価格表
在庫・価格 : 2025年05月01日 23時38分 現在
商品名 | 商品コード | メーカー | 包装 | 価格 | 在庫 | リスト |
---|---|---|---|---|---|---|
Anti-PINK1, Rabbit-Poly <Anti-PTEN Induced Putative Kinase Protein 1> データシート |
BC100-494 |
NOVノバス バイオロジカルス Novus biologicals, LLC |
0.1 ml | ¥113,000 |
無 (未発注) |
追加 |
在庫・価格 : 2025年05月01日 23時38分 現在
使用文献
- No.: 1
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文献情報:
Qi Z et al. Loss of PINK1 function decreases PP2A activity and promotes autophagy in dopaminergic cells and a murine model. Neurochem. Int. 2011 Oct;59(5):572-81
Qi Z et al
2011/01/01
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文献情報:
Cui M et al. Perturbations in mitochondrial dynamics induced by human mutant PINK1 can be rescued by the mitochondrial division inhibitor mdivi-1. J. Biol. Chem. 2010 Apr;285(15):11740-52
Cui M et al
2010/01/01
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備考:
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参照:
- No.: 3
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文献情報:
Liu W et al. PINK1 defect causes mitochondrial dysfunction, proteasomal deficit and alpha-synuclein aggregation in cell culture models of Parkinson's disease. PLoS ONE 2009;4(2):e4597
Liu W et al
2009/01/01
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備考:
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参照:
- No.: 4
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文献情報:
Weihofen A et al. Pink1 Parkinson mutations, the Cdc37/Hsp90 chaperones and Parkin all influence the maturation or subcellular distribution of Pink1. Hum. Mol. Genet. 2008 Feb;17(4):602-16
Weihofen A et al
2008/01/01
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備考:
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- No.: 5
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文献情報:
Cui J et al. Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family. Science 2010 Sep;329(5996):1215-8
Cui J et al
2010/01/01
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備考:
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参照:
- No.: 6
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文献情報:
Meissner C et al. The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking. J. Neurochem. 2011 Jun;117(5):856-67
Meissner C et al
2011/01/01
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備考:
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参照:
- No.: 7
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文献情報:
Zhou C et al. The kinase domain of mitochondrial PINK1 faces the cytoplasm. Proc. Natl. Acad. Sci. U.S.A. 2008 Aug;105(33):12022-7
Zhou C et al
2008/01/01
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備考:
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参照:
- No.: 8
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文献情報:
Exner N et al. Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin. J. Neurosci. 2007 Nov;27(45):12413-8
Exner N et al
2007/01/01
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参照:
- No.: 9
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文献情報:
Puccetti L et al. Evaluation of the effectiveness and safety of etodolac in prolonged treatment of active osteoarthritis. Int J Clin Pharmacol Res 1991;11(3):143-58
Puccetti L et al
1991/01/01
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備考:
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参照:
- No.: 10
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文献情報:
Kondapalli C et al. PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65. Open Biol 2012 May;2(5):120080
Kondapalli C et al
2012/01/01
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備考:
Species: Human, Applications: WB -
参照:
- No.: 11
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文献情報:
Okatsu K et al. PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria. Nat Commun 2012 Aug;3:1016
Okatsu K et al
2012/01/01
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備考:
Species: Human, Mouse, Applications: WB, ICC/IF -
参照:
- No.: 12
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文献情報:
Mitsuhashi S et al. Muscle choline kinase beta defect causes mitochondrial dysfunction and increased mitophagy. Hum. Mol. Genet. 2011 Oct;20(19):3841-51
Mitsuhashi S et al
2011/01/01
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備考:
Applications: IHC, ICC/IF -
参照:
- No.: 13
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文献情報:
Sekine S et al. Rhomboid protease PARL mediates the mitochondrial membrane potential loss-induced cleavage of PGAM5. J. Biol. Chem. 2012 Oct;287(41):34635-45
Sekine S et al
2012/01/01
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備考:
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参照:
- No.: 14
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文献情報:
Lin W et al. Characterization of PINK1 processing, stability, and subcellular localization. J. Neurochem. 2008 Jul;106(1):464-74
Lin W et al
2008/01/01
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備考:
Species: Human, Applications: WB -
参照:
- No.: 15
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文献情報:
Song S et al. Characterization of PINK1 (PTEN-induced putative kinase 1) mutations associated with Parkinson disease in mammalian cells and Drosophila. J. Biol. Chem. 2013 Feb;288(8):5660-72
Song S et al
2013/01/01
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備考:
Species: Human, Applications: ICC/IF, WB -
参照:
- No.: 16
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文献情報:
Shiba-Fukushima K et al. PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy. Sci Rep 2012;2:1002
Shiba-Fukushima K et al
2012/01/01
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備考:
Species: Mouse, Applications: WB -
参照:
- No.: 17
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文献情報:
Wood-Kaczmar A et al. The role of the mitochondrial NCX in the mechanism of neurodegeneration in Parkinson's disease. Adv. Exp. Med. Biol. 2013;961:241-9
Wood-Kaczmar A et al
2013/01/01
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備考:
Species: Human, Applications: ICC/IF -
参照:
- No.: 18
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文献情報:
Irrcher I et al. Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics. Hum. Mol. Genet. 2010 Oct;19(19):3734-46
Irrcher I et al
2010/01/01
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備考:
Species: Mouse, Applications: WB -
参照:
- No.: 19
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文献情報:
Geisler S et al. The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations. Autophagy 2010 Oct;6(7):871-8
Geisler S et al
2010/01/01
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備考:
Species: Human, Applications: WB -
参照:
- No.: 20
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文献情報:
Saita S et al. Selective escape of proteins from the mitochondria during mitophagy. Nat Commun 2013;4:1410
Saita S et al
2013/01/01
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備考:
Species: Mouse, Applications: WB -
参照:
- No.: 21
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文献情報:
Gegg ME et al. Silencing of PINK1 expression affects mitochondrial DNA and oxidative phosphorylation in dopaminergic cells. PLoS ONE 2009;4(3):e4756
Gegg ME et al
2009/01/01
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備考:
Species: Human, Applications: WB -
参照:
- No.: 22
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文献情報:
Narendra DP et al. PINK1 rendered temperature sensitive by disease-associated and engineered mutations. Hum. Mol. Genet. 2013 Jul;22(13):2572-89
Narendra DP et al
2013/01/01
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備考:
Species: Human, Applications: WB -
参照:
- No.: 23
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文献情報:
Koyano F et al. The principal PINK1 and Parkin cellular events triggered in response to dissipation of mitochondrial membrane potential occur in primary neurons. Genes Cells 2013 Aug;18(8):672-81
Koyano F et al
2013/01/01
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備考:
Species: Mouse, Applications: WB -
参照:
- No.: 24
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文献情報:
Hoshino A et al. Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart. Nat Commun 2013 Aug;4:2308
Hoshino A et al
2013/01/01
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備考:
Species: Mouse, Applications: WB -
参照:
- No.: 25
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文献情報:
Iguchi M et al. Parkin-catalyzed ubiquitin-ester transfer is triggered by PINK1-dependent phosphorylation. J. Biol. Chem. 2013 Jul;288(30):22019-32
Iguchi M et al
2013/01/01
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備考:
Species: Mouse, Applications: WB -
参照:
- No.: 26
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文献情報:
Murata H et al. SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria. Mol. Biol. Cell 2013 Sep;24(18):2772-84
Murata H et al
2013/01/01
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備考:
Species: Human, Applications: WB -
参照:
- No.: 27
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文献情報:
Becker D et al. Pink1 kinase and its membrane potential (Deltaψ)-dependent cleavage product both localize to outer mitochondrial membrane by unique targeting mode. J. Biol. Chem. 2012 Jun;287(27):22969-87
Becker D et al
2012/01/01
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備考:
Species: Human, Applications: WB, ICC/IF -
参照:
- No.: 28
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文献情報:
Holmstrom K. The Influence of the PD-associated Gene Products PINK1 and HtrA2/Omi on Mitochondrial Integrity Dissertation http://nbn-resolving.de/urn:nbn:de:bsz:21-opus-48153 2010 May 21 (WB, Human)
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備考:
Species: Human, Applications: WB -
参照:
- No.: 29
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文献情報:
Imai Y et al. The loss of PGAM5 suppresses the mitochondrial degeneration caused by inactivation of PINK1 in Drosophila. PLoS Genet. 2010;6(12):e1001229
Imai Y et al
2010/01/01
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備考:
Species: Human, Applications: WB, ICC/IF -
参照:
- No.: 30
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文献情報:
Wang X et al. PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility. Cell 2011 Nov;147(4):893-906
Wang X et al
2011/01/01
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備考:
Species: Human, Applications: WB, IP -
参照:
- No.: 31
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文献情報:
Kamp F et al. Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1. EMBO J. 2010 Oct;29(20):3571-89
Kamp F et al
2010/01/01
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備考:
Species: Human, Applications: WB -
参照:
- No.: 32
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文献情報:
Zhou ZD et al. Mutant PINK1 upregulates tyrosine hydroxylase and dopamine levels, leading to vulnerability of dopaminergic neurons. Free Radic. Biol. Med. 2014 Mar;68:220-33
Zhou ZD et al
2014/01/01
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備考:
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参照:
- No.: 33
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文献情報:
Okatsu K et al. A dimeric PINK1-containing complex on depolarized mitochondria stimulates Parkin recruitment. J. Biol. Chem. 2013 Dec;288(51):36372-84
Okatsu K et al
2013/01/01
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備考:
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参照:
- No.: 34
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文献情報:
Dagda RK et al. Beyond the mitochondrion: cytosolic PINK1 remodels dendrites through Protein Kinase A. J. Neurochem. 2014 Mar;128(6):864-77
Dagda RK et al
2014/01/01
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備考:
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参照:
- No.: 35
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文献情報:
Yamano K et al. PINK1 is degraded through the N-end rule pathway. Autophagy 2013 Nov;9(11):1758-69
Yamano K et al
2013/01/01
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備考:
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参照:
- No.: 36
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文献情報:
Montaigne D et al. Myocardial contractile dysfunction is associated with impaired mitochondrial function and dynamics in type 2 diabetic but not in obese patients. Circulation 2014 Aug;130(7):554-64
Montaigne D et al
2014/01/01
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備考:
Species: Human, Applications: WB -
参照:
- No.: 37
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文献情報:
G坦mez-S叩nchez R et al. Mitochondrial impairment increases FL-PINK1 levels by calcium-dependent gene expression. Neurobiol. Dis. 2014 Feb;62:426-40
G坦mez-S叩nchez R et al
2014/01/01
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備考:
Species: Human, Applications: WB, ICC/IF -
参照:
- No.: 38
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文献情報:
Lee S et al. Role of Glucose Metabolism and ATP in Maintaining PINK1 Levels during Parkin-mediated Mitochondrial Damage Responses. J. Biol. Chem. 2015 Jan;290(2):904-17
Lee S et al
2015/01/01
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備考:
Species: Human, Mouse, Applications: WB -
参照:
- No.: 39
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文献情報:
McLelland GL et al. Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control. EMBO J. 2014 Feb;33(4):282-95
McLelland GL et al
2014/01/01
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備考:
Species: Human, Applications: WB -
参照:
- No.: 40
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文献情報:
Shiba-Fukushima K et al. Lysine 63-linked polyubiquitination is dispensable for Parkin-mediated mitophagy. J. Biol. Chem. 2014 Nov;289(48):33131-6
Shiba-Fukushima K et al
2014/01/01
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備考:
Species: Human, Applications: WB -
参照:
- No.: 41
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文献情報:
Patil KS et al. PARK13 regulates PINK1 and subcellular relocation patterns under oxidative stress in neurons. J. Neurosci. Res. 2014 Sep;92(9):1167-77
Patil KS et al
2014/01/01
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備考:
Species: Human, Applications: Wb -
参照:
- No.: 42
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文献情報:
Mizumura K et al. Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD. J. Clin. Invest. 2014 Sep;124(9):3987-4003
Mizumura K et al
2014/01/01
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備考:
Species: Human, Applications: IHC-P -
参照:
- No.: 43
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文献情報:
Parganlija D et al. Loss of PINK1 impairs stress-induced autophagy and cell survival. PLoS ONE 2014;9(4):e95288
Parganlija D et al
2014/01/01
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備考:
Species: Human, Applications: WB -
参照:
- No.: 44
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文献情報:
Kane LA et al. PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity. J. Cell Biol. 2014 Apr;205(2):143-53
Kane LA et al
2014/01/01
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備考:
Species: Human, Applications: WB -
参照:
- No.: 45
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文献情報:
Choi HK et al. PINK1 positively regulates HDAC3 to suppress dopaminergic neuronal cell death. Hum. Mol. Genet. 2014 Oct;
Choi HK et al
2014/01/01
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備考:
Species: Human, Applications: IP -
参照:
- No.: 46
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文献情報:
Koyano F et al. Ubiquitin is phosphorylated by PINK1 to activate parkin. Nature 2014 Jun;510(7503):162-6
Koyano F et al
2014/01/01
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備考:
Species: Human, Mouse, Applications: WB -
参照:
- No.: 47
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文献情報:
Grenier K et al. Short mitochondrial ARF triggers Parkin/PINK1-dependent mitophagy. J. Biol. Chem. 2014 Oct;289(43):29519-30
Grenier K et al
2014/01/01
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備考:
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参照:
- No.: 48
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文献情報:
Shiba-Fukushima K et al. Phosphorylation of mitochondrial polyubiquitin by PINK1 promotes Parkin mitochondrial tethering. PLoS Genet. 2014 Dec;10(12):e1004861
Shiba-Fukushima K et al
2014/01/01
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備考:
Species: Human, Applications: WB -
参照:
- No.: 49
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文献情報:
Bifsha P et al. Rgs6 is required for adult maintenance of dopaminergic neurons in the ventral substantia nigra. PLoS Genet. 2014 Dec;10(12):e1004863
Bifsha P et al
2014/01/01
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備考:
Species: Mouse, Applications: IHC-P -
参照:
- No.: 50
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文献情報:
Aerts L et al. PINK1 kinase catalytic activity is regulated by phosphorylation on serines 228 and 402. J. Biol. Chem. 2015 Jan;290(5):2798-811
Aerts L et al
2015/01/01
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備考:
Applications: WB -
参照:
- No.: 51
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文献情報:
Bueno M et al. PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis. J. Clin. Invest. 2015 Feb;125(2):521-38
Bueno M et al
2015/01/01
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備考:
Species: Mouse, Applications: WB -
参照:
- No.: 52
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文献情報:
Palubinsky AM et al. CHIP Is an Essential Determinant of Neuronal Mitochondrial Stress Signaling. Antioxid. Redox Signal. 2015 Mar;
Palubinsky AM et al
2015/01/01
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備考:
Species: Mouse, Rat, Applications: WB, ICC/IF -
参照:
- No.: 53
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文献情報:
Han JY et al. Nitric Oxide Induction of Parkin Translocation in PTEN-induced Putative Kinase 1 (PINK1) Deficiency: FUNCTIONAL ROLE OF NEURONAL NITRIC OXIDE SYNTHASE DURING MITOPHAGY. J. Biol. Chem. 2015 Apr;290(16):10325-35
Han JY et al
2015/01/01
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備考:
Species: Human, Applications: WB -
参照:
- No.: 54
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文献情報:
Duan X et al. Upregulation of human PINK1 gene expression by NFκB signalling. Mol Brain 2014;7:57
Duan X et al
2014/01/01
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備考:
Applications: WB -
参照:
- No.: 55
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文献情報:
Lim GG et al. Cytosolic PTEN-induced Putative Kinase 1 Is Stabilized by the NF-κB Pathway and Promotes Non-selective Mitophagy. J. Biol. Chem. 2015 Jul;290(27):16882-93
Lim GG et al
2015/01/01
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備考:
Species: Human, Applications: ICC/IF, IP -
参照:
- No.: 56
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文献情報:
Meissner C et al. Intramembrane protease PARL defines a negative regulator of PINK1- and PARK2/Parkin-dependent mitophagy. Autophagy 2015;11(9):1484-98
Meissner C et al
2015/01/01
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備考:
Species: Human, Applications: WB -
参照:
- No.: 57
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文献情報:
Ivankovic D et al. Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy. J. Neurochem. 2015 Oct;
Ivankovic D et al
2015/01/01
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備考:
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参照:
- No.: 58
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文献情報:
Akabane S et al. Constitutive Activation of PINK1 Protein Leads to Proteasome-mediated and Non-apoptotic Cell Death Independently of Mitochondrial Autophagy. J. Biol. Chem. 2016 Jul;291(31):16162-74
Akabane S et al
2016/01/01
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備考:
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参照:
- No.: 59
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文献情報:
Kim J et al. miR-27a and miR-27b regulate autophagic clearance of damaged mitochondria by targeting PTEN-induced putative kinase 1 (PINK1). Mol Neurodegener 2016;11(1):55
Kim J et al
2016/01/01
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備考:
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参照:
- No.: 60
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文献情報:
Mart鱈n-Maestro P et al. PARK2 enhancement is able to compensate mitophagy alterations found in sporadic Alzheimer's disease. Hum. Mol. Genet. 2016 Feb;25(4):792-806
Mart鱈n-Maestro P et al
2016/01/01
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備考:
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参照:
- No.: 61
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文献情報:
Qu D et al. BAG2 Gene-mediated Regulation of PINK1 Protein Is Critical for Mitochondrial Translocation of PARKIN and Neuronal Survival. J. Biol. Chem. 2015 Dec;290(51):30441-52
Qu D et al
2015/01/01
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備考:
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参照:
- No.: 62
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文献情報:
Yue M et al. Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice. Neurobiol. Dis. 2015 Jun;78:172-95
Yue M et al
2015/01/01
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備考:
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参照:
- No.: 63
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文献情報:
Seillier M et al. Defects in mitophagy promote redox-driven metabolic syndrome in the absence of TP53INP1. EMBO Mol Med 2015 Jun;7(6):802-18
Seillier M et al
2015/01/01
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備考:
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参照:
- No.: 64
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文献情報:
Peng M et al. Inhibiting cytosolic translation and autophagy improves health in mitochondrial disease. Hum. Mol. Genet. 2015 Sep;24(17):4829-47
Peng M et al
2015/01/01
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備考:
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参照:
- No.: 65
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文献情報:
Scott TL et al. Polyubiquitination of apurinic/apyrimidinic endonuclease 1 by Parkin. Mol. Carcinog. 2016 May;
Scott TL et al
2016/01/01
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備考:
-
参照:
- No.: 66
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文献情報:
Okatsu K et al. Phosphorylated ubiquitin chain is the genuine Parkin receptor. J. Cell Biol. 2015 Apr;209(1):111-28
Okatsu K et al
2015/01/01
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備考:
-
参照:
- No.: 67
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文献情報:
Srivastava A et al. MKK3 deletion improves mitochondrial quality. Free Radic. Biol. Med. 2015 Oct;87:373-84
Srivastava A et al
2015/01/01
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備考:
-
参照:
- No.: 68
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文献情報:
Park S et al. Pyruvate stimulates mitophagy via PINK1 stabilization. Cell. Signal. 2015 Sep;27(9):1824-30
Park S et al
2015/01/01
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備考:
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参照:
- No.: 69
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文献情報:
Gelmetti V et al. PINK1 and BECN1 relocalize at mitochondria-associated membranes during mitophagy and promote ER-mitochondria tethering and autophagosome formation. Autophagy 2017 Apr;13(4):654-669
Gelmetti V et al
2017/01/01
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備考:
Species: Human, Applications: ICC/IF, WB, IP -
参照:
- No.: 70
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文献情報:
Zhang C et al. Sorafenib targets the mitochondrial electron transport chain complexes and ATP synthase to activate the PINK1-Parkin pathway and modulate cellular drug response. J. Biol. Chem. 2017 09;292(36):15105-15120
Zhang C et al
2017/01/01
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備考:
Applications: WB -
参照:
- No.: 71
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文献情報:
Orr AL et al. Long-term oral kinetin does not protect against α-synuclein-induced neurodegeneration in rodent models of Parkinson's disease. Neurochem. Int. 2017 Oct;109:106-116
Orr AL et al
2017/01/01
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備考:
WB -
参照:
- No.: 72
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文献情報:
Li GB et al. Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels. Oncotarget 2017 Feb;8(6):10359-10374
Li GB et al
2017/01/01
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備考:
Species: Human, Applications: WB -
参照:
- No.: 73
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文献情報:
Yoo L et al. The ubiquitin E3 ligase CHIP promotes proteasomal degradation of the serine/threonine protein kinase PINK1 during staurosporine-induced cell death. J. Biol. Chem. 2018 01;293(4):1286-1297
Yoo L et al
2018/01/01
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備考:
Species: Human, Applications: -
参照:
- No.: 74
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文献情報:
Mart鱈n-Maestro P et al. Mitophagy Failure in Fibroblasts and iPSC-Derived Neurons of Alzheimer's Disease-Associated Presenilin 1 Mutation. Front Mol Neurosci 2017;10:291
Mart鱈n-Maestro P et al
2017/01/01
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備考:
Species: Human, Applications: -
参照:
- No.: 75
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文献情報:
Jin SM et al. The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria. Autophagy 2013 Nov;9(11):1750-7
Jin SM et al
2013/01/01
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備考:
WB -
参照:
- No.: 76
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文献情報:
Sun X et al. Distinct multilevel misregulations of Parkin and PINK1 revealed in cell and animal models of TDP-43 proteinopathy. Cell Death Dis 2018 Sep;9(10):953
Sun X et al
2018/01/01
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備考:
Species: Drosophila, Applications: WB -
参照:
- No.: 77
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文献情報:
Rossin F et al. Transglutaminase 2 ablation leads to mitophagy impairment associated with a metabolic shift towards aerobic glycolysis. Cell Death Differ. 2015 Mar;22(3):408-18
Rossin F et al
2015/01/01
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備考:
WB -
参照:
- No.: 78
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文献情報:
Bartolom辿 A et al. MTORC1 Regulates both General Autophagy and Mitophagy Induction after Oxidative Phosphorylation Uncoupling. Mol. Cell. Biol. 2017 Sep;
Bartolom辿 A et al
2017/01/01
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備考:
WB -
参照:
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