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在庫・価格 : 2024年04月26日 02時19分 現在

商品名 商品コード メーカー 包装 価格 在庫 リスト
Anti-PINK1, Rabbit-Poly <Anti-PTEN Induced Putative Kinase Protein 1>
データシート
BC100-494 NOVノバス バイオロジカルス
Novus biologicals, LLC
0.1 ml ¥103,000 1個 追加

在庫・価格 : 2024年04月26日 02時19分 現在

Anti-PINK1, Rabbit-Poly <Anti-PTEN Induced Putative Kinase Protein 1>

  • 商品コード:BC100-494
  • メーカー:NOV
  • 包装:0.1ml
  • 価格: ¥103,000
  • 在庫:1個
使用文献
No. 文献情報 備考 参照
1 Qi Z et al. Loss of PINK1 function decreases PP2A activity and promotes autophagy in dopaminergic cells and a murine model. Neurochem. Int. 2011 Oct;59(5):572-81
Qi Z et al
2011/01/01
PubMed
2 Cui M et al. Perturbations in mitochondrial dynamics induced by human mutant PINK1 can be rescued by the mitochondrial division inhibitor mdivi-1. J. Biol. Chem. 2010 Apr;285(15):11740-52
Cui M et al
2010/01/01
PubMed
3 Liu W et al. PINK1 defect causes mitochondrial dysfunction, proteasomal deficit and alpha-synuclein aggregation in cell culture models of Parkinson&quot;s disease. PLoS ONE 2009;4(2):e4597
Liu W et al
2009/01/01
PubMed
4 Weihofen A et al. Pink1 Parkinson mutations, the Cdc37/Hsp90 chaperones and Parkin all influence the maturation or subcellular distribution of Pink1. Hum. Mol. Genet. 2008 Feb;17(4):602-16
Weihofen A et al
2008/01/01
PubMed
5 Cui J et al. Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family. Science 2010 Sep;329(5996):1215-8
Cui J et al
2010/01/01
PubMed
6 Meissner C et al. The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking. J. Neurochem. 2011 Jun;117(5):856-67
Meissner C et al
2011/01/01
PubMed
7 Zhou C et al. The kinase domain of mitochondrial PINK1 faces the cytoplasm. Proc. Natl. Acad. Sci. U.S.A. 2008 Aug;105(33):12022-7
Zhou C et al
2008/01/01
PubMed
8 Exner N et al. Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin. J. Neurosci. 2007 Nov;27(45):12413-8
Exner N et al
2007/01/01
PubMed
9 Puccetti L et al. Evaluation of the effectiveness and safety of etodolac in prolonged treatment of active osteoarthritis. Int J Clin Pharmacol Res 1991;11(3):143-58
Puccetti L et al
1991/01/01
PubMed
10 Kondapalli C et al. PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65. Open Biol 2012 May;2(5):120080
Kondapalli C et al
2012/01/01
Species: Human, Applications: WB PubMed
11 Okatsu K et al. PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria. Nat Commun 2012 Aug;3:1016
Okatsu K et al
2012/01/01
Species: Human, Mouse, Applications: WB, ICC/IF PubMed
12 Mitsuhashi S et al. Muscle choline kinase beta defect causes mitochondrial dysfunction and increased mitophagy. Hum. Mol. Genet. 2011 Oct;20(19):3841-51
Mitsuhashi S et al
2011/01/01
Applications: IHC, ICC/IF PubMed
13 Sekine S et al. Rhomboid protease PARL mediates the mitochondrial membrane potential loss-induced cleavage of PGAM5. J. Biol. Chem. 2012 Oct;287(41):34635-45
Sekine S et al
2012/01/01
PubMed
14 Lin W et al. Characterization of PINK1 processing, stability, and subcellular localization. J. Neurochem. 2008 Jul;106(1):464-74
Lin W et al
2008/01/01
Species: Human, Applications: WB PubMed
15 Song S et al. Characterization of PINK1 (PTEN-induced putative kinase 1) mutations associated with Parkinson disease in mammalian cells and Drosophila. J. Biol. Chem. 2013 Feb;288(8):5660-72
Song S et al
2013/01/01
Species: Human, Applications: ICC/IF, WB PubMed
16 Shiba-Fukushima K et al. PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy. Sci Rep 2012;2:1002
Shiba-Fukushima K et al
2012/01/01
Species: Mouse, Applications: WB PubMed
17 Wood-Kaczmar A et al. The role of the mitochondrial NCX in the mechanism of neurodegeneration in Parkinson&quot;s disease. Adv. Exp. Med. Biol. 2013;961:241-9
Wood-Kaczmar A et al
2013/01/01
Species: Human, Applications: ICC/IF PubMed
18 Irrcher I et al. Loss of the Parkinson&quot;s disease-linked gene DJ-1 perturbs mitochondrial dynamics. Hum. Mol. Genet. 2010 Oct;19(19):3734-46
Irrcher I et al
2010/01/01
Species: Mouse, Applications: WB PubMed
19 Geisler S et al. The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations. Autophagy 2010 Oct;6(7):871-8
Geisler S et al
2010/01/01
Species: Human, Applications: WB PubMed
20 Saita S et al. Selective escape of proteins from the mitochondria during mitophagy. Nat Commun 2013;4:1410
Saita S et al
2013/01/01
Species: Mouse, Applications: WB PubMed
21 Gegg ME et al. Silencing of PINK1 expression affects mitochondrial DNA and oxidative phosphorylation in dopaminergic cells. PLoS ONE 2009;4(3):e4756
Gegg ME et al
2009/01/01
Species: Human, Applications: WB PubMed
22 Narendra DP et al. PINK1 rendered temperature sensitive by disease-associated and engineered mutations. Hum. Mol. Genet. 2013 Jul;22(13):2572-89
Narendra DP et al
2013/01/01
Species: Human, Applications: WB PubMed
23 Koyano F et al. The principal PINK1 and Parkin cellular events triggered in response to dissipation of mitochondrial membrane potential occur in primary neurons. Genes Cells 2013 Aug;18(8):672-81
Koyano F et al
2013/01/01
Species: Mouse, Applications: WB PubMed
24 Hoshino A et al. Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart. Nat Commun 2013 Aug;4:2308
Hoshino A et al
2013/01/01
Species: Mouse, Applications: WB PubMed
25 Iguchi M et al. Parkin-catalyzed ubiquitin-ester transfer is triggered by PINK1-dependent phosphorylation. J. Biol. Chem. 2013 Jul;288(30):22019-32
Iguchi M et al
2013/01/01
Species: Mouse, Applications: WB PubMed
26 Murata H et al. SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria. Mol. Biol. Cell 2013 Sep;24(18):2772-84
Murata H et al
2013/01/01
Species: Human, Applications: WB PubMed
27 Becker D et al. Pink1 kinase and its membrane potential (Delta&#x3C8;)-dependent cleavage product both localize to outer mitochondrial membrane by unique targeting mode. J. Biol. Chem. 2012 Jun;287(27):22969-87
Becker D et al
2012/01/01
Species: Human, Applications: WB, ICC/IF PubMed
28 Holmstrom K. The Influence of the PD-associated Gene Products PINK1 and HtrA2/Omi on Mitochondrial Integrity Dissertation http://nbn-resolving.de/urn:nbn:de:bsz:21-opus-48153 2010 May 21 (WB, Human)

Species: Human, Applications: WB PubMed
29 Imai Y et al. The loss of PGAM5 suppresses the mitochondrial degeneration caused by inactivation of PINK1 in Drosophila. PLoS Genet. 2010;6(12):e1001229
Imai Y et al
2010/01/01
Species: Human, Applications: WB, ICC/IF PubMed
30 Wang X et al. PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility. Cell 2011 Nov;147(4):893-906
Wang X et al
2011/01/01
Species: Human, Applications: WB, IP PubMed
31 Kamp F et al. Inhibition of mitochondrial fusion by &#x3B1;-synuclein is rescued by PINK1, Parkin and DJ-1. EMBO J. 2010 Oct;29(20):3571-89
Kamp F et al
2010/01/01
Species: Human, Applications: WB PubMed
32 Zhou ZD et al. Mutant PINK1 upregulates tyrosine hydroxylase and dopamine levels, leading to vulnerability of dopaminergic neurons. Free Radic. Biol. Med. 2014 Mar;68:220-33
Zhou ZD et al
2014/01/01
PubMed
33 Okatsu K et al. A dimeric PINK1-containing complex on depolarized mitochondria stimulates Parkin recruitment. J. Biol. Chem. 2013 Dec;288(51):36372-84
Okatsu K et al
2013/01/01
PubMed
34 Dagda RK et al. Beyond the mitochondrion: cytosolic PINK1 remodels dendrites through Protein Kinase A. J. Neurochem. 2014 Mar;128(6):864-77
Dagda RK et al
2014/01/01
PubMed
35 Yamano K et al. PINK1 is degraded through the N-end rule pathway. Autophagy 2013 Nov;9(11):1758-69
Yamano K et al
2013/01/01
PubMed
36 Montaigne D et al. Myocardial contractile dysfunction is associated with impaired mitochondrial function and dynamics in type 2 diabetic but not in obese patients. Circulation 2014 Aug;130(7):554-64
Montaigne D et al
2014/01/01
Species: Human, Applications: WB PubMed
37 G坦mez-S叩nchez R et al. Mitochondrial impairment increases FL-PINK1 levels by calcium-dependent gene expression. Neurobiol. Dis. 2014 Feb;62:426-40
G坦mez-S叩nchez R et al
2014/01/01
Species: Human, Applications: WB, ICC/IF PubMed
38 Lee S et al. Role of Glucose Metabolism and ATP in Maintaining PINK1 Levels during Parkin-mediated Mitochondrial Damage Responses. J. Biol. Chem. 2015 Jan;290(2):904-17
Lee S et al
2015/01/01
Species: Human, Mouse, Applications: WB PubMed
39 McLelland GL et al. Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control. EMBO J. 2014 Feb;33(4):282-95
McLelland GL et al
2014/01/01
Species: Human, Applications: WB PubMed
40 Shiba-Fukushima K et al. Lysine 63-linked polyubiquitination is dispensable for Parkin-mediated mitophagy. J. Biol. Chem. 2014 Nov;289(48):33131-6
Shiba-Fukushima K et al
2014/01/01
Species: Human, Applications: WB PubMed
41 Patil KS et al. PARK13 regulates PINK1 and subcellular relocation patterns under oxidative stress in neurons. J. Neurosci. Res. 2014 Sep;92(9):1167-77
Patil KS et al
2014/01/01
Species: Human, Applications: Wb PubMed
42 Mizumura K et al. Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD. J. Clin. Invest. 2014 Sep;124(9):3987-4003
Mizumura K et al
2014/01/01
Species: Human, Applications: IHC-P PubMed
43 Parganlija D et al. Loss of PINK1 impairs stress-induced autophagy and cell survival. PLoS ONE 2014;9(4):e95288
Parganlija D et al
2014/01/01
Species: Human, Applications: WB PubMed
44 Kane LA et al. PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity. J. Cell Biol. 2014 Apr;205(2):143-53
Kane LA et al
2014/01/01
Species: Human, Applications: WB PubMed
45 Choi HK et al. PINK1 positively regulates HDAC3 to suppress dopaminergic neuronal cell death. Hum. Mol. Genet. 2014 Oct;
Choi HK et al
2014/01/01
Species: Human, Applications: IP PubMed
46 Koyano F et al. Ubiquitin is phosphorylated by PINK1 to activate parkin. Nature 2014 Jun;510(7503):162-6
Koyano F et al
2014/01/01
Species: Human, Mouse, Applications: WB PubMed
47 Grenier K et al. Short mitochondrial ARF triggers Parkin/PINK1-dependent mitophagy. J. Biol. Chem. 2014 Oct;289(43):29519-30
Grenier K et al
2014/01/01
PubMed
48 Shiba-Fukushima K et al. Phosphorylation of mitochondrial polyubiquitin by PINK1 promotes Parkin mitochondrial tethering. PLoS Genet. 2014 Dec;10(12):e1004861
Shiba-Fukushima K et al
2014/01/01
Species: Human, Applications: WB PubMed
49 Bifsha P et al. Rgs6 is required for adult maintenance of dopaminergic neurons in the ventral substantia nigra. PLoS Genet. 2014 Dec;10(12):e1004863
Bifsha P et al
2014/01/01
Species: Mouse, Applications: IHC-P PubMed
50 Aerts L et al. PINK1 kinase catalytic activity is regulated by phosphorylation on serines 228 and 402. J. Biol. Chem. 2015 Jan;290(5):2798-811
Aerts L et al
2015/01/01
Applications: WB PubMed
51 Bueno M et al. PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis. J. Clin. Invest. 2015 Feb;125(2):521-38
Bueno M et al
2015/01/01
Species: Mouse, Applications: WB PubMed
52 Palubinsky AM et al. CHIP Is an Essential Determinant of Neuronal Mitochondrial Stress Signaling. Antioxid. Redox Signal. 2015 Mar;
Palubinsky AM et al
2015/01/01
Species: Mouse, Rat, Applications: WB, ICC/IF PubMed
53 Han JY et al. Nitric Oxide Induction of Parkin Translocation in PTEN-induced Putative Kinase 1 (PINK1) Deficiency: FUNCTIONAL ROLE OF NEURONAL NITRIC OXIDE SYNTHASE DURING MITOPHAGY. J. Biol. Chem. 2015 Apr;290(16):10325-35
Han JY et al
2015/01/01
Species: Human, Applications: WB PubMed
54 Duan X et al. Upregulation of human PINK1 gene expression by NF&#x3BA;B signalling. Mol Brain 2014;7:57
Duan X et al
2014/01/01
Applications: WB PubMed
55 Lim GG et al. Cytosolic PTEN-induced Putative Kinase 1 Is Stabilized by the NF-&#x3BA;B Pathway and Promotes Non-selective Mitophagy. J. Biol. Chem. 2015 Jul;290(27):16882-93
Lim GG et al
2015/01/01
Species: Human, Applications: ICC/IF, IP PubMed
56 Meissner C et al. Intramembrane protease PARL defines a negative regulator of PINK1- and PARK2/Parkin-dependent mitophagy. Autophagy 2015;11(9):1484-98
Meissner C et al
2015/01/01
Species: Human, Applications: WB PubMed
57 Ivankovic D et al. Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy. J. Neurochem. 2015 Oct;
Ivankovic D et al
2015/01/01
PubMed
58 Akabane S et al. Constitutive Activation of PINK1 Protein Leads to Proteasome-mediated and Non-apoptotic Cell Death Independently of Mitochondrial Autophagy. J. Biol. Chem. 2016 Jul;291(31):16162-74
Akabane S et al
2016/01/01
PubMed
59 Kim J et al. miR-27a and miR-27b regulate autophagic clearance of damaged mitochondria by targeting PTEN-induced putative kinase 1 (PINK1). Mol Neurodegener 2016;11(1):55
Kim J et al
2016/01/01
PubMed
60 Mart鱈n-Maestro P et al. PARK2 enhancement is able to compensate mitophagy alterations found in sporadic Alzheimer&quot;s disease. Hum. Mol. Genet. 2016 Feb;25(4):792-806
Mart鱈n-Maestro P et al
2016/01/01
PubMed
61 Qu D et al. BAG2 Gene-mediated Regulation of PINK1 Protein Is Critical for Mitochondrial Translocation of PARKIN and Neuronal Survival. J. Biol. Chem. 2015 Dec;290(51):30441-52
Qu D et al
2015/01/01
PubMed
62 Yue M et al. Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice. Neurobiol. Dis. 2015 Jun;78:172-95
Yue M et al
2015/01/01
PubMed
63 Seillier M et al. Defects in mitophagy promote redox-driven metabolic syndrome in the absence of TP53INP1. EMBO Mol Med 2015 Jun;7(6):802-18
Seillier M et al
2015/01/01
PubMed
64 Peng M et al. Inhibiting cytosolic translation and autophagy improves health in mitochondrial disease. Hum. Mol. Genet. 2015 Sep;24(17):4829-47
Peng M et al
2015/01/01
PubMed
65 Scott TL et al. Polyubiquitination of apurinic/apyrimidinic endonuclease 1 by Parkin. Mol. Carcinog. 2016 May;
Scott TL et al
2016/01/01
PubMed
66 Okatsu K et al. Phosphorylated ubiquitin chain is the genuine Parkin receptor. J. Cell Biol. 2015 Apr;209(1):111-28
Okatsu K et al
2015/01/01
PubMed
67 Srivastava A et al. MKK3 deletion improves mitochondrial quality. Free Radic. Biol. Med. 2015 Oct;87:373-84
Srivastava A et al
2015/01/01
PubMed
68 Park S et al. Pyruvate stimulates mitophagy via PINK1 stabilization. Cell. Signal. 2015 Sep;27(9):1824-30
Park S et al
2015/01/01
PubMed
69 Gelmetti V et al. PINK1 and BECN1 relocalize at mitochondria-associated membranes during mitophagy and promote ER-mitochondria tethering and autophagosome formation. Autophagy 2017 Apr;13(4):654-669
Gelmetti V et al
2017/01/01
Species: Human, Applications: ICC/IF, WB, IP PubMed
70 Zhang C et al. Sorafenib targets the mitochondrial electron transport chain complexes and ATP synthase to activate the PINK1-Parkin pathway and modulate cellular drug response. J. Biol. Chem. 2017 09;292(36):15105-15120
Zhang C et al
2017/01/01
Applications: WB PubMed
71 Orr AL et al. Long-term oral kinetin does not protect against &#x3B1;-synuclein-induced neurodegeneration in rodent models of Parkinson&quot;s disease. Neurochem. Int. 2017 Oct;109:106-116
Orr AL et al
2017/01/01
WB PubMed
72 Li GB et al. Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels. Oncotarget 2017 Feb;8(6):10359-10374
Li GB et al
2017/01/01
Species: Human, Applications: WB PubMed
73 Yoo L et al. The ubiquitin E3 ligase CHIP promotes proteasomal degradation of the serine/threonine protein kinase PINK1 during staurosporine-induced cell death. J. Biol. Chem. 2018 01;293(4):1286-1297
Yoo L et al
2018/01/01
Species: Human, Applications: PubMed
74 Mart鱈n-Maestro P et al. Mitophagy Failure in Fibroblasts and iPSC-Derived Neurons of Alzheimer&quot;s Disease-Associated Presenilin 1 Mutation. Front Mol Neurosci 2017;10:291
Mart鱈n-Maestro P et al
2017/01/01
Species: Human, Applications: PubMed
75 Jin SM et al. The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria. Autophagy 2013 Nov;9(11):1750-7
Jin SM et al
2013/01/01
WB PubMed
76 Sun X et al. Distinct multilevel misregulations of Parkin and PINK1 revealed in cell and animal models of TDP-43 proteinopathy. Cell Death Dis 2018 Sep;9(10):953
Sun X et al
2018/01/01
Species: Drosophila, Applications: WB PubMed
77 Rossin F et al. Transglutaminase 2 ablation leads to mitophagy impairment associated with a metabolic shift towards aerobic glycolysis. Cell Death Differ. 2015 Mar;22(3):408-18
Rossin F et al
2015/01/01
WB PubMed
78 Bartolom辿 A et al. MTORC1 Regulates both General Autophagy and Mitophagy Induction after Oxidative Phosphorylation Uncoupling. Mol. Cell. Biol. 2017 Sep;
Bartolom辿 A et al
2017/01/01
WB PubMed
79 Weihofen A et al. Pink1 forms a multiprotein complex with Miro and Milton, linking Pink1 function to mitochondrial trafficking. Biochemistry 2009 Mar;48(9):2045-52
Weihofen A et al
2009/01/01
WB PubMed
80 Jabir MS et al. Mitochondrial damage contributes to Pseudomonas aeruginosa activation of the inflammasome and is downregulated by autophagy. Autophagy 2015;11(1):166-82
Jabir MS et al
2015/01/01
WB PubMed
81 Wettengel J et al. Harnessing human ADAR2 for RNA repair - Recoding a PINK1 mutation rescues mitophagy. Nucleic Acids Res. 2017 03;45(5):2797-2808
Wettengel J et al
2017/01/01
Species: Human, Applications: IHC PubMed
82 Xiao B et al. Reactive oxygen species trigger Parkin/PINK1 pathway-dependent mitophagy by inducing mitochondrial recruitment of Parkin. J. Biol. Chem. 2017 10;292(40):16697-16708
Xiao B et al
2017/01/01
WB PubMed
83 Lazarou M et al. PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding. J. Cell Biol. 2013 Jan;200(2):163-72
Lazarou M et al
2013/01/01
Species: Human, Applications: WB PubMed
84 Mizumura K et al. Sphingolipid regulation of lung epithelial cell mitophagy and necroptosis during cigarette smoke exposure. FASEB J. 2018 04;32(4):1880-1890
Mizumura K et al
2018/01/01
Species: Mouse, Applications: PubMed
85 Jamil S et al. The small molecule 2-phenylethynesulfonamide induces covalent modification of p53. Biochem. Biophys. Res. Commun. 2017 Jan;482(1):154-158
Jamil S et al
2017/01/01
Species: Human, Applications: WB PubMed
86 Goiran T et al. Nuclear p53-mediated repression of autophagy involves PINK1 transcriptional down-regulation. Cell Death Differ. 2018 May;25(5):873-884
Goiran T et al
2018/01/01
Species: Mouse, Applications: WB PubMed
87 Kravic B et al. In mammalian skeletal muscle, phosphorylation of TOMM22 by protein kinase CSNK2/CK2 controls mitophagy. Autophagy 2018;14(2):311-335
Kravic B et al
2018/01/01
Species: Mouse, Applications: PubMed
88 Ando M et al. The PINK1 p.I368N mutation affects protein stability and ubiquitin kinase activity. Mol Neurodegener 2017 04;12(1):32
Ando M et al
2017/01/01
Species: Human, Applications: WB, ICC/IF PubMed
89 Wai T et al. The membrane scaffold SLP2 anchors a proteolytic hub in mitochondria containing PARL and the i-AAA protease YME1L. EMBO Rep. 2016 12;17(12):1844-1856
Wai T et al
2016/01/01
PubMed
90 Xu Y et al. Cytoprotection against Hypoxic and/or MPP&#x207A; Injury: Effect of &#x3B4;-Opioid Receptor Activation on Caspase 3. Int J Mol Sci 2016 Aug;17(8)
Xu Y et al
2016/01/01
WB PubMed
91 Hawk MA et al. RIPK1-mediated induction of mitophagy compromises the viability of extracellular-matrix-detached cells. Nat. Cell Biol. 2018 Mar;20(3):272-284
Hawk MA et al
2018/01/01
WB PubMed
92 Bueno M et al. ATF3 represses PINK1 gene transcription in lung epithelial cells to control mitochondrial homeostasis. Aging Cell 2018 Apr;17(2)
Bueno M et al
2018/01/01
Species: Mouse, Applications: WB PubMed
93 Basso V et al. Regulation of ER-mitochondria contacts by Parkin via Mfn2. Pharmacol. Res. 2018 Dec;138:43-56
Basso V et al
2018/01/01
Species: Mouse, Applications: WB PubMed
94 Fiesel FC et al. Mitochondrial targeted HSP90 inhibitor Gamitrinib-TPP (G-TPP) induces PINK1/Parkin-dependent mitophagy. Oncotarget 2017 Dec;8(63):106233-106248
Fiesel FC et al
2017/01/01
Species: Human, Applications: WB PubMed
95 Choubey V et al. BECN1 is involved in the initiation of mitophagy: it facilitates PARK2 translocation to mitochondria. Autophagy 2014 Jun;10(6):1105-19
Choubey V et al
2014/01/01
WB PubMed
96 Tang C et al. PINK1-PRKN/PARK2 pathway of mitophagy is activated to protect against renal ischemia-reperfusion injury. Autophagy 2018;14(5):880-897
Tang C et al
2018/01/01
WB PubMed
97 Walsh TG et al. Loss of the mitochondrial kinase PINK1 does not alter platelet function. Sci Rep 2018 Sep;8(1):14377
Walsh TG et al
2018/01/01
Species: Mouse, Applications: WB PubMed
98 Kim H et al. CRISPR-Cas9 Mediated Telomere Removal Leads to Mitochondrial Stress and Protein Aggregation. Int J Mol Sci 2017 Oct;18(10)
Kim H et al
2017/01/01
Species: Human, Applications: WB PubMed
99 Martinez A et al. Quantitative proteomic analysis of Parkin substrates in Drosophila neurons. Mol Neurodegener 2017 04;12(1):29
Martinez A et al
2017/01/01
Species: Human, Applications: WB PubMed
100 Kumar A et al. SESN2 facilitates mitophagy by helping Parkin translocation through ULK1 mediated Beclin1 phosphorylation. Sci Rep 2018 Jan;8(1):615
Kumar A et al
2018/01/01
Species: Human, Applications: WB PubMed
101 Mannam P et al. MKK3 influences mitophagy and is involved in cigarette smoke-induced inflammation. Free Radic. Biol. Med. 2016 12;101:102-115
Mannam P et al
2016/01/01
PubMed
102 Biel TG et al. Mitochondrial dysfunction activates lysosomal-dependent mitophagy selectively in cancer cells. Oncotarget 2018 Jan;9(1):995-1011
Biel TG et al
2018/01/01
Species: Human, Applications: WB PubMed
103 Thomas HE et al. Mitochondrial Complex I Activity Is Required for Maximal Autophagy. Cell Rep 2018 Aug;24(9):2404-2417.e8
Thomas HE et al
2018/01/01
Species: Human, Applications: WB PubMed
104 Callegari S et al. Phospho-ubiquitin-PARK2 complex as a marker for mitophagy defects. Autophagy 2017 Jan;13(1):201-211
Callegari S et al
2017/01/01
PubMed
105 Marcassa E et al. Dual role of USP30 in controlling basal pexophagy and mitophagy. EMBO Rep. 2018 Jul;19(7)
Marcassa E et al
2018/01/01
Species: Human, Applications: PubMed
106 Sorrentino V et al. Enhancing mitochondrial proteostasis reduces amyloid-&#x3B2; proteotoxicity. Nature 2017 12;552(7684):187-193
Sorrentino V et al
2017/01/01
Species: Human, Applications: PubMed
107 Zhang T et al. BNIP3 Protein Suppresses PINK1 Kinase Proteolytic Cleavage to Promote Mitophagy. J. Biol. Chem. 2016 Oct;291(41):21616-21629
Zhang T et al
2016/01/01
IP, ICC/IF PubMed
108 Fiesel FC et al. (Patho-)physiological relevance of PINK1-dependent ubiquitin phosphorylation. EMBO Rep. 2015 Sep;16(9):1114-30
Fiesel FC et al
2015/01/01
WB PubMed
109 Gu X et al. Lead (Pb) induced ATM-dependent mitophagy via PINK1/Parkin pathway. Toxicol. Lett. 2018 Jul;291:92-100
Gu X et al
2018/01/01
WB PubMed
110 Sun Y et al. Beclin-1-Dependent Autophagy Protects the Heart During Sepsis. Circulation 2018 Nov;138(20):2247-2262
Sun Y et al
2018/01/01
Species: Mouse, Applications: PubMed
111 Berezhnov AV et al. Intracellular pH Modulates Autophagy and Mitophagy. J. Biol. Chem. 2016 Apr;291(16):8701-8
Berezhnov AV et al
2016/01/01
PubMed
112 Lin W et al. Structural determinants of PINK1 topology and dual subcellular distribution. BMC Cell Biol. 2010 Nov;11:90
Lin W et al
2010/01/01
PubMed
113 Sato S et al. Induction of PINK1/Parkin-Mediated Mitophagy. Methods Mol. Biol. 2018;1759:9-17
Sato S et al
2018/01/01
PubMed
114 Gu C et al. Salidroside Ameliorates Mitochondria-Dependent Neuronal Apoptosis after Spinal Cord Ischemia-Reperfusion Injury Partially through Inhibiting Oxidative Stress and Promoting Mitophagy. Oxid Med Cell Longev 2020;2020:3549704
Gu C et al
2020/01/01
PubMed
115 Nikolaou PE et al. Chronic Empagliflozin Treatment Reduces Myocardial Infarct Size in Nondiabetic Mice Through STAT-3-Mediated Protection on Microvascular Endothelial Cells and Reduction of Oxidative Stress. Antioxid Redox Signal 2021 03;34(7):551-571
Nikolaou PE et al
2021/01/01
PubMed
116 Huang YF et al. The protective effort of GPCR kinase 2-interacting protein-1 in neurons via promoting Beclin1-Parkin induced mitophagy at the early stage of spinal cord ischemia-reperfusion injury. FASEB J 2020 02;34(2):2055-2074
Huang YF et al
2020/01/01
PubMed
117 Furlong RM et al. Alterations in &#x3B1;-synuclein and PINK1 expression reduce neurite length and induce mitochondrial fission and Golgi fragmentation in midbrain neurons. Neurosci Lett 2020 02;720:134777
Furlong RM et al
2020/01/01
PubMed
118 Wang X et al. Mechanisms underlying astrocytic connexin-43 autophagy degradation during cerebral ischemia injury and the effect on neuroinflammation and cell apoptosis. Biomed. Pharmacother. 2020 Jul;127:110125
Wang X et al
2020/01/01
PubMed
119 Sridevi Gurubaran I et al. Mitophagy in the Retinal Pigment Epithelium of Dry Age-Related Macular Degeneration Investigated in the <i>NFE2L2</i>/<i>PGC-1&#x3B1;</i><sup>-/-</sup> Mouse Model. Int J Mol Sci 2020 Mar;21(6)
Sridevi Gurubaran I et al
2020/01/01
PubMed
120 Lin Q et al. PINK1-parkin pathway of mitophagy protects against contrast-induced acute kidney injury via decreasing mitochondrial ROS and NLRP3 inflammasome activation. Redox Biol 2019 09;26:101254
Lin Q et al
2019/01/01
PubMed
121 Sarkar A et al. Ataxia telangiectasia mutated interacts with Parkin and induces mitophagy independent of kinase activity. Evidence from mantle cell lymphoma. Haematologica 2020 Feb;
Sarkar A et al
2020/01/01
PubMed
122 Igarashi R et al. Gemcitabine induces Parkin-independent mitophagy through mitochondrial-resident E3 ligase MUL1-mediated stabilization of PINK1. Sci Rep 2020 01;10(1):1465
Igarashi R et al
2020/01/01
PubMed
123 Verma M et al. Chronic treatment with the complex I inhibitor MPP<sup>+</sup> depletes endogenous PTEN-induced kinase 1 (PINK1) via up-regulation of Bcl-2-associated athanogene 6 (BAG6). J Biol Chem 2020 06;295(23):7865-7876
Verma M et al
2020/01/01
PubMed
124 Miyai T et al. Activation of PINK1-Parkin-Mediated Mitophagy Degrades Mitochondrial Quality Control Proteins in Fuchs Endothelial Corneal Dystrophy. Am J Pathol 2019 10;189(10):2061-2076
Miyai T et al
2019/01/01
PubMed
125 Fiesel FC et al. A specific subset of E2 ubiquitin-conjugating enzymes regulate Parkin activation and mitophagy differently. J Cell Sci 2014 Aug;127(Pt 16):3488-504
Fiesel FC et al
2014/01/01
PubMed
126 Tomita K et al. Lipid peroxidation increases hydrogen peroxide permeability leading to cell death in cancer cell lines that lack mtDNA. Cancer Sci 2019 Sep;110(9):2856-2866
Tomita K et al
2019/01/01
PubMed
127 Park SY et al. FUNDC1 regulates receptor-mediated mitophagy independently of the PINK1/Parkin-dependent pathway in rotenone-treated SH-SY5Y cells. Food Chem Toxicol 2020 Mar;137:111163
Park SY et al
2020/01/01
PubMed
128 Ren YZ et al. Resolvin D1 ameliorates cognitive impairment following traumatic brain injury via protecting astrocytic mitochondria. J Neurochem 2020 09;154(5):530-546
Ren YZ et al
2020/01/01
PubMed
129 Park H et al. Parkin Promotes Mitophagic Cell Death in Adult Hippocampal Neural Stem Cells Following Insulin Withdrawal. Front Mol Neurosci 2019;12:46
Park H et al
2019/01/01
PubMed
130 Riis S et al. IGF-1 Signalling Regulates Mitochondria Dynamics and Turnover through a Conserved GSK-3&#x3B2;-Nrf2-BNIP3 Pathway. Cells 2020 01;9(1)
Riis S et al
2020/01/01
PubMed
131 Bhupana JN et al. Gas7 knockout affects PINK1 expression and mitochondrial dynamics in mouse cortical neurons. FASEB Bioadv 2020 Mar;2(3):166-181
Bhupana JN et al
2020/01/01
PubMed
132 Qu F et al. Manipulation of Mitophagy by &quot;All-in-One&quot; nanosensitizer augments sonodynamic glioma therapy. Autophagy 2020 08;16(8):1413-1435
Qu F et al
2020/01/01
PubMed
133 Franco-Iborra S et al. Mutant HTT (huntingtin) impairs mitophagy in a cellular model of Huntington disease. Autophagy 2020 Feb;:1-18
Franco-Iborra S et al
2020/01/01
PubMed
134 Guardia-Laguarta C et al. PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation. J Neurosci 2019 09;39(36):7074-7085
Guardia-Laguarta C et al
2019/01/01
PubMed
135 Niu K et al. USP33 deubiquitinates PRKN/parkin and antagonizes its role in mitophagy. Autophagy 2020 04;16(4):724-734
Niu K et al
2020/01/01
PubMed
136 Yamano K et al. Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy. Elife 2014 Feb;3:e01612
Yamano K et al
2014/01/01
PubMed
137 Reddy AP et al. Selective serotonin reuptake inhibitor citalopram ameliorates cognitive decline and protects against amyloid beta-induced mitochondrial dynamics, biogenesis, autophagy, mitophagy and synaptic toxicities in a mouse model of Alzheimer&quot;s dise
Reddy AP et al
2021/01/01
PubMed
138 Ramakrishnan RK et al. Enhanced mitophagy in bronchial fibroblasts from severe asthmatic patients. PLoS One 2020;15(11):e0242695
Ramakrishnan RK et al
2020/01/01
PubMed
139 Uda M et al. Potential roles of neuronal nitric oxide synthase and the PTEN-induced kinase 1 (PINK1)/Parkin pathway for mitochondrial protein degradation in disuse-induced soleus muscle atrophy in adult rats. PLoS One 2020;15(12):e0243660
Uda M et al
2020/01/01
PubMed
140 Ragimbeau R et al. BAG6 promotes PINK1 signaling pathway and is essential for mitophagy. FASEB J 2021 02;35(2):e21361
Ragimbeau R et al
2021/01/01
PubMed
141 Cheng G et al. Mitochondria-targeted magnolol inhibits OXPHOS, proliferation, and tumor growth via modulation of energetics and autophagy in melanoma cells. Cancer Treat Res Commun 2020;25:100210
Cheng G et al
2020/01/01
PubMed
142 Yu X et al. Hyperoxia exposure arrests alveolarization in neonatal rats via PTEN&#x2011;induced putative kinase 1&#x2011;Parkin and Nip3&#x2011;like protein X&#x2011;mediated mitophagy disorders. Int J Mol Med 2020 Dec;46(6):2126-2136
Yu X et al
2020/01/01
PubMed
143 Xu Y et al. &#x3B4;-opioid receptor activation protects against Parkinson&quot;s disease-related mitochondrial dysfunction by enhancing PINK1/Parkin-dependent mitophagy. Aging (Albany NY) 2020 11;12(24):25035-25059
Xu Y et al
2020/01/01
PubMed
144 Roca-Agujetas V et al. Cholesterol alters mitophagy by impairing optineurin recruitment and lysosomal clearance in Alzheimer&quot;s disease. Mol Neurodegener 2021 03;16(1):15
Roca-Agujetas V et al
2021/01/01
PubMed
145 Anzell AR et al. Mitochondrial fission and mitophagy are independent mechanisms regulating ischemia/reperfusion injury in primary neurons. Cell Death Dis 2021 05;12(5):475
Anzell AR et al
2021/01/01
PubMed
146 Wang BY et al. Stress increases MHC-I expression in dopaminergic neurons and induces autoimmune activation in Parkinson&quot;s disease. Neural Regen Res 2021 Dec;16(12):2521-2527
Wang BY et al
2021/01/01
PubMed
147 Huang E et al. PINK1-mediated phosphorylation of LETM1 regulates mitochondrial calcium transport and protects neurons against mitochondrial stress. Nat Commun 2017 Nov;8(1):1399
Huang E et al
2017/01/01
PubMed
148 Lefebvre V et al. Genome-wide RNAi screen identifies ATPase inhibitory factor 1 (ATPIF1) as essential for PARK2 recruitment and mitophagy. Autophagy 2013 Nov;9(11):1770-9
Lefebvre V et al
2013/01/01
PubMed
149 Shiba-Fukushima K et al. Evidence that phosphorylated ubiquitin signaling is involved in the etiology of Parkinson&quot;s disease. Hum Mol Genet 2017 08;26(16):3172-3185
Shiba-Fukushima K et al
2017/01/01
PubMed
150 Bertolin G et al. The TOMM machinery is a molecular switch in PINK1 and PARK2/PARKIN-dependent mitochondrial clearance. Autophagy 2013 Nov;9(11):1801-17
Bertolin G et al
2013/01/01
PubMed
151 Wang H et al. Ghrelin protects against rotenone-induced cytotoxicity: Involvement of mitophagy and the AMPK/SIRT1/PGC1&#x3B1; pathway. Neuropeptides 2021 Jun;87:102134
Wang H et al
2021/01/01
PubMed
152 Okatsu K et al. Unconventional PINK1 localization to the outer membrane of depolarized mitochondria drives Parkin recruitment. J Cell Sci 2015 Mar;128(5):964-78
Okatsu K et al
2015/01/01
PubMed
153 Requejo-Aguilar R et al. PINK1 deficiency sustains cell proliferation by reprogramming glucose metabolism through HIF1. Nat Commun 2014;5:4514
Requejo-Aguilar R et al
2014/01/01
PubMed
154 Song Y et al. Involvement of impaired autophagy and mitophagy in Neuro-2a cell damage under hypoxic and/or high-glucose conditions. Sci Rep 2018 02;8(1):3301
Song Y et al
2018/01/01
PubMed
155 Soman SK et al. Cleaved PINK1 induces neuronal plasticity through PKA-mediated BDNF functional regulation. J Neurosci Res 2021 Sep;99(9):2134-2155
Soman SK et al
2021/01/01
PubMed
156 Wu D et al. Sestrin 2 protects against LPS-induced acute lung injury by inducing mitophagy in alveolar macrophages. Life Sci 2021 Feb;267:118941
Wu D et al
2021/01/01
PubMed
157 Choi GE et al. BNIP3L/NIX-mediated mitophagy protects against glucocorticoid-induced synapse defects. Nat Commun 2021 01;12(1):487
Choi GE et al
2021/01/01
PubMed
158 Miyahara K et al. BRCA1 degradation in response to mitochondrial damage in breast cancer cells. Sci Rep 2021 Apr;11(1):8735
Miyahara K et al
2021/01/01
PubMed
159 Berndsen K et al. PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins. Elife 2019 10;8
Berndsen K et al
2019/01/01
PubMed
160 Vangrieken P et al. Hypoxia-induced mitochondrial abnormalities in cells of the placenta. PLoS One 2021;16(1):e0245155
Vangrieken P et al
2021/01/01
PubMed
161 Ausman J et al. Ceramide-induced BOK promotes mitochondrial fission in preeclampsia. Cell Death Dis 2018 02;9(3):298
Ausman J et al
2018/01/01
PubMed
162 Tai Y et al. miR-34a-5p regulates PINK1-mediated mitophagy via multiple modes. Life Sci 2021 Jul;276:119415
Tai Y et al
2021/01/01
PubMed
163 Zhang X et al. CaMKIV regulates mitochondrial dynamics during sepsis. Cell Calcium 2020 12;92:102286
Zhang X et al
2020/01/01
PubMed
164 Wang C et al. PINK1-mediated mitophagy maintains pluripotency through optineurin. Cell Prolif 2021 May;54(5):e13034
Wang C et al
2021/01/01
PubMed
165 Cucarull B et al. Antioxidants Threaten Multikinase Inhibitor Efficacy against Liver Cancer by Blocking Mitochondrial Reactive Oxygen Species. Antioxidants (Basel) 2021 Aug;10(9)
Cucarull B et al
2021/01/01
Species: Human, Applications: WB PubMed
166 Baiano C et al. Interactions between interoception and perspective-taking: Current state of research and future directions. Neurosci Biobehav Rev 2021 11;130:252-262
Baiano C et al
2021/01/01
Species: Mouse, Applications: WB PubMed
  • No.: 1
  • 文献情報:
    Qi Z et al. Loss of PINK1 function decreases PP2A activity and promotes autophagy in dopaminergic cells and a murine model. Neurochem. Int. 2011 Oct;59(5):572-81
    Qi Z et al
    2011/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 2
  • 文献情報:
    Cui M et al. Perturbations in mitochondrial dynamics induced by human mutant PINK1 can be rescued by the mitochondrial division inhibitor mdivi-1. J. Biol. Chem. 2010 Apr;285(15):11740-52
    Cui M et al
    2010/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 3
  • 文献情報:
    Liu W et al. PINK1 defect causes mitochondrial dysfunction, proteasomal deficit and alpha-synuclein aggregation in cell culture models of Parkinson&quot;s disease. PLoS ONE 2009;4(2):e4597
    Liu W et al
    2009/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 4
  • 文献情報:
    Weihofen A et al. Pink1 Parkinson mutations, the Cdc37/Hsp90 chaperones and Parkin all influence the maturation or subcellular distribution of Pink1. Hum. Mol. Genet. 2008 Feb;17(4):602-16
    Weihofen A et al
    2008/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 5
  • 文献情報:
    Cui J et al. Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family. Science 2010 Sep;329(5996):1215-8
    Cui J et al
    2010/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 6
  • 文献情報:
    Meissner C et al. The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking. J. Neurochem. 2011 Jun;117(5):856-67
    Meissner C et al
    2011/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 7
  • 文献情報:
    Zhou C et al. The kinase domain of mitochondrial PINK1 faces the cytoplasm. Proc. Natl. Acad. Sci. U.S.A. 2008 Aug;105(33):12022-7
    Zhou C et al
    2008/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 8
  • 文献情報:
    Exner N et al. Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin. J. Neurosci. 2007 Nov;27(45):12413-8
    Exner N et al
    2007/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 9
  • 文献情報:
    Puccetti L et al. Evaluation of the effectiveness and safety of etodolac in prolonged treatment of active osteoarthritis. Int J Clin Pharmacol Res 1991;11(3):143-58
    Puccetti L et al
    1991/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 10
  • 文献情報:
    Kondapalli C et al. PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65. Open Biol 2012 May;2(5):120080
    Kondapalli C et al
    2012/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 11
  • 文献情報:
    Okatsu K et al. PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria. Nat Commun 2012 Aug;3:1016
    Okatsu K et al
    2012/01/01
  • 備考:
    Species: Human, Mouse, Applications: WB, ICC/IF
  • 参照:
    PubMed
  • No.: 12
  • 文献情報:
    Mitsuhashi S et al. Muscle choline kinase beta defect causes mitochondrial dysfunction and increased mitophagy. Hum. Mol. Genet. 2011 Oct;20(19):3841-51
    Mitsuhashi S et al
    2011/01/01
  • 備考:
    Applications: IHC, ICC/IF
  • 参照:
    PubMed
  • No.: 13
  • 文献情報:
    Sekine S et al. Rhomboid protease PARL mediates the mitochondrial membrane potential loss-induced cleavage of PGAM5. J. Biol. Chem. 2012 Oct;287(41):34635-45
    Sekine S et al
    2012/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 14
  • 文献情報:
    Lin W et al. Characterization of PINK1 processing, stability, and subcellular localization. J. Neurochem. 2008 Jul;106(1):464-74
    Lin W et al
    2008/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 15
  • 文献情報:
    Song S et al. Characterization of PINK1 (PTEN-induced putative kinase 1) mutations associated with Parkinson disease in mammalian cells and Drosophila. J. Biol. Chem. 2013 Feb;288(8):5660-72
    Song S et al
    2013/01/01
  • 備考:
    Species: Human, Applications: ICC/IF, WB
  • 参照:
    PubMed
  • No.: 16
  • 文献情報:
    Shiba-Fukushima K et al. PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy. Sci Rep 2012;2:1002
    Shiba-Fukushima K et al
    2012/01/01
  • 備考:
    Species: Mouse, Applications: WB
  • 参照:
    PubMed
  • No.: 17
  • 文献情報:
    Wood-Kaczmar A et al. The role of the mitochondrial NCX in the mechanism of neurodegeneration in Parkinson&quot;s disease. Adv. Exp. Med. Biol. 2013;961:241-9
    Wood-Kaczmar A et al
    2013/01/01
  • 備考:
    Species: Human, Applications: ICC/IF
  • 参照:
    PubMed
  • No.: 18
  • 文献情報:
    Irrcher I et al. Loss of the Parkinson&quot;s disease-linked gene DJ-1 perturbs mitochondrial dynamics. Hum. Mol. Genet. 2010 Oct;19(19):3734-46
    Irrcher I et al
    2010/01/01
  • 備考:
    Species: Mouse, Applications: WB
  • 参照:
    PubMed
  • No.: 19
  • 文献情報:
    Geisler S et al. The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations. Autophagy 2010 Oct;6(7):871-8
    Geisler S et al
    2010/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 20
  • 文献情報:
    Saita S et al. Selective escape of proteins from the mitochondria during mitophagy. Nat Commun 2013;4:1410
    Saita S et al
    2013/01/01
  • 備考:
    Species: Mouse, Applications: WB
  • 参照:
    PubMed
  • No.: 21
  • 文献情報:
    Gegg ME et al. Silencing of PINK1 expression affects mitochondrial DNA and oxidative phosphorylation in dopaminergic cells. PLoS ONE 2009;4(3):e4756
    Gegg ME et al
    2009/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 22
  • 文献情報:
    Narendra DP et al. PINK1 rendered temperature sensitive by disease-associated and engineered mutations. Hum. Mol. Genet. 2013 Jul;22(13):2572-89
    Narendra DP et al
    2013/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 23
  • 文献情報:
    Koyano F et al. The principal PINK1 and Parkin cellular events triggered in response to dissipation of mitochondrial membrane potential occur in primary neurons. Genes Cells 2013 Aug;18(8):672-81
    Koyano F et al
    2013/01/01
  • 備考:
    Species: Mouse, Applications: WB
  • 参照:
    PubMed
  • No.: 24
  • 文献情報:
    Hoshino A et al. Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart. Nat Commun 2013 Aug;4:2308
    Hoshino A et al
    2013/01/01
  • 備考:
    Species: Mouse, Applications: WB
  • 参照:
    PubMed
  • No.: 25
  • 文献情報:
    Iguchi M et al. Parkin-catalyzed ubiquitin-ester transfer is triggered by PINK1-dependent phosphorylation. J. Biol. Chem. 2013 Jul;288(30):22019-32
    Iguchi M et al
    2013/01/01
  • 備考:
    Species: Mouse, Applications: WB
  • 参照:
    PubMed
  • No.: 26
  • 文献情報:
    Murata H et al. SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria. Mol. Biol. Cell 2013 Sep;24(18):2772-84
    Murata H et al
    2013/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 27
  • 文献情報:
    Becker D et al. Pink1 kinase and its membrane potential (Delta&#x3C8;)-dependent cleavage product both localize to outer mitochondrial membrane by unique targeting mode. J. Biol. Chem. 2012 Jun;287(27):22969-87
    Becker D et al
    2012/01/01
  • 備考:
    Species: Human, Applications: WB, ICC/IF
  • 参照:
    PubMed
  • No.: 28
  • 文献情報:
    Holmstrom K. The Influence of the PD-associated Gene Products PINK1 and HtrA2/Omi on Mitochondrial Integrity Dissertation http://nbn-resolving.de/urn:nbn:de:bsz:21-opus-48153 2010 May 21 (WB, Human)

  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 29
  • 文献情報:
    Imai Y et al. The loss of PGAM5 suppresses the mitochondrial degeneration caused by inactivation of PINK1 in Drosophila. PLoS Genet. 2010;6(12):e1001229
    Imai Y et al
    2010/01/01
  • 備考:
    Species: Human, Applications: WB, ICC/IF
  • 参照:
    PubMed
  • No.: 30
  • 文献情報:
    Wang X et al. PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility. Cell 2011 Nov;147(4):893-906
    Wang X et al
    2011/01/01
  • 備考:
    Species: Human, Applications: WB, IP
  • 参照:
    PubMed
  • No.: 31
  • 文献情報:
    Kamp F et al. Inhibition of mitochondrial fusion by &#x3B1;-synuclein is rescued by PINK1, Parkin and DJ-1. EMBO J. 2010 Oct;29(20):3571-89
    Kamp F et al
    2010/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 32
  • 文献情報:
    Zhou ZD et al. Mutant PINK1 upregulates tyrosine hydroxylase and dopamine levels, leading to vulnerability of dopaminergic neurons. Free Radic. Biol. Med. 2014 Mar;68:220-33
    Zhou ZD et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 33
  • 文献情報:
    Okatsu K et al. A dimeric PINK1-containing complex on depolarized mitochondria stimulates Parkin recruitment. J. Biol. Chem. 2013 Dec;288(51):36372-84
    Okatsu K et al
    2013/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 34
  • 文献情報:
    Dagda RK et al. Beyond the mitochondrion: cytosolic PINK1 remodels dendrites through Protein Kinase A. J. Neurochem. 2014 Mar;128(6):864-77
    Dagda RK et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 35
  • 文献情報:
    Yamano K et al. PINK1 is degraded through the N-end rule pathway. Autophagy 2013 Nov;9(11):1758-69
    Yamano K et al
    2013/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 36
  • 文献情報:
    Montaigne D et al. Myocardial contractile dysfunction is associated with impaired mitochondrial function and dynamics in type 2 diabetic but not in obese patients. Circulation 2014 Aug;130(7):554-64
    Montaigne D et al
    2014/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 37
  • 文献情報:
    G坦mez-S叩nchez R et al. Mitochondrial impairment increases FL-PINK1 levels by calcium-dependent gene expression. Neurobiol. Dis. 2014 Feb;62:426-40
    G坦mez-S叩nchez R et al
    2014/01/01
  • 備考:
    Species: Human, Applications: WB, ICC/IF
  • 参照:
    PubMed
  • No.: 38
  • 文献情報:
    Lee S et al. Role of Glucose Metabolism and ATP in Maintaining PINK1 Levels during Parkin-mediated Mitochondrial Damage Responses. J. Biol. Chem. 2015 Jan;290(2):904-17
    Lee S et al
    2015/01/01
  • 備考:
    Species: Human, Mouse, Applications: WB
  • 参照:
    PubMed
  • No.: 39
  • 文献情報:
    McLelland GL et al. Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control. EMBO J. 2014 Feb;33(4):282-95
    McLelland GL et al
    2014/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 40
  • 文献情報:
    Shiba-Fukushima K et al. Lysine 63-linked polyubiquitination is dispensable for Parkin-mediated mitophagy. J. Biol. Chem. 2014 Nov;289(48):33131-6
    Shiba-Fukushima K et al
    2014/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 41
  • 文献情報:
    Patil KS et al. PARK13 regulates PINK1 and subcellular relocation patterns under oxidative stress in neurons. J. Neurosci. Res. 2014 Sep;92(9):1167-77
    Patil KS et al
    2014/01/01
  • 備考:
    Species: Human, Applications: Wb
  • 参照:
    PubMed
  • No.: 42
  • 文献情報:
    Mizumura K et al. Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD. J. Clin. Invest. 2014 Sep;124(9):3987-4003
    Mizumura K et al
    2014/01/01
  • 備考:
    Species: Human, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 43
  • 文献情報:
    Parganlija D et al. Loss of PINK1 impairs stress-induced autophagy and cell survival. PLoS ONE 2014;9(4):e95288
    Parganlija D et al
    2014/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 44
  • 文献情報:
    Kane LA et al. PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity. J. Cell Biol. 2014 Apr;205(2):143-53
    Kane LA et al
    2014/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 45
  • 文献情報:
    Choi HK et al. PINK1 positively regulates HDAC3 to suppress dopaminergic neuronal cell death. Hum. Mol. Genet. 2014 Oct;
    Choi HK et al
    2014/01/01
  • 備考:
    Species: Human, Applications: IP
  • 参照:
    PubMed
  • No.: 46
  • 文献情報:
    Koyano F et al. Ubiquitin is phosphorylated by PINK1 to activate parkin. Nature 2014 Jun;510(7503):162-6
    Koyano F et al
    2014/01/01
  • 備考:
    Species: Human, Mouse, Applications: WB
  • 参照:
    PubMed
  • No.: 47
  • 文献情報:
    Grenier K et al. Short mitochondrial ARF triggers Parkin/PINK1-dependent mitophagy. J. Biol. Chem. 2014 Oct;289(43):29519-30
    Grenier K et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 48
  • 文献情報:
    Shiba-Fukushima K et al. Phosphorylation of mitochondrial polyubiquitin by PINK1 promotes Parkin mitochondrial tethering. PLoS Genet. 2014 Dec;10(12):e1004861
    Shiba-Fukushima K et al
    2014/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 49
  • 文献情報:
    Bifsha P et al. Rgs6 is required for adult maintenance of dopaminergic neurons in the ventral substantia nigra. PLoS Genet. 2014 Dec;10(12):e1004863
    Bifsha P et al
    2014/01/01
  • 備考:
    Species: Mouse, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 50
  • 文献情報:
    Aerts L et al. PINK1 kinase catalytic activity is regulated by phosphorylation on serines 228 and 402. J. Biol. Chem. 2015 Jan;290(5):2798-811
    Aerts L et al
    2015/01/01
  • 備考:
    Applications: WB
  • 参照:
    PubMed
  • No.: 51
  • 文献情報:
    Bueno M et al. PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis. J. Clin. Invest. 2015 Feb;125(2):521-38
    Bueno M et al
    2015/01/01
  • 備考:
    Species: Mouse, Applications: WB
  • 参照:
    PubMed
  • No.: 52
  • 文献情報:
    Palubinsky AM et al. CHIP Is an Essential Determinant of Neuronal Mitochondrial Stress Signaling. Antioxid. Redox Signal. 2015 Mar;
    Palubinsky AM et al
    2015/01/01
  • 備考:
    Species: Mouse, Rat, Applications: WB, ICC/IF
  • 参照:
    PubMed
  • No.: 53
  • 文献情報:
    Han JY et al. Nitric Oxide Induction of Parkin Translocation in PTEN-induced Putative Kinase 1 (PINK1) Deficiency: FUNCTIONAL ROLE OF NEURONAL NITRIC OXIDE SYNTHASE DURING MITOPHAGY. J. Biol. Chem. 2015 Apr;290(16):10325-35
    Han JY et al
    2015/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 54
  • 文献情報:
    Duan X et al. Upregulation of human PINK1 gene expression by NF&#x3BA;B signalling. Mol Brain 2014;7:57
    Duan X et al
    2014/01/01
  • 備考:
    Applications: WB
  • 参照:
    PubMed
  • No.: 55
  • 文献情報:
    Lim GG et al. Cytosolic PTEN-induced Putative Kinase 1 Is Stabilized by the NF-&#x3BA;B Pathway and Promotes Non-selective Mitophagy. J. Biol. Chem. 2015 Jul;290(27):16882-93
    Lim GG et al
    2015/01/01
  • 備考:
    Species: Human, Applications: ICC/IF, IP
  • 参照:
    PubMed
  • No.: 56
  • 文献情報:
    Meissner C et al. Intramembrane protease PARL defines a negative regulator of PINK1- and PARK2/Parkin-dependent mitophagy. Autophagy 2015;11(9):1484-98
    Meissner C et al
    2015/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 57
  • 文献情報:
    Ivankovic D et al. Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy. J. Neurochem. 2015 Oct;
    Ivankovic D et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 58
  • 文献情報:
    Akabane S et al. Constitutive Activation of PINK1 Protein Leads to Proteasome-mediated and Non-apoptotic Cell Death Independently of Mitochondrial Autophagy. J. Biol. Chem. 2016 Jul;291(31):16162-74
    Akabane S et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 59
  • 文献情報:
    Kim J et al. miR-27a and miR-27b regulate autophagic clearance of damaged mitochondria by targeting PTEN-induced putative kinase 1 (PINK1). Mol Neurodegener 2016;11(1):55
    Kim J et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 60
  • 文献情報:
    Mart鱈n-Maestro P et al. PARK2 enhancement is able to compensate mitophagy alterations found in sporadic Alzheimer&quot;s disease. Hum. Mol. Genet. 2016 Feb;25(4):792-806
    Mart鱈n-Maestro P et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 61
  • 文献情報:
    Qu D et al. BAG2 Gene-mediated Regulation of PINK1 Protein Is Critical for Mitochondrial Translocation of PARKIN and Neuronal Survival. J. Biol. Chem. 2015 Dec;290(51):30441-52
    Qu D et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 62
  • 文献情報:
    Yue M et al. Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice. Neurobiol. Dis. 2015 Jun;78:172-95
    Yue M et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 63
  • 文献情報:
    Seillier M et al. Defects in mitophagy promote redox-driven metabolic syndrome in the absence of TP53INP1. EMBO Mol Med 2015 Jun;7(6):802-18
    Seillier M et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 64
  • 文献情報:
    Peng M et al. Inhibiting cytosolic translation and autophagy improves health in mitochondrial disease. Hum. Mol. Genet. 2015 Sep;24(17):4829-47
    Peng M et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 65
  • 文献情報:
    Scott TL et al. Polyubiquitination of apurinic/apyrimidinic endonuclease 1 by Parkin. Mol. Carcinog. 2016 May;
    Scott TL et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 66
  • 文献情報:
    Okatsu K et al. Phosphorylated ubiquitin chain is the genuine Parkin receptor. J. Cell Biol. 2015 Apr;209(1):111-28
    Okatsu K et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 67
  • 文献情報:
    Srivastava A et al. MKK3 deletion improves mitochondrial quality. Free Radic. Biol. Med. 2015 Oct;87:373-84
    Srivastava A et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 68
  • 文献情報:
    Park S et al. Pyruvate stimulates mitophagy via PINK1 stabilization. Cell. Signal. 2015 Sep;27(9):1824-30
    Park S et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 69
  • 文献情報:
    Gelmetti V et al. PINK1 and BECN1 relocalize at mitochondria-associated membranes during mitophagy and promote ER-mitochondria tethering and autophagosome formation. Autophagy 2017 Apr;13(4):654-669
    Gelmetti V et al
    2017/01/01
  • 備考:
    Species: Human, Applications: ICC/IF, WB, IP
  • 参照:
    PubMed
  • No.: 70
  • 文献情報:
    Zhang C et al. Sorafenib targets the mitochondrial electron transport chain complexes and ATP synthase to activate the PINK1-Parkin pathway and modulate cellular drug response. J. Biol. Chem. 2017 09;292(36):15105-15120
    Zhang C et al
    2017/01/01
  • 備考:
    Applications: WB
  • 参照:
    PubMed
  • No.: 71
  • 文献情報:
    Orr AL et al. Long-term oral kinetin does not protect against &#x3B1;-synuclein-induced neurodegeneration in rodent models of Parkinson&quot;s disease. Neurochem. Int. 2017 Oct;109:106-116
    Orr AL et al
    2017/01/01
  • 備考:
    WB
  • 参照:
    PubMed
  • No.: 72
  • 文献情報:
    Li GB et al. Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels. Oncotarget 2017 Feb;8(6):10359-10374
    Li GB et al
    2017/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 73
  • 文献情報:
    Yoo L et al. The ubiquitin E3 ligase CHIP promotes proteasomal degradation of the serine/threonine protein kinase PINK1 during staurosporine-induced cell death. J. Biol. Chem. 2018 01;293(4):1286-1297
    Yoo L et al
    2018/01/01
  • 備考:
    Species: Human, Applications:
  • 参照:
    PubMed
  • No.: 74
  • 文献情報:
    Mart鱈n-Maestro P et al. Mitophagy Failure in Fibroblasts and iPSC-Derived Neurons of Alzheimer&quot;s Disease-Associated Presenilin 1 Mutation. Front Mol Neurosci 2017;10:291
    Mart鱈n-Maestro P et al
    2017/01/01
  • 備考:
    Species: Human, Applications:
  • 参照:
    PubMed
  • No.: 75
  • 文献情報:
    Jin SM et al. The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria. Autophagy 2013 Nov;9(11):1750-7
    Jin SM et al
    2013/01/01
  • 備考:
    WB
  • 参照:
    PubMed
  • No.: 76
  • 文献情報:
    Sun X et al. Distinct multilevel misregulations of Parkin and PINK1 revealed in cell and animal models of TDP-43 proteinopathy. Cell Death Dis 2018 Sep;9(10):953
    Sun X et al
    2018/01/01
  • 備考:
    Species: Drosophila, Applications: WB
  • 参照:
    PubMed
  • No.: 77
  • 文献情報:
    Rossin F et al. Transglutaminase 2 ablation leads to mitophagy impairment associated with a metabolic shift towards aerobic glycolysis. Cell Death Differ. 2015 Mar;22(3):408-18
    Rossin F et al
    2015/01/01
  • 備考:
    WB
  • 参照:
    PubMed
  • No.: 78
  • 文献情報:
    Bartolom辿 A et al. MTORC1 Regulates both General Autophagy and Mitophagy Induction after Oxidative Phosphorylation Uncoupling. Mol. Cell. Biol. 2017 Sep;
    Bartolom辿 A et al
    2017/01/01
  • 備考:
    WB
  • 参照:
    PubMed
  • No.: 79
  • 文献情報:
    Weihofen A et al. Pink1 forms a multiprotein complex with Miro and Milton, linking Pink1 function to mitochondrial trafficking. Biochemistry 2009 Mar;48(9):2045-52
    Weihofen A et al
    2009/01/01
  • 備考:
    WB
  • 参照:
    PubMed
  • No.: 80
  • 文献情報:
    Jabir MS et al. Mitochondrial damage contributes to Pseudomonas aeruginosa activation of the inflammasome and is downregulated by autophagy. Autophagy 2015;11(1):166-82
    Jabir MS et al
    2015/01/01
  • 備考:
    WB
  • 参照:
    PubMed
  • No.: 81
  • 文献情報:
    Wettengel J et al. Harnessing human ADAR2 for RNA repair - Recoding a PINK1 mutation rescues mitophagy. Nucleic Acids Res. 2017 03;45(5):2797-2808
    Wettengel J et al
    2017/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 82
  • 文献情報:
    Xiao B et al. Reactive oxygen species trigger Parkin/PINK1 pathway-dependent mitophagy by inducing mitochondrial recruitment of Parkin. J. Biol. Chem. 2017 10;292(40):16697-16708
    Xiao B et al
    2017/01/01
  • 備考:
    WB
  • 参照:
    PubMed
  • No.: 83
  • 文献情報:
    Lazarou M et al. PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding. J. Cell Biol. 2013 Jan;200(2):163-72
    Lazarou M et al
    2013/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 84
  • 文献情報:
    Mizumura K et al. Sphingolipid regulation of lung epithelial cell mitophagy and necroptosis during cigarette smoke exposure. FASEB J. 2018 04;32(4):1880-1890
    Mizumura K et al
    2018/01/01
  • 備考:
    Species: Mouse, Applications:
  • 参照:
    PubMed
  • No.: 85
  • 文献情報:
    Jamil S et al. The small molecule 2-phenylethynesulfonamide induces covalent modification of p53. Biochem. Biophys. Res. Commun. 2017 Jan;482(1):154-158
    Jamil S et al
    2017/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 86
  • 文献情報:
    Goiran T et al. Nuclear p53-mediated repression of autophagy involves PINK1 transcriptional down-regulation. Cell Death Differ. 2018 May;25(5):873-884
    Goiran T et al
    2018/01/01
  • 備考:
    Species: Mouse, Applications: WB
  • 参照:
    PubMed
  • No.: 87
  • 文献情報:
    Kravic B et al. In mammalian skeletal muscle, phosphorylation of TOMM22 by protein kinase CSNK2/CK2 controls mitophagy. Autophagy 2018;14(2):311-335
    Kravic B et al
    2018/01/01
  • 備考:
    Species: Mouse, Applications:
  • 参照:
    PubMed
  • No.: 88
  • 文献情報:
    Ando M et al. The PINK1 p.I368N mutation affects protein stability and ubiquitin kinase activity. Mol Neurodegener 2017 04;12(1):32
    Ando M et al
    2017/01/01
  • 備考:
    Species: Human, Applications: WB, ICC/IF
  • 参照:
    PubMed
  • No.: 89
  • 文献情報:
    Wai T et al. The membrane scaffold SLP2 anchors a proteolytic hub in mitochondria containing PARL and the i-AAA protease YME1L. EMBO Rep. 2016 12;17(12):1844-1856
    Wai T et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 90
  • 文献情報:
    Xu Y et al. Cytoprotection against Hypoxic and/or MPP&#x207A; Injury: Effect of &#x3B4;-Opioid Receptor Activation on Caspase 3. Int J Mol Sci 2016 Aug;17(8)
    Xu Y et al
    2016/01/01
  • 備考:
    WB
  • 参照:
    PubMed
  • No.: 91
  • 文献情報:
    Hawk MA et al. RIPK1-mediated induction of mitophagy compromises the viability of extracellular-matrix-detached cells. Nat. Cell Biol. 2018 Mar;20(3):272-284
    Hawk MA et al
    2018/01/01
  • 備考:
    WB
  • 参照:
    PubMed
  • No.: 92
  • 文献情報:
    Bueno M et al. ATF3 represses PINK1 gene transcription in lung epithelial cells to control mitochondrial homeostasis. Aging Cell 2018 Apr;17(2)
    Bueno M et al
    2018/01/01
  • 備考:
    Species: Mouse, Applications: WB
  • 参照:
    PubMed
  • No.: 93
  • 文献情報:
    Basso V et al. Regulation of ER-mitochondria contacts by Parkin via Mfn2. Pharmacol. Res. 2018 Dec;138:43-56
    Basso V et al
    2018/01/01
  • 備考:
    Species: Mouse, Applications: WB
  • 参照:
    PubMed
  • No.: 94
  • 文献情報:
    Fiesel FC et al. Mitochondrial targeted HSP90 inhibitor Gamitrinib-TPP (G-TPP) induces PINK1/Parkin-dependent mitophagy. Oncotarget 2017 Dec;8(63):106233-106248
    Fiesel FC et al
    2017/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 95
  • 文献情報:
    Choubey V et al. BECN1 is involved in the initiation of mitophagy: it facilitates PARK2 translocation to mitochondria. Autophagy 2014 Jun;10(6):1105-19
    Choubey V et al
    2014/01/01
  • 備考:
    WB
  • 参照:
    PubMed
  • No.: 96
  • 文献情報:
    Tang C et al. PINK1-PRKN/PARK2 pathway of mitophagy is activated to protect against renal ischemia-reperfusion injury. Autophagy 2018;14(5):880-897
    Tang C et al
    2018/01/01
  • 備考:
    WB
  • 参照:
    PubMed
  • No.: 97
  • 文献情報:
    Walsh TG et al. Loss of the mitochondrial kinase PINK1 does not alter platelet function. Sci Rep 2018 Sep;8(1):14377
    Walsh TG et al
    2018/01/01
  • 備考:
    Species: Mouse, Applications: WB
  • 参照:
    PubMed
  • No.: 98
  • 文献情報:
    Kim H et al. CRISPR-Cas9 Mediated Telomere Removal Leads to Mitochondrial Stress and Protein Aggregation. Int J Mol Sci 2017 Oct;18(10)
    Kim H et al
    2017/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 99
  • 文献情報:
    Martinez A et al. Quantitative proteomic analysis of Parkin substrates in Drosophila neurons. Mol Neurodegener 2017 04;12(1):29
    Martinez A et al
    2017/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 100
  • 文献情報:
    Kumar A et al. SESN2 facilitates mitophagy by helping Parkin translocation through ULK1 mediated Beclin1 phosphorylation. Sci Rep 2018 Jan;8(1):615
    Kumar A et al
    2018/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 101
  • 文献情報:
    Mannam P et al. MKK3 influences mitophagy and is involved in cigarette smoke-induced inflammation. Free Radic. Biol. Med. 2016 12;101:102-115
    Mannam P et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 102
  • 文献情報:
    Biel TG et al. Mitochondrial dysfunction activates lysosomal-dependent mitophagy selectively in cancer cells. Oncotarget 2018 Jan;9(1):995-1011
    Biel TG et al
    2018/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 103
  • 文献情報:
    Thomas HE et al. Mitochondrial Complex I Activity Is Required for Maximal Autophagy. Cell Rep 2018 Aug;24(9):2404-2417.e8
    Thomas HE et al
    2018/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 104
  • 文献情報:
    Callegari S et al. Phospho-ubiquitin-PARK2 complex as a marker for mitophagy defects. Autophagy 2017 Jan;13(1):201-211
    Callegari S et al
    2017/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 105
  • 文献情報:
    Marcassa E et al. Dual role of USP30 in controlling basal pexophagy and mitophagy. EMBO Rep. 2018 Jul;19(7)
    Marcassa E et al
    2018/01/01
  • 備考:
    Species: Human, Applications:
  • 参照:
    PubMed
  • No.: 106
  • 文献情報:
    Sorrentino V et al. Enhancing mitochondrial proteostasis reduces amyloid-&#x3B2; proteotoxicity. Nature 2017 12;552(7684):187-193
    Sorrentino V et al
    2017/01/01
  • 備考:
    Species: Human, Applications:
  • 参照:
    PubMed
  • No.: 107
  • 文献情報:
    Zhang T et al. BNIP3 Protein Suppresses PINK1 Kinase Proteolytic Cleavage to Promote Mitophagy. J. Biol. Chem. 2016 Oct;291(41):21616-21629
    Zhang T et al
    2016/01/01
  • 備考:
    IP, ICC/IF
  • 参照:
    PubMed
  • No.: 108
  • 文献情報:
    Fiesel FC et al. (Patho-)physiological relevance of PINK1-dependent ubiquitin phosphorylation. EMBO Rep. 2015 Sep;16(9):1114-30
    Fiesel FC et al
    2015/01/01
  • 備考:
    WB
  • 参照:
    PubMed
  • No.: 109
  • 文献情報:
    Gu X et al. Lead (Pb) induced ATM-dependent mitophagy via PINK1/Parkin pathway. Toxicol. Lett. 2018 Jul;291:92-100
    Gu X et al
    2018/01/01
  • 備考:
    WB
  • 参照:
    PubMed
  • No.: 110
  • 文献情報:
    Sun Y et al. Beclin-1-Dependent Autophagy Protects the Heart During Sepsis. Circulation 2018 Nov;138(20):2247-2262
    Sun Y et al
    2018/01/01
  • 備考:
    Species: Mouse, Applications:
  • 参照:
    PubMed
  • No.: 111
  • 文献情報:
    Berezhnov AV et al. Intracellular pH Modulates Autophagy and Mitophagy. J. Biol. Chem. 2016 Apr;291(16):8701-8
    Berezhnov AV et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 112
  • 文献情報:
    Lin W et al. Structural determinants of PINK1 topology and dual subcellular distribution. BMC Cell Biol. 2010 Nov;11:90
    Lin W et al
    2010/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 113
  • 文献情報:
    Sato S et al. Induction of PINK1/Parkin-Mediated Mitophagy. Methods Mol. Biol. 2018;1759:9-17
    Sato S et al
    2018/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 114
  • 文献情報:
    Gu C et al. Salidroside Ameliorates Mitochondria-Dependent Neuronal Apoptosis after Spinal Cord Ischemia-Reperfusion Injury Partially through Inhibiting Oxidative Stress and Promoting Mitophagy. Oxid Med Cell Longev 2020;2020:3549704
    Gu C et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 115
  • 文献情報:
    Nikolaou PE et al. Chronic Empagliflozin Treatment Reduces Myocardial Infarct Size in Nondiabetic Mice Through STAT-3-Mediated Protection on Microvascular Endothelial Cells and Reduction of Oxidative Stress. Antioxid Redox Signal 2021 03;34(7):551-571
    Nikolaou PE et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 116
  • 文献情報:
    Huang YF et al. The protective effort of GPCR kinase 2-interacting protein-1 in neurons via promoting Beclin1-Parkin induced mitophagy at the early stage of spinal cord ischemia-reperfusion injury. FASEB J 2020 02;34(2):2055-2074
    Huang YF et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 117
  • 文献情報:
    Furlong RM et al. Alterations in &#x3B1;-synuclein and PINK1 expression reduce neurite length and induce mitochondrial fission and Golgi fragmentation in midbrain neurons. Neurosci Lett 2020 02;720:134777
    Furlong RM et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 118
  • 文献情報:
    Wang X et al. Mechanisms underlying astrocytic connexin-43 autophagy degradation during cerebral ischemia injury and the effect on neuroinflammation and cell apoptosis. Biomed. Pharmacother. 2020 Jul;127:110125
    Wang X et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 119
  • 文献情報:
    Sridevi Gurubaran I et al. Mitophagy in the Retinal Pigment Epithelium of Dry Age-Related Macular Degeneration Investigated in the <i>NFE2L2</i>/<i>PGC-1&#x3B1;</i><sup>-/-</sup> Mouse Model. Int J Mol Sci 2020 Mar;21(6)
    Sridevi Gurubaran I et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 120
  • 文献情報:
    Lin Q et al. PINK1-parkin pathway of mitophagy protects against contrast-induced acute kidney injury via decreasing mitochondrial ROS and NLRP3 inflammasome activation. Redox Biol 2019 09;26:101254
    Lin Q et al
    2019/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 121
  • 文献情報:
    Sarkar A et al. Ataxia telangiectasia mutated interacts with Parkin and induces mitophagy independent of kinase activity. Evidence from mantle cell lymphoma. Haematologica 2020 Feb;
    Sarkar A et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 122
  • 文献情報:
    Igarashi R et al. Gemcitabine induces Parkin-independent mitophagy through mitochondrial-resident E3 ligase MUL1-mediated stabilization of PINK1. Sci Rep 2020 01;10(1):1465
    Igarashi R et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 123
  • 文献情報:
    Verma M et al. Chronic treatment with the complex I inhibitor MPP<sup>+</sup> depletes endogenous PTEN-induced kinase 1 (PINK1) via up-regulation of Bcl-2-associated athanogene 6 (BAG6). J Biol Chem 2020 06;295(23):7865-7876
    Verma M et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 124
  • 文献情報:
    Miyai T et al. Activation of PINK1-Parkin-Mediated Mitophagy Degrades Mitochondrial Quality Control Proteins in Fuchs Endothelial Corneal Dystrophy. Am J Pathol 2019 10;189(10):2061-2076
    Miyai T et al
    2019/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 125
  • 文献情報:
    Fiesel FC et al. A specific subset of E2 ubiquitin-conjugating enzymes regulate Parkin activation and mitophagy differently. J Cell Sci 2014 Aug;127(Pt 16):3488-504
    Fiesel FC et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 126
  • 文献情報:
    Tomita K et al. Lipid peroxidation increases hydrogen peroxide permeability leading to cell death in cancer cell lines that lack mtDNA. Cancer Sci 2019 Sep;110(9):2856-2866
    Tomita K et al
    2019/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 127
  • 文献情報:
    Park SY et al. FUNDC1 regulates receptor-mediated mitophagy independently of the PINK1/Parkin-dependent pathway in rotenone-treated SH-SY5Y cells. Food Chem Toxicol 2020 Mar;137:111163
    Park SY et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 128
  • 文献情報:
    Ren YZ et al. Resolvin D1 ameliorates cognitive impairment following traumatic brain injury via protecting astrocytic mitochondria. J Neurochem 2020 09;154(5):530-546
    Ren YZ et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 129
  • 文献情報:
    Park H et al. Parkin Promotes Mitophagic Cell Death in Adult Hippocampal Neural Stem Cells Following Insulin Withdrawal. Front Mol Neurosci 2019;12:46
    Park H et al
    2019/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 130
  • 文献情報:
    Riis S et al. IGF-1 Signalling Regulates Mitochondria Dynamics and Turnover through a Conserved GSK-3&#x3B2;-Nrf2-BNIP3 Pathway. Cells 2020 01;9(1)
    Riis S et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 131
  • 文献情報:
    Bhupana JN et al. Gas7 knockout affects PINK1 expression and mitochondrial dynamics in mouse cortical neurons. FASEB Bioadv 2020 Mar;2(3):166-181
    Bhupana JN et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 132
  • 文献情報:
    Qu F et al. Manipulation of Mitophagy by &quot;All-in-One&quot; nanosensitizer augments sonodynamic glioma therapy. Autophagy 2020 08;16(8):1413-1435
    Qu F et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 133
  • 文献情報:
    Franco-Iborra S et al. Mutant HTT (huntingtin) impairs mitophagy in a cellular model of Huntington disease. Autophagy 2020 Feb;:1-18
    Franco-Iborra S et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 134
  • 文献情報:
    Guardia-Laguarta C et al. PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation. J Neurosci 2019 09;39(36):7074-7085
    Guardia-Laguarta C et al
    2019/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 135
  • 文献情報:
    Niu K et al. USP33 deubiquitinates PRKN/parkin and antagonizes its role in mitophagy. Autophagy 2020 04;16(4):724-734
    Niu K et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 136
  • 文献情報:
    Yamano K et al. Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy. Elife 2014 Feb;3:e01612
    Yamano K et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 137
  • 文献情報:
    Reddy AP et al. Selective serotonin reuptake inhibitor citalopram ameliorates cognitive decline and protects against amyloid beta-induced mitochondrial dynamics, biogenesis, autophagy, mitophagy and synaptic toxicities in a mouse model of Alzheimer&quot;s dise
    Reddy AP et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 138
  • 文献情報:
    Ramakrishnan RK et al. Enhanced mitophagy in bronchial fibroblasts from severe asthmatic patients. PLoS One 2020;15(11):e0242695
    Ramakrishnan RK et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 139
  • 文献情報:
    Uda M et al. Potential roles of neuronal nitric oxide synthase and the PTEN-induced kinase 1 (PINK1)/Parkin pathway for mitochondrial protein degradation in disuse-induced soleus muscle atrophy in adult rats. PLoS One 2020;15(12):e0243660
    Uda M et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 140
  • 文献情報:
    Ragimbeau R et al. BAG6 promotes PINK1 signaling pathway and is essential for mitophagy. FASEB J 2021 02;35(2):e21361
    Ragimbeau R et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 141
  • 文献情報:
    Cheng G et al. Mitochondria-targeted magnolol inhibits OXPHOS, proliferation, and tumor growth via modulation of energetics and autophagy in melanoma cells. Cancer Treat Res Commun 2020;25:100210
    Cheng G et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 142
  • 文献情報:
    Yu X et al. Hyperoxia exposure arrests alveolarization in neonatal rats via PTEN&#x2011;induced putative kinase 1&#x2011;Parkin and Nip3&#x2011;like protein X&#x2011;mediated mitophagy disorders. Int J Mol Med 2020 Dec;46(6):2126-2136
    Yu X et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 143
  • 文献情報:
    Xu Y et al. &#x3B4;-opioid receptor activation protects against Parkinson&quot;s disease-related mitochondrial dysfunction by enhancing PINK1/Parkin-dependent mitophagy. Aging (Albany NY) 2020 11;12(24):25035-25059
    Xu Y et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 144
  • 文献情報:
    Roca-Agujetas V et al. Cholesterol alters mitophagy by impairing optineurin recruitment and lysosomal clearance in Alzheimer&quot;s disease. Mol Neurodegener 2021 03;16(1):15
    Roca-Agujetas V et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 145
  • 文献情報:
    Anzell AR et al. Mitochondrial fission and mitophagy are independent mechanisms regulating ischemia/reperfusion injury in primary neurons. Cell Death Dis 2021 05;12(5):475
    Anzell AR et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 146
  • 文献情報:
    Wang BY et al. Stress increases MHC-I expression in dopaminergic neurons and induces autoimmune activation in Parkinson&quot;s disease. Neural Regen Res 2021 Dec;16(12):2521-2527
    Wang BY et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 147
  • 文献情報:
    Huang E et al. PINK1-mediated phosphorylation of LETM1 regulates mitochondrial calcium transport and protects neurons against mitochondrial stress. Nat Commun 2017 Nov;8(1):1399
    Huang E et al
    2017/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 148
  • 文献情報:
    Lefebvre V et al. Genome-wide RNAi screen identifies ATPase inhibitory factor 1 (ATPIF1) as essential for PARK2 recruitment and mitophagy. Autophagy 2013 Nov;9(11):1770-9
    Lefebvre V et al
    2013/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 149
  • 文献情報:
    Shiba-Fukushima K et al. Evidence that phosphorylated ubiquitin signaling is involved in the etiology of Parkinson&quot;s disease. Hum Mol Genet 2017 08;26(16):3172-3185
    Shiba-Fukushima K et al
    2017/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 150
  • 文献情報:
    Bertolin G et al. The TOMM machinery is a molecular switch in PINK1 and PARK2/PARKIN-dependent mitochondrial clearance. Autophagy 2013 Nov;9(11):1801-17
    Bertolin G et al
    2013/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 151
  • 文献情報:
    Wang H et al. Ghrelin protects against rotenone-induced cytotoxicity: Involvement of mitophagy and the AMPK/SIRT1/PGC1&#x3B1; pathway. Neuropeptides 2021 Jun;87:102134
    Wang H et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 152
  • 文献情報:
    Okatsu K et al. Unconventional PINK1 localization to the outer membrane of depolarized mitochondria drives Parkin recruitment. J Cell Sci 2015 Mar;128(5):964-78
    Okatsu K et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 153
  • 文献情報:
    Requejo-Aguilar R et al. PINK1 deficiency sustains cell proliferation by reprogramming glucose metabolism through HIF1. Nat Commun 2014;5:4514
    Requejo-Aguilar R et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 154
  • 文献情報:
    Song Y et al. Involvement of impaired autophagy and mitophagy in Neuro-2a cell damage under hypoxic and/or high-glucose conditions. Sci Rep 2018 02;8(1):3301
    Song Y et al
    2018/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 155
  • 文献情報:
    Soman SK et al. Cleaved PINK1 induces neuronal plasticity through PKA-mediated BDNF functional regulation. J Neurosci Res 2021 Sep;99(9):2134-2155
    Soman SK et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 156
  • 文献情報:
    Wu D et al. Sestrin 2 protects against LPS-induced acute lung injury by inducing mitophagy in alveolar macrophages. Life Sci 2021 Feb;267:118941
    Wu D et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 157
  • 文献情報:
    Choi GE et al. BNIP3L/NIX-mediated mitophagy protects against glucocorticoid-induced synapse defects. Nat Commun 2021 01;12(1):487
    Choi GE et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 158
  • 文献情報:
    Miyahara K et al. BRCA1 degradation in response to mitochondrial damage in breast cancer cells. Sci Rep 2021 Apr;11(1):8735
    Miyahara K et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 159
  • 文献情報:
    Berndsen K et al. PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins. Elife 2019 10;8
    Berndsen K et al
    2019/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 160
  • 文献情報:
    Vangrieken P et al. Hypoxia-induced mitochondrial abnormalities in cells of the placenta. PLoS One 2021;16(1):e0245155
    Vangrieken P et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 161
  • 文献情報:
    Ausman J et al. Ceramide-induced BOK promotes mitochondrial fission in preeclampsia. Cell Death Dis 2018 02;9(3):298
    Ausman J et al
    2018/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 162
  • 文献情報:
    Tai Y et al. miR-34a-5p regulates PINK1-mediated mitophagy via multiple modes. Life Sci 2021 Jul;276:119415
    Tai Y et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 163
  • 文献情報:
    Zhang X et al. CaMKIV regulates mitochondrial dynamics during sepsis. Cell Calcium 2020 12;92:102286
    Zhang X et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 164
  • 文献情報:
    Wang C et al. PINK1-mediated mitophagy maintains pluripotency through optineurin. Cell Prolif 2021 May;54(5):e13034
    Wang C et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 165
  • 文献情報:
    Cucarull B et al. Antioxidants Threaten Multikinase Inhibitor Efficacy against Liver Cancer by Blocking Mitochondrial Reactive Oxygen Species. Antioxidants (Basel) 2021 Aug;10(9)
    Cucarull B et al
    2021/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 166
  • 文献情報:
    Baiano C et al. Interactions between interoception and perspective-taking: Current state of research and future directions. Neurosci Biobehav Rev 2021 11;130:252-262
    Baiano C et al
    2021/01/01
  • 備考:
    Species: Mouse, Applications: WB
  • 参照:
    PubMed