Anti-XCT, Rabbit-Poly

データシート

• 商品コード：NB300-318
• メーカー：NOV
• 包装：0.1ml
• 価格： ¥110,000
• 在庫：無(未発注)

マイリストに追加 マイリストに追加済

• No.： 1
• 文献情報：
  Liu R et al. Cystine-glutamate transporter SLC7A11 mediates resistance to geldanamycin but not to 17-(allylamino)-17-demethoxygeldanamycin. Mol. Pharmacol. 2007 Dec;72(6):1637-46
  Liu R et al
  2007/01/01
  
• 備考：
  
• 参照：
  

• No.： 2
• 文献情報：
  Langford MP et al. Glutamate, excitatory amino acid transporters, Xc- antiporter, glutamine synthetase, and gamma-glutamyltranspeptidase in human corneal epithelium. Curr. Eye Res. 2010 Mar;35(3):202-11
  Langford MP et al
  2010/01/01
  
• 備考：
  
• 参照：
  

• No.： 3
• 文献情報：
  Levring TB et al. Activated human CD4 T cells express transporters for both cysteine and cystine. Sci Rep 2012;2:266
  Levring TB et al
  2012/01/01
  
• 備考：
  
• 参照：
  

• No.： 4
• 文献情報：
  Zhang L et al. Role of the Nrf2-ARE pathway in acrylamide neurotoxicity. Toxicol. Lett. 2011 Aug;205(1):1-7
  Zhang L et al
  2011/01/01
  
• 備考：
  Applications: WB, Species: Rat
• 参照：
  

• No.： 5
• 文献情報：
  Ferrucci A et al. Extracellular human immunodeficiency virus type 1 viral protein R causes reductions in astrocytic ATP and glutathione levels compromising the antioxidant reservoir. Virus Res. 2012 Aug;167(2):358-69
  Ferrucci A et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ICC, IF
• 参照：
  

• No.： 6
• 文献情報：
  Garg SK et al. Astrocytic redox remodeling by amyloid beta peptide. Antioxid. Redox Signal. 2011 Jun;14(12):2385-97
  Garg SK et al
  2011/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 7
• 文献情報：
  Tsai W et al. Early intraarticular injection of hyaluronic acid attenuates osteoarthritis progression in anterior cruciate ligament-transected rats. Connect. Tissue Res. 2012 Sep;
  Tsai W et al
  2012/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 8
• 文献情報：
  Baek S et al. Exploratory clinical trial of (4S)-4-(3-[18F]fluoropropyl)-L-glutamate for imaging xC- transporter using positron emission tomography in patients with non-small cell lung or breast cancer. Clin. Cancer Res. 2012 Oct;18(19):5427-37
  Baek S et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: IHC
• 参照：
  

• No.： 9
• 文献情報：
  Balza E et al. The pharmacologic inhibition of the xc- antioxidant system improves the antitumor efficacy of COX inhibitors in the in vivo model of 3-MCA tumorigenesis. Carcinogenesis 2013 Mar;34(3):620-6
  Balza E et al
  2013/01/01
  
• 備考：
  
• 参照：
  

• No.： 10
• 文献情報：
  Baek S et al. (4S)-4-(3-18F-fluoropropyl)-L-glutamate for imaging of xC transporter activity in hepatocellular carcinoma using PET: preclinical and exploratory clinical studies. J. Nucl. Med. 2013 Jan;54(1):117-23
  Baek S et al
  2013/01/01
  
• 備考：
  
• 参照：
  

• No.： 11
• 文献情報：
  Wengrod J et al. Inhibition of nonsense-mediated RNA decay activates autophagy. Mol. Cell. Biol. 2013 Jun;33(11):2128-35
  Wengrod J et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 12
• 文献情報：
  D'Elia M et al. Burn injury induces the expression of cystine/glutamate transporter (x(c)(-)) in mouse T cells. Immunol. Lett. 2009 Aug;125(2):137-44
  D'Elia M et al
  2009/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 13
• 文献情報：
  Pei S et al. Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells. J. Biol. Chem. 2013 Nov;288(47):33542-58
  Pei S et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 14
• 文献情報：
  Timmerman LA et al. Glutamine sensitivity analysis identifies the xCT antiporter as a common triple-negative breast tumor therapeutic target. Cancer Cell 2013 Oct;24(4):450-65
  Timmerman LA et al
  2013/01/01
  
• 備考：
  
• 参照：
  

• No.： 15
• 文献情報：
  Martin L et al. Stress-induced inhibition of nonsense-mediated RNA decay regulates intracellular cystine transport and intracellular glutathione through regulation of the cystine/glutamate exchanger SLC7A11. Oncogene 2014 Nov;
  Martin L et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 16
• 文献情報：
  Fontana JM et al. Kaposi's Sarcoma-Associated Herpesvirus Subversion of the Anti-Inflammatory Response in Human Skin Cells Reveals Correlates of Latency and Disease Pathogenesis. J Skin Cancer 2014;2014:246076
  Fontana JM et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 17
• 文献情報：
  Drayton RM et al. Reduced expression of miRNA-27a modulates cisplatin resistance in bladder cancer by targeting the cystine/glutamate exchanger SLC7A11. Clin. Cancer Res. 2014 Apr;20(7):1990-2000
  Drayton RM et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 18
• 文献情報：
  Yang Y et al. IGF-I regulates redox status in breast cancer cells by activating the amino acid transport molecule xC-. Cancer Res. 2014 Apr;74(8):2295-305
  Yang Y et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 19
• 文献情報：
  Aal-Aaboda M et al. Effects of (R)-(-)-5-methyl-1-nicotinoyl-2-pyrazoline on glutamate transporter 1 and cysteine/glutamate exchanger as well as ethanol drinking behavior in male, alcohol-preferring rats. J. Neurosci. Res. 2015 Jan;
  Aal-Aaboda M et al
  2015/01/01
  
• 備考：
  Species: Rat, Applications: WB
• 参照：
  

• No.： 20
• 文献情報：
  Rao PS et al. Effects of ceftriaxone on GLT1 isoforms, xCT and associated signaling pathways in P rats exposed to ethanol. Psychopharmacology (Berl.) 2015 Jan;
  Rao PS et al
  2015/01/01
  
• 備考：
  Species: Rat, Applications: WB
• 参照：
  

• No.： 21
• 文献情報：
  Merckx E et al. Lack of effect of Theiler's murine encephalomyelitis virus infection on system xc⁻. Neurosci. Lett. 2015 Apr;593:124-8
  Merckx E et al
  2015/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 22
• 文献情報：
  Boutter J et al. Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support. Oncotarget 2014 Nov;5(22):11501-12
  Boutter J et al
  2014/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 23
• 文献情報：
  Lu H et al. Chemotherapy triggers HIF-1-dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype. Proc. Natl. Acad. Sci. U.S.A. 2015 Aug;112(33):E4600-9
  Lu H et al
  2015/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 24
• 文献情報：
  Pati D et al. Alcohol consumption increases basal extracellular glutamate in the nucleus accumbens core of Sprague-Dawley rats without increasing spontaneous glutamate release. Eur. J. Neurosci. 2016 Jul;44(2):1896-905
  Pati D et al
  2016/01/01
  
• 備考：
  
• 参照：
  

• No.： 25
• 文献情報：
  Van Liefferinge J et al. Comparative analysis of antibodies to xCT (Slc7a11): Forewarned is forearmed. J. Comp. Neurol. 2016 Apr;524(5):1015-32
  Van Liefferinge J et al
  2016/01/01
  
• 備考：
  
• 参照：
  

• No.： 26
• 文献情報：
  LaCrosse AL et al. Contrasting the Role of xCT and GLT-1 Upregulation in the Ability of Ceftriaxone to Attenuate the Cue-Induced Reinstatement of Cocaine Seeking and Normalize AMPA Receptor Subunit Expression. J. Neurosci. 2017 06;37(24):5809-5821
  LaCrosse AL et al
  2017/01/01
  
• 備考：
  Species: Rat, Applications: WB
• 参照：
  

• No.： 27
• 文献情報：
  Bechard AR et al. The effects of ceftriaxone on cue-primed reinstatement of cocaine-seeking in male and female rats: estrous cycle effects on behavior and protein expression in the nucleus accumbens. Psychopharmacology (Berl.) 2018 03;235(3):837-848
  Bechard AR et al
  2018/01/01
  
• 備考：
  Species: Rat, Applications: WB
• 参照：
  

• No.： 28
• 文献情報：
  Linher-Melville K et al. Chronic Inhibition of STAT3/STAT5 in Treatment-Resistant Human Breast Cancer Cell Subtypes: Convergence on the ROS/SUMO Pathway and Its Effects on xCT Expression and System xc- Activity. PLoS ONE 2016;11(8):e0161202
  Linher-Melville K et al
  2016/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 29
• 文献情報：
  Merckx E et al. Absence of system x_c^- on immune cells invading the central nervous system alleviates experimental autoimmune encephalitis. J Neuroinflammation 2017 01;14(1):9
  Merckx E et al
  2017/01/01
  
• 備考：
  
• 参照：
  

• No.： 30
• 文献情報：
  Hoehne A et al. [¹⁸F]FSPG-PET reveals increased cystine/glutamate antiporter (xc-) activity in a mouse model of multiple sclerosis. J Neuroinflammation 2018 Feb;15(1):55
  Hoehne A et al
  2018/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 31
• 文献情報：
  Miladinovic T et al. Functional effects of TrkA inhibition on system x_C^--mediated glutamate release and cancer-induced bone pain. Mol Pain ;14:1744806918776467
  Miladinovic T et al
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 32
• 文献情報：
  Polewski MD et al. Increased Expression of System xc- in Glioblastoma Confers an Altered Metabolic State and Temozolomide Resistance. Mol. Cancer Res. 2016 12;14(12):1229-1242
  Polewski MD et al
  2016/01/01
  
• 備考：
  
• 参照：
  

• No.： 33
• 文献情報：
  Slosky LM et al. The cystine/glutamate antiporter system xc- drives breast tumor cell glutamate release and cancer-induced bone pain. Pain 2016 11;157(11):2605-2616
  Slosky LM et al
  2016/01/01
  
• 備考：
  Species: Mouse, Applications:
• 参照：
  

• No.： 34
• 文献情報：
  Bertaux-Skeirik N et al. CD44 variant isoform 9 emerges in response to injury and contributes to the regeneration of the gastric epithelium. J. Pathol. 2017 Aug;242(4):463-475
  Bertaux-Skeirik N et al
  2017/01/01
  
• 備考：
  Species: Human, Applications:
• 参照：
  

• No.： 35
• 文献情報：
  Kavanaugh G et al. Utility of [¹⁸F]FSPG PET to Image Hepatocellular Carcinoma: First Clinical Evaluation in a US Population. Mol Imaging Biol 2016 12;18(6):924-934
  Kavanaugh G et al
  2016/01/01
  
• 備考：
  IHC
• 参照：
  

• No.： 36
• 文献情報：
  Su叩rez-Pozos E et al. Characterization of the cystine/glutamate antiporter in cultured Bergmann glia cells. Neurochem. Int. 2017 Sep;108:52-59
  Su叩rez-Pozos E et al
  2017/01/01
  
• 備考：
  WB
• 参照：
  

• No.： 37
• 文献情報：
  Sayin VI et al. Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer. Elife 2017 10;6
  Sayin VI et al
  2017/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 38
• 文献情報：
  Martin C et al. Erythropoietin-induced cytoprotection in intestinal epithelial cells is linked to system Xc<sup/>. Exp. Cell Res. 2017 03;352(2):202-206
  Martin C et al
  2017/01/01
  
• 備考：
  
• 参照：
  

• No.： 39
• 文献情報：
  Nasca C et al. Role of the Astroglial Glutamate Exchanger xCT in Ventral Hippocampus in Resilience to Stress. Neuron 2017 Oct;96(2):402-413.e5
  Nasca C et al
  2017/01/01
  
• 備考：
  Species: Mouse, Applications:
• 参照：
  

• No.： 40
• 文献情報：
  Soria FN et al. Cystine/glutamate antiporter blockage induces myelin degeneration. Glia 2016 08;64(8):1381-95
  Soria FN et al
  2016/01/01
  
• 備考：
  
• 参照：
  

• No.： 41
• 文献情報：
  Park SY et al. Clinical Evaluation of (4S)-4-(3-[¹⁸F]Fluoropropyl)-L-glutamate (¹⁸F-FSPG) for PET/CT Imaging in Patients with Newly Diagnosed and Recurrent Prostate Cancer. Clin Cancer Res 2020 10;26(20):5380-5387
  Park SY et al
  2020/01/01
  
• 備考：
  
• 参照：
  

• No.： 42
• 文献情報：
  Krys D et al. PET Imaging of L-Type Amino Acid Transporter (LAT1) and Cystine-Glutamate Antiporter (x_c^-) with [¹⁸F]FDOPA and [¹⁸F]FSPG in Breast Cancer Models. Mol Imaging Biol 2020 12;22(6):1562-1571
  Krys D et al
  2020/01/01
  
• 備考：
  
• 参照：
  

• No.： 43
• 文献情報：
  Pitman KE et al. Influx rate of ¹⁸F-fluoroaminosuberic acid reflects cystine/glutamate antiporter expression in tumour xenografts. Eur J Nucl Med Mol Imaging 2019 Sep;46(10):2190-2198
  Pitman KE et al
  2019/01/01
  
• 備考：
  
• 参照：
  

• No.： 44
• 文献情報：
  Wu WC et al. Immunosuppressive Immature Myeloid Cell Generation Is Controlled by Glutamine Metabolism in Human Cancer. Cancer Immunol Res 2019 Oct;7(10):1605-1618
  Wu WC et al
  2019/01/01
  
• 備考：
  
• 参照：
  

• No.： 45
• 文献情報：
  Gao M et al. xCT regulates redox homeostasis and promotes photoreceptor survival after retinal detachment. Free Radic Biol Med 2020 10;158:32-43
  Gao M et al
  2020/01/01
  
• 備考：
  
• 参照：
  

• No.： 46
• 文献情報：
  Long Y et al. Dysregulation of Glutamate Transport Enhances Treg Function That Promotes VEGF Blockade Resistance in Glioblastoma. Cancer Res 2020 02;80(3):499-509
  Long Y et al
  2020/01/01
  
• 備考：
  
• 参照：
  

• No.： 47
• 文献情報：
  Kazama M et al. Astrocytes release glutamate via cystine/glutamate antiporter upregulated in response to increased oxidative stress related to sporadic amyotrophic lateral sclerosis. Neuropathology 2020 Dec;40(6):587-598
  Kazama M et al
  2020/01/01
  
• 備考：
  
• 参照：
  

• No.： 48
• 文献情報：
  Logan CN et al. Nucleus accumbens GLT-1a overexpression reduces glutamate efflux during reinstatement of cocaine-seeking but is not sufficient to attenuate reinstatement. Neuropharmacology 2018 06;135:297-307
  Logan CN et al
  2018/01/01
  
• 備考：
  
• 参照：
  

• No.： 49
• 文献情報：
  Healey KL et al. Effects of adolescent intermittent ethanol on hippocampal expression of glutamate homeostasis and astrocyte-neuronal tethering proteins in male and female rats. J Neurosci Res 2021 Aug;99(8):1908-1921
  Healey KL et al
  2021/01/01
  
• 備考：
  
• 参照：
  

• No.： 50
• 文献情報：
  Zhao X et al. SLC7A11 Reduces Laser-Induced Choroidal Neovascularization by Inhibiting RPE Ferroptosis and VEGF Production. Front Cell Dev Biol 2021;9:639851
  Zhao X et al
  2021/01/01
  
• 備考：
  
• 参照：
  

• No.： 51
• 文献情報：
  Ku CC et al. Deletion of Jdp2 enhances Slc7a11 expression in Atoh-1 positive cerebellum granule cell progenitors in vivo. Stem Cell Res Ther 2021 06;12(1):369
  Ku CC et al
  2021/01/01
  
• 備考：
  
• 参照：
  

• No.： 52
• 文献情報：
  Kim S et al. Characterization of ferroptosis in kidney tubular cell death under diabetic conditions. Cell Death Dis 2021 02;12(2):160
  Kim S et al
  2021/01/01
  
• 備考：
  
• 参照：
  

• No.： 53
• 文献情報：
  Greenwood HE et al. Measurement of Tumor Antioxidant Capacity and Prediction of Chemotherapy Resistance in Preclinical Models of Ovarian Cancer by Positron Emission Tomography. Clin. Cancer Res. 2019 Apr;25(8):2471-2482
  Greenwood HE et al
  2019/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 54
• 文献情報：
  Mi DJ et al. Altered glutamate clearance in ascorbate deficient mice increases seizure susceptibility and contributes to cognitive impairment in APP/PSEN1 mice. Neurobiol. Aging 2018 11;71:241-254
  Mi DJ et al
  2018/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 55
• 文献情報：
  Isobe S et al. Endothelial-Mesenchymal Transition Drives Expression of CD44 Variant and xCT in Pulmonary Hypertension. Am. J. Respir. Cell Mol. Biol. 2019 Mar;
  Isobe S et al
  2019/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 56
• 文献情報：
  Ungard RG et al. xCT knockdown in human breast cancer cells delays onset of cancer-induced bone pain. Mol Pain ;15:1744806918822185
  Ungard RG et al
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 57
• 文献情報：
  Li C et al. mTOR-dependent upregulation of xCT blocks melanin synthesis and promotes tumorigenesis. Cell Death Differ. 2019 Feb;
  Li C et al
  2019/01/01
  
• 備考：
  Species: Rat, Applications: WB
• 参照：