O-GlcNAc Transferase Expression and Retinal Cell Death in Diabetic Mice. J Med Food 2017 Oct;20(10):989-1001
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  Species: Mouse, Applications: WB
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  Cho JH et al. Downregulation of SIRT1 signaling underlies hepatic autophagy impairment in glycogen storage disease type Ia. PLoS Genet. 2017 May;13(5):e1006819
  Cho JH et al
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  Species: Mouse, Applications: IHC-P
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• No.： 87
• 文献情報：
  Cao W et al. Dual effects of fructose on ChREBP and FoxO1/3α are responsible for AldoB up-regulation and vascular remodelling. Clin. Sci. 2017 02;131(4):309-325
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  WB
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  Kumar A et al. Activation of Nrf2 Is Required for Normal and ChREBPα-Augmented Glucose-Stimulated β-Cell Proliferation. Diabetes 2018 08;67(8):1561-1575
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  Species: Human, Applications:
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• No.： 89
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  Kim MS et al. ChREBP regulates fructose-induced glucose production independently of insulin signaling. J. Clin. Invest. 2016 11;126(11):4372-4386
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  Species: Mouse, Applications: WB
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• No.： 90
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  Na TY et al. The trisaccharide raffinose modulates epidermal differentiation through activation of liver X receptor. Sci Rep 2017 03;7:43823
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  Species: Human, Applications: ChIP
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• No.： 91
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  Iroz A et al. A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 Response. Cell Rep 2017 Oct;21(2):403-416
  Iroz A et al
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  Species: Mouse, Applications: ChIP
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• No.： 92
• 文献情報：
  Softic S et al. Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling. J. Clin. Invest. 2017 Nov;127(11):4059-4074
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  Species: Mouse, Applications: WB
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• No.： 93
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  Kwon JH et al. Liver-directed gene therapy for murine glycogen storage disease type Ib. Hum. Mol. Genet. 2017 11;26(22):4395-4405
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• No.： 94
• 文献情報：
  Kim M et al. Intestinal, but not hepatic, ChREBP is required for fructose tolerance. JCI Insight 2017 Dec;2(24)
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  Species: Mouse, Applications: ChIP, WB
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• No.： 95
• 文献情報：
  Heidenreich S et al. Retinol saturase coordinates liver metabolism by regulating ChREBP activity. Nat Commun 2017 08;8(1):384
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• No.： 96
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  Kim YS et al. Metformin protects against retinal cell death in diabetic mice. Biochem. Biophys. Res. Commun. 2017 10;492(3):397-403
  Kim YS et al
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• No.： 99
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  Long J et al. Role for carbohydrate response element-binding protein (ChREBP) in high glucose-mediated repression of long noncoding RNA Tug1. J Biol Chem 2020 11;295(47):15840-15852
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• No.： 100
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  Lei Y et al. Carbohydrate response element binding protein (ChREBP) correlates with colon cancer progression and contributes to cell proliferation. Sci Rep 2020 03;10(1):4233
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• No.： 101
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  McMurphy TB et al. Hepatic Expression of Adenovirus 36 E4ORF1 Improves Glycemic Control and Promotes Glucose Metabolism Through AKT Activation. Diabetes 2017 02;66(2):358-371
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  Tong X et al. DDB1 E3 ligase controls dietary fructose-induced ChREBPα stabilization and liver steatosis via CRY1. Metabolism 2020 06;107:154222
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• No.： 104
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  Bagchi DP et al. Wntless regulates lipogenic gene expression in adipocytes and protects against diet-induced metabolic dysfunction. Mol Metab 2020 09;39:100992
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  Youn DY et al. The Mediator complex kinase module is necessary for fructose regulation of liver glycogen levels through induction of glucose-6-phosphatase catalytic subunit (G6pc). Mol Metab 2021 06;48:101227
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  Vel叩zquez-Villegas L et al. ChREBP downregulates SNAT2 amino acid transporter expression through interactions with SMRT in response to a high-carbohydrate diet. Am J Physiol Endocrinol Metab 2021 01;320(1):E102-E112
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  Liu Y et al. Hyperlipidemic hypersensitivity to lethal microbial inflammation and its reversal by selective targeting of nuclear transport shuttles. Sci Rep 2021 Jun;11(1):11907
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• No.： 114
• 文献情報：
  Heidenreich S et al. The glucose-sensing transcription factor ChREBP is targeted by proline hydroxylation. J Biol Chem 2020 12;295(50):17158-17168
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  Chen N et al. ChREBP deficiency alleviates apoptosis by inhibiting TXNIP/oxidative stress in diabetic nephropathy. J Diabetes Complications 2021 Dec;35(12):108050
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